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Technology Transfer Activity ①
Overview of JST's Technology T f A ti iti & N Transfer Activities & New Funding Program, "A-STEP"Funding Program, A STEP
September 15th, 2009
Miho OKISHIRO
Department of Industry-Academic Collaboration
Japan Science and Technology Agency
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Program: Tech Transfer Activities
C titi F di P
Program: Tech Transfer Activities10:00- Overview of JST's Technology Transfer Activities
Competitive Funding Programs
10:10- □ New Technology transfer Program “A-STEP" Bottom-up
10:20- □ Strategic Promotion of Innovative Research Top-down10:20 □ Strategic Promotion of Innovative Research and Development
Top down
10:35- □ Comprehensive Support Programs for Creation of Regional Innovation
RegionalCreation of Regional Innovation
10:50- Q&A(1)
Intellectual Property & Various supportsIntellectual Property & Various supports
11:00- □ The Circumstances of IP surrounding Japanese Universities and Our Mission
IP
11:15- □ Strategic support for acquisition and licensing of IPR
IP
11:30- □ Linking mechanism of research results to Supportgpractical application
pp
11:45- Q&A(2)
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OutlineINTRO/Overview 0.Outline
Outline
Overview of JST’s Technology Transfer Activities
1. Mission2. Programs: Two Approaches3 Timeline of Tech Transfer History3. Timeline of Tech Transfer History4. Remarkable Outputs
3
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MissionINTRO/Overview 1.Mission
:To bridge the gaps in R&D pipelineMissionJST advances returning of research
:To bridge the gaps in R&D pipelineg
results generated at universities to the society and nation. y
BasicR h
AppliedResearch/
Scale-up/Commercial
Research/
Development Operation
River of Magic
4Valley of Death
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INTRO/Overview 1.Mission
New Energy and Industrial Technology Development
5
Referred from Mr. Furukawa’s presentation (Sep. 14th)
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INTRO/Overview
Two
2.Programs
1.COMPETITIVE FUNDINGApproaches 【BOTTOM-UP】
A-STEPNew
ACADEMIA【TOP-DOWN】
Strategic Promotion of Innovative New
Universities
Research and Development
【REGIONAL】Comprehensive Support Programs for Partly New
2 Tech Transfer Support
Public Research Institutes
BUSINESS
START-UP
Comprehensive Support Programs for Creation of Regional Innovation
2.Tech Transfer SupportLinking mechanism of research resultsto practical application
TLOs
JST
Center for Intellectual Property Strategies
NEW
PRIVATECOMPANY
6Strategy PlanningCOMPANY
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Increasing Collaborative R&D2.ProgramsINTRO/Overview
Increasing Collaborative R&DCollaborative research continue to increase in number and expenditures.
20,000 500
Collaborative R&D at Universities
15,000
ts
400
R&D expenditures Number of
10,000
# o
f pr
ojec
t
200
300 R&D expenditures acquired from
external sources [$ million]
Number of projects
5,000100
TOTAL 80%
7
02003 2004 2005 2006 2007 2008
0company80%
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Timeline of Tech Transfer HistoryINTRO/Overview 3. Timeline of Tech Transfer History
Timeline of Tech Transfer History1950 1960 1970 1980 1990 2000 2010 2020★
Since 1958JST1950 1960 1970 1980 1990 2000 2010 2020★
funding program
Economy1950 1960 1970 1980 1990 2000 2010 2020
Licensing program etc.
economicrecovery
economicgrowth
trade conflicts
bubble economy
lostdecade
sustainable growth
1950 1960 1970 1980 1990 2000 2010 2020
groundbreakingyears
f i h l i l
independentcreative technology
globalization collaborative science
8
foreign technologicalintroduction Revolutionary era
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Timeline of Tech Transfer HistoryINTRO/Overview 3. Timeline of Tech Transfer History
Timeline of Tech Transfer History1950 1960 1970 1980 1990 2000 2010 2020★
Since 1958JST1950 1960 1970 1980 1990 2000 2010 2020★
funding programuniversity-i d t
emphasis on industrycollaboration
emphasis on intellectual property
Economy1950 1960 1970 1980 1990 2000 2010 2020
Licensing program etc.
