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www.gscn.org of the German Stem Cell Network (GSCN) November 3-5, 2014 German Cancer Research Center (DKFZ) Heidelberg 2 nd Internaonal Annual Conference Conference Program

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of the German Stem Cell Network (GSCN)November 3-5, 2014German Cancer Research Center (DKFZ)Heidelberg

2nd Internati onal Annual Conference

Conference Program

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gscn_programmheft_epp_ad_148x210_2014_08.indd 1 28.08.14 10:59GSCN_Titelseite_Programm_A5_2014 Kopie.indd 1-3 21.10.14 09:28

2nd International Annual Conference of the GSCN November 3 – 5, 2014 I DKFZ Heidelberg, Germany

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Program

MONDAY, November 3rd

11:00–12:00 Registrationandlightlunch

OpeningLecture hall:12:00–12:05 WelcometotheGermanCancerResearchCenter(DKFZ):

Otmar Wiestler(ChairmanandScientificDirector,DKFZ)12:05–12:15 Andreas Trumpp(ActingPresident,GSCN)12:15–12:30 Openingremarks

Bärbel Brumme-Bothe(DepartmentHead“LifeSciences”,BMBF)12:30–13:15 Keynote lecture I

K1-Exploringthehierarchicalorganizationofcolorectalcancer Eduard Batlle;InstituteforResearchinBiomedicineBarcelona,Spain (Chair: Andreas Trumpp) supported by Eppendorf AG

13:15–14:00 Keynote lecture II K2-MyocardialregenerationbyESC-derivedcardiacprogenitors Philippe Menasché;HospitalEuropeanGeorgePompidou,Paris,France (Chair: Ulrich Martin)

14:00–14:30 Coffeebreak / industryexhibition

Concurrent scientific working group session ILecture hall: Stem cells in regenerative therapies I (chair: Ulrich Martin / Hans-Dieter Volk)14:30–14:50 Stemcellsinregenerativetherapies–Introduction

Ulrich Martin;Rebirth / HannoverMedicalSchool14:50–15:05 T01-Intranasaldeliveryofmigratoryneuralstem/progenitorcells:Anon-

invasivepassagetotherapeuticallytargetintracerebralbraintumors Nils Ole Schmidt;UniversityMedicalCenter,Hamburg-Eppendorf

15:05–15:20 T02-MicroRNA-181apromoteshumanneuronaldifferentiationbydown-regulatinggenesinvolvedinneuralstemcellmaintenance Laura Stappert;InstituteofReconstructiveNeurobiology,Bonn

15:20–15:35 T03-Pulmonarytransplantationofmultipotent-orpluripotent-stemcellderivedmacrophagesasanoveltreatmentoptionforpulmonaryalveolarproteinosis Nico Lachmann; Hannover Medical School

15:35–15:50 T04-HumaniPSC-derivedMSC-likeprogenitorcells:functionaldifferencesfromprimaryMSCsaffectingtheiruseincartilageregenerativemedicine Solvig Diederichs;UniversityHospitalHeidelberg

15:50–16:00 Groupdiscussion

Conferenceprogram 15

Room K 1: Stem cells in disease: cancer stem cells (chair: Thomas Brabletz / Andreas Trumpp)14:30–14:50 Conceptsofcancerstemcells–Introduction

Andreas Trumpp;GermanCancerResearchCenter,Heidelberg14:50–15:05 T05-Shp2Signalingisessentialtothesuppressionofsenescenceinmammary

gland cancer stem cells in mice Linxiang Lan;MaxDelbrückCenter,Berlin

15:05–15:20 T06-Humanizationofmousemodelsforhumanbreastcancerusingmesenchymalstemcells Maxine Silvestrov;ExperimentalPharmacology&Oncology(EPO)GmbH,Berlin

15:20–15:35 T07-Targetingthekinometoinducedifferentiationinhumanbreastcancerstem cells Jochen Maurer;UniversityMedicalCenterFreiburg

