new york city bioscience cluster

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New York City Bioscience Cluster January, 2009

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New York City Bioscience Cluster

• Science

• Talent

• Funding

• NYC Bioscience Community

• Real Estate– East River Science Park

– BioBAT

– SUNY Downstate

– Audubon

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ence

Variety of FundingFunding SourcesLocal Financial Institutions

$1.3B in NIH funding annually

Financial Capital of the World

NYC Investment Fund

134 Venture Capital Firms investing in Life Sciences

QETC Programs

Large TalentTalent Pool#1 metro area bioscience employment

122 Nobel Prize Winners

31 Howard Hughes Investigators

427,300 Metro Healthcare Employees

More College Students Than Any City

Science Science - Academic Medical CtrsLargest Concentration of AMCs

#2 City For NIH Funding

New York University

Memorial Sloan Kettering

Mount Sinai School of Medicine

Columbia University Medical Center

Einstein Medical Center

The Rockefeller University

Weill Cornell Medical College

Hospital for Special Surgery

SUNY Downstate

World-Renowned Research Institutions

26 Research Centers

58 Hospitals

Entrepreneurial EnvironmentEntrepreneurial Environment

125 bioscience Companies

Pharma HQ - Pfizer, BMS, Forest, Imclone

Top Business Schools

20 AMC Spin-Offs Annually

#1 in Patent Activity

NYCBIO, Lab 2 Wallstreet

Industry AssociationsNew York Academy of Sciences (NYAS)

Greater New York Hospital Association (GNYHA)

NY Structural Biology Center (NYSBC)

Lab SpaceEast River Science Park

BioBAT

Audubon


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NYC is Home to Small Biotech and Large Pharmaceutical Companies

New York City Major Pharmaceutical Companies

Company Headquarters Address # of Employees

Pfizer Inc.Yes

235 E. 42nd St. New York, NY 10017

4,500

Bristol Myers- Squibb Company

Yes345 Park Ave. New York, NY 10154

1,200

Forest Laboratories, Inc.

Yes909 3rd Ave. New York, NY 10022

227

ImClone Systems, Inc. Yes

180 Varick St. New York, NY 10014

180

Source: Hoovers

Over 125 bioscience companies are located in NYC

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New York City is Second in the Country in NIH New York City is Second in the Country in NIH FundingFunding

In FY2007, New York City received $1.3 billion in NIH research grants, second in the country only to Boston

Source: National Institutes of Health, FY 2007 Awards

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0.73

0.78

0.78

1.3

1.6

0 0.2 0.4 0.6 0.8 1 1.2 1.4 1.6

Seattle

Baltimore

Philadephia

New York City

Boston

FY 2007 NIH Awards, Top 5 Cities / Billion

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NYC Ranks # 2 in NIH Funding

Sample Institutions: NIH Funding 2007 FY

Columbia University

Mount Sinai School of Medicine

$339.8M

New York University School of Medicine

Albert Einstein College of Medicine

Weill Medical College of Cornell

MSKCC


Total NYC NIH Funding FY 2007: $1.3 B

$175.7 M

$153.1 M

$132.4 M

$114.5 M

$110.7 M

Rockefeller University

$71.6 M

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NIH Funding: New York CityNIH Funding: New York City’’s Higher Education s Higher Education Institutions Lead the CountryInstitutions Lead the Country

New York City leads the country in NIH funding for Universities and Colleges


$747,715,135

$590,604,297

$515,707,015

$427,302,032

$1,054,643,499New York City

Baltimore

Philadelphia

Boston

Seattle

FY 2007 Universities & Colleges NIH Funding Ranking by City

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New York City Has the Highest Concentration of Academic Medical Centers in the Country

• Ranked 20th in the country by the NIH

• School invested $179M in 2007 to support education, research, and patient care initiatives

• Will establish 12 new research institutes1

New York University School

of Medicine

Albert Einstein College of Medicine

Columbia University Medical

Center

Mt Sinai School of Medicine

Memorial Sloan Kettering Cancer

Center

Hospital for Special Surgery

Weill Cornell Medical College

The Rockefeller University

SUNY Downstate Medical Center

1Brain Institute; Cancer Institute; The Zena & Michael A. Wiener Cardiovascular Institute; Institute For Child Health and Development; Emerging Pathogens Institute; Immunology Institute; Institute for Metabolic Disorders; Institute for Epidemiology, Biostatistics, and Prevention; Experimental Therapeutic Institute; Institute For Molecular Imaging; Charles R. Bronfman Institute For Personalized Medicine; The Black Family Stem Cell Institute2,Association of University Technology Managers, US Licensing Activity Survey, FY 2006

• Significant clinical breakthroughs include the first blood test for cancer, the first medical use of the laser, and the first successful transfer of genes from one cell to another

• 16 Nobel Prizes (2 current)• 2007 R & D of $585 M

• 376K sf of research laboratories • Launching 6 new Centers of

Excellence• Received contributions of over

$500M in 2008• Ranked #1 in patent revenue

during 2006 by Forbes

• 300 research laboratories • Runs one of the largest post-

graduate medical training programs in the US

• Opened a 223K sf biomedical research facility with 40 new labs

• Opened a 300,000 sf Research Center of laboratory space

• $184M Licensee income during 2004 – 20062

• Ranked #1 hospital in the US in orthopedics and fourth in rheumatology by U.S. News & World Report in 2008

• Pioneered the first total knee replacement

• World leader in orthopedic surgery, performing more than 20,000 procedures per year

• 69 research laboratories• Scientific staff includes 6 Nobel

Laureates, 7 recipients of Albert Lasker Medical Research Awards, 35 members of the National Academy of Sciences, 3 recipients of the MacArthur Foundation “genius grants”, 2 recipients of the National Medal of Science

• Developed world’s first gene therapy for Parkinson’s Disease

• First successful embryo- biopsy pregnancy and birth in the US

• First indication of bone marrow’s critical contribution to tumor growth

• 75 community outreach programs

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• Science

• Talent

• Funding



– BioBAT

– SUNY Downstate

– Audubon

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The New York City Region Has the Highest Employment in Biosciences in the Country

35,083

42,323

46,000

53,036

66,158

110,596

San Francisco-Oakland-Fremont, CA

Boston-Cambridge-Quincy,MA-NH

Chicago-Naperville-Joliet, IL-IN-WI

Philadelphia-Camden-Wilmington, PA-NJ-DE-MD

Los Angeles-Long Beach-Santa Ana, CA

New York-N. New Jersey-LongIsland, NY-NJ-PA

Total Employment in the Biosciences for the largest Overall Metro Regions

Source: “Growing the Nation’s Bioscience Sector: State Bioscience Initiatives 2006” A Battelle Technology Partnership Practice report prepared for the Biotechnology Industry Organization (BIO), January 2007 Battelle calculations based on Bureau of Labor Statistics, QCEW program data from the Minnesota IMPLAN Group

The New York City Metro Region is ranked #1 in Bioscience employment in 2006

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Distinguished Life Sciences Faculty

Chemistry: 2008 Discovery and Development of Green Fluorescent Protein, GFP Martin Chalfie, Columbia University

2003 Structural and Mechanistic Studies of Ion Channels Roderick MacKinnon, Rockefeller University/HHMI

Physics: 1998 New Form of Quantum Fluid with Fractionally Charged ExcitationsHorst L. Stormer, Columbia University

Physiology 2001 Key Regulators of the Cell Cycle or Medicine: Paul M. Nurse, Rockefeller University

2000 Signal Transduction in the Nervous SystemPaul Greengard, Rockefeller University/HHMIEric Kandel, Columbia University (P&S)/HHMI

1999 Intrinsic Signals in Proteins Govern Transport & Localization in CellGunter Blobel, Rockefeller University/HHMI

1998 Nitric Oxide as Signaling Molecule in Cardiovascular SystemRobert F. Furchgott, SUNY Downstate (Emeritus)

1989 Cellular Origin of Retroviral OncogenesHarold E. Varmus, Memorial Sloan-Kettering Cancer Center

Selected Nobel Laureates at New York City Research Institutions

Paul Greengard & Eric Kandel

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122 Nobel Laureates Trace their Roots to New York City

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New York Metro Region Has Large, Skilled Scientific & Healthcare Workforce

Source: U.S. Dept of Labor, Bureau of Labor Statistics, May 2007

§Metro Region

Healthcare Practitioners &

Technical Occupations

New York/North Jersey/ LI

427,300

Philadelphia/ South Jersey

162,890

Boston/Cambridge/ Quincy 112,620

Washington DC/Arlington / Alexandria 112,540

San Francisco/ Oakland 83,210

San Diego / Carlsbad 56,390

Raleigh- Durham Chapel Hill 45,670

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The Most Educated, Talented Workforce in the U.S.

Population with Bachelor's or Higher Degree

43

134

150

151

180

193

203

268

273

463

589

1,447

Cambridge

Boston

Washington, DC

San Antonio

Phoenix

Seattle

Dallas

San Francisco

San Diego

Chicago

Los Angeles

New York City

Almost 5 million people over the age of 25 in the New York metropolitan area - more than a third of the region’s population - had at least a bachelor’s degree in 2005, according to the latest data from the Census Bureau. In Manhattan, nearly three out of five residents were college graduates and one out of four had advanced degrees, forming one of the highest concentrations of highly educated people in any American city.Source: The New York Times, August 2006

Source: 2000 U.S. Census. Figures in thousands

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More than half a million students attend the 110 institutions of higher education in New York City, making it the biggest college town in the country.Source: Crain’s New York, August 2009

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• Science

• Talent

• Funding



– BioBAT

– SUNY Downstate

– Audubon

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New York City Is The WorldNew York City Is The World’’s Financial Capitals Financial Capital

$110M NYCIF

Investment

New York State QETC Incentives

Over 100 VC firms investing in Life Science

Top 4 region for VC

Investment $1.9 B in academic R&D expenditures

annually

Over 30 Technology VC

firms

Millions spent annually on Technology investment from Angel Investors

Fund

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• Science

• Talent

• Funding



– BioBAT

– SUNY Downstate

– Audubon

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Building the Community: New York City Bioscience Initiative and NYCEDC Websites

• Provide important information

• Build a community

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Building the Community: NYC Bioscience Bulletin

• Over 5,000 subscribers worldwide

• Highlights commercial and scientific activities of NYC based companies

• Showcase NYC bioscience companies

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• Science

• Talent

• Funding



– BioBAT

– SUNY Downstate

– Audubon

2020

• 4.7-acre site on City-owned property

• Located at 29th St and 1st Ave between Bellevue Hospital and NYU Medical Center

• 1.1 Million sf (92,900m2) permitted for R&D and related office space in 3 buildings

• Situated in First Avenue medical corridor near several major research hospitals

• Future home to pharma, bioscience, technology, & medical device companies and VCs, IP attorneys and other related service providers

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East River Science Park

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• 4M SF overall

• BioBAT resides within Building A on the 97- acre site in Sunset Park, Brooklyn

• Initial tenant – IAVI

• Phase 1 tenants include SUNY Downstate and commercial bioscience lab space

• Located 45 minutes via subway to Midtown Manhattan

• EDC is holding significant space (400,000+ sf) for future bioscience development

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Brooklyn Army Terminal

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• Commercial R&D facility in Brooklyn

• 24,000-sf lab/office space with additional 12,000-sf under construction

• Located on SUNY Downstate Medical Center Campus

• 25 minutes to Manhattan via subway

• Has 14,000-sf of equipped chemistry lab space available

• Tenants include: Biosignal, BioCangen, IAVIRea

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SUNY Downstate Biotechnology Incubator

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• Commercial R&D facility in Manhattan

• Audubon I: 50,000sf of wet lab space

• Currently home to 15 biotech companies - 100 % occupied

• Located adjacent to Columbia University College of Physicians and Surgeons and New York Presbyterian Hospital

• 15 minutes via subway to Midtown Manhattan

• Tenants include: Intra-Cellular Therapeutics, Forticell Bioscience, Nephros, Oligomerix, NanIRX

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Audubon Business & Technology Center

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Lenzie HarcumVice President, BiosciencesNYC Economic Development Corp.(212) [email protected]

NYC Bioscience Cluster

new york city bioscience cluster

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