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Pagina 1 - Curriculum vitae di [ DE BONIS, Michele ] CUR RI CU L U M V I T AE PERSONAL INFORMATION Name: MICHELE DE BONIS, MD, FESC, FAHA Place of birth: Pietragalla (Potenza) - Italy Date of birth: July 29th, 1968 Citizenship: Italian. Marital status: married Languages spoken: Italian, English, French. Work address: “Vita e Salute” San Raffaele University Department of Cardiac Surgery San Raffaele Hospital Via Olgettina 60, 20132 Milan, Italy Phone: +39-02-2643 7118 Fax: +39-02-2643 7125 Email: [email protected] PROFESSIONAL EXPERIENCE 2017-present 2017-present 2016-present 2017-present 2017-present 2017-present Chief of Cardiac Surgery, Innovation and Research, San Raffaele University Hospital, Via Olgettina 60, 20132 Milan, Italy Director Training School in Cardiac Surgery, “Vita e Salute” San Raffaele University Medical School, Milan, Italy Associate Professor of Cardiac Surgery, “Vita e Salute” San Raffaele University Medical School, Milan, Italy Visiting Professor of Cardiac Surgery, Plymouth NHS Trust, Plymouth, United Kingdom Visiting Professor of Cardiac Surgery, Cardiovascular Research Unit, Faculty of Health Sciences, Cape Town University, South Africa Chairman of the Task Force on Mitral and Tricuspid Surgery of the European Association for Cardiothoracic Surgery

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Page 1: Name: Place of birth Date of birth Citizenship Marital status ......Languages spoken: Italian, English, French. Work address: “Vita e Salute” San Raffaele University Department

Pagina 1 - Curriculum vitae di [ DE BONIS, Michele ]

CUR RI CU L U M V I T AE

PERSONAL INFORMATION

Name: MICHELE DE BONIS, MD, FESC, FAHA

Place of birth: Pietragalla (Potenza) - Italy

Date of birth: July 29th, 1968

Citizenship: Italian.

Marital status: married

Languages spoken: Italian, English, French. Work address: “Vita e Salute” San Raffaele University

Department of Cardiac Surgery

San Raffaele Hospital

Via Olgettina 60, 20132 Milan, Italy

Phone: +39-02-2643 7118

Fax: +39-02-2643 7125

Email: [email protected]

PROFESSIONAL EXPERIENCE

• 2017-present

• 2017-present

• 2016-present

• 2017-present

• 2017-present

• 2017-present

Chief of Cardiac Surgery, Innovation and Research, San Raffaele University Hospital, Via Olgettina 60, 20132 Milan, Italy

Director Training School in Cardiac Surgery, “Vita e Salute” San Raffaele University Medical School, Milan, Italy

Associate Professor of Cardiac Surgery, “Vita e Salute” San Raffaele University Medical School, Milan, Italy

Visiting Professor of Cardiac Surgery, Plymouth NHS Trust, Plymouth, United Kingdom

Visiting Professor of Cardiac Surgery, Cardiovascular Research Unit, Faculty of Health Sciences, Cape Town University, South Africa

Chairman of the Task Force on Mitral and Tricuspid Surgery of the European Association for Cardiothoracic Surgery

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Pagina 2 - Curriculum vitae di [ DE BONIS, Michele ]

• 2017-present

• 2015-present

• 2009-present

• 2008-2016

• 2007-2016

• 2007- 2008

• 2000-2006

Contract Professor at Politecnico of Milano as lecturer and coordinator of the PhD course “3D printing and modeling: towards patient’s tailored treatment and surgical planning”within the Bioengineering PhD Program 2017-2018

“European Liaison” of the Leadership Committee Commission of Council on Cardiovascular Surgery and Anesthesia of the American Heart Association

Head of the “Heart failure surgery and Mechanical Circulatory Support Programme” of the Department of Cardiac Surgery, San Raffaele University Hospital, Milan, Italy

Contract Professor of Cardiac Surgery at “Vita e Salute” San Raffaele University Medical School, Milan, Italy. Courses and lectures on: - "Mechanical circulatory support"

- "Surgical options for heart failure"

Contract Professor of Cardiac Surgery at the training School in Cardiac Surgery of “Vita e Salute” San Raffaele University Medical School, Milan, Italy.

Contract Professor of Cardiac Surgery at the Nursing School of “Vita e Salute” San Raffaele University Medical School, Milan, Italy.

Senior Staff Cardiac Surgeon (Research and clinical activity)

Department of Cardiac Surgery San Raffaele University Hospital Milan, Italy

Staff Cardiac Surgeon (Research and clinical activity)

Department of Cardiac Surgery

San Raffaele University Hospital Milan, Italy

Surgical experience

More than 5000 major cardiac surgery operations of which over 2500 performed as first operator. Mitral and tricuspid repair, minimally invasive valve surgery and mechanical circulatory support (LVAD/BiVAD/TAH) represent areas of specific interest and expertise.

• Clinical responsibilities From 2017 he is the Director of Cardiac surgery, Innovation and Research at San Raffaele University Hospital, Milan, Italy.

Since 2009 he has been responsible for the “Heart failure surgery Unit and Mechanical Circulatory Support Programme” of the Department of Cardiac Surgery, San Raffaele University Hospital, Milan, Italy. After a training period spent as a Fellow on mechanical support systems at the German Heart Institute in Berlin, he started (in close collaboration with the Cardiac Surgery Intensive Care Unit), a comprehensive program of mechanical circulatory support at San Raffaele Hospital in Milan. This program is currently

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consolidated and includes the use of paracorporeal systems (ECMO venous- arterial and veno-venous, LVAD/RVAD/BiVAD type Levitronix-CentriMag), partially implantable systems (Incor, Jarvik, HeartMate II and III, Heartware) and total artificial heart (CardioWest). Currently approximately 100 patients/year are treated with an ECMO system in our Unit and more about 100 70 patients received an LVAD as destination therapy. The experience in this field is confirmed by the role of "proctor" for implantation of the HeartMate II and III left ventricular assist system (Thoratec) covered from the year 2015. He has obtained the following implantation certifications:

• SynCardia

Total artificial heart phase I training Germany 24th February 2012

• HeartMate III Masterclass

National Research Cardiac Surgery Center Astana, Kazakhstan June 30th-July 1st 2015

National and international executive offices

Over the years he has served in different roles the European Society of Cardiology (ESC), the European Association for Cardiothoracic Surgery (EACTS), the American Heart Association (AHA), the Italian Society of Cardiac Surgery (SICCH) and the Heart Valve Society (HVS). In particular he has been

➢ Chairman of the Working Group on Cardiovascular Surgery of the European Society of Cardiology.

➢ Member of the “Acquired Cardiac Disease Domain” of the European

Association for Cardiothoracic Surgery

➢ Coordinator of the “ Committee for Guidelines and Position Papers" and member of the “Committee for the relationships with the European Association for Cardiothoracic Surgery” of the Italian Society of Cardiac Surgery

➢ "Coordinator" (liaison) for Europe of the Leadership Committee of the

Commission of the Council on Cardiovascular Surgery and Anesthesia of the American Heart Association.

➢ As a member of the "Congress Programme Committes" (CPC) of the

ESC, EACTS and HVS he has systematically participated in the organization of the related annual meeting scientific programs.

Guidelines of the European Society of Cardiology and Cardiac Surgery He has been a member of "The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)” (version 2012 and 2017) and of the Task Force of the ESC Guidelines on “Cardiovascular disease during

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Pagina 4 - Curriculum vitae di [ DE BONIS, Michele ]

pregnancy”(version 2018). He has participated in drafting the following European guidelines on valvular disease, infective endocarditis, pregnancy, dual anti- platelet therapy:

1) Authors/Task Force Members, Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Barón-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Iung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M; ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S; Document Reviewers:, Popescu BA, Von Segesser L, Badano LP, Bunc M, Claeys MJ, Drinkovic N, Filippatos G, Habib G, Kappetein AP, Kassab R, Lip GY, Moat N, Nickenig G, Otto CM, Pepper J, Piazza N, Pieper PG, Rosenhek R, Shuka N, Schwammenthal E, Schwitter J, Mas PT, Trindade PT, Walther T. Guidelines on the management of valvular heart disease (version 2012): The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2012 Oct;33(19):2451-96

2) 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC)Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Authors/Task Force Members, Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos- Hesselink J, Snygg-Martin U, Thuny F, Tornos Mas P, Vilacosta I, Zamorano JL; Document Reviewers, Erol Ç, Nihoyannopoulos P, Aboyans V, Agewall S, Athanassopoulos G, Aytekin S, Benzer W, Bueno H, Broekhuizen L, Carerj S, Cosyns B, De Backer J, De Bonis M, Dimopoulos K, Donal E, Drexel H, Flachskampf FA, Hall R, Halvorsen S, Hoen B, Kirchhof P, Lainscak M, Leite-Moreira AF, Lip GY, Mestres CA, Piepoli MF, Punjabi PP, Rapezzi C, Rosenhek R, Siebens K, Tamargo J, Walker DM. Eur Heart J. 2015 Nov 21;36(44):3075-128

3) Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Rodriguez Muñoz D, Rosenhek R, Sjögren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL; ESC Scientific Document Group. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2017 Sep 21;38(36):2739-2791. doi: 10.1093/eurheartj/ehx391

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Pagina 5 - Curriculum vitae di [ DE BONIS, Michele ]

Position papers of the European Society of Cardiology He also promoted and finalized the following important "position paper" on surgical and trans-catheter treatment of mitral regurgitation coordinating the activity of two Working Groups of the European Society of Cardiology (Cardiovascular Surgery and Valvular Heart Disease). This scientific contribution was deemed worthy of publication in the prestigious European Heart Journal:

- Surgical and interventional management of mitral valve regurgitation: a position statement from the European Society of Cardiology Working Groups on Cardiovascular Surgery and Valvular Heart Disease. De Bonis M, Al-Attar N, Antunes M, Borger M, Casselman F, Falk V, Folliguet T, Iung B, Lancellotti P, Lentini S, Maisano F, Messika-Zeitoun D, Muneretto C, Pibarot P, Pierard L, Punjabi P, Rosenhek R, Suwalski P, Vahanian A, Wendler O, Prendergast B. Eur Heart J. 2016 Jan 7;37(2):133-9

• 2017-present

• 2017-present

• 2017-present

• 2016-present

• 2016-present

• 2015-present

• 2015-present

• 2014-present

• 2016-present

Fellowship of the European Society of Cardiology The scientific and organizational activities carried out for the European Society of Cardiology have earned him in 2015 the award of the title of Fellow of the European Society of Cardiology (FESC).

Positions held in International Societies and Scientific Associations:

Chairman of the Task Force on Mitral and Tricuspid Surgery of the European Association for Cardiothoracic Surgery

Ex officio Board Member of the Council on Valvular Heart Disease of the European Society of Cardiology

Member of the SCIENTIFIC & CLINICAL EDUCATION LIFELONG LEARNING (SCILL) COMMITTEE, of the Council on Cardiovascular Surgery & Anesthesia (CVSA) of the American Heart Association for: 1) adult education, 2) program evaluation.

Member of the Oversight Committee of the European Society of Cardiology for the Educational Programme “Awareness in Mitral Regurgitation”

Fellow of the European Society of Cardiology (FESC)

“European Liaison” of the Leadership Committee Commission of Council on Cardiovascular Surgery and Anesthesia of the American Heart Association

Member of the Task Force of the Guidelines on Management of Valvular Heart Disease of the European Society of Cardiology and European Association for Cardiothoracic Surgery (Version 2017)

Member of the Task Force of the 2018 version of the ESC Guidelines on Cardiovascular Diseases during Pregnancy

Past-Chairman of the Working Group for Cardiovascular Surgery of the European Society of Cardiology

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Pagina 6 - Curriculum vitae di [ DE BONIS, Michele ]

• 2016-present

• 2015-2016

• 2012-2016

• 2010- 2014

• 2010-2014

• 2009-2011

• 2009-present

Chairman of the Working Group for Cardiovascular Surgery of the European Society of Cardiology

Coordinator of the “ Committee for Guidelines and Position Papers" and member of the “Committee for the relationships with the European Association for Cardiothoracic Surgery” of the Italian Society of Cardiac Surgery

Member of the “Acquired Cardiac Disease Domain” of the European Association for Cardiothoracic Surgery

Secretary of the Nucleus of the Working Group for Cardiovascular Surgery of the European Society of Cardiology

Member of the Task Force of the Guidelines on Management of Valvular Heart Disease of the European Society of Cardiology and European Association for Cardiothoracic Surgery (Version 2012)

Member of the Nucleus of the Working Group for Cardiovascular Surgery of the European Society of Cardiology

Membership in National and International Societies of Cardiology and Cardiac Surgery:

Member of the “European Association for Cardiothoracic Surgery”

Member of the American Heart Association

Member of the European Society of Cardiology

Member of the Italian Society of Cardiac Surgery

EDUCATION

• 1993

• May 1998

• March 1998

• July 1995 - January 1996

• August 1995-January 1996

MD degree (110/110 cum laude)

Catholic University of the Sacred Heart Medical School, Rome, Italy

United States Medical Licensing Examination (USMLE) Certification (Riconoscimento e parificazione della Laurea in Medicina e Chirurgia negli Stati Uniti).

“Full registration” at the General Medical Council (United Kingdom) under the Medical Act 1983 in the Principal List of the register of medical practitioners (Registration No.: 4486077).

Full time fellowship at the European Homograft Bank International Association, Bruxelles, Belgium (Director Prof. Y.A. Goffin)

Postgraduate Visiting Fellowships - Department of Cardiac Surgery

Onze Lieve Vrouw Clinic, Aalst, Belgium (Director Dr. H. Vanermen).

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• August 1997

• October 1998-1999

• 1994-1999

• April-May 2008

PRIZES AND AWARDS

ACADEMIC QUALIFICATION

- Department of Cardiac Surgery Brugmann University Hospital and Queen Fabiola University Hospital for Children, Bruxelles, Belgium (Director Prof. F.E. Deuvaert).

Postgraduate Visiting Fellowship Department of Cardiothoracic Surgery St. George’s Hospital, University of London, London, United Kingdom (Director Prof. T. Treasure).

Specialist Registrar in Cardiothoracic Surgery Department of Cardiothoracic Surgery St. George’s Hospital, University of London, London, United Kingdom (Consultants: Mr. J.A.R. Gaer, Prof. T. Treasure, Mr. V. Chandrasekaren, Mr. A. Murday, Mr. J. Smith).

Full Training in Cardiac Surgery (50/50 cum laude)

Catholic University of the Sacred Heart Medical School, Rome, Italy

Thesis: “Tacrolimus as a rescue immunosuppressant for refractory rejection after cardiac transplantation”

Visiting Fellowship in mechanical circulatory support (ECMO, VAD, Total Artificial Heart) German Heart Institute, Berlin, Germany (Director: Prof. R. Hetzer)

• Honorable mention during the sixth edition of "Premio Medicine Prof.

P. Petrone" for his MD thesis entitled "Non-pharmacological treatment of atrial fibrillation". Potenza, Italy, December 2, 1995.

• National Award Ciociaria Medicine 2005. Fiuggi, January 22, 2005.

• “Lucani insigni” Prize. Potenza 25th March, 2018

From 2017 he is the Director of the Cardiac Surgery Training School of San Raffaele University Medical School, Milan.

He has been teaching for many years at the Medical School, Nursing School and Training School in Cardiac Surgery of Vita-Salute San Raffaele University in Milan (Italy) in quality of:

Associate Professor of Cardiac Surgery at “Vita e Salute” San Raffaele University Medical School, Milan, Italy (since 2016).

Contract Professor of Cardiac Surgery (SSD MED/23) at “Vita e Salute” San Raffaele University Medical School, Milan, Italy (since 2008). Courses and lectures on: - "Mechanical circulatory support" (Academic years 2008-2009, 2009-2010,

2010-2011, 2012-2013, 2013-2014).

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- "Surgical options for heart failure"(Academic years 2009-2010, 2010-2011, 2011-2012, 2013-2014, 2014-2015, 2015-2016, 2016-present)

Contract Professor of Cardiac Surgery at the Nursing School of “Vita e Salute” San Raffaele University Medical School, Milan, Italy (since 2007)

Contract Professor of Cardiac Surgery at the training School in Cardiac Surgery of “Vita e Salute” San Raffaele University Medical School, Milan, Italy (since 2007). He has been mentoring the trainees of the training school in cardiac surgery and he has been giving lectures and elective courses in order to promote the comprehensive training of the medical students in the field of cardiac surgery. The satisfaction questionnaires filled out by the students systematically confirmed over the years the attitude to teaching with an interactive and engaging approach. He has been coordinating more than 20 thesis in Medicine and Nursing.

Lecturer at the European School for Cardiothoracic Surgery/EACTS Academy Since 2003 he has been having intense lecturing and teaching activities at the European School for Cardiothoracic Surgery of Bergamo (Italy) and at the Academy of the European Association for Cardiothoracic Surgery in Windsor (Great Britain) (fundamental and advanced courses). He has been promoting "wet-labs" on the surgical repair of the mitral and tricuspid valves which have been periodically held at the EACTS Academy. In addition he has been leading similar courses during the 2015, 2016 and editions of the Congress of the European Association for Cardiothoracic Surgery.

Contract Professor at Politecnico of Milano as lecturer and coordinator of the PhD course “3D printing and modeling: towards patient’s tailored treatment and surgical planning”within the Bioengineering PhD Program 2017-2018

SCIENTIFIC QUALIFICATION Extensive scientific experience in the field of adult cardiac surgery with specific reference to surgical and percutaneous techniques for mitral and tricuspid valve repair. The scientific production is relevant (>160 peer reviewed papers, > 200 overall publications) and characterized by continuity over the years. He has been giving more than 180 presentations, mainly at international congresses.

He has been co-editor of the following book on mitral valve repair:

• Edge-to-Edge Mitral Repair: From a Surgical to a Percutaneous Approach.O. Alfieri, M. De Bonis, G. La Canna. (editors). Springer International Publishing Switzerland 2015. ISBN: 978-3-319-19892-7 (Print) 978-3-319-19893-4 (Online) DOI 10.1007/978-3-319-19893-4_7

In addition he has been Author of 14 chapters in Cardiac Surgery textbooks (see references).

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Funded peer-reviewed research projects:

• Progetto CCM (Centro Nazionale per la Prevenzione e il Controllo delle Malattie): Supporto extracorporeo cardiorespiratorio con ECMO (extracorporeal membrane oxygenation) in pazienti con scompenso cardiaco: miglioramento dell'outcome e prevenzione delle complicanze" (2008). Partner: CNR Istituto di Bioimmagini e Fisiologia Molecolare, Milano Funding: euro 500.000 Role: co-operating officer.

• Studio di superfici bioattive per l’ottimizzazione degli LVADs (Left Ventricular Assis Devices): BIOSUOVAD (bioactive surfaces for optimized LVAD). Project funded under the call for proposals for the testing of development initiatives, development of human capital and transfer of research results with direct impact on the Lombard territory issued by the Italian Interuniversity Consortium for Science and Technology of Materials (INSTM) on December 5, 2012 in implementation of the Agreement of cooperation signed between the Region of Lombardy and the INSTM on November 13, 2012. Duration: 15/5/ 2013-15/5/2015 Funding: euro 40.000 Role: Co-Investigator of the INSTM Research Unit San Raffaele Hospital

Member of the Clinical Event Committee (CEC Committee) of the Surtavi Randomized Trial (TAVI versus Surgical aortic valve replacement in intermediate risk patients) (2014-present)

Chairman of the “Adverse Events Safety Board” of the Prevent Study for the percutaneous treatment of tricuspid regurgitation with Tri-cinch (4-Tech) system (2013-present)

Associate Editor/Editorial Board Member of the following International Journals

• Associate Editor ✓ International Journal of Cardiology

• Member of the Editoral Board ✓ Interactive journal of cardiovascular and thoracic surgery ✓ Annals of Cardiology and Cardiovascular Diseases ✓ Heart, Lung and Vessels (previously HSR Proceedings in

Intensive Care and Cardiovascular Medicine).

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Pagina 10 - Curriculum vitae di [ DE BONIS, Michele ]

PATENT AND TECHNOLOGY

TRANSFER

Inventor of an original trans-catheter device for the percutaneous treatment of tricuspid regurgitation (Star-Tric System, European Patent Office number IT201700052909)

Pubblications indexed in PubMed

1. Alessandrini F, De Bonis M, Lapenna E, Morelli M, Possati GF. Posterior-septal pseudo-pseudoaneurysm with limited left-to-right shunt: an unexpected easy repair. J Cardiovasc Surg (Torino). 1999; 40:539-41.

2. De Bonis M, Cavaliere F, Alessandrini F, Lapenna E, Santarelli F, Moscato U, Schiavello R, Possati GF. Topical use of tranexamic acid in coronary artery bypass operations: a double- blind, prospective, randomized, placebo-controlled study. J Thorac Cardiovasc Surg. 2000 Mar;119(3):575-80.

3. De Bonis M, Reynolds L, Barros J, Madden BP. Tacrolimus as a rescue immunosuppressant after heart transplantation. Eur J Cardiothorac Surg. 2001 May;19(5):690-5.

