nutraceuticals and-functional-foods. farwa hussain

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NUTRACEUTICALS AND FUNCTIONAL FOODS

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Page 1: Nutraceuticals and-functional-foods. farwa hussain

NUTRACEUTICALS AND FUNCTIONAL FOODS

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ByFarwa Hussain Roll No. 04Farzana Nazar Roll No. 06

Sana Sharif Roll No. 11Faryal Faiz Roll No.13

Salma Ahmad Roll No.20

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IntroductionNeed for nutraceuticals

Categories of nutraceuticalsClassification of nutraceuticals

examplesAdvantagesLimitations

Effectiveness and safety regulationsBioavailability

Safety and efficacyLabelling and health claims

Conclusion

CONTENTS

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INTRODUCTIONThe term “Nutraceutical” was first coined by Dr.

Stephen L. Defelice as “a product isolated orpurified from foods and sold in medicinal forms.

They have physiological benefit”

NUTRACEUTICALS

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Nutraceutical is a combination of 2 words1. Nutrition and

2. Pharmaceutical.

Nutraceuticals are food product that provides health aswell as medical benefits; including the prevention and

treatment of disease.

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Consumers are deeply concerned about how their health care is managed, administered and priced. They are

frustrated with the expensive, high tech, disease treatment approach predominant in modern medicine and are therefore seeking for complementary or alternative

beneficial products

NEED FOR NUTRACEUTICALS

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Phytochemicals and antioxidantsare two specific types of nutraceuticals. Research has

proved that foods with phytochemicals may help toprovide protection from diseases such as cancer,diabetes, heart disease, and hypertension, e.g.

carotenoids found in carrots.

PHYTOCHEMICALS AND ANTIOXIDANTS

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Antioxidants may behelpful in avoiding chronic diseases, by preventing

oxidative damage in our body.Over the last 20 years,

numbers of Nutraceuticals are available for selfmedication or for sale.

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There has been a boom in sale of Nutraceuticalbecause of -1. Adverse effects of pharmaceuticals

2. Increased tendency of patients for self-medication3. Aging population e.g. - arthritis

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Nutraceuticals are non- specific biological therapies used to promote wellness, prevent malignant

processes and control symptoms. These can be grouped into the following three broad categories. 1)Nutrients: substances with established nutritional functions such as vitamins, mineral, amino acids and

fatty acids.2) Herbals: herbs or botanical products such as

concentrates and extracts

CATEGORIES OF NUTRACEUTICALS

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1)3) Dietary supplement: Reagents derived from other sources( Pyruvate, Chondrotin sulphate, steroid hormone

precursor) serving specific function such as sports, nutrients, weight loss supplements and meal replacement)

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Nutraceutical is a term used to describe productobtained from food sources that provides extra healthbenefits as well as basic nutritional value present in

food. There are different types of products that comesunder the class of nutraceuticals.

CLASSIFICATION OF NUTRACEUTICALS

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A dietary supplementis a product that contains nutrients derived from foodproducts .The "dietary ingredients" present in these

products are: metabolites, minerals, vitamins,herbs, and amino acids.

DIETARY SUPPLEMENTS:

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Functional foods aredesigned foods which provide enriched foods close to

their natural state to consumer, rather thanmanufactured dietary supplements in liquid or capsule

form. A process of making enriched food is calledNutrification.

FUNCTIONAL FOODS:

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Functional foods provide requiredamount of vitamins, fat, carbohydrate, amino acid etcto body.Established requirement that functional food

should possess are-(1) they should be in their naturally-occurring form,

(2) they should be an essential part of our daily diet,(3) should regulate a biological process in hopes of

preventing or controlling disease

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Improve health Delay aging

Increases life expectancy Reduced side effects with desirable

outcomes

ADVANTAGES OF NUTRACEUTICALS

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Not subjected to same testing and regulations as pharmaceuticals

Majority not regulated by FDA in USA Companies creating unregulated products to

create a wide profit margin Bioavailability of nutrients is lower

No regulatory definition Effect may be attributed to that of a placebo

LIMITATIONS

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Nutraceutical products also required same level of scrutiny and regulation as "dietary supplements". Companies which

involved in nutraceuticals production invest more on scientific research to substantiate their manufacturing

standards, products by keeping the view in mind consumer benefits and differentiate their products from "dietary

supplements ".

EFFECTIVENESS AND SAFETY REGULATION

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Now a day many international companies move within the industry, professional organizations, academia, and health

regulatory agencies to add specific legal and scientific criterion to the definition and standards for nutraceuticals.

