pre-feasibility report for proposed api...
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Pre-Feasibility Report of
Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
PRE-FEASIBILITY REPORT
FOR
PROPOSED API INTERMEDIATE
MANUFACTURING
OF
GALAXY LABORATORIES
PRIVATE LIMITED
At
Plot No. B-10, MIDC Newasa Industrial Area, at Post Tukai – Shingve, Auranagabad –
Pune Highway, Near Godegaon, Tal. Newasa, Ahmednagar – 414607 (Maharashtra)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 1
EXECUTIVE SUMMARY
Galaxy Laboratories is a venture capital company promoted with equity participation from
Industrial Development Bank of India (IDBI) in the year 1995.
The company is a manufacturer of Intermediates for API’s (Active Pharmaceutical
Ingredients) and specialty Agro Chemicals.
Galaxy is one of the leading manufacturers of the product Furfurylamine in the world.
Furfurylamine is used in an API known as Furosemide which is primarily used for the
treatment of hypertension, congestive heart failure and edema.
Besides the domestic API’s intermediates and Agro Chemicals market, it has a foreign
customer base in Belgium, Germany, Israel, Japan, Italy and Korea. It has created a name
for itself in the area of Catalytic Hydrogenation and Fractional Distillation.
One of existing manufacturing facility is located at Railway Station MIDC Aurangabad,
Maharashtra. The land area is 8158 sq. meters and the company has put up excellent
manufacturing facilities as per international standards and complies with the prevailing GMP
norms of MNC’s. The turnover of the financial year 2013-14 was 29 Crores. The
manufacturing Facilities are Multipurpose and versatile to handle advance technologies for
manufacturing API Intermediates and specialized Agro Chemicals.
NAME OF THE PROMOTERS AND THEIR TRACK RECORD :
Sr.
No
.
Name Age
(yrs)
Total
Experience
Educational
Qualifications
Experience in Brief
1. Shrikant
Deshmukh
60 36 years B Tech.
(Pharmaceuticals
& Fine
Chemicals),
UDCT, Mumbai.
Worked with multinational
companies’ viz. Hoechst
(Sanofi - Aventis), Roche
Products Ltd., and
Boehringer-Knoll at
various levels.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Prior to Galaxy
Laboratories, co-
promoter of Ariane
Orgachem Pvt. Ltd. (Now
AMRI India Ltd.) engaged
in manufacturing of APIs.
2. Nagesh
Walimbe
60 36 years Chemical
Engineer from
Indian Institute of
Technology ,
Mumbai (I.I.T.)
He has worked with
Multinational Companies
namely Hoechst India
Limited, Gharda
Chemicals Ltd, Lupin
Laboratories & Standard
Organics Ltd in varied
Capacities at Design &
Management levels in
India and abroad. He is
running his own
consultancy firm namely
Zen Chemiconsultech
Pvt. Ltd., Hyderabad.
Galalxy is proposing new unit at Newasa MIDC with latest technology as per the GMP for
producing the critical intermediates for API, Agro Products and Specialty Chemicals.
The products are Hydrogen Gas, Furfuraldehyde, Furfuryl Alcohol, Mono IsoPropyl Amine,
Di Methyl Amine Hydrochloride, Furfurylamine, 6-Chloro-5(2,3 Dichlorophenoxy) -2-
Methylthio 1H , Benzimidazole (Triclabendazole Crude), 5-Chloro-4-Amino-2,1,3-
Benzothiadiazole (TNZ), 2-Furoic Acid, Cyclohexenyl Ethyl Amine (CHEA).
The company is also putting up Agro Research Centre herewith well-equipped and designed
Research & Development Laboratory for API Intermediates.
The proposed project comes under 5(f) of the schedule in EIA notification 2006. Thus
environmental clearance is required for the said project. Particulars and details about the
proposed project are given in following table
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Particulars Details
Name of the project
Proposed API Intermediate
manufacturing unit at Plot No. B10,
MIDC Newasa industrial area At Post.
Tukai - Shingve, Taluka. Newasa Dist.
Ahmednagar.
Site B-10, Tukai-Shingve,Tal. Newasa, Dist.
Ahmednagar
Area 48400 sqm
Water requirement 84 m3/day
Power requirement 320 KVA
Fuel requirement 750 TPA
DG Set 320 KVA
Man Power 350
Project cost 1430 Lacs
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 2
INTRODUCTION OF THE PROJECT
2.1 IDENTIFICATION OF PROJECT AND PROJECT PROPONENT
Galaxy Laboratories Private Limited an API Intermediate manufacturing unit is proposed at
Newasa MIDC on Pune- Aurangabad highway in Maharashtra. The company is a
manufacturer of Intermediates for API’s (Active Pharmaceutical Ingredients) and Specialty
Agro Chemicals.
PROPOSED PRODUCTS
The proposed Unit at Newasa is comprised of manufacturing 10 different products. The
details of products and the reasons for manufacturing are given in Table No 2.1.
Table No2.1
Sr.
No
Product Name CAS No. Capacity (per
annum)
Reason for identification/ End
use of Product
1 Hydrogen Gas 1333-74-0 18.72 Lacs
NM3
(250 NM3/Hr)
• Key raw material for
pharmaceutical, chemical,
agricultural, food, and allied
industries.
• Used increasingly for its property
of making the chemical
processes pollution free.
2 Furfuraldehyde 98-01-1 600 Tons • Key raw material in
manufacturing of Furfurylamine
and Furfuryl alcohol and 2-Furoic
Acid.
• The main outlet of furfural is that
it is a unique chemical feed stock
for other furan derivatives.
• Furfural is effective as a solvent
in phenolic resins and a wetting
agent. In the manufacture of
abrasive wheels, brake linings,
and refractory products for steel
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
industry.
• Refining of lubrication oils and
decolorizing agent (Oil Industry).
3 Furfuryl Alcohol 98-00-0 360 Tons • Chemical building block for drug
synthesis.
• Furfuryl alcohol plays a vital role
in the production of foundry sand
binders.
• It is extensively used to produce
cores and molds for metal
casting.
• Wood modification.
• Corrosion resistant for cement,
mortars and fiber-reinforced
plastics.
4 Mono Iso
Propyl Amine
75-31-0 120 Tons • Glyphosate herbicide
formulations.
• Regulating agent for plastic.
• Intermediate in organic synthesis
of coating materials, plastics,
pesticides, rubber chemicals,
pharmaceuticals and others.
• Used an additive in petroleum
industry.
5 Di Methyl
Amine
Hydrochloride
506-59-2 1200 Tons � Di Methyl Amine Hydrochloride
is used in an API drug named
Metformin. Metformin is an oral
andiabetic drug.
� Metformin works by suppressing
glucose production by the liver.
6 Furfurylamine 617-89-0 240 Tons • Used as a key raw material for
Furosemide (API Drug), this is
primarily used for the treatment
of hypertension, kidney stone,
congestive heart failure and
edema.
• It has a new application in agro
products.
7 6-Chloro-5(2,3 68786-66- 100 Tons � Triclabendazole (N-1) is used
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Dichlorophenox
y)-2-Methylthio
1H
Benzimidazole
(Triclabendazol
e Crude)
3 in a drug named
Triclabendazole which is
developed as an oral route
drug, and displays high
efficacy against both
immature and adult liver
flukes, roundworms and
ectoparasites.
� It is also used as a veterinary
drug.
8 5-Chloro-4-
Amino-2,1,3-
Benzothiadiazol
e (TNZ)
30536-19-
7
24 Tons • 5-Chloro-4-Amino-2,1,3-Benzothiadiazole is used in an API drug called Tizanidine, which is a short-acting muscle relaxant. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.
9 2-Furoic Acid 29447-28-
9
60 Tons • 2-Furoic acid helps sterilize
and pasteurize many foods.
• 2-Furoic acid is used as an
intermediate in a drug named
Quinfamide. Quinfamide is a
drug that has anit-parasitic
properties. It is used to treat
chronic and sub-acute intestinal
amebiasis.
• 2-Furoic Acid is used as
speciality chemical in allied
industries.
10 Cyclohexenyl
Ethyl Amine
(CHEA)
3399-73-3 120 Tons • CHEA is used as an
intermediate for the drug named
dextromethorphan which is used
for treating cough.
PROJECT PROPONENT
Galaxy Laboratories is a venture capital company promoted with equity participation from
Industrial Development Bank of India (IDBI) in the year 1995. The company is a
manufacturer of Intermediates for API’s (Active Pharmaceutical Ingredients) and specialty
Agro Chemicals. It is one of the leading manufacturers of the product Furfurylamine in the
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
world. Furfurylamine is used in an API known as Furosemide which is primarily used for the
treatment of hypertension, congestive heart failure and edema.
Galaxy promoted by Shrikant Deshmukh and Nagesh Walimbe both are having 36 years of
experience in chemical units worked with multinational companies. Hoechst India Ltd.,
Roche products Ltd. etc.
