nhp002 [5.5 ± 1.24%]
DESCRIPTION
A). Immunosuppression period. ***. 18. 16. *. 14. Hepatic PBGD activity (pmol URO/mg prot/h). 12. Normal range. 10. 8. 6. weeks. 0. 5. 10. 15. 20. 25. NHP001 w/o IS. NHP002 with IS. NHP003 with IS. **. 25. 20. PBGD expression mRNA (arbitrary units). 15. **. 10. *. - PowerPoint PPT PresentationTRANSCRIPT
C)
NHP002[5.5 ± 1.24%]
NHP003[2.2 ± 0.47%]
A)
NHP001[2.2 ± 0.37%]
B)
x200 x200 x200 x200x200 x200
NHP001 w/o IS
NHP002 with IS
NHP003 with IS
Immunosuppression period
weeks6
8
10
12
14
16
18
0 5 10 15 20 25
He
pa
tic
PB
GD
ac
tiv
ity
(pm
ol
UR
O/m
g p
rot/
h) ***
*
Normal range
0
noninjected
(n=4)
NHP001
NHP002
NHP003
**
*
0
5
10
15
20
25
PB
GD
exp
ress
ion
mR
NA
(ar
bit
rary
un
its)
**