lung cancer morphologic diagnostic guidelines – czech experience · lung cancer morphologic...
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Lung cancer morphologic diagnosticguidelines – Czech experience
Aleš RyškaUniversity Hospital, Hradec Králové
Lung cancer in Czech republic
Travis WD et al. J Thorac Oncol. 2011;6(2):244-85.
Rossi et al; International Journal of Surgical Pathology / Vol. 17, No. 3, June 2009
NSCLC
Morphology NOS
AC SC
Morphology + immunohistochemistry
SCAC NOS
CK7
Poorly differentiated NSCLC, favor adenoca
Pathologist = partner of the clinician
Pure morphology immunohistochemistry Molecular genetics+ +
Czech guidelines
• Printed version distributed to all pathologists• Freely available for clinicians• Electronic version available online• Material is obligatory to anybody providing
morphological diagnosis of LC• Controled during audits of laboratories• Recently slight changes (ALK)