2.2 BRIEF DESCRIPTION OF NATURE OF THE PROJECT
The proposed Unit at Newasa aims at commercialization of ingeniously developed
technology from Agro based in the area of Furfural chemistry and value-added derivatives of
Furfural namely Furfuryl Alcohol and Furfurylamine. Galaxy has also proposed commercial
processes for API Intermediates. These technologies are mainly in the area of reductive
Amination by hydrogenation, catalytic hydrogenation with selectivity and isomerization.
The company is also setting up a Hydrogen Plant for the generation of in-house hydrogen
gas. Further, the company is adept at handling Hydrogen gas, Raney Nickel, Palladium-
Carbon, Platinum and other noble metal catalysts, as also in hazardous chemicals like
Carbon Di Sulphide, Fuming Nitric Acid, Thionyl Chloride, Phosphorous Oxychloride, Liquid
Ammonia etc.
2.3 NEED FOR THE PROJECT AND ITS IMPORTANCE TO THE COUNTRY
OR REGION
The products proposed to be manufactured by the company are a new generation product
range based on Reductive Amination by Hydrogenation, these are high value intermediates
involving Hydrogenation Technology and compounds require Ring Hydrogenation for the
manufacture lifesaving API’s.
The products developed by Galaxy are substantially of low prize compared to imported
material. This is due to much less consumption of Raw Materials, Less number of Chemical
steps involved in Manufacturing & being Green Technology.
Products viz 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole
(Triclabendazole Crude), 5-Chloro-4-Amino-2,1,3- Benzothiadiazole, 2-Furoic Acid proposed
to manufactured in the project have huge export potential and contribute highly in import
substitution for the country.
Hydrogen gas manufacturing will reduce import of hydrogen gas from China and Germany.
At present procurement of hydrogen gas is been done from outside of Maharashtra for our
Aurangabad plant. Due to establishment of Indian made hydrogen plant with M/s Muse
Consultants & Multifab Engineers (Mumbai) will be the first of its kind to be set up in
Newasa. Hydrogen gas will be available for captive consumption and also support/supply
other industries which have requirement for the same. Through this venture, India can
establish its name in the foreign market.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Manufacturing of Furfuraldehyde, furfural alcohol and furfuryl amine in India will considerably
reduce imports from International markets. The country will be self reliant and also reducing
dependability of Indian API and allied manufacturers on International market. Hence the
outflow of foreign exchange will be limited.
Galaxy is the only company who has successfully introduced Furfurylamine in India and has
become one of world’s largest manufacturer. Recent research has developed some high
value agro-products using 3-Hydroxy Pyridine and 2-Chloro-3-Hydroxy Pyridine as basic raw
materials. These two products are synthesized from Furfurylamine; therefore demand for
Furfurylamine is growing disproportionately.
Production of Mono Iso Propyl Amine (MIPA), Di Methyl Amine Hydrochloride (DMA.Hcl),
Cyclohexenyl Ethyl Amine (CHEA) will be profitable due to high tonnage production and no
dependability on petroleum products and in-house availability of hydrogen gas. These API
intermediates have very high potential because API’s made out of the intermediates have
come out of patent regulations in the international market since 2009. Therefore, Indian
MNC’s are launching these API’s, as a result, consumption of these intermediates have
increased rapidly.
Thus the setting up of proposed API unit at Newasa will contribute in economic growth of
India as well as region by increasing exports and limiting imports of material / chemicals. At
the same raising self reliance of the country on these products.
2.4 DEMAND-SUPPLY GAP
Demand-Supply Gap for Furfuraldehyde, Furfuryl Alcohol and Furfurylamine,
Hydrogen gas
The information given for the three products mentioned below is related to World Demand-
Supply gap.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Furfuraldehyde
Furfuryl Alcohol
53%
13%4%
4%
3%
5%
2%8%
6% 2%
World Demand for
Furfuryl Alcohol
(TPA)
China
USA
India
52%34%
9%5%
World Supply for
Furfuryl Alcohol
(TPA)
China
Thailand
USA
India
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Furfurylamine
Hydrogen Gas
Hydrogen gas will not be exported. There is a huge demand for Hydrogen gas in the domestic
market and Galaxy will majorly consume it captively.
The below mentioned information is based on demand-supply gap for Hydrogen Gas in
domestic market (India).
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Mono Iso Propyl Amine (MIPA)
For explaining the demand-supply gap, export demand has not been taken into consideration,
as the entire capacity is already being required by our current customers.
Supply:
Sources majorly imported
• Manufactured in India in unorganized sector
Di Methyl Amine Hydrochloride (DMA.HCl)
Supply
• Imported from China
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
• Small Manufacturers
• In-house production by API Companies
Cyclohexenyl Ethyl Amine (CHEA)
Supply
• Imported from China
• Small Manufacturers in India
6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole Crude)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Supply
• Imported from China
• Small Manufacturers in India
• Currently the major supplier is Galaxy for domestic market.
•
5-Chloro-4-Amino-2,1,3- Benzothiadiazole (TNZ)
38%
14%
28%
10%
10%
Demand for TNZ (TPA)
Dr. Reddy's
Laboratories
(Hyderabad)
Med Concepta
Sun Pharma
(Baroda)
2-Furioc Acid
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
2.5 IMPORTS VS. INDIGENOUS PRODUCTION
SR.
NO.
PRODUCT IMPORT INDIGENOUS
1 Hydrogen Gas
(Hydrogen Plant)
Currently hydrogen plant is
imported from Germany or
China.
Galaxy along with Muse
Consultants is venturing into
setting up the first Indian made
Hydrogen plant.
This will give the country prestige
and importance to erect further
more hydrogen plants in the near
future at a low cost compared to
that of the foreign countries.
2 Furfuraldehyde The current unorganized
sectors of manufacturers in
India are not able to fulfill the
requirement of Furfural.
Lot of Furfural is required to
produce Furfural related
derivatives and therefore it is
imported from China &
Thailand.
Galaxy plans to make tie ups with
farmers producing corn, in and
around Newasa area and will
produce Furfural in huge quantity
for meeting the requirements of
manufacturers who focus on value
added derivatives of Furfural.
3 Furfuryl Alcohol Furfuryl Alcohol is currently
manufactured mostly in China.
As this is an important chemical
for many industries other than
Pharmaceuticals, manufacturing in
India will open a new export
market and will meet indigenous
requirement.
4 Mono Iso Propyl Amine Currently MIPA is being
imported in India by companies
like IPCA Laboratories Pvt. Ltd.
Indigenous production of MIPA will
promote exports and is helpful to
many industries as it has multiple
properties and used in varied
industries.
5 Di methyl amine
hydrochloride
Di methyl amine is being
imported in India from China.
This is used as an important raw
material for manufacturing an
important API drug known as
Metformin. Indigenous
manufacturing of this drug will help
Indian based API MNC’S in
sourcing this raw material from
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Galaxy rather than importing it.
6 Furfurylamine Other than Galaxy there is only
one company called PENN
Specialty in the U.S.A. that
manufacture Furfurylamine.
Galaxy is the only manufacturer in
India that manufactures Furfuryl-
amine and supplies it to API
companies like IPCA Laboratories,
Amri India, Hemdeep and Sri
Krishna Laboratories.
This material is also exported to
Sanofi Aventis (Germany), Teva
Tech (Israel), Syngenta (USA),
and Sojitz (Japan).
7 6-Chloro-5(2,3
Dichlorophenoxy)-2-
Methylthio 1H
Benzimidazole
(Triclabendazole
Crude)
These raw materials were
imported from South East
Asian countries like China,
Thailand etc.
Galaxy Supplies these key raw
materials to company’s like:
• NGL Pharma Laboratories
• Sequent Scientific Ltd.
• Dr. Reddy’s Laboratories
• Sun Pharma
• Med Concepta
• Survival Technologies
• Wokhardt Limited
Galaxy has facilitated the supplies
of these MNC’s to provide key raw
materials for API drugs.
8 5-Chloro-4-Amino-
2,1,3- Benzothiadiazole
9 2-Furoic Acid
10 Cyclohexenyl Ethyl
Amine (CHEA)
2.6 EXPORT POSSIBILITY
All the products have potential of being exported as there has been a very niche
segment of manufacturers in India that manufacture these above mentioned molecules
and Galaxy’s share in the supply is a major one. These products are in high demand for
API MNC’S established in India and abroad.
Galaxy has established its name in the API Intermediate market and has been an
approved vendor for many MNC’S . When developing a new product, the company can
leverage the brand to market the products and can sell these products in the export
market.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
2.7 DOMESTIC/EXPORT MARKETS
Already discussed in section 2.5 and 2.6
2.8 EMPLOYMENT GENERATION (DIRECT/INDIRECT) DUE TO THE PROJECT
The local areas will be benefited by way of generation of employment opportunities, increased
demand for local products and services. There will be an overall improvement in the income
level of the people.
The project creates employment to about 350 persons once the plant comes to the operational
stage and for 150 persons during construction stage. Top priority will be given to locals for
semi-skilled and unskilled jobs. With the development of this plant there will be a lot of scope
for more ancillary development, which in turn will benefit the nation.
