mendel s work - mrs. weisenbach's biology cabin

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Page 1: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel’s Work

Page 2: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Early Ideas

�  People used to believe that offspring were a blend of genetic material from both parents.

�  The genetic material mixed or blended like colors of paint.

�  This is not the case because over many generations, populations would eventually look alike.

�  Blending inheritance cannot explain why some traits skip a generation.

Page 3: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Gregor Mendel

� Gregor Mendel: “The Father of Genetics” ÷ Austrian priest/monk ÷ 1822 to 1884

¡ Pea plants had different physical characteristics, or traits. ÷ Ex: Tall plants and short plants.

Green seeds and yellow seeds.

Page 4: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Gregor Mendel

�  He also noticed that the characteristics of the pea plants resembled those of the parent plants. This passing of traits from parents to offspring is called heredity.

�  Mendel worked with thousands of pea plants to

understand the process of heredity. �  Mendel’s work formed the foundation of genetics,

the scientific study of heredity.

Page 5: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Why Pea Plants?

�  They are self-pollinating. ¡  They have both male and female parts ¡  This means that the pollen from one

flower lands on the pistil of the same flower.

�  He developed a method to cross-pollinate ¡  He removed the pollen from one plant

and brushed it onto a second plant.

Page 6: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel’s Experiments

�  Mendel started his experiment with purebred plants.

�  Purebred is the offspring of many generations that have the same trait.

EX: A purebred short plants always produce short offspring.

Page 7: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel’s First Experiment

�  Mendel first crossed a purebred short plant with a purebred tall plant. He called these two plants the parental (P) generation.

�  He called the offspring the first filial generation or the (F1) generation.

�  To Mendel’s surprise, all the offspring were tall.

Page 8: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel’s Second Experiment

�  Mendel then took the offspring, the F1 generation, and crossed them.

�  These results also surprised Mendel.

�  The offspring in the second filial generation or (F2) were a mix of tall and short plants.

�  He found that 75% were tall and 25% were short.

Page 9: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel concluded

�  Mendel believed that individual factors or sets of genetic “information” must control the inheritance of traits. ¡ The factors that control traits exists in pairs. ¡ Each parent (mother & father) contributes 1 of

the factors for each trait. ¡ One factor in the pair can mask or hide the other

factor.

Page 10: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Genes

�  Gene: the factors that control a particular trait. ¡  Ex.) eye color, height, hair color, nose shape, etc.

Page 11: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Allele

�  Allele: the different forms of a gene ¡  Ex.) eye color: brown, blue, green

Page 12: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Genes and Alleles

�  A gene is a section of DNA that has information about a trait in an organism.

�  Each form of a gene with different information is called an allele.

Page 13: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Video Where do your genes come from? Video Link! Genetics 101 Part III, Where do your genes come from?

http://www.youtube.com/watch?v=Om0ZvtBmSAs

Copyright© 2010 Ryan P. Murphy

Page 14: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Dominant & Recessive

�  Dominant Allele ¡  A genetic factor that

blocks, or masks, another genetic factor

¡  Shown with capital letter ¡  When the dominant allele

is present, the trait is always expressed.

÷ EX: B, X, W, R, Y

�  Recessive Allele ¡  A genetic factor that is

hidden by the presence of a dominant factor

¡  Shown with lower case letter

¡  The trait will only be expressed when both alleles are recessive.

÷ EX: b, x, w, r, y

Page 15: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant

Copyright© 2010 Ryan P. Murphy

Page 16: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant �  t = Recessive

Copyright© 2010 Ryan P. Murphy

Page 17: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant �  t = Recessive �  TT = Two dominant

Copyright© 2010 Ryan P. Murphy

Page 18: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant �  t = Recessive �  TT = Two dominant �  tt = Two recessive

Copyright© 2010 Ryan P. Murphy

Page 19: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant �  t = Recessive �  TT = Two dominant �  tt = Two recessive �  Tt = One dominant, one recessive