4. Luciani N, Lapenna E, De Bonis M, Possati GF. Mediastinitis following graft replacement of the ascending aorta: conservative approach by omental transposition. Eur J Cardiothorac Surg. 2001 Aug;20(2):418-20.

5. Alfieri O, Maisano F, De Bonis M, Stefano PL, Torracca L, Oppizzi M, La Canna G. The double-orifice technique in mitral valve repair: a simple solution for complex problems. J Thorac Cardiovasc Surg. 2001 Oct;122(4):674-81.

6. Galante A, Pietroiusti A, Vellini M, Piccolo P, Possati G, De Bonis M, Grillo RL, Fontana C, Favalli C. C-reactive protein is increased in patients with degenerative aortic valvular stenosis. J Am Coll Cardiol. 2001 Oct;38(4):1078-82.

7. Alfieri O, De Bonis M. [One or two mammary arteries for surgical revascularization of the myocardium?] Ital Heart J. 2001 Dec;2(12 Suppl):1365-6.

8. Maisano F, Franze V, De Bonis M, Alfieri O. Off-pump coronary artery surgery with the use of anastomotic devices: an additional tool for the challenging patient. Heart Surg Forum. 2002;5(1):25-7.

9. Agricola E, Maisano F, Oppizzi M, De Bonis M, Torracca L, La Canna G, Alfieri O.

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Mitral valve reserve in double-orifice technique: an exercise echocardiographic study. J Heart Valve Dis. 2002 Sep;11(5):637-43.

10. Luciani N, Lapenna E, De Bonis M, Pirronti T, Possati GF. Simultaneous surgical treatment of chronic post-traumatic aneurysm of the thoracic aorta, diaphragmatic hernia and giant emphysema bulla. J Cardiovasc Surg (Torino). 2002 Oct;43(5):747-9.

11. Agricola E, Oppizzi M, De Bonis M, Maisano F, Toracca L, Bove T, Alfieri O. Multiplane transesophageal echocardiography performed according to the guidelines of the American Society of Echocardiography in patients with mitral valve prolapse, flail, and endocarditis: diagnostic accuracy in the identification of mitral regurgitant defects by correlation with surgical findings. J Am Soc Echocardiogr. 2003 Jan;16(1):61-6.

12. Agricola E, Oppizzi M, Maisano F, Bove T, De Bonis M, Toracca L, Alfieri O. Detection of mechanisms of immediate failure by transesophageal echocardiography in quadrangular resection mitral valve repair technique for severe mitral regurgitation. Am J Cardiol. 2003 Jan 15;91(2):175-9.

13. Alessandrini F, Lapenna E, Nasso G, De Bonis M, Possati GF. Successful thrombectomy for thrombosis of aortic composite valve graft in pregnancy. Ann Thorac Surg. 2003 Apr;75(4):1317-8.

14. Alfieri O, Savini C, De Bonis M, Lapenna E. Treatment of patients with concomitant coronary and carotid lesions. Ital Heart J. 2003 Jun;4(6):374-8. Review.

15. Aortic and mitral valve surgery through a superior ministernotomy in pectus excavatum associated with Marfan’s syndrome. M. De Bonis, F. Maisano, E. Lapenna, O. Alfieri. Interactive Cardiovascular and Thoracic Surgery 2003; 2:146-8.

16. Alfieri O, De Bonis M, Lapenna E, Agricola E, Quarti A, Maisano F. The "clover technique" as a novel approach for correction of post-traumatic tricuspid regurgitation. J Thorac Cardiovasc Surg. 2003 Jul;126(1):75-9.

17. Maisano F, Caldarola A, Blasio A, De Bonis M, La Canna G, Alfieri O. Midterm results of edge-to-edge mitral valve repair without annuloplasty. J Thorac Cardiovasc Surg. 2003 Dec;126(6):1987-97.

18. Lapenna E, De Bonis M, Torracca L, La Canna G, Dell'Antonio G, Alfieri O. Cavernous hemangioma of the tricuspid valve: minimally invasive surgical resection. Ann Thorac Surg. 2003 Dec;76(6):2097-9.

19. Agricola E, Galderisi M, Oppizzi M, Schinkel AF, Maisano F, De Bonis M, Margonato A, Maseri A, Alfieri O.

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Pulsed tissue Doppler imaging detects early myocardial dysfunction in asymptomatic patients with severe mitral regurgitation. Heart. 2004 Apr;90(4):406-10.

20. De Bonis M, Lapenna E, La Canna G, Grimaldi A, Maisano F, Torracca L, Caldarola A, Alfieri O. A novel technique for correction of severe tricuspid valve regurgitation due to complex lesions. Eur J Cardiothorac Surg. 2004 May;25(5):760-5.

21. De Bonis M, Lapenna E, Ficarra E, La Canna G, Verzini A, Pagliaro M, Castiglioni A, Maisano F, Torracca L, Benussi S, Alfieri O. Surgical options in ischemic cardiomyopathy. Ital Heart J. 2004 Jun;5 Suppl 6:100S-107S. Review.

22. Alfieri O, De Bonis M, Lapenna E, Regesta T, Maisano F, Torracca L, La Canna G. "Edge-to-edge" repair for anterior mitral leaflet prolapse. Semin Thorac Cardiovasc Surg. 2004;16(2):182-7.

23. Agricola E, Oppizzi M, Maisano F, De Bonis M, Schinkel AF, Torracca L, Margonato A, Melisurgo G, Alfieri O. Echocardiographic classification of chronic ischemic mitral regurgitation caused by restricted motion according to tethering pattern. Eur J Echocardiogr. 2004 Oct;5(5):326-34.

24. Livi U, Alfieri O, Vitali E, Russo C, Frigerio M, Tursi V, Albanese MC, De Bonis M, Fragasso G, Franco-Cereceda A, Forssell G, Rorke R, Kubo SH. One-year clinical experience with the Acorn CorCap cardiac support device: results of a limited market release safety study in Italy and Sweden. Ital Heart J. 2005 Jan;6(1):59-65.

25. Maisano F, Ziskind Z, Grimaldi A, Blasio A, Caldarola A, De Bonis M, La Canna G, Alfieri O. Selective reduction of the septolateral dimensions in functional mitral regurgitation by modified-shape ring annuloplasty. J Thorac Cardiovasc Surg. 2005 Feb;129(2):472-4.

26. Lapenna E, Torracca L, De Bonis M, La Canna G, Crescenzi G, Alfieri O. Minimally invasive mitral valve repair in the context of Barlow's disease. Ann Thorac Surg. 2005 May;79(5):1496-9.

27. M. De Bonis, E. Lapenna, G. La Canna, E. Ficarra, M. Pagliaro, L. Torracca, F. Maisano, O. Alfieri. Mitral valve repair for functional mitral regurgitation in end-stage dilated cardiomyopathy: the role of the “edge-to-edge” technique. Circulation 2005;112[suppl I]:I 402-I408.

28. L. Torracca, E. Lapenna, M. De Bonis, S. Kassem, G. La Canna, G. Crescenzi, A. Castiglioni, A. Grimaldi, O. Alfieri. Minimally invasive mitral valve repair as a routine approach in selected patients.

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Journal of Cardiovascular Medicine 2006;7:57-60.

29. M. De Bonis, R. Lorusso, E. Lapenna, S. Kassem, G. De Cicco, L. Torracca, F. Maisano, G. La Canna, O. Alfieri. Similar long-term results of mitral valve repair for anterior compared with posterior leaflet prolapse. J Thorac Cardiovasc Surg. 2006 Feb;131(2):364-70.

30. M. De Bonis, E Lapenna, G La Canna, A Verzini, A Grimaldi, F Sorrentino, A Castiglioni, L Torracca, F Maisano, S Benussi, O Alfieri. Conventional surgery for congestive heart failure. G Ital Cardiol (Rome) 2006 Apr; 7(4):241-51.Review.

31. M. De Bonis, O. Alfieri Surgery Insight: surgical methods to reverse left ventricular remodeling. Nat Clin Pract Cardiovasc Med. 2006;3(9): 507-13.

32. E. Lapenna, D. Rapati, P. Cardano, M. De Bonis, F. Lullo, A. Zangrillo, O. Alfieri. Spinal cord stimulation for patients with refractory angina and previous coronary surgery. Ann Thorac Surg 2006; 82(5):1704-8

33 R. Lorusso, M. De Bonis, G. De Cicco, F. Maisano, C. Fucci, O. Alfieri. Mitral Insufficiency and Its Different Etiologies. Old and New Insights for Appropriate Surgical Indications and Treatment. J Cardiovasc Med 2007; 8(2):108-13.

34. E. Lapenna, L. Torracca, M. De Bonis, O. Alfieri. A giant right coronary artery-to-superior vena cava fistola. Eur J Cardiothorac Surg 2007; 31(3):546.

35. O. Alfieri, M. De Bonis, F. Maisano, G. La Canna. Future directions in degenerative mitral valve repair. Semin Thorac Cardiovasc Surg 2007;19:127-132.

36. Torracca L, Verzini A, De Bonis M, Alfieri O. Influence of concomitant mitral valve dysfunction on survival after aortic valve replacement. J Cardiovasc Surg (Torino). 2007 Dec;48(6):797-800.

37. M. De Bonis, O. Alfieri. Surgical methods to reverse left ventricular remodeling. Curr Heart Fail Rep. 2007 Dec;4(4):214-20. Review.

38. M. De Bonis, E. Lapenna, A. Verzini, G. La Canna, A. Grimaldi, L. Torracca, F. Maisano, O. Alfieri. Recurrence of mitral regurgitation parallels the absence of left ventricular reverse remodeling after mitral repair in advanced dilated cardiomyopathy. Ann Thorac Surg. 2008 Mar;85(3):932-9.

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39. M. De Bonis, E. Lapenna, F. Sorrentino, G. La Canna, A. Grimaldi, F. Maisano, L. Torracca, O. Alfieri. Evolution of tricuspid regurgitation after mitral valve repair for functional mitral regurgitation in dilated cardiomyopathy Eur J Cardiothorac Surg. 2008 Apr;33(4):600-6.

40. Lorusso R, Gelsomino S, De Cicco G, Beghi C, Russo C, De Bonis M, Colli A, Sala A. Mitral valve surgery in emergency for severe acute regurgitation: analysis of postoperative results from a multicentre study. Eur J Cardiothorac Surg. 2008; 33(4):573-82.

41. Lapenna E, De Bonis M, Sorrentino F, La Canna G, Grimaldi A, Torracca L, Maisano F, Alfieri O.Commissural closure for the treatment of commissural mitral valve prolapse or flail. The Journal of heart valve disease 2008;17:261-6.

42. M. De Bonis, Ottavio Alfieri Mitral regurgitation should be corrected in patients with dilated cardiomyopathy Nat Clin Pract Cardiovasc Med. 2008 Aug;5(8):452-3.

43. Lapenna E, De Bonis M, Maisano F, Crescenzi G, La Canna G, Torracca L, Grimaldi A, Alfieri O. 'Four-leaflet clover repair' of severe tricuspid valve regurgitation due to complex lesions. J Cardiovasc Med (Hagerstown). 2008 Aug;9(8):847-9.

44. La Canna G, Maisano F, De Michele L, Grimaldi A, Grassi F, Capritti E, De Bonis M, Alfieri O. Determinants of the Degree of Functional Aortic Regurgitation in Patients With Anatomically Normal Aortic Valve and Ascending Thoracic Aorta Aneurysm Transesophageal Doppler Echocardiography Study. Heart. 2009 Feb;95(2):130-6.

45. Taramasso M, De Bonis M, Lapenna E, Verzini A, La Canna G, Grimaldi A, Alfieri O. Reverse remodeling effect of the CorCap despite the presence of severe mitral regurgitation. Ann Thorac Surg. 2009 Mar;87(3):e23-4.

46. Grimaldi A, Collu E, Castiglioni A, La Canna G, De Bonis M, Bignami E, Melisurgo G, Alfieri O. A “four-leaflet clover” aortic valve. HSR proceedings in Intensive Care and Cardiovascular Anestesia 2010; 2:137- 138.

47. E. Collu, A. Grimaldi, S. Benussi, A. Castiglioni, E. Bignami, N. Rizzo, M. De Bonis, G. Melisurgo, G. La Canna, O. Alfieri A rare case of unexpected cardiac incidentaloma causing syncope HSR Proceedings in Intensive Care and Cardiovascular Anesthesia 2010; 2: 225- 227

48. Alfieri O, De Bonis M. Mitral valve repair for functional mitral regurgitation: is annuloplasty alone enough?

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Curr Opin Cardiol. 2010 Mar;25(2):114-8.

49. E. Lapenna, M. De Bonis, A. Verzini, G. La Canna, D. Ferrara, M.C. Calabrese, M. Taramasso, O. Alfieri. The clover technique for the treatment of complex tricuspid valve insufficiency: midterm clinical and echocardiographic results in 66 patients. Eur J Cardiothorac Surg 2010;37(6):1297-303

50. Alfieri O, De Bonis M. The role of the edge-to-edge repair in the surgical treatment of mitral regurgitation. J Cardiac Surgery 2010;25(5):536-541

51. De Bonis M, Alfieri O. The Edge-to-Edge Technique for mitral valve repair. HSR proceedings in Intensive Care and Cardiovascular Medicine 2010;2:7-17.

52. Barosi A, Lunati M, Speca G, Mazzola A, Paglino G, De Bonis M, Iacopino S, Cassese M, Dicandia CD, Esposito G, Vimercati M, Della Scala A, Vitali E. Cardiac resynchronization therapy in patients undergoing open-chest cardiac surgery. J Interv Card Electrophysiol. 2011;30(3):251-259.

53. La Canna G, Arendar I, Maisano F, Monaco F, Collu E, Benussi S, De Bonis M, Castiglioni A, Alfieri O. Real-time three-dimensional transesophageal echocardiography for assessment of mitral valve functional anatomy in patients with prolapse-related regurgitation. Am J Cardiol 2011;107(9):1365-74.

54. Alfieri O, De Bonis M. Re: Spratt J. Non-resectional repair of myxomatous mitral valve disease: the 'American Correction'. J Heart Valve Dis 2011;20:407-414. J Heart Valve Dis. 2011 Jul;20(4):415-6.

55. De Bonis M, Taramasso M, Grimaldi A, Maisano F, Calabrese MC, Verzini A, Ferrara D, Alfieri O. The GeoForm annuloplasty ring for the surgical treatment of functional mitral regurgitation in advanced dilated cardiomyopathy. Eur J Cardiothorac Surg. 2011; 40 (2):488-95.

56. Grimaldi A, Castiglioni A, De Bonis M, Alfieri O. Large left ventricular aneurysm. J Thorac Cardiovasc Surg. 2011 Oct;142(4):940-1.

57. De Bonis M, Maisano F, Canna GL, Alfieri O. Treatment and management of mitral regurgitation. Nat Rev Cardiol. 2011 Nov 22;9(3):133-46.

58. Grimaldi A, Capritti E, Pappalardo F, Radinovic A, Ferrarello S, Cammalleri V, Collu E, Ammirati E, Fumero A, Benussi S, De Bonis M, Zangrillo A, Alfieri O.

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Blood cyst of the mitral valve. J Cardiovasc Med (Hagerstown). 2012 Jan;13(1):46.

59. Grimaldi A, Ammirati E, La Canna G, Sora N, Faletra F, De Bonis M, Maisano F, Castiglioni A, Colombo A, Alfieri O. Echocardiographic “brainstorm” to detect anomalous origin of the left coronary artery from the pulmonary artery. J Cardiovasc Med (Hagerstown). 2012 Feb;13(2):152-5.

60. De Bonis M, Taramasso M, Verzini A, Ferrara D, Lapenna E, Calabrese MC, Grimaldi A, Alfieri O. Long-term results of mitral repair for functional mitral regurgitation in idiopathic dilated cardiomyopathy. Eur J Cardiothorac Surg. 2012;42(4):640-6.

61. Grimaldi A, Ajello S, Scandroglio M, Melisurgo G, Gardini C, De Bonis M, Bove T, Calabrò MG, Maj G, Zangrillo A, Pappalardo F. Intracardiac Clots Masked by Extracorporeal Membrane Oxygenation Venous Cannula. J Cardiothorac Vasc Anesth. 2012 Apr;26(2):e13-4.

62. De Bonis M, Lapenna E, Taramasso M, Manca M, Calabrese MC, Buzzatti N, Rossodivita A, Pappalardo F, Dorigo E, Alfieri O. Mid-term results of tricuspid annuloplasty with a three-dimensional remodelling ring. J Card Surg. 2012 May;27(3):288-94.

63. Gelsomino S, Maessen JG, van der Veen F, Livi U, Renzulli A, Lucà F, Carella R, Crudeli E, Rubino A, Rostagno C, Russo C, Borghetti V, Beghi C, De Bonis M, Gensini GF, Lorusso R. Emergency surgery for native mitral valve endocarditis: the impact of septic and cardiogenic shock. Ann Thorac Surg. 2012 May;93(5):1469-76.

64. Pieri M, Greco T, De Bonis M, Mai G, Fumagalli L, ZangrilloA and Pappalardo F. Diagnosis of infection in patients undergoing extracorporeal membrane oxygenation: a case control study. J Thorac Cardiovasc Surg. 2012 Jun;143(6):1411-1416.

65. Grimaldi A, Olivotto I, Figini F, Pappalardo F, Capritti E, Ammirati E, Maisano F, Benussi S, Fumero A, Castiglioni A, De Bonis M, Vermi AC, Colombo A, Zangrillo A, Alfieri O. Dynamic assessment of 'valvular reserve capacity' in patients with rheumatic mitral stenosis. Eur Heart J Cardiovasc Imaging. 2012 Jun;13(6):476-82.

66. Grimaldi A, De Bonis M, Pappalardo F, Taramasso M, Verzini A, Calabrese MC, Malsano F, Alfieri O. Undersized annuloplasty for functional mitral regurgitation: is it responsible for clinically relevant mitral stenosis during exercise? J Heart Valve Dis 2012;21(4):446-53.

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67. De Bonis M, Ferrara D, Taramasso M, Calabrese MC, Verzini A, Buzzatti N, Alfieri O. Mitral Replacement or Repair for Functional Mitral Regurgitation in Dilated and Ischemic Cardiomyopathy: Is it Really the Same? Ann Thorac Surg. 2012 Jul;94(1):44-51

68. Maj G, De Bonis M, Pieri M, Melisurgo G, Pappalardo F. Extracorporeal life support for refractory cardiac arrest: what is a good outcome? Intensive Care Med. 2012 Aug 15.

69. Authors/Task Force Members, Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Barón-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Iung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M; ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S; Document Reviewers:, Popescu BA, Von Segesser L, Badano LP, Bunc M, Claeys MJ, Drinkovic N, Filippatos G, Habib G, Kappetein AP, Kassab R, Lip GY, Moat N, Nickenig G, Otto CM, Pepper J, Piazza N, Pieper PG, Rosenhek R, Shuka N, Schwammenthal E, Schwitter J, Mas PT, Trindade PT, Walther T. Guidelines on the management of valvular heart disease (version 2012): The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2012 Oct;33(19):2451-96.

70. Taramasso M, Denti P, Buzzati N, De Bonis M, La Canna G, Colombo A, Alfieri O, Maisano F. Mitraclip therapy and surgical mitral repair in patients with moderate to severe left ventricular failure causing functional mitral regurgitation: a single-center experience. Eur J Cardiothorac Surg. 2012 Dec;42(6):920-6.

71. Authors/Task Force Members, Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Barón-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Iung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M; ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S; Document Reviewers, Popescu BA, Von Segesser L, Badano LP, Bunc M, Claeys MJ, Drinkovic N, Filippatos G, Habib G, Kappetein AP, Kassab R, Lip GY, Moat N, Nickenig G, Otto CM, Pepper J, Piazza N, Pieper PG, Rosenhek R, Shuka N, Schwammenthal E, Schwitter J, Mas PT, Trindade PT, Walther T. Guidelines on the management of valvular heart disease (version 2012): The Joint Task Force on the Management of Valvular Heart Disease of the

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European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg. 2012 Oct;42(4):S1-44.

72. Infections occurring in adult patients receiving mechanical circulatory support: The two-year experience of an Italian National Referral Tertiary Care Center. Pieri M, Agracheva N, Fumagalli L, Greco T, De Bonis M, Calabrese MC, Rossodivita A, Zangrillo A, Pappalardo F. Med Intensiva. 2013 Oct;37(7):468-75.

73. [Evolution in surgical repair of heart valves: implications for follow-up]. De Bonis M, Taramasso M, Lapenna E, Pozzoli A, Calabrese MC, Nisi T, Alfieri O. G Ital Cardiol (Rome). 2012 Nov;13(11):714-22.

74. Emergent repair of a complex dissecting aneurysm in the thoracic aorta. Civilini E, Bertoglio L, Mascia D, De Bonis M, Chiesa R. Tex Heart Inst J. 2012;39(5):687-91.

75. Is flow really continuous in last generation continuous flow Ventricular Assist Devices? A comparison between HeartMate II and HeartWare HVAD. Melisurgo G, De Bonis M, Pieri M, Nisi T, Silvetti S, Zangrillo A, Pappalardo F. HSR Proc Intensive Care Cardiovasc Anesth. 2012;4(4):268-9.