There will be a certain enhancement of educational and medical standards of people in the
study area. There will be generally positive and beneficial impacts by way of economic
improvements, transportation, aesthetic environment and business generation. There will be an
overall upliftment of socio-economic status of the people in the area with the implementation of
the project.
Manufacturing of furfural requires corncobs in high tonnage which can be achieved by providing
the local farmers with seeds which will directly benefit the farmers in terms of agriculture and
the company for meeting its raw material needs. Biomass generated in this product is of good
fuel value and can be directly used as boiler fuel.
Agriculture – Cooperative Society will be formed, wherein the farmers will be benefited and
there will be growth in agriculture.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 3
PROJECT DESCRIPTION
3.1 TYPE OF PROJECT INCLUDING INTERLINKED AND INTERDEPENDENT
PROJECTS
3.1.1 Type of Project
Galaxy Laboratories Private Limited is mainly engaged in manufacturing of API
Intermediates and Agro-Chemicals. The company in the proposed project aims at
commercialization of indigenously developed technology from Agro based in the area of
Furfural chemistry and value-added derivatives of Furfural namely Furfuryl Alcohol and
Furfurylamine. The company is setting up a Hydrogen Plant for the generation of in-
house hydrogen gas.
3.1.2 Interlinked and Interdependent Projects
One of the products Furfuraldehyde requires agro waste (corncob) as raw material.
Galaxy aims at making tie-ups with farmers in proximity with the Newasa for the
cultivation of corn. This will benefit the farmers as corn cultivation is pre-dominant in
Aurangabad district. Thus, the farmers and the company will be interdependent and will
benefited.
The Hydrogen plant being set-up at Newasa is the first Indian made Hydrogen plant.
Which is a raw material for Furfuryl alcohol, Furfuryl amine, CEA, CAB,MIA,
3.2 Location
The proposed chemical plant is located Plot No. B-10, MIDC Newasa Industrial Area, at
Post Tukai – Shingve, Auranagabad – Pune Highway, Near Godegaon, Tal.Newasa,
Ahmednagar – 414607 (Maharashtra). The latitude and longitude are 19018’20.12’’N ,
74051’18.38’’ to 19018’23.36’’ N, 74051’09.69’’E respectively.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Fig 3.1 Google image of Location
3.3 DETAILS OF ALTERNATE SITES CONSIDERED AND THE BASIS OF SELECTING
THE PROPOSED SITE:
3.3.1 Alternate Sites
API intermediate unit can be set-up in industrial areas and therefore four MIDC namely,
Waluj, Chikhalthana, Railway Station and Paithan could be considered. However,
comparatively the land that Newasa MIDC had an advantage in terms of location and well
developed infrastructure, close to State Highway.
The Newasa MIDC land is economical as compared to MIDC land available at the other sites
and as the project requires abundant land area, the Newasa MIDC land was preferred.
3.3.2 Selection of the Proposed Site
The project is being proposed to set-up at MIDC Newasa Industrial Area, as the location is
an industrial land under the authority of Maharashtra Industrial Development Corporation
(MIDC); it facilitates all statutory clearances required for running manufacturing companies
as compared to free hold land.
Newasa MIDC is not situated within the city limits, which was an advantage as no residential
area is in proximity and thus will not be affected by the ancillary effects of the manufacturing
unit. (For e.g. Noise, odor etc)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
The land is situated in the “D-Zone” of the development sector and the unit is entitled to
subsidiaries like power, interest cost, and sales tax.
Newasa Industrial area is in the vicinity of Taluka places namely, Kanad, Sillod, Soyagaon,
Vaijapur and Phulambri. Corns are extensively cultivated in all these areas, this will greatly
facilitate the procurement of corn cobs due to easy availability and cheaper transportation
costs.
The product Furfural can also be produced from bagasse as the main raw material. Bagasse
is abundantly available in Newasa region and is in vicinity to the company’s site in Newasa
owing to number of sugar factories located nearby.
3.4 SIZE OR MAGNITUDE OF OPERATION:
The proposed project will be set-up on 48400 sq.mtr (over 12 Acres) land at Newasa MIDC.
The facility will have a manufacturing plant with state of the art technology. The company is
also putting up agro research centre at the site with well-equipped and designed research
and development laboratory for API Intermediate.
The company has high consciousness for environmental protection and has established an
Effluent Treatment Plant for treating any type of chemical effluent.
Sr. No PRODUCT CAPACITY
1 Hydrogen Gas 18.72 Lacs NM3
2 Furfuraldehyde 600 Tons
3 Furfuryl Alcohol 360 Tons
4 Mono Iso Propyl Amine 120 Tons
5 Di Methyl Amine Hydrochloride 1200 Tons
6 Furfurylamine 240 Tons
7 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H
Benzimidazole (Triclabendazole Crude)
100 Tons
8 5-Chloro-4-Amino-2,1,3- Benzothiadiazole 24 Tons
9 2-Furoic Acid 60 Tons
10 Cyclohexenyl Ethyl Amine (CHEA) 120 Tons
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
3.5 PROJECT DESCRIPTION WITH PROCESS DETAILS
A) Hydrogen Gas from Methanol Cracking
• Galaxy Laboratories Private Limited (Newasa) is the first company, along with M/S.
Muse Consultants & Multifab Engineers (Mumbai) to set up the first Indian made
Hydrogen Plant.
• The Hydrogen Plant will work on the technology of producing hydrogen gas from
methanol cracking.
Technical Details
The basic reaction of methanol decomposition/ reforming comprises of two parts:
CH3OH + H2O = CO2 + 3H2
Heat of Reaction = - 49.5 kJ/mol
The basic process of methanol decomposition consists of the following steps:
• Mixing of methanol and Demineralized water (D.M. Water). • Preheating and evaporation of the methanol/water mixture. • Methanol decomposition and shift conversion. • Process gas cooling and condensate separation. • Purification in PSA unit. (The hydrogen is purified in a PSA unit operating with a
hydrogen recovery rate of approx. 75% - 80 %.)
Route of Synthesis for Hydrogen Gas
+
Methanol Water Hydrogen Gas Carbon di Oxide
(MW-32) (MW-18) (MW-2) (MW- 44)
H—H
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
FLOW CHART FOR HYDROGEN GAS MANUFACTURING
Batch Tank Compressor
Pre-heater Separator Condenser
i) Methanol (1180 TPA)
ii) D.M.Water (675 TPA)
Evaporator
Reactor Filled
with Catalyst
(Stationary Bed
at 2800C)
Recovered Methanol + Water
(Recycled to Batch Time and to
Evaporator)
Cooling with
Cooling Water
Vent Gases (55-88% CO2 + 0-2% CO + 40% H2) v/v
14.22 Lacs NM3/Annum at 190 NM3/Hr
(Vent Gases are vented at 11 meter height with flame
arrester at the top)
PSA
Section
Seal Pot
H2
Purging
vessel
Hydrogen Purification Unit
Hydrogen Gas (Purity 99.99%)
Storage in MS cylinder having capacity 5.7 NM3 per cylinder at 150 Kg/cm2
(18.72 Lacs NM3/Annum at 250 NM
3/Hr)
Heating with Thermopac
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
B) Furfuraldehyde (Furfural)
• Furfuraldehyde is an organic compound derived from a variety of agricultural
products such as corn cobs, oat, wheat bran and sawdust.
• The process of furfural includes hydrolysis of pentosan, which is present in
the above mentioned agricultural products.
• Galaxy is currently aiming at producing furfural from corn cobs using sulphur
trioxide and steam at high temperature.
• The R & D of Galaxy Laboratories Private Limited is in the process of
developing seeds for corn cobs with high pentosan content.
• The company has filed a patent for “A Process for Preparing Furfural”. (Copy
of Patent Novelty Search Report is enclosed)
Technical Details
Corn cobs are cut into 3 to 6 mm size and subjected to vapor phase hydrolysis using sulphur
trioxide gas and steam at elevated temperature and pressures in cylindrical vessel. The
process generates formation of Furfural along with other chemicals. The Furfural thus
generated is then taken out of the cylindrical vessel by using dry steam under pressure and
these vapors are cooled and fractionated to obtain Furfural along with other by-products
namely Acetic Acid, Acetone and Methanol. By employing specific conditions of temperature,
pressure and relative concentrations of sulphur trioxide, 9 to 12% furfural yield is extracted.
Route of Synthesis for Furfuraldehyde
Pentosan Furfuraldehyde
(MW-150) (MW- 96.09)
Dilute H2SO4
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
FLOW CHART FOR FURFURAL MANUFACTURING
i) Corn Cobs
ii) Dilute H2SO4
Digester for
Corn Cobs Filter
Furfural
Crude &
Water
Distillation Unit
Spent Corn Cob To Boiler Feed
Caustic Lye
Top Layer
Bottom Layer
For Separation of Water
Layer for ETP
Reside sent to Hazardous
Waste Facility
Furfural Pure
(Output: 12 to 12.4 MT/ANNUM)
Pre-Feasibility Report of
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speciallity Agro chemicals (Newasa)
C) Furfuryl Alcohol
Furfural (Furfuraldehyde) is reacted with Hydrogen Gas in liquid phase using Raney Nickel
Catalyst to form Furfuryl Alcohol. By employing specific conditions of temperature, pressure
and relative concentrations of these three components, a high selectivity is achieved at
relatively low pressures of Hydrogen leading to over 95% yield.
