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Page 1: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction
Page 2: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction
Page 3: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction
Page 4: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Not a response to reward itself, but to information about reward

• More than predicted in ‘previous state’= increased activity; positive prediction error

• Less than predicted in ‘previous state’= reduced activity; negative prediction error

Page 5: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction
Page 6: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Invasive techniques

Electrode in the brain: while undergoing neurosurgery

Page 7: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Some applications

Page 8: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Diagnosis

Page 9: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Brain-Machine Interface

Page 10: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

[ TH : Tyrosine Hydroxylase ]

Neural grafting, with stem cells

Page 11: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Deep-brain stimulation

Page 12: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Self-stimulation of subthalamic nucleus (in the basal ganglia): Patients with Parkinson’s disease can move their arms and legs again

Page 13: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Cutting-edge science:

microscopic level of analysis,using optogenetics

Page 14: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Use genetic markers to identify specific neurons in the living brain;Study their relation to behavior

Page 15: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction
Page 16: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction
Page 17: Not a response to reward itself, but to information about reward More than predicted in ‘previous state’ = increased activity; positive prediction

Conclusion:

Lots of interesting work left...You should consider doing it...


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