naplex drugs table

105
NAPLEX Review Brand Generic Class Other Combivir zidovudine 300mg/ lamivudine 150mg NRTI combo See individual drugs Trizivir zidovudine 300mg/ lamivudine 150mg/ abacavir 300mg NRTI combo See individual drugs Truvada tenofovir 300mg/ emtricitabi ne 200mg NRTI combo See individual drugs Epzicom abacavir 600mg/ lamivudine 300mg NRTI combo See individual drugs Agenerase amprenavir (APV) PI Rash, Gi intolerance, oral paresthesias Reyataz atazanavir (ATV) PI take with food, hyperbilirubi nemia,

Upload: starobin

Post on 27-Dec-2015

270 views

Category:

Documents


8 download

TRANSCRIPT

Page 1: NAPLEX Drugs Table

NAPLEX Review

Brand Generic Class Other

Combivir

zidovudine 300mg/ lamivudine 150mg

NRTI comboSee individual drugs

Trizivir

zidovudine 300mg/ lamivudine 150mg/ abacavir 300mg

NRTI comboSee individual drugs

Truvada

tenofovir 300mg/ emtricitabine 200mg

NRTI comboSee individual drugs

Epzicom

abacavir 600mg/ lamivudine 300mg

NRTI comboSee individual drugs

Ageneraseamprenavir (APV)

PIRash, Gi intolerance, oral paresthesias

Reyatazatazanavir (ATV)

PI

take with food, hyperbilirubinemia, prolonged PR interval

Lexivafosamprenavir (f-APV)

PISkin Rash, with or without food

Crixivan indinavir (IDV) PI take on empty

Page 2: NAPLEX Drugs Table

stomach, nephrolithiasis, hyperbilirubinemia

Kaletralopinavir/ ritonavir (LPV/r)

PITake with food, hypertriglyceridemia, GI intolerance

Viracept nelfinavir (NFV) PITake with food, severe diarrhea

Norvir ritonavir (RTV) PI

hepatotoxicity, GI intolerance, pancreatitis, keep refrigerated, good at room temp for 1 month

Invirasesaquinavir (hard gel) (HGC)

PI GI intolerance

Fortovasesaquinavir (soft gel) (SGC)

PI

GI intolerance, keep refridgerated, room temperature for 3 months

Rescriptordelavirdine (DLV)

NNRTIRash, increased LFTs, HA

Sustiva efavirenz (EFV) NNRTI

intial DOC, CNS sx, rash, inc. LFTs, teratogenic, take on empty stomach

Viramunenevirapine(NVP)

NNRTI

Rash, symptomatic hepatitis, w/out regard to meals

Page 3: NAPLEX Drugs Table

Ziagen abacavir, ABC NRTIhypersensitivity, EtOH inc levels by 41%

Videx didanosine, ddI NRTI

Pancreatitis, periph. neuropathy, inc SE with d4T use, take on empty stomach

Emtrivaemtricitabine, FTC

NRTI

Min. toxicity, hyperpigmentation, do not use with 3TC

Epivirlamivudine, 3TC

NRTIMin. toxicity, do not use with FTC

Zerit stavudine, d4T NRTI

Periph. neuropathy, lipoatrophy, pancreatitis, dyslipdemia, no use w/ AZT, inc SE w/ddI

Viread tenofovir (TDF) NRTINephrotoxicity, osteopenia

Hividzalcitabine, ddC

NRTI

Periph. neuropathy, stomatitis, pancreatitis

Retrovir zidovudine, AZT, ZDV

NRTI Bone-marrow suppression, useful in reducing Mother to Child transmission, no

Page 4: NAPLEX Drugs Table

use with d4T

Keflex, Keftab cephalexin 1st Gen. Ceph (blank)

Duricef, Ultracef cefadroxil 1st Gen. Ceph (blank)

Velosef cephradine 1st Gen. Ceph (blank)

Cefadyl cephapirin 1st Gen. Ceph (blank)

Ancef, Kefzol Cefazolin 1st Gen. Ceph (blank)

Ceclor cefaclor 2nd Gen. Ceph (blank)

Mefoxin cefoxitin 2nd Gen. Cephgood antianaerobic activity

Ceftin, Kefurox, Zinacef

cefuroxime 2nd Gen. Ceph for UTIs

Monocid cefonicid 2nd Gen. Ceph (blank)

Zefazone cefmetazole 2nd Gen. Cephdisulfiram-like rx with alcohol

Cefotan cefotetan 2nd Gen. Ceph

good antianaerobic activity, disulfiram-like rxn with alcohol

Cefzil cefprozil 2nd Gen. Ceph (blank)

Lorabid loracarbef 2nd Gen. Ceph (blank)

Omnicef cefdinir 3rd Gen. Ceph (blank)

Spectracef cefditoren 3rd Gen. Ceph (blank)

Suprax cefixime 3rd Gen. Ceph (blank)

Page 5: NAPLEX Drugs Table

Vantin cefpodoxime 3rd Gen. Ceph (blank)

Cefobid cefoperazone 3rd Gen. Ceph

good antipseudomonal activity, disulfiram-like rxn with alcohol

Claforan cefotaxime 3rd Gen. Cephgood Strept. pneumoniae cov.

Cefizox ceftizoxime 3rd Gen. Ceph (blank)

Rocephin ceftriaxone 3rd Gen. Cephgood S. pneumoniae coverage

Fortaz, Tazidime, Tazicef

ceftazidime 3rd Gen. Cephgood antipseudomonal action

Cedax ceftibuten 3rd Gen. Ceph (blank)

Maxipime cefepime 4th Gen. Cephgood antipseudomonal activity

Nydrazide isoniazid antitubercularVit B6 deficiency, hepatotoxicity

Rifadin, Rimactane

rifampin antitubercular

enzyme inducer, hepatotoxic, orange discoloration of bodily fluids

(blank) pyrazinamide antitubercular

intial combo for TB, hepatotoxicity, hyperuricemia

Page 6: NAPLEX Drugs Table

Myambutol ethambutol antitubercular (blank)

(blank) streptomycin antitubercularaminoglycoside, ototoxicity/nepthrotoxicity

Lariam mefloquine hcl antimalarialsneuropsychiatric AE

Malaroneatovaquone/proguanil

antimalarialsfor chloroquine-resistant strains,

Aralen chloroquine antimalarials

monitor for ocular or auditory changes, may cause neuropathy, worsen psoriasis sx

Plaquenilhydroxychloroquine

antimalarials

also used for tx of SLE and Rheumatoid arthritis, phototoxicity

Naturetinbendroflumethiazide

Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

Aquatag, Exna benzthiazide Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

Diruil Chlorothiazide Thiazide Diuretic increased

Page 7: NAPLEX Drugs Table

cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

Hygroton, Hylidone

Chlorthalidone Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

HydroDIURIL, Microzide

HCTZ Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

Saluron, Diucardin

Hydroflumethiazide

Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

(blank)Methyclothiazide

Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

Renese Polythiazide Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

Page 8: NAPLEX Drugs Table

Metahydrin, Naqua

Trichlormethiazide

Thiazide Diuretic

increased cholesterol and glucose, decrease K, Na, and Mg, increased uric acid and Ca

Mykrox MetalazoneThiazide Like diuretic

Less or no hypercholesteolemia than thiazides

Zaroxolyn Metolazone Thiazide LikeLess or no hypercholesterolemia than thiazides

Lozol Indapamide Thiazide LikeLess or no hypercholesterolemia than thiazides

Midamor Amiloride K-sparing Hyperkalemia

Dyrenium Triamterene K-sparingAvoid with hx of kidney stones or hepatic disease

Hylorel GuanadrelPostganglionic Adrenergic Neuron Blocker

Postural Hypotension, diarrhea

IsmelinGuanethidine monosulfate

Postganglionic Adrenergic Neuron Blocker

Postural Hypotension, diarrhea

Serpasil reserpine Postganglionic Adrenergic Neuron Blocker

Nasal congestion, sedation, depression, activation of peptic ulcer, memory impairment, wt gain, sleep