Technical Details:
Stage I:
In an 1100 Liters Autoclave, charge specific quantity of Furfural and Raney Nickel Catalyst.
Close the autoclave and flush it with nitrogen to remove trapped air in the empty space of the
autoclave. Then flush the autoclave with Hydrogen to remove Nitrogen from the empty place.
Keep 0.5 Kg/cm2 hydrogen gas pressure in the autoclave and slowly heat the reaction mass in
the autoclave at 139 to 140ºC. The pressure in the autoclave will start rising. Keep very slow
purging of Hydrogen gas and maintain Hydrogen gas at 15 to 15.5 Kg/cm2 and temperature at
139 to 140ºC. Apply intermittent heating or cooling to maintain these conditions. After 15 hours
of reaction start drawing sample for GC analysis and check for conversion. At the end of 20 to
22 hours Furfuryl Alcohol conversion will reach to 95 to 96% level with 4.5 to 3.5% level
Unreacted Furfural and impurity level of 0.4 to 0.6%. Stop the reaction at this stage by applying
cooling, release hydrogen, flush the Autoclave with nitrogen and filter the batch to get crude
Furfuryl Alcohol.
Stage II:
Crude Furfuryl Alcohol obtained in the Stage I is taken in a distillation still and distilled under
vacuum (5mm of Hg) to recover Furfuryl Alcohol (99.5%) & Furfural (98.5%).
The company has filed a patent for “A Process for Preparing Furfuryl Alcohol”. (Copy of Patent
novelty search report is enclosed)
Route of Synthesis for Furfuryl Alcohol
+ +
Furfural Hydrogen Gas Furfuryl Alcohol
H—H
Nickel Catalyst
Tetrahydro Furfural
Alcohol
(MW-96.09) (MW-2) (MW-98.10) (MW-102.13)
Pre-Feasibility Report of
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FLOW CHART FOR FURFURAL ALCOHOL MANUFACTURING
i) Furfural Crude Liquid
ii) Nickel Catalyst
iii) Hydrogen Gas
Autoclave
20 to 25 Kg/cm2
90 to 95 ºC
High Vacuum
Fractional
Distillation System
Pressure Filter
Furfural Alcohol
Crude Transferred
to Distillation
Pure Furfuryl Alcohol
Residue sent to Hazardous Waste
Facility
(Output 7.2 to 7.6 MT/Annum)
Pre-Feasibility Report of
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D) Mono Iso Propyl Amine (MIPA)
Stage I
In a high pressure Autoclave charge acetone, Liquor Ammonia and Nickel Catalyst.
Close the autoclave. Take 5 kg pressure of Hydrogen Gas in the autoclave and start stirring
and heating. Heat the reaction contents to 55°C, hydrogenation starts. Maintain reaction
temperature in the range 55 to 65°C by circulating cooling water in the jacket. Carry out
reaction of Hydrogenation at 55 to 65°C maintaining Hydrogen pressure at 5 to 6 kg/cm2 for
three hours. When the absorption of hydrogen gas in the reaction mass is ceased, draw a
sample and analyzed on gas chromatogram to confirm complete conversion of Acetone.
Cool the reaction mass in the autoclave to 40 to 50°C by providing cooling in the jacket.
Settle the reaction mass for 1 hour. Release Hydrogen gas pressure from the autoclave.
Flush the autoclave with Nitrogen gas and filter the batch using sparkler filter to obtain crude
MIPA. This filtrate is taken for fractional distillation. Catalyst is deactivated with dilute
Hydrochloric acid and sent to the manufacturer for regeneration.
Stage II
The crude MIPA obtained from the above step is fractionated in a fractional distillation unit to
separate pure MIPA along with various impure fraction containing impurities. During the
course of fractional distillation, samples are drawn at regular intervals and distillation column
is continuously monitored by controlling vacuum & temperature to separate various
impurities as impure fractions. By maintaining proper reflux ratios and other conditions, pure
MIPA is collected as main fraction a special receiver assigned for it. It is then checked for
final quality testing and if found ok then packed and transferred to finished goods storage.
Route of Synthesis for Mono Iso Propyl Amine
+ +
Acetone Ammonia Hydrogen Gas Mono Propyl Amine
(MW-58.08) (MW-17) (MW-2) (MW-59.11)
H—H
Nickel Catalyst
Pre-Feasibility Report of
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FLOW CHART FOR MONO ISO PROPYL AMINE MANUFACTURING
i) Acetone
ii) Ammonia (Liquor)
iii) Nickel Catalyst
iv) Hydrogen Gas Autoclave
5 to 6 Kg/cm2 55
to 65 ºC
Pressure Filter
Mono Iso Propyl
Amine Crude
Transferred to
Distillation
High Vacuum
Fractional
Distillation System
Pure Mono Iso Propyl Amine
Residue sent to Hazardous Waste
Facility
(Output 2.4 to 2.6 MT/Annum)
Pre-Feasibility Report of
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E) Di Methyl Amine Hydrochloride (DMA.HCl)
Stage I
In a reactor fitted with column condenser & receiver, charge Dimethylamine (40%) dissolved
in Water. Start stirring and add required quantity of Hydrochloric (30%) to adjust pH of the
reaction mixture at 6 to 6.5. Stir the contents for 1 hour and apply slow heating and vacuum
to distill out specific quantity of water while maintaining reaction temperature at 45 to 50°C.
Cool the contents to 25°C and centrifuge the crystallized DMA.HCl. Collect the Mother
Liquor and use for next batch.
Stage II
The Crystalline DMA.HCl obtained above is the dried in Rotary Cone Vacuum Dryer (RCVD)
for 8 hours at 40°C. It is then unloaded and packed in Fiber board Drums.
Route of Synthesis for Di Methyl Amine Hydrochloride
+
Dimethylamine Hydrochloric Acid Dimethylamine Hydrochloride
(MW-45.10) (MW-36.50) (MW-81.60)
H—CL
Pre-Feasibility Report of
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FLOW CHART FOR DI METHYL AMINE HYDROCHLORIDE MANUFACTURING
i) Di Methyl Amine
ii) HCl
Reactor
Centrifuge
Dryer
Mother Liquor
Recycle
Pure Di Methyl
Amine HCl
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
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F) Furfurylamine
It is produced by Reductive Amination of Furfural with Ammonia and Hydrogen Gas in liquid
phase using Raney Nickel catalyst to form Furfurylamine with very high level of selective
leading to primary amines.
Technical Details:
Stage I:
In an 1100 Liters Autoclave, charge specific quantity of Furfural, ammonia and Raney Nickel
Catalyst. Close the autoclave and flush it with nitrogen to remove trapped air in the empty
space of the autoclave. Then flush the autoclave with Hydrogen to remove Nitrogen from the
empty place. Keep 0.5 Kg/cm2 hydrogen gas pressure in the autoclave and slowly heat the
reaction mass in the autoclave at 139 to 140ºC. The pressure in the autoclave will start rising.
Keep very slow purging of Hydrogen gas and maintain Hydrogen gas at 12 to 13.5 Kg/cm2 and
temperature at 65 to 95ºC.
Apply intermittent heating or cooling to maintain these conditions. After 22 hours of reaction
start drawing sample for GC analysis and check for conversion. At the end of 20 to 22 hours
Furfurylamine conversion will reach to 94.5 to 95% level with total impurities in the range 5 to
5.5% level with no trace of Unreacted Furfural. Stop the reaction at this stage by applying
cooling, release hydrogen, flush the Autoclave with nitrogen and filter the batch to get crude
Furfurylamine.
Stage II:
Crude Furfurylamine obtained in the Step 1 is taken in a distillation still and distilled under
vacuum (2mm of Hg) to recover Furfurylamine (99.5%).
The company has filed a patent for “Improved Process for Furfurylamine”. (Copy of patent is
enclosed)
Route of Synthesis for Furfurylamine
+ +
Furfuraldehyde Ammonia Hydrogen Gas Furfurylamine
(MW-96.09) (MW-17) (MW-2) (MW-97)
H—H
Nickel Catalyst
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
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FLOW CHART FOR FURFURYLAMINE MANUFACTURING
i) Furfural Crude
ii) Ammonia (Liquor)
iii) Nickel Catalyst
iv) Hydrogen Gas Autoclave
18 to 20 Kg/cm2
95 to 105 ºC
Pressure Filter
Furfurylamine
Crude Transferred
to Distillation
High Vacuum
Fractional
Distillation System
Pure Furfurylamine
Residue sent to Hazardous Waste
Facility
(Output 4.8 to 5.2 MT/Annum)
Pre-Feasibility Report of
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G) 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole
Crude)
Stage I: (Condensation & Hydrolysis)
Charge Dimethyl Formamide and 2, 3 Dichloro Phenol. Start stirring and heat at temperature
50 to 60˚C. Charge potassium carbonate, stop heating, start cooling and add nitro
compound at temperature 30 to 40˚C. Start heating, start distillation and complete. Charge
methanol, start stirring and add caustic solution, maintain temperature at 50 to 55 ˚C. Then
charge water at 40˚C. After addition is complete, stir for 30 min and then start centrifuge.