15:35–15:50 T08-CD151+cellsdrivetumor-initiation,hierarchicalgrowthandproliferation-associatedsignalinginpatient-derivedmodelsofserousovariancancer Franziska Zickgraf;GermanCancerResearchCenter,Heidelberg

15:50–16:00 Groupdiscussion

Room K 2: Computational stem cell biology (chair: Georg Fuellen / Ingo Roeder)14:30–14:45 Computationalstemcellbiology–Overviewandintroduction

Ingo Roeder;DresdenUniversityofTechnology14:45–14:55 T09-Whatmakesstemcellsmove?Studyingstemcellmigrationinvitro

(back-to-backpresentationwithT10) Michael Ansorge;LeipzigUniversity

14:55–15:05 T10-Whatmakesstemcellsmove?Studyingstemcellmigrationinsilico (back-to-backpresentationwithT09) Axel Krinner;DresdenUniversityofTechnology

15:05–15:20 T11-Characterizingtranscriptionalcell-to-cellheterogeneitiesduringstemcelldifferentiation Fabian Theis;HelmholtzCenterMunich

15:20–15:35 T12-Anetwork-basedstrategytodirectcellfatedetermination Antonio del Sol;LuxembourgCenterforSystemsBiomedicine

15:35–15:50 T13-Computationalidentificationofpluripotencynetworks Maryam Nazarieh;SaarlandUniversity,Saarbrücken

15:50–16:00 Groupdiscussion

ZMBH (groundfloor): Somatic stem cells (chair: Thomas Braun / Ana Martin-Villalba)14:30–14:50 Studiesonsomaticstemcells–anintroduction

Thomas Braun;MaxPlanckInst.f.HeartandLungRes.,BadNauheim14:50–15:05 T14-TheRNAhelicaseDDX6regulatescell-fatespecificationinneuralstem

cells via miRNAs Sarah Nicklas;LuxembourgCenterforSystemsBiomedicine

15:05–15:20 T15-AngiogenesiscontrolsneuralstemcellexpansionbyregulatingtissueoxygenationandHIFsignaling Christian Lange; VIBKULeuvenCampus,Belgium

Conferenceprogram

2nd International Annual Conference of the GSCN November 3 – 5, 2014 I DKFZ Heidelberg, Germany

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15:20–15:35 T16-Regulationofasymmetric/symmetricstemcelldivisioninhumanepidermis Katharina Nöske;GermanCancerResearchCenter,Heidelberg

15:35–15:50 T17-Clonalheterogeneitywithintheexocrinepancreas Damian Wollny;GermanCancerResearchCenter,Heidelberg

15:50–16:00 Groupdiscussion

16:00–16:15 Coffeebreak / industryexhibition

16:15 – 18:15 Poster session I: P001 – P097 supported by Fluidigm Europe B�V� (posterswillbedisplayedinthetent) P001–P017:Pluripotencyandembryonicstemcells P018–P038:Programingandreprograming P039–P061:Stemcellsindevelopment P062–P072:Somaticstemcells (posterswillbedisplayedinfrontofroomK1+2) P073–P097:Hematopoieticstemcells

Evennumbers:pleasepresentyourposterfrom16:15–17:15 Unevennumbers:17:15–18:15

18:15–19:15 Dinner

Lecture hall:19:15–20:45 GSCNGeneralMembershipMeeting20:45–21:30 Get-together

Conferenceprogram 17

TUESDAY, November 4th

Concurrent scientific working group session IILecture hall: Stem cells in disease modeling and drug development

(chair: Oliver Brüstle / Karl-Ludwig Laugwitz) supported by Lonza Cologne GmbH

09:00–09:20 Theuseofstemcellsindiseasemodelinganddrugdevelopment–Overview Oliver Brüstle;InstituteofReconstructiveNeurobiology,Bonn

09:20–09:35 T18-ProbingmitochondrialDNAdisordersusingiPSC-derivedneuralprogenitors Alessandro Prigione; MaxDelbrückCenter,Berlin

