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8/7/2019 Meds for Med surg-wendy

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8/7/2019 Meds for Med surg-wendy

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Medication

Trade/Generic Classification

Patient Dose 

Dose Limits

Uses/Purpose

Mode of Action 

Side Effects 

Adverse Reactions 

Contraindications  

 Nursing Implications 

Time(s) to

 be given Pre/post

admin Labs/VS to

consider  

Colace/

docusate sodium OTC

Adult: PO 50-

300 mg/day(docusate

sodium) or 240mg (docusate

calcium or docusate

 potassium) prnEnema 4 ml

(docusatesodium)

Available forms:

Docusatecalcium: caps

240 mg;docusate

sodium: caps 50,100, 250 mg;

tabs 100 mg; syr 20 mg/5 ml, 50

mg/15 ml, 100mg/30 ml, 150

mg/15 ml; oralsol 10, 50

mg/ml; enema283 mg/3.9 g

cap

Uses: To soften

stools, preventconstipation,

soften fecalimpaction (rectal

route)

Action: Increaseswater, fat

 penetration inintestine; allows

for easier passageof stool; increases

electrolyte, water secretion in colon

Therapeutic

outcome:Passage of 

softened stool,absence of 

constipation

EENT: Bitter taste, throat

irritation

GI: Nausea, anorexia,cramps, diarrhea

INTEG: Rash

Contraindications:

Hypersensitivity,obstruction, fecal

impaction,nausea/vomiting

Precautions:

Pregnancy C, breastfeeding

 Nursing:

Assess cramping,rectal bleeding,

nausea, vomiting; if these symptoms

occur, product should be discontinued;

identify cause of constipation; identify

whether fluids, bulk,or exercise is missing

from lifestyle

Dilute oral

sol in juice or 

other fluidto disguise

taste

Give tabsor caps

with 8 ozof liquid;

give onempty

stomachfor 

increasedabsorption

, results

 N/A

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Medication

Trade/GenericClassification

Patient Dose

Dose Limits

Uses/Purpose

Mode of Action

Side Effects

Adverse Reactions

Contraindications

 Nursing Implications

Time(s) to

 be given

Pre/post

adminLabs/VS to

consider 

Senakot S  Adult:

PO 1-8 tabs/day ½ to 4 tsp of 

granules added towater or juice 

RECT SUPP

1-2 at bedtime 

SYRUP 1-4 tsp at bedtime

(1 tsp = 4 ml), 7.5-15 ml; (Black 

Draught) ¾ oz

dissolved in 2.5 ozof liquid given

 between 2-

4 PM the day before procedure(X-Prep) 

Availableforms: Tabs 6,

8.6, 15, 25 mg;granules 15, 20mg/5 ml; syr 8.8

mg/5 ml; liquid

33.3 mg/ml 

Uses: Acute

constipation; bowel preparation for 

surgery or exam,

 prevention of constipation in those

taking opiates longterm 

Action: Stimulates

 peristalsis by actionon Auerbach's

 plexus; softens feces

 by increasing water and electrolytes in

large intestine 

GI: Nausea, vomiting,

anorexia, abdominal cramps, diarrhea, flatulence 

GU: Pink-red or brown-black 

discoloration of urine 

META: Hypocalcemia,

enteropathy, alkalosis,

hypokalemia, tetany 

Contraindications: 

Breastfeeding,hypersensitivity, GI

 bleeding, intestinal

obstruction, CHF,abdominal pain,

nausea/vomiting,appendicitis, acutesurgical abdomen 

Nursing: Assess cramping, rectal

 bleeding, nausea,

vomiting; if these

symptoms occur, product

should be discontinued;

identify cause of 

constipation; identify

whether fluids, bulk, or 

exercise is missing fromlifestyle Assess for magnesium

toxicity: thirst, confusion,decrease in reflexes

Monitor blood ammonia

level (30-70 mg/100 ml);

monitor for clearing of 

confusion, lethargy,

restlessness, irritability

(hepatic encephalopathy)

Once per 

day 

Monitor: 

-Blood-Urine

-Electrolytes

if used often by patient -Check I&Oratio toidentify fluid

loss 

-Monitor  bloodammonia 

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Medication

Trade/Generic

Classification

Patient Dose

Dose Limits

Uses/Purpose

Mode of Action

Side Effects

Adverse Reactions

Contraindications

 Nursing Implications

Time(s) to

 be given

Pre/post admin

Labs/VS to

consider 

Lisinopril/Prinivil, Zestril

 F unc. class.: 