Stage II: (Hydrogenation)
Charge Methanol, PNA, & Catalyst, and flush with Nitrogen and Hydrogen. Start stirring and
hydrogen feeding. Give heat by applying steam in jacket and heat upto 45-46°C and stop
heating. Continue reaction at 55-60°C till hydrogen pressure inside is upto 5kg/cm2. Use
cooling water circulation in jacket, once there is no further rise in temperature and drop in
pressure is noticed at 5kg/cm2 for at least 30 minutes. When the end point of reaction is
indicated, stop hydrogen purging and stirring and allow settling for 1 Hr. Release hydrogen
pressure slowly up to 0.5 kg/cm2, flush with nitrogen pressure and filter through pressure
filter.
Stage III: (Cyclization)
Charge Methanolic solution in room temperature, add caustic lye under continuous stirring
and cool to 40°C. Start CS2 addition at 40°C and complete addition in 6 Hrs. After CS2
addition stir for ½ Hr. Start heating and reflux for 10 Hrs. Charge water, heat to 80°C and
maintain for one Hr. Cool to 60°C and start addition of acetic acid between 3-4 Hrs. After
addition of acetic acid stir for ½ Hr. Check the pH of reaction mass is 6 – 7. Centrifuge and
unload the material.
Stage IV: (Methylation)
Charge Methanol with above stage – III material at room temperature and stir for 1 Hr and
slowly add DMS at 35 - 40°C. Start heating slowly to 65°C to maintain reflux for 8 Hrs. After
completing the reaction, cool the reaction & filter through centrifuge.
Pre-Feasibility Report of
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Stage V: (Charcoal Treatment & Neutralization with Ammonia)
Charge Methanol and above stage – IV material and heat upto 60-65°C. Charge charcoal
and maintain for 1 Hr. Filter the reaction mass and collect the filtrate in SS reactor. Cool the
reaction mass at room temperature and add Liquor ammonia. Centrifuge the material and
dry to get the product in powder form.
Route of Synthesis for 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H
Benzimidazole (Triclabendazole Crude)
Stage I: (Condensation & Hydrolysis)
+
2,3 Dichlorophenol 3,4-Dichloro-6-Nitro Acetanilide
4-chloro-5(2,3-dichloro
phenoxy)-2-nitrophenyl
acetamide
(MW-163.00) (MW-249.05) (MW-375.59)
K2CO3
Pre-Feasibility Report of
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+ H2O
Stage II: (Hydrogenation)
4-chloro-5(2,3-dichloro
phenoxy)-2-nitrophenyl
acetamide
MeOH/Caustic Lye
5-chloro-4-(2,3-
dichlorophenoxy)-2-
nitroaniline
Water
(MW-375.59) (MW-18.00) (MW-333.55)
H2/R.N.Catalyst/MeOH
5-chloro-4-(2,3-
dichlorophenoxy)-2-
nitroaniline
4-chloro-5-(2,3-
dichlorophenoxy)-1,2-
Phenylenediamine
Hydrogen Gas
(MW-333.55) (MW-6.00) (MW-303.55)
3H2
Pre-Feasibility Report of
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Stage III: (Cyclization)
Stage IV: (Methylation)
Stage V: (Charcoal Treatment & Neutralization with Ammonia)
CS2/Caustic Lye/CH3COOH
4-chloro-5-(2,3-
dichlorophenoxy)-1,2-
Phenylenediamine
5-chloro-6-(2,3-dichlorophenoxy)-
1,3- dihydro Benzimidazole-2-
Thione
Carbon Di Sulfide
CH3OH
(MW-303.55) (MW-76.04) (MW-345.55)
DMS
5-chloro-6-(2,3-dichlorophenoxy)-
1,3- dihydro Benzimidazole-2-
Thione
5-chloro-6-(2,3-dichlorophenoxy)-2-
Methylthio-1H-Benzimidazole
Methosulphate
Di Methyl Sulphate
(MW-345.55) (MW-126) (MW-471.55)
MeOH/Charcoal
Ammonia
5-chloro-6-(2,3-dichlorophenoxy)-2-
Methylthio-1H-Benzimidazole
Methosulphate
6-chloro-5-(2,3-dichlorophenoxy)-2-
Methylsulfonyl-1H-Benzimidazole
(MW-471.55) (MW-359.65)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
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FLOW CHART FOR 6-CHLORO-5(2,3 DICHLOROPHENOXY)-2-METHYLTHIO 1H BENZIMIDAZOLE (TRICLABENDAZOLE CRUDE)
MANUFACTURING
Stage I: (Condensation & Hydrolysis)
Stage II: (Hydrogenation)
mm
SSR
(Condensation)
i) Dimethyl Formamide
ii) 2,3 Dichloro Phenol
iii) Potassium Carbonate
SSR
(Hydrolysis)
Centrifuge 4-Chloro-5-(2, 3- Dichloro
phenoxy)-2-nitroaniline
(Stage-I)
Dimethyl
Formamide
Recovery
vi) Methanol
vii) Stage-I
viii) Raney Nickel
Catalyst
ix) Nitrogen Gas
x) Hydrogen Gas
SSR
Filtration
4-Chloro-5-(2, 3-
Dichlorophenoxy)-1, 2-
Phenylenediamine (Stage-II)
SSR
(Hydrolysis)
Centrifuge 4-Chloro-5-(2, 3- Dichloro
phenoxy)-2-nitroaniline (Stage-
I)
i) Methanol
ii) Caustic Lye
iii) Water
ML
Transferred
to Recovery
i) Methanol
ii) Stage-I
iii) Raney Nickel Catalyst
iv) Nitrogen Gas
v) Hydrogen Gas
SSR
Filtration
4-Chloro-5-(2, 3-
Dichlorophenoxy)-1, 2-
Phenylenediamine (Stage-II)
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Stage III: (Cyclization)
Stage IV: (Methylation)
i) Stage-II with Methanol
ii) Caustic Lye
iii) Carbon Disulphate
iv) Acetic Acid
SSR
Centrifuge
5-Chloro-4-(2,3-
dichlorophenoxy)-1,3-
dihydrobenzimidazole-2-
thione (Stage-III)
ML
Transferred
to Recovery
i) Methanol
ii) Stage-III
iii) Dimethyl Sulphate
GLR
Centrifuge
5-Chloro-6-(2,3-Dichlorophenoxy)-
2-(Methylsulphate)-1H-
Benzimidazole (Stage-IV)
Methanol ML
Transferred to
Recovery
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Stage V: (Charcoal Treatment & Neutralization with Ammonia)
i) Methanol
ii) Stage-IV
iii) Charcoal
GLR
Filtration
SSR
Centrifuge
Drying
Milling
6-Chloro-5(2,3-Dichloro
phenoxy)-2-Methylsulfonyl-
1-H Benzimidazole
(Triclabendazole Crude N-
1) (Stage-V)
Liquor
Ammonia
Methanol ML
Transferred to
Recovery
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H) 5-Chloro-4-Amino-2,1,3- Benzothiadiazole
Stage I (Hydrogenation)
• Charge Ethyl Acetate • Charge PCONA (Para Chloro Nitro Aniline)
• Charge Raney Nickel Catalyst • Apply Hydrogen Gas & Hydrogen Pressure 4 Kg/cm2 • Continue Hydrogenation by Maintaining Temperature at 60 – 65°C • After Completion of reaction, filter reaction mass through Nutsche filter and wash the
bed with 50.0 L Ethyl Acetate • Take Ethyl Acetate filtrate in clean and dry vessel and distill Ethyl Acetate under
vacuum below 35-40°C • Drain the material in the drum
Stage II (Cyclization)
• Charge Dimethyl Formamide • Charge Stage I Material, stir the material for 30 Minutes at Room Temperature • Add Thionyl Chloride in 3-4 Hrs at 30 – 35°C • After Completion of reaction, quench the reaction mass in chilled water • Adjust the pH by the caustic solution pH upto 7 • Centrifuge the material
Stage III (Nitration)
• Charge Sulphuric Acid & cool to 10°C • Charge Stage II, stir the material for 30 Minutes at Room Temperature • After that slowly add Nitric acid, Temperature should be below 20°C • After completion of reaction mass, quench in chilled water • Centrifuge the material
Stage IV (Reduction)
• Charge Water / Toluene • Slowly add Iron powder
• Charge Stage III, heat slowly to 60°C and maintain for 2-3 hours • After completion of reaction, filter the reaction mass and collect the filtrate in SSR • Start toluene recovery under vacuum temperature 50-55°C • Filter the material in centrifuge and wash with methanol and suck dried to unload the
material • Dry the material at temperature 60-65°C, unload and pack the material as finished
product.
