on the mend. - science · 2016-12-05 ·...

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On the mend. NEW ENGLAND BIOLABS ® , NEB ® and NEBNext ® are registered trademarks of New England Biolabs, Inc. BIOANALYZER ® is a registered trademark of Agilent Technologies, Inc. While archiving of clinical materials as Formalin-Fixed, Paraffin-Embedded (FFPE) samples is common, it causes significant damage to the sample’s DNA. As a result, such samples can be difficult to sequence. The cocktail of enzymes in the NEBNext FFPE DNA Repair Mix repairs multiple types of damage that are common among FFPE samples, thereby improving yields and overall library success rates. Make sure your sample’s DNA is on the mend before your next sequencing experiment! NEBNext ® FFPE DNA Repair Mix from New England Biolabs ® Visit www.neb.com/M6630 to learn more. An example of Agilent Bioanalyzer ® traces of libraries prepared from stomach tumor FFPE DNA that was treated with the FFPE DNA Repair Mix, or was untreated, before library construction. Yield improvements of 101% to 458% have been observed. Effect of FFPE DNA Repair Mix on library yields FFPE DNA Repair + FFPE DNA Repair

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On the mend.

NEW ENGLAND BIOLABS®, NEB® and NEBNext® are registered trademarks of New England Biolabs, Inc.

BIOANALYZER® is a registered trademark of Agilent Technologies, Inc.

While archiving of clinical materials as

Formalin-Fixed, Paraffin-Embedded (FFPE)

samples is common, it causes significant damage

to the sample’s DNA. As a result, such samples

can be difficult to sequence. The cocktail of

enzymes in the NEBNext FFPE DNA Repair Mix

repairs multiple types of damage that are common

among FFPE samples, thereby improving yields

and overall library success rates.

Make sure your sample’s DNA is on the mend

before your next sequencing experiment!

NEBNext® FFPE DNA Repair Mix

from New England Biolabs®

Visit www.neb.com/M6630 to learn more.

An example of Agilent Bioanalyzer® traces of libraries prepared from stomach

tumor FFPE DNA that was treated with the FFPE DNA Repair Mix, or was

untreated, before library construction. Yield improvements of 101% to 458%

have been observed.

Effect of FFPE DNA Repair Mix on library yields

– FFPE DNA Repair

+ FFPE DNA Repair

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registered trademarks of Eppendorf AG, Germany. U.S. Design Patents are listed on www.eppendorf.com/ip

ODers may vary by country. All rights reserved, including graphics and images. Copyright © 2015 by Eppendorf AG.

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