Antihypertensive,angiotensin converting

enzyme (ACE) inhibitor 

Hypertension  Adult: PO 10-40

mg/day; may

increase to 80mg/day if required

Geriatric: PO 2.5-5

mg/day, increaseq7day

CHF  Adult: PO 5 mg

initially withdiuretics/digoxin,

range 5-20 mg

Available forms: Tabs 2.5, 5, 10, 20,

30 40 mg

Action: Selectively

suppresses renin-

angiotensin-

aldosterone system;inhibits ACE; prevents

conversion of 

angiotensin I to

angiotensin II; resultsin dilatation of arterial,

venous vessels

Therapeutic

outcome: DecreasedB/P in hypertension,

decreased preload,

afterload in CHF

Uses: Mild to

moderatehypertension,

adjunctive therapy of 

systolic CHF, acuteMI

CNS : V ertigo, depression, stroke,

insomnia, paresthesias, headache, 

fatigue, asthenia, dizziness

CV : Chest pain, hypotension

 EE  NT : Blurred vision, nasal

congestion

GI: Nausea, vomiting, anorexia,

constipation, flatulence, GIirritation, diarrhea

GU: Proteinuria, renalinsufficiency, sexual dysfunction,

impotence

 I  NT  EG: Rash, pruritus

 MI  SC : Muscle cramps,

hyperkalemia

 RE  SP : Dry cough, dyspnea

 SYST : Angioedema 

Contraindications: Hypersensitivity,

angioedema

Assessment -Assess blood studies:

 platelets, WBC with

differential, baseline,

 periodically q3mo; if neutrophils <1000/mm3,

discontinue treatment

-Monitor B/P, check for orthostatic hypotension,

syncope; if changesoccur, dosage change may

 be required

-baselines in renal, liver 

function tests before

therapy begins

-Monitor renal, liver function tests: protein,

BUN, creatinine; watch

for increased levels thatmay indicate nephrotic

syndrome and renal

failure; monitor renal

symptoms: polyuria,

oliguria, frequency,

dysuria

-Check potassium levels

throughout treatment,

-Check for edema

-Assess for allergicreactions: rash, fever,

 pruritus, urticaria; product

Onset 1 hr 

Peak  6-8 hr 

Duration 24 hr 

Interference:

glucose/insulin

tolerance tests,

ANA titer 

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fibrillation, atrial

flutter, atrialtachycardia;

cardiogenic shock, paroxysmal atrial

tachycardia

-Monitor ECG continuouslyduring parenteral loadingdoses and for patients withsuspected toxicity; provide

hemodynamic monitoringfor patients with heart failureor administer multiplecardiac products

closemonitoring isnecessaryStore

 protectedfrom light

MedicationTrade/Generic

Classification

Patient Dose

Dose Limits

Uses/Purpose

Mode of Action

Side Effects

Adverse Reactions

Contraindications

 Nursing Implications

Time(s) to be given

Pre/postadmin

Labs/VS toconsider 

Zocor/Simvastatin

 F unc.class.: Antilipide

mic

C hem. class.: HMG-CoA reductase

inhibitor 

Adult: PO 20

mg/dayin PM initially,

usual range 5-40mg/day daily in PM,

max 80 mg/day;

dosage adjustments

may be made at 4-

wk intervals or 

more; those taking

verapamil, max 20mg/day

Renal dose/those

taking gemfibrozil,

danazol Adult: PO 5 mg

day, initially; CCr 

<20 ml/min 5 mg qd

in the evening

Cardiac/renal

transplantation Adult: PO 5

mg/day, max 10mg/day

With amiodarone

or verapamil 

Adult: PO max 20mg/day

Action: Inhibits

HMG-CoAreductase enzyme,

which reducescholesterol

synthesis; thisenzyme is needed

for cholesterol

 production

Therapeutic

outcome:Decreasing

cholesterol levelsand LDLs,

increased HDLs

Uses: As anadjunct in primary

hypercholesterolemia (types IIa,

IIb), isolatedhypertriglyceridem

ia (Frederickson

type IV) and typeIII

CNS: Headache, ALS (Lou

Gehrig's disease) 

EENT: Lens opacities

GI: Nausea, constipation,diarrhea, dyspepsia, flatus,

abdominal pain, liver

dysfunction, pancreatitis 

INTEG: Rash, pruritus,

 photosensitivity

MS: Muscle cramps,myalgia, myositis,

rhabdomyolysis 

RESP: Upper respiratorytract infection

Contraindications: 

Pregnancy X,  breastfeeding,

hypersensitivity,active liver disease

Nursing Implications-Assess nutrition: fat,

 protein, carbohydrates;

nutritional analysis should be completed by dietitian

 before treatment is

initiated

Assess for 

rhabdomyolysis: muscle

tenderness, increased

CPK levels; therapy

should be discontinued

- Monitor bowel patterndaily; diarrhea may be a

 problem

- Monitor triglycerides,

cholesterol baseline,throughout treatment;

LDL, HDL, triglycerides

and cholesterol should be

watched closely at 6-8 wk 

and q6mo; if increased,

Give 30 min

 before AM and PM meals 

Increased:

CPK, liver function tests

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DVT/PE Adult: SUBCUT

5000 units q8-12hr 

Heparin flush 

 Adult and child: IV 10-100

units/ml 

coagulation (DIC) immediately; HIT may occur after product discontinuation

- Monitor for 

hypersensitivity: fever, skinrash, urticaria; notify prescriber immediately

Medication

Trade/GenericClassification

Patient Dose

Dose Limits

Uses/Purpose

Mode of Action

Side Effects

Adverse Reactions

Contraindications

 Nursing Implications

Time(s) to

 be given

Pre/post

adminLabs/VS to

consider 

Fragmin/ Dalteparin

 F unc.

class.: Anticoagulant

C hem. class.: Low-molecular-weight

heparin

Hip replacement

surgery/DVT

prophylaxis  

Adult: SUBCUT2500 international

units 2 hr before

surgery and 2nd

dose in the evening

the day of surgery

(4-8 hr postop), then

5000 internationalunits SUBCUT 1st

 postop day anddaily 5-10 days

Unstable

angina/non-Q-

wave MI Adult: SUBCUT

120 international

units/kg q12hr × 5-8

days; max 10,000

international unitsq12hr × 5-8 dayswith concurrentaspirin, continue

until stable

Deep vein

thrombosis,

prophylaxis for

abdominal surgery Adult: SUBCUT

2500 international

Action: Inhibits

factor Xa/IIa(thrombin),

resulting inanticoagulation

Therapeutic

outcome: Absenceof deep vein

thrombosis

Uses: Unstableangina/non-Q-wave MI;

 prevention of deepvein thrombosis in

abdominal surgery,

hip replacement patients or thosewith restricted

mobility duringacute illness;

 pulmonaryembolism

CNS : Intracranial bleeding 

 HEMA: 

Thrombocytopenia 

INTEG: Pruritus, superficialwound infection

SYST: Hypersensitivity, he

morrhage,anaphylaxis possible

Contraindications: Hypersensitivity to this

 product, heparin, pork 

 products, benzyl alcohol;active major bleeding,

hemophilia, leukemia

with bleeding,

thrombocytopenic

 purpura, cerebrovascular 

hemorrhage, cerebral

aneurysm, thoseundergoing regional

anesthesia for unstableangina, non-Q-wave MI,dalteparin-induced

thrombocytopenia

Nursing Implications-Assess for bleeding (Hct,

occult blood in stools)

during treatment since

 bleeding can occur 

- Assess for bleedinggums, petechiae,ecchymosis, black tarrystools, hematuria,

epistaxis, decrease in Hct,

B/P; may indicate

 bleeding, possible

hemorrhage; notify

  prescriber immediately;

 product should bediscontinued

-Assess for 

Drug

 peaks 4hours after 

administration

Hct, Occult

Blood

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units daily, evening

 prior to abdominal

surgery and repeat

daily × 5-10 days; in

high-risk patients

5000 international

units should be used

hypersensitivity: fever,

skin rash, urticaria; notify

 prescriber immediately

- Assess for needed

dosage change q1-2wk;

dose may need to be

decreased if bleedingoccurs

Medication

Trade/GenericClassification

Patient Dose

Dose Limits

Uses/Purpose

Mode of Action

Side Effects

Adverse Reactions

Contraindications

 Nursing Implications

Time(s) to

 be given

Pre/post

adminLabs/VS to

consider 

Morphine/

morphine sulfate,Morphitec

 F unc. class.: Opioid

analgesic

C hem. class.: Alkaloid

Adult:

SUBCUT/IM 5-20 mg q4hr prn;

PO 10-30 mgq4hr prn;

EXT REL 15-30mg q8-12hr;

RECT 10-20 mgq4hr prn; IV 2.5-15 mg diluted in

4-5 ml of water for inj, over 5

min;

SUS REL cap(Kadian), EXT

REL cap(Avinza) give

total daily doseq24hr; for those

with notolerance to

opioids, 30mg/day, may

adjust by no

Action: Depresses

 pain impulsetransmission at the

spinal cord level by interacting with

opioid receptors

Therapeutic

outcome: Decreas

ed pain

Uses: Moderate to

severe pain

CNS: Drowsiness,

dizziness, confusion, headache, sedation, euphoria,

insomnia, seizures 

CV: Palpitations, bradycard

ia, change in B/P, shock,

cardiac arrest, chest pain,

hyper/hypotension,

edema, tachycardia 

EENT: Tinnitus, blurred

vision, miosis, diplopia

GI: Nausea, vomiting,anorexia, constipation, cram

 ps, biliary tract pressure

GU: Urinary retention

 HEMA: 

Thrombocytopenia 

INTEG: Rash, urticaria,

 bruising, flushing,diaphoresis, pruritus

Contraindications: 