Page 9: NAPLEX Drugs Table

disturbances

Catapres clonidine HClCentrally active alpha 2 agonists

sedation, dry mouth, bradycardia, withdrawal HTN, impotence

Wytensinguanabenz acetate

Centrally active alpha 2 agonists

sedation, dry mouth, bradycardia, withdrawal HTN, impotence

Tenex guanfacine HClCentrally active alpha 2 agonists

sedation, dry mouth, bradycardia, withdrawal HTN, impotence

Aldomet MethyldopaCentrally Active alpha 2 agonists

sedation, dry mouth, bradycardia, withdrawal HTN, impotence

Carduradoxazosin mesylate

Peripherally acting alpha 1 blockers

syncope, diarrhea, wt gain, edema, dry mouth, priapism, no effects on glucose or cholesterol

Minipress Prazosin hcl Peripherally acting alpha 1 blockers

syncope, diarrhea, wt gain, edema, dry mouth, priapism, no effects on glucose or

Page 10: NAPLEX Drugs Table

cholesterol

Hytrin Terazosin hclPeripherally acting alpha 1 blockers

syncope, diarrhea, wt gain, edema, dry mouth, priapism, no effects on glucose or cholesterol

Kerlone Betaxolol BBmay mask hypoglycemia

Cartrol Carteolol BB ISA

Levatolpenbutolol sulfate

BB ISA

Blocadren timolol maleate BB (blank)

Normodyne, Trandate

labetalol BB/alpha blocker (blank)

Apresoline Hydralazine hcl Direct VasodilatorHA, fluid retention, tachycardia

Loniten minoxidil Direct vasodilator Hirsutism

DynaCirc, CR isradipineCCB dihydropyridine

edema of the ankle, flushing, HA, gingival hyperplasia

Caredene SR nicardipineCCB dihydropyridine

edema of the ankle, flushing, HA, gingival hyperplasia

Sular nisoldipine CCB dihydropyridine

edema of the ankle, flushing,

Page 11: NAPLEX Drugs Table

HA, gingival hyperplasia

Univasc moexipril ACEI

cough, angiodema, hyperkalemia, loss of taste

Aceon perindopril ACEI

cough, angiodema, hyperkalemia, loss of taste

Mavik trandolapril ACEI

cough, angiodema, hyperkalemia, loss of taste

Teveten eprosartan ARBangioedema, hyperkalemia

Cozaar losartan ARBangioedema, hyperkalemia

Micardis telmisartan ARBangioedema, hyperkalemia

Intropin dopamine Inotrope

increases HR, contractility, myocardial O2 demand, use for systemic hypotension or cardigenic shock

Dobutrex dobutamine Inotrope

increases HR, contractility, myocardial O2 demand, not useful to increase BP

Page 12: NAPLEX Drugs Table

Primacor milrinone Inotrope

arrhythmias, hypotension, HA, alt to dopamine/dobutamine, may be useful if on BB

Nipride nitroprussideArterial and venous dilator

Hypotension, HA, tachycardia, cyanide and thiocyanate toxicity, myocardial ischemia

Natrecor nesiritidearterial and venous dilator

hypotension, HA w/diuretics, is a B-type natriuretic peptide

Quinaglute Dura-Tabs, Duraquin, Quinalan, Quinatime

Quinidine gluconate

Antiarrhythmic Class Ia

QTc prolongation, torsades de pointes, diarrhea

Quinidex, Cin-Quin, Quinora

Quinidine sulfate

Antiarrhythmic Class Ia

QTc prolongation, torsades de pointes, diarrhea

CardioquinQuinidine polygalacturate

Antiarrhythmic Class Ia

QTc prolongation, torsades de pointes, diarrhea

Procanbid, Pronestyl

procainamide Antiarrhythmic Class Ia

Lupus-like syndrome, QTc prolongation, torsades de pointes, hypotension,

Page 13: NAPLEX Drugs Table

dizziness, blurred vision, GI distress

Norpace, CR disopyramideAntiarrhythmic Class Ia

Anticholinergic side effects, decreased cardiac contractility, HF, QTc prolongation, torsades de pointes, hypoglycemia

Ethmozine moricizineAntiarrhythmic Class Ia

dizziness, nausea, paresthesias, proarrhythmia

Lidocaine LidocaineAntiarrhythmic Class Ib

CNS toxicity: paresthesias, dizziness, confusion, N/V, seizures

Tonocard tocainideAntiarrhythmic Class Ib

GI distress, CNS: tremor, dizziness, confusion, seizures; pulmonary fibrosis/pneumonitis, agranulocytosis

Mexitil mexiletine Antiarrhythmic Class Ib

GI distress, tremor, dizziness, confusion, nystagmus, diplopia, hypotension, AV block, sinus bradycardia,

Page 14: NAPLEX Drugs Table

vertigo

Tambocor flecainideAntiarrhythmic Class Ic

proarrhythmia, prolongedPR interval and QRS complex, HF, blurred vision, dizziness

Rythmol propafenoneAntiarrhythmic Class Ic

metallic/bitter taste, HF, liver injury, agranulocytosis, CNS, GI distress

Lopressor metoprololAntiarrhythmic Class II

(blank)

Inderal, LA propranololAntiarrhythmic Class II

(blank)

Breviblock esmololAntiarrhythmic Class II

(blank)

Bretylol bretyliumAntiarrhythmic Class III

Adrenergic blocking effects, inital HTN followed by hypotension, hyperthermia, GI distress

Cordarone amiodarone Antiarrhythmic Class III

corneal microdeposits, photophobia, increased liver enzymes, photosensitivity, blue-gray skin discoloration,

Page 15: NAPLEX Drugs Table

pulmonary fibrosis, hyper- and hypothyroidism, polyneuropathy

Betapace, AF sotalolAntiarrhythmic Class III

bradycardia, fatigue, dyspnea, bronchospasm, HF, QTc prolongation, torsades de pointes

Corvert ibutilideAntiarrhythmic Class III

QTc prolongation, torsades de pointes

Tikosyn dofetilideAntiarrhythmic Class III

QTc prolongation, torsades de pointes

Calan, Isoptin, Covera-HS, Verelan

verapamilAntiarrhythmic Class IV

Bradycardia, hypotension, HF, constipation

Cardizem, Cartia, Dilacor, Diltia, Tiazac

DiltiazemAntiarrhythmic Class IV

Hypotension, bradycardia, HF

Adenocard adenosinemisc antiarrhythmic

(blank)

Lanoxin, Lanoxicaps

Digoxinmisc antiarrhythmic

(blank)

Atropine atropinemisc antiarrhythmic

(blank)

Viagra sildenafil (blank) (blank)

Page 16: NAPLEX Drugs Table

Levitra vardenafil (blank) (blank)

Cialis tadalafil (blank) (blank)