09:35–09:50 T19-ModelingDravetsyndromeiniPScell-derivedneurons Matthias Hebisch;InstituteofReconstructiveNeurobiology,Bonn

09:50–10:05 T20-Thefunctionalityofstemcellderivedneurons:Howtodefineit? Sebastian Illes; Inst.ofMolecularReg.Medicine,Salzburg,Austria

10:05–10:20 T21-Modelingandpharmacologicalrescueofionchanneldiseasesenabledbyimprovedcardiacinductionofhumanpluripotentstemcellsin2Dand3Dformats Boris Greber;MaxPlankInstituteforMolecularBiomedicine,Münster

10:20–10:30 Groupdiscussion

Room K 1+2: Pluripotency and embryonic stem cells (chair: James Adjaye / Mathias Treier)09:00–09:20 Pluripotencyandembryonicstemcells:Introductionandoverview

James Adjaye; UniversityHospitalofDüsseldorf09:20–09:35 T22-Primate-specificendogenousretrovirusdriventranscriptiondefines

naïve-like stem cells Jichang Wang;MaxDelbrückCenter,Berlin

09:35–09:50 T23-AnovellncRNA-proteininteractioncharacterizesmouseembryonicstemcell fate Debojyoti Chakraborty;DresdenUniversityofTechnology

09:50–10:05 T24-NANOGandCDX2patterndistinctsubtypesofhumanmesodermduringexitfrompluripotency Sasha Mendjan;CambridgeStemCellInstitute,UnitedKingdom

10:05–10:20 T25-Insightsfromthestreak:identificationofnovelgenesassociatedwithgerm-layerformationandmesendodermdifferentiation Cantas Alev;RIKENCenterforDevelopmentalBiology,Kobe,Japan

10:20–10:30 Groupdiscussion

ZMBH(groundfloor): Stem cells in development (chair: Jan Lohmann / Francesca Spagnoli)09:00–09:15 Stemcellsindevelopment–Overview

Jan Lohmann; Centre for Organismal Studies Heidelberg 09:15–09:30 T26-Tet-dependentprocessingof5-methylcytosineprotectsDNAmethylation

canyonsagainsthypermethylation Achim Breiling;GermanCancerResearchCenter,Heidelberg

Conferenceprogram

2nd International Annual Conference of the GSCN November 3 – 5, 2014 I DKFZ Heidelberg, Germany

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09:30–09:45 T27-PIEZO2isrequiredformechanotransductioninhumanES-cell-derivedtouchreceptors Katrin Schrenk-Siemens;UniversityofHeidelberg

09:45–10:00 T28-Transcriptionalandepigeneticdynamicsunderlyingcelllineagecommitment Filippo M. Cernilogar;LudwigMaximilianUniversity,Munich

10:00–10:15 T29-Thehistone3lysine4methyltransferaseMll2primestheNxt2promoterforneuraldifferentiation Katrin Neumann;DresdenUniversityofTechnology

10:15–10:30 T30-Signalsfromtheinjurynicheincreasefatepotentialofadultneuralstemcells Enric Llorens Bobadilla;GermanCancerResearchCenter,Heidelberg

10:30–11:15 Coffeebreak / industryexhibition

Industry session: “Technologies from GSCN industry partners”Lecture hall: Main supporters11:15–11:20 Introduction(Andreas Trumpp)11:20–11:50 C01-HighthroughputscreeningusingiPSC-basedmodels

Jared Sterneckert;CRTDresden,representingPeproTechGmbH11:50–12:20 C02-Controllingexpansionandcardiomyogenicdifferentiationofhuman

pluripotentstemcellsinscalablesuspensionculture Robert Zweigerdt;MHHannover,representingEppendorfAG

12:20–12:50 C03-Rawmaterialsinthemanufactureofadvancedtherapiesmedicinal products:Qualityattributesandqualityassurance Bernd Leistler; CellGenix GmbH

