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Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

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Page 1: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

Donor Identification and Referral Jeremy BrownHuw Twamley4th June 2013

1

LONDON

Page 2: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

Regional Data

2

Jeremy Brown

LONDON

Page 3: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

-------- National rate

95 9788

9398

86 8791

95

8489 89

Ref

erra

l rat

e (%

)

0

20

40

60

80

100

Team

Easte

rn

London

Mid

lands

North

Wes

t

Norther

n

Norther

n

Irela

nd

Scotla

nd

South

Centra

lSouth

East

South

Wal

es South

Wes

t

York

shire

DBD referral rate

1 April 2012 to 31 March 2013, data as at 4 April 2013

2nd

Organ Donation Past, Present and Future 3

LONDON

Page 4: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

Ref

erra

l rat

e (%

)

0

20

40

60

80

100

Number of neurological death suspected patients

0 10 20 30 40 50 60

110

111213

14

1516 171819 22021 2223 24

2526

27

28

29

330 45

6

7

8

9

Hospital National rate 95% Lower CL95% Upper CL 99.8% Lower CL 99.8% Upper CL

London DBD referral rate

1 April 2012 to 31 March 2013, data as at 4 April 2013

Organ Donation Past, Present and Future 4

Page 5: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

-------- National rate

80

72

54

72

81

52

42

54 5659 60

65

Ref

erra

l ra

te (

%)

0

20

40

60

80

100

Team

Easte

rn

London

Mid

lands

North

Wes

t

Norther

n

Norther

n

Irela

nd

Scotla

nd

South

Centra

lSouth

East

South

Wal

es South

Wes

t

Yorksh

ire

1 April 2012 to 31 March 2013, data as at 4 April 2013

Organ Donation Past, Present and Future 5

Tied 3rd

DCD referral rateLONDON

Page 6: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

London DCD referral rate

Organ Donation Past, Present and Future 6

Ref

erra

l rat

e (%

)

0

20

40

60

80

100

Number of imminent death anticipated patients

0 10 20 30 40 50 60 70 80

1

1011

12

13

14

15

16

17

18

19

220 2122

23

24

25 26

27

28

29

3

30

45

6

7

8

9

Hospital National rate 95% Lower CL95% Upper CL 99.8% Lower CL 99.8% Upper CL

Page 7: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

Identification and Referral

7

Dr Huw TwamleyNorth West Regional CLOD

Page 8: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Timely Identification and Referral of Potential Organ Donors

Organ Donation Past, Present and Future

www.odt.nhs.uk

Page 9: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

LONDON

Organ Donation Past, Present and Future

Session Objectives

9Organ Donation Past, Present and Future

• Understand difficulties with donor identification and referral

• Recognise benefits of improving elements of the process

– Increased identification and referral

– Timely referral

– Responsiveness to referral

• Consider which of the proposed methods of identification and referral may work in your hospital

Page 10: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

UK rates of referral

referral of deceased donors

0

20

40

60

80

100

2005-6 2006-7 2007-8 2008-9 2009-10 2010-11 2011-12

year

pe

rce

nta

ge

DBD DCD

Organ Donation Past, Present and Future

91%

52%

Page 11: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

Overall timings

Organ Donation Past, Present and Future

Page 12: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

Potential donor

• 83 year old• OOH PEA cardiac arrest• Downtime 15-20 minutes• Known hypertensive ( three anti-

hypertensives)• Benign Prostate Hyperplasia

Organ Donation, Past, Present and Future

Page 13: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

Best Interests

• Recipient• Potential Donor Family• Potential Donor

Page 14: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Aims of Strategy

• 100% Identification of potential Donors

• 100% Referral of Potential Donors

• 100% Timely Referral

• Implement NICE Guidance

The consideration of donation should be core ICU / ED and part of all end of life care plans.

Timely referral promotes this possibility

Organ Donation Past, Present and Future

Page 15: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Ref

erra

l rat

e (%

)

0

20

40

60

80

100

Number of neurological death suspected patients

0 10 20 30 40 50 60

110

111213

14

1516 171819 22021 2223 24

2526

27

28

29

330 45

6

7

8

9

Hospital National rate 95% Lower CL95% Upper CL 99.8% Lower CL 99.8% Upper CL

London DBD referral rate

1 April 2012 to 31 March 2013, data as at 4 April 2013

Organ Donation Past, Present and Future 15

Page 16: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

London DCD referral rate

Organ Donation Past, Present and Future 16

Ref

erra

l rat

e (%

)

0

20

40

60

80

100

Number of imminent death anticipated patients

0 10 20 30 40 50 60 70 80

1

1011

12

13

14

15

16

17

18

19

220 2122

23

24

25 26

27

28

29

3

30

45

6

7

8

9

Hospital National rate 95% Lower CL95% Upper CL 99.8% Lower CL 99.8% Upper CL

Page 17: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

NICE Guideline 135

Organ Donation Past, Present and Future

Page 18: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

British Medical Association 2012

The research data -------- showed that the use of clinical triggers and a requirement to refer according to standard criteria led to an increase in both referrals and donors. It is hoped that implementation of the NICE guideline will result in early and consistent donor referral.