Pre-Feasibility Report of
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Route of Synthesis for 5-Chloro-4-Amino-2,1,3-Benzothiadiazole
Stage I (Hydrogenation)
Stage II (Cyclization)
Catalyst/H2/Ethyl Acetate
(MW-172.57) (MW-142.60)
Para Chloro Ortho Nitro
Aniline
4-Chlorobenzene-1,2-
Diamine
DMF/SOCl2
4-Chlorobenzene-1,2-
Diamine
5-Chloro-2,1,3-
Benzothiadiazole
(MW-142.60) (MW-170.62)
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Stage III (Nitration)
Stage IV (Reduction)
H2SO4/HNO3
5-Chloro-2,1,3-
Benzothiadiazole 5-Chloro-4-Nitro-2,1,3-
Benzothiadiazole
(MW-170.62) (MW-216.00)
Iron/Toluene
Methanol
5-Chloro-4-Nitro-2,1,3-
Benzothiadiazole
5-Chloro-4-Amino-
2,1,3-Benzothiadiazole
(MW-216.00) (MW-185.63)
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FLOW CHART FOR 5-CHLORO-4-AMINO-2,1,3- BENZOTHIADIAZOLE MANUFACTURING
Stage I (Hydrogenation)
Stage II (Cyclization)
i) Ethyl Acetate
ii) PCONA
iii) Raney Nickel
iv) Hydrogen Gas
v) Nitrogen Gas
SSR
Filter
Spent Catalyst
sent for
Reaction
SSR
4-Chlorobenzene-
1, 2-Diamine
(Stage-I)
Ethyl Acetate
Recovery
i) Di Methyl Formamide
ii) Stage-I
iii) Thionyl Chloride
GLR
GLR
Centrifuge
5-Chloro-2, 1, 3-
Benzothiadiazole (Stage-II)
Caustic Lye Quenching with
Water & Ice
ML Transferred to
ETP
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Stage III (Nitration)
Stage IV (Reduction)
i) Sulphuric Acid
ii) Stage-II
iii) Nitric Acid
SSR
Sintex
Centrifuge
Quenching with
Water & Ice
ML Transferred to
ETP
5-Chloro-4-Nitro-2, 1, 3-
Benzothiadiazole (Stage-III)
v) Water
vi) Toluene
vii) Iron
viii) Stage
SSR
Iron slug
transferred to
hazard waste
Centrifuge
Toluene
Recovery
Methanol
Washing
Filter
SSR
Drying
Milling
5-Chloro-4-Amino-2,
1, 3-Benzothiadiazole
(Stage-IV)
ML Transferred
to recovery
Sulphuric Acid
Stage-II
Sintex
Centrifuge
5-Chloro-4-Nitro-2, 1, 3-
Benzothiadiazole (Stage-III)
i) Water
ii) Toluene
iii) Iron
iv) Stage-III
SSR
Pre-Feasibility Report of
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I) 2-Furoic Acid
Stage I (Oxidation)
• Charge filter water and add Caustic Flakes under cooling.
• Start chilling upto 10 to 15°C.
• Start purging of chlorine at temperature below 15°C.
• Check pH & assay of hypochlorite solution.
• Addition of Furfural Aldehyde at temperature below 20°C.
• Digestion of reaction mass for 5 to 6 hours.
• Check pH & assay of hypochlorite solution. (Limit NMT 1%)
• Charge sodium chloride and stir for 60 minutes.
• Adjust the pH 7 (Neutral) by Hydrochloric Acid.
• Reaction mass to be transferred to GLR-03.
• Addition of Hydrochloric Acid upto pH Range 2 to 2.5.
• Check the pH & stir for 50 minutes.
• Centrifuge the material.
• Wash with 20% NaCl solution and unload the material.
Stage II (Purification)
• Charge filter water and charge 2-Furoic Acid crude material.
• Heat upto 50°C, then charge charcoal and start heating upto 95 to 100°C.
• Maintain temperature at 90 to 95°C for 1 hour.
• Start filtration & filtrate to be collected in GLR-02.
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• Stir & start cooling at room temperature.
• Start brine circulation, chill upto 15 to 20°C and maintain 1 hour.
• Centrifuge the material & wash with chilled water.
• Unload the material.
• Dry the material temperature at 65 to 70°C.
• Dry the material till LOD (Limit NMT 0.5%)
• Unload the material & Pack.
Route of Synthesis for 2-Furoic Acid
+ +
HCl
Furfural Sodium Hypochlorite 2-Furoic Acid
(MW-96) (MW-73.50) (MW-112)
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FLOW CHART FOR 2-FURIOC ACID MANUFACTURING
Stage I (Oxidation)
Stage II (Purification)
v) Water
vi) Caustic Flakes
vii) Chlorine
viii) Furfural
SSR
GLR
Centrifuge
Hydrochloric Acid Aqueous mother
liquor containing
Sodium Chloride
2-Furoic Acid Crude
iv) Water
v) Stage-I
vi) Charcoal
GLR
Filter
Centrifuge
Aqueous mother
liquor (Recycle)
2-Furoic Acid Pure
GLR
Drying Milling 2-Furoic Acid (Pure)
Packing
i) Water
ii) Caustic Flakes
iii) Chlorine
iv) Furfural
SSR
GLR
Centrifuge
Hydrochloric
Acid
2-Furoic Acid Crude
i) Water
ii) Stage-I
iii) Charcoal
GLR
Filter
ix) Water
x) Caustic Flakes
xi) Chlorine
xii) Furfural
SSR
GLR
Centrifuge
2-Furoic Acid Crude
GLR
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
J) Cyclohexenyl Ethyl Amine (CHEA)
Stage I
In a high pressure Autoclave, charge Cyclohexenyl Acetonitrile (CHAN), Catalyst and
Toluene. Close the autoclave. Take 10 kg pressure of Hydrogen Gas in the autoclave
and start stirring and heating. Heat the reaction contents to 70°C. Hydrogenation
starts. Maintain reaction temperature in the range 70 to 80°C by circulating cooling
water in the jacket. Carry out reaction of Hydrogenation at 70 to 80°C and maintain
10 to 15 kg/cm2 pressure for six hours. When the absorption of hydrogen gas in the
reaction mass is ceased, draw a sample and analyze on gas chromatogram to
confirm complete conversion of CHAN. Cool the reaction mass in the autoclave to 40
to 50°C by providing cooling in the jacket. Settle the reaction mass for 1 hour.
Release Hydrogen gas pressure from the autoclave. Flush the autoclave with
Nitrogen gas and filter the batch using sparkler filter to obtain crude Cyclohexenyl
Ethylamine (CHEA) and toluene mixture. This filtrate is taken for fractional distillation.
Catalyst is deactivated with dilute Hydrochloric acid and sent to the manufacturer for
regeneration.
Stage II
The crude Cyclohexenyl Ethylamine obtained from stage I is fractionated in a
fractional distillation unit to separate pure Cyclohexenyl Ethylamine along with
Toluene and various impure fraction containing impurities. During the course of
fractional distillation, samples are drawn at regular interval and fractional column is
continuously monitored by controlling vacuum & temperature to separate various
impurities as impure fractions. By maintaining proper reflux ratios and other
conditions pure Cyclohexenyl ethyl amine is collected as main fraction in a special
receiver assigned for it. It is then checked for final quality testing and if found ok,
pack and transfer to finished goods storage.
Route of Synthesis Cyclohexenyl Ethyl Amine (CHEA)
+
H—H
Nickel Catalyst
Toluene
Cyclohexene-1-
Acetonitrile
Hydrogen Gas Cyclohexenyl Ethylamine
(MW-121.18) (MW-2) (MW-125.21)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
FLOW CHART FOR CYCLOHEXENYL ETHYL AMINE (CHEA) MANUFACTURING
i) Cyclohexenyl Acetonitrile
ii) Toluene
iii) Nickel Catalyst
iv) Hydrogen Gas Autoclave
10 to 15 Kg/cm2
70 to 80ºC
Pressure Filter
Cyclohexenyl Ethyl
Amine Crude
Transferred to
Distillation
High Vacuum
Fractional
Distillation System
Toluene Recycled for
Process
Residue sent to Hazardous Waste
Facility
(Output 2.4 to 2.6 MT/Annum)
Pure Cyclohexenyl Ethyl
Amine
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
3.6 RAW MATERIAL REQUIRED ALONG WITH ESTIMATED QUANTITY, LIKELY
SOURCE, MARKETING AREA OF FINAL PRODUCTS, MODE OF TRANSPORT OF RAW
MATERIALS AND FINISHED PRODUCTS:
3.6.1 Raw Material Required Along with Estimated Quantity
List of Raw Material and their annual consumption Sr. No.
