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Technology Transfer Activity Overview of JST's Technology T f A ti iti & N T ransfer Activities & New Funding Program, "A -STEP" Funding Program, A STEP September 15 th , 2009 Miho OKISHIRO Department of Industry-Academic Collaboration Japan Science and Technology Agency

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Page 1: Overview of JST's Technology N &i t i i t ATfT ransfer ... · 11:30- Linking mechanism of research results to Support ... Outline INTRO/Overview 0.Outline Overview of JS T’s Technology

Technology Transfer Activity ①

Overview of JST's Technology T f A ti iti & N Transfer Activities & New Funding Program, "A-STEP"Funding Program, A STEP

September 15th, 2009

Miho OKISHIRO

Department of Industry-Academic Collaboration

Japan Science and Technology Agency

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Program: Tech Transfer Activities

C titi F di P

Program: Tech Transfer Activities10:00- Overview of JST's Technology Transfer Activities

Competitive Funding Programs

10:10- □ New Technology transfer Program “A-STEP" Bottom-up

10:20- □ Strategic Promotion of Innovative Research Top-down10:20 □ Strategic Promotion of Innovative Research and Development

Top down

10:35- □ Comprehensive Support Programs for Creation of Regional Innovation

RegionalCreation of Regional Innovation

10:50- Q&A(1)

Intellectual Property & Various supportsIntellectual Property & Various supports

11:00- □ The Circumstances of IP surrounding Japanese Universities and Our Mission

IP

11:15- □ Strategic support for acquisition and licensing of IPR

IP

11:30- □ Linking mechanism of research results to Supportgpractical application

pp

11:45- Q&A(2)

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OutlineINTRO/Overview 0.Outline

Outline

Overview of JST’s Technology Transfer Activities

1. Mission2. Programs: Two Approaches3 Timeline of Tech Transfer History3. Timeline of Tech Transfer History4. Remarkable Outputs

3

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MissionINTRO/Overview 1.Mission

:To bridge the gaps in R&D pipelineMissionJST advances returning of research

:To bridge the gaps in R&D pipelineg

results generated at universities to the society and nation. y

BasicR h

AppliedResearch/

Scale-up/Commercial

Research/

Development Operation

River of Magic

4Valley of Death

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INTRO/Overview 1.Mission

New Energy and Industrial Technology Development

5

Referred from Mr. Furukawa’s presentation (Sep. 14th)

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INTRO/Overview

Two

2.Programs

1.COMPETITIVE FUNDINGApproaches 【BOTTOM-UP】

A-STEPNew

ACADEMIA【TOP-DOWN】

Strategic Promotion of Innovative New

Universities

Research and Development

【REGIONAL】Comprehensive Support Programs for Partly New

2 Tech Transfer Support

Public Research Institutes

BUSINESS

START-UP

Comprehensive Support Programs for Creation of Regional Innovation

2.Tech Transfer SupportLinking mechanism of research resultsto practical application

TLOs

JST

Center for Intellectual Property Strategies

NEW

PRIVATECOMPANY

6Strategy PlanningCOMPANY

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Increasing Collaborative R&D2.ProgramsINTRO/Overview

Increasing Collaborative R&DCollaborative research continue to increase in number and expenditures.

20,000 500

Collaborative R&D at Universities

15,000

ts

400

R&D expenditures Number of

10,000

# o

f pr

ojec

t

200

300 R&D expenditures acquired from

external sources [$ million]

Number of projects

5,000100

TOTAL 80%

7

02003 2004 2005 2006 2007 2008

0company80%

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Timeline of Tech Transfer HistoryINTRO/Overview 3. Timeline of Tech Transfer History

Timeline of Tech Transfer History1950 1960 1970 1980 1990 2000 2010 2020★

Since 1958JST1950 1960 1970 1980 1990 2000 2010 2020★

funding program

Economy1950 1960 1970 1980 1990 2000 2010 2020

Licensing program etc.

economicrecovery

economicgrowth

trade conflicts

bubble economy

lostdecade

sustainable growth

1950 1960 1970 1980 1990 2000 2010 2020

groundbreakingyears

f i h l i l

independentcreative technology

globalization collaborative science

8

foreign technologicalintroduction Revolutionary era

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Timeline of Tech Transfer HistoryINTRO/Overview 3. Timeline of Tech Transfer History

Timeline of Tech Transfer History1950 1960 1970 1980 1990 2000 2010 2020★

Since 1958JST1950 1960 1970 1980 1990 2000 2010 2020★

funding programuniversity-i d t

emphasis on industrycollaboration

emphasis on intellectual property

Economy1950 1960 1970 1980 1990 2000 2010 2020

Licensing program etc.

University’s restructuringeconomicrecovery

economicgrowth

trade conflicts

bubble economy

lostdecade

sustainable growth

1950 1960 1970 1980 1990 2000 2010 2020

▼Japanese Bayh-Dole Act (1995)

▼The Basic Law on Science and Technology

University s restructuring

groundbreakingyears

f i h l i l

independentcreative technology

globalization collaborative science

▼Japanese Bayh Dole Act

▼Council for Science and Technology Policy(1999)

(2001)▼Japan's national universities became

i d d t ti l ti(2004)

9

foreign technologicalintroduction Revolutionary era

independent national corporations(2004)

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Remarkable Outputs4.Remarkable OutputsINTRO/Overview

Remarkable OutputsManufacturing technology of biocompatible MPC polymer

MPC Polymer

Medical Device

Application

h d h bi difi ti

Coating Materials(e.x. artificial heart)

PC

Cosmetics coating

hydrophobic modification

Contact Lens

SUCCESS in acquiring a new market

PC

Cosmetics MaterialsINVENTORS :

●Nobuo NAKABAYASHI(Tokyo Medical and Dental University)

●Kazuhiko ISHIHARA

Contact Lens Care Materialssubstrate

JST Project

(The University of Tokyo)

Clinical Test

10

Company : NOF Corp.Development : 1994 – 1999JST funds: c.a. $8million

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No 1 Success Story4.Remarkable OutputsINTRO/Overview

Commercialization of GaN blue LED

No.1 Success Story

Inventor Isamu AKASAKI (Nagoya University)Company TOYODA GOSEI Co., Ltd.

JST funds $5.5 million

Royalty $52 million

JST project Mar 1987 - Sep 1990

11Mobile Phone Backlight

Traffic Signal Large Full-color Display

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Program: Tech Transfer Activities10:00- Overview of JST's Technology Transfer Activities

C titi F di P

Program: Tech Transfer Activities

Competitive Funding Programs

10:10- □ New Technology transfer Program “A-STEP” Bottom-up

10:20- □ Strategic Promotion of Innovative Research Top-down10:20- □ Strategic Promotion of Innovative Research and Development

Top down

10:35- □ Comprehensive Support Programs for C ti f R i l I ti

RegionalCreation of Regional Innovation

10:50- Q&A(1)

Intellectual Property & Various supportsIntellectual Property & Various supports

11:00- □ The Circumstances of IP surrounding Japanese Universities and Our Mission

IP

11:15- □ Strategic support for acquisition and licensing of IPR

IP

11:30- □ Linking mechanism of research results to Support11:30 □ Linking mechanism of research results to practical application

pp

11:45- Q&A(2)12

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OutlineA-STEP 0.Outline

Outline

New Funding Program, "A-STEP"

1. Motivation2 Synopsis2. Synopsis3. Programs by scale

l4. Program Flow5. Proposals by Program & Field6. Summary

13

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Reorganization and Launching A STEPA-STEP 1.Motivation

1950 1960 1970 1980 1990 2000 2010 2020★Since 1958

Reorganization and Launching A-STEP1950 1960 1970 1980 1990 2000 2010 2020★

funding programA-STEP

FY2008 FY2009

S

Pros Cons Pros & Pros?

All Japan Four divisionspBottom-upSelection of 7

Difficult to identify most suitable

One divisionUnified

programsWide range of

R&D processes

programDifficult to accessApplication unique

application

14

R&D processes Application unique to each program

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A STEPA-STEP 2.Synopsis

A-STEPProposals by university-company Proposals by university company partners

Calls for applications twice a year (FY2009)Calls for applications twice a year (FY2009)

Seamlessly integrates wide range of R&D f l h t R&D from early phase to mass production.