Room K 1+2: Supporters11:15–11:20 Introduction(Michael Cross)11:20–11:50 C04–EfficientneuralandcardiacdifferentiationsystemsforiPSC

Mohan C. Vemuri;LifeTechnologiesGmbH11:50–12:20 C05-Cell-basedgenedeliveryleveragesconventionalimmunotherapyfor

cancer;TreatmentofadvancedgastrointestinalcancerinaphaseI/IItrialwithmodifiedautologousMSC_apceth_101 Volker Scherhammer;apcethGmbH&Co.KG

12:20–12:50 C06-Scalableenzyme-freeprotocolsfortheisolationandmaintenanceof humaninducedpluripotentstemcellswithoutmechanicalcolonyscraping Alexandra Blak;STEMCELLTechnologiesSARL

ZMBH(groundfloor): Supporters11:15–11:20 Introduction(Torsten Tonn)11:20–11:50 C07-Thefutureiscounting–DigitalanalysisofRNA,DNAandproteinbiomarkers

Maik Pruess;NanoStringTechnologiesGermanyGmbH11:50–12:20 C08–PrimateiPScellsastoolsforevolutionaryanalyses

Wolfgang Enard;LudwigMaximilliansUniversity,Munich;representing FluidigmEuropeB.V.

Conferenceprogram 19

12:20–12:50 C09–Buildingbridgesfromresearchtotherapy:Aroadmapforthesuccessfulgenerationofclinical-gradeiPSCs Thomas Fellner;LonzaCologneGmbH

12:50–14:30 Lunchbuffet / industryexhibition / posterviewing supported by STEMCELL Technologies SARL

13:15–14:15 Room K 1+2: Explainingscienceandmotivatingpeople–Outreachmaterialsfor stem cell research (Tobias Cantz / Ira Herrmann)

Concurrent strategic working group session ALecture hall: Career development (chairs: Hartmut Geiger / Insa Schröder)14:30–14:45 Careersinindustry, Andreas Bosio; MiltenyiGmbH,Berg.Gladbach14:45–15:00 Careersinscienceadministration,Hella Lichtenberg; DLRBonn15:00–15:15 Careersinacademia,Hartmut Geiger / Insa Schröder15:15–15:30 Paneldiscussion

Room K 1+2: Clinical trials and regulatory affairs I (chair: Andreas Kurtz / Torsten Tonn / Hans-Dieter Volk) supported by apceth GmbH & Co� KG

14:30–14:50 DevelopmentofiPScell-basedcardiactherapy Ulrich Martin, MH Hannover

14:50–15:10 Regulatorychallengesofstemcell-basedmedicinalproducts Egbert Flory;PaulEhrlichInstitute,Langen

15:10–15:30 Groupdiscussion

ZMBH(groundfloor): Large scale banking of human pluripotent stem cells – workshop (chair: Andreas Kurtz / Joana Namorado)

14:30–14:45 BiomedicalapplicationsofiPScelltechnology Angel Raya; CMRB Barcelona

14:45–15:00 Theneedforlarge-scaleiPSCcollections-apharmaperspective Alex Gutteridge;Pfizer

15:00–15:15 Deliveryofhumanpluripotentstemcellsfortherapy:PhaseIVoftheUKStemCellBankProject Lyn Healy;UKStemCellBank,SouthMimms,U.K.

15:15–15:30 Therelaunchofthehumanpluripotentstemcellregistry(hESCreg) Andreas Kurtz;BCRTBerlin

15:30–15:45 Shortbreak

Concurrent strategic working group session BLecture hall: Stem cell technologies (chair: Andreas Bosio / Frank Emmrich)15:45–15:50 Introduction:Andreas Bosio,MiltenyiGmbH,Berg.Gladbach15:50–16:05 Methodsofgeneticengineering

Claudio Mussolino; UniversityofFreiburg

Conferenceprogram

2nd International Annual Conference of the GSCN November 3 – 5, 2014 I DKFZ Heidelberg, Germany

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16:05–16:20 Reprogrammingtechnologies Micha Drukker;HelmholtzCenterMunich