Copyright© 2010 Ryan P. Murphy

Page 20: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant �  t = Recessive �  TT = Two dominant (purebred) �  tt = Two recessive (purebred) �  Tt = One dominant, one recessive (hybrid)

Copyright© 2010 Ryan P. Murphy

Page 21: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Copyright© 2010 Ryan P. Murphy

•  T = Dominant •  t = Recessive •  TT = Two dominant (purebred) •  tt = Two recessive (purebred) •  Tt = One dominant, one recessive

(hybrid)

Page 22: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant �  t = Recessive �  TT = Two dominant �  tt = Two recessive �  Tt = One dominant, one recessive

Copyright© 2010 Ryan P. Murphy

Page 23: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  T = Dominant �  t = Recessive �  TT = Two dominant �  tt = Two recessive �  Tt = One dominant, one recessive

Copyright© 2010 Ryan P. Murphy

Page 24: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 25: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 26: Mendel s Work - Mrs. Weisenbach's Biology Cabin
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Page 31: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 32: Mendel s Work - Mrs. Weisenbach's Biology Cabin
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Page 34: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 35: Mendel s Work - Mrs. Weisenbach's Biology Cabin
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Page 41: Mendel s Work - Mrs. Weisenbach's Biology Cabin
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Understanding Mendel’s Crosses

�  Mendel’s P generation plants were purebred, meaning they had two of the same alleles. ¡  (TT) = “purebred tall” (tt)= “purebred short”

�  The F1 offspring received one allele from each parent making the allele combination: Tt.

�  These plants were hybrid, an organism that has both the dominant and the recessive allele for a trait. ¡  (Tt) = “hybrid tall”

Page 43: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel also tested many other traits

Page 44: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel’s breeding experiments

�  Ex.) Seed color

Parents (P)

First generation (F1)

Page 45: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendels’ breeding experiments

�  Ex. Continued.) Seed color

�  1st generation(F1)

�  2nd generation (F2)

Page 46: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Mendel’s Contribution

�  Many scientists thought that Mendel’s explanation of heredity was oversimplified.

�  His work was forgotten for

34 years. �  Years later, three other

scientists confirmed his findings and he became known as: “The Father of Genetics”

Page 47: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Video Link! Genetics 101 Part IV Phenotypes http://www.youtube.com/watch?v=jHWJqzlHl3w

Page 48: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Genotypes and Phenotypes

�  An organism’s phenotype is its physical appearance or its visible traits.

�  Ex: Phenotype = “short” “tall” “green” “yellow” �  An organism’s genotype is its genetic make-up or

allele combination. �  Ex: Genotype = “TT, Tt, tt, GG, Gg, gg

Page 49: Mendel s Work - Mrs. Weisenbach's Biology Cabin

�  What are some of your phenotypes?

Copyright© 2010 Ryan P. Murphy

Page 50: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Let’s practice . . .

�  Phenotype �  Phenotype �  Genotype �  Phenotype �  Phenotype �  Genotype �  Genotype

�  Yellow �  Wrinkled �  XX �  Tall �  White �  yy �  Purebred

Page 51: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 52: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 53: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Homozygous and Heterozygous

Scientists use two more methods to describe an organisms genotype. �  Homozygous - an organism that has two identical

alleles for a trait is said to be homozygous for that trait.

Example: TT or tt (purebred) �  Heterozygous - an organism that has different alleles

for a trait is said to be heterozygous for that trait. Example: Tt (hybrid)

Page 54: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Let’s practice . . .

1.  BB 2.  Rr 3.  Aa 4.  AA 5.  tt 6.  Bb 7.  ff 8.  YY 9.  hybrid

1.  Homozygous 2.  Heterozygous 3.  Heterozygous 4.  Homozygous 5.  Homozygous 6.  Heterozygous 7.  Homozygous 8.  Homozygous 9.  Heterozygous

Page 55: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  a  gene?  