Reopro abciximabGlycoprotein IIb/IIIa Receptor Inhibitor

antibody, bleeding, thrombocytopenia, allergic rxn from repeated exposure

Integrillin eptifibatideGlycoprotein IIb/IIIa Receptor Inhibitor

bleeding, thrombocytopenia

Aggrastat tirofibanGlycoprotein IIb/IIIa Receptor Inhibitor

bleeding, thrombocytopenia

Streptase, SK streptokinase Thrombolytic

bleeding, intracranial hemorrhage, stroke, epistaxis

Alteplase, tPAtissue plasminogen activator

Thrombolytic

bleeding, intracranial hemorrhage, stroke, epistaxis

Retevase, rPA reteplase Thrombolytic

bleeding, intracranial hemorrhage, stroke, epistaxis

TNKase, TNK tenecteplase Thrombolytic

bleeding, intracranial hemorrhage, stroke, epistaxis

Lescol fluvastatin Statin myopathy, myalgia,

Page 17: NAPLEX Drugs Table

rhabdomyolysis, elevated liver enzymes, flu-like symptoms, HA

Altoprev lovastatin XR Statin

myopathy, myalgia, rhabdomyolysis, elevated liver enzymes, flu-like symptoms, HA

Questrancholestryramine

Resin, BAS

GI distress, palatability problems, constipation in elderly

Colestid colestipol Resin, BAS

GI distress, palatability problems, constipation in elderly

WelChol colesevelam Resin, BAS

GI distress, palatability problems, constipation in elderly

NiacorNicotinic acid, immediate release

Nicotinic acid

flushing, hyperglycemia risk, hyperuricemia

Slo-NiacinNicotinic acid, sustained release

Nicotinic acid

flushing, hyperglycemia risk, hyperuricemia

Page 18: NAPLEX Drugs Table

NiaspanNicotinic acid, extended release

Nicotinic acid

flushing, hyperglycemia risk, hyperuricemia

AdvicorNiaspan + Lovasatin

Combo Cholesterol product

myopathy, myalgia, rhabdomyolysis, elevated liver enzymes, flu-like symptoms, HA, flushing, hyperglycemia risk, hyperuricemia

Dymelor acetohexamide1st gen sulfonylurea

GI, hematologic, disulfiram-like rxn, SIADH, wt gain, hypoglycemia

Diabinese chlorpropamide1st gen sulfonylurea

GI, hematologic, disulfiram-like rxn, SIADH, wt gain, hypoglycemia

Tolinase tolazamide1st gen sulfonylurea

GI, hematologic, disulfiram-like rxn, wt gain, hypoglycemia

Orinase tolbutamide1st gen sulfonylurea

GI, hematologic, disulfiram-like rxn, wt gain, hypoglycemia, SIADH

Glyset miglitolAlpha glucosidase inhibitor

GI, decreased serum iron

Page 19: NAPLEX Drugs Table

Prandin repaglinidemeglitinides/nonsulfonylurea secretagogues

hypoglycemia, wt gain, URI, back pain, flu sx

Starlix nateglinidemeglitinides/nonsulfonylurea secretagogues

hypoglycemia, wt gain, URI, back pain, flu sx

Glucovanceglyburide and metformin

combo diabetic medication

(blank)

Cytomel, Triostat

liothyronine T3 Thyroid Tx

tachycardia, arrhythmia, angina, Mi, HA, insomnia, irritability, D/V, cramps, wt loss, excessive sweating, heat intolerance, fever, hair loss

ThyrolarLiotrix T4 + T3 (4:1)

(blank)

tachycardia, arrhythmia, angina, Mi, HA, insomnia, irritability, D/V, cramps, wt loss, excessive sweating, heat intolerance, fever, hair loss

PTU propylthiouracil Antithyroid

Fever, HA, rash, jaundice, agranulocytosis, leukopenia, DOC in pregnacy

Tapazole methimazole Antithyroid fever, HA, rash,

Page 20: NAPLEX Drugs Table

juandice, hepatitis, agranulocytosis, leukopenia, bleeding

Lugol's solution

5% iodine and 10% K iodide, 6.3 mg iodine/drop

Antithyroid

fever, HA, rash, juandice, hepatitis, agranulocytosis, leukopenia, bleeding

SSKI

Saturated solution of potassium iodide 1 g/ml, 38 mg iodine/drop

Antithyroid

fever, HA, rash, juandice, hepatitis, agranulocytosis, leukopenia, bleeding

Cytadrenaminoglutethimide

Tx of cushing's syndrome

rash, weakness, hypotension, loss of appetite

Lysodren mitotaneTx of cushing's syndrome

nausea, vomiting, diarrhea, tiredness

Metopirone metyrapoineTx of cushing's syndrome

N/V, dizziness, sedation

Pitressin vasopressin (blank)

angina, MI, vasoconstriction, hyponatremia, gangrene,

Stimate (DDAVP)

desmopressin (blank) abd pain, HA, flushing, nasal irritaiton, vulvar pain, nosebleed,

Page 21: NAPLEX Drugs Table

rhinitis

Cortone cortisone corticosteroid (blank)

Cortef, Hydrocortone, Solu-Cortef

hydrocortisone corticosteroid (blank)

Deltasone, Liquid Pred

prednisone corticosteroid (blank)

Prelone, Pediapred, Delta-Cortef

prednisolone corticosteroid (blank)

Medrol, Solu-Medrol, Depo-Medrol, A-Methapred

methylprednisolone

corticosteroid (blank)

Aristocort, Kenacort, Kenalog

triamcinolone corticosteroid (blank)

Decadron, dexameth, Dexone, Hexadrol

dexamethasone

corticosteroid (blank)

Celestonebethamethasone

corticosteroid (blank)

Florinef fludrocortisone corticosteroid (blank)

Cortrosyn cosyntropindiagnosis of adrenal insufficiency

(blank)

Acthar (ACTH) corticotropindiagnosis of adrenal insufficiency

(blank)

Page 22: NAPLEX Drugs Table

Testoderm, Androderm

testosterone transdermal system

Androgen

jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

AndroGel 1%, Testim

testosterone Androgen

jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

Depo-Testosterone

testosterone cypionate (in oil)

Androgen

jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

Android, Testred

methyltestosterone

Androgen jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and

Page 23: NAPLEX Drugs Table

libiod, certain effects in women and men

Halotestinfluoxymesterone

Androgen

jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

Anadrol-50 oxymetholone Anabolic Steroid

jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

Winstrol stanozolol Anabolic Steroid

jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

Oxandrin oxandrolone Androgen jaundice, hepatitis, edema, high abuse

Page 24: NAPLEX Drugs Table

potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

Deca-Durabolinnandrolone deconoate

Androgen

jaundice, hepatitis, edema, high abuse potential, hypercholesterolemia, increased aggression and libiod, certain effects in women and men

Premarin

conjugated equine estrogens (CEE)

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Estradiol, Estrace, Gynodiol

Micronized estradiol

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Estropipate, Ortho-Est, Ogen

Estrone sulfate Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast

Page 25: NAPLEX Drugs Table

cancer, breast tenderness, heavy bleeding, headache, nausea

Estratab, Menest

Esterified estrogens

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Estraderm, Alora, Climara, Esclim, Vivelle, Vivelle-Dot

Estradiol transdermal system

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Estrace vaginal cream

0.1 mg estradiol/g

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Ogen vaginal cream

1.5 mg estropipate/g

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache,

Page 26: NAPLEX Drugs Table

nausea

Premarin vaginal cream

0.625 mg conjugated estrogen/g

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Estring vaginal ring

2 mg estradiol ring releases 7.5 ug/24 h

Hormone replacement therapy

ring remains in vaginal for 3 months, increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Vagifem vaginal tablet

25 ug estradiol/tablet

Hormone replacement therapy

increased risks fro VTE, stroke, CHD, and breast cancer, breast tenderness, heavy bleeding, headache, nausea

Activella

1 mg estradiol, 0.5 mg norethindrone acetate

Combination estrogen-progestin

Progestin: depression, HA, irritability

femhrt 2.5 or 5 ug ethinyl estradiol, 0.5 or

Combination estrogen-progestin

Progestin: depression, HA, irritability

Page 27: NAPLEX Drugs Table

1 mg norethindrone acetate

Prempro

conjugated estrogen and medroxyprogesterone

Combination estrogen-progestin

Progestin: depression, HA, irritability

Premphase

conjugated estrogen, 5 mg medroxyprogesterone

Combination estrogen-progestin

2 weeks of estrogen alone, 2 weeks of combination; Progestin: depression, HA, irritability

Climara Pro (transdermal .)

