powerpoint lecture slides prepared by janice meeking, mount … · 2019. 11. 4. · copyright ©...
TRANSCRIPT
![Page 1: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/1.jpg)
PowerPoint® Lecture Slides prepared by Janice Meeking, Mount Royal College
C H A P T E R
Copyright © 2010 Pearson Education, Inc.
6 Bones and Skeletal Tissues: Part A
![Page 2: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/2.jpg)
Copyright © 2010 Pearson Education, Inc.
Warm Up 11/2
• What is the difference between the axial and appendicular skeletons?!
• For fun… see how many bone names you can list under each branch without looking!
![Page 3: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/3.jpg)
Copyright © 2010 Pearson Education, Inc.
Skeletal Cartilages
• Contain no blood vessels or nerves
• Dense connective tissue girdle of perichondrium contains blood vessels for nutrient delivery to cartilage
![Page 4: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/4.jpg)
Copyright © 2010 Pearson Education, Inc.
Skeletal Cartilages
1. Hyaline cartilages • Provide support, flexibility, and resilience
• Most abundant type
2. Elastic cartilages • Similar to hyaline cartilages, but contain
elastic fibers
3. Fibrocartilages • Collagen fibers—have great tensile strength
![Page 5: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/5.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.1
Axial skeleton Appendicular skeleton
Hyaline cartilages Elastic cartilages Fibrocartilages
Cartilages
Bones of skeleton
Epiglottis Larynx
Trachea Cricoid cartilage Lung
Respiratory tube cartilages in neck and thorax
Thyroid cartilage Cartilage in
external ear Cartilages in nose
Articular Cartilage of a joint Costal cartilage
Cartilage in Intervertebral disc
Pubic symphysis
Articular cartilage of a joint
Meniscus (padlike cartilage in knee joint)
![Page 6: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/6.jpg)
Copyright © 2010 Pearson Education, Inc.
Growth of Cartilage
• Appositional
• Cells secrete matrix against the external face of existing cartilage
• Interstitial
• Chondrocytes divide and secrete new matrix, expanding cartilage from within
• Calcification of cartilage occurs during
• Normal bone growth
• Old age
![Page 7: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/7.jpg)
Copyright © 2010 Pearson Education, Inc.
Bones of the Skeleton
• Two main groups, by location
• Axial skeleton (brown)
• Appendicular skeleton (yellow)
![Page 8: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/8.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.1
Cartilage in external ear
Cartilages in nose
Articular Cartilage of a joint Costal cartilage
Cartilage in Intervertebral disc
Pubic symphysis
Articular cartilage of a joint
Meniscus (padlike cartilage in knee joint)
![Page 9: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/9.jpg)
Copyright © 2010 Pearson Education, Inc.
Classification of Bones by Shape
• Long bones
• Longer than they are wide
• Short bones
• Cube-shaped bones (in wrist and ankle)
• Sesamoid bones (within tendons, e.g., patella)
![Page 10: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/10.jpg)
Copyright © 2010 Pearson Education, Inc.
Classification of Bones by Shape
• Flat bones
• Thin, flat, slightly curved
• Irregular bones
• Complicated shapes
![Page 11: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/11.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.2
![Page 12: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/12.jpg)
Copyright © 2010 Pearson Education, Inc.
Functions of Bones
• Support
• For the body and soft organs
• Protection
• For brain, spinal cord, and vital organs
• Movement
• Levers for muscle action
![Page 13: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/13.jpg)
Copyright © 2010 Pearson Education, Inc.
Functions of Bones
• Storage
• Minerals (calcium and phosphorus) and growth factors
• Blood cell formation (hematopoiesis) in marrow cavities
• Triglyceride (energy) storage in bone cavities
![Page 14: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/14.jpg)
Copyright © 2010 Pearson Education, Inc.
Bone Markings
• Bulges, depressions, and holes serve as
• Sites of attachment for muscles, ligaments, and tendons
• Joint surfaces
• Conduits for blood vessels and nerves
![Page 15: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/15.jpg)
Copyright © 2010 Pearson Education, Inc.
Bone Markings: Projections
• Sites of muscle and ligament attachment • Tuberosity—rounded projection
• Crest—narrow, prominent ridge
• Trochanter—large, blunt, irregular surface
• Line—narrow ridge of bone
• Tubercle—small rounded projection
• Epicondyle—raised area above a condyle
• Spine—sharp, slender projection
• Process—any bony prominence
![Page 16: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/16.jpg)
Copyright © 2010 Pearson Education, Inc. Table 6.1
![Page 17: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/17.jpg)
Copyright © 2010 Pearson Education, Inc.
Bone Markings: Projections
• Projections that help to form joints • Head
• Bony expansion carried on a narrow neck
• Facet
• Smooth, nearly flat articular surface
• Condyle
• Rounded articular projection
• Ramus
• Armlike bar
![Page 18: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/18.jpg)
Copyright © 2010 Pearson Education, Inc. Table 6.1
![Page 19: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/19.jpg)
Copyright © 2010 Pearson Education, Inc.
Bone Markings: Depressions and Openings
• Meatus
• Canal-like passageway
• Sinus
• Cavity within a bone
• Fossa
• Shallow, basinlike depression
• Groove
• Furrow
• Fissure
• Narrow, slitlike opening
• Foramen
• Round or oval opening through a bone
![Page 20: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/20.jpg)
Copyright © 2010 Pearson Education, Inc. Table 6.1
![Page 21: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/21.jpg)
Copyright © 2010 Pearson Education, Inc.
Warm Up à
• What are the functional purposes of projections, depressions and holes on and within bones?
• à Pass up your BONE WRITING ASSIGNMENT!
![Page 22: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/22.jpg)
Copyright © 2010 Pearson Education, Inc.
Bone Textures
• Compact bone
• Dense outer layer
• Spongy (cancellous) bone
• Honeycomb of trabeculae
![Page 23: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/23.jpg)
Copyright © 2010 Pearson Education, Inc.
Structure of a Long Bone
• Diaphysis (shaft)
• Compact bone collar surrounds medullary (marrow) cavity
• Medullary cavity in adults contains fat (yellow marrow)
![Page 24: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/24.jpg)
Copyright © 2010 Pearson Education, Inc.
Structure of a Long Bone
• Epiphyses
• Expanded ends
• Spongy bone interior
• Epiphyseal line (remnant of growth plate)
• Articular (hyaline) cartilage on joint surfaces
![Page 25: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/25.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.3a-b
Proximal epiphysis
(b)
(a)
Epiphyseal line
Articular cartilage
Periosteum
Spongy bone
Compact bone
Medullary cavity (lined
by endosteum)
Compact bone
Diaphysis
Distal epiphysis
![Page 26: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/26.jpg)
Copyright © 2010 Pearson Education, Inc.
Membranes of Bone
• Periosteum
• Outer fibrous layer
• Inner osteogenic layer
• Osteoblasts (bone-forming cells)
• Osteoclasts (bone-destroying cells)
• Osteogenic cells (stem cells)
• Nerve fibers, nutrient blood vessels, and lymphatic vessels enter the bone via nutrient foramina
• Secured to underlying bone by Sharpey’s fibers
![Page 27: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/27.jpg)
Copyright © 2010 Pearson Education, Inc.
Membranes of Bone
• Endosteum
• Delicate membrane on internal surfaces of bone
• Also contains osteoblasts and osteoclasts
![Page 28: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/28.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.3c
(c)
Yellow bone marrow
Endosteum
Compact bone
Periosteum
Perforating (Sharpey’s) fibers
Nutrient arteries
![Page 29: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/29.jpg)
Copyright © 2010 Pearson Education, Inc.
Structure of Short, Irregular, and Flat Bones
• Periosteum-covered compact bone on the outside
• Endosteum-covered spongy bone within
• Spongy bone called diploë in flat bones
• Bone marrow between the trabeculae
![Page 30: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/30.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.5
Compact bone
Trabeculae
Spongy bone (diploë)
![Page 31: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/31.jpg)
Copyright © 2010 Pearson Education, Inc.