Hypersensitivity,addiction (opioid),

hemorrhage, bronchialasthma, increased ICP 

Nursing

Implications

- Assess pain: location,type, character, intensity;give dose before pain

 becomes extreme

- Monitor I&O ratio;

check for decreasing

output; may indicate

urinary retention; check 

for constipation; increase

fluids, bulk in diet if needed, or stimulantlaxatives may be

 prescribed

- Monitor CNS changes:

dizziness, drowsiness,

hallucinations, euphoria,

LOC, pupil reactions

- Monitor allergic

reactions: rash, urticaria

Administ

er when pain is

 beginningto return;

determinedosageinterval by

 patient

response;continuous dosing

of medicatio

n is moreeffective

thangiving prn

Increased:

amylase

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more than 30 mg

q4day Resp: Respiratory

depression, respiratory

arrest, apnea 

- Assess respiratory

dysfunction: depression,

character, rate, rhythm;

notify prescriber if 

respirations are <10/min

MedicationTrade/Generic

Classification

Patient Dose

Dose Limits

Uses/Purpose

Mode of Action

Side Effects

Adverse Reactions

Contraindications

 Nursing Implications

Time(s) to be given

Pre/postadmin

Labs/VS toconsider 

Hydromorphone/

Dilaudid

 F unc.class.: Antitussive,

opioid analgesicagonist

C hem.class.: Phenanthrenederivative, guaifenesin

Antitussive Adult: PO 1 mgq3-4hr prn

Child 6-12

yr: PO 0.5 mgq3-4hr 

Geriatric: PO 1-2 mg q4-6hr 

Availableforms: Inj 1, 2,

4, 10 mg/ml;tabs 2, 4, 8 mg;

oral sol 5 mg/5

ml; supp 3 mg

Action: Inhibits

ascending pain pathways in CNS,

increases painthreshold, alters

 pain perception

Therapeutic

outcome: Decreased cough,decreased pain

Uses: As an

antitussive tosuppress cough;

moderate to severe

 pain

CNS: Dizziness,

drowsiness, sedation,confusion, headache,

euphoria, moodchanges, seizures 

CV:  Hy potension,

brad  ycardia, palpitations,

change in B/P, tachycardia, peripheral vasodilatation

EENT: Miosis, diplopia, blurred vision, tinnitus

GI: Nausea, constipation,

vomiting, anorexia, dry

mouth, cramps, paralyticileus

GU: Increased urinaryoutput, dysuria, urinary

retention

INTEG: Urticaria, rash,

flushing, bruising,diaphoresis, pruritus

Contraindications: 

Hypersensitivity

Nursing

Implications

- Assess pain control,

sedation by scoring on

0-10 scale; around-the-clock dosing is best for 

 pain control 

- Monitor VS after 

 parenteral route; notemuscle rigidity;

 product history, renal,liver function tests;

respiratory dysfunction:

respiratory depression,character, rate, rhythm;notify prescriber if 

respirations are

<10/min 

- Monitor CNSchanges: dizziness,

drowsiness,hallucinations,euphoria, LOC, pupil

Give when

 pain is beginning

to return;determine

dosageinterval by

 patient

response;continuous dosing

of medicatio

n is moreeffective

given prn;

explainanalgesiceffect

Increased:

amylase

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Human regular Adult: SUBCUT ½-1hr before meals

Insulin, isophane

suspension Adult: SUBCUTdosage individualized

 by blood, urineglucose; usual dose 7-26 units; may increase by 2-10 units/day if needed

Insulin detemir Adult: SUBCUT 1 or 2 times/day; if 1 time,give with eveningmeal

Insulin glargine Adult and child 6yr: SUBCUT 10

internationalunits/day, range 2-100international units/day

sulfonylureas in

children >3 yr  acetone breath, polyuria,

fatigue, polydipsia,

flushed, dry skin, lethargy

INSULIN Table:

Type Onset Peak Duration

Rapidand Short-Acting 

Insulin glulisine (Apidra) 15 min 1 hour 2-3 hours

Insulin lispro (Humalog) 15 min 1 hour 4 hours

Insulin aspart (NovoLog) 30 min 1-3 hours 3-5 hours

Regular insulin*

30 min-1 hour 2-4 hours 5-7 hours

Intermediate-Acting 

Isophane insulin suspension (NPH insulin, Humulin N) 3-4 hours 6-12 hours 18-28 hours

Insulin zinc suspension (Lente insulin) 1-3 hours 8-12 hours 36 hoursLong-Acting 

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Type Onset Peak Duration

Extended insulin zinc suspension (Ultralente) 4-6 hours 18-24 hours 36 hours

Insulin glargine (Lantus)

1-5 hours Plateau 24 hours

Insulin detemir (Levemir) 3-4 hours ³Peakless´ 24 hours