A.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    B.)  An  organisms  physical  appearance  or  visible  traits.    C.)  Factors  that  control  traits.  D.)  When  the  female  contributes  one  factor,  while  the  male  contributes  the  other.  

Copyright © 2010 Ryan P. Murphy

Page 56: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  a  gene?  

A.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    B.)  An  organisms  physical  appearance  or  visible  traits.    C.)  Factors  that  control  traits.  D.)  When  the  female  contributes  one  factor,  while  the  male  contributes  the  other.  

Copyright © 2010 Ryan P. Murphy

Page 57: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  a  gene?  

A.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    B.)  An  organisms  physical  appearance  or  visible  traits.    C.)  Factors  that  control  traits.  D.)  When  the  female  contributes  one  factor,  while  the  male  contributes  the  other.  

Copyright © 2010 Ryan P. Murphy

Page 58: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 59: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  heredity?  

A.)  When  the  female  contributes  one  factor,  while  the  male  contributes  the  other.  B.)  An  organisms  physical  appearance  or  visible  traits.    C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  Factors  that  control  traits.  E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 60: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  heredity?  

A.)  When  the  female  contributes  one  factor,  while  the  male  contributes  the  other.  B.)  An  organisms  physical  appearance  or  visible  traits.    C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  Factors  that  control  traits.  E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 61: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  heredity?  

A.)  When  the  female  contributes  one  factor,  while  the  male  contributes  the  other.  B.)  An  organisms  physical  appearance  or  visible  traits.    C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  Factors  that  control  traits.  E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 62: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 63: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  Mendel’s  Law  of  SegregaJon?  

A.)  An  organisms  physical  appearance  or  visible  traits.    B.)  When  allele  pairs  separate  during  gamete  formaJon,  and  randomly  unite  at  ferJlizaJon.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  An  organisms  geneJc  makeup,  or  allele  combinaJons.  E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 64: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Answer  is…  Which  le2er  below  best  describes  Mendel’s  Law  of  SegregaJon?  

A.)  An  organisms  physical  appearance  or  visible  traits.    B.)  When  allele  pairs  separate  during  gamete  formaJon,  and  randomly  unite  at  ferJlizaJon.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  An  organisms  geneJc  makeup,  or  allele  combinaJons.  E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 65: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review    Answer  is…  Which  le2er  below  best  describes  Mendel’s  Law  of  SegregaJon?  

A.)  An  organisms  physical  appearance  or  visible  traits.    B.)  When  allele  pairs  separate  during  gamete  formaJon,  and  randomly  unite  at  ferJlizaJon.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  An  organisms  geneJc  makeup,  or  allele  combinaJons.  E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 66: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review      Answer  is…  Which  le2er  below  best  describes  Mendel’s  Law  of  SegregaJon?  

A.)  An  organisms  physical  appearance  or  visible  traits.    B.)  When  allele  pairs  separate  during  gamete  formaJon,  and  randomly  unite  at  ferJlizaJon.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  An  organisms  geneJc  makeup,  or  allele  combinaJons.  – E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 67: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review    Answer  is…  Which  le2er  below  best  describes  Mendel’s  Law  of  SegregaJon?  

A.)  An  organisms  physical  appearance  or  visible  traits.    B.)  When  allele  pairs  separate  during  gamete  formaJon,  and  randomly  unite  at  ferJlizaJon.  C.)  When  traits  are  passed  from  parents  to  offspring.  – D.)  An  organisms  geneJc  makeup,  or  allele  combinaJons.  

– E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 68: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review    Answer  is…  Which  le2er  below  best  describes  Mendel’s  Law  of  SegregaJon?  

A.)  An  organisms  physical  appearance  or  visible  traits.    B.)  When  allele  pairs  separate  during  gamete  formaJon,  and  randomly  unite  at  ferJlizaJon.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  An  organisms  geneJc  makeup,  or  allele  combinaJons.  – E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 69: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review    Answer  is…  Which  le2er  below  best  describes  Mendel’s  Law  of  SegregaJon?  

