philippine council for health research and …

134th PCHRD Anniversary Report

PHILIPPINE COUNCIL FOR HEALTH RESEARCH AND DEVELOPMENT

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CONTENTS

PROGRAM

8:30 AM OPENING PROGRAMDoxologyPhilippine National Anthem

UP CONCERT CHORUS

Welcome Remarks Dr. Jaime C. MontoyaExecutive Director, PCHRD

Message Secretary Mario G. MontejoDOST

Secretary Janette P. Loreto-GarinDOH

Keynote Address Dr. M. Jamal DeenPresident, Academy of ScienceRoyal Society of Canada

9:30 AM AWARDING 2016 PHREB Accredited Ethics Review Committees

10:00 AM BREAK

Program 2

Introduction 4

PCHRD Anniversary in Numbers 5

Opening Messages 6

Keynote Lecture 7

Panel Discussion 8

Research Dissemination Sessions 12

Workshop, IP Forum, Convention 13

Side Meetings 14

Awarding of Newly Accredited Ethics Review Committees (ERCs)

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APAME Asia Pacific Association of Medical Journal Editors

ASEAN-NDI ASEAN Network for Drugs, Diagnostics, Vaccines and Traditional Medicines Innovation

AUF Angeles University Foundation

CEU Centro Escolar University

COHRED Council on Health Research for Development

DLSHSI De La Salle Health Sciences Institute

DOH Department of Health

LIST OF ABBREVIATIONS

DOH HSRM Department of Health Health Systems Research Management

DOST Department of Science and Technology

FNRI Food and Nutrition Research Institute

NUHRA National Unified Health Research Agenda

PAMJE Philippine Association of Medical Journal Editors

PBDIC Philippine Biomedical Device Innovation Consortium

PCHRD Philippine Council for Health Research and Development

PET Positron Emission Tomography

PHREB Philippine Health Research Ethics Board

PIDS Philippine Institute for Development Studies

PNHRS Philippine National Health Research System

PRC Professional Regulation Commission

PSS PCHRD Scholars’ Society

RFI Research Fairness Initiative

SMAM School-based Mosquito Abundance Model

UERMMMC University of the East Ramon Magsaysay Memorial Medical Center

UK United Kingdom

UP University of the Philippines

UST University of Santo Tomas

WPRIM Western Pacific Index Medicus


10:15 AM PANEL DISCUSSIONInternational Partnerships and Fairness in Research Collaboration: Learnings, Best Practices, and the Way Forward

Moderator:Dr. Manuel DayritDean, Ateneo School of Medicine and Public Health

Speaker: Prof. Carel IJsselmuidenExecutive Director, COHRED

Panelists:Dr. Lilibeth DavidUndersecretary, DOH

Ms. Karen Ann HipolResearch and Innovation Programme Manager, UK-Newton Fund

Dr. Carmencita D. PadillaChancellor, UP Manila

Dr. Charles YuVice Chancellor for Mission and Linkages, De La Salle University

Dr. Anavaj SakuntabhaiHead of Functional Genetics Laboratory, Institut Pasteur

Dr. Cecilia AcuinChief SRS, FNRI

11:45 AM CLOSING REMARKS Dr. Carmencita D. PadillaChancellor, UP Manila

12:00 NN LUNCH

INTERMISSION UP Concert Chorus

Ms. Merlita OpeñaDivision Chief, PCHRDMaster of Ceremonies

AFTERNOON PARALLEL SESSIONS

Dissemination of Key Findings: Moving Forward and Overcoming Challenges: Focus on the Non-Visible Faces 11/2013 Typhoon Yolanda Disaster in LeyteVenue: New World Ballroom 2

Dengue Forum: School-Based Mosquito Abundance Prediction Model for Mosquito Density Venue: New World Ballroom 1

Meeting on Biomedical Devices (PBDIC with Dr. M. Jamal Deen) (by invitation only)Venue: Gallery I

Orientation Forum on DOST Intellectual Property PoliciesVenue: New World Ballroom 3

PAMJE General AssemblyVenue: Press Room 3

PCHRD Scholars’ Society AssemblyVenue: Balcony 2

Workshop on RFIVenue: Balcony 1

18 March 2016 | Dusit Thani Manila, Makati CityConsultation Meeting on Research on Health and the Environment / Disaster Risk Reduction

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Celebrating the Anniversary with its partners in the health research system every 17 March has been a tradition for the PCHRD. The event is just one of the platforms where the Council presents its accomplishments, discusses timely issues in health research, and presents opportunities for collaboration.