16:20–16:35 Methodsoflasercellprinting Boris Chichkov; LaserCenterHannover(LZH)

16:35–16:45 Groupdiscussion

Room K 1+2: Clinical trials and regulatory affairs II (chair: Andreas Kurtz / Torsten Tonn / Hans-Dieter Volk)

15:45–16:05 Placentaexpandedmesenchymal(PLX)cells–preclinicaldataforpreparingclinical trials Lena Pinzur;PluriStemTherapeuticsInc.,Haifa,Israel

16:05–16:25 PLXcells–frompreclinicaltoclinicalstudies–whatdidwelearnsofarfrombiomarkerstudies? Hans-Dieter Volk;Berlin-BrandenburgCenterforReg.Therapies(BCRT)

16:25–16:45 Paneldiscussions

ZMBH(groundfloor): Funding opportunities for young and advanced scientists (chair: Hartmut Geiger / Albrecht Müller)

15:45–16:30 FundingopportunitiesoftheDFGforstemcellscientistsatvariouscareerstages Eckard Picht;GermanResearchFoundation(DFG),Bonn

16:30–16:45 Groupdiscussion

16:45–17:15 Coffeebreak / industryexhibition

16:45–17:45 DKFZ Mensa:Meet-the-experttable:Stem cell technologies – genetic engineering (Claudio Mussolino) limited to 10 registered participants

17:15–19:15 Poster session II: P098 – P187 (posterswillbedisplayedinthetent) P098–P129:Stemcellsinregenerativetherapies P130–P161:Stemcellsindiseasemodelinganddrugdevelopment (posterswillbedisplayedinfrontofroomK1+2) P162–P178:Stemcellsindisease:Cancerstemcells P179–P187:Computationalstemcellbiology

Evennumbers:pleasepresentyourposterfrom17:15–18:15 Unevennumbers:18:15–19:15

19:15–20:00 FreebusshuttletoNetworkingEvening (busseswilldepartfromtheDKFZmainentrance)

20:00–01:00 NetworkingEveningwithdinnerbuffetatSchlosshotel“Molkenkur” Klingenteichstr.31,69117Heidelberg(www.molkenkur.de) (Opening:Oliver Brüstle)(includedintheregistrationfee) supported by CellGenix GmbH

Conferenceprogram 21

WEDNESDAY, November 5th

Concurrent scientific working group session IIILecture hall: Hematopoietic stem cells (chair: Anthony Ho / Claudia Waskow)09:00–09:20 Introduction“Hematopoieticstemcells”

Claudia Waskow;TechnicalUniversityDresden09:20–09:35 T31-Stroma-derivedosteopontinregulateshematopoieticstemand

progenitorcellsfunctionuponaging Novella Guidi;UniversityofUlm

09:35–09:50 T32-IdentificationofregulatorynetworksinHSCsandtheirimmediate progenyviaintegratedproteome,transcriptome,andDNAmethylomeanalysis Daniel Klimmeck;GermanCancerResearchCenter,Heidelberg

09:50–10:05 T33-Kitdeficiencyregulatesstablehumanhematopoieticstemcell engraftmentinmice Susann Rahmig;TechnicalUniversityDresden

10:05–10:20 T34-STAT5-regulatedmiRNA193bcontrolshematopoieticstemandprogenitorcellexpansionbyfinetuningcytokinesignaling Nadine Hätscher;UniversityHospitalFrankfurt

10:20–10:30 Groupdiscussion

Room K 1+2: Programming and reprogramming (chair: Micha Drukker / Frank Edenhofer)09:00–09:15 Introductiontore-programming

Frank Edenhofer;UniversityofWürzburg09:15–09:30 T35-SelectivegenedeliveryintohumaniPScellsbasedonCD30-targeted

lentiviralvectors Thorsten Friedel;PaulEhrlichInstitute,Langen

09:30–09:45 T36-GenerationofiPScellsfromyoungvs.agedcellsources–influenceofdonorageonreprogrammingefficiencyandgeneticstabilityofiPSclones Katarzyna Osetek;LEBAO / HannoverMedicalSchool

09:45–10:00 T37-MesenchymalstemcellsderivedfromiPScellsfromagedindividuals acquirefetalcharacteristics Lucas Spitzhorn; UniversityHospitalofDüsseldorf

10:00–10:15 T38-TRIM32,adualplayerregulatingtheentryandexitfrompluripotency Lamia’a Bahnassawy;UniversityofLuxembourg

10:15–10:30 T39-RobustgenerationofcardiomyocytesfromhumaniPScellsrequires precisemodulationofBmpandWntsignaling Asifiqbal Kadari;JuliusMaximiliansUniversity,Würzburg

DKFZ SR 4th floor: Stem cells in regenerative therapies II (chair: Michael Cross / Frank Emmrich)H2.04.073

The meeting point for this session is at the registration desk!09:00–09:15 IntroductiontosessionIIstemcellsinregenerativetherapies

Michael Cross;UniversityofLeipzig

Conferenceprogram

2nd International Annual Conference of the GSCN November 3 – 5, 2014 I DKFZ Heidelberg, Germany

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09:15–09:30 T40-EfficientgenerationoffunctionallydefinediPSC-derivedhumanneuralstem/progenitorcellsandoligodendrocytes Giacomo Frati;SanRaffaeleScientificInstitute,Milan,Italy

09:30–09:45 T41-Agingaffectsthemesenchymalstemcellderivedoligodendrogenic /  remyelinationactivities:implicationforapotentialtherapyofmultiplesclerosis Francisco J. Rivera;ParacelsusMedicalUniversity,Salzburg,Austria

09:45–10:00 T42-TheeuropeanprojectREBORNE:Multipotentmesenchymalstromalcellsand biomaterial for bone healing Alexander Erle;UlmUniversityHospital

10:00–10:15 T43-Identification,isolationandtargetedinhibitionofafibroblastlineageresponsibleforscarringandcancerstroma Yuval Rinkevich;StanfordInstituteforStemCellBiologyandRegenerativeMedicine,U.S.A.

10:15–10:30 T44-Proofingthe(Un)Proven:Provenorapprovedstemcelltherapies– thatisthequestion Bianca Büchner;CenterforEthicsandLawintheLifeSciences(CELLS),Hannover

10:30–11:00 Coffeebreak / industryexhibition

Concurrent workshopsLecture hall: Clinical relevance of animal models in stem cell research and regenerative

medicine (chair: Georg Duda / Frank Emmrich) (Workshopofthe‘RegenerativeMedicineInitiativeGermany(RMIG)’)

11:00–11:20 Introduction:Animalmodelsinresearchforregenerativemedicine Axel Haverich;Rebirth / HannoverMedicalSchool

11:20–11:30 Celltransplantationintopre-clinicalmodelsofretinaldegeneration Marius Ader; CenterforRegenerativeTherapiesDresden

11:30–11:40 Medicaldevicesandtheapplicationofstemcells Konrad Kohler;zrm,TübingenUniversityHospital

11:40–11:50 Regenerativemedicineforanagingsociety:Howrelevantareourcurrent animalmodels? Georg Duda;BCRTBerlin

11:50–12:00 Heterogeneity,age,comorbiditiesandthetranslationalfailure–canwedobetterinprojectingfrompreclinicalstemcellstudiestoclinicaltrials? Johannes Boltze;TRMLeipzig

12:00–12:10 Hurdlesforclinicaltranslationofregenerativestemcelltherapy– lessonslearnedfromthecardiacPhaseIIIPERFECTmulticentertrial Gustav Steinhoff;RTCRostock

12:10–12:30 Paneldiscussion

Room K 1+2: Big pharma and the stem cell field – matching expectations? (organizer:Oliver Brüstle / Ira Herrmann) (WorkshopoftheStemCellNetworkNorthRhineWestphalia)