76. De Bonis M, Lapenna E, Lorusso R, Buzzati N, Gelsomino S, Taramasso M, Vizzardi E, Alfieri O. Very long-term results (up to 17 years) with the double-orifice mitral valve repair combined with ring annuloplasty for degenerative mitral regurgitation. J Thorac Cardiovasc Surg. 2012; 144(5):1019-24.

77. De Bonis M, Bolling SF. Mitral valve surgery: wait and see vs early operation. Eur Heart J. 2013 Jan;34(1):13-19.

78. Bivalirudin versus heparin as an anticoagulant during extracorporeal membrane oxygenation: a case-control study. Pieri M, Agracheva N, Bonaveglio E, Greco T, De Bonis M, Covello RD, Zangrillo A, Pappalardo F. J Cardiothorac Vasc Anesth. 2013 Feb;27(1):30-4.

79. Edge-to-edge Alfieri technique for mitral valve repair: which indications? De Bonis M, Lapenna E, Alfieri O. Curr Opin Cardiol. 2013 Jan;28(2):152-7.

80. Pappalardo F, Pieri M, Greco T, Patroniti N, Pesenti A, Arcadipane A, Ranieri VM, Gattinoni L, Landoni G, Holzgraefe B, Beutel G, Zangrillo A; Italian ECMOnet (Scandroglio AM, Calabrò MG, Bove T, De Bonis M, Foti G, Bombino M, Peris A, Cianchi G, Pasquini A, Braschi A, Mojoli F, Zanierato M, Iotti GA, Belliato M, Carnevale L, Terragni P, Urbino R, Del Sorbo L, Fanelli V, Panarello G, Antonelli M, Bello G, Maviglia R, Lissoni A, Crotti S, Pietropaoli P,

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Rocco M, Morelli A, Frascaroli G, Caramelli F, Tufano R, Iannuzzi M, Bruno F, Grasso S, Lorini L, Ori C, Rossi S, Persona P). Predicting mortality risk in patients undergoing venovenous ECMO for ARDS due to influenza A (H1N1) pneumonia: the ECMOnet score. Intensive Care Med. 2013 Feb;39(2):275-81.

81. Tricuspid valve surgery for severe tricuspid regurgitation. Alfieri O, De Bonis M. Heart. 2013 Feb;99(3):149-50.

82. Reply to the editor. De Bonis M, Lapenna E, Alfieri O. J Thorac Cardiovasc Surg. 2013 Jan;145(1):316.

83. Gastrointestinal bleeding and coagulation disorders in a patient with left- ventricular assist device. Correale M, Ieva R, Pappalardo F, Santoro F, De Bonis M, Di Biase M. J Cardiovasc Med (Hagerstown). 2013 Feb;14(2):173-4.

84. Secondary mitral regurgitation in patients undergoing aortic valve replacement. De Bonis M, Lapenna E, Giacomini A, Alfieri O. Eur J Cardiothorac Surg. 2013;44(1):40-1.

85. Can the edge-to-edge technique provide durable results when used to rescue patients with suboptimal conventional mitral repair? De Bonis M, Lapenna E, Buzzatti N, Taramasso M, Calabrese MC, Nisi T, Pappalardo F, Alfieri O. Eur J Cardiothorac Surg. 2013;43(6):e173-9.

86.[Guidelines on the management of valvular heart disease (version 2012). The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)]. Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Baron-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Iung B, Lancellotti P, Pierard L, Price S, Schafers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M. G Ital Cardiol (Rome). 2013 Mar;14(3):167-214

87. Cardiac support with IABP during venovenous ECMO for ARDS. Pappalardo F, Pieri M, De Bonis M, Maj G, Calabrò MG, Ajello S, Melisurgo G, Zangrillo A. Intensive Care Med. 2013 Jun;39(6):1152-3.

88. Aortic Cannula Disruption Following Long-Term LVAD Support. Pappalardo F, Nisi T, Melisurgo G, Calabrese M, De Bonis M. J Card Surg. 2013 Jul;28(4):472-4.

89. Primary Anticoagulation With Bivalirudin for Patients With Implantable Ventricular Assist Devices.

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Pieri M, Agracheva N, Di Prima AL, Nisi T, De Bonis M, Isella F, Zangrillo A, Pappalardo F. Artif Organs. 2014 Apr;38(4):342-6

90. Is commissural closure associated with mitral annuloplasty a durable technique for the treatment of mitral regurgitation? A long-term (≤15 years) clinical and echocardiographic study. De Bonis M, Lapenna E, Taramasso M, Pozzoli A, La Canna G, Calabrese MC, Alfieri O. J Thorac Cardiovasc Surg. 2014;147(6):1900-6.

91. MitraClip and right ventricular function: hopes and doubts. De Bonis M, Alfieri O. Eur Heart J Cardiovasc Imaging. 2014 Jan;15(1):104-5.

92. Anticoagulation for Critically Ill Cardiac Surgery Patients: Is Primary Bivalirudin the Next Step? Pappalardo F, Agracheva N, Covello RD, Pieri M, De Bonis M, Calabrò MG, Koster A, Zangrillo A. J Cardiothorac Vasc Anesth. 2014 Aug;28(4):1025-9.

93. Long-term outcomes of tricuspid valve replacement after previous left-side heart surgery. Buzzatti N, Iaci G, Taramasso M, Nisi T, Lapenna E, De Bonis M, Maisano F, Alfieri O. Eur J Cardiothorac Surg. 2014 Oct;46(4):713-9.

94. Conventional surgery and transcatheter closure via surgical transapical approach for paravalvular leak repair in high-risk patients: results from a single- centre experience. Taramasso M, Maisano F, Latib A, Denti P, Guidotti A, Sticchi A, Panoulas V, Giustino G, Pozzoli A, Buzzatti N, Cota L, De Bonis M, Montorfano M, Castiglioni A, Blasio A, La Canna G, Colombo A, Alfieri O. Eur Heart J Cardiovasc Imaging. 2014 Oct;15(10):1161-7.

95. Very long-term durability of the edge-to-edge repair for isolated anterior mitral leaflet prolapse: Up to 21 years of clinical and echocardiographic results. De Bonis M, Lapenna E, Taramasso M, La Canna G, Buzzatti N, Pappalardo F, Alfieri O. J Thorac Cardiovasc Surg. 2014 Nov;148(5):2027-32.

96. ECLS management in pulmonary embolism with cardiac arrest: Which strategy is better? Maj G, Melisurgo G, De Bonis M, Pappalardo F. Resuscitation. 2014 Oct;85(10):e175-6.

97. Management of tricuspid regurgitation. De Bonis M, Taramasso M, Lapenna E, Alfieri O. F1000 Med Rep 2014, 6:58 (doi:10.12703/P6-58).

98. Long-Term Results (≤18 Years) of the Edge-to-Edge Mitral Valve Repair Without Annuloplasty in Degenerative Mitral Regurgitation: Implications for the Percutaneous Approach.

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De Bonis M, Lapenna E, Maisano F, Barili F, La Canna G, Buzzatti N, Pappalardo F, Calabrese M, Nisi T, Alfieri O. Circulation. 2014 Sep 9;130(11 Suppl 1):S19-24.

99. TAVR-Associated Prosthetic Valve Infective Endocarditis : Results of a Large, Multicenter Registry. Latib A, Naim C, De Bonis M, Sinning JM, Maisano F, Barbanti M, Parolari A, Lorusso R, Testa L, Actis Dato GM, Miceli A, Sponga S, Rosato F, De Vincentiis C, Werner N, Fiorina C, Bartorelli A, Di Gregorio O, Casilli F, Muratori M, Alamanni F, Glauber M, Livi U, Nickenig G, Tamburino C. Journal of the American College of Cardiology 2014; 64: 2176-2178.

100. Spectroscopic and Morphological Characterization of Inflow Cannulas of Left Ventricular Assist Devices. Pappalardo F, Cristaldi DA, Fragalà IL, Millesi S, De Bonis M, Gulino A. ASAIO J. 2015 Mar-Apr;61(2):150-5.

101. Edge-to-edge surgical mitral valve repair in the era of MitraClip: what if the annuloplasty ring is missed? De Bonis M, Lapenna E, Pozzoli A, Giacomini A, Alfieri O. Curr Opin Cardiol. 2015;30:155-160.

102. Surgical treatment of paravalvular leak: Long-term results in a single- center experience (up to 14 years). Taramasso M, Maisano F, Denti P, Guidotti A, Sticchi A, Pozzoli A, Buzzatti N, De Bonis M, La Canna G, Alfieri O. J Thorac Cardiovasc Surg. 2015 May;149(5):1270-5

103. Dual lumen catheter cannulation for venovenous ECMO. Pappalardo F, Ruggeri L, Pieri M, Maj G, De Bonis M, Zangrillo A. Intensive Care Med. 2015 May;41(5):941-2.

104. MitraClip therapy and surgical edge-to-edge repair in patients with severe left ventricular dysfunction and secondary mitral regurgitation: mid-term results of a single-centre experience† De Bonis M, Taramasso M, Lapenna E, Denti P, La Canna G, Buzzatti N, Pappalardo F, Di Giannuario G, Cioni M, Giacomini A, Alfieri O. Eur J Cardiothorac Surg. 2016 Jan;49(1):255-62

105. Timing and Strategy for Weaning From Venoarterial ECMO are Complex Issues. Pappalardo F, Pieri M, Arnaez Corada B, Ajello S, Melisurgo G, De Bonis M, Zangrillo A. J Cardiothorac Vasc Anesth. 2015 Aug;29(4):906-11.

106. Surgical and interventional management of mitral valve regurgitation: a position statement from the European Society of Cardiology Working Groups on Cardiovascular Surgery and Valvular Heart Disease. De Bonis M, Al-Attar N, Antunes M, Borger M, Casselman F, Falk V, Folliguet T, Iung B, Lancellotti P, Lentini S, Maisano F, Messika-Zeitoun D, Muneretto C, Pibarot P, Pierard L, Punjabi P, Rosenhek R, Suwalski P, Vahanian A, Wendler O, Prendergast B. Eur Heart J 2016 Jan 7;37(2):133-9.

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107. Contemporary application of the edge-to-edge repair. Pozzoli A, Vicentini L, De Bonis M, Di Giannuario G, La Canna G, Alfieri O. Ann Cardiothorac Surg 2015;4(4):376-379.

108. 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC)Endorsed by: European Association for Cardio- Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Authors/Task Force Members, Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos-Hesselink J, Snygg-Martin U, Thuny F, Tornos Mas P, Vilacosta I, Zamorano JL. Collaborators: Erol Ç, Nihoyannopoulos P, Aboyans V, Agewall S, Athanassopoulos G, Aytekin S, Benzer W, Bueno H, Broekhuizen L, Carerj S, Cosyns B, De Backer J, De Bonis M, Dimopoulos K, Donal E, Drexel H, Flachskampf FA, Hall R, Halvorsen S, Hoen B, Kirchhof P, Lainscak M, Leite- Moreira AF, Lip GY, Mestres CA, Piepoli MF, Punjabi PP, Rapezzi C, Rosenhek R, Siebens K, Tamargo J, Walker DM. Eur Heart J. 2015 Nov 21;36(44):3075-128.

109. Mitral Valve Repair Without Repair of Moderate Tricuspid Regurgitation. De Bonis M, Lapenna E, Pozzoli A, Nisi T, Giacomini A, Calabrese M, La Canna G, Pappalardo F, Miceli A, Glauber M, Barili F, Alfieri O. Ann Thorac Surg. 2015 Dec;100(6):2206-12.

110. Veno-arterial Extracorporeal Membrane oxygenation for acute fulminant myocarditis in adult patients: a 5-year multi institutional experience. Lorusso R, Centofanti P, Gelsomino S, Barili F, Di Mauro M, Parise O, Botta L, Actis Dato G, Casabona Riccardo, Casali G, Musumeci F, De Bonis M, Zangrillo A, Alfieri O, Pellegrini C, Mazzola S, Coletti G,Vizzardi E, Bianco R, Gerosa G, Massetti M, Caldaroni F, Pilato E, Di Bartolomeo R, Marinelli G, Sponga S, Livi U, Rinaldi M, Mariscalco G, Beghi C, Miceli A, Glauber M, Pappalardo F, Russo CF on behalf of the GIROC Investigators. Ann Thorac Surg. 2016 Mar;101(3):919-26.

111. What is a "good" result after transcatheter mitral repair? Impact of 2+ residual mitral regurgitation. Buzzatti N, De Bonis M, Denti P, Barili F, Schiavi D, Di Giannuario G, La Canna G, Alfieri O. J Thorac Cardiovasc Surg. 2016 Jan;151(1):88-96.

112. Hemodynamic and echocardiographic effects of aortic regurgitation on femoro-femoral veno-arterial ECMO. Pappalardo F, Regazzoli D, Mangieri A, Ajello S, Melisurgo G, Agricola E, Baratto F, Ruparelia N, Oppizzi M, De Bonis M, Colombo A, Zangrillo A, Della Bella P. Int J Cardiol. 2015 Oct 9;202:760-762.

113. The contemporary role of Impella in a comprehensive mechanical circulatory support program: a single institutional experience.

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Pieri M, Contri R, Winterton D, Montorfano M, Colombo A, Zangrillo A, De Bonis M, Pappalardo F. BMC Cardiovasc Disord. 2015 Oct 14;15(1):126.

114. A comparison of conventional surgery, transcatheter aortic valve replacement, and sutureless valves in "real-world" patients with aortic stenosis and intermediate- to high-risk profile. Muneretto C, Alfieri O, Cesana BM, Bisleri G, De Bonis M, Di Bartolomeo R, Savini C, Folesani G, Di Bacco L, Rambaldini M, Maureira JP, Laborde F, Tespili M, Repossini A, Folliguet T. J Thorac Cardiovasc Surg. 2015 Dec;150(6):1570-9.

115. Prognostic Impact and Late Evolution of Untreated Moderate (2/4+) Functional Tricuspid Regurgitation in Patients Undergoing Aortic Valve Replacement. Taramasso M, Maisano F, De Bonis M, Pozzoli A, Schiavi D, Benussi S, Grimaldi A, La Canna G, Alfieri O. J Card Surg. 2016;31(1);9-14.

116. Percutaneous Transcatheter Treatment for Tricuspid Bioprosthesis Failure. Ruparelia N, Mangieri A, Ancona M, Giannini F, Agricola E, Montorfano M, De Bonis M, Alfieri O, Colombo A, Latib A. Catheter Cardiovasc Interv. 2016 May 17. doi: 10.1002/ccd.26584

117. Long-term results of mitral repair in patients with severe left ventricular dysfunction and secondary mitral regurgitation: does the technique matter? De Bonis M, Lapenna E, Barili F, Nisi T, Calabrese M, Pappalardo F, La Canna G, Pozzoli A, Buzzatti N, Giacomini A, Alati E, Alfieri O. Eur J Cardiothorac Surg. 2016 Nov;50(5):882-889 . 118. Optimal results immediately after MitraClip therapy or surgical edge-to- edge repair for functional mitral regurgitation: are they really stable at 4 years? De Bonis M, Lapenna E, Buzzatti N, La Canna G, Denti P, Pappalardo F, Schiavi D, Pozzoli A, Cioni M, Di Giannuario G, Alfieri O. Eur J Cardiothorac Surg. 2016 Sep;50(3):488-94

119. Antiplatelet versus oral anticoagulant therapy as antithrombotic prophylaxis after mitral valve repair. Paparella D, Di Mauro M, Bitton Worms K, Bolotin G, Russo C, Trunfio S, Scrofani R, Antona C, Actis Dato G, Casabona R, Colli A, Gerosa G, Renzulli A, Serraino F, Scrascia G, Zaccaria S, De Bonis M, Taramasso M, Delgado L, Tritto F, Marmo J, Parolari A, Myaseodova V, Villa E, Troise G, Nicolini F, Gherli T, Whitlock R, Conte M, Barili F, Gelsomino S, Lorusso R, Sciatti E, Marinelli D, Di Giammarco G, Calafiore AM, Sheikh A, Alfonso JJ, Glauber M, Miceli A; GIROC Investigators. J Thorac Cardiovasc Surg. 2016 May;151(5):1302-1308.

120. Mitral valve repair. Pozzoli A, De Bonis M, Alfieri O. F1000Res. 2016 Jun 10;5. pii: F1000 Faculty Rev-1326. doi: 10.12688/f1000research.7521.1. eCollection 2016. Review.

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121. Surgical indication for functional tricuspid regurgitation at initial operation: judging from long term outcomes. Pozzoli A, Elisabetta L, Vicentini L, Alfieri O, De Bonis M. Gen Thorac Cardiovasc Surg. 2016 Sep;64(9):509-16. doi: 10.1007/s11748- 016-0677-5. Epub 2016 Jun 21. Review.

122. Tricuspid Annular Size and Regurgitation Progression After Surgical Repair for Degenerative Mitral Regurgitation. Sordelli C, Lancellotti P, Carlomagno G, Di Giannuario G, Alati E, De Bonis M, Alfieri O, La Canna G. Am J Cardiol. 2016 Aug 1;118(3):424-31.

123. Concomitant implantation of Impella® on top of veno-arterial extracorporeal membrane oxygenation may improve survival of patients with cardiogenic shock. Pappalardo F, Schulte C, Pieri M, Schrage B, Contri R, Soeffker G, Greco T, Lembo R, Müllerleile K, Colombo A, Sydow K, De Bonis M, Wagner F, Reichenspurner H, Blankenberg S, Zangrillo A, Westermann D. Eur J Heart Fail. 2016 Oct 6. doi: 10.1002/ejhf.668. [Epub ahead of print]

124. Post-infarct ventricular septal rupture: early Impella implantation to delay surgery and reduce surgical risk. Ancona MB, Regazzoli D, Mangieri A, Monaco F, De Bonis M, Latib A. Cardiovasc Interv Ther. 2016 Sep 7.

125. Pozzoli A, Buzzatti N, Vicentini L, De Bonis M, Alfieri O. Results of tricuspid valve surgery for functional tricuspid regurgitation: acute and long-term outcomes and predictors of failure. Minerva Cardioangiol. 2017 Oct;65(5):491-499. doi: 10.23736/S0026-4725.17.04350-X. Caricato ma pdf Full text non disponibile

126. Valve Repair: A Durable Surgical Option in Degenerative Mitral Regurgitation. Prendergast BD, De Bonis M. Circulation. 2017 Jan 31;135(5):423-425. doi: 10.1161/CIRCULATIONAHA.116.026280.

127. Reverse Left Ventricular Remodeling Causing Severe Mitral Regurgitation After Bentall Procedure. Trumello C, Denti P, Calabrese MC, Di Giannuario G, La Canna G, Bignami E, Alfieri O, De Bonis M. Ann Thorac Surg. 2017 Jan;103(1):e85-e86. doi: 10.1016/j.athoracsur.2016.05.021

128. A predictive model for early mortality after surgical treatment of heart valve or prosthesis infective endocarditis. The EndoSCORE. Di Mauro M, Dato GMA, Barili F, Gelsomino S, Santè P, Corte AD, Carrozza A, Ratta ED, Cugola D, Galletti L, Devotini R, Casabona R, Santini F, Salsano A, Scrofani R, Antona C, Botta L, Russo C, Mancuso S, Rinaldi M, De Vincentiis C, Biondi A, Beghi C, Cappabianca G, Tarzia V, Gerosa G, De Bonis M, Pozzoli A, Nicolini F, Benassi F, Rosato F, Grasso E, Livi U, Sandro S, Pacini

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D, Di Bartolomeo R, De Martino A, Bortolotti U, Onorati F, Faggian G, Lorusso R, Vizzardi E, Di Giammarco G, Marinelli D, Villa E, Troise G, Picichè M, Musumeci F, Paparella D, Margari V, Tritto F, Damiani G, Scrascia G, Zaccaria S, Renzulli A, Serraino G, Mariscalco G, Maselli D, Foschi M, Parolari A, Nappi G; Italian Group of Research for Outcome in Cardiac Surgery (GIROC). Int J Cardiol. 2017 Aug 15;241:97-102. doi: 10.1016/j.ijcard.2017.03.148.

129. First in man prolonged pressure-controlled intermittent coronary sinus occlusion to treat refractory left ventricular dysfunction and ischemia with patent epicardial coronary arteries. Pappalardo F, Ancona MB, Giannini F, Regazzoli D, Mangieri A, Montorfano M, De Bonis M, Alfieri O, Zangrillo A, Scandroglio AM, Colombo A, Latib A. Int J Cardiol. 2017 Aug 15;241:138-141. doi: 10.1016/j.ijcard.2017.05.030.

130. Tricuspid annuloplasty versus a conservative approach in patients with functional tricuspid regurgitation undergoing left-sided heart valve surgery: A study-level meta-analysis. Pagnesi M, Montalto C, Mangieri A, Agricola E, Puri R, Chiarito M, Ancona MB, Regazzoli D, Testa L, De Bonis M, Moat NE, Rodés-Cabau J, Colombo A, Latib A. Int J Cardiol. 2017 Aug 1;240:138-144. doi: 10.1016/j.ijcard.2017.05.014.