University’s restructuringeconomicrecovery
economicgrowth
trade conflicts
bubble economy
lostdecade
sustainable growth
1950 1960 1970 1980 1990 2000 2010 2020
▼Japanese Bayh-Dole Act (1995)
▼The Basic Law on Science and Technology
University s restructuring
groundbreakingyears
f i h l i l
independentcreative technology
globalization collaborative science
▼Japanese Bayh Dole Act
▼Council for Science and Technology Policy(1999)
(2001)▼Japan's national universities became
i d d t ti l ti(2004)
9
foreign technologicalintroduction Revolutionary era
independent national corporations(2004)
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Remarkable Outputs4.Remarkable OutputsINTRO/Overview
Remarkable OutputsManufacturing technology of biocompatible MPC polymer
MPC Polymer
Medical Device
Application
h d h bi difi ti
Coating Materials(e.x. artificial heart)
PC
Cosmetics coating
hydrophobic modification
Contact Lens
SUCCESS in acquiring a new market
PC
Cosmetics MaterialsINVENTORS :
●Nobuo NAKABAYASHI(Tokyo Medical and Dental University)
●Kazuhiko ISHIHARA
Contact Lens Care Materialssubstrate
JST Project
(The University of Tokyo)
Clinical Test
10
Company : NOF Corp.Development : 1994 – 1999JST funds: c.a. $8million
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No 1 Success Story4.Remarkable OutputsINTRO/Overview
Commercialization of GaN blue LED
No.1 Success Story
Inventor Isamu AKASAKI (Nagoya University)Company TOYODA GOSEI Co., Ltd.
JST funds $5.5 million
Royalty $52 million
JST project Mar 1987 - Sep 1990
11Mobile Phone Backlight
Traffic Signal Large Full-color Display
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Program: Tech Transfer Activities10:00- Overview of JST's Technology Transfer Activities
C titi F di P
Program: Tech Transfer Activities
Competitive Funding Programs
10:10- □ New Technology transfer Program “A-STEP” Bottom-up
10:20- □ Strategic Promotion of Innovative Research Top-down10:20- □ Strategic Promotion of Innovative Research and Development
Top down
10:35- □ Comprehensive Support Programs for C ti f R i l I ti
RegionalCreation of Regional Innovation
10:50- Q&A(1)
Intellectual Property & Various supportsIntellectual Property & Various supports
11:00- □ The Circumstances of IP surrounding Japanese Universities and Our Mission
IP
11:15- □ Strategic support for acquisition and licensing of IPR
IP
11:30- □ Linking mechanism of research results to Support11:30 □ Linking mechanism of research results to practical application
pp
11:45- Q&A(2)12
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OutlineA-STEP 0.Outline
Outline
New Funding Program, "A-STEP"
1. Motivation2 Synopsis2. Synopsis3. Programs by scale
l4. Program Flow5. Proposals by Program & Field6. Summary
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Reorganization and Launching A STEPA-STEP 1.Motivation
1950 1960 1970 1980 1990 2000 2010 2020★Since 1958
Reorganization and Launching A-STEP1950 1960 1970 1980 1990 2000 2010 2020★
funding programA-STEP
FY2008 FY2009
S
Pros Cons Pros & Pros?
All Japan Four divisionspBottom-upSelection of 7
Difficult to identify most suitable
One divisionUnified
programsWide range of
R&D processes
programDifficult to accessApplication unique
application
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R&D processes Application unique to each program
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A STEPA-STEP 2.Synopsis
A-STEPProposals by university-company Proposals by university company partners
Calls for applications twice a year (FY2009)Calls for applications twice a year (FY2009)
Seamlessly integrates wide range of R&D f l h t R&D from early phase to mass production.
