nutraceuticals in dietary therapy copy
TRANSCRIPT
BY :-ANAS HARUNA INDABAWADEPARTMENT OF PHARMACY
SHIATS.
INTRODUCTIONAbout 2000 years ago, Hippocrates correctly
emphasized “Let food be your medicine and medicine
be your food". Currently there is an increased global
interest due to the recognition that “nutraceuticals” play
a major role in health enhancement. The term
"Nutraceutical" was coined by combining the terms
"Nutrition" and "Pharmaceutical" in 1989 by Dr
Stephen Defelice, Chairman of the Foundation for
Innovation in Medicine.
“Nutraceutical” is any substance that may be
considered as a food or part of food and provides
medical or health benefits, encompassing,
prevention and treatment of diseases.
Such products may range from isolated
nutrients, dietary supplements and diets to
genetically engineered "designer" foods, herbal
products and processed foods such as cereals,
soups and beverages.
NUTRACEUTICALS AND DISEASESNutraceuticals have been claimed to have a
physiological benefit or provide protection against the following diseases(and/or found to act as)
Cardiovascular agents
Anti-obese agents
Anti-diabetics
Anticancer agents
Immune boosters
Chronic inflammatory disorders
Degenerative diseases
1.Cardiovascular diseasesCardiovascular diseases (CVD) is the
name for the group of disorders of the heart
and blood vessels and include hypertension
(high blood pressure), coronary heart disease
(heart attack), cerebrovascular disease (stroke),
heart failure, peripheral vascular disease, etc.
Flavonoids are widely distributed in onion, cruciferous vegetables, black grapes, grapefruits, apples, cherries and berries. All these plays an important role in curing cardiovascular diseases.
Milk and eggs are the important animal sources of nutraceuticals, like proteins and polyunsaturated fats or essential fatty acids (EFAs). EFAs are required for production and rebuilding of cells, to reduce blood pressure, lower cholesterol and triglycerides,
Apple
Grapes Cherry
Onion
Milk
Egg
2- ObesityObesity, defined as an unhealthy amount of
body fat. It is a well-established risk factor for
many disorders like angina pectoris, congestive
heart failure, myocardial infarction ,
hypertension, hyperlipidaemia, respiratory
disorders, renal vein thrombosis, osteoarthritis,
cancer, reduced fertility etc.
One of the primary causes of rapid rise in obesity
rates is the increased availability of high-fat,
energy-dense foods.
A healthy diet can help in the following cases:
– Low fat diet may reduce the risk of heart
disease, diabetes and high blood pressure.
– A diet rich in fruits and vegetables provides
antioxidants (vitamins C, E and beta-carotene)
that protect the body against damage from free
radicals and reduces the risk of heart disease.
– Omega-3 and Omega-6, which are contained
in polyunsaturated fats (flax seeds, soybeans,
nuts and fish), may have a protective effect
against heart disease caused by obesity
Flax seed Soybeans
3- DiabetesDiabetes mellitus is characterized by
abnormally high levels of blood glucose, either
due to insufficient insulin production, or due to
its ineffectiveness.
In other words, we can say that diabetes is
a continual metabolic disorder that prevents the
body from utilizing glucose totally or partially.
Causes of Diabetes
-Insulin-dependent diabetes mellitus is mostly
outcome of a virus-initiated autoimmune destruction
of beta cells in the pancreas.
-Non-insulin-dependent diabetes mellitus can be
inherited and surface up with age or factors like
obesity, diet, lifestyle, inactivity, etc.
following are some dietary remedies to keep
control for diabetes like: beans, fish, citrus paradisi,
indian goose berry, string bean pod tea, red grape
fruit, blue berry, etc.
Citrus paradasi Beans
Indian gooseberry
4- CancerIn the year 2000, malignant tumours were
responsible for 12 percent of the nearly 56 million
deaths worldwide from all causes. According to the
World Cancer report, cancer rates would be 15 million
new cases in the year 2020 i.e. a rise in 50%. Cancer
has emerged as a major public health problem in
developing countries.
Cancer is a group of diseases involving
abnormal cell growth with the potential to invade or
spread to other parts of the body.
Dietary recommendations for cancer
prevention typically include an emphasis on
vegetables, fruit, whole grains and fish, and an
avoidance of processed red meat (beef, pork,
lamb), animal fats, and refined carbohydrates.
People who consume large amount of
lutein-rich foods such as chicken eggs, spinach,
tomatoes, oranges and leafy greens experienced
the lowest incidence of colon cancer.
SpinachTomatoes
CabbageFish
CONCLUSIONNutraceuticals are currently receiving
recognition as being beneficial in coronary heart
disease, obesity, diabetes, cancer, osteoporosis and other
chronic and degenerative diseases such as Parkinson's
and Alzheimer's diseases. Evidences indicate that the
mechanistic actions of natural compounds involve a
wide array of biological processes, including activation
of antioxidant defences , signal transduction pathways,
cell proliferation and differentiation and preservation of
mitochondrial integrity.
REFERENCES: Brower V. Nutraceuticals: poised for a healthy slice of the
healthcare market? Nat Biotechnol. 199; 16: 728-731.
Eskin N A M and Tamir S Dictionary of Nutraceuticalsand Functional Foods, CRC Press, Boca Raton, USA. 2006.
Rajesekaran A, Sivagnanam G, Xanvier R; Nutraceuticals
as therapeutic agents;2008.
Temple WJ and Gladwin KK. Fruits, vegetables, and the.
Prevention of cancer: Research challenges. Nutrition.
2003; 19: 467-470.
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