Location of Hematopoietic Tissue (Red Marrow) • Red marrow cavities of adults
• Trabecular cavities of the heads of the femur and humerus
• Trabecular cavities of the diploë of flat bones
• Red marrow of newborn infants
• Medullary cavities and all spaces in spongy bone
![Page 32: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/32.jpg)
Copyright © 2010 Pearson Education, Inc.
Microscopic Anatomy of Bone
• Cells of bones
• Osteogenic (osteoprogenitor) cells
• Stem cells in periosteum and endosteum that give rise to osteoblasts
• Osteoblasts
• Bone-forming cells
![Page 33: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/33.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.4a-b
(a) Osteogenic cell (b) Osteoblast
Stem cell Matrix-synthesizing cell responsible for bone growth
![Page 34: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/34.jpg)
Copyright © 2010 Pearson Education, Inc.
Microscopic Anatomy of Bone
• Cells of bone
• Osteocytes
• Mature bone cells
• Osteoclasts
• Cells that break down (resorb) bone matrix
![Page 35: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/35.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.4c-d
(c) Osteocyte
Mature bone cell that maintains the
bone matrix
(d) Osteoclast
Bone-resorbing cell
![Page 36: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/36.jpg)
Copyright © 2010 Pearson Education, Inc.
Microscopic Anatomy of Bone: Compact Bone • Haversian system, or osteon—structural unit
• Lamellae
• Weight-bearing
• Column-like matrix tubes
• Central (Haversian) canal
• Contains blood vessels and nerves
![Page 37: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/37.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.6
Structures in the central canal
Artery with capillaries Vein Nerve fiber
Lamellae
Collagen fibers run in different directions
Twisting force
![Page 38: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/38.jpg)
Copyright © 2010 Pearson Education, Inc.
Microscopic Anatomy of Bone: Compact Bone • Perforating (Volkmann’s) canals
• At right angles to the central canal
• Connects blood vessels and nerves of the periosteum and central canal
• Lacunae—small cavities that contain osteocytes
• Canaliculi—hairlike canals that connect lacunae to each other and the central canal
![Page 39: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/39.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.7a-c
Endosteum lining bony canals and covering trabeculae
Perforating (Volkmann’s) canal
Perforating (Sharpey’s) fibers
Periosteal blood vessel Periosteum
Lacuna (with osteocyte)
(a)
(b) (c)
Lacunae
Lamellae
Nerve Vein Artery
Canaliculi Osteocyte in a lacuna
Circumferential lamellae
Osteon (Haversian system)
Central (Haversian) canal
Central canal
Interstitial lamellae
Lamellae
Compact bone
Spongy bone
![Page 40: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/40.jpg)
Copyright © 2010 Pearson Education, Inc.
Microscopic Anatomy of Bone: Spongy Bone • Trabeculae
• Align along lines of stress
• No osteons
• Contain irregularly arranged lamellae, osteocytes, and canaliculi
• Capillaries in endosteum supply nutrients
![Page 41: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/41.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 6.3b
(b)
Lacunae
Lamellae
Nerve
Vein
Artery
Canaliculus
Osteocyte in a lacuna
Central canal
![Page 42: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/42.jpg)
Copyright © 2010 Pearson Education, Inc.
Chemical Composition of Bone: Organic
• Osteogenic cells, osteoblasts, osteocytes, osteoclasts
• Osteoid—organic bone matrix secreted by osteoblasts
• Ground substance (proteoglycans, glycoproteins)
• Collagen fibers
• Provide tensile strength and flexibility
![Page 43: PowerPoint Lecture Slides prepared by Janice Meeking, Mount … · 2019. 11. 4. · Copyright © 2010 Pearson Education, Inc. Chemical Composition of Bone: Inorganic • Hydroxyapatites](https://reader036.vdocument.in/reader036/viewer/2022071510/612f09551ecc515869433027/html5/thumbnails/43.jpg)
Copyright © 2010 Pearson Education, Inc.
Chemical Composition of Bone: Inorganic
• Hydroxyapatites (mineral salts)
• 65% of bone by mass
• Mainly calcium phosphate crystals
• Responsible for hardness and resistance to compression