Conferenceprogram 23

Panel: Oliver Brüstle;LIFE&BRAINGmbH,Bonn Ralf Heilker; BoehringerIngelheimPharmaGmbH&Co.KG,Div.ResearchGermany Jörg Hüser;BayerPharmaAG,LeadDiscoveryWuppertal Bert Klebl;LeadDiscoveryCenterGmbH,Dortmund Moderation:Ira Herrmann;StemCellNetworkNRW,Düsseldorf

ZMBH(groundfloor): Proceedings of the German Society for Stem Cell Research (GSZ e.V.) (chair: Jürgen Hescheler)

11:00–11:10 Introduction11:10–11:30 Sinusnodalcellsfrompluripotentstemcells

Robert David;ReferenceandTranslationCenterforCardiacStemCell Therapy(RTC),Rostock

11:30–11:50 Chondrogeniclineagedeterminationduringdifferentiationofmouseembryonicstem cells Jürgen Rohwedel;UniversityofLübeck

11:50–12:10 UseoftranscriptomicsandepigeneticapproachesinhumanESC-based developmentalneurotoxicology(DNT)testing Tanja Waldmann;UniversityofKonstanz

12:10–12:30 LongtermcultureofiPSC-derivedcardiomyocytesonmechanically-definedsubstrates Carlos Heras;UniversityofCologne

12:30–12:45 Shortbreak

Lecture hall:12:45–13:30 Keynote lecture III

K3-Molecularandcellularregulationofmusclestemcellsduringdevelopmentandregeneration Shahragim Tajbakhsh;InstitutePasteur,Paris,France (Chair: Oliver Brüstle)

13:30–15:00 Lunchbuffet / industryexhibition supported by Nanostring Technologies Germany GmbH

13:45–14:45 Room K 1+2:Explainingscienceandmotivatingpeople–Outreachmaterialsforstem cell research (Tobias Cantz / Ira Herrmann)

13:45–14:45 DKFZ Mensa:Meet-the-experttable:Stem cell technologies – laser printing (Boris Chichkov)and– reprogramming technologies (Micha Drukker) limited to 10 registered participants each

Closing ceremonyLecture hall:15:00–15:15 Posterawardceremoniesandannouncementofindustryquizwinners

(Daniel Besser; GSCN) supported by PeproTech GmbH

15:15–15:30 Outlookandclosingremarks Incomingpresident:Thomas Braun

Conferenceprogram

2nd International Annual Conference of the GSCN

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15:30–16:15 Keynote lecture IV – Joined session with the 6th BMBF symposium – Adult neural stem cells (Chair: Magdalena Götz / Ana Martin-Villalba) K4-Modelinghumanbraindevelopmentanddiseasein3Dculture Jürgen Knoblich;InstituteofMolecularBiotechnology(IMBA) Vienna,Austria supported by Life Technologies GmbH

16:15–17:00 K5-Adulthippocampalneurogenesis:Whatarenewneuronsgoodfor? Andwhatisgoodforthem? Amelia Eisch;UTSouthwestern,Dallas,U.S.A.

17:00–17:45 K6-Amechanismforthesegregationofageinmammalianneuralstemcells Sebastian Jessberger; UniversityofZurich,Switzerland

End of GSCN conference

Announcements:18:30–20:00 PublicoutreacheventoftheGSCNincollaborationwiththeScheringStiftung

andtheDKFZ(inGerman) Stammzellen als Chance – Realität und Perspektiven PodiumsdiskussionzuraktuellenForschunginLaborundKlinik

Panel: Magdalena Götz(LMUMünchen),Anthony Ho(Uni.Heidelberg), Andreas Trumpp(DKFZ) Moderation:Stefanie Seltmann(DKFZ)

20:00–21:00 Receptionpublicoutreachevent

and

November 6th, 2014 – GSCN Satellite Event: 6th BMBF Symposium – Adult neural stem cellsTheprogramofthesatelliteeventisavailableatthereceptiondesk.

Supported by:

Conferenceprogram