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Bioavailability is "absorption rate" of a supplement product. In development of effective nutraceutical products

bioavilability play important role. The bioavailability of substance which is in natural state will be more as

comparison manufactured product.

BIOAVAILABILITY

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Nutraceuticals hold great potential, as an alternative to substance obtained by plant. Yet, some time they also cause

harmful effect as seen with ephedrine, a widely used botanical ingredient in weight-loss products. Now a days peoples are more conscious about there health and these products offer the promised health benefits. But danger is

associated with some product due to lake of solid information about interaction and side effect..

SAFETY AND EFFICACY

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Proper labeling and health claims are very important for nutraceutical products because they alert consumers.

Food and food substances can qualify for health claims only if they meet FDA requirements.

LABELING AND HEALTH CLAIMS

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1. FORTIFIED CEREALS-various cereals containvitamins and minerals.

2. VITAMIN AND MINERAL SUPPLEMENTS Vitamin A (Beta- Carotene),

3. ADDITIONAL SUPPLEMENTS-supplementsother than vitamin and minerals which have

beneficial effect on health for example-cod liver oil, primrose oil, glucosamine, garlic etc.

EXAMPLES OF NUTRACEUTICALS CURRENTLY

AVAILABLE IN MARKET-

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4. ENERGY DRINKS AND TABLETSTropicana,Minute Maid Pulp,Frooti

5. FOODS TO REDUCE CHOLESTEROLLEVELS-Abcor by Nutri-pharma, claimed toreduce cholesterol by 15-20% in 4 months.

6. PROTEIN POWDER Protinex(Dumex),GRD(Zydus), B.Protein

(British Biologicals)

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7. PRO-BIOTICS-Bacteria containing foods thatbelieved to improved health. For exampleYAKULT; contains

6.5 million lactobacilluscasei shirota, which is thought to improve gut

health.8. SPORTS PRODUCTS- Glucon-D (Heinz),

Glucose D (Dabur)

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Nutraceutical is growing health care industry in Pakistan.Nutraceuticals is playing important role in

developments of future therapeutics but it depends oncontrol of purity, efficacy and safety. Nutraceutical

products are used in prevention of disease not in cureof disease. Nutraceutical Products is collaborative

research effort of pharma, food and chemistry.

CONCLUSION

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Ashealthcare industry is growing in Pakistan growth of

nutraceutical is also increase because people want treattheir desease by improving their health with the help of

Fast Moving Healthcare Goods. Pakistan is significant

Player because it has extensive markets and facilitieslike rich bio-diversity, world-class R & D facilities,

resources, qualified human, and varied raw materials -aspects that provides edge our country.

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Now“nutraceutical a day may keep the doctor away”

replace the old proverb “an apple a day will keep thedoctor away” Consumers are turning massively to food

supplements to improve well being wherepharmaceuticals fail.

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1. Brower V., Nutraceuticals: poised for a healthyslice of the healthcare market?, Nat

Biotechnol., 1998, 16, 728-731.2. Cindy S. Oliveri, Nutraceuticals,

Phytochemicals, and Antioxidants-What AreThey All About, OSU Extension Fact Sheet,

2003, 5051-5098.3. Lockwood Brain, Nutraceuticals, second

edition, Pharmaceutical press. London, 2007,60-65.

4. pdfcast.org/search/all/nutraceutical-ppt5. Kalra E.K., Nutraceutical--definition and

introduction", AAPS Pharm Sci , 2003, 5, 27-28.

REFERENCES

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6. Hardy G., Nutraceuticals and functional foods:introduction and meaning, Nutrition, 2000, 16,

688.7. Ahmad, M.F., Ashraf S.A., Ahmad F.A., Ansari

J.K., and Siddiquee M.R.A., Nutraceuticalmarket and its regulation., Am. J. Food

Technol., 2011, 6, 342-347.8. Imanaga Y., Yoshifuji K,, Monose N.,

Metabolism of D-glucosamine, Koso., KagakuShimpoijuma, 1960,14,183-189.

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9. Ely A, Lock Wood B., What is evidence for thesafety and efficacy of dimethyl sulphoxide and

methylsulphonylmethane., pailief. Pharm J,2002, 269,685-687.

10. Grunler J, Dallner G., Ivestigation of regulatorymechanism in co-enzyme Q metabolism,

Method Enzymol.,2004,3-1711. Evans AM, Fornasini G., Pharmacokinetics of

L-carnitin, Clin. Pharmacokinet., 2003, 42,941-967.

12. Alhassane Touré , Xu Xueming, Flaxseedlignan source Biosynthesis, Metabolism,

Antioxidant Activity, Bio-Active Components,