0.045 mg estradiol; 0.15 mg levonorgestrel

Combination estrogen-progestin

Progestin: depression, HA, irritability

Combi.

0.05 mg estradiol; 0.14 or 0.25 mg norethindrone acetate

Combination estrogen-progestin

Progestin: depression, HA, irritability

Estartest H.S., Syntest H.S.

0.625 mg esterified estrogens, 1.25 mg methyltestosterone

Combination estrogen-androgen product

androgen: fluid retention, undesirable changes in lipid profile, virilization (lower HDL)

Estratest, Syntest D.S.

0.625 mg esterified estrogens, 2.5 mg methyltestoster

Combination estrogen-androgen product

androgen: fluid retention, undesirable changes in lipid profile, virilization

Page 28: NAPLEX Drugs Table

one (lower HDL)

Citracal (+ Vit D)

calcium citrate (+ 200 IU)

Calcium supplement

24% calcium content, take without regard to meals, GI upset, HA, hypophosphatemia, hypercalcemia

Caltrate 600, Titralac, Tums, Viactive Chews, Mylanta lozenges

Calcium carbonate

Calcium supplement

40% calcium content, take with food to facilitate absorption, GI upset, HA, hypophosphatemia, hypercalcemia

Caltrate 600 + D, Calcilyte + vitamin D, Oscal + vitamin D

Calcium carbonate + Vit D

Calcium supplement

GI upset, HA, hypophosphatemia, hypercalcemia

Posture, Posture-D

Calcium phosphate tribasic (125 IU vit D)

Calcium supplement

39% calcium content, GI upset, HA, hypophosphatemia, hypercalcemia

Fosamax Alendronate bisphosphonate

abdominal pain, dyspepsia, N/C/D/F, HA must be taken with a full glass of water (8oz) 30 minutes prior to first meal of the day must remain upright for at least 30 mins following

Page 29: NAPLEX Drugs Table

Actonel risedronate bisphosphonate

abdominal pain, dyspepsia, N/C/D/F, HA must be taken with a full glass of water (8oz) 30 minutes prior to first meal of the day must remain upright for at least 30 mins following

Evista raloxifeneselective estrogen receptor modulator

hot flashes, chest pain, N/V/D, arthralgia, myalgia, insomnia, sweating

Miacalcin calcitoninanti osteoporosis agent

facial flushing and hand flushing, N/V/D, salty taste, rhinitis, nasal dryness

Forteo teriparatide

Parathyroid hormone, PTH, anti osteoporosis agent

pain, arthralgia, paresthesias, N/D, metallic taste, injection pain

Epogen, Procrit Epoetin alfaerythropoietic growth factors

HTN, RBC aplasia, seizures, polycythemia, thrombocytosis

AranespDarbepoetin alfa

erythropoietic growth factors

HTN, RBC aplasia, seizures, polycythemia, thrombocytosis

Page 30: NAPLEX Drugs Table

Fer-In-Sol, Feosol, Slow FE

Ferrous sulfate iron supplementsstomach cramping, N/V/C, dark stools

Femiron, Vitron-C

Ferrous fumarate

iron supplementsstomach cramping, N/V/C, dark stools

FergonFerrous gluconate

iron supplementsstomach cramping, N/V/C, dark stools

Hytinic, Niferecpolysaccharide iron

iron supplementstomach cramping, N/V/C, dark stools

Proferrin-ESheme iron polypeptide

iron supplementstomach cramping, N/V/C, dark stools

Ferrlecitsodium ferric gluconate

iron supplement hypersensitivity

Venofer Iron sucrose iron supplement hypersensitivity

InFeD, Dexferrum

Iron dextran iron supplement hypersensitivity

Desferal deferoxaminetreatment of iron overload

(blank)

Drisdol, Calciferol

ErgocalciferolVitamin D precursor

hypercalcemia, hyperphosphatemia, adynamic bone disease

Calcijex, Rocaltrol

Calcitriol Active Vit D

hypercalcemia, hyperphosphatemia, adynamic bone disease

Page 31: NAPLEX Drugs Table

Zemplar Paricalcitol Vit D analog

hypercalcemia, hyperphosphatemia, adynamic bone disease

Hectorol doxercalciferol Vit D analog

hypercalcemia, hyperphosphatemia, adynamic bone disease

Nephrocaps, Nephrovite, Nephrovite Rx, Renavite, Biotin Forte

Vit B complex, Vit C, folic acid

Water soluble Vit supplements

dependent on vitamin

Nephrovite Rx + Iron, NephrPlex Rx

Vit B complex, Vit C, folic acid, and iron

water soluble vit supplement

dependent on vitamin

Allbee with CVitamin B complex

water soluble vit supplement

dependne on vitamin

Toradol Ketorolac Analgesic Max use 5 days

Versed midazolam Benzoacute and short term <24-73 h

Diprivan profofol Sedativeuse when rapid awakening needed

Pavulon pancuronium NMBgeneral NMB of choice, tachycardia

Norcuron vecuronium NMB

use in hemodynamic instability, renal dysfunction, cardiac disease

Page 32: NAPLEX Drugs Table

Nimbex cisatracurium NMBuse in renal and hepatic dysfunction

Xigris drotrecogin alfa Sepsis agentrecombinant human activated protein C

KayexalateNa polystyrene sulfonate

Anti hyperkalemia agent

(blank)

Mustargenmechlorethamine

chemotherapy alklyalting agent

myleosuprresion, alopeica, N/V, amenorrhea and azoospermia, seizures

Cytoxan, Neosar

cyclophosphamide

chemotherapy alklyalting agent

myleosuprresion, alopeica, N/V, amenorrhea and azoospermia, seizures

Ifex Ifosfamidechemotherapy alklyalting agent

myleosuprresion, alopeica, N/V, amenorrhea and azoospermia, seizures

BICNU carmustinechemotherapy alklyalting agent

myleosuprresion, alopeica, N/V, amenorrhea and azoospermia, seizures

Zanosar streptozocinchemotherapy alklyalting agent

myleosuprresion, alopeica, N/V, amenorrhea and azoospermia, seizures

Page 33: NAPLEX Drugs Table

Alimta pemitrexedchemotherapy antimetabolite

severe diarrhea, n/v, faitigue, alopeica

Rheumatrex methotrexatechemotherapy antimetabolite

severe diarrhea, n/v, faitigue, alopeica, renal toxicity, mucositis

Adrucilfluorouracil, 5-FU

chemotherapy antimetabolite

Hand-foot syndrome, stomatitis, mucositis, renal toxicity

Xeloda capecitabinechemotherapy antimetabolite

Hand-food syndrome, stomatitis

Purinethol mercaptopurinechemotherapy antimetabolite

(blank)

Gemzar gemcitabinechemotherapy antimetabolite

rash and fever, flu-like sx, hemolytic uremic syndrome

Fludara fludarabinechemotherapy antimetabolite

severe diarrhea, gi damage, n/v, myleosupression, alopecia, neurotoxicity, opportunistic infections

Adriamycin, Doxil

doxorubicin antitumor antibiotics

severe n/v, alopecial, stomatitis, cardiac toxicty, limit on cumulative

Page 34: NAPLEX Drugs Table

lifetime dosing

Cerubidine, Daunoxome

daunorubicin antitumor antibiotic

severe n/v, alopecial, stomatitis, cardiac toxicty, limit on cumulative lifetime dosing

idamycin Idarubicin antitumor antibiotic

severe n/v, alopecial, stomatitis, cardiac toxicty, limit on cumulative lifetime dosing

Cosmegen dactinomycinanti tumor antibiotic

severe n/v, alopecial, stomatitis, cardiac toxicty, limit on cumulative lifetime dosing, renal toxicity, leukopenia, increased pigmentation of previously radiated skin

Megacemegestrol acetate

ProgestinFor breast and endometrial cancer

Nolvadex tamoxifen antiestrogen breast cancer

Faslodex fulvestrant antiestrogen breast cancer

Fareston toremifene antiestrogen breast cancer

Arimidex anastrozolearomatase inhibitor

breast cancer

Page 35: NAPLEX Drugs Table

Femara letrozolearomatase inhibitor

breast cancer

Casodex bicalutamide antiandrogen prostate cancer

Lupron, Eligard leuprolide LHRH agonistprostate, breast cancer

Plenaxis abarelix GNRH agonist

prostate cancer, black box warning for hypotension and syncope

Taxotere doxetaxelPlant alkaloids chemotherapy

myelosoupression, mucositis, N/V, alopecia, edema

Taxol, Abraxane paclitaxelPlant alkaloids chemotherapy

hypotension/hypersensitivty upon admin

VePesid etoposidePlant alkaloids chemotherapy

diarrhea, HA, secondary malignancies

Vumon teniposidePlant alkaloids chemotherapy

diarrhea, HA, secondary malignancies

Camptosar irinotecanPlant alkaloids chemotherapy

diarrhea, HA, secondary malignancies

Hycamtin topotecanPlant alkaloids chemotherapy

diarrhea, HA, secondary malignancies

Oncovin vincristinePlant alkaloids chemotherapy

neurotoxicity, SIADH

Velban vinblastine Plant alkaloids SIADH

Page 36: NAPLEX Drugs Table

chemotherapy

Navelbine vinorelbinePlant alkaloids chemotherapy

SIADH

Proleukin aldesleukin immune therapy (blank)

Intron Ainterferon-alfa 2b

immune therapy (blank)

Rituxan rituximabmonoclonal antibody

(blank)

Herceptin trastuxumabmonoclonal antibody

(blank)

Mylotarg gemtuzumabmonoclonal antibody

(blank)

Campath alemtuzumabmonoclonal antibody

(blank)

Avastin bevacizumabmonoclonal antibody

(blank)

Erbitux cetuximabmonoclonal antibody

(blank)

OntakDenileukin diftitox

monoclonal antibody

(blank)

Zevalinibritumomab fluxetan

monoclonal antibody

(blank)

Bexxar tositumomabmonoclonal antibody

(blank)

Platinol-AQ cisplatin chemotherapy platinum

nephrotoxicity, peripheral neurotoxicity, myelosuppression, ototoxicity, N/V,

Page 37: NAPLEX Drugs Table

hydration therapy and premdication are needed

Paraplatin carboplatinchemotherapy platinum

nephrotoxicity, peripheral neurotoxicity, myelosuppression, ototoxicity, N/V

Eloxatin oxaliplatinchemotherapy platinum

nephrotoxicity, peripheral neurotoxicity, myelosuppression, ototoxicity, N/V

Elspar asparaginasechemotherapy enzyme

myelosuppression, h yperuricemia, hyperglycemia, renal problems

Gleevacimatinib mesylate

tyrosine kinase inhibitor

phila chromosome, hepatotoxicty, fluid retention, neutropenia, n/V

Tarceva erlotinibtyrosine kinase inhibitor

Her-1, EGFR, rash, diarrhea, anorexia, stomatitis, intersitital lung disease, for NSCLC

Iressa gefitinibtyrosine kinase inhibitor

EGRF, 3rd line agent for NSCLC, diarrhea, rash, acne, dry skin

Page 38: NAPLEX Drugs Table

Anzemet dolasetron 5-HT3 rec antag

HA, constipation, blurred vision, elevated liver enzymes

Kytril granisetron 5-HT3 rec antag

HA, constipation, blurred vision, elevated liver enzymes

Zofran ondansetron 5-HT3 rec antag

HA, constipation, blurred vision, elevated liver enzymes

Aloxi palonosetron 5-HT3 rec antag

HA, constipation, blurred vision, elevated liver enzymes

Marinol dronabinol cannabinoids

n/v with cancer, drowsiness, euphoria, dry mouth

Emend aprepitantneurokinin-1 antagonist

n/v with cancer, somnolence, fatigue, diarrhea

Sandimmune, Neoral

cyclosporineimmunosuppressant

seizure, hallucinations, gingival hyperplasia, hypertension, hepato and nephrotoxicity, DM

Prograf tacrolimus immunosuppressant

seizure, hallucinations,

Page 39: NAPLEX Drugs Table

alopeica, HTN, DM, anemia

Rapamune sirolimusimmunosuppressant

anorexia, oral ulcers, diarrhea, rash, acne, hyperlipidemia, HTN

Imuran azathioprineimmunosuppressant

retinopathy, n/v/d/a, rash, skin cancer, penias

Cellceptmycophenolate mofetil

immunosuppressant

n/v/d/abd pain, hematologic

Arava leflunomideimmunosuppressant

ha, neuralgia, alopecia, n/v/d/a, DM, hyperlipidemia, hyperthyroidism

Furoxone furazolidone antibacterial

use if biaxin and flagyl resistance is suspected in PUD tx regimens

Azulfidine sulasalazine aminosalicylate

n/v/a, hypersensitivity rxn, altered spermatogenesis

asacol, pentasa, rowasa

mesalamine aminosalicylate better tolerated

colazal balsalazide aminosalicylate abd pain

Zelnorm tergaserod5 HT4 serotonin receptor antagonist

for IBS, diarrhea, nausea, HA, abd pain

Page 40: NAPLEX Drugs Table

Enbrel etanercepet DMARD (blank)

Remicade Infliximab DMARD (blank)

Humira adalimumab DMARD (blank)

Benemid probenecid uricosuric agent

for gout, uric acid stones, take with food to avoid abd discomfort

Anturane sulfinpyrazone uricosuric agentgi discomfort and uric stone formation

Ergomar, ergostat, Gynergen

ErgotamineMigraine tx Abortive

N/V, weakness in legs, myalgia, numbness and tingling, angina like pain, tachy or bradycardia

Bellergal

Ergotamine 0.3mg/pentobarbital 20mg/bellafoline 0.1 mg

Migraine tx Abortive

N/V, weakness in legs, myalgia, numbness and tingling, angina like pain, tachy or bradycardia

Bellamine, Bellamine S, Bellaphen S, Bellergal-S, Duragal S

ergotamine 0.6 mg/pentobarbital 40 mg/ belladonna 0.2 mg

Migraine tx Abortive

N/V, weakness in legs, myalgia, numbness and tingling, angina like pain, tachy or bradycardia

Midrin Isometheptene 65 mg/ dichloralphenazone 100 mg/APAP 325

Migraine tx Abortive

(blank)

Page 41: NAPLEX Drugs Table

mg

Axert almotriptanAbortive migraine tx

tingling and paresthesias, sensations of warmth in head, neck, chest, limbs, flushing, neck pain or stiffness

Imitrex sumatriptainAbortive migraine tx

tingling and paresthesias, sensations of warmth in head, neck, chest, limbs, flushing, neck pain or stiffness

Relpax eletriptanAbortive migraine tx

tingling and paresthesias, sensations of warmth in head, neck, chest, limbs, flushing, neck pain or stiffness

Frova frovatriptanabortive migraine tx

tingling and paresthesias, sensations of warmth in head, neck, chest, limbs, flushing, neck pain or stiffness

Maxalt rizatriptan abortive migraine tx

tingling and paresthesias,

Page 42: NAPLEX Drugs Table

sensations of warmth in head, neck, chest, limbs, flushing, neck pain or stiffness

Zomig zolmitriptanabortive migraine tx

tingling and paresthesias, sensations of warmth in head, neck, chest, limbs, flushing, neck pain or stiffness

Amerge naratriptanabortive migraine tx

tingling and paresthesias, sensations of warmth in head, neck, chest, limbs, flushing, neck pain or stiffness

Tegretol, Carbatrol

carbamazepine anticonvulsant

rash, N/V, FDA BBW: hepatotoxicity and aplastic anemia

Barbital, Luminal, Solfoton

phenobarbital anticonvulsant

hyperactivity in children, lower memory and concentration abilities, folate deficiency, SJS, hepatic failure

Dilantin phenytoin anticonvulsant peripheral neuropathy,

Page 43: NAPLEX Drugs Table

hydantoin facies, acne, hirsuitism, GINGIVAL HYPERPLASIA, osteomalcia, SJS, teratogenic

Depakene, Depakote, Depacon

Divalproex sodium, sodium valproate (Depacon)

anticonvulsant

wt gain, alopecia, tremor, FDA BBW: hepatotoxicity and hemorrhagic pancreatitis, and teratogenic

Felbatol felbamatenewer anticonvulsant

rarely used, sig wt loss, FDA BBW: hepatotoxicity, aplastic anemia

Neurontin Gabapentinnewer anticonvulsant

severe life-threatening side effects NONE

Lamictal Lamotriginenewer anticonvulsant

FDA BBW: skin rash

Topamax topiramatenewer anticonvulsant

kidney stones, word finding difficulties, loss of appetite, FDA BBW: Oligohidrosis (may not sweat)

Gabitril tiagabinenewer anticonvulsant

Severe life threatening side effects NONE

Zonegran zonisamide newer kidney stones, wt

Page 44: NAPLEX Drugs Table

anticonvulsantloss, psychosis, Bold warning for oligohidrosis

Keppra Levetiracetamnewer anticonvulsant

dizziness, faitgue, sedation

Thorazine chlorpromazineTypical antipsychotic

more sedating, more orthostasis, more weight gain and Anti-ACh sx

Mellaril thioridazineTypical antipsychotic

more sedating, more orthostasis, more weight gain and Anti-ACh sx, BBW: QT prolongation

Prolixin fluphenazineTypical antipsychotic

more EPS sx

Haldol haloperidolTypical antipsychotic

more EPS sx

Trilafon perphenazineTypical antipsychotic

not commonly used

Navane thiothixeneTypical antipsychotic

not commonly used

Stelazine trifluoperazineTypical antipsychotic

not commonly used

Loxitane loxapineTypical antipsychotic

not commonly used

Clozaril clozapine Atypical antipsychotic

sedation, wt gain, hypersalivation, seizure risk >600 mg/d, no EPS or

Page 45: NAPLEX Drugs Table

TD, Weekly CBC! Refractory schizophrenia only

Risperdal, Risperdal Consta

risperidoneAtypical antipsychotic

dose related EPS, +\- wt gain and sedation, prolactin elevation, orthostasis, do not mix with teas or colas

Zyprexa, Zyprexa Zydis

OlanzapineAtypical antipsychotic

sedation, orthostasis

Seroquel QuetiapineAtypical antipsychotic

low EPS risk

Geodon ZiprasidoneAtypical antipsychotic

+\- sedation and wt gain, QT prolongation warning

Abilify aripiprazoleAtypical antipsychotic

possible insomnia, +\- wt gain, QD dosing

Eskalith CR, Lithobid

lithium Mood stabilizer

tremor, polydipsia/polyuria, N/D, wt gain, hypothyroidism, mental dulling

Elavil amitriptyline TCA, tertiary Orthostatic hypotension, tachycardia, sedation, anticholingergic effects, prolonged

Page 46: NAPLEX Drugs Table

QT interval, wt gain, sexual dysfunction

Pamelor, Aventyl

nortriptyline TCA, secondary

Orthostatic hypotension, tachycardia, sedation, anticholingergic effects, prolonged QT interval, wt gain, sexual dysfunction

Tofranil Imipramine TCA, tertiary

Orthostatic hypotension, tachycardia, sedation, anticholingergic effects, prolonged QT interval, wt gain, sexual dysfunction

Sinequan doxepin TCA, tertiary

Orthostatic hypotension, tachycardia, sedation, anticholingergic effects, prolonged QT interval, wt gain, sexual dysfunction

Anafranil clomipramine TCA, tertiary Orthostatic hypotension, tachycardia, sedation, anticholingergic effects, prolonged

Page 47: NAPLEX Drugs Table

QT interval, wt gain, sexual dysfunction

Norpramin Desipramine TCA, secondary

Orthostatic hypotension, tachycardia, sedation, anticholingergic effects, prolonged QT interval, wt gain, sexual dysfunction

Nardil phenelzine MAOI

Orthostatic hypotension, wt gain, sexual dysfunction, anticholinergic effects, and hypertensive crisis

Parnatetranylcypromine

MAOI

Orthostatic hypotension, wt gain, sexual dysfunction, anticholinergic effects, and hypertensive crisis

Clexa citalopram SSRI

geriatric pts, fewer DI, GI complaints, insomnia, HA, fatigue, sexual dysfunction, nervousness

Lexapro escitalopram SSRI GI complaints,

Page 48: NAPLEX Drugs Table

insomnia, HA, fatigue, sexual dysfunction, nervousness

Luvox fluvoxamine SSRI

For OCD DI, GI complaints, insomnia, HA, fatigue, sexual dysfunction, nervousness

Paxil, Paxil CR paroxetine SSRI

GI complaints, insomnia, HA, fatigue, sexual dysfunction, nervousness

Prozac, Sarafem

fluoxetine SSRI

Longer t1/2 no tapering, GI complaints, insomnia, HA, fatigue, sexual dysfunction, nervousness

Zoloft Sertraline SSRI

geriatric pts, fewer DI, GI complaints, insomnia, HA, fatigue, sexual dysfunction, nervousness

Effexor, Effexor XR

VenlafaxineSNRI (serotonin/norepinephrine)

GI upset,anxiety, insominia, HA, elevation in BP,

Cymbalta Duloxetine SNRI Gi upset, dry mouth, dizziness, decreased

Page 49: NAPLEX Drugs Table

appetite, elevation in BP, urinary hesitation

Wellbutrin, SR, XL, Zyban

buproprionNDRI (NE/DA reuptake inhibitor)

GI upset, insomnia, anxiety, HA and psychosis, less sexual dysfunction, decreases seizure threshold

Desyrel trazodone SSRI

extremly sedating, orthostatic hypotension, priapism

Serzone Nefazodone SNRI

Gi upset, sedation, dry mouth, constipation, lightheadedness, minimal sexual dysfunction and/or orthostatic hypotension, BBW: hepatotoxicity

Remeron, Remeron Soltab

mirtazapine Antidepressant

sedation, increased appetite, wt gain, constipation, elevation in LFTs, increase in TGs, small risk of agranulocytosis or neutropenia

Page 50: NAPLEX Drugs Table

Xanax, Niravam alprazolam BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

Libriumchlordiazepoxide

BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

Tranxene clorazepate BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

ProSom estazolam BzD sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced

Page 51: NAPLEX Drugs Table

psychomotor and cognitive dysfunction

Dalmane flurazepam BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

Paxipam halazepam BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

Serax oxazepam BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

Centrax prazepam BZD sedation, dizziness, confusion, blurred

Page 52: NAPLEX Drugs Table

vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

Doral quazepam BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

Halcion triazolam BZD

sedation, dizziness, confusion, blurred vision, diplopia, syncope, residual daytime sedation, reduced psychomotor and cognitive dysfunction

BuSpar buspirone Anti anxiety

Gi upset, HA, nervousness, less sedating than BZDs, little to no psychomotor or cognitive impairment, no abuse potential

Symbyax olanzapine/ antidepressant BBW increased

Page 53: NAPLEX Drugs Table

fluoxetinesuicide thinking and behavior

Mentax, Lotrimin Ultra

butenafine topical antifungal (blank)

Accutane, Amnesteem, Claravis, Sotret

isotretinoin anti acne

for severe, nodulocystic, draining acne, iPLEDGE program, take with food, TERATOGENIC, Cheilitis, Dry mouth, Dry skin, Pruritus, Dry nose, Dry eyes, muscular soreness or stiffness

Rogaine Minoxidil Anti Alopecia

scalp dermatitis, hypertrichosis on areas other than scalp

PropeciaFinasteride 1mg

anti alopecia

gynecomastia, hypersensitvity, decreased libido, ED, ejaculatory dysfunction, CI in women

Aquacare, Carmol

ureakeratin-softening agent

(blank)

LactiCare, Lowila Cake

Lactic Acidkeratin-softening agent

(blank)

Alphosyl, allantoin keratin-softening (blank)

Page 54: NAPLEX Drugs Table

Psorex, Tegrin agent

Burow's solutionaluminum acetate

astringent (blank)

Witch hazelhamamelis water

astringent (blank)

Synalarfluocinolone acetate

topical corticosteroid medium potency

striae, thinning of epidermis, systemic effects

Cordran flurandrenolidetopical corticosteroid medium potency

striae, thinning of epidermis, systemic effects

Locoidhydrocortisone butyrate

topical corticosteroid medium potency

striae, thinning of epidermis, systemic effects

Westcorthydrocortisone valerate

topical corticosteroid medium potency

striae, thinning of epidermis, systemic effects

Valisone, Dermabet

Betamethasone valerate

topical corticosteroid medium potency

striae, thinning of epidermis, systemic effects

Topicortdesoximetasone

topical corticosteroid Very high potency

striae, thinning of epidermis, systemic effects

Maxiflor, Psorcon

diflorasone diacetate

topical corticosteroid very high potency

striae, thinning of epidermis, systemic effects

Lidex fluocinonidetopical corticosteroid very high potency

striae, thinning of epidermis, systemic effects

Halog halcinonide topical striae, thinning of

Page 55: NAPLEX Drugs Table

corticosteroid very high potency

epidermis, systemic effects

Diprosone, Maxivate, Diprolene AF

betamethasone dipropionate

topical corticosteroid ultra high potency

striae, thinning of epidermis, systemic effects

Temovateclobetasol propionate

topical corticosteroid ultra high potency

striae, thinning of epidermis, systemic effects

UltravateHalobetasol propionate

topical corticosteroid ultra high potency

striae, thinning of epidermis, systemic effects

Protopic tacrolimus immunomodulator

stinging, burning, pruritus, rare flu-like sx, use sunscreen

Elidel pimecrolimus immunomodulator

stinging, burning, pruritus, rare flu-like sx, use sunscreen

Rid, A-200, Barc, End-Lice, Pronto, R&C shampoo, Triple X

Synergized pyrethrins

anti pediculosis

Must repeat tx, irritation, erythema, itching, do not use if ragweed allergy

Nix, Elimite, Acticin

Permethrin anti pediculosisOne time tx, CI in chrysanthemum allergy

Ginkgo biloba ginkgo biloba herbal

enhance memory and concentration, d/c prior to surgery

St. John's wort Hypericum herbal depression/

Page 56: NAPLEX Drugs Table

perforatumanxiety use, photosensitvity

Asian ginseng asian ginseng herbal

fatigue/enhance concentration, SE: HTN, euphoria, insomnia, D/C prior to surgery

Garlicallium sativum L.

herballower cholesterol, D/C prior to surgery

Echinacea purpurea

echinacea purpurea

herbalUse cold/RTI, CI if allergy to daisy family

Saw palmetto serenoa repens herbalBPH, SE: HTN, UT sx

kava-kava kava-kava herbal

anxiety/stress use, SE similar to alcohol, kava dermopathy, liver failure

Ma huang ephedra herbal withdrew in 2004

S-adenosylmethionine

SAMenonbotanical natural products

depression/osteoarthritis use, SE: gas, V/N/D

Melatonin melatoninnonbotanical natural products

sleep disorders/jet lag use, SE: infertility, HA

Dehydroepiandrosterone

DHEA nonbotanical natural products

depression, general anti-aging effects, osteoporosis, antidiabetogenic,

Page 57: NAPLEX Drugs Table

SE ily skin, acne, hirsuitism, abnormal menses

Glucosamine glucosaminenonbotanical natural products

osteoarthritis, SE: nausea, heartburn

Unisom doxylaminenonprescription insomnia product

(blank)

Nytol, sominexdiphenhydramine

nonprescription insomnia product

(blank)

QVARbeclomethasone HFA

inhaled corticosteroid

cough, dysphonia, oral thrush

Pulmicort budesonideinhaled corticosteroid

cough, dysphonia, oral thrush

Aerobid flunisolideinhaled corticosteroid

cough, dysphonia, oral thrush

Flovent fluticasoneinhaled corticosteroid

cough, dysphonia, oral thrush

Azmacort triamcinoloneinhaled corticosteroid

cough, dysphonia, oral thrush

Foradil formoterollong acting inhaled B2 agonist

tachycardia, muscle tremor, hypokalemia, prolongation of QTc interval in overdose

Serevent salmeterollong acting inhaled B2 agonist

tachycardia, muscle tremor, hypokalemia, prolongation of QTc interval in overdose

Page 58: NAPLEX Drugs Table

Maxair pirbuterolshort acting inhaled b2 agonist

tachycardia, tremor, hypokalemia, increased lactic acid, HA, hyperglycemia

Amikin amikacin aminoglycoside

nephrotoxicity, ototoxicity, peak 15-30 ug/ml, trough <5 ug/ml

Garamycin gentamicin aminoglycoside

nephrotoxicity, ototoxicity, peak 4-10 ug/ml, trough <2 ug/ml

kanamycin kanamycin aminoglycosidenephrotoxicity, ototoxicity

neomycin neomycin aminoglycosidenephrotoxicity, ototoxicity

netilmicin netilmicin aminoglycosidenephrotoxicity, ototoxicity

streptomycin streptomycin aminoglycosidenephrotoxicity, ototoxicity

tobramycin, Tobi

tobramycin aminoglycoside

nephrotoxicity and ototoxicity, trough <2 ug/ml, peak 4-10 ug/ml

Pfizerpen Penicillin G natural penicillin allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions,

Page 59: NAPLEX Drugs Table

interstital neprhritis

Wycillinpenicillin G procaine

natural penicillin

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Bicillin LAPenicillin G benzathine

natural penicillin

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Pen-Vee K, Veetids

Penicillin V natural penicillin

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Prostaphilin, Bactocil

oxacillin penicillinase-resistant penicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions,

Page 60: NAPLEX Drugs Table

interstital neprhritis, increased transaminases

Nafcil, Unipen nafcillinpenicillinase-resistant penicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis, increased transaminases

Cloxapen cloxacillinpenicillinase-resistant penicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Dynapen, Dycil dicloxacillinpenicillinase-resistant penicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Omnipen, Principen

ampicillin aminopenicillins allergic rx, n/v with po use, seizures with high

Page 61: NAPLEX Drugs Table

doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Amoxil, Trimox amoxicillin aminopenicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Spectrobid bacampicillin aminopenicillin

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Geopen carbenicillin carboxypenicillin

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Ticar ticarcillin carboxypenicillin allergic rx, n/v with po use, seizures with high

Page 62: NAPLEX Drugs Table

doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Azlin azlocillin ureidopenicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Mezlin mezlocillin ureidopenicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Pipracil piperacillin ureidopenicillins

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Augmentin amoxicillin/clavulanic acid

penicillin plus Beta lactamase inhibitor

allergic rx, n/v with po use, seizures with high

Page 63: NAPLEX Drugs Table

doses with renal insufficiencey, hematologic reactions, interstital neprhritis

UnasynAmpicillin/sulbactam

penicillin plus Beta lactamase inhibitor

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

ZosynPiperacillin/tazobactam

penicillin plus Beta lactamase inhibitor

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Timentinticarcillin/clavulanic acid

Penicillin plus beta lactamase inhibitor

allergic rx, n/v with po use, seizures with high doses with renal insufficiencey, hematologic reactions, interstital neprhritis

Zyvox Linezolidgram positive antibiotic

hematologic effects, MAO inhibition

Page 64: NAPLEX Drugs Table

SynercidQuinupristin/dalfopristin

gram positive antibiotic

thrombophlebitis, hyperbilirubinemia, arthralgias/myalgias

Vancocin vancomycingram positive antibiotic

nephrotoxicity, ototoxicity, thrombophlebitis, red-man syndrome

Penetrex enoxacin fluoroquinolone

N/dyspepsia, HA, insomnia, Qt prolongation, photosensitivity,

Tequin gatifloxacin fluoroquinolone

N/dyspepsia, HA, insomnia, Qt prolongation, photosensitivity,

Maxaquin lomefloxacin fluoroquinolone

N/dyspepsia, HA, insomnia, Qt prolongation, photosensitivity,

Avelox moxifloxacin fluroquinolone

N/dyspepsia, HA, insomnia, Qt prolongation, photosensitivity,

Noroxin norfloxacin fluroquinolone

N/dyspepsia, HA, insomnia, Qt prolongation, photosensitivity,

Zagam sparfloxacin fluroquinolone N/dyspepsia, HA, insomnia, Qt prolongation,

Page 65: NAPLEX Drugs Table

photosensitivity,

Trovan trovafloxacin fluoroquinolone

N/dyspepsia, HA, insomnia, Qt prolongation, photosensitivity,

Cinoxacin, Cinobac

cinoxacin quinoloneno gram positive activity, only for GU and Gi tracts

NegGram nalidixic acid quinoloneno gram positive activity, only for GU and Gi tracts

Declomycin demeclocycline tetracycline

photosensitivity, not in children <8, hepatotoxicity, N/D/A

Methacycline methacycline tetracycline

photosensitivity, not in children <8, hepatotoxicity, N/D/A

Terramycin Oxytetracycline tetracycline

photosensitivity, not in children <8, hepatotoxicity, N/D/A

Achromycin V, Sumycin, Tetracyn

tetracycline tetracycline

photosensitivity, not in children <8, hepatotoxicity, N/D/A

Sulfadiazine sulfadiazine sulfonamidehypersensitivity, dermatologic rxns

Urobiotic sulfamethizole sulfonamidehypersensitivity, dermatologic rxns

Page 66: NAPLEX Drugs Table

SpetraSulfamethoxazole

sulfonamidehypersensitivity, dermatologic rxns

Gantrisin sulfisoxazole sulfonamidehypersensitivity, dermatologic rxns

Primaxinimipenem/cilastatin

antibioticgi adverse effects, hematologic rxns, seizures

Fungizone amphotericin B antifungal agent

fever, chills, hypotension rigors, upton infusion, nephrotoxicity, hematologic effects

Cancidas caspofungin antifungal agenthepatic effects, sensitivity rxns, infusion rxns

Ancobon flucytosine antifungal agent

gi effects, hepatic effects, renal effects, nervous system effects, sensitivity rxns

Fulvicin P/G griseofulvin antifungal agent

paresthesias of hands and feet after prolonged therapy, epigastric pain, N/V/D/gas, lupus like rxn

Mycostatin nystatin antifungal agentmild nausea and diarrhea

Lamisil Terbinafine antifungal agent haptic failure, anaphylactoid rxn, SJS, erythema

Page 67: NAPLEX Drugs Table

multiforme

Vfend voriconazole antifungal agent

hepatitis, cholestasis, anaphylactoid rxn, SJS, photosensitivity

Sporanox itraconazole antifungal agent

n/v/d/gas, SJS, chf, edema, prolonged QT interval, increased LFTs

PaserAminosalicylic acid

antitubercular agent

N/V/D/A, vitamin B12, folic acid, and iron malabsorption

Myambutol ethambutolantitubercular agent

ocular effects, loss of red-green color discrimination

Isoniazid isoniazid (INH)antitubercular agents

peripheral neuritis, rarely seizures, increases in bilirubin, AST and ALT, hematologic effects

Pyrazinamidepyrazinamide (PZA)

antitubercular agents

increased liver enzymes, gout

Rifampin rifampinantitubercular agents

n/v/d, increased bilirubin, AST and ALT

Ritalin, Methylin,

methylphenidate

Stimulant anorexia, abdominal pain,

Page 68: NAPLEX Drugs Table

Metadate ER, Concerta

HA, insomnia, jitteriness, social withdrawal, transient motor tics, wt loss

Dexedrine, Dextrostat, Adderall, Xr

amphetamine Stimulant

anorexia, abdominal pain, HA, insomnia, jitteriness, social withdrawal, transient motor tics, wt loss

Focalin

D-threo-enantiomer of racemic methylphenidate, dexmethylphenidate

Stimulant

anorexia, abdominal pain, HA, insomnia, jitteriness, social withdrawal, transient motor tics, wt loss

Strattera atomoxetine Stimulant

anorexia, abdominal pain, HA, insomnia, jitteriness, social withdrawal, transient motor tics, wt loss

Cognex tacrineAlzheimer's disease tx

(blank)

Aricept donepezilAlzheimer's disease tx

N/V

Exelon rivastigmineAlzheimer's disease tx

N/V, gi upset, sig wt loss

Razadyne galantamine Alzheimer's n/v, gi upset

Page 69: NAPLEX Drugs Table

disease tx

Sinemetcarbidopa/levodopa

Parkinson's disease tx

take on empty stomach, n/v, agitation, depression

Parlodel bromocriptineParkinson's disease tx

n/v, agitation, depression

Permax pergolide parkinson's dz tx

N/V, agitation, confusion, depression, dyskinetic movts

Mirapex pramipexole parkinson's dz tx

N/V, agitation, confusion, depression, dyskinetic movts

Requip ropinirole parkinson's dz tx

N/V, agitation, confusion, depression, dyskinetic movts

Eldepryl, Carbex, Atapryl, Selpak

selegiline parkinson's dz tx

N/V, insomnia, dizziness, agitation, anorexia, dyskinetic movts

Comtan entacapone parkinson's dz txN/VD, dyskinesia, urine coloration

Tasmar tolcapone parkinson's dz txN/VD, dyskinesia, urine coloration, liver toxicity

Symmetrel amantadine parkinson's dz tx confusion, dizziness, depression,

Page 70: NAPLEX Drugs Table

anxiety, insomnia, psychoses

Cogentin benztropine parkinson's dz tx

anti SLUD, confusion, agitation, psychoses

Artane trihexyphenidyl parkinson's dz tx

anti SLUD, confusion, agitation, psychoses

Ocupress Carteolol Glaucoma Tx (blank)

Betagen levobunolol Glaucoma Tx Nonselective

OptiPranolol metipranolol Glaucoma Tx Nonselective

Betoptic betaxolol Glaucoma Tx B1 antag

Betaxon levobetaxolol Glaucoma Tx B1 antag

Diamox acetazolamide Glaucoma Txcarbonic anhydrase inhibitor

Trusopt dorzolamide Glaucoma Txcarbonic anhydrase inhibitor

Neptazane methazolamide Glaucoma Txcarbonic anhydrase inhibitor

Azopt brinzolamide Glaucoma Txcarbonic anhydrase inhibitor

Xalatan latanoprost Glaucoma Txprostaglandin analog

Page 71: NAPLEX Drugs Table

Lumigan brimatoprost glaucoma txprostaglandin analog

Travatan travoprost glaucoma txprostaglandin analog

Rescula unoprostone glaucoma txprostaglandin analog

Alphagan brimonidine gluacoma txalpha2 adrenergic agonist

Propine dipivefrin gluacoma txalpha adrenergic agonist

Pilocar, Ocuserts

pilocarpine glaucoma tx cholinergic, miotic