motor system 1
TRANSCRIPT
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MOTOR SYSTEM IMOTOR SYSTEM I
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idea
Cortical
associationarea
Basal
ganglia
Lateral
cerebellum
Premotor, supplementary
motor and motor cortex
Intermediate
cerebellum
musclesBrain stem
Plan Execute
Spinal cord
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NEURAL AREAS THAT CONTROL
MOTOR FUNCTION
A. CEREBRAL CORTEX
B. BASAL GANGLIA
C. CEREBELLUM
D. BRAINSTEM
E. SPINAL CORD
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I. CEREBRAL CORTEX
MOTOR CORTEXanterior to the central sulcus occupies
approximately the posterior 1/3 of the
frontallobeTHREE SUB AREAS
A. PRIMARY MOTOR AREA
B. PREMOTOR AREAC. SUPPLEMENTARY MOTOR AREA
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A. Primary MotorArea
CorticalEff
erent Zones orMotor Homunculus
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Posterior Parietal
Cortex
(Somatic Sensory
area I and II)
producedalso motor
responses
projects to the premotor
areaand supplementary
area
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B. PremotorArea
receives a major input from the posterior
parietal cortex and its output influences
chiefly medialdescending pathway.
concerned with setting posture at the
start ofa planned complex movement.
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C. Supplementary MotorArea
cause complex contraction that is usually
bilateral
needs stronger electrical stimulus to cause
contractionbelieved to be concerned with mental
rehearsal ofa planned movement.
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Some other specialized corticalareas that
control motor function:
a) Brocas area
b) Voluntary Eye Movement Field /Frontal Eye Field
c) Head Rotation Area
d) Area for Hand Skills
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II. BASAL GANGLIAComponents:
a) caudate nucleusstriate body
b) putamen
lentiform nucleus
c) globus pallidus
Functionally related nuclei;
a) subthalamic nucleus (diencephalons)
b) substancianigra (midbrain)c) ventralanterior (VA)and ventrallateral (VL)
thalamic nuclei
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cortex
Striatum
(acetylcholine)
Substancia nigra
Pars compacta
thalamus
Supplementary motor area
Globus pallidus Substancia nigraInternal segment pars reticulata
Globus palliodus
External segment
Subthalamic nucleus
GABA/substance P
dopamine
glutamateGABA/enkephalin
glutamateGABA glutamate
glutamate
GABA
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Two Important Pathways
A) Direct Pathwayenhance motoractivity
controls rapid motoractivity
decreasedactivity will cause hypokinetic behavior.
B) Indirect Pathwayreduce motoractivity
controls slow motoractivity
decreasedactivity will cause hyperkineticbehavior
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Two General Types ofDisordersA. HYPERKINETIC BEHAVIOR
a) Choreacaused byalesion in the striate body.
characterized by rapid, involuntarydancing movements.
b) Ballismus (Hemiballismus)
caused byalesion in the subthalamic nucleus.
characterized by involuntaryand violent flailing movementsof the limbs.
c) Athetosis
caused byalesion in the lenticularnucleus.
characterized bya slow, writhing movement of wormlikecharacter that appears chiefly in fingers and wrist.
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B. HYPOKINETIC BEHAVIOR
a) Akinesia
difficulty in initiating movement and
decreased spontaneous movement
b) Bradykinesia
slowness in initiating movement
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III. CEREBELLUM
helps regulate movements and postureandalso involved in some forms of motor
learning.
its major role is for motor coordination
(rate, range, force anddirection of the
movement)
deep cerebellarnuclei dentate nucleus
emboliform
globose
fastigialnuclei
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Anatomic Division
A. Anteriordivision
B. Posteriordivision
C. Flocculonodulardivision
FUNCTIONAL DIVISION
A. Vestibulocerebellum (Archicerebellum)
B. Spinocerebellum (Paleocerebellum)
C. Cerebrocerebellum / Corticocerebellum(Neocerebellum)
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A. Vestibulocerebellum (Archicerebellum)
corresponds primarily to theflocculonodularlobe.
dominated by vestibular input.
regulates eye movement, stance andgait. (equilibrium andlearning induced
changes in VOR*
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B. Spinocerebellum (Paleocerebellum)corresponds primarily to the intermediate
portion.
receives proprioceptive and spinal cord
input.
regulates truncaland proximallimbs
movements (maintenance of posture)
it smoothes and coordinates movementsthat are ongoing
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C. Corticocerebellum or Cerebrocerebllum
(Neocerebellum)
corresponds to the lateral portion.
receives indirect input from the cerebrum
by way pontine nuclei.concerned with motor planningand
programming
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Motor Dysfunctions in Cerebellar
Diseaseincoordination, malequilibrium and
problems with muscle tone.
AtaxiaDysmetria / Pastpointing
Dysdiadochokinesia/ Adiadochokinesia
Domposition of movement
DysarthriaIntension tremors
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Malequilibrium
Disturbances in muscle tone
Astasia - loss of muscle endurance
Asthenia - loss of muscle strength
Atonia/Hypotonia - absent /
diminished muscle tone
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IV. BRAINSTEM
composed of midbrain, pons and medulla.primarily concerned with the control ofaxialand
proximal musculature (antigravity muscles)
Brainstem Pathwaysreticulospinal pathway
vestibulospinal pathway Medialdescending
tectospinal pathway Pathway
rubrospinal pathway - Lateral DescendingPathway
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V. SPINAL CORD
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Cells in the anterior horn
motorneuron
innervates extrafusal muscle fibers.
motorneuron
innervates intrafusal muscle fibers
interneurons
most abundant
inhibitory or excitatory
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DESCENDING PATHWAYS
A) Corticobulbar Tract
B) Corticospinal Tract
most important output pathway from the
cerebral cortex.
origin:
30% - primary motorarea
30% - premotorarea40% - posterior parietalarea
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Lateral Corticospinal Tract
constitute 80% of the fibers.
fibers cross at the midline of the medullary
pyramid.
occupies the lateral portion of the spinalcord.
concerned with the control ofdistal
musculature (hands and fingers).
mediate fine and skilled movements.
includes rubrospinal tract.
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Medial / Anterior / Ventral Corticospinal
Tract
constitute 20% of the fibers.fibers do not cross at the midline of the medullary
pyramid.
occupies the ventral (anterior)and medial portionof the spinal cord.
concerned with the control ofaxialand proximalmusculature (trunk and proximallimbs)
projection fibers of medial system are mostlycoming from the premotor cortex.
mediate posturaladjustments andgross
movementsincludes reticulospinal, vestibulospinaland
tectospinal