Organ Donation Past, Present and Future

Page 19: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

General Medical Council 2010

I”f a patient is close to death and their views cannot be determined, you should be prepared to explore with those close to them whether they had expressed any views about organ or tissue donation, if donation is likely to be a possibility.”

“You should follow any national procedures for identifying potential organ donors and, in appropriate cases, for notifying the local transplant coordinator.”

Decisions to limit or withdraw treatments in potential DCD donors MUST be in compliance with national End of Life Care policy.

Organ Donation Past, Present and Future

Page 20: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

UK Donation Ethics Committee

“There is no ethical dilemma if the treating clinician wishes to

make contact with the SN-OD at an early stage, while the

patient is seriously ill and death is likely, but before a formal

decision has been made to withdraw life-sustaining

treatment.”

[“Benefits] include establishing whether there are contra-

indications for organ donation……

Other practical and organisational factors might be relevant –

if the SN-OD is based at a distant location then early contact

can help to minimise distressing delays for the family.”

Organ Donation Past, Present and Future

Page 21: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Objectives, benefits and outcomesAll potential donors are identified and referred

All donors are referred in a timely fashion

SN-ODs are deployed in a way that improves responsiveness

All patients are given the option of donation

Access to clinical advicePrompt donor optimisationResolution of potential legal obstaclesEarly assessment of marginal donorsEarly tissue typing / screeningPlanning the family approach

Reduction in delays for families and units

Increased donor numbersImproved consent / authorisation ratesIncrease in donor organsBetter experience for families and staff

Organ Donation Past, Present and Future

Page 22: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

NHSBT Strategy

• Implementation not publication• Key area for collaboration

between hospitals and donor care teams

• Very clear emphasis on benefits– How not who

• Suite of options• Clarity over implementation

Organ Donation Past, Present and Future

Page 23: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Strategy proposals

• Every hospital should have a written policy for the identification and timely referral of all potential donors

• Every donating area within a given hospital adopts a consistent approach

• As far as possible ‘decouple’ early referral from individual clinician

Donation Committees and SN-OD teams should collaborate to develop and implement a policy that ensures that all potential donors are identified and referred in a timely fashion.

Organ Donation Past, Present and Future

Page 24: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

1. Daily visit by SN-OD

Organ Donation Past, Present and Future

Page 25: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

2. Early daily phone call

Organ Donation Past, Present and Future

Page 26: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

3. Daily ICU team safety brief

Organ Donation Past, Present and Future

Page 27: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future

North Bristol Trust ICU Safety Brief

Page 28: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

4. Standard Operating Procedure

Organ Donation Past, Present and Future

Page 29: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Midlands Standard Operating Procedure

Organ Donation Past, Present and Future

Page 30: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

5. Nurse led referrals

Organ Donation Past, Present and Future

Page 31: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Summary

31Organ Donation Past, Present and Future

• Donation should be a element of end of life care

• Make identification and referral routine business of the unit.

• This decouples early referral from the individual clinician caring for the patient

• Implement or develop a solutions /policy for your individual hospitals adopt to timely referral

• Ensure consistency within a given hospital

Page 32: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

Organ Donation Past, Present and Future 32

April - Septem-ber 2010

October 2010 - March 2011

April - Septem-ber 2011

October 2011 - March 2012

April - Septem-ber 2012

October 2012 - March 2013

Num-ber of audited refer-rals

2184 2577 2664 3113 3389 3600

Num-ber of actual DBD and DCD donors from eligible DBD donors

302 330 332 328 329 386

Num-ber of actual DCD donors from eligible DCD donors

168 192 192 228 243 248

250

750

1250

1750

2250

2750

3250

3750

Number of audited referrals and actual donors reported through the Referral Record, data as at 9 May 2013

Nu

mb

er

of

pati

en

ts

Page 33: Organ Donation Past, Present and Future Donor Identification and Referral Jeremy Brown Huw Twamley 4 th June 2013 1 LONDON

What are the barriers to implementing the NICE guidelines in your unit: any solutions?

Organ Donation Past, Present and Future 33

Whichever is the earlier, either:

Use trigger factors in patients with a catastrophic brain injury The absence of one or more cranial nerve reflexes

AND a GCS of 4 or less that is not explained by sedation

And / or a decision is made to perform brainstem death tests.

The intention to withdraw life-sustaining treatment in patients with a life-threatening or life-limiting condition which will, or is expected to, result in circulatory death.