powerpoint presentation · 2. positive test for aqp4-lgg using best available detection method...
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(Optic Neuritis Study, 2008)
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(Beck, Cleary, & Backlund, 1994)
(Fang, Lin, & Donahue, 1999)
(Optic Neuritis Study, 2008)
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(Optic Neuritis Study, 2008)
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Day 22 Day 24 Day 26 Day 28 Day 30 Day 32 Day 34
NVAcc: 20/400 20/400 20/200 20/200 20/200+1 20/50+1 20/20-2
Color: <50% 50% 50% 50% 80% 12/15 CP 14/16 CP
EOM: Full Full Full - - - -
Plasmapheresis
session*:
1 2 3 4 - - -
Prednisone: 60mg 60mg
60mg
60mg
60mg
60mg
60mg
*5th session cancelled (low fibrinogen/bleeding)
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(Weinshenker & Wingerchuk, 2014)
(Spadaro et al., 2015)
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(Wingerchuk et al., 2015)
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(Wingerchuk, Lennon, Pittock, Lucchinetti, &
Weinshenker, 2006)
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(Wingerchuk et al., 2015)
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Anti-AQP4 Assays
60-80% sensitive
>= 97% specific
Generally worse than MS
- 50% will be blind in ≥ 1 eye at 5 years
(Waters et al., 2012)
(Wingerchuk et al., 2015)
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(Bizzoco et al., 2009)
(Marrie & Gryba, 2013)
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(Kimbrough et al., 2012)
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(Kimbrough et al., 2012)
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