On its 34th year, the Council focused its celebration on staunch partnerships with different local and global institutions not only in health but also from other sectors of society, thus, the chosen theme, “Going Global: Increasing International Partnerships in Research and Innovation for Health.”

Highlight of the program was the keynote lecture of Dr. Mohamed Jamal Deen, President of the Royal Society of Canada Academy of Science, on smart sensors for the grand challenges in health applications.

The program also includes panel discussion on learnings, best practices, and way forward on international partnerships and fairness in research collaboration. In the afternoon, seven parallel sessions were organized: 1) Dissemination of Key Findings: Moving Forward and Overcoming Challenges: Focus on the Non-Visible Faces 11/2013 Typhoon Yolanda Disaster in Leyte; 2) Dengue Forum: School-Based Mosquito Abundance Prediction Model for Mosquito Density; 3) Meeting on Biomedical Devices; 4) Orientation Forum on DOST Intellectual Property Policies; 5) Workshop on Research Fairness Initiative; and general assemblies of the 6) PAMJE and 7) PCHRD Scholars’ Society.

INTRODUCTION


719Total

Registered300

Academe

90Hospital

32Industry

18LGU

154National

Government12NGO

36Association and

Specialty Society

77Others

PCHRD ANNIVERSARY IN NUMBERS

http://clipart-library.com

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OPENING MESSAGES

DR. JAIME C. MONTOYAExecutive Director, PCHRD

Welcome Remarks

Thankful to its partners, Dr. Montoya shared the important outputs of the recent year that are products of the DOST and the Council’s longstanding local and international partnerships. As lead of the PNHRS, the support from the 17 Regional Health Research and Development Consortia are crucial to extend the Council’s programs and services to the regions. Significant partnerships such as that of the DOH, CHED, UP National Institutes of Health, PBDIC, UK Medical Research Council, Institut Pasteur, ASEAN-NDI, WPRIM, APAME, and COHRED, generated new heights in finding solutions to achieve health equity, eliminating disparities, and improving the overall health of the population.

SEC. MARIO. G. MONTEJOSecretary, DOST

Message

As one of the sectoral Councils of the DOST, Sec. Montejo congratulated the Council for its contributions to the Department’s collective vision of S&T-based and innovation-driven Philippines. The rigorous effort of the Council to establish national, regional, and international partnerships was mentioned important for generating new solutions for health problems and concerns. Aside from the priority projects supported and monitored by PCHRD, he also enumerated some of the projects which are products of local partnerships including the development of total knee replacement system, distal targeting device, ventilator, and portable diagnostic device. For international collaboration, he mentioned the funding from the UK Newton Fund Program which supported six ongoing projects.

SEC. JANETTE LORETO-GARIN Secretary, DOH

Delivered by: ASST. SEC. MARIA-BERNARDITA T. FLORES, CESO II, Executive Director IVNational Nutrition Council

Message

The DOH Secretary acknowledged the leadership and directed advocacies of PCHRD for stronger health research culture in the country and for resource mobilization to generate knowledge, technologies and innovations. She recognized the role of partnerships and collaborations in research and development that can hasten completion of researches. To continue to strengthen health researches, the Secretary urged PCHRD to continue its course in the following tracks: (1) mobilization of human resources for health through its scholarship grants, (2) use of information and communication technology in health research such as telehealth, (3) making health researches accessible through regional networks for health, and (4) providing opportunities for collaboration and partnerships within and beyond our borders.


In his lecture, Dr. M. Jamal Deen, a world-leading expert in modelling, design, and applications of modern advanced semiconductor devices and circuits, presented the 14 grand challenges for engineering in the 21st century as follows: 1) advance personalized learning, 2) economical solar energy, 3) enhance virtual reality, 4) reverse engineer

the brain, 5) engineer better medicines, 6) advanced health informatics, 7) restore and improve urban infrastructure, 8) secure cyberspace, 9) provide access to clean water, 10) provide energy form fusion, 11) prevent nuclear terror, 12) manage nitrogen cycle, 13) develop carbon sequestration methods, and 14) engineer tools for scientific discovery.