Name of Raw Material Raw Material Consumption Per Annum
Unit
Hydrogen Gas (Capacity: 18.72 Lacs NM3 TPA)
1 Methanol 1180.00 TPA
2 D.M Water 675.00 TPA
Furfuraldehyde (Capacity: 600 TPA)
1 Corn Cobs 7038.00 TPA 2 Sulphuric Trioxide 210.00 TPA
Furfuryl Alcohol (Capacity: 360 TPA)
1 Furfuraldehyde 396.00 TPA
2 Raney Nickel Catalyst 18.00 TPA
3 Hydrogen Gas (NM3) 129.60 TPA 4 Nitrogen Gas (NM3 14.40 TPA
Mono Isopropyl Amine (Capacity: 120 TPA)
1 Acetone 146.00 TPA
2 Ammonia (Liquor) 34.50 TPA
3 Raney Nickel Catalyst 6.00 TPA
4 Hydrogen Gas (NM3) 43.20 TPA
5 Nitrogen Gas (NM3) 4.80 TPA Di Methyl Amine Hydrochloride (Capacity: 1200 TPA)
1 Di Methyl Amine (40%) 2088.00 TPA
2 HCl (30%) 1030.00 TPA
Furfurylamine (Capacity: 240 TPA)
1 Furfuraldehyde 280.00 TPA
2 Ammonia Gas 52.80 TPA
3 Raney Nickel Catalyst 12.00 TPA
4 Hydrogen Gas (NM3) 86.40 TPA 5 Nitrogen Gas (NM3) 9.60 TPA
6-Chloro-5(2,3- Dichlorophenoxy)-2-Methylthio 1H Benzimidazole Triclabendazole (Crude) (N-1) (Capacity: 100 TPA)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
1 2,3 Dichloro Phenol 72.50 TPA
2 4,5 Dichloro-2-Nitroacetanilide 109.00 TPA
3 Dimethyl formamide 110.00 TPA 4 Potassium Carbonate 66.70 TPA
5 Methanol 1800.00 TPA
6 Caustic Lye 115.00 TPA
7 Hydrogen Gas (NM3) 32.00 TPA
8 Raney Nickel Catalyst 1.80 TPA
9 Carbon disulphide 47.00 TPA
10 Acetic Acid 40.00 TPA
11 Di methyl Sulphate 67.00 TPA
5-Chloro-4-Amino-2,1,3-Benzothiadiazole (TNZ) (Capacity: 24 TPA)
1 Para Chloro ortho nitro aniline 36.00 TPA
2 Ethyl acetate 30.00 TPA
3 Raney Nickel Catalyst 0.432 TPA
4 Hydrogen Gas (NM3) 12.48 TPA
5 Dimethylformamide 84.00 TPA
6 Thionyl chloride 39.00 TPA
7 Caustic Lye 36.00 TPA
8 Sulphuric Acid 180.00 TPA
9 Nitric Acid 12.33 TPA
10 Iron Powder 26.40 TPA
11 Toluene 56.00 TPA
12 Methanol 28.80 TPA
2-Furoic Acid (Capacity: 60 TPA)
1 Furfural Aldehyde 90.00 TPA
2 Caustic Flakes 128.40 TPA
3 Chlorine 75.60 TPA
4 Sodium Chloride 57.60 TPA
5
Charcoal
750.00
TPA
Cyclohexenyl Ethyl Amine (Capacity: 120 TPA)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
1 Cyclohexenyl Acetonitrile 162.00 TPA
2 Toluene 24.12 TPA
3 Raney Nickel Catalyst 6.00 TPA
4 Hydrogen Gas (NM3) 69.12
TPA
5 Nitrogen Gas (NM3) 4.90
TPA
3.6.2 Raw Material Source
Sr.No Product Source of Raw Materials for Products
Key Raw Materials Raw Material Source
1 Hydrogen Gas Methanol • It is indigenously and abundantly
available in India.
• Non-Petroleum based and therefore
their availability is without much
variation in input prices.
2 Furfuraldehyde Corncobs/Bagasse • Corncobs are available in Aurangabad
distreict predominantly in Kannad,
Sillod, Soyagaon, Vaijapur, Phulambri
and Jalgaon district.
• Bagasse is abundantly available in
Ahmednagar district as many sugar
factories are located nearby.
3 Furfuryl Alcohol
Furfuraldehyde
• Galaxy is going to manufacture
Furfuraldehyde, it can be consumed
captively whenever required.
4 Furfurylamine Furfuraldehyde • Galaxy is going to manufacture
Furfuraldehyde, it can be consumed
captively whenever required.
5 2-Furioc Acid Furfuraldehyde Same as above
6 Mono Iso Propyl Amine Acetone • It is indigenously and abundantly
available in India.
7 Di Methyl Amine
Hydrochloride
Di Methyl Amine
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
• Non-Petroleum based and therefore
their availability is without much
variation in input prices.
8 Cyclohexenyl Ethyl
Amine (CHEA)
Cyano Acetic Acid • Cyano Acetic Acid is available only in
China and can be imported in huge
quantity when required.
9 6-Chloro-5(2,3
Dichlorophenoxy)-2-
Methylthio 1H
Benzimidazole
(Triclabendazole
Crude)
4,5-Dichloro 2-Nitro
Acetanilide (TC-III)
• Triclabendazole Crude is a product
which involves multiple stages and the
previous output becomes the raw
material input for the next stage of
operation.
• Galaxy will procures material from
outside for the first three stages and
processes it ahead.
10 5-Chloro-4-Amino-
2,1,3- Benzothiadiazole
(TNZ)
Para Chloro Ortho
Nitro Aniline
• It is indigenously and abundantly
available in India.
3.6.3 Marketing Area of Final Products
Galaxy proposes to continue its existing strategy of direct marketing both for the
domestic market as well as for its new products for exports.
Furfural, Furfuryl Alcohol and Furfurylamine are in great demand in India and the
consumption of these chemicals is increasing rapidly.
Company’s API Intermediates namely, 2-Furioc Acid, 5-Chloro-4-Amino-2,1,3-
Benzothiadiazole (TNZ), 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H
Benzimidazole (Triclabendazole Crude), Cyclohexenyl Ethyl Amine (CHEA), Di Methyl
Amine Hydrochloride are currently being sold to multi-national companies (MNC’s) like
Dr. Reddy’s Laboratories, Sequent Scientific, Wochardt Ltd, Survival Technologies, NGL
Pharma, etc. The company has identified higher demand for these products from existing
and new customers.
Galaxy has already developed its own marketing network for local as well as for exports. As a policy, company has restricted intermediaries’ since inception. Since Galaxy’s brand is well established for Furfurylamine, Furfuryl Alcohol and other existing products the company would not face constraints in marketing the proposed products. Galaxy stands fully committed to its quality since beginning and this has given the company brand name in local and export market. Company is well known for its products.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
The processes developed for MIPA, DMA.HCl ensures high profitability due to high
yields and in-house availability of Hydrogen Gas with no dependability on petroleum
products & their ever increasing prices. Therefore, Galaxy can market these products at
a competitive price compared to the others.
The demand for Hydrogen gas is increasing for its property of making the chemical
processes pollution free. The captive consumption of hydrogen gas will benefit the other
products of the company by making them cost effective.
Galaxy will have tie-ups with agents to transport the surplus hydrogen gas to customers
with requirement of the same.
3.6.4 Mode of Transportation of Raw Materials and Finished Products
The aforesaid raw materials are transported by road/sea/air to the manufacturer’s site at
Newasa (Pune-Aurangabad Highway).
3.7 RESOURCE OPTIMIZATION/RECYCLING AND REUSE ENVISAGED IN THE
PROJECT
Corn cob which is a waste will be used as a raw material for manufacturing of
furfuraldehyde. Biomass generated in this product is of good fuel value and can be directly
used as boiler fuel. After treatment of waste water these water will be used for gardening.
3.7 AVAILABILTY OF WATER ITS SOURCE, ENERGY/POWER REQUIREMENT AND
SOURCE SHOULD BE GIVEN
Sr.No PARTICULARS REQUIREMENT SOURCE
1 Water 84 M3/Day Water will be supplied by
Newasa MIDC.
2 Power 320 KVA
(Capacity of
Transformer)
The power is given by the
MSEB (Maharashtra State
Electricity Board). Subsidies
are provided by MSEB on
completion of the project.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
3.8 QUANTITY OF WASTE TO BE GENERATED (LIQUID AND SOLID) AND SCHEME
FOR THEIR MANAGEMENT/DISPOSAL
Sr.
No
Product Waste Quantity Management /
treatment
1 Hydrogen Gas Vent Gases
Carbon di oxide
CO2 - 55-88% +
Carbon Oxide
CO - 0-2% +
Hydrogen
H2 - 40% v/v
14.22 Lacs
NM3/Annum at
190 NM3/Hr
The vent gases will
be collected in the
seal pot, of which
Hydrogen is
discharged through
11 Mtr height
chimney with flame
arrester and CO2 will
be collected from the
seal pot and sold.