131. Mid-term outcomes of concomitant surgical ablation of atrial fibrillation in patients undergoing cardiac surgery for hypertrophic cardiomyopathy. Lapenna E, Pozzoli A, De Bonis M, La Canna G, Nisi T, Nascimbene S, Vicentini L, Di Sanzo S, Del Forno B, Schiavi D, Alfieri O. Eur J Cardiothorac Surg. 2017 Jun 1;51(6):1112-1118. doi: 10.1093/ejcts/ezx017.

132. The flaws in the detail of an observational study on transcatheter aortic valve implantation versus surgical aortic valve replacement in intermediate- risks patients. Barili F, Freemantle N, Folliguet T, Muneretto C, De Bonis M, Czerny M, Obadia JF, Al-Attar N, Bonaros N, Kluin J, Lorusso R, Punjabi P, Sadaba R, Suwalski P, Benedetto U, Böning A, Falk V, Sousa-Uva M, Kappetein PA, Menicanti L. Eur J Cardiothorac Surg. 2017 Jun 1;51(6):1031-1035. doi: 10.1093/ejcts/ezx058.

133. Luciani N, Mossuto E, Ricci D, Luciani M, Russo M, Salsano A, Pozzoli A, Pierri MD, D'Onofrio A, Chiariello GA, Glieca F, Canziani A, Rinaldi M, Nardi P, Milazzo V, Trecarichi EM, Santini F, De Bonis M, Torracca L, Bizzotto E, Tumbarello M. Prosthetic valve endocarditis: predictors of early outcome of surgical therapy. A multicentric study. Eur J Cardiothorac Surg. 2017 Oct 1;52(4):768-774. doi: 10.1093/ejcts/ezx169.

134. De Bonis M, Lapenna E, Del Forno B, Di Sanzo S, Giacomini A, Schiavi D, Vicentini L, Latib A, Pozzoli A, Pappalardo F, La Canna G, Alfieri O. Minimally invasive or conventional edge-to-edge repair for severe mitral regurgitation due to bileaflet prolapse in Barlow's disease: does the surgical approach have an impact on the long-term results? Eur J Cardiothorac Surg. 2017 Jul 1;52(1):131-136. doi: 10.1093/ejcts/ezx032.

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135. . Stepwise use of circulatory support devices in a patient refractory to cardiopulmonary resuscitation. Spartera M, Jabbour RJ, Chiarito M, De Bonis M, Pappalardo F. Cardiovasc Revasc Med. 2017 Sep;18(6):447-449. doi:10.1016/j.carrev.2017.04.001. Epub 2017 Apr 8.

136. Use of a parallel stiff wire to facilitate percutaneous Impella RP ventricular assist device positioning. Giannini F, Montorfano M, Jabbour RJ, Latib A, Ruparelia N, Azzalini L, Magni V, Romano V, De Bonis M, Pappalardo F, Colombo A. Cardiovasc Revasc Med. 2017 Mar 15. pii: S1553-8389(17)30071-4. doi: 10.1016/j.carrev.2017.03.012.

137. Surgery for prosthetic valve endocarditis: a retrospective study of a national registry. Della Corte A, Di Mauro M, Actis Dato G, Barili F, Cugola D, Gelsomino S, Santè P, Carozza A, Della Ratta E, Galletti L, Devotini R, Casabona R, Santini F, Salsano A, Scrofani R, Antona C, De Vincentiis C, Biondi A, Beghi C, Cappabianca G, De Bonis M, Pozzoli A, Nicolini F, Benassi F, Pacini D, Di Bartolomeo R, De Martino A, Bortolotti U, Lorusso R, Vizzardi E, Di Giammarco G, Marinelli D, Villa E, Troise G, Paparella D, Margari V, Tritto F, Damiani G, Scrascia G, Zaccaria S, Renzulli A, Serraino G, Mariscalco G, Maselli D, Parolari A, Nappi G. Eur J Cardiothorac Surg. 2017 Mar 13. doi: 10.1093/ejcts/ezx045.

138. Does implantation of a single clip provide reliable durability after transcatheter mitral repair?. Buzzatti N, Denti P, La Canna G, Schiavi D, Vicentini L, Scarfò IS, Caso I, De Bonis M, Alfieri O. Eur J Cardiothorac Surg. 2017 Jul 1;52(1):137-142. doi: 10.1093/ejcts/ezx044.

139. De Bonis M, Lapenna E, Di Sanzo S, Del Forno B, Pappalardo F, Castiglioni A, Vicentini L, Pozzoli A, Giambuzzi I, Latib A, Schiavi D, La Canna G, Alfieri O. Long-term results (up to 14 years) of the clover technique for the treatment of complex tricuspid valve regurgitation. Eur J Cardiothorac Surg. 2017 Jul 1;52(1):125-130. doi: 10.1093/ejcts/ezx027.

140. Del Forno B, Castiglioni A, Sala A, Geretto A, Giacomini A, Denti P, De Bonis M, Alfieri O. Mitral valve annuloplasty. Multimed Man Cardiothorac Surg. 2017 Oct 6;2017. doi: 10.1510/mmcts.2017.016.

141. Consolo F, Sferrazza G, Motolone G, Contri R, Valerio L, Lembo R, Pozzi L, Della Valle P, De Bonis M, Zangrillo A, Fiore GB, Redaelli A, Slepian MJ, Pappalardo F. Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device. Eur J Heart Fail. 2017 Dec 28. doi: 10.1002/ejhf.1113.

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142. Falk V, Baumgartner H, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Muñoz DR, Rosenhek R, Sjögren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL, Roffi M, Alfieri O, Agewall S, Ahlsson A, Barbato E, Bueno H, Collet JP, Coman IM, Czerny M, Delgado V, Fitzsimons D, Folliguet T, Gaemperli O, Habib G, Harringer W, Haude M, Hindricks G, Katus HA, Knuuti J, Kolh P, Leclercq C, McDonagh TA, Piepoli MF, Pierard LA, Ponikowski P, Rosano GMC, Ruschitzka F, Shlyakhto E, Simpson IA, Sousa-Uva M, Stepinska J, Tarantini G, Tchétché D, Aboyans V. Corrigendum to '2017 ESC/EACTS Guidelines for the management of valvular heart disease' [Eur J Cardiothorac Surg 2017;52:616-664]. Eur J Cardiothorac Surg. 2017 Oct 1;52(4):832. doi: 10.1093/ejcts/ezx363.

143. Falk V, Baumgartner H, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Muñoz DR, Rosenhek R, Sjögren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL; ESC Scientific Document Group. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur J Cardiothorac Surg. 2017 Oct 1;52(4):616-664. doi: 10.1093/ejcts/ezx324.

144. De Bonis M, Alfieri O, Dalrymple-Hay M, Del Forno B, Dulguerov F, Dreyfus G. Mitral Valve Repair in Degenerative Mitral Regurgitation: State of the Art. Prog Cardiovasc Dis. 2017 Nov - Dec;60(3):386-393. doi:10.1016/j.pcad.2017.10.006. Epub 2017 Nov 5.

145. Denti P, Pozzoli A, Geretto A, Vicentini L, Di Sanzo S, Monaco F, Crivellari M, Buzzatti N, De Bonis M, La Canna G, Redaelli A, Alfieri O. Systolic anterior motion after mitral valve repair: a predictive computational model. Interact Cardiovasc Thorac Surg. 2017 Oct 1;25(4):513-519. doi: 10.1093/icvts/ivx186.

146. Antunes MJ, Rodríguez-Palomares J, Prendergast B, De Bonis M, Rosenhek R, Al-Attar N, Barili F, Casselman F, Folliguet T, Iung B, Lancellotti P, Muneretto C, Obadia JF, Pierard L, Suwalski P, Zamorano P; ESC Working Groups of Cardiovascular Surgery and Valvular Heart Disease. Management of tricuspid valve regurgitation: Position statement of the European Society of Cardiology Working Groups of Cardiovascular Surgery and Valvular Heart Disease. Eur J Cardiothorac Surg. 2017 Dec 1;52(6):1022-1030. doi: 10.1093/ejcts/ezx279.

147. Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Rodriguez Muñoz D, Rosenhek R, Sjögren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL; ESC Scientific Document Group. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2017 Sep 21;38(36):2739-2791. doi: 10.1093/eurheartj/ehx391.

148. Valgimigli M, Bueno H, Byrne RA, Collet JP, Costa F, Jeppsson A, Jüni P, Kastrati A, Kolh P, Mauri L, Montalescot G, Neumann FJ, Petricevic M, Roffi M,

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Steg PG, Windecker S, Zamorano JL, Levine GN; Collaborators: Badimon L, Vranckx P, Agewall S, Andreotti F, Antman E, Barbato E, Bassand JP, Bugiardini R, Cikirikcioglu M, Cuisset T, De Bonis M, Delgado V, Fitzsimons D, Gaemperli O, Galiè N, Gilard M, Hamm CW, Ibanez B, Iung B, James S, Knuuti J, Landmesser U, Leclercq C, Lettino M, Lip G, Piepoli MF, Pierard L, Schwerzmann M, Sechtem U, Simpson IA, Uva MS, Stabile E, Storey RF, Tendera M, Van de Werf F, Verheugt F, Aboyans V. ESC Scientific Document Group. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS. Eur J Cardiothorac Surg. 2018 Jan 1;53(1):34-78. doi: 10.1093/ejcts/ezx334.

149. Gammie JS, Bartus K, Gackowski A, D'Ambra MN, Szymanski P, Bilewska A, Kusmierczyk M, Kapelak B, Rzucidlo-Resil J, Moat N, Duncan A, Yadev R, Livesey S, Diprose P, Gerosa G, D'Onofrio A, Pitterello D, Denti P, La Canna G, De Bonis M, Alfieri O, Hung J, Kolsut P. Beating-Heart Mitral Valve Repair Using a Novel ePTFE Cordal Implantation Device: A Prospective Trial. J Am Coll Cardiol. 2018 Jan 2;71(1):25-36. doi: 10.1016/j.jacc.2017.10.062.

150. Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Muñoz DR, Rosenhek R, Sjögren J, Mas PT, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL. 2017 ESC/EACTS Guidelines for the Management of Valvular Heart Disease. Rev Esp Cardiol (Engl Ed). 2018 Feb;71(2):110. doi: 10.1016/j.rec.2017.12.013.

151. De Bonis M, Lapenna E, Giambuzzi I, Meneghin R, Affronti G, Pappalardo F, Castiglioni A, Trumello C, Buzzatti N, Giacomini A, Raimondi Lucchetti M, Alfieri O. Second cross-clamping after mitral valve repair for degenerative disease in contemporary practice. Eur J Cardiothorac Surg. 2018 Jan 22. doi: 10.1093/ejcts/ezx507.

152. Iung B, Delgado V, Lazure P, Murray S, Sirnes PA, Rosenhek R, Price S, Metra M, Carrera C, De Bonis M, Haude M, Hindricks G, Bax J, Vahanian A. Educational needs and application of guidelines in the management of patients with mitral regurgitation. A European mixed-methods study. Eur Heart J. 2018 Jan 2. doi: 10.1093/eurheartj/ehx763.

153. Buzzatti N, De Bonis M, Moat N. Anatomy of the Tricuspid Valve, Pathophysiology of Functional Tricuspid Regurgitation, and Implications for Percutaneous Therapies. Interv Cardiol Clin. 2018 Jan;7(1):1-11. doi: 10.1016/j.iccl.2017.08.005.

154. Valgimigli M, Bueno H, Byrne RA, Collet JP, Costa F, Jeppsson A, Jüni P, Kastrati A, Kolh P, Mauri L, Montalescot G, Neumann FJ, Petricevic M, Roffi M, Steg PG, Windecker S, Zamorano JL, Levine GN; Collaborators: Badimon L, Vranckx P, Agewall S, Andreotti F, Antman E, Barbato E, Bassand JP, Bugiardini R, Cikirikcioglu M, Cuisset T, De Bonis M, Delgado V, Fitzsimons D, Gaemperli O, Galiè N, Gilard M, Hamm CW, Ibanez B, Iung B, James S, Knuuti J, Landmesser U, Leclercq C, Lettino M, Lip G, Piepoli MF, Pierard L, Schwerzmann M, Sechtem U, Simpson IA, Uva MS, Stabile E, Storey RF, Tendera M, Van de Werf F, Verheugt F, Aboyans V, Windecker S, Aboyans V, Agewall S, Barbato E, Bueno H, Coca A, Collet JP,

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Coman IM, Dean V, Delgado V, Fitzsimons D, Gaemperli O, Hindricks G, Iung B, Jüni P, Katus HA, Knuuti J, Lancellotti P, Leclercq C, McDonagh T, Piepoli MF, Ponikowski P, Richter DJ, Roffi M, Shlyakhto E, Simpson IA, Zamorano JL, Windecker S, Aboyans V, Agewall S, Barbato E, Bueno H, Coca A, Collet JP, Coman IM, Dean V, Delgado V, Fitzsimons D, Gaemperli O, Hindricks G, Iung B, Jüni P, Katus HA, Knuuti J, Lancellotti P, Leclercq C, McDonagh T, Piepoli MF, Ponikowski P, Richter DJ, Roffi M, Shlyakhto E, Simpson IA, Zamorano JL, Roithinger FX, Aliyev F, Stelmashok V, Desmet W, Postadzhiyan A, Georghiou GP, Motovska Z, Grove EL, Marandi T, Kiviniemi T, Kedev S, Gilard M, Massberg S, Alexopoulos D, Kiss RG, Gudmundsdottir IJ, McFadden EP, Lev E, De Luca L, Sugraliyev A, Haliti E, Mirrakhimov E, Latkovskis G, Petrauskiene B, Huijnen S, Magri CJ, Cherradi R, Ten Berg JM, Eritsland J, Budaj A, Aguiar CT, Duplyakov D, Zavatta M, Antonijevic NM, Motovska Z, Fras Z, Montoliu AT, Varenhorst C, Tsakiris D, Addad F, Aydogdu S, Parkhomenko A, Kinnaird T. ESC Scientific Document Group ; ESC Committee for Practice Guidelines (CPG) ; ESC National Cardiac Societies . 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: The Task Force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2018 Jan 14;39(3):213-260. doi: 10.1093/eurheartj/ehx419.

Other pubblications

1. F. Alessandrini, P. Santarelli, F. Bellocci, F. Pennestrì, A. Lombardo, G.A. Lanza, R. Zamparelli, R. Schiavello, M. De Bonis, C. Marchetti, S. Bartoccioni, F. Glieca, N. Luciani, A.M. Calafiore, G.F. Possati. Trattamento chirurgico della fibrillazione atriale associata a valvulopatia mitralica. “Maze Procedure” e chirurgia della mitrale. Arch. Chir. Torac. Cardiovasc. 1994; 16: 1-12.

2. F. Glieca, F. Alessandrini, C. Marchetti, C. Canosa, C. De Filippo, M. De Bonis, G.F. Possati. Il chilotorace dopo intervento di rivascolarizzazione miocardica con arteria mammaria interna. Ann. Med. e Chir. VII: 1993; 27-30

3. N. Luciani, M. Morelli, C. Canosa, C. Marchetti, C. De Filippo, M. De Bonis. Trattamento chirurgico delle infezioni da elettrocatetere di pace-maker. Il Cuore vol XI, 1994; 231-36.

4. F. Glieca, N. Luciani, F. Alessandrini, M. Morelli, C. Cellini, M. De Bonis, C. Marchetti, A. Buffon, G.F. Possati. Trattamento chirurgico dell’origine anomala dell’arteria coronaria sinistra dall’arteria polmonare. La Chirurgia Toracica 1994; 47: 73-79.

5. F. Glieca, G. Santarelli, G. Colombo, M. De Bonis, C. Marchetti, C. Canosa, C. De Filippo.

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Valutazione clinica di un ossigenatore a fibre cave di ultima generazione: Capiox SX. By Pass vol. VII, 1994; 2: 540-44.

6. N. Luciani, F. Glieca, C. De Filippo, M. De Bonis, C. Canosa, C. Marchetti, C. Dominici. Granulomatosi di Wegener ed insufficienza valvolare aortica. Il Cuore vol VII, 1995; 6: 437-42.

7. M. De Bonis, T. Treasure. Benefits of endoscopic saphenous vein harvesting. World J Surg 2000; 24:1104-8

8. M. De Bonis, E. Lapenna, O. Alfieri. The “Edge-to-edge” technique in mitral valve repair.

Heart views 2002;3:164-9.

9. O. Alfieri, M. De Bonis, E. Lapenna. Nuove acquisizioni in tema di chirurgia valvolare. Medici Oggi 2002; vol. Giugno-Luglio, pages 278-80.

10. Lapenna E, De Bonis M, La Canna G, Alfieri O. Ruolo e timing della cardiochirurgia nel prolasso mitralico. Indicazioni, tecniche operatorie, risultati. Cardiology Science 2006; 4: 113-117.

11. E. Lapenna, M. De Bonis, O. Alfieri. Indicazioni e timing chirurgico nella patologia valvolare aortica. Cardiology Science 2008;6:76-82.

12. M. De Bonis, O Alfieri. Future directions in degenerative mitral valve repair. European Cardiology 2008;4:88-91.

13. Alfieri O., De Bonis M. Repair options for mitral regurgitation. European Cardiology 2011;5:2-6.

14. De Bonis M, Taramasso M, Lapenna E, Alfieri O. Degenerative mitral valve repair. European Journal of Cardiovascular Medicine 2011;1(3):42-44.

15.. The “edge-to-edge” repair. O. Alfieri, F. Maisano, M. De Bonis. Multimedia Manual of Cardiothoracic Surgery (on-line in Internet).

16. Traumatic tricuspid regurgitation. Invited commentary. M. De Bonis, O. Alfieri Multimedia Manual of Cardiothoracic Surgery (on-line in Internet, www.mmcts.org).

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Chapters of books in cardiac surgery

1. Diagnostica strumentale dei mixomi cardiaci: fonocardiografia, elettrocardiografia, radiologia, tomografia assiale computerizzata. M. De Bonis and C. Fedeli. In “ I mixomi cardiaci “. Acta Medica Romana 1995; 33 (2): 187-240. Chapter 4: pages 202-209.

2. Trattamento chirugico dei mixomi cardiaci: via di accesso, resezione dei mixomi atriali, resezione dei mixomi ventricolari. C. De Filippo and M. De Bonis. In “ I mixomi cardiaci “. Acta Medica Romana 1995; 33 (2): 187-240. Chapter 8: 224-231.

3. How I Assess and Repair the Barlow Mitral Valve: The Edge-to-Edge Technique. M. De Bonis, O.Alfieri. Mitral valve surgery. Monographs in cardiac surgery, pages 77-84. Bonser RS, Pagano D and Haverich A. Editors Springer, 2011 ISBN: 9781849964258

4. Type A acute aortic dissection M. De Bonis, A. Galanti, M. Nuzzi, A. Zangrillo, O. Alfieri. Endovascular Therapy International (ETI) Book 2009, pages 141-154.

5. Ischemic mitral regurgitation: the role of the edge-to-edge repair. M. De Bonis, O. Alfieri Mitral valve repair. The biological solution by R. Hetzer, J.S. Rankin and C.A. Yankah pag. 167-174. Springer-Verlag Berlin Heidelberg 2011

6. Edge-to-edge technique (role in mitral valve repair) M. De Bonis, O. Alfieri Cardiothoracic Surgery Review by Kenneth L. Franco and Vinod H. Thourani Wolters Kluver Health/Lippincott Williams & Wilkins 2011

7. Principles of mitral repair surgery. Taramasso M, De Bonis M, Alfieri O. In: Tamburino C and Ussia GP. Percutaneous Treatment of Left Side Cardiac Valves: A Practical Guide for interventional cardiologists. (2010) p. 278-287, DORDRECHT:springer, ISBN: 978-88-470-1423-7

8. Mitral valve repair (edge-to-edge). M. De Bonis, O. Alfieri. In: Cardiac Surgery: Technique and practice. Editors K. Franco, E. Roselli, M. Slaughter, V. Thourani 2013.

9. Genesis of the surgical edge-to-edge repair. O. Alfieri, M. De Bonis. In: Percutaneous mitral leaflet repair.

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Edited by Ted Feldman and Frederick St. Goar. Informa healthcare 2012

10. The role of the edge-to-edge in mitral valve repair. O. Alfieri, M. De Bonis. In: K. Fattouch et al. (eds.), Secondary Mitral Valve Regurgitation, © Springer-Verlag London 2015, DOI 10.1007/978-1-4471-6488-3_13,

11. Technical aspects: sternotomy and minimally invasive Fumero A, De Bonis M In: Edge-to-Edge Mitral Repair: From a Surgical to a Percutaneous Approach. O. Alfieri, M. De Bonis, G. La Canna. (editors). Springer International Publishing Switzerland 2015. DOI 10.1007/978-3-319- 19893-4_7

12. Results of the EE repair De Bonis M., Lapenna E., Del Castillo G., Alfieri O. In: Edge-to-Edge Mitral Repair: From a Surgical to a Percutaneous Approach. O. Alfieri, M. De Bonis, G. La Canna. (editors). Springer International Publishing Switzerland 2015. DOI 10.1007/978-3-319- 19893-4_7

13. The case of surgical EE repair without annuloplasty: now we know. Lapenna E, Schiavi D, Del Castillo G, De Bonis M. In: Edge-to-Edge Mitral Repair: From a Surgical to a Percutaneous Approach. O. Alfieri, M. De Bonis, G. La Canna. (editors).