In the case of the health care industry, Dr. Deen explained that rising costs, changing demographics, and quality of care were three interlocking crises that make present health care system unsustainable. These three crises become the drivers for change.

An important solution to these challenges, as discussed by Dr. Deen, was the increased use of technology. The use of technology can improve the process, quality of practices, and regulatory compliance. Presented some of his significant health application projects, Dr. Deen highlighted the Ubiquitous-Healthcare (U-Health), a new area in the field of technology which makes use of sensors and motor devices to monitor and improve body conditions among patients, which offers potential areas for partnership and collaboration.

KEYNOTE LECTURE

DR. MOHAMED JAMAL DEENPresident, Royal Society of Canada Academy of Science

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PANEL DISCUSSION

International Partnerships and Fairness in Research Collaboration: Learnings, Best Practices, and the Way Forward

RESEARCH FAIRNESS INITIATIVE

PROF. CAREL IJSSELMUIDENExecutive Director, COHRED

COHRED Executive Director Prof. Carel IJsselmuiden presented the COHRED’s Research Fairness Initiative, a reporting system that encourages governments,

business, organizations, and funders to describe how they take measures to create trusting, lasting, transparent, and effective partnerships in research and innovation.

As cited by Prof. IJsselmuiden, the problem that RFI would like to address was the systematically unfair outcomes between partnering research institutions in terms of ability to shape the research agenda, the competitiveness of scientific productivity and impact, and capacity building. It also hopes to solve issues on unequal right for credit and recognition for contribution, data access to intellectual property, and compensation for participation in research partnerships among research institutions globally. The RFI hopes to improve research partnerships that have impact on health, globally and locally – emphasizing the health of those in lowest income situations and countries.


DR. LILIBETH C. DAVIDUndersecretary, Office for Policy and Health Systems, DOH

How the Department engages in research partnerships and collaborations and how fairness in research collaborations is achieved were the highlight of the presentation of Dr. Lilibeth C. David, Undersecretary Office for Policy and Health Systems of the DOH.

Dr. David reported that out of the 279 researches generated from 2001-2011, 194 had been translated into policies and 236 into programmatic recommendations. She explained that most research projects in DOH were programmatic and operational in nature and were contracted out to institutions and funded by partners. According to Dr. David, the DOH-HSRM Program was a strategy started in 2012 to address issues on health research implementation and management. The program engages other government research institutions as institutional partners to generate research and build capacity to strengthen the health policy and research system management, and policy, plan, and program development. The PCHRD and PIDS were the managers of the DOH-HSRM Program.

According to Dr. David, fairness in research collaboration is evident in the opportunity, benefit-sharing, and process of the Department. In terms of opportunity, the Department follows the implementation of a research agenda that is aligned with the NUHRA and Kalusugan Pangkalahatan / Universal Health Care. The programs are implemented by partner institutions with technical competence in research and contracting mechanisms that caters both to large and small researchers. To ensure benefits of research is shared, proponents are required to publish their researches and present them in local and international research fora. On the issue of ethics, all researches are required to undergo ethics review.

The way towards fair research collaboration requires strengthened capacity of more researchers and research institutions, increased and institutionalization of incentives for researchers, collaboration and twinning arrangements between international and local research institutions for research, and need for more awareness and use of the COHRED RFI.

DR. CECILIA S. ACUINChief Science Research Specialist, FNRI

Guided by her experiences working from a government research institution, Dr. Cecilia S. Acuin, Chief Science Research Specialist, FNRI, shared important factors to consider when talking about research fairness such as inclusiveness, feedback and communication channels, transparency, and accountability.

Inclusiveness means no researcher or research institution is left behind. Dr. Acuin narrated past experiences wherein research opportunities had been selectively offered to some researchers or research institutions with track record. She also described the experiences of her friends in the regions who do not have easy access to funds and capacity building initiatives because these opportunities were concentrated in Manila. Dr. Acuin emphasized the need to empower budding researchers and provide more opportunities to small research institutions and non-government organizations all over the country.

