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Slide 2 ISM Unit 4 Genetics Slide 3 A:B: ChromosomeGenotype #1 A specific part of a DNA that when transcribed and Translated forms a specific polypeptide. C:D: AlleleGene Slide 4 D Slide 5 A:B: MutationInsertion mutation #2 The insertion of an incorrect nucleotide is C:D: Base substitution mutation DNA doesnt make mistakes!! Slide 6 C Slide 7 A:B: LeucineValine #3 Glutamic acid is the amino acid that should Be coded on hemoglobin, but for Sickle-cell Anemia this amino acid is coded for C:D: GlycineTyrosine Slide 8 B Slide 9 A:B: Interphase IInterphase II #4 Crossing over occurs in C:D: Prophase IProphase II Slide 10 C Slide 11 A:B: Mitosis forms 2 haploid cells Meiosis forms 4 diploid cells #5 One difference between meiosis and mitosis is C:D: Mitosis produces genetically different cells Meiosis produces genetically different cells Slide 12 D Slide 13 A:B: Length and widthBanding patterns and length #6 Chromosomes can be distinguished on Karyograms by what 2 features? C:D: Homologous pairsThe centromere and homologous pair Slide 14 B Slide 15 A:B: 50% homozygous recessive 50% Heterozygous #7 If 2 heterozgyous parents had offspring What are the possible genotypes? C:D: 100% Homozygous100% Heterozygous Slide 16 B Slide 17 A:B: It gives you the DNA profile It separates the base pairs #8 Polymerase chain reaction (PCR) is useful for forensics because C:D: Makes millions of copies of the DNA Uses ligase to cut the DNA Slide 18 C Slide 19 A:B: Size and chargeSize of the DNA fragments #9 Gel electrophoresis separates DNA by C:D: Charge of the DNAThe amount of DNA Slide 20 A Slide 21 A:B: Transfer of DNATransfer of Chromosomes #10 Genetic engineering involves C:D: Transfer of GenesTransfer of the nucleus Slide 22 C Slide 23 A:B: The genetic code is universal Most amino acids are transferred #11 Gene transfer is possible because C:D: Factor IX allows for the transfer mRNA can transfer Slide 24 A Slide 25 A:B: Obtain the desired gene Attach the DNA to a vector #12 What steps are need for gene transfer C:D: Culture the bacteriaAll of the above Slide 26 D Slide 27 A:B: Increase food production Tolerance to extreme weather #13 Benefits of GMOs are.. C:D: Disease resistantAll of the above Slide 28 D Slide 29 A:B: Used to clone peopleUsed to make stem cells #14 Therapeutic cloning is C:D: Used to make tissues or organs Can be used with DNA from other species Slide 30 C Slide 31 A:B: Ligase and mRNA polymerase mRNA polymerase and helicase #15 What two enzymes are used to make recombinant plasmid C:D: Ligase and restriction enzyme Restriction enzyme and mRNA polymerase Slide 32 C Slide 33 Great Job!!!! Great Job!!!! Thank you for playing! Thank you for playing!