Springer International Publishing Switzerland 2015. DOI 10.1007/978-3-319- 19893-4_7

14. Percutaneous approaches to functional mitral regurgitation M. De Bonis, E. Lapenna. In: Functional Mitral and Tricuspid Regurgitation. John Chan Kok Meng (Editor) Springer International Publishing Switzerland 2015

15. La valvulopatia mitralica Elisabetta Lapenna, Michele De Bonis, Giovanna Di Giannuario, Andrea Giacomini, Teodora Nisi, Denti Paolo, Fumero Andrea, Giovanni La Canna, Ottavio Alfieri. In:Trattato di chirurgia cardiaca by Luigi Chiariello Società Editrice Universo ISBN 9788865151297 / 8865151293 Publisher:Seu, 2016

Publications from national and international workshop proceedings

1. F. Alessandrini, P. Santarelli, S. Bartoccioni, R. Schiavello, M. De Bonis, F. Glieca, C. Marchetti, A.M. Calafiore, G.F. Possati. “Maze Procedure” associata a trattamento chirurgico delle valvulopatie

mitraliche fibrillanti.

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Proceedings from the International Workshop “20 Anni di attività Cardiochirurgica al nuovo Policlinico di Napoli”, Amalfi, Italy, 24-25 September 1993, page 319-337.

2. Il rimodellamento chirurgico: nuove conoscenze, nuove tecniche F. Maisano, M. De Bonis, V. Franzè, J. Schreuder, O. Alfieri. Congresso “Venti anni di terapia intensiva coronarica a Nuoro – VII Corso di Ecocardiografia Clinica”. Orosei 5-6 Ottobre 2001 Atti del Congresso pages 217-28.

3. La tecnica “edge-to-edge” in chirurgia ricostruttiva mitralica: indicazioni e controversie. F. Maisano, M. De Bonis, P. Greco, G. La Canna, A. Redaelli, O. Alfieri. Atti del XX Congresso Nazionale della Società Italiana di Chirurgia Cardiaca, Verona 26-29 Novembre 2000, pages 241-47.

4. Effetti acuti della riduzione del preload sulla insufficienza mitralica: implicazioni sulla chirurgia ricostruttiva della mitrale. F. Maisano, J. Schreuder, E. Agricola, M. Oppizzi, G. La Canna, M. De Bonis, O. Alfieri. Atti del XX Congresso Nazionale della Società Italiana di Chirurgia Cardiaca, Verona 26-29 Novembre 2000, pages 217-20.

5. Chirurgia dell’insufficienza mitralica, ovvero quando la funzione ventricolare sinistra è l’effettiva arbitra della prognosi? M. De Bonis, O Alfieri Cardiologia per immagini 2001, Roma 23-26 Ottore 2001 Atti del Congresso pages 309-14

6. Valvuloplastica mitralica nel 2002 O. Alfieri, M. De Bonis, E. La penna. Cardiologia per immagini 2002, Roma, 2002 Atti del Congresso pages 483-90.

7. La chirurgia riparativa della valvola mitrale in soggetti con bassa frazione d’eiezione. O. Alfieri , M. De Bonis.

Congresso “Conoscere e curare il cuore 2002”, Firenze 8-10 Marzo 2002 Atti XIX simposio del centro per la lotta contro l’infarto pages 253-62.

8. La possibile terapia chirurgica del cuore scompensato M. De Bonis, M. Oppizzi, E. Lapenna, F. Maisano, C. Savini, . Agricola, O. Alfieri. III Congresso Biennale Aterosclerosi, Roma 9-10 Maggio 2002 Atti del Congresso

9. La dilatazione dell’aorta ascendente: il processo decisionale e le tecniche chirurgiche. C. Savini, C. Borsetti, A Quarti, M. De Bonis , O Alfieri International Workshop “Selected topics in aortic surgery II”, Rome 16-18 January 2003 Atti del Congresso pages 11-16.

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10. La chirurgia della valvola aortica: quando e perché. M. De Bonis, E. Lapenna, G. Marino, O. Alfieri. Filosofia, etica e pratica e controversie in Cardiologia e Cardiochirurgia Alessandria, 18-20 Settembre 2003 International Journal of Cardiovascular Diseases 2003;XX;I; 49-52.

11. Chirurgia valvolare: riparazione o sostituzione. O. Alfieri, M. De Bonis, E. Lapenna. Convegno Riabilitazione Cardiologia, Castello di Pandino, 3-4 Ottobre 2003 Atti del Congresso

12. La rivascolarizzazione miocardica nel paziente diabetico. E. La penna , M. De Bonis, O. Alfieri . Cardiologia per immagini 2003, Roma 20-23 Ottobre 2003 Atti del Congresso pages 179-86.

13. Evolving surgical options for ischemic heart failure. O. Alfieri, M. De Bonis. GISE, Genova Ottobre 2003 Atti del Congresso

14. Prolasso della mitrale: l’entità della mixomatosi incide su timing e tecnica della riparazione chirurgica? E. Lapenna, M. De Bonis, Ottavio Alfieri. Atti del Congresso “Conoscere e curare il cuore 2004” Firenze 26-28 Marzo 2004

15. Le nuove tecniche mini-invasive per la chirurgia valvolare cardiaca. E. Lapenna, M. De Bonis, F. Maisano, L. Torracca, O. Alfieri. Atti del XXIII Congresso “Conoscere e curare il cuore 2006” Firenze 24-26 Marzo 2006

16. L’insufficienza mitralica ischemica, emodinamicamente significativa, peggiora tanto la prognosi della cardiopatia ischemica da suggerire l’anuloplastica anche in assenza di scompenso cadiaco? G. La Canna, M. De Bonis, F. Malsano, O. Alfieri. Atti del XXIII Congresso “Conoscere e curare il cuore 2006” Firenze 24-26 Marzo 2006

17. La terapia di resincronizzazione cardiaca in cardiochirurgia: ruolo nel recupero postoperatorio e nel trattamento cronico del paziente affetto da scompenso cardiaco. A. Barosi, E. Catena, P. Cardano, A. Della Scala, A. Sestito, N. Lucani, M. De Bonis, O. Alfieri, E. Vitali. Atti di “Cardiologia 2006 – 40° Convegno Internazionale del Dipartimento Cardiologico A. De Gasperis” pag 254-263. Azienda Ospedaliera Ca Granda Milano-Niguarda, 18-22 Settembre 2006.

18. Il recupero del miocardio leso O. Alfieri, M. De Bonis. Atti del Congresso Corso Fondazione Tonolli, Verbania 2008

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19. Surgery for tricuspid regurgitation late after mitral valve replacement or repair M. De Bonis Postgraduate Course of the 23rd European Association for Cardiothoracic Surgery Meeting, Vienna, Austria, 17-21 October 2009. Postgraduate Course Book

20. Supporti meccanici al circolo: campo di applicazione dei diversi tipi di device. M. De Bonis VAD-EMECUM: conoscere e gestire i VAD. 47° Convegno Cardiologia 2013. Milan 23-27 September 2013. Cardiologia 2013, pag.227-231.

21. Anatomical pitfalls in heart valve surgery M. De Bonis, A. Pozzoli. Postgraduate Course keynote lecture Postgraduate course book 68th Japanese Association for Thoracic Surgery, October 16-20, 2015, Kobe, Japan.

Presentations at national and international meetings with published abstracts

1. Results of the “Maze Procedure” in patients undergoing mitral valve surgery. F. Alessandrini, P. Santarelli, A. Lombardo, F. Pennestrì, F. Glieca, N. Luciani, M. De Bonis, F. Bellocci, C. Marchetti, R. Schiavello, S. Bartoccioni , A.M. Calafiore, G.F. Possati. International Society of Cardiothoracic Surgeons. The seventh annual meeting. Kanazawa, Japan, July 20-22, 1994 (Abstract n. 32, page 79).

2. Il ruolo dell’arteria radiale nella rivascolarizzazione miocardica. E. Manasse, F. Alessandrini, C. Cellini, C. Canosa, C. De Filippo, M. De Bonis, L. Martinelli, R. Schiavello, G.F. Possati. XVII Congresso della Società Italiana di Chirurgia Cardiaca e Vascolare. Archivio di Chirurgia Toracica e Cardiovascolare vol. VII, 1995; 1: 23 (abstract).

3. In vivo vasoreactivity of the radial artery. E. Manasse, G. Sperti, F. Crea, R. Flore, C. Pragliola, M. De Bonis, H. Suma,

A. Maseri, G.F. Possati. 22nd Worl Congress of the International Society for Cardiovascular Surgery. Cardiovascular Surgery, September 1995; volume 3 (suppl. 1), page 146. (Abstract).

4. Emergency coronary bypass grafting for failed percutaneous transluminal coronary angioplasty. A. Scapigliati, M. De Bonis, L. Martinelli, E. Lapenna, F. Alessandrini, R. Zamparelli, G.F. Possati, R. Schiavello. First European Congress on Emergency Medicine. San Marino, April 22-25, 1998.

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5. Correlazione tra attività leucocitaria ed infezione da chlamydia pneumoniae o helicobacter pylori in un gruppo omogeneo di pazienti con cardiopatia ischemica. A. Galante, A. Bergamaschi, G. Possati, M. De Bonis, E. Lapenna, A. Pietroiusti, S. Carta, A. Magrini, G. Comerci, S. Aquilani, C. Razzini, C. Favalli, A. Mastino.

59th Congresso Nazionale della Società Italiana di Cardiologia. Roma, 12-16 Dicembre 1998 Cardiologia vol. 43 (suppl. 3), 1998 : page 53 (Abstract n. 185).

6. Valutazione dell’attività leucocitaria in un gruppo omogeneo di pazienti con angina stabile ed instabile. A.Galante, A. Bergamaschi, G. Possati, M. De Bonis, E. Lapenna, A. Pietroiusti, S. Carta, A. Magrini, G. Comerci, M.C. Fontana, C. Favalli, A. Mastino. 59th Congresso Nazionale della Società Italiana di Cardiologia. Roma, 12-16 Dicembre 1998 Cardiologia vol. 43 (suppl. 3), 1998 : page 109 (Abstract n. 42).

7. Effetti della circolazione extracorporea sul controllo baroriflesso del nodo del seno in pazienti affetti da cardiopatia ischemica. F. Iellamo, J.M. Legramante, M. De Bonis, E. Lapenna, M. Massaro, Raimondi, G Peruzzi, G.F. Possati, A. Galante. 59th Congresso Nazionale della Società Italiana di Cardiologia. Roma, 12-16 Dicembre 1998 Cardiologia vol. 43 (suppl. 3), 1998 : page 113 (Abstract n.60).

8. Correlazione tra infiammazione cronica ed infezione da helicobacter pylori o chlamydia pneumoniae nella cardiopatia ischemica. A.Galante, A. Bergamaschi, G. Possati, M. De Bonis, E. Lapenna, R.L. Grillo,

A. Pietroiusti, S. Carta, A. Magrini, P. Piccolo, L. Franceschelli, M. C. Fontana. 59th Congresso Nazionale della Società Italiana di Cardiologia. Roma, 12-16 Dicembre 1998 Cardiologia vol. 43 (suppl. 3), 1998 : page 52 (Abstract n. 183).

9. Valutazione dei parametri bioumorali di infiammazione cronica in un gruppo omogeneo di pazienti con angina stabile ed instabile. A.Galante, A. Bergamaschi, G. Possati, M. De Bonis, E. Lapenna, R.L. Grillo, A. Pietroiusti, S. Carta, A. Magrini, P. Piccolo, L. Franceschelli, G. Konstantinou. 59th Congresso Nazionale della Società Italiana di Cardiologia.Roma, 12-16 Dicembre 1998 Cardiologia vol. 43 (suppl. 3), 1998 : page 44 (Abstract n. 149).

10. La tecnica “edge-to-edge” nella chirurgia ricostruttiva della valvola mitrale: una soluzione semplice per problemi complessi. M. De Bonis, F. Maisano, PL Stefano, L. Torracca, P. Greco, M. Oppizzi, G. La Canna, O. Alfieri. Atti del XX Congresso Nazionale della Società Italiana di Chirurgia Cardiaca, Verona 26-29 Novembre 2000: page 263 (Abstract n. 150).

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11. La rivascolarizzazione miocardica completa a cuore battente nei pazienti con severa disfunzione ventricolare sinistra. F. Maisano, M. De Bonis, P. Greco, A. Castiglioni, O. Alfieri. XXII Congresso dell’Associazione Nazionale Medici Cardiologi Ospedalieri, Firenze 20-23 Maggio 2001. Italian Heart Journal 2001; 2(Suppl.2), page 12 (Abstract C38).

12. La componente mitralica nella cardiomiopatia ipertrofica ostruttiva: trattamento chirurgico. M. De Bonis , F. Maisano, A. Blasio, PL. Stefano, E. Agricola, M. Oppizzi, G. La Canna, O. Alfieri. XXII Congresso dell’Associazione Nazionale Medici Cardiologi Ospedalieri, Firenze 20-23 Maggio 2001. Italian Heart Journal 2001; 2(Suppl.2), page 14 (Abstract C45).

13. Esperienza clinica preliminare con dispositivi per anastomosi automatiche nel bypass aorto-coronarico a cuore battente. F. Maisano, M. De Bonis, P. Greco, E. Agricola, M. Oppizzi, A. Castiglioni, B. Fiorani, O. Alfieri. XXII Congresso dell’Associazione Nazionale Medici Cardiologi Ospedalieri, Firenze 20-23 Maggio 2001. Italian Heart Journal 2001; 2(Suppl.2), page 72 (Abstract C270).

14. I risultati operatori nel trattamento chirurgico degli aneurismi dell’aorta ascendente ed arco aortico: nostra esperienza in 186 pazienti. B. Fiorani, PL. Stefano, A. Blasio, F. Maisano, M. De Bonis, A. Castiglioni, A. Caldarola, O. Alfieri. XXII Congresso dell’Associazione Nazionale Medici Cardiologi Ospedalieri, Firenze 20-23 Maggio 2001. Italian Heart Journal 2001; 2(Suppl.2), page 99 (Abstract P71).

15. Valve reconstruction in ischemic mitral regurgitation: a surgical strategy based on mechanism classification. F. Maisano, G. La Canna, E. Agricola, M. Oppizzi, M. De Bonis, P. Greco, O. Alfieri. The European Society of Cardiology – XXIII Congress Stockholm 1-5 September 2001. Poster presentation session 301.

16. Presence of mitral valve reserve in double orifice technique: an exercise echocardiographic study. E. Agricola, M. Oppizzi, F. Maisano, M. De Bonis, L. Torracca, O. Alfieri. American Heart Association, Anaheim (California) November 11-14, 2001 Supplement to Circulation 2001;104(17): II-551 (Abstract n. 2606).

17. Acute effects of intra-aortic balloon counterpulsation timing on cardiac performance in patients with low ejection fraction. J. Schreuder, A. Castiglioni, F. Maisano, A. Donelli, M. De Bonis, O. Alfieri. American Heart Association, Anaheim (California) November 11-14, 2001 Supplement to Circulation 2001;104(17): II-419 (Abstract n. 1996).

18. Evolving concepts in mitral valve repair. O. Alfieri, M. De Bonis

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Satellite Symposium Book of the 16th Annual Meeting of the European Association for Cardiothoracic Surgery. Monaco- Montecarlo 23 September 2002.

19. Mid-term results of mitral valve repair in presence of severe ischemic mitral regurgitation and poor left ventricular function. M. De Bonis, E. Lapenna, V. Franzè, C. Savini, M. Oppizzi, F. Maisano, L. Torracca, O. Alfieri. XXI Congresso Nazionale della Società Italiana di Chirurgia Cardiaca, Roma 23-27 Novembre 2002. Book of Abstract page 137 (Abstract n. 92).

20. “Clover technique” for correction of post-traumatic tricuspid regurgitation. M. De Bonis, E. Lapenna, A. Quarti, E. Agricola, O. Alfieri. XXI Congresso Nazionale della Società Italiana di Chirurgia Cardiaca, Roma 23-27 Novembre 2002. Book of Abstract page 212 (Abstract n. 166).

21. Detection of mechanisms of immediate failure in mitral valve repair technique by transesophageal echocardiography: a guide to further repair. E. Agricola, M. Oppizzi, F. Maisano, T. Bove, M. De Bonis, L. Torracca, O. Alfieri. EUROECHO, The Sixth Annual Meeting of the ESC Working Group on Echocardiography, Munich, Germany 4-7 December 2002 European Journal of Echocardiography Abstracts Supplement, December 2002; vol. 3 (Suppl. I), s122 (Abstract 211).

22. Echocardiographic classification of ischemic mitral regurgitation based on mitral leaflet motion, left ventricular remodeling and characteristics of the regurgitant jet. E. Agricola, M. Oppizzi, F. Maisano, M. De Bonis, L. Torracca, G. La Canna, O. Alfieri. American College of Cardiology, 52nd Annual Scientific Session, Chicago, Illinois, March 30-April 2, 2003 American College of Cardiology, 2003;41(6), Suppl. A, page 500 A (Abstract 1084).

23. Chirurgia riparativa della valvola mitrale: risultati. E. Lapenna, M. De Bonis, A. Quarti, L. Torracca, O. Alfieri. XVI Congresso Nazionale Società Polispecialistica Italiana dei Giovani Chirurghi (SPIGC), Milano 1-3 Maggio 2003. Tumori – a journal of experimental and clinical oncology 2003; (Suppl. to volume 89, n.3), page 12.

24. Chirurgia riparativa della valvola mitrale: tecniche chirurgiche. M. De Bonis, E. Lapenna , L. Torracca , A. Quarti, F. Maisano, O. Alfieri. XVI Congresso Nazionale Società Polispecialistica Italiana dei Giovani Chirurghi (SPIGC), Milano 1-3 Maggio 2003. Tumori – a journal of experimental and clinical oncology 2003; (Suppl. to volume 89, n.3), page 12.

25. Maisano F, Caldarola A, Blasio A, De Bonis M, La Canna G, Alfieri O.

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Midterm results of edge-to-edge mitral valve repair without annuloplasty. Eighty-third Annual Meeting of The American Association for Thoracic Surgery Boston, Mass., May 4-7, 2003. Abstract Book.

26. A novel technique for correction of severe tricuspid valve regurgitation due to complex lesions. De Bonis M, Lapenna E, La Canna G, Grimaldi A, Maisano F, Torracca L, Caldarola A, Alfieri O. 2nd EACTS/ESTS Joint Meeting , Vienna 12-15 October 2003 Book of Abstracts page 680 (Abstract n. 295)

27. The edge-to-edge technique in mitral valve repair O. Alfieri, M. De Bonis. 34th Annual Meeting of the Japanese Society for Cardiovascular Surgery Tokyo 18-20 February , 2004. Abstract Book

28. The Acorn Cardiac Support Device (CSD); patient functional status. Albanese MC, Livi U, Tursi V, Franco-Cereceda A, Vitali E, Russo C, Frigerio M, Alfieri O, De Bonis M, Fragasso G. AMNCO 2004, XXXV Congresso Nazionale di Cardiologia, Firenze 22-26 Maggio 2003 Atti del Congresso

29. Minimally invasive mitral valve repair as a routine approach in selected patients. Torracca L, Lapenna E, De Bonis M, Kassem S, La Canna G, Crescenzi G, Castiglioni A, Alfieri O. XXII Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2004, Bologna (Abstract n.11, Abstract Book pag. 93)

30. Long-term results of the edge-to-edge technique for the treatment of the anterior mitral leaflet prolapse. De Bonis M, Lapenna E, La Canna G, Torracca L, Maisano F, Alfieri O. Regesta T, Castiglioni A. XXII Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2004, Bologna (Abstract DIP 18, Abstract Book pag. 172)

31. Initial clinical experience with a magnetic system for distal coronary artery anastomoses in CABG. Lapenna E, Torracca L, De Bonis M, Castiglioni A, Vigano G, Arcobasso L, Alfieri O, Pappalardo F. XXII Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2004, Bologna (Abstract V7, Abstract Book pag. 325)

32. Spinal cord stimulations i san effective treatment for no-option patients with refractory angina and previous CABG. Lapenna E, Rapati D, Lullo F, Cardano P, De Bonis M, Zangrillo A, Alfieri O. XXII Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2004, Bologna (Abstract DIP 58, Abstract Book pag. 212)

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33. Mitral valve repair in functional mitral regurgitation due to end-stage dilated cardiomyopathy. De Bonis M, Lapenna E, La Canna G, Ficarra E, Verzini A, Torracca L, Malsano F, Alfieri O. XXII Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2004, Bologna (Abstract P 33, Abstract Book pag. 259)

34. Rescue edge-to-edge technique in case of suboptimal result of conventional mitral valve repair. De Bonis M, Lapenna E, Kassem S, Ziskind Z, Torracca L, Malsano F, La Canna G, Alfieri O. XXII Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2004, Bologna (Abstract P 50, Abstract Book pag. 276)

35. Mitral valve repair for functional mitral regurgitation in end-stage dilated cardiomyopathy: the role of the “edge-to-edge” technique. M. De Bonis, E. Lapenna, G. La Canna, E. Ficarra, M. Pagliaro, L. Torracca, F. Maisano, O. Alfieri. 2004 Meeting of the American Heart Association November 7-10, 2004. New Orleans, Louisiana, USA Supplement to Circulation vol 110, No 17, Abstract n. 1992.