2 Furfuraldehyde Distillation Residue 12 to 12.4
MT/ANNUM
The waste will be
collected and treated
in Common
hazardous waste
management &
treatment facility at
Ranjangaon.
3 Furfuryl Alcohol Distillation Residue Output 7.2 to 7.6
MT/Annum
4 Furfurylamine Distillation Residue 4.8 to 5.2
MT/Annum
5 Mono Iso Propyl
Amine
Distillation Residue 2.4 to 2.6
MT/Annum
6 Cyclohexenyl Ethyl
Amine (CHEA)
Distillation Residue 2.4 to 2.6
MT/Annum
7 Di Methyl Amine
Hydrochloride
Nil Zero Discharge -
8 2-Furioc Acid Acidic Water 360 M3/Annum Acidic Water treated
at Effluent Treatment
Plant (ETP) and
used for green belt
development and for
dust suppression /
sprinkling purpose.
9 6-Chloro-5(2,3
Dichlorophenoxy)-2-
Slight Alkaline Water 600 M3/Annum Slight Alkaline Water
treated at Effluent
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Methylthio 1H
Benzimidazole
(Triclabendazole
Crude)
(7.5 to 8 pH) Treatment Plant
(ETP) and used for
green belt
development and for
dust suppression /
sprinkling purpose.
10 5-Chloro-4-Amino-
2,1,3-
Benzothiadiazole
(TNZ)
Neutral Water
(6.5 to 7 pH)
504 M3/Annum Neutral Water
treated at Effluent
Treatment Plant
(ETP)and used for
green belt
development and for
dust suppression /
sprinkling purpose.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
3.10 SCHEMATIC REPRESENTATIONS OF THE FEASIBILITY DRAWING WHICH GIVE
INFORMATION OF EIA PURPOSE
The applicability of the EIA Notification 2006, for the proposed project was explored by considering different possibilities & provision made in the said notification considering the products & project location.
Screening Category B
(As project is in notified industrial area)
Project falls under B1 category as per EIA notification 2006 it falls
in category 5(f) of schedule I, EIA study is required
Form I, PFR+ Proposed TOR
Scoping by SEAC
TOR approved by SEAC
EIA study & Preparation of Report
Submission of EIA report to Dept. of Environment Maharashtra
Appraisal by SEAC
Recommended Not Recommended
Approval from SEIAA
Grant of EC Rejected
Project concept
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 4
SITE ANALYSIS
4.1 CONNECTIVITY
Connectivity The Site is located on Aurangabad-Pune Highway.
Distance from Pune : 177 Km
Distance from Aurangabad: 73 Km
Distance from Ahmednagar : 22 Km
Distance from Mumbai : 290 Km
Distance from Nearest Village (Godegaon): 1 Km
Distance from Nearest Hospital
(Shaneshwar Gramin Rugnalay – Shanishingnapur) : 10 Km
Distance from Nearest Fire Station (Ahmednagar MIDC): 22 Km
Distance from Nearest Police Station (Sonai): 1 Km
Distance from Nearest Airport (Aurangabad): 75 Km
Distance from Nearest Bus Stand (Godegaon): 1 Km
Distance from Nearest Railway Station (Ahmednagar): 24 Km
Distance from Nearest Sea Port (Mumabai) : 340 Km
4.2 LAND FORM, LAND USE AND LAND OWNERSHIP
Sr. No Particulars Description
1 Land Form MIDC Industrial Land (Newasa)
2 Land Use Barren land
3 Land Ownership Maharashtra Industrial Development Corporation -
Nashik (Leased to Galaxy Laboratories Pvt Ltd for
99 years)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
4.2 TOPOGRAPHY
Topography of land is more or less plain terrain without much undulation.
Google Map
4.4 EXISTING LAND USE PATTERN
Total Land Area = 48400 Sq.Mtr
Built Up area = 10275.26 Sq.Mtr
Below mentioned table gives brief information regarding environmental setting of the project
site:
Sr.No Particulars Distance from the Site
1 Forest 5.85 km
2 Water Bodies
Stream
Panas odha
Bhar bhordi odha
4.8 km
4.6 km
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
(Dam)
40 Km
3 National Park Nil
4 Wildlife Sanctuary Nil
5 Eco Sensitive Areas
Ahmednagar reserved forest
Bahirwadi Reserved Forest
6.5 km
9.3 km
6 River- Ghodegaon river 4.6 Km
7 Coastal Regulation Zone (CRZ) Nil
4.5 EXISTING INFRASTRUCTURE
The proposed site is well connected by road. State highway SH-60 is 200 m away from the
site. As the site is in notified industrial area all infrastructure are well developed and in
place
4.6 SOIL CLASSIFICATION
The soil in the area is black cotton soil (Plain Terrain).
4.7 CLIMATIC DATA FROM SECONDARY SOURCES
The climatic condition of this area is semi-arid. The maximum temperatures goes upto 45°C
during summer in the month of May and the minimum temperature goes down to 10°C
during winter in the month January – February. The wind in this area is light to moderate
during summer and winter. The rainfall of this district is 750mm. Generally light and
moderate, particularly during the morning hours. While during the afternoon hours the winds
were stronger.
4.8 SOCIAL INFRASTRUCTURE
Social Infrastructure will be developed as per need based in the villages of the vicinity of the
project.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 5
PLANNING BRIEF
5.1 PLANNING CONCEPT
The proposed project is based on eco friendly technology of Hydrogenation and value added
derivates, which will be manufactured from Furfuraldehyde. The following are points of focus
in the Proposed Project:
Manufacturing of Hydrogen Gas from the first of its kind - Indian Made Hydrogen Plant.
Corns and sugarcane are extensively cultivated in near by areas, this will greatly facilitate
the procurement of corn cobs and baggasse and manufacturing Furfural from agricultural
waste (Corn Cob).Thus promoting corn and sugarcane cultivation near by villages.
Manufacturing value added derivatives of Furfural i.e. Furfuryl Alcohol, Furfurylamine & 2-
Furoic acid
For increasing production capacity of Triclabendazole (N-1), 5-Chloro-4-Amino-2,1,3-
Benzothiadiazole (TNZ) & CHEA which is being manufactured at our Aurangabad unit
presently. We are proposing these chemicals in API Unit (Newasa) also, for meeting present
customer increase in demands.
Vision of this project is to manufacture pollution free API intermediates, which are in huge
demand in API, Agro and other allied industries.
The project is situated in the “D-Zone” of the development sector and the unit is entitled to
subsidiaries like power, interest cost, and sales tax.
Project site is not situated within the city limits, no thick residential area is in proximity and
thus will not be affected by the ancillary effects of the manufacturing unit. (For e.g. Noise,
odor etc)
The proposed project is about 50 km from the existing plant of Galaxy at Aurangabad and is
located adjacent to Aurangabad- Pune Highway. The location is strong in infrastructure and
greatly facilitates for transportation of raw material and finished products.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
5.2 POPULATION PROJECTION
There are no major human settlements in the vicinity of the project site. The manpower
requirement will be sourced from the local areas to the extent possible; hence not much of
settlement of outside people in the area. However, population concentration may increase
around the project site due to increase in ancillary activities
5.3 LAND USE PLANNING
Given below is the land use planning with break-up details of the defined areas:
SR.NO ITEM AREA IN SQ.MTRS
1 Built-Up Area
(Manufacturing Area, Administrative Building,
Security Cabins, R & D Laboratory, Wash room
facilities, Water Tanks, etc.)
2350
2 Storage
(Methanol Storage, Raw Material Storage,
Finished Goods Storage etc.)
2448
3 Green Belt 4715
4 Effluent Treatment Plant (ETP) 1377
5 Corn Cultivation Area (For R & D) 5040
6 Internal Roads 5136
7 Open Space 27334
Total Area 48400
5.4 ASSESSMENT OF INFRASTRUCTURE DEMAND (PHYSICAL & SOCIAL)
The project site is located in notified industrial area wherein all required physical
infrastructure are available as well as underdevelopment (i.e Road, water supply, Electricity,
etc)
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
The project site is situated near Aurangabad and Ahmednagar district which gives easy
access to workers for facilities such as hospitals, Markets and education for workers
children.
Corporate social responsibility will be taken up in the form of setting-up school, hospital,
recreational activities (playground) for villages.
5.5 AMENITIES/FACILITIES
Facilities like drinking water, canteen, and sanitation facility will be provided in the proposed
plant as basic requirements for workers. Transportation facilities will be provided for
employees not in proximity from the unit.
On commencement of the manufacturing site, further amenities will be identified and
incorporated.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 6
PROPOSED INFRASTRUCTURE
6.1 INDUSTRIAL AREA (PROCESSING AREA)
The processing area consists of the following:
A) Manufacturing Unit:
This unit will comprise of all the equipments and machineries required for
manufacturing of API intermediates. The manufacturing unit will be split into
Hydrogenation Plant along with distillation columns and Multi-purpose plant.
B) Hydrogