NutraceuticalsThe Road Ahead

V. HARIHARANCEO & MANAGING DIRECTOR

PHYTOTECH EXTRACTS PVT. LTD.

BENGALURU

INDIA

Nutraceuticals

“Nutraceutical are defined as “Any substance that is food or part of food that provides Medical and/or Health benefits including prevention and treatment of disease”

Dr. Steve De Felice “Foundation for innovation in Medicine -US in 1989”

Back to Nature

Back to the nature to back our future

Nutraceuticals

Wellness - Nutraceuticals

A healthy balance of the body & mind results in a feeling of well-beingTiredness & stress are common problems today and Nutraceuticals address theseNutraceuticals will help to be good always ! Good means wellness

Pharmaceuticals & Nutraceuticals

Pharma says “Cure first and follow diet next”, the Nutraceuticals says “Follow diet first and cure next”.Switch lifestyle from “Eat & Act” (independently) to “Eat well & Act well” (Dependently) – Choose Nutraceuticals is best for the country and best for the world

Pharmaceuticals & Nutraceuticals

According to a report by Frost & Sullivan, Indian Nutraceuticals market is projected to grow to US $4 billion in 2018 at a compound annual growth rate (CAGR) of 17%Functional foods & beverages constitute 60% of the Indian Nutraceuticals market while rest 40% is dietary supplements

Laws governing

DHSEA – Dietary Health Supplement & Education Act (USA)FSMA – Food Safety Modernisation Act 2011FOSHU- Foods for Special Health Use (Japan)FSSAI - Food Safety Standards Authority of India Codex regulations are on the anvilWHO is working on the guidelines for Nutraceuticals

Issues

Quality , Safety and EfficacyStandardizationActive compound isolationElaborate pharmacological testing & toxicity testingSAR ( Structure Activity Relationship)

Issues

Use of marker compoundsFinger Printing Use of sophisticated equipments – HPTLCStability Testing – Accelerated & Ambient tempExpiry dates

INNOVATIONSProduct and Package

The innovations should take care of Newer concepts built in to the product design focusing stability and safety of the product Product should be delicious and palatable Product should be customer friendly with convenience & compliance Package should be with easy administrationShould be economical and affordable to common man

Focus on R&D

Selecting right Nutraceutical dosage forms.De-bitterizing the extracts and making palatable formulations.Deeper insight of In-vitro & in-Vivo studies of the actives as well as the formulationsConducting stability studies following ICH guidelines and conforming the shelf life of the products Trade dress with consumer friendly packaging Conforming to FSSAI regulations

Newer Products

Switch over from conventional dosage forms such as tablets, capsule and liquids to newer innovative forms :

• Herbal Teas • Instant Energy bars• Ready to Drinks ( RTDs)• Chocolates / Candies • Gummies ( Gelatin ,Pectin or Fruit base )

Newer products ..

• Chewing gums• Chewable capsules • Lozenges• Pastilles• Buccal Films • Sublingual drops• Instant dissolving granules• Biscuits, Cookies and Diskettes • Popsicles and so on…

Aloe & Collagen Drink

Buccal Films

NUTRIGENOMICS

Addresses the role of diet in gene

expression

Nutrigenomics – Future

Development of personalized foods for the future

The DNA diet (Should your genes decide what you like to eat?)

Nutrigenomics – Future

Scientists have identified a few novel Bcl-2 phosphorylating molecules and Cox-II inhibitors from herbal products and functional foods and they are in the process of developing new food products by placing them in the foods

Nutrigenomics – Future

e.g.: CoxII cereals (adding Cox II inhibiting nutraceuticals in cereals), CoxII cookies, CoxII juices, CoxII chocolates, Bcl-2 chocolates, candies, cookies, muffins and soft drinks (anti-Bcl-2 Nutraceuticals). Finally, with the presence of more new nutraceuticals in the pipeline than ever before, the juncture between discovery and the effect on genes and proteins is underway

Formulations

All parts of our body age but you know the tongue never ages. So the taste is the most important for a Nutraceutical productAhara (Food) Anna (Nutrients )Food prepared with love & affection (care) give more nutrients . So too, are the Nutraceutical formulations

THANK YOU