In attaining fair benefit sharing, Dr. Acuin stressed the importance of feedback and communication which she thought is not explicitly seen in the fairness index. Before talking about opportunities and the RFI process, she pointed out that the first thing the index should answer is the question, “Who benefits in the end?” Dr. Acuin recommended to refine priorities by looking at the perspective of the beneficiaries instead of considering only the perspective of funders.

The importance of transparency wherein research results are communicated to everyone was highlighted during the discussion. From determining the research objectives up to dissemination of results, all stakeholders should be informed.

Lastly, accountability of both researchers and research funders should be clear to both parties. The question of who is supposed to be accountable for what should be strictly stipulated from the very beginning of the research undertaking.

Research Partnerships and Collaborations: Government Perspective

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DR. ANAVAJ SAKUNTABHAIHead, Functional Genetics Laboratory, Institut Pasteur Paris

On establishing a successful collaboration, Dr. Anavaj Sakuntabhai, Head, Functional Genetics Laboratory, Institut Pasteur Paris stressed the importance of interpersonal relationship, mutual benefit, and accountability. Dr. Sakuntabhai explained that successful collaboration is rooted in a goal that is geared toward the benefits of both partners, good relationship between collaborating institutions, and clear description of expectations and accountabilities.

Dr. Sakuntabhai viewed the RFI as a very good initiative and hoped that this will further enhance collaborations among countries.

MS. KAREN ANN HIPOLResearch and Innovation Program Manager,UK-Newton Fund

Creating strong, sustainable, and systematic links with science and innovation agencies, research institutions, and researchers, and promoting economic development and social welfare were key collaborative elements of the UK Newton Fund as presented by Ms. Karen Ann Hipol, Research and Innovation Program Manager, UK-Newton Fund. In case of the UK-Philippines Joint Health Research Call, Ms. Hipol discussed the three important stages which makes the partnership possible: (1) development of joint activity, (2) call process, and (3) funding awards.

In the development of joint activity, key partners are required to identify their commitment and counterpart funding, joint science priorities, kind of working relationship, means of communication, and team resources and tools.

The call process determines the willingness of partners to negotiate wherein realistic activities are detailed into plans and policies of funding agencies on Intellectual Property, collaborative agreements, and ethics approval.

The awarding of funds go through a joint panel where decisions are based on mutual and agreed criteria and timely sign off are made by governing bodies.

Building Successful International Research Collaborations: International Organization Perspective


DR. CARMENCITA D. PADILLAChancellor, UP Manila

In her response to the lecture on RFI, Dr. Carmencita D. Padilla, Chancellor, UP Manila, encouraged everyone to read the document to have an understanding on how the rest of the world address research. Dr. Padilla said that RFI is an excellent guide for the academe to make sure all of the 17 points were addressed from fairness, benefit sharing, and conduct of the study.

On an individual level, the RFI is helpful in knowing how to benchmark with the rest of the world. Through the RFI, researchers doing similar studies can be identified, thus, the possibility of research collaboration. The tool will also be beneficial to the government in aligning research track with the rest of the world. The index also addresses international standards and is seen to help uphold due diligence and ethics.

On the factors that affect research collaboration, Dr. Padilla explained that passion for research and patience motivates researchers to do research. This is why the government should respond to the low compensation for researchers who are torn between their love for research and their responsibility to provide a decent life for their family, she stated. On patience, she reminded funding agencies that quality research outputs cannot happen overnight - it requires time.

DR. CHARLES YUVice Chancellor for Mission and Linkages, De La Salle University

Dr. Charles Yu, Vice Chancellor for Mission and Linkages, De La Salle University, described national and international research collaborations as a jigsaw puzzle piece where research institutions align in the best way to create a perfect fit. An attitude of equal, close and continuous communication, open and honest sharing of best practices, and admitting what is not known are important factors in achieving successful collaboration. Dr. Yu also explained how transparency in research facilitate collaboration. He said that RFI can help in levelling the playing field. It can also encourage and widen the Philippine research landscape to more players. Dr. Yu challenged the government on how research institutions will be incentivized when they participate in RFI.

Research Collaboration and Partnership: Academe Perspective

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RESEARCH DISSEMINATION SESSIONS

The session highlighted the key findings of the study, “The Aftermath of Typhoon Yolanda: Immediate Pre-disaster Responses and Post-disaster Effects,” which looked

at the disaster risk reduction and mitigation responses of the government and community with particular focus on the most vulnerable groups in Tacloban City. Part of the presentation were recommendations for policy formulation and development of plan for programmatic actions related to disaster risks mitigation and preparedness, relief and rehabilitation, recovery, and reconstruction efforts.

Mr. Jesse David, Chief Economic Development Specialist, National Economic Development Authority, reported on the updates on Typhoon Yolanda rehabilitation and recovery efforts. He also cited the importance of partnership among stakeholders, government and private institutions, NGOs, academe, development partner countries, funding institutions, and local communities in the success of the rehabilitation efforts.

The School-based Mosquito Abundance Model (SMAM), a predictive model that estimates mosquito density in public elementary and high schools in the Philippines

even without actual field vector surveillance, was presented by proponents from University of the Philippines Manila, Prof. Lilian A. De Las Llagas and Prof. Lisa Grace S. Bersales. SMAM was deemed relevant as it may serve as an early warning device to prompt the communities dengue transmission risk in their respective schools and urge them to do an aggressive mosquito search and destroy activities.

Dr. Frances E. Edillo, University of San Carlos Professor, Dr. Clarito U. Cairo, Jr., Dengue Prevention and Control Program Manager, DOH, Asst. Prof. Buenalyn Teresita Ramos-Mortel, Assistant Professor, University of the Philippines Manila, Ms. Rosalina De Guzman, Chief of Climate Data Section, Department of Science and Technology- Philippine Atmospheric Geophysical and Astronomical Services Administration served as reactors for the session.

The non-visible faces of 11/2013 Typhoon Yolanda in Leyte: Implications for forward-looking disaster risk reduction strategies

Dengue Forum: School-based Mosquito Abundance Prediction Model for Mosquito Density


Orientation Forum on DOST Intellectual Property Policies

An orientation forum for DOST and PCHRD researchers to learn and clarify the DOST Intellectual Property Management Protocol was led by Atty. Lucieden G. Raz,

Consultant of DOST - Technology Licensing Office Program.

Workshop on Research Fairness Initiative (RFI)

The workshop provided a venue to further discussions on COHRED’s proposed RFI. Still a work in progress, the RFI is the first global effort to create transparency, accountability, and opportunities to develop benchmarks, agree on ‘best practices’, and promote fairness in research collaborations. Practical reasons for adopting RFI, the problems RFI addresses, and its importance were among the topics discussed.

IP FORUM, WORKSHOP, CONVENTION

PCHRD Scholars’ Society Convention

Attended by the PCHRD Scholars’ Society (PSS) members, the yearly convention featured the President’s End-of-Term Report, the Election of Board of Directors for 2016 to 2018, amendments in the PSS constitution and by-laws, oath taking of the new members, and research projects presentation of the newly graduated PSS scholars.

Three scholars who have completed study within the last three years presented the results of their research.

• “Evaluation of serum microRNAs as potential biomarkers for chronic hepatitis B and non-alcoholic fatty liver disease” by Mr. Noel C. Salvoza of Saint Luke’s Medical Center

• “Ethnobotany, secondary metabolites, anti-oxidant activity and toxicity of selected wild fruits in Benguet, Cordillera Administrative Region” by Dr. Racquel T. Chua-Barcelo of Saint Louis University

• “Cacao (Theobroma cacao L.) proanthocyanidins and its interactions with artesunate and in-vitro physiological effect of such interactions in Jurkat Leukemia Cell Line” by Dr. Jacqueline Rose Burgos of University of the Philippines Los Banos

PCHRD Scholars’ Society Board of Directors 2016 - 2018

Position Name Institution

President Dr. Rommel Salazar DLSHSI

Vice

President Dr. Benida Fontanilla UERMMMC

SecretaryAssoc. Prof. Rogelio

CruzCEU

Treasurer Dr. Bella Panlilio AUF

PROProf. Mac Gerald

CuetoUERMMMC

Board

Members

Dr. Nymia Simbulan UPM

Dr. Eleanor Galvez PRC

Dr. Maria Ruth

Pineda-Cortel UST

Dr. Maricar Ching CEU

Ex-officio Dr. Josefina Tuazon UPM

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SIDE MEETINGS

Philippine Biomedical Devices and Innovations Consortium Meeting

A meeting with Dr. Deen and the members of PBDIC highlighted the importance of bringing engineers and clinicians together to come up with relevant biomedical devices and innovations.

In developing a technology, Dr. Deen shared the following points that university professors should consider:

• Ensure clear and deep understanding of the problems from the perspective of the users;

• Do not neglect ethical concerns. Inventors are liable for seeking ethical approval of the design;

• Non-scientific side of system design should be communicated with clinicians. Conduct activities outside the technical side of the study to ensure design is safe, efficient, and practical;

• Discuss with students patent disclosure. Encourage students to commercialize products; and

• Adequately acknowledge all the contributors or the co-authors of the technology.

The PBDIC members were requested to help in drafting the NUHRA 2017 – 2022 and help universities in developing engineering courses curricula with focus on biomedical devices. To bring together doctors and engineers, conduct of monthly webinars to facilitate exchange of ideas was recommended.

The President’s Report

APAME 2015

APAME in partnership with PAMJE, PCHRD, and UP Manila held APAME 2015 Convention at the Sofitel Philippine Plaza from 25-26 August 2015. With the theme “Advancing Access to Health Information and Publication: Shifting Paradigms, Trends and Innovations,” the convention was composed of 2 plenaries, 10 parallel sessions, and 5 workshop sessions. A total of 500 persons (316 participants, 45 speakers, 42 organizing committee members, and 97 partners) attended the convention.

Medical Writing Workshops

The 8th National Medical Writing Workshop and 1st Writeshop for Young Researchers was conducted in partnership with APAME, PAMJE, and PCHRD last 27-28 August 2015 at Sofitel Philippine Plaza with 39 participants and 4 PAMJE editor-facilitators.

The 9th National Medical Writing Workshop and 2nd Writeshop for Young Researchers was also conducted last 14-15 January 2016 at Widus Hotel, Clark, Pampanga with 36 participants and 4 PAMJE editor-facilitators.

PAMJE General Assembly

PAMJE members meet annually during the PCHRD Anniversary to report on the association’s year-end accomplishments and discuss the upcoming plans and activities.


AWARDING OF NEWLY ACCREDITED ETHICS REVIEW COMMITTEES (ERCS)

2016-Accredited ERCs for Level 3

• Asian Eye Institute Ethics Review Committee• Mary Mediatrix Medical Center Institutional Ethics

Review Board• Amang Rodriguez Memorial Medical Center Ethics

Review Board• Cardinal Santos Medical Center Research Ethics Review

Committee• Chinese General Hospital and Medical Center• East Avenue Medical Center Institutional Review Board• Jose R. Reyes Memorial Medical Center Institutional

Review Board• Manila Central University - Filemon D. Tanchoco

Medical Foundation Institutional Review Board• National Children's Hospital Institutional Review Board• San Juan de Dios Educational Foundation, Inc.

(Hospital) Institutional Review Board• University of Sto. Tomas Hospital – Institutional Review

Board• West Visayas State University Unified Biomedical

Research Ethics Review Committee• Western Visayas Medical Center Research Ethics

Review Committee• Cebu Doctor's University Hospital Research Ethics

Committee• Perpetual Succour Hospital Institutional Ethics Review

Board• Dr. Pablo O. Torre Memorial Hospital Research Ethics

Review Committee


Mariano Marcos State University Ethics Review Committee


• National Ethics Committee• University of Santo Tomas - College of Rehabilitation

Sciences Ethics Review Committee• St. Louis University Research Ethics Committee• Bicol Regional Training and Teaching Hospital Research

Review Committee• Western Mindanao State University Research Ethics

Oversight Committee• Metro Davao Medical & Research Center, Inc. -

Community Health & Development Cooperative Hospital Cluster Research Ethics Review Committee

• San Pedro Hospital Institutional Ethics Review Committee• Corazon Locsin Montelibano Memorial Regional Hospital

Research Ethics Review Committee

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