Feasibility Study (2 programs)Full Scale R&D (6 programs) ( p g )

Covers all fields of science and technology including medical sciences

15

technology, including medical sciences

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What does A STEP stand for?A-STEP 2.Synopsis

What does A-STEP stand for?The answer is ・・・The answer is

“Adaptable and Seamless T h l T f P Technology Transfer Program through Target-Driven R&D.”

B i Applied Scale-up/BasicResearch

AppliedResearch/Development

Scale up/CommercialOperation

16

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Programs by Scale(1)A-STEP 3. Programs by scale

Programs by Scale(1)Phase I : Feasibility Study

Program up to Budget Fund type

Phase I : Feasibility Study

Seeds Validation 1yr Grant

Start-up Validation 1yr Grant

- $100K

- $100K

17

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Programs by Scale(2)A-STEP 3. Programs by scale

Programs by Scale(2)Phase II : Full-Scale R&D Commercialization

Program up to Budget Fund type

Phase II : Full Scale R&D Commercialization

High-risk Challenge 2yrs Grant

Venture Program 3yrs Grant

- $200K

- $1.5millionVenture Program 3yrs

Promoting R&D 4yrs Matching fund

d d

- $2 million

Small Business 5yrs Conditioned fund

Drug Discovery 5yrs Conditioned

- $3million

- $10million Drug Discovery 5yrs fund

Contract 7yrs Risk-taking - $20million

18Development

7yrs gfund

$20million

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Program Flow: Plan OptimizationA-STEP 4. Program Flow

Program Flow: Plan OptimizationPhase I Application Reception section× FeasibilityStudy

Application

Peer review

Reception sectionCompaniesUniversities

××

×Peer review

Pl ti i ti

Documentary examination

c.a.100 projects per year (FY2009)

Plan optimization

h ll l

Peer reviewinterview

Phase II Full-Scale R&Dc.a.50projects per year

•High-risk Challenge•Venture Program

•Small Business•Drug Discovery

19

(FY2009)Venture Program

•Promoting R&DDrug Discovery

•Contract Development

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Peer Review CriteriaA-STEP 4. Program Flow

Peer Review Criteria

N It Feasibility Full-Scale No. Item

1 Originality, novelty, competitive edge and availability

Feasibility Study

Full Scale R&D

edge and availability

2 Validity of target setting

3 Possibility of making innovation

E ti ibilit f 4 Execution possibility of proposed action plan

5 C i li ti P ibilit5 Commercialization Possibility

6 Risk in developmentp

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Proposals by ProgramA-STEP 5. Proposals by Program & Field

Proposals by Program(FY2009, 1st)

Full-Scale Feasibility R&D

Feasibility Study

# f l21

# of proposals

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Proposals by FieldA-STEP 5. Proposals by Program & Field

Proposals by Field(FY2009, 1st)

44%Life ScienceLife science

17%

13%

Nanotechnology/Material

ITIT

Nanotech/Material Four priority fields79%

4%

4%

Energy

EnvironmentEnvironment

Energy

79%

14%

3%

manufacturing technology

infrastructureInfrastructure

Manufacturing

0% 10% 20% 30% 40% 50%

22

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To bridge the gaps in R&D pipelineA-STEP 6. Summary

To bridge the gaps in R&D pipeline

BasicResearch

AppliedResearch/Development

Scale-up/CommercialOperationResearch Development Operation

River of Magic

Valley of Death

River of Magic

Darwinian Sea

23

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SummaryA-STEP 6. Summary

Summary

A-STEP bridges the gap between the research lab and the market place.

A-STEP places particular emphasis on the next generation of creative and the next generation of creative and innovative science and technology.

24

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Thank you for your attentionThank you for your attention

25

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[APPENDIX] A-STEP Program

~APPENDIX ~~APPENDIX ~

26

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[APPENDIX] A-STEP Program

A STEP PProgram up to Budget Fund type

A-STEP Program

Phase-I

Feasibility Study

Seeds Validation 1yr Grant

Start-up Validation 1yr Grant

- $100K

- $100K

High-risk Challenge 2yrs Grant

Venture Program3yrs Grant

- $200K

- $1.5million

Phase II

Promoting R&D4yrs Matching

fund- $2 million

Phase-II

Full-ScaleR&D

Small Business 5yrs Conditioned fund

Drug Discovery5yrs Conditioned

- $3million

- $10million 5yrs fund

Contract D l t 7 Risk-taking

$

- $20million

27

Development 7yrs Risk taking fund

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Phase I (Feasibility Study)[APPENDIX] A-STEP Program

Phase I (Feasibility Study)

■Feasibility Study■Feasibility Study

one year ~$100K

to examine the possibility of commercial

one year, ~$100K

p yviability of research results obtained in academia(1) seeds validation(2) start up validation(2) start-up validation

JSTcompanyuniversityGrant

28

JST university

development supporter ※start-up

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Phase II (High risk Challenge)[APPENDIX] A-STEP Program

Phase II (High-risk Challenge)

■High risk Challenge Program■High-risk Challenge Program

~two years ~$200K

to help companies pursue high-risk R&D

~two years, ~$200K

p p p gProposals has the potential for high impact, but that are too novel or at a stage too early to for companies to invest private funding. Target is to relay results of this program closer

h i li ito the commercialization.

G t company29

JSTGrant companyuniversity

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Phase II (Venture Program)[APPENDIX] A-STEP Program

Phase II (Venture Program)

■Venture Program■Venture Program

~three years ~$1 5million

to support start up university venture

~three years, ~$1.5million

pp p yProposal are submitted by jointly R&D representative, entrepreneur, and development supporter.Entrepreneur orient, guide and advise project

d d b hi f f and expected to be chief of a start-up.

JSTGrantR&D representative

t 30

Grantdevelopment supporter

entrepreneur

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Phase II (Promoting R&D)[APPENDIX] A-STEP Program

Phase II (Promoting R&D)

■Promoting R&D Program■Promoting R&D Program

~four years, ~$2million

to help companies promote high-risk

four years, $2million

p p p glong-term R&D

JST ≦

matching fund

JST company (capitalized at ≦$10 million)

JST

1:1

31JST company (capitalized at >$10 million)

2:1

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Phase II (Small Business)[APPENDIX] A-STEP Program

Phase II (Small Business)

■Small Business Program■Small Business Program

~five years, ~$3million

to help small and medium sized companies(*) ca o t de elopment fo companies(*) carry out development for commercialization

l d $ ll d l(*) : capitalized at $10 million and lessThe business plan is evaluated as well as

C diti d f d JST company

development plan.

32

Conditioned fund JST company

Royaltypatent holder(s)

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Phase II (Drug Discovery)[APPENDIX] A-STEP Program

Phase II (Drug Discovery)

■Drug Discovery Program■Drug Discovery Program

~five years, ~$10milliony ,

to help pharmaceutical company carry out drug discovery development.

Company must be capitalized at $300 illi d lmillion and less.

Target is to complete phase IIA clinical trial. Development result is expected to move on to phase II-b clinical trial by applicant, licensing out or alliances with another

33

licensing out, or alliances with another pharmaceutical company.

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Phase II (Contract Development)[APPENDIX] A-STEP Program

Phase II (Contract Development)

■Contract Development Program■Contract Development Program

~seven years,y ,~$20million

to support companies challenge the commercialization R&D with a business plancommercialization R&D with a business plan

by the up-front budget of at most $20million$20millionby JST’s taking a potential risk in the new technology

34

new technology

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Phase II (Contract Development)[APPENDIX] A-STEP Program

Phase II (Contract Development)

■Contract Development Program

“Risk-taking” fund

■Contract Development Program

~seven years,Risk-taking fund

(1)if R&D is successful (2)if R&D is unsuccessful

y ,~$20million

company

( ) (2)if R&D is unsuccessful

companyJST 100%

repayment 10% repayment

JST

Royalty

p y p y

P t t h ld ( )35

Patent holder(s)