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Internet of Medical ThingsYury Rozenman, Qualcomm Life, Business Development

April 19th, 2016 / London, UK

//////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////Smart phone adoption is unprecedented2X faster than internet, 3X faster than social media

Sources: Pew Research, Ever Accelerating Rate of Technology Adoption, March 2014 Nielsen Telecom Research and Insights, Sept. 2011

50

40

30

20

10

0 1870 80 90 1900 10 20 30 40 50 60 70 80 90 2000 10 2014

Electricity (46)

Telephone (35)Radio (31)

Television (26)

PC (16)Mobile Phone (13)

The Web (7)

2014 Smart Phone (3 years)

// FIRST COMMERCIALLY AVAILABLE YEAR // // #

of y

ears

to

reac

h 25

% a

dopt

ion

in t

he U

S //

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Service Industries Over 20 Years…Then and Now…

To Mobile ShoppingMobile BankingMobile Reservations

From In-store ShoppingBanking TellerTravel Agents

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4

How Does Healthcare Compare?

Facility basedInconvenient

DelayedManual

DisconnectedEpisodic

Unaffordable

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PRIMARYCHRONIC DISEASE

COMPLEXCHRONIC DISEASE

$80B

Amateur Athletics

Consumer Fitness

Fitness/Exercise

Stress Management

Diabetes

Hypertension

Metabolic Syndrome

Trauma / Burn

Myocardial Infarction

Pulmonary Failure

Stroke

Surgery

Critical Care

$350BFITNESS

WELLNESS

$10B

$3000/day$300/day$3/day$0.30/day

Heart Failure

COPD

CAD

Cancer

Renal

MDD

ACUTECARE

Heart Failure

COPD

CAD

Cancer

Renal

MDD

HEAL

TH &

VITA

LITY

(CAK

E)DEATH

HHome Care Hospital Care

$3000/day$300/day$3/day$0.30/day

Spectrum of Care

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////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////Internet of Medical Things (IoMT) Connects…Home

Diagnostics Therapeutics Biometrics

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IoMT for Home Diagnostic, Pharma, and MedTechValue Based Care

• Pay for outcomes• Diagnostic + Therapeutic +

biometric documented outcome• Adherence and compliance• Reduce unnecessary

hospitalizations• Better, faster, cheaper clinical

trials

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INTEROPERABLE DEVICE DATA CAPTURE ON A COMMON PLATFORM

Patient EngagementCare CoordinationIntensive Monitoring

IoMT from Hosptial to Home and All Points Between

Point of Care Validation of Vitals

FDA Cleared Device & Sensors

Single Device Platform

Secure Pt. & Data Association

Unified Analytics & Alerting

Acute Hospital Sub-Acute: Clinic, Long TermCare, Skilled Nursing Facilities Home, Wellness, Wired & Wireless

Analytics Physical Alerts

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////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////“Mobilisation” of Clinical Trials (Lessons Learned)

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BYODMobile Devices Healthcare Device Connectivity

Mobile Operating Systems

Remote Device Management

MCD/HCD Testing & Validation

Mobile Broadband Service

Connectivity Standards

Mobile Operations

Relying on consumer’s own smartphone & tablet introduces many uncontrollable variables that need workaround processes. The first step is to understand the risk areas.

Understanding and being able to drive the mobile device landscape which is the endpoint that all these devices connect and drives the experience the patient has

Making previously disconnected healthcare devices wireless and making them interoperate well together

Wirelessly managing medical and mobile devices in the field with

upgrades and improvements without impacting patient experience

Mature processes and infrastructure to manage issues proactively before customers notice them and when customer-impacting issues occur, manage through them effectively

Leading the industry to work with medical device and mobile device industry to drive standards towards a more interoperable and seamless future

Managing and monitoring wireless carriers globally within an integrated experience to ensure a seamless experience with security, reliability and without data loss

Testing all the thousands of combinations of medical devices against thousands of combinations of each mobile make, model and OS version to ensure “it just works”

Managing the fragmentation of Android with IOS & Android rapid upgrade cycles within slower medical device cycles and meet medical device quality standardsUniquely driving the

mobile device world and the connected health world to enable both worlds to work together for the benefit of patients and trials

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Backup Examples

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Medtech Example: Remote Chronic Care Management

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• Create a frictionless solution to facilitate increased home testing for improved Warfarin therapy management

- Added convenience for patient- Informed interventions for provide- Reduce unnecessary hospitalizations and complications

resulting from sub-optimal Warfarin therapy management

- >500,000 patients on Roche Coaguchek today

Roche Diagnostics

“At its core, point-of-care diagnostics have a singular and elegant focus: to provide patients and their physicians with reliable, medically-relevant results when and where they need them.”1

1 Dr. Alan Wright, Chief Medical Officer, Roche Diagnostics

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AirView Care Management’s connected respiratory patient management platform, leverages the 2net and HealthyCircles Platforms

Dynamic tracking of respiratory rate, tidal volume, minute ventilation, usage

Aggregation and visualization of data for exception management

Wireless capture and transmission of custom Care Management checklist

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Clinical Trials

Pharma Example: Digital Medicines

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One pharma customer, millions of units in addressable market with common solution

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Heart Failure

Asthma• Same Breezhaler platform• 2018 Asthma drug

planned• >100M devices• 10-20M connected

• Entresto Heart Failure Drug• Companion diagnostic +

nurse monitoring service

• Trials of the future program

• >500k patients on Novartis trials at any time

• 100k new patients each year

Chief Executive Joe Jimenez said Thursday Novartis was “looking hard” at going to insurers with add-on services intended to further improve outcomes for patients on Entresto. He said this could involve providing a device that allowed doctors to monitor patients remotely so they could pick up on early signs of deterioration. “If you had a remote patient-monitoring device that the patient could use in their home together with Entresto, we could make an even more serious dent in hospitalization,” he said in an interview with The Wall Street Journal.

COPD• Breezhaler platform• 4 COPD drugs• >100M devices• 10-20M connected

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Walgreens Balance Rewards for healthy choices™ program integrated with 2net rewards patients for being engaged in their health care

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