node.health and evidence based digital medicine12+ ambulatory surgical centers 200+ community...
TRANSCRIPT
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NODE.Health and
Evidence Based Digital Medicine
Ashish Atreja, MD, MPHChief Innovation Officer, Medicine
Assistant Professor and Director, Sinai AppLab
Icahn School of Medicine at Mount Sinai, New York, NY
© Icahn School of Medicine at Mount Sinai
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Mount Sinai Health System
Founded in 1852Not-for-profit Academic Medical Center
7 Hospitals, 1 Medical School, 15 Institutes
3500+ beds, 135 operating rooms
12+ Ambulatory Surgical Centers
200+ community location around New York
36,000 employees
6,200 physicians; 2,000 residents2.6 million outpatient visits
500 thousand ER visits
170 thousand inpatient visits
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This is our Burning Platform
Courtesy Mike Berger
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Value based healthcare is real!
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Health Systems Unprepared for
Value Based Care
Value based
care has
arrived
50% of unprepared
for bundles and
MACRA
76% of hospitals
face readmissions
penalties
http://khn.org/
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Mount Sinai Readmission penalties
Advisory Board, Courtesy: Robby
Freeman
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7Accenture, 2016
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http://blog.tauedu.org/medical-jokes-doctor-and-patient
We need tools to
address
triple whammy!!!
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Going beyond the EHRs to find an Answer to
Value-Based HealthCare
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Computers are like a bicycle for the mind..
▶ I think one of the things that really
separates us from the high primates
is that we’re tool builders. Humans
are one of least efficient species
when it comes to using energy to
move a kilometer. But, a human on
a bicycle, blew the comparison
away, completely off the top of the
charts- Steve Jobs
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Emergence of the new field of Digital Medicine265,000 Mhealth Apps
Telemedicine
Linked Wearables
AI/Machine Learning
Secure Messaging
Augmentic/ Virtual Reality
Voice commands/ Alexa
Chat Bots
Exposome
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Digital Medicine App Landscape
mHealth economics
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In RCT, patients using BlueStar saw a greater mean A1c
decline than those receiving usual care: 1.2% (1.9% vs
0.7%) over a 12 month period
Quinn, C et al, Diabetes Care, 2011
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Telemedicine becomes mainstream:
46 states now have some sort of Parity Law
A significant reduction in emergency department visits (OR = 0.27) and
hospitalization (OR = 0.46) was reported with telehealth care in COPD patients
McLean S Br J Gen Pract, 2012
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From: Effect of Lifestyle-Focused Text Messaging on Risk Factor Modification in Patients With Coronary Heart
Disease: A Randomized Clinical Trial
JAMA. 2015;314(12):1255-1263. doi:10.1001/jama.2015.10945
Enrollment of Participants in the TEXT-ME Randomized Clinical TrialLDL-C indicates low-density lipoprotein cholesterol.
Figure Legend:
At 6 months, levels of LDL-C were significantly
lower in intervention participants (mean
difference, −5 mg/dL with reductions in systolic
blood pressure (−7.6 mm Hg) and BMI (−1.3),,
and a significant reduction in smoking (26% vs
44%; relative risk, 0.61 [95% CI, 0.48 to
0.76]; P < .001).
The majority reported the text-message program
to be useful (91%), easy to understand (97%),
and appropriate in frequency (86%).
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2016: Year of Wearables / Implantables / digestibles
mHealth + Telehealth World Congress, 2015
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Somatix (Wearables)
www.somatixinc.com
Somatix is a behavioral
medication software platform,
utilizing real-time
interventions based on data
gathered from standard
wearables. Its first product,
SmokeBeat is addressing the
global smoking cessation
market; its customers include
corporate employers, health
insurance companies and
clinics
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From Quantified Self to Quantified Population Health
Angarita et al. Quantified Self
Swan M, Big Data, 2013
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Envisioning digital care in year 2020
✓ Virtual care (telemedicine and messaging)
✓ 24/7 tracking (remote monitoring)
✓ Population health (predictive analytics)
✓ Empowerment (SDH, peer networking)
✓ Prescribing Apps (AR/digital therapeutics)
@ Fraction of Cost and Time
Paul Sonnier, Storyofdigitalhealth.com
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How do we get there?Build Capacity for Digital Transformation
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“The Digital Daisy”
Digital
Experience
Digital
Gateway
Telemedicine
mHealthData
Analytics
Innovation
Courtesy Bruce Darrow and Digital
Medicine Advisory Team
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Sinai App Lab: Joint initiative of DOM with IT and Innovation Partners
Apps Registries QI dashboard CER Trial recruitment
AppLab: Academic Research Organization in Digital Medicine
MISSION
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The Multiplier EffectProviders
ResearchersPop Health
& ACO
Patients
MSIP IT DOM CTSA
25 funded Projects, 100 investigators served, Digital Medicine Community created
CollaboratorsThe Team
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Remote Monitoring in IBD: HealthPROMISE
Atreja A, JMIR Res Protocol, 2015
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Realtime population health dashboard w/ app data
© Icahn School of Medicine
at Mount SinaiRegistration: ClinicalTrials.gov NCT02322307
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Improvement in QOL and Quality Indicators in
IBD with HealthPROMISE
Atreja A, DDW, San Diego. 2016
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Fatigue and Tension as major drivers of poor quality of life in more than 75% of IBD patients
Mount Sinai patients with app and UPMC patients with paper based survey
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Singular Platform for Digital Transformation
Health Education Content, Videos, Webinars
Survey and Feedback
Tracking Apps, Websites
Wearables
Telemedicine
Appointment Scheduling
Social Patient Engagement
Clinical Trials
Specialty Specific customized solutions for patient care and research
https://www.youtube.com/watch?v=1Ax926yrEQc
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The Time for Prescribing Apps has Come!!
30
NPR Marketplace: An App to Prescribe other Healthcare Apps!!
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RxUniverse: Usability and Learnability
AMIA, 2017
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PI: Guy Montgomery
Julie Schnur
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Validated Use-CaseReadmission Reduction
Through the use of the mobile application, HeartHealth, healthcare providers are able to remotely monitor their patients’ blood pressure and weight in the 30 day high risk period post discharge.
Pinney S, et al. | Use of Electronic Patient Reported Outcomes and Automated Devices for Heart Failure Disease Management | iproc 2017;3(1):e24 | URL: http://www.iproc.org/2017/1/e24 | DOI: 10.2196/iproc.8459
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Enterprise-wide SDoH Assessment
EPIC_view copy.png
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Real Time Patient Experience Survey and Service Recovery (MIPS)
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CLINICAL DECISION AID:
BLADDER CANCER RISK TOOL (OCM)
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Peri-procedural Support for Bundles
Needs to get cleaned up
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Exponential ROIOne Stop Shop for Multiple Transformation Use-Cases
EHR IntegratedPlatform
Curated by Academic Centers
Increased Patient and Provider Engagement
Improved Patient Outcomes
TransformingOrganizations within
90 days
ROI through
Leveraging investments made (PHR)
Improving peri-op throughput
Remote monitoring and CCM Codes
Patient experience survey and
Real time service recovery
Reducing readmission penalties
MACRA-Increased score- QI activities
CIN and Pop Health (Top 5 diseases)
At-risk contracts and ACO
Ongoing Use-cases
o Providing PHR access to populations at scale
o Behavioral health apps
o Pre and Post Surgery Engagement
o Transitions of Care
o Remote Monitoring of 5 high cost diseases
o Employee Engagement and Wellness
o Assess Social Determinants
o Readmission Reduction
o Patient Reported Outcomes
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Tsai et al. PLOS Medicine. Scaling up mHealth: Where is the evidence?
BOTTLENECK : Creating
Evidence for Digital Medicine
INNOVATION
EVIDENCE
IMPLEMENTATION
mHealth Lacks Evidence:
Takes “scatter shot” approach
--World Bank
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Digital Health Investment fueled by Innovation
Economy
41
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Problem of Plenty
42
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“In the wake of reports that question the
accuracy and effectiveness of
[Theranos’] technology… health-tech
companies will now face a greater
burden of proof to demonstrate that
their technology is effective.”
The ‘Burden of Proof’
Future generations of startup founders should ensure they are working with
venture capital firms that have ample experience in health care. These
investors will understand that it takes time to build a successful and long-
lasting company.”
- Christina Farr, Fast Company
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https://peerj.com/articles/1554/
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Evidence-Based Digital Medicine
(EBDM)
RIGOR
Evidence-based Medicine
INNOVATION
Digital Technologies
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NODE Health: Guiding Principles
1. Share information about ongoing innovation and single site trials
2. Standardize existing governance,regulatory and best practices
3. Support multi-site digital medicine trials and implementations
2.Transformation Challenge1. Evidence Challenge
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48
Hospital
System &
Patients
Startup
Grant
Agency
Industry
Pharma
Payer
VC and
Angel
NODE Health Foundation
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Launched Feb 2016
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Executive Board
Megan
HealthIm
pact
Sameer
Badlani
Sutter
Health
Sarah
Zweifach
John
Sharp
BrianLifeBridge Health
Jay
Modus
Moiz
Kasubhai
Lincoln
Hospital
Dr. Yauheni Solad
Yale New HavenVickie
Tiase
Dr. Jeet Barmecha
SBH
Health
Dr. Amy
Sheon
Dr Aenor Sawyer
UCSF
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Consortium Members
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Eco-System Members and Partners
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Sharing Evidence
Peer Reviewed EBDM
Newsletter
Curated by thought
leaders
Initiatives, reviews, key
publications
7000+ members
#digmedevidence
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JOURNAL
Partnership
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2018 Focus Areas
I. Meaningfully Engaging
Underserved Population
I. Successful transformation
examples from payers and
health systems
I. Enabling clinical trials and
evidence generation
Click here
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Collaborators
Executive Sponsors: Bruce Sands, Barbara
Murphy, Bruce Darrow, Kumar Chatani
INTERNAL Collaborators
HealthPROMISE: IBD Center
IBD Home- Laurie Keefer
Heart Health: Sean Pinney, Robbie Freeman
Hepcure: Ponni Perumalswami, Jeff Weiss
HP Survey: Roxanna Mehran
HealthFlo: Beth Raucher, Andrew Dunn, Julie
HP Allergy: Scott Sicherer
Bladder Cancer: Matt Galsky
Health Hypnosis: Guy Montgomery
Patient Satisfaction: Mona Krouss
eMotivate: Sarah Miller
Bifurcate: Annapoorna Kini
Procedure Bundle: David Greenspan, Brett
Bernstein
Care Management: Lisa
Clinical Operations: Abbie Schwartz
TEAMS
DOM: Office of Innovation: Noel Rijo
Mount Sinai Innovation Champions
Clinical Informatics: Bruce Darrow
ehealth Team: Sudipto Srivastava
Big Data Team- Robbie Freeman
Telemedicine: Niyum, Sudipto, Nick Genes
MSIP: Scott Friedman, Erik Lium
CTSA: Janice Gabrilove, Carol Horowitz
EXTERNAL Collaborators
Gett- New York State- Mark Thompson
Canada PACE sites: Neeraj Narula
Mc Gill University: Waqqas Afeef
Baystate Health: Rohit Singhania
Yale: Yoeheni Solad
UPMC: Eva Szigethy
Northwestern-Stephen Hanauer
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Digital Medicine is Digital Medicine
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