36. Similar long-term results of mitral valve repair for anterior compared to posterior leaflet prolapse. M. De Bonis, R. Lorusso, E. Lapenna, S. Kassem, G. De Cicco, L. Torracca, F. Maisano, G. La Canna, O. Alfieri. The Western Thoracic Surgical Association Annual Meeting, June 22-25, 2005, Victoria, Canada

37. Repair of secondary mitral valve regurgitation O. Alfieri, M. De Bonis Book of proceedings of the Post-graduate Course on Adult Cardiac Surgery. 4th EACTS/ESTS Joint Meeting 24-28 September 2005, Barcelona, Spain.

38. The Edge-to-Edge Mitral Valve Repair: Indications, Technique and Long- Term Results O. Alfieri, MD, M. De Bonis, MD. Book of proceedings of the Advanced Cardiac Techniques in Surgery 2006. New York (USA), 24-25 April, 2006

39. Recurrence of mitral regurgitation parallels the absence of left ventricular reverse remodeling after mitral repair in advanced dilated cardiomyopathy. M. De Bonis, E. Lapenna, A. Verzini, G. La Canna, A. Grimaldi, L. Torracca, F. Maisano, O. Alfieri. 5th EACTS/ESTS Joint Meeting, Stockholm, Sweden, 9-13 September 2006. Abstract book

40. Preliminary experience with the geoform annuloplasty ring for the surgical treatment of functional mitral regurgitation in advanced dilated cardiomyopathy. M. De Bonis, E. Lapenna, F. Maisano, L. Torracca, A. Mignatti, A. Grimaldi, G. La Canna, O. Alfieri.

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XXIII Congresso della Società Italiana di Chirurgia Cardiaca, 2-5 Dicembre 2006, Fiera di Roma, Roma (Abstract ID 28808, Abstract Book pag. 30)

41. The Clover technique for correction of severe tricuspid valve regurgitation due to complex lesions. E. Lapenna, M. De Bonis, F. Sorrentino, A. Verzini, A. Grimaldi, L. Torracca,

F. Maisano, O. Alfieri. XXIII Congresso della Società Italiana di Chirurgia Cardiaca, 2-5 Dicembre 2006, Fiera di Roma, Roma (Abstract ID 28869, Abstract Book pag. 35)

42. Surgical treatment in hypertrophic obstructive carciomyopathy. A. Verzini, G. La Canna, E. Capritti, L. Torracca, F. Maisano, A. Castiglioni, M.

De Bonis, O. Alfieri. XXIII Congresso della Società Italiana di Chirurgia Cardiaca, 2-5 Dicembre 2006, Fiera di Roma, Roma (Abstract ID 28760, Abstract Book pag. 69)

43. Evolution of tricuspid regurgitation after mitral valve repair for functional mitral regurgitation in dilated cardiomyopathy M. De Bonis, E. Lapenna, F. Sorrentino, G. La Canna, A. Grimaldi, F. Maisano, L. Torracca, O. Alfieri. 21st EACTS Annual Meeting, Geneva, 15-19 September 2007 Book of Abstracts

44. Mitral valve surgery in emergency for severe acute regurgitation: analysis of postoperative outcome from a multicentre study. R. Lorusso, S. Gelsomino, G. De Cicco, C. Russo, A. Colli, M. De Bonis, C. Beghi, J.L. Pomar. 21st EACTS Annual Meeting, Geneva, 15-19 September 2007 Book of Abstracts

45. Cardiac Resynchronization Therapy (CRT) in patients candidate to open- chest Cardiac Surgery A. Barosi, A. Sacco, C. Pappone, M. De Bonis, G. Speca, A. Mazzola, C. D. Dicandia, G. Esposito, A. Della Scala, T. Marotta and M. Lunati XIII World Congress on Cardiac Pacing and Electrophysiology, 2008

46. Cardiac resynchronization therapy in candidates to open-chest cardiac surgery Barosi A, Sacco A, Speca G, Mazzola A, Paglino G, De Bonis M, Iacopino S, Cassese M, Dicandia CD, Esposito G. European Journal of Heart Failure Supplements, Volume 7, Issue Supplement S1, pages 182–183, 2008.

47. Critical analysis of transcatheter mitral valve repair. O. Alfieri, M. De Bonis. Postgraduate Course of the European Association of Cardiothoracic Surgery Meeting, 13-17 September 2008, Lisbon (Portugal). Postgraduate Course Book.

48. Undersized annuloplasty for functional mitral regurgitation: is it responsible for clinically relevant mitral stenosis during exercise?

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A. Grimaldi, M. De Bonis, G. La Canna, A. Verzini, D. Ferrara, A. Galanti, M.C. Calabrese, O. Alfieri. 23rd European Association for Cardiothoracic Surgery Meeting, Vienna, Austria, 17-21 October 2009. Book of Abstracts

49. Improved surgical results in complex tricuspid valve insufficiency. E. Lapenna, M. De Bonis, A. Verzini, G. La Canna, D. Ferrara, M.C. Calabrese, M. Taramasso, O. Alfieri. 23rd European Association for Cardiothoracic Surgery Meeting, Vienna, Austria, 17-21 October 2009. Book of Abstracts

50. The geoform annuloplasty ring for the surgical treatment of functional mitral regurgitation in advanced dilated cardiomyopathy. De Bonis M., Grimaldi A, Maisano F, Taramasso M, Lapenna E, La Canna G, Galanti A, Alfieri O American Heart Association Scientific Session 2009, Novembre 15-17, 2009 Orlando, Florida, USA (Abstract n.3242)

51. Mitral repair for functional mitral regurgitation in idiopathic dilated cardiomyopathy: improved outcome with ablation of atrial fibrillation and/or resynchronization therapy. De Bonis M, Taramasso M, Galanti A, Benussi S, Lapenna E, Kieser T, Grimaldi A, Alfieri O. American Heart Association Scientific Session 2009, Novembre 15-17, 2009. Orlando, Florida, USA (Abstract n. 3681)

52. The Geoform ring: mechanism specific therapy for ischemic and myopathic mitral regurgitation. S. Bolling, R. Damiano, F. Maisano, M. De Bonis, O Alfieri. American Heart Association Scientific Session 2009, Novembre 15-17, 2009. Orlando, Florida, USA (Abstract n. 3382).

53. De Bonis M, Taramasso M, Grimaldi A, Maisano F, Calabrese MC, Verzini A, Ferrara D, Alfieri O. The GeoForm annuloplasty ring for the surgical treatment of functional mitral regurgitation in advanced dilated cardiomyopathy. 24th EACTS Annual Meeting, Geneva, Switzerland, 11-15 September 2010. Interactive Cardiovascular and Thoracic Surgery 2010; 11(suppl 2):S65.

54. Russo C, Gelsomino S, Santini F, Livi U, Renzulli A, Mariscalco G, De Bonis M, Pacini D, Vitale N, Lorusso R. Italian multicenter study on acute aortic dissection: a preliminary report on a 36-year retrospective evaluation of postoperative results in 1789 patients. XXV Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2010, Hotel Rome Cavalieri, Roma (Abstract ID 3, Abstract Book pag. 3).

55. Lorusso R, Russo C, Livi U, Lucà F, Carella R, Mariscalco G, Renzulli A, De Bonis M, Borghetti V, Gelsomino S. Emergency surgery in patients with acute native mitral valve endocarditis: true impact of septic and cardiogenic shock on early and late outcome.

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XXV Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2010, Hotel Rome Cavalieri, Roma (Abstract ID 99, Abstract Book pag. 5).

56. Ferrara D, Taramasso M, Calabrese MC, Verzini A, Lapenna E, Grimaldi, De Bonis M, Alfieri O. Mitral valve replacement or repair for functional mitral regurgitation in advanced dilated cardiomyopathy: is it really the same? XXV Congresso della Società Italiana di Chirurgia Cardiaca, 6-9 Novembre 2010, Hotel Rome Cavalieri, Roma (Abstract ID 299, Abstract Book pag. 57)

57. Gerosa G. Di Giammarco G, Sani G, Maccherini M, Rinaldi M, De Bonis M, Gazzoli F, Renzulli A, Mazzesi G, Di Credico G, Zogno M, Livi U. The use of post auricular pedestal is a winning strategy in reducing driveline infections during long-term mechanical support with LVADs. Thirty-first Annual Meeting and Scientific Sessions April 13-16, 2011, San Diego, California, USA J Heart Lung Transplantation 2011;30(4):S94 (Abstract n. 267)

58. De Bonis M., Alfieri O. Edge-to-edge double orifice valvuloplasty: when does it fit? 21st Word Congress of the World Society of Cardiothoracic Surgeons Berlin, Germany, 12-15 June 2011 Congress proceedings book

59. De Bonis M, Ferrara D, Taramasso M, Calabrese MC, Verzini A, Dorigo E, Buzzati N, Alfieri O. Mitral valve replacement or repair for functional mitral regurgitation in advanced dilated cardiomyopathy: is it really the same? 25th European Association for Cardiothoracic Surgery Meeting, Lisbon, Portugal, 1-5 October 2011. Book of Abstracts

60. De Bonis M, Lapenna E, Manca M, Calabrese MC, Taramasso M, La Canna G, Buzzati N, Alfieri O. Mid-term results of tricuspid annuloplasty with a three-dimensional remodeling ring. 25th European Association for Cardiothoracic Surgery Meeting, Lisbon, Portugal, 1-5 October 2011. Book of Abstracts

61. De Bonis M, Taramasso M, Verzini A, Ferrara D, Lapenna E, Calabrese MC, Grimaldi A, Alfieri O. Long-term results of mitral repair for functional mitral regurgitation in idiopathic dilated cardiomyopathy. 25th European Association for Cardiothoracic Surgery Meeting, Lisbon, Portugal, 1-5 October 2011. Book of Abstracts

62. Giacomini A, Taramasso M, De Bonis M, Denti P, La Canna G, Colombo A, Alfieri O, Maisano F. Surgical versus percutaneous treatment of functional mitral regurgitation.

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25th European Association for Cardiothoracic Surgery Meeting, Lisbon, Portugal, 1-5 October 2011. Book of Abstracts

63. V. Tarzia, U. Livi, G. Di Giammarco, G. Sani, M. Maccherini, M. Rinaldi, F. Alamanni, M. De Bonis, F. Gazzoli, A. Renzulli, G. Mazzesi, G. Arpesella, G. Di Credico, M. Zogno, A. Costantino, G. Gerosa. Low Infection Rates in Jarvik 2000 LVAD. Are Post-Auricular Cable and Pump Configuration Playing a Positive Effect? 32nd Annual Meeting & Scientific Sessions of the ISHLT Journal of Heart and Lung Transplantation vol. 31 issue 4 April, 2012. p. S175 DOI: 10.1016/j.healun.2012.01.513. ISSN: 1053-2498. Prague April 18-21, 2012 Abstract n. 501

64. De Bonis M, Lapenna E, Lorusso R, Buzzati N, Gelsomino S, Taramasso M, Vizzardi E, Alfieri O. Very long-term results (up to 17 yrs) with the double orifice mitral valve repair associated to ring annuloplasty for degenerative mitral regurgitation 92nd Annual Meeting of the American Association for Thoracic Surgery, April 28-May 2, 2012 San Francisco, CA, USA. Book of AATS Meeting abstract

65. Tarzia V, Bottio T, Livi U, Maiani M, Di Giammarco G, Sani G, Maccheroni M, Rinaldi M, Alemanni F, De Bonis M, Gazzoli F, Renzulli A, Arpesella G, Gerosa G. Age is no boundary to long term survival on permanent MCS: a multicentre experience. 33rd Annual Meeting and Scientific Sessions ISHLT , Montreal, Canada, April 24-27, 2013. Poster Session 3, Abstract Number: 851594

66. De Bonis M, Lapenna E, Buzzatti N, Taramasso M, Calabrese MC, Nisi T, Pappalardo F, Alfieri O. Can the edge-to-edge technique provide durable results when used to rescue patients with suboptimal conventional mitral repair? Abstract in Interactive Cardiovascular and Thoracic Surgery 2012 (supplement)

67. De Bonis M, Lapenna E, Taramasso M, Calabrese MC, Buzzati N, Pozzoli A, Nisi T, Alfieri O. Is commissural closure for the treatment of mitral regurgitation durable? A long- term (up to 15 years) clinical and echocardiographic study. 26th EACTS Annual Meeting, Barcelona, Spain, 27-31 October 2012. Abstract in Interactive Cardiovascular and Thoracic Surgery 2012 (supplement)

68. De Bonis M, Lapenna E, Buzzatti N, Alfieri O. The Valve Is Still Leaking After Repair: One Stitch More To Fix It? AATS Mitral Conclave Hilton New York, Avenue of the Americas, New York, NY, USA May 3, 2013 Abstact book

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69. De Bonis M. Supporti meccanici al circolo: campo di applicazione dei diversi tipi di device. VAD-EMECUM: conoscere e gestire i VAD. 47° Convegno Cardiologia 2013. Milan 23-27 September 2013.

70. De Bonis M, Calabrese M, La Canna G, Lapenna E, Nisi T, Di Giannuario G, Alati E, Alfieri O. Prophylactic tricuspid annuloplasty in patients with dilated tricuspid annulus undergoing mitral surgery for degenerative mitral regurgitation: an interim analysis of a prospective randomized study. 27th EACTS Annual Meeting, Vienna, Austria, 4-9 October 2013. Abstract in Interactive Cardiovascular and Thoracic Surgery 2013;17(supplement2), S137 (Abstract n. 279).

71. De Bonis M, Lapenna E, La Canna G, Buzzatti N, Taramasso M, Pappalardo F, Calabrese M, Alfieri O. Very long-term durability of the edge-to- edge repair for isolated anterior mitral leaflet prolapse: up to 21 years clinical and echocardiographic results. 27th EACTS Annual Meeting, Vienna, Austria, 4-9 October 2013. Abstract in Interactive Cardiovascular and Thoracic Surgery 2013;17(supplement2), S112 (Abstract n. 177).

72. Buzzatti N, Iaci G, Taramasso M, Nisi T, Lapenna E, De Bonis M, Maisano F, Alfieri. Long-term outcomes (up to 16 years) of tricuspid valve replacement after previous left-sided heart surgery. 27th EACTS Annual Meeting, Vienna, Austria, 4-9 October 2013. Abstract in Interactive Cardiovascular and Thoracic Surgery 2013;17(supplement2), S112 (Abstract n. 177).

73. De Bonis M, Lapenna E, Maisano F, La Canna G, Buzzatti N, Pappalardo F, Calabrese M, Nisi T, Alfieri O. Long-term results (up to 18 years) of the edge-to-edge mitral valve repair without annuloplasty in degenerative mitral regurgitation: implications for the percutaneous approach. American Heart Association Scientific Session 2013, Novembre 16-20, 2013. Dallas, Texas, USA Session Title: William W. L. Glenn Lecture and Surgical Therapy for Valvular Heart Disease II Circulation 2013;128: issue 22 supplement (Abstract n. 11496).

74. Taramasso M, Maisano F, Denti P, Pozzoli A, Buzzatti N, De Bonis M, La Canna G, Alfieri O. Surgical treatment of paravalvular leak: long-term results in a single center experience (up to 14 years). Session title: Minimally invasive mitral valve surgery. 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014. Interactive Cardiovascular and Thoracic Surgery 2014;19 (suppl.1). Abstract 093

75. De Bonis M, Taramasso M, Lapenna E, Denti P, La Canna G, Pappalardo F, Cioni M, Alfieri O. Mitraclip therapy and surgical edge-to-edge repair in patients with severe left ventricular dysfunction and secondary mitral regurgitation: mid-term results of a single center experience.

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Session title: Re-evaluation of mitral valve repair and replacement. 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014. Interactive Cardiovascular and Thoracic Surgery 2014;19 (suppl.1). Abstract 142

76. Taramasso M, Maisano F, Denti P, Latib A, De Bonis M, La Canna G, Colombo A, Alfieri O. Clinical and anatomical predictors of mitraclip therapy failure for functional mitral regurgitation. Session title: Part II: Catheter based mitral interventions: the mitral going transcutaneous. 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014. Interactive Cardiovascular and Thoracic Surgery 2014;19 (suppl.1). Abstract 211

77. Buzzatti N, Denti P, Schiavi, Taramasso M, De Bonis M, Di Giannuario G, La Canna G, Alfieri O. Midterm outcomes (over three years) of percutaneous mitral repair in the real world: a sincle center experience. Session title: Part II: Catheter based mitral interventions: the mitral going transcutaneous. 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014. Interactive Cardiovascular and Thoracic Surgery 2014;19 (suppl.1). Abstract 212

78. Untreated mild to moderate tricuspid regurgitation in dilated cardiomyopathy patients submitted to mitral repair: what happens at long term? De Bonis M, Lapenna E, Nisi T, Giacomini A, Calabrese M, Miceli A, Alfieri O, Glauber M Session title: The tricuspid a continuing problem 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014. Interactive Cardiovascular and Thoracic Surgery 2014;19 (suppl.1). Abstract 216

79. Prognostic impact and late evolution of untreated moderate functional tricuspid regurgitation in patients undergoing aortic valve replacement. Taramasso M, De Bonis M, Pozzoli A, Schiavi D, Latib A, Buzzatti N, La Canna G, Alfieri O. Session title: The tricuspid a continuing problem 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014. Interactive Cardiovascular and Thoracic Surgery 2014;19 (suppl.1). Abstract 221

80. Lorusso R, Barili F, Miceli A, Parolari A, Alamanni F, De Vincentiis C, Aimè E, Nicolini F, Gherli T, Colli A, De Bonis M, Paglino G, Della Bella P, Actis Dato G, Casabona R, Sponga S, Livi U, Mariscalco G, Beghi C, Scrofani R, Antona C, Tritto FP, Gerosa G, Piazza L, Villa E, Troise G, Serraino F, Renzulli A, Rosato F, Grossi C, Paparella D, Amorese L, Vizzardi E, Solinas M, Glauber M. Permanent Pacemaker Implantation Following Heart Surgery: In-Hospital and Postoperative Retrospective Multicentre Evaluation in 1,156 Implants. American Heart Association Scientific Session 2014

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Circulation 2014; (Abstract n. 20130 ).

81. Veno-arterial ECMO for fulminant myocarditis in adult patients: a multi- institutional experience. R. Lorusso; P. Centofanti; C. Russo; S. Gelsomino; L. Botta; M. Actis Dato; R. Casabona; L. Martinelli; G. Casali; F. Musumeci; F. Pappalardo; M. De Bonis; A. Zangrillo; O. Alfieri; C. Pellegrini; S. Mazzola; G. Coletti; E. Vizzardi; R. Bianco; G. Gerosa; M. Massetti;F. Caldaroni; E. Pilato; D. Pacini; R. Di Bartolomeo; G. Mariscalco;C. Beghi; A. Miceli; M. Glauber; S. Sponga; U. Livi; M. Rinaldi. Giornale Italiano di Cardiologia 2014 (volume Dicembre 2014: abstract C157).

82. Preliminary Results from ITAMACS, the ITAlian multi center registry for Mechanically Assisted Circulatory Support. G. Feltrin, M. Frigerio, L. Martinelli, M. De Bonis, M. Rinaldi, M. Pilato, F. Musumeci, G. Faggian, U. Livi, M. Maccherini, A. Iacovoni, A. Barbone, G. Di Giammarco, C. Maiello, G. Marinelli, F. Alamanni, G. Ambrosio, A. Grimaldi, G. Leonardi, F. Pagani, M. Massetti, L. Rizzato, G. Gerosa, A. Nanni Costa. Control/Tracking Number: 2015-A-2903-ISHLT 35th Annual Meeting of the International Society for Heart and Lung Transplantation Nice, France, 3-15th April 2015 Abstract book

83. A Multicenter Propensity-score Analysis Of 991 Patients With Severe Aortic Stenosis And Intermediate-high Risk Profile: Conventional Surgery versus Sutureless Valves versus TAVR Claudio Muneretto, Ottavio Alfieri, Michele De Bonis, Roberto Di Bartolomeo, Gianluigi Bisleri, Carlo Savini, Gianluca Folesani, Lorenzo Di Bacco, Manfredo Rambaldini, Juan Pablo Maureira, Francois Laborde, Maurizio Tespili, Alberto Repossini, Thierry A Folliguet. 95th Annual Meeting of the American Association for Thoracic Surgery, April 25-29, 2015 Seattle, WA, USA. Book of AATS Meeting abstract

84. What is a "good" result after transcatheter mitral repair? Impact of 2+ residual mitral regurgitation. Nicola Buzzatti, Michele De Bonis, Paolo Denti, Elisabetta Lapenna, Fabio Barili, Giovanna Di Giannuario, Giovanni La Canna, Ottavio Alfieri. 95th Annual Meeting of the American Association for Thoracic Surgery, April 25-29, 2015 Seattle, WA, USA. Book of AATS Meeting abstract

85. Which is the optimal strategy for patients with severe aortic stenosis and intermediate-high risk profile? A multicenter propensity-score analysis in 991 consecutive patients Muneretto C, De Bonis M, Bisleri G, Alfieri O, Di Bartolomeo R, Rambaldini M, Maureira JP, Laborde F, Tespili M, Folliguet T. Session: Percutaneous versus surgical management of valvular aortic stenosis: boundaries versus opportunities FP Number: 6021. Session Type: Rapid Fire Abstract 2015 European Society of Cardiology Congress

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29 August - 2 September 2015, London - United Kingdom Abstract book

86. Thromboembolic complications after left ventricular assist device implantation is associated with platelet activation as measured via the Platelet Activity State assay' L. Valerio, F. Consolo, M. De Bonis, D. Bluestein, P. Tran, M. Slepian, A. Redaelli, F. Pappalardo. 29th EACTS Annual Meeting, 3-7 October 2015, Amsterdam, The Netherlands. Abstract book

87. Long-term results of mitral repair in patients with severe left ventricular dysfunction and secondary mitral regurgitation: does the technique matter? M. De Bonis, E. Lapenna, T. Nisi, M. Calabrese, F. Pappalardo, A. Pozzoli, G. La Canna, O. Alfieri 29th EACTS Annual Meeting, 3-7 October 2015, Amsterdam, The Netherlands. Abstract book

88. Optimal results immediately after Mitraclip or surgical edge-to-edge for functional mitral regurgitation: are they really stable at 4 years?' M. De Bonis, E. Lapenna, N. Buzzatti, G. La Canna, P. Denti, D. Schiavi, F. Pappalardo, O. Alfieri. 29th EACTS Annual Meeting, 3-7 October 2015, Amsterdam, The Netherlands. Abstract book

89. Does transcatheter aortic valve replacement improve outcomes compared to surgery in patients with severe aortic stenosis and renal dysfunction? A propensity matched study C. Muneretto, O. Alfieri, M. De Bonis, A. Repossini, L. Di Bacco, R. Di Bartolomeo, G. Bisleri, T. Folliguet. 29th EACTS Annual Meeting, 3-7 October 2015, Amsterdam, The Netherlands. Abstract book

90. MitraClip repair is associated with better survival compared to heart-failure models predictions in functional mitral regurgitation N. Buzzatti, P. Denti, D. Schiavi, L. Vicentini, M. De Bonis, G. La Canna, M. Senni, O. Alfieri. 29th EACTS Annual Meeting, 3-7 October 2015, Amsterdam, The Netherlands. Abstract book

91. A Comparison Between New Generation And First Generation Transcatheter Aortic Valve Implantation (TAVI) Devices: A Single Centre Experience Neil Ruparelia, Azeem Latib Francesco Giannini, Filippo Figini, Nicola Buzzatti, Antonio Mangieri, Damiano Regazzoli, Stefano Stella, Alessandro Sticchi, Eustachio Agricola, Michele De Bonis, Fabrizio Monaco, Pietro Spagnolo, Alaide Chieffo, Matteo Montorfano, Ottavio Alfieri, Antonio Colombo Transcatheter Cardiovascular Therapeutics (TCT)

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San Francisco (USA), October 11-15, 2015 Abstract book TCT-666

92. Patient and Healthcare System Benefits of Contemporary Transcatheter Aortic Valve Implantation (TAVI) Practice Neil Ruparelia, Azeem Latib, Francesco Giannini, Filippo Figini, Nicola Buzzatti, Antonio Mangieri, Damiano Regazzoli, Stefano Stella, Alessandro Sticchi, Eustachio Agricola, Michele De Bonis, Fabrizio Monaco, Pietro Spagnolo, Alaide Chieffo, Matteo Montorfano, Ottavio Alfieri, Antonio Colombo Transcatheter Cardiovascular Therapeutics (TCT) San Francisco (USA), October 11-15, 2015 Abstract book TCT-154

93. Systolic Anterior Motion and Mitral Valve Repair: A Predicting Computational Model P. Denti, A. Geretto, L. Vicentini, N. Buzzatti, A. Pozzoli, F. Monaco, M. De Bonis, O. Alfieri. 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain Published on line at: medialibrary.eacts.cyim.com/

94. Long-term results (up to 14 years) of the clover technique for the treatment of complex tricuspid valve regurgitation Michele De Bonis, Elisabetta Lapenna, Stefania Di Sanzo, Benedetto Del Forno, Alessandro Castiglioni, Alberto Pozzoli, Ilaria Giambassi, Ottavio Alfieri. 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain Published on line at: medialibrary.eacts.cyim.com/

95. Minimally invasive or conventional edge-to-edge repair for severe mitral regurgitation due to bileaflet prolapse in Barlow’s disease: does the surgical approach have an impact on the long-term results? M. De Bonis, E Lapenna, B. Del Forno, S.Di Sanzo, A. Giacomini, F. Pappalardo, G. La Canna, O. Alfieri. 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain Published on line at: medialibrary.eacts.cyim.com/

96. Long-term outcomes of concomitant surgical ablation of atrial fibrillation in patients undergoing cardiac surgery for hypertrophic cardiomyopathy E. Lapenna, M. De Bonis, A. Pozzoli, S. Nascimbene, G. La Canna, S. Di Sanzo, T. Nisi, O. Alfieri. 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain Published on line at: medialibrary.eacts.cyim.com/

97. Second pump run after mitral repair in contemporary practice: when,why,worthy?

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M. De Bonis, E. Lapenna, I. Giambuzzi, R. Meneghin, G. Affronti, F. Pappalardo, A. Castiglioni, C. Trumello, N. Buzzatti, A. Giacomini, M. Raimondi Lucchetti, O. Alfieri 31st EACTS Annual Meeting 7-11 October 2017, Vienna Published on line at: medialibrary.eacts.cyim.com/

98. 1-year evolution of tricuspid regurgitation after transcatheter mitral repair. N. Buzzatti, P. Denti, D. Schiavi, G. La Canna, I. Scarfo’, L. Vicentini, M. De Bonis, O. Alfieri. 31st EACTS Annual Meeting 7-11 October 2017, Vienna Published on line at: medialibrary.eacts.cyim.com/

99. Durability at 20 years of quadrangular resection with annular plication for mitral regurgitation due to posterior leaflet prolapse: the paradox of being a benchmark out of fashion. E. Lapenna, M. De Bonis, L. Amore, B. Del Forno, G. La Canna, G. Iaci, A. Giacomini, D. Schiavi, L. Vicentini, M. Bargagna, I. Belluschi, S. Gulletta, O.Alfieri 31st EACTS Annual Meeting 7-11 October 2017, Vienna Published on line at: medialibrary.eacts.cyim.com/

100. Left ventricular reverse remodeling after mitral valve repair for degenerative posterior leaflet prolapse: does it affect durability of chordal implantation repair? B. Del Forno, E. Lapenna, F. Monaco, I. Giambuzzi, M. De Bonis, O. Alfieri 31st EACTS Annual Meeting 7-11 October 2017, Vienna Published on line at: medialibrary.eacts.cyim.com/

101. Prediction of systolic anterior motion after mitral valve repair: virtual posterior leaflet resection associated with ring annuloplasty. P. Denti, A. Geretto, A. Pozzoli, F. Monaco, L. Vicentini, N. Buzzatti, M. De Bonis, O. Alfieri 31st EACTS Annual Meeting 7-11 October 2017, Vienna Published on line at: medialibrary.eacts.cyim.com/

Invited lectures/Presentations without published abstracts

1. Chirurgia cardiaca e danno cerebrale M. De Bonis, O. Alfieri Ruolo del cuore nella patogenesi ischemica cerebrale. San Raffaele University, Milan, 23 January 2004.

2. Lettura magistrale: nuove opzioni chirurgiche per il cuore scompensato. M. De Bonis, O. Alfieri Nuove Frontiere in Cardiologia. 5° Corso di aggiornamento in Cardiologia.

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Caprile (BL), 17-19 Settembre 2004.

3. Surgery for chronic heart failure in valve disease patients. M. De Bonis, O Alfieri. Heart Failure 2005 Meeting of the European Society of Cardiology Lisbon, Portugal, 11-14 June 2005

4. Tricuspid insufficiency : techniques of repair. M. De Bonis (member of the faculty) 7th Mitral reconstruction surgery symposium. San Raffaele Hospital, Milano 17-18 October 2005

5. Risultati della rivascolarizzazione chirurgica del miocardio ibernato. M. De Bonis New Horizons in Cardiovascular Medicine: arrhythmias, coronary interventions, echocardiography and genetics Portonovo (Ancona), november 4th-5th 2005

6. Surgical treatment of functional mitral insufficiency. M. De Bonis International school of cardiac surgery. 1st course: interactive approach to cardiac surgery Erice, 15th-19th Novembre 2005

7. La chirurgia riparativa della valvola mitrale. Le indicazioni estreme: fase tardiva. M. De Bonis. Nuove frontiere nella diagnostica e terapia cardiovascolare. Dalla fisiologia clinica alla biologia clinica (3° ed.). Baveno, April 27th-28th 2006.

8. Ruolo della Cardiochirurgia nel trattamento dell’insufficienza mitralica da disfunzione del ventricolo sinistro M. De Bonis Temi di Cardiologia. 6-8 Ottobre 2006, Hotel Airone, Portoferraio, Isola d’Elba

9. Insufficienza mitralica e cardiomiopatia. M. De Bonis M.I.T.R.A.L.E Meeting II 26-28 Ottobre 2006, Università Vita e Salute San Raffaele, Milano

10. Mechanisms of mitral valve dysfunction in ischemic and dilated cardiomiopathy. M. De Bonis Training Course in Cardiac Surgery entitled: Mitral valve repair in ischemic and dilated cardiomiopathy. 56th European Society for Cardio-Vascular Surgery International Congress Venice, Italy, Lido Casino Palace, May 17-20, 2007

11. L’insufficienza tricuspidalica nella cardiomiopatia dilatativa. M. De Bonis

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Chirurgia della valvola tricuspide: quando, come, perché. 15 Giugno 2007, Università Vita e Salute San Raffaele, Milano

12. L’intervento combinato del CRT e della cardiochirurgia. M. De Bonis L’ecocardiografia e le altre metodiche di imaging nello scompenso cardiaco: dal caso clinico alla flow chart. Brisighella, Terme di Brisighella 21-23 Giugno, 2007

13. L’intervento combinato del CRT e della cardiochirurgia. M. De Bonis L’ecocardiografia e le altre metodiche di imaging nello scompenso cardiaco: dal caso clinico alla flow chart. Bolzano, Hotel Alpi, 25-27 Ottobre, 2007

14. La chirurgia dello scompenso cronico o recidivante. Casi clinici e discussione. M. De Bonis Dalla Evidence-Based Medicine alle cure “su misura”. Il ruolo insostituibile della clinica nella pratica e nella ricerca cardiovascolare. Baveno, 15-16 Novembre 2007

15. La terapia anticoagulante nel paziente cardiochirurgico. M. De Bonis Convegno diabete e coagulazione. Università Vita e Salute San Raffaele, Ospedale San Raffaele, Milano 17 Maggio 2008.

16. L’insufficienza tricuspidalica nella cardiomiopatia dilatativa. M. De Bonis Meeting “La valvola tricuspide: still a forgotten valve?” Università Vita e Salute San Raffaele, Milano, 24 Ottobre 2008.

17. L’insufficienza tricuspidale dopo chirurgia dell’insufficienza mitralica funzionale/ischemica. M. De Bonis MITRALE III. 3° Meeting Italiano Tecniche Riparative Avanzate Live Ecocardiografia. Centro Congressi San Raffaele, Milano, 20-22 Novembre 2008.

18. La mitrale ischemica: sostituzione o riparazione: M. De Bonis Romanestesia. Sesto incontro romano di cardioanestesia. Hotel Sheraton Golf, Roma 26-28 Novembre 2009.

19. Surgical treatment of mitral regurgitation: when and how? M. De Bonis Rome Cardiology Forum 2010, A European Society of Cardiology Update Programme in Cardiology Rome, Italy, May 12-14 2010

20. Fisiologia ed evoluzione dei VAD: dal flusso pulsatile al flusso continuo

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M. De Bonis Corso di aggiornamento AMNCO, Niguarda Hospital, Milan, 25th April, 2011

21. La chirurgia conservativa della valvola mitrale M. De Bonis 2° Corso di Perfezionamento su “Formazione clinica, comunicazione, management in Cardiologia”. Anno Accademico 2010-2011. Seminario interattivo di Cardiologia Clinica: “I trattamenti estremi in cardiologia”, Verbania Pallanza 26-28 Maggio 2011

22. New therapies for mitral regurgitation. Surgical strategies. M. De Bonis European Society of Cardiology Congress 2011 Paris, France 30 August 2011.

23. Wait and see versus early operation (Guidelines ACC/AHA/ESC) M. De Bonis 2° Kardiochiururgisches Sonnenberg Symposium Mitralklappeninsuffizienz. Wie, wann, warum behandeln? Sonnenberg Convention Center, Zurich, 8 September 2011

24. Understanding mitral regurgitation in heart failure – do you? M. De Bonis Focus session on functional mitral regurgitation. 25th European Association for Cardiothoracic Surgery Meeting, Lisbon, Portugal, 3 October 2011.

25. Un ponte verso il trattamento dello scompenso: l’ambulatorio integrato orientato alle opzioni chirurgiche avanzate. M. De Bonis Congresso “Verso un approccio integrato al paziente affetto da aritmie ventricolari. Istituto Scientifico Universitario San Raffaele, Milano, 20-21th October 2011

26. When to treat tricuspid regurgitation? M. De Bonis Sess. Title : Tricuspid regurgitation: dark side of the regurgitations EUROECHO & other Imaging Modalities 2011, Budapest, Hungary, 9 December 2011

27. Moderate tricuspid regurgitation at the time of left-sided valve surgery. M. De Bonis Sess. Title : The difficult patient with multiple valve disease EUROECHO & other Imaging Modalities 2011, Budapest, Hungary, 10 December 2011

28. Assistenza ventricolare meccanica 2012. Qual’è il paziente più difficile da gestire. M. De Bonis. Convention Centri Scompenso Lombardia. Update scientifico-organizzativo. Villa Fenaroli Palace Hotel Rezzato (Brescia), 4 May, 2012

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29. Functional mitral regurgitation: medical therapy, surgical or percutaneous repair? M. De Bonis Joint E.A.E./S.I.E.C. teaching course update in valvular heart diseases: from clinical imaging to therapeutic innovations. San Raffaele Congress Center, Milan, Italy, May 8th-9th, 2012

30. Dosing and management of bivalirudin for ecmo: preliminary experience. Agracheva N, Pieri M, Bonaveglio E, Scandroglio AM, De Bonis M, Melisburgo G, Pappalardo F. Euro-ELSO 1st Congress - Rome, May 11th-13th, 2012

31. HVAD Surgical Techniques: thoracotomy M. De Bonis HeartWare Regional User Meeting 2012 24-25 th June, 2012, Grand Hotel Villa Torretta, Sesto San Giovanni, Milan

32. Mitral repair in asymptomatic patients. M. De Bonis Session Title: Controversies in valvular heart surgery. European Society of Cardiology Congress 2012, Munich, Germany, 28 August 2012

33. Quando e come eseguire la correzione dell’insufficienza mitralica. M. De Bonis Seminario “La patologia delle valvole cardiache: i nuovi scenari della diagnosi e della terapia”. Aula Pinta-Dibit 1, Università Vita-Salute San Raffaele, Milano, 20 April 2013

34. Optimizing Outcomes in ischemic mitral regurgitation. M.De Bonis AATS Mitral Conclave Hilton New York, Avenue of the Americas, New York, NY, USA May 2-3, 2013

35. Anterior Leaflet: Commisural Repair Techniques M.De Bonis AATS Mitral Conclave Hilton New York, Avenue of the Americas, New York, NY, USA May 2-3, 2013

36. The Valve Is Still Leaking After Repair: One Stitch More To Fix It? M. De Bonis AATS Mitral Conclave Hilton New York, Avenue of the Americas, New York, NY, USA May 2-3, 2013

37. Veno-arterial ECMO for fulminant myocarditis in adult patients: A multi- institutional experience. R.Lorusso, M. De Bonis, F. Pappalardo et al. Euro-Elso 2013, Karolinska University Hospital, Stockholm, Sweden, 8-11 May, 2013

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38. Cardiac support with IABP during VV ECMO for ARDS: A new strategy for right ventricular failure. M. Pieri, M. De Bonis, F. Pappalardo et al. Euro-Elso 2013, Karolinska University Hospital, Stockholm, Sweden, 8-11 May, 2013

39. La destination therapy: esperienza iniziale al San Raffaele. M. De Bonis. Congresso: “Attività di coordinamento e gestione domicilaiare di pazienti portatori di dispositivi di assistenza ventricolare (VAD) per il trattamento dell’insufficienza cardiaca terminale: il VAD coordinator”. Ospedale Universitario San Raffaele, Milano, 14 Giugno 2013

40. Terapia medica e chirurgica delle endocarditi infettive: qual è il timing ottimale della chirurgia. M. De Bonis XII Congresso Nazionale della Società Italiana di Malattie Infettive e tropicali (SIMIT) Centro Congressi San Raffaele, Milano, 27-30 Ottobre 2013

41. Functional mitral regurgitation: patient specific surgical solutions M. De Bonis Kosuyolu Valve Repair Workshop 2013 Kosuyolu Hospital, Istanbul, Turkey, 1-2 November 2013

42. Tricuspid repair technique: patient specific surgical solutions. M. De Bonis Kosuyolu Valve Repair Workshop 2013 Kosuyolu Hospital, Istanbul, Turkey, 1-2 November 2013

43. L’omissione dell’annuloplastica in corso di riparazione chirurgica: outcome a distanza. M. De Bonis 5° Meeting Italiano Tecniche Riparative Avanzate Live Ecocardiografia Centro Congressi San Raffaele, Milano, Italy, 14-15 November 2013

44. Results of the edge-to-edge repair: implications for use of the Mitraclip. M. De Bonis Ask the expert session: controversies in mitral valve repair for degenerative disease. American Heart Association Scientific Session 2013, Novembre 19, 2013. Dallas, Texas, USA (Control# 4771)

45. Tricuspid valve repair: standard procedure or customized dress? M. De Bonis Italian Society of Cardiac Surgery Tutorial Course SICCH Clinical - Valve surgery: an update on current trends and future perspectives Rome, Ergife Palace Hotel, November 29th – 30th, 2013

46. Valvular heart disease in heart failure: vicious twins.

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The surgeon’s perspective. M. De Bonis Heart Failure Congress 2014 Athens, Greece, 17-20 May 2014

47. Mitral regurgitation: a multidisciplinary challenge. Surgery. M. De Bonis Heart Failure Congress 2014 Athens, Greece, 17-20 May 2014

48. Mitraclip: the missing ring. M. De Bonis European Society of Cardiology Congress 2014 Barcelona, Spain, 30 August-3 September 2014

49. An interim analysis of the NOSTRUM randomized trial. M. De Bonis European Society of Cardiology Congress 2014 Barcelona, Spain, 30 August-3 September 2014

50. Long-term results of the MitraClip therapy: what can we foresee at more than 10 years from the surgical experience. M. De Bonis 28th European Association for Cardiothoracic Surgery Annual Meeting Milan, Italy, 14 October 2014.

51. Strategy of cannulation: minimally invasive valve surgery M. De Bonis 28th European Association for Cardiothoracic Surgery Annual Meeting Milan, Italy, 15 October 2014.

52. Five of my favourite techniques to repair mitral insufficiency M. De Bonis EACTS Postgraduate Course on Adult Cardiovascular Surgery Turkish Society of Cardiovascular Surgery – 13th Congress Antalya, Turkey, October 31st, 2014

53. Should we do edge-to-edge repair? M. De Bonis EACTS Postgraduate Course on Adult Cardiovascular Surgery Turkish Society of Cardiovascular Surgery – 13th Congress Antalya, Turkey, October 31st, 2014

54. Strategy of cannulation: Minimally invasive valve surgery M. De Bonis Day/Date: Wednesday, October 15, 2014 Session: Advanced techniques Part II: Cannulation and extraction techniques – putting in and taking it out. 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014.

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55. Long-term results of the MitraClip therapy: what can we forsee at more than 10 years from the surgical experience M. De Bonis Day/Date: Wednesday, October 15, 2014 Focus Session: Trans-catheter heart valve therapy a look to the future 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014.

56. Should less than severe tricuspid regurgitation be addressed during left sided surgery? M. De Bonis The Heart Valve Society, 1st Annual Meeting Grimaldi Forum Monte Carlo, Monaco, May 7-9 2015

57. A severe secondary MR with poor LV function, AF and no option for revascularisation. M. De Bonis Session: Mitral valve surgery 2015 European Society of Cardiology Congress 29 August - 2 September 2015, London - United Kingdom

58. An endocarditis with neurologic complication M. De Bonis Session: Complex endocarditis 2015 European Society of Cardiology Congress 29 August - 2 September 2015, London - United Kingdom

59. Severe secondary tricuspid regurgitation after the mitral valve surgery: what do the Guidelines say? M. De Bonis Session: Mitral and tricuspid disease: keeping up with the Guidelines 2015 European Society of Cardiology Congress 29 August - 2 September 2015, London - United Kingdom

60. Should less than severe tricuspid regurgitation be treated during mitral valve repair? M. De Bonis Abstract Session: “Revisiting the tricuspid valve” 29th EACTS Annual Meeting, Amsterdam, The Netherlands, 3-7 October 2015.

61. Surgery for functional mitral valve regurgitation. M. De Bonis 68th Japanese Association for Thoracic Surgery, October 16-20, 2015, Kobe, Japan.

62. Should we treat less than severe secondary tricuspid regurgitation? M. De Bonis 68th Japanese Association for Thoracic Surgery, October 16-20, 2015, Kobe, Japan.

63. Anatomical pitfalls in heart valve surgery M. De Bonis Postgraduate Course keynote lecture

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68th Japanese Association for Thoracic Surgery, October 16-20, 2015, Kobe, Japan.

64. MitraClip – the surgeon perspective M.De Bonis The 4th Heart Valve Summit of the Israel Heart Society 18th Novemebr 2015,Tel Aviv, Israel

65. How to deal with preoperative anemia in the patients needing CABG. M.De Bonis The junior teach the senior and viceversa. Myocardial revascularization: new trials, new guidelines, new trends. 27-28 Novemebr 2015,Hotel Massimo D’Azeglio,Rome

66. Lettura magistrale: la terapia chirurgica nello scompenso cardiaco M.De Bonis Focus on scompenso cardiac e fibrillazione atriale 28th Novemebr 2015 Aula Magna P.O. Melfi, Potenza

67. Is there a need for trans-catheter tricuspid devices? M.De Bonis 9th International Live Case Meeting Latest Techniques in Cardiac Surgery Leipzig Heart Center, Lepzig, Germany, 3-5 December 2015

68. Treatment of end-stage heart failure M. De Bonis Milan Cardiology, February 18-20, 2016 San Raffaele Congress Center, Milan, Italy

69. Is there yet a place for surgical repair in secondary mitral regurgitation? M. De Bonis EuroValve Hotel Bloom, Bruxelles, Belgium March 10-11 2016

70. Percutaneous bicuspidization of the tricuspid valve M.B. Ancona, F. Giannini, D. Regazzoli, A. Mangieri, B. Bellini, L. Azzalini, F. Monaco, M. De Bonis, M. Montorfano, A. Latib, O. Alfieri, A. Colombo. Presentation C 87 47° Congresso Nazionale ANMCO Rimini, Italy, 2-4 June 2016

71. First in man prolonged pressure-controlled intermittent coronary sinus occlusion to treat refractory left ventricular dysfunction and ischemia M.B. Ancona, F. Pappalardo, D. Regazzoli, A. Mangieri, F. Giannini, M. Montorfano, M. De Bonis, O. Alfieri, A. Colombo, A. Latib. Presentation C 379 47° Congresso Nazionale ANMCO Rimini, Italy, 2-4 June 2016

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72. Early percutaneous Impella implantation in post-infarct ventricular septal rupture: early hemodynamic stabilization in order to delay surgery and reduce surgical risk. M.B. Ancona, F. Giannini, F. Figini, D. Regazzoli, A. Mangieri, R. Jabbour, L. Azzalini, M.Montorfano, A. Latib, F. Monaco, M. De Bonis, A. Colombo. Presentation C 417 47° Congresso Nazionale ANMCO Rimini, Italy, 2-4 June 2016

73. LVAD implantation in redo cases: how to make it simple. M. De Bonis EuroELSO 2016 1-4 june 2016, SECC Glasgow, United Kingdom

74. Case based heart-team for MR - An old patient with severe degenerative MR and heavily calified annulus (echo+procedure video) M. De Bonis Session: Heart-team based management of mitral regurgitation: when the cardiologists meet the surgeons European Society of Cardiology Congress 27-31 August 2016, Rome, Italy

75. Timing of surgery in late TR following MV surgery: an unsolved issue. M. De Bonis Session: Heart-team based management of tricuspid regurgitation: when the cardiologists meet the surgeons European Society of Cardiology Congress 27-31 August 2016, Rome, Italy

76. Late tricuspid regurgitation after left sided valve surgery – Clinical case. M. De Bonis Session: Open issues in Valvular heart disease European Society of Cardiology Congress 27-31 August 2016, Rome, Italy

77. Treatment options in intermediate-high risk patients with aortic stenosis and renal dysfunction: the European multicenter propensity match study comparing TAVR versus conventional AVR surgery. Poster area (P842) – Valvular Disease/Pulmonary C. Muneretto, O. Alfieri, G. Bisleri, M. De Bonis, R. Di Bartolomeo, C. Savini, G. Folesani, L. Di Bacco, J.P. Maureira, F. Laborde, M. Tespili, A. Repossini, T. Folliguet. European Society of Cardiology Congress 27-31 August 2016, Rome, Italy

78. Current limitations of percutaneous edge to edge repair. M. De Bonis 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain

79. A case of endocarditis with neurological complications. M. De Bonis

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30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain

80. Late tricuspid regurgitation after previous mitral valve Why are they referred too late for surgery? M. De Bonis 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain

81. Commissural prolapse M. De Bonis Mitral Surgery - EACTS Academy 7-9 November 2016, Leiden, The Netherlands

82. Interventional and Surgical edge-to-edge M. De Bonis Mitral Surgery - EACTS Academy 7-9 November 2016, Leiden, The Netherlands

83. Insufficienza mitralica e tricuspidalica M. De Bonis Master di I Livello 2016 in Ecocardiografia valvolare Piacenza, 22 November 2016

84. Emergency vascular access for ECMO M. De Bonis 7th International Congress Aortic and Peripheral Surgery – How to do it San Raffaele Hospital, Milan, Italy, 15-17 December 2016

85. Chirurgia riparativa dell’insufficienza valvolare aortica senza ricostruzione della radice: risultati a medio e lungo termine di un’esperienza monocentrica M. De Bonis, T. Nisi, E. Lapenna, A. Giacomini, A. Castiglioni, B. Del Forno, G. La Canna, O. Alfieri 77° Congresso Nazionale della Società Italiana di Cardiologia 16-19 December 2016, Rome, Italy

86. How to minimize the surgical risk in patients with severe late tricuspid regurgitation after previous left sided valve surgery: our standard surgical technique M. De Bonis, B. Del Forno, E. Lapenna, N. Buzzatti, T. Nisi, G. La Canna, M. Calabrese, O. Alfieri. 77° Congresso Nazionale della Società Italiana di Cardiologia 16-19 December 2016, Rome, Italy

87. MitraClip's current limitations M. De Bonis Heart Valve Society Scientific Meeting Grimaldi Forum, Monaco 2-4 March 2017

88. Annuloplasty and leaflet repair: A gold standard in surgery

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M. De Bonis Heart Valve Society Scientific Meeting Grimaldi Forum, Monaco 2-4 March 2017

89. Insufficienza tricuspidalica ad insorgenza tardiva dopo intervento di sostituzione valvolare mitralica. M. De Bonis Conoscere e curare il cuore 2017 25-27 March 2017, Firenze

90. Il trattamento chirurgico dell’insufficienza tricuspidalica: tecniche, risultati e limiti. M. De Bonis IX Congresso nazionale ecocardiochirurgia 2017 27-29 March, 2017

91. Chirurgia tradizionale vs Chirurgia mini-invasiva e Mitraclip M. De Bonis II congresso nazionale collegio federativo di cardiologia Italian council of cardiology practice 31 March-1 April 2017, Palermo

92. How to minimize the surgical risk in patients with severe late tricuspid regurgitation after previous left sided valve surgery: our standard surgical technique M. De Bonis, B. Del Forno, E. Lapenna, O. Alfieri 48° Congresso Nazionale Associazione Nazionale Medici Cardiologi Ospedalieri 11-13 May 2017, Rimini

93. Long–term results of minimally invasive edge–to–edge repair for severe mitral valve regurgitation due to bileaflet prolapse in Barlow’s disease. E. Lapenna, M. De Bonis, B. Del Forno, A. Giacomini, S. Di Sanzo, G. La Canna, O. Alfieri 48° Congresso Nazionale Associazione Nazionale Medici Cardiologi Ospedalieri 11-13 May 2017, Rimini

94. Left ventricular assist device therapy for patients at high operative risk due to prior cardiac surgery: an useful and safe strategy. B. Del Forno, M. De Bonis, E. Lapenna, A. Giacomini, F. Pappalardo, O. Alfieri 48° Congresso Nazionale Associazione Nazionale Medici Cardiologi Ospedalieri 11-13 May 2017, Rimini

95. Risultati a medio termine dell’ablazione chirurgica della fibrillazione atriale concomitante a miectomia settale in pazienti affetti da cardiomiopatia ipertrofica ostruttiva. E. Lapenna, M. De Bonis, A. Pozzoli, T. Nisi, B. Del Forno, G.. La Canna, O. Alfieri.

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48° Congresso Nazionale Associazione Nazionale Medici Cardiologi Ospedalieri 11-13 May 2017, Rimini

96. Surgical approaches in functional tricuspid regurgitation: indications, techniques and outcomes, and the case for earlier intervention. M. De Bonis Euro PCR May 16th – 19th 2017, Paris

97. Mitral valve repair in a patient with severe ventricular dysfunction M. De Bonis European Society of Cardiology Congress 2017 26-28 August 2017, Barcelona, Spain

98. ESC Guidelines 2017: Tricuspid valve disease M. De Bonis European Society of Cardiology Congress 2017 26-28 August 2017, Barcelona, Spain

99. Management of secondary mitral regurgitation, what do the guidelines recommend? M. De Bonis 31st EACTS Annual Meeting 7-11 October 2017, Vienna

100. Tricuspid Valve: when to repair, when to Replace? M. De Bonis 2nd Annual Excellence in Cardiac Care 10-11 November 2017, Dubai

101. LVAD as destination therapy in refractory congestive HF M. De Bonis 2nd Annual Excellence in Cardiac Care 10-11 November 2017, Dubai

102. MitraClip has many limitations. M. De Bonis M.I.T.R.A.L.E. 7° Meeting on Advanced Echocardiography Repairing Techniques November 23rd/24th, 2017, Milan

103. Mitral valve: old and new technologies: the viewpoint of a cardiac surgeon. M. De Bonis SICCH 50th anniversary: the excellence of Italy in cardiovascular diseases. 24-25 November 2017, Rome

104. Ischemic mitral insufficiency: what about new ESC guidelines? Surgical treatment: repair or replacement? M. De Bonis

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28es Journées Européennes de la Société Française de Cardiologie 17th-20th January 2018, Paris

105. Which valve for surgical TVR? M. De Bonis Mitral Valve Meeting 2018, 26-28 February 2018, Zurich, Switzerland

Chairmanships at National and International Congresses

1. Mitral Valve Surgery Chairmen: M. De Bonis, M. Kolowca 23rd European Association for Cardiothoracic Surgery Meeting, Vienna, Austria, 19th October 2009.

2. L’insufficienza cardiaca che avanza Discussant: M. De Bonis Convention Centri Scompenso della Lombardia Antico Borgo la Muratella, Bergamo, 6-7th May, 2010

3. Mitral valve repair. Film session Chairmen: M. De Bonis, G Seeburger 24th EACTS Annual Meeting, Geneva, Switzerland, 13 September 2010.

4. Mitral and Tricuspid Valves I Chairmen: M. Antunes, M. De Bonis 25th European Association for Cardiothoracic Surgery Meeting, Lisbon, Portugal, 1-5 October 2011.

5. Controversies in valvular heart surgery. Chairmen: V. Falk, M. De Bonis European Society of Cardiology Congress 2012, Munich, Germany, 28 August 2012

6. Surgery for valvular heart disease: predictors of outcome. Chairmen: D. Adams, M. De Bonis European Society of Cardiology Congress 2012, Munich, Germany, 28 August 2012

7. Unanswered questions in right ventricular failure Moderators: M. De Bonis, L. A. Menicanti 26th European Association for Cardiothoracic Surgery Meeting, Barcelona, Spain, 27-30 October 2012.

8. Mitral valve surgery. Chairmen: Zanobini M, De Bonis M XXVI National Congress of the Italian Society for Cardiac Surgery, Rome, Ergife Palace Hotel, 10-13 November 2012

9. End-stage heart failure. Long-term/permanent support. Chairmen: De Bonis M, Pepper J.

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Focus session 7 October 2013 27th EACTS Annual Meeting, Vienna, Austria, 4-9 October 2013.

10. Valve surgery: from prediction to outcome Chairmen: Grabenwoeger M, De Bonis M. European Society of Cardiology Congress 2014, Barcelona, Spain, 30 August-3 September 2014

11. Transcatheter heart valve therapy: a look to the future Chairmen: M. De Bonis, A. Vahanian Day/Date: Tuesday, October 14, 2014 Session Time: 14:15 - 15:45 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014.

12. Cannulation and extraction techniques - Putting it in and taking it out Moderators: C. Starck, M. De Bonis Day/Date: Wednesday, October 15, 2014 Session Time: 10:30 - 12:00 28th EACTS Annual Meeting, Milan, Italy, 11-15 October 2014.

13. Endocarditis and infections. Chairmen: De Bonis M, G. Nappi, L. Botta XXVII National Congress of the Italian Society for Cardiac Surgery, Rome, Ergife Palace Hotel, 28-30 November 2014

14. From pure revascularisation to concomitant mitral valve repair: controversies and challenges ESC and the European Association for Cardio-Thoracic Surgery Chairpersons: R. Yadav (London, GB), M. De Bonis (Milano, IT) Session Date: 30 Aug 2015 Session Time: 08:30 - 10:00 2015 European Society of Cardiology Congress 29 August - 2 September 2015, London - United Kingdom

15. Mitral Valve Repair wet lab Chairperson: M. De Bonis, Milan; S. Livesey, Southampton; R. Sadaba, Gorraiz 29th EACTS Annual Meeting, Amsterdam, The Netherlands, 3-7 October 2015.

16. Challenges in the management of secondary mitral regurgitation Chairperson: M. De Bonis, G. Habib EuroValve Hotel Bloom, Bruxelles, Belgium March 10-11 2016

17. Current trends in endocarditis Chairperson: P. Tornos, M. De Bonis European Society of Cardiology Congress 27-31 August 2016, Rome, Italy

18. Valve repair and assist devices Chairperson: JF. Obadia, M. De Bonis European Society of Cardiology Congress

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27-31 August 2016, Rome, Italy

19. Mitral Valve Repair wet lab Chairperson: M. De Bonis, Milan; R. Klautz 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain

20. Minimally invasive cardiac surgery simulator M. De Bonis, P. Sardari Nia Mitral Surgery - EACTS Academy 7-9 November 2016, Leiden, The Netherlands

21. Translational coronary bypass surgery Joint session with ESC working group on cardiovascular surgery Chairperson: M. Czerny, M. De Bonis XXVIII Italian Society of Cardiac (SICCH) National Congress Rome, Ergife Palace Hotel, November 25th – 27th, 2016

22. Translational science 2 Chairperson: M. De Bonis, G. Di Giammarco XXVIII Italian Society of Cardiac (SICCH) National Congress Rome, Ergife Palace Hotel, November 25th – 27th, 2016

23. Interactive session: what is your diagnosis? Chairperson: Pilar Tornos, Michele De Bonis EuroValve Barcelona, Spain 26-27 January 2017

24. MitraClip: Lights and Shadows Chairperson: M. De Bonis, N. Buzzatti Heart Valve Society Scientific Meeting Grimaldi Forum, Monaco 2-4 March 2017

25. Scompenso cardiaco refrattario Chairperson: P. Agostoni, M. De Bonis VAD-EMECUM Lombardia 2017 Como, giovedì 30 Marzo 2017

26. Post- cardiotomy ECMO in adults: facts, challenges, and new strategies Chairperson: W. Bhure, M. De Bonis 6th International EuroELSO Congress, 4-7 May 2017, Maastricht, the Netherlands

27. Percutaneous edge-to-edge repair for degenerative mitral regurgitation Wednesday 17 May 2017 Live Demonstration Panelist: M. De Bonis, S. Kar , F. Maisano, D. Walters, O. Wendler Euro PCR May 16th – 19th 2017, Paris

28. Decision making in mitral surgery: trying to fill the gaps in evidence!

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Chaiperson: V. Falk, M. De Bonis 31st EACTS Annual Meeting 7-11 October 2017, Vienna

29. Introduction to mitral valve repair & Wetlab Room -2.16 Advanced Techniques Chairperson: M. De Bonis, S. Livesey, R. Klautz 31st EACTS Annual Meeting 7-11 October 2017, Vienna

Faculty Member of the following Congresses

1. 56th European Society for Cardio-Vascular Surgery International Congress Venice, Italy, Lido Casino Palace, May 17-20, 2007

2. 4th International Congress Aortic Surgery and Anesthesia San Raffaele Hospital, Milan, Italy, 17 December 2010

3. 5th International Congress Aortic surgery and anesthesia “How to do it” San Raffaele Hospital, Milan, Italy, 13-15 December 2012

4. AATS Mitral Conclave Hilton New York, Avenue of the Americas, New York, NY, USA May 2-3, 2013

5. 27th European Association for Cardiothoracic Surgery Annual Meeting Vienna, Austria, 4-9 October 2013.

6. Kosuyolu Valve Repair Workshop 2013 Kosuyolu Hospital, Istanbul, Turkey, 1-2 November 2013

7. 5° Meeting Italiano Tecniche Riparative Avanzate Live Ecocardiografia Centro Congressi San Raffaele, Milano, Italy, 14-15 November 2013

8. Heart Failure Congress 2014 Athens, Greece, 17-20 May 2014

9. European Society of Cardiology Congress 2014 Barcelona, Spain, 30 August-3 September 2014

10. 28th European Association for Cardiothoracic Surgery Annual Meeting Milan, Italy, 11-15 October 2014.

11. Turkish Society of Cardiovascular Surgery – 13th Congress Antalya, Turkey, 30 October – 2 November 2014

12. 6th International Congress

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Aortic surgery and anesthesia “How to do it” San Raffaele Hospital, Milan, Italy, 12-14 December 2014

13. 2015 European Society of Cardiology Congress 29 August - 2 September 2015, London - United Kingdom

14. 29th EACTS Annual Meeting 3-7 October 2015, Amsterdam, The Netherlands.

15. M.I.T.R.A.L.E. 6th Meeting on advanced live echocardiography repairing techniques October 8-9 2015, San Raffaele Congress Center, Milan, Italy

16. 68th Japanese Association for Thoracic Surgery October 16-20, 2015, Kobe, Japan.

17. 9th International Live Case Meeting Latest Techniques in Cardiac Surgery Leipzig Heart Center, Lepzig, Germany, 3-5 December 2015

18. Milan Cardiology San Raffaele Congress Center, Milan, Italy February 18-20, 2016

19. EuroValve Hotel Bloom, Bruxelles, Belgium March 10-11 2016

20. EuroELSO 2016 1-4 june 2016, SECC Glasgow, United Kingdom

21. European Society of Cardiology Congress 27-31 August 2016, Rome, Italy

22. Reconstruction of the Aortic Valve and Root: A practical approach September 14th-16th, 2016 University Hospital of Saarland Homburg/Saar, Germany

23. 30th EACTS Annual Meeting 1-5 October 2016, Barcelona, Spain

24. Mitral Surgery EACTS Academy 7-9 November 2016, Leiden, The Netherlands

25. XXVIII Italian Society of Cardiac (SICCH) National Congress Rome, Ergife Palace Hotel, November 25th – 27th, 2016

26.7th International Congress Aortic and Peripheral Surgery – How to do it San Raffaele Hospital, Milan, Italy, 15-17 December 2016

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27. EuroValve Barcelona, Spain 26-27 January 2017

28. Heart Valve Society Scientific Meeting Grimaldi Forum, Monaco 2-4 March 2017

29. II congresso nazionale collegio federativo di cardiologia Italian council of cardiology practice 31 March-1 April 2017, Palermo

30. 6th International EuroELSO Congress, 4-7 May 2017, Maastricht, the Netherlands

31. Euro PCR May 16th – 19th 2017, Paris

32. European Society of Cardiology Congress 2017 26-28 August 2017, Barcelona, Spain

33. 31st EACTS Annual Meeting 7-11 October 2017, Vienna

34. M.I.T.R.A.L.E. 7° Meeting on Advanced Echocardiography Repairing Techniques November 23rd/24th, 2017, Milan

Reviewer for the following international journals:

American Journal of Cardiology Annals of thoracic surgery British medical journal on line Circulation European heart journal Expert reviews in cardiology European Journal of Cardio-thoracic surgery European Medical Journal Heart Heart, vessels and Lungs Interactive Journal of Thoracic and Cardiovascular Surgery Internationational Journal of Cardiology Journal of thoracic and cardiovascular surgery Journal of heart valve disease Nature reviewes in cardiology The Lancet

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Milan, 16th February, 2018 NAME AND SURNAME (SIGNATURE)

Michele De Bonis