MMC, VICC & TSU: Partners in Eliminating Cancer Health Disparities

Meharry and Vanderbilt become one of the

first Cancer Partnerships supported by the

NCI U54 grant mechanism

MVTCP continues to grow. The partnership

has submitted a competitive renewal and will

expand training to high school students.

TSU becomes a full partner and the MVTCP

becomes the second Triad in the PACHE.

TSU brings new investigators and

undergraduate students.

Tennessee State (TSU) joins the MVCP as a

collaborator, expanding the partnerships

research into Community Engaged Research

Meharry and Vanderbilt form a partnership in

response to a supplement to the CCSG grant.

Our Cancer Partnership has matured and developed successful

collaborative interactions based on excellence, true reciprocity, and

mutual benefit. As a triad, we aim to amplify the cancer research

capabilities in the greater Nashville community, improve outcomes in the

diagnosis and treatment of cancer in minority and underserved

communities, minimize measurable disparities among minority

populations, and fortify collaborations among the partners. During the past

5 years, we have made significant progress toward achieving our mission

through: 1) recruiting 6 new faculty members; 2) training 7 PhD and MPH

candidates at MMC and TSU; 3) training 4 oncology fellows at MMC/

VICC; 4) providing summer cancer research experience to 18

undergraduates at TSU and 22 medical students at MMC and VICC; and

5) increasing clinical trials access. Our clinical trials core accrued 350

patients (57% African American) and increased the number of open

clinical trials in both cancer treatment and control studies (50% over two

years). Our program evaluation structure includes the monitoring by the

Internal Advisory Committee, the Program Steering Committee, and the

As we look ahead, we plan to:

1. Fund state-of-the-art research projects to increase and stabilize the

competitive cancer research capability of MMC and TSU;

2. Increase the cancer disparities research portfolio at VICC;

3. Expand cancer research education program to include high school

students;

4. Implement a hybrid outcomes-logic-model and a pure outcomes-based

process to evaluate the Partnership’s progress;

5. Enhance clinical trials access for minority populations served by

Nashville General Hospital (NGH)/MMC.

Lourdes Estrada, Ph.D.1*

, Ketia Barnes, B.S.2*

, David E. Danner, J.D.3, W. Wayne Green, B.S.

2, Samuel E. Adunyah, Ph.D.

2,

Baqar A. Husaini, Ph.D.3, Philip E. Lammers, M.D.

2, Harold L. Moses, M.D.

1, Ann Richmond, Ph.D.

1, Margaret Whalen, Ph.D.

3

*Presenting Co-authors; 1Vanderbilt Ingram Cancer Center, Nashville, TN;

2Meharry Medical College, Nashville, TN;

3Tennessee State University, Nashville, TN

Acknowledgments

Education & Training

Future Directions

Clinical Trials Community Outreach Introduction

Partnership History

Activities

Engagement with populations affected by cancer health disparities through Community Advisory Board (CAB), Teen and Parent (TAP) Committee, Cancer Survivorship Committee, listserv and outreach to underserved communities.

Provision of tangible support to MVTCP-funded and emerging projects (e.g., expert consultation, recruitment, protocol development & review), community organizations and coalitions, and the NCI National Outreach Network in cancer disparities efforts.

Mentoring students and trainees in Community Engaged Research and culturally-appropriate outreach strategies.

Administrative supplement to expand evaluation of HPV vaccine social marketing intervention

Hosting of two radio health programs reaching African American and Hispanic audiences, providing 100 hours of health information programming and cancer researcher guest interviews each year.

Accomplishments

Awarded NCORP grant partnership with Memphis Baptist Healthcare System

Successful Alliance Cooperative Group Site Audit and WFU Site Audit

Nashville General Hospital was awarded Commission on Cancer 3-Year Accreditation with a Commendation for Clinical Trials Program and Accruals

Hired a 2nd medical oncologist, Dr. Robin Jacob from Howard University and a surgical oncologist, Dr. Sandeep Anantha from Michigan

This material is based upon work supported by the National Cancer Institute PACHE program grant numbers 5U54CA163069 (MMC), 5U54CA163072 (VICC), and 5U54CA163066 (TSU).

Research Activity

Recruitment Basic Science Population Science Clinical Science

Anil Shanker, MS,

PhD (MMC)

Rebecca Selove, MPH,

PhD (TSU)

Philip Lammers, MD,

MSCI (MMC)

Jamaine Davis, PhD

(MMC)

Hilary Tindle, MD, MPH

(VICC)

Sandeep Anantha, MD

(MMC)

0

50

100

150

200

250

300

2011 2012 2013 2014 2015 2016 CancerControlStudies

CancerTreatment

Trials

MVTCP Clinical Trials Core Enrollment to Clinical Research 2011-2016

Caucasian African-American Hispanic Other

2011 - 2015

Full Projects: Supported a total of four (4) full projects - two for three years on breast cancer and prostate cancer and two for two years on cancer survivorship and lung cancer .

Pilot Projects: Supported a total of two (2) pilot projects - one for three years on HPV vaccine and the other for two years on breast cancer.

Shared Resource Cores: Support four (4) Shared Resource Cores:

Biostatistics Core

Translational Pathology Core

Clinical Trials Core

Community Outreach Core

Grants: Awarded over 20 grants including 3 R01s, 2 SC1s, and 2 R21s

Publications: 150+ peer-reviewed publications

Meharry (MMC) - Vanderbilt (VICC) - Tennessee State (TSU) Cancer Partnership

Drs. Pam Hull (l) and Lourdes Estrada from VU on

Progress & Wellbeing (Progreso y Bienestar) on La

Nueva Activa 1240 AM

Training Opportunities

Undergraduates: Summer Research Experience; Introduction to Cancer

Biology Course, Mentored Behavioral Science Training in Cancer

Disparities

Masters of Public Health Students: Summer Research Experience;

Graduate Internship with Community Outreach Core

Doctoral Students: Pre-doctoral training support

Medical Students: Summer Research Experience

Postgraduates: Oncology Fellowship with Clinical Trials Core