Feasibility Study (2 programs)Full Scale R&D (6 programs) ( p g )
Covers all fields of science and technology including medical sciences
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technology, including medical sciences
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What does A STEP stand for?A-STEP 2.Synopsis
What does A-STEP stand for?The answer is ・・・The answer is
“Adaptable and Seamless T h l T f P Technology Transfer Program through Target-Driven R&D.”
B i Applied Scale-up/BasicResearch
AppliedResearch/Development
Scale up/CommercialOperation
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Programs by Scale(1)A-STEP 3. Programs by scale
Programs by Scale(1)Phase I : Feasibility Study
Program up to Budget Fund type
Phase I : Feasibility Study
Seeds Validation 1yr Grant
Start-up Validation 1yr Grant
- $100K
- $100K
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Programs by Scale(2)A-STEP 3. Programs by scale
Programs by Scale(2)Phase II : Full-Scale R&D Commercialization
Program up to Budget Fund type
Phase II : Full Scale R&D Commercialization
High-risk Challenge 2yrs Grant
Venture Program 3yrs Grant
- $200K
- $1.5millionVenture Program 3yrs
Promoting R&D 4yrs Matching fund
d d
- $2 million
Small Business 5yrs Conditioned fund
Drug Discovery 5yrs Conditioned
- $3million
- $10million Drug Discovery 5yrs fund
Contract 7yrs Risk-taking - $20million
18Development
7yrs gfund
$20million
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Program Flow: Plan OptimizationA-STEP 4. Program Flow
Program Flow: Plan OptimizationPhase I Application Reception section× FeasibilityStudy
Application
Peer review
Reception sectionCompaniesUniversities
××
×Peer review
Pl ti i ti
Documentary examination
c.a.100 projects per year (FY2009)
Plan optimization
h ll l
Peer reviewinterview
Phase II Full-Scale R&Dc.a.50projects per year
•High-risk Challenge•Venture Program
•Small Business•Drug Discovery
19
(FY2009)Venture Program
•Promoting R&DDrug Discovery
•Contract Development
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Peer Review CriteriaA-STEP 4. Program Flow
Peer Review Criteria
N It Feasibility Full-Scale No. Item
1 Originality, novelty, competitive edge and availability
Feasibility Study
Full Scale R&D
edge and availability
2 Validity of target setting
3 Possibility of making innovation
E ti ibilit f 4 Execution possibility of proposed action plan
5 C i li ti P ibilit5 Commercialization Possibility
6 Risk in developmentp
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Proposals by ProgramA-STEP 5. Proposals by Program & Field
Proposals by Program(FY2009, 1st)
Full-Scale Feasibility R&D
Feasibility Study
# f l21
# of proposals
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Proposals by FieldA-STEP 5. Proposals by Program & Field
Proposals by Field(FY2009, 1st)
44%Life ScienceLife science
17%
13%
Nanotechnology/Material
ITIT
Nanotech/Material Four priority fields79%
4%
4%
Energy
EnvironmentEnvironment
Energy
79%
14%
3%
manufacturing technology
infrastructureInfrastructure
Manufacturing
0% 10% 20% 30% 40% 50%
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To bridge the gaps in R&D pipelineA-STEP 6. Summary
To bridge the gaps in R&D pipeline
BasicResearch
AppliedResearch/Development
Scale-up/CommercialOperationResearch Development Operation
River of Magic
Valley of Death
River of Magic
Darwinian Sea
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SummaryA-STEP 6. Summary
Summary
A-STEP bridges the gap between the research lab and the market place.
A-STEP places particular emphasis on the next generation of creative and the next generation of creative and innovative science and technology.
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Thank you for your attentionThank you for your attention
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[APPENDIX] A-STEP Program
~APPENDIX ~~APPENDIX ~
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[APPENDIX] A-STEP Program
A STEP PProgram up to Budget Fund type
A-STEP Program
Phase-I
Feasibility Study
Seeds Validation 1yr Grant
Start-up Validation 1yr Grant
- $100K
- $100K
High-risk Challenge 2yrs Grant
Venture Program3yrs Grant
- $200K
- $1.5million
Phase II
Promoting R&D4yrs Matching
fund- $2 million
Phase-II
Full-ScaleR&D
Small Business 5yrs Conditioned fund
Drug Discovery5yrs Conditioned
- $3million
- $10million 5yrs fund
Contract D l t 7 Risk-taking
$
- $20million
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Development 7yrs Risk taking fund
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Phase I (Feasibility Study)[APPENDIX] A-STEP Program
Phase I (Feasibility Study)
■Feasibility Study■Feasibility Study
one year ~$100K
to examine the possibility of commercial
one year, ~$100K
p yviability of research results obtained in academia(1) seeds validation(2) start up validation(2) start-up validation
JSTcompanyuniversityGrant
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JST university
development supporter ※start-up
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Phase II (High risk Challenge)[APPENDIX] A-STEP Program
Phase II (High-risk Challenge)
■High risk Challenge Program■High-risk Challenge Program
~two years ~$200K
to help companies pursue high-risk R&D
~two years, ~$200K
p p p gProposals has the potential for high impact, but that are too novel or at a stage too early to for companies to invest private funding. Target is to relay results of this program closer
h i li ito the commercialization.
G t company29
JSTGrant companyuniversity
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Phase II (Venture Program)[APPENDIX] A-STEP Program
Phase II (Venture Program)
■Venture Program■Venture Program
~three years ~$1 5million
to support start up university venture
~three years, ~$1.5million
pp p yProposal are submitted by jointly R&D representative, entrepreneur, and development supporter.Entrepreneur orient, guide and advise project
d d b hi f f and expected to be chief of a start-up.
JSTGrantR&D representative
t 30
Grantdevelopment supporter
entrepreneur
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Phase II (Promoting R&D)[APPENDIX] A-STEP Program
Phase II (Promoting R&D)
■Promoting R&D Program■Promoting R&D Program
~four years, ~$2million
to help companies promote high-risk
four years, $2million
p p p glong-term R&D
JST ≦
matching fund
JST company (capitalized at ≦$10 million)
JST
1:1
31JST company (capitalized at >$10 million)
2:1
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Phase II (Small Business)[APPENDIX] A-STEP Program
Phase II (Small Business)
■Small Business Program■Small Business Program
~five years, ~$3million
to help small and medium sized companies(*) ca o t de elopment fo companies(*) carry out development for commercialization
l d $ ll d l(*) : capitalized at $10 million and lessThe business plan is evaluated as well as
C diti d f d JST company
development plan.
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Conditioned fund JST company
Royaltypatent holder(s)
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Phase II (Drug Discovery)[APPENDIX] A-STEP Program
Phase II (Drug Discovery)
■Drug Discovery Program■Drug Discovery Program
~five years, ~$10milliony ,
to help pharmaceutical company carry out drug discovery development.
Company must be capitalized at $300 illi d lmillion and less.
Target is to complete phase IIA clinical trial. Development result is expected to move on to phase II-b clinical trial by applicant, licensing out or alliances with another
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licensing out, or alliances with another pharmaceutical company.
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Phase II (Contract Development)[APPENDIX] A-STEP Program
Phase II (Contract Development)
■Contract Development Program■Contract Development Program
~seven years,y ,~$20million
to support companies challenge the commercialization R&D with a business plancommercialization R&D with a business plan
by the up-front budget of at most $20million$20millionby JST’s taking a potential risk in the new technology
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new technology
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Phase II (Contract Development)[APPENDIX] A-STEP Program
Phase II (Contract Development)
■Contract Development Program
“Risk-taking” fund
■Contract Development Program
~seven years,Risk-taking fund
(1)if R&D is successful (2)if R&D is unsuccessful
y ,~$20million
company
( ) (2)if R&D is unsuccessful
companyJST 100%
repayment 10% repayment
JST
Royalty
p y p y
P t t h ld ( )35
Patent holder(s)