A.)  An  organisms  physical  appearance  or  visible  traits.    B.)  When  allele  pairs  separate  during  gamete  formaJon,  and  randomly  unite  at  ferJlizaJon.  C.)  When  traits  are  passed  from  parents  to  offspring.  – D.)  An  organisms  geneJc  makeup,  or  allele  combinaJons.  

– E.)  Allele  that  is  covered  up  when  the  dominant  allele  is  with  it.    

Copyright © 2010 Ryan P. Murphy

Page 70: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 71: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  an  allele?  

A.)  An  organisms  geneJc  make  up.  B.)  An  organisms  physical  appearance  or  visible  traits.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  The  different  forms  of  a  gene.  E.)  Alleles  do  not  exist  in  nature.    

Copyright © 2010 Ryan P. Murphy

Page 72: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  an  allele?  

A.)  An  organisms  geneJc  make  up.  B.)  An  organisms  physical  appearance  or  visible  traits.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  The  different  forms  of  a  gene.  E.)  Alleles  do  not  exist  in  nature.    

Copyright © 2010 Ryan P. Murphy

Page 73: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  le2er  below  best  describes  an  allele?  

A.)  An  organisms  geneJc  make  up.  B.)  An  organisms  physical  appearance  or  visible  traits.  C.)  When  traits  are  passed  from  parents  to  offspring.  D.)  The  different  forms  of  a  gene.  E.)  Alleles  do  not  exist  in  nature.    

Copyright © 2010 Ryan P. Murphy

Page 74: Mendel s Work - Mrs. Weisenbach's Biology Cabin
Page 75: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  two  le2ers  below  best  describes  an  organisms  phenotype  and  genotype?  

A.)  When  traits  are  passed  from  parents  to  offspring.    B.)  An  organisms  geneJc  make  up.  C.)  An  organisms  physical  appearance  or  visible  traits.  D.)  The  different  forms  of  a  gene.  E.)  When  an  organism  cannot  pass  on  geneJc  informaJon.    

Copyright © 2010 Ryan P. Murphy

Page 76: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  two  le2ers  below  best  describes  an  organisms  phenotype  and  genotype?  

A.)  When  traits  are  passed  from  parents  to  offspring.    B.)  An  organisms  geneJc  make  up.  C.)  An  organisms  physical  appearance  or  visible  traits.  D.)  The  different  forms  of  a  gene.  E.)  When  an  organism  cannot  pass  on  geneJc  informaJon.    

Copyright © 2010 Ryan P. Murphy

Page 77: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  two  le2ers  below  best  describes  an  organisms  phenotype  and  genotype?  

A.)  When  traits  are  passed  from  parents  to  offspring.    B.)  An  organisms  geneJc  make  up.  C.)  An  organisms  physical  appearance  or  visible  traits.  D.)  The  different  forms  of  a  gene.  E.)  When  an  organism  cannot  pass  on  geneJc  informaJon.    

Copyright © 2010 Ryan P. Murphy

Page 78: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  two  le2ers  below  best  describes  an  organisms  phenotype  and  genotype?  

A.)  When  traits  are  passed  from  parents  to  offspring.    B.)  An  organisms  geneJc  make  up.  C.)  An  organisms  physical  appearance  or  visible  traits.  D.)  The  different  forms  of  a  gene.  E.)  When  an  organism  cannot  pass  on  geneJc  informaJon.    

Copyright © 2010 Ryan P. Murphy

Page 79: Mendel s Work - Mrs. Weisenbach's Biology Cabin

Vocabulary  Review  Which  two  le2ers  below  best  describes  an  organisms  phenotype  and  genotype?  

A.)  When  traits  are  passed  from  parents  to  offspring.    B.)  An  organisms  geneJc  make  up.  C.)  An  organisms  physical  appearance  or  visible  traits.  D.)  The  different  forms  of  a  gene.  E.)  When  an  organism  cannot  pass  on  geneJc  informaJon.    

Copyright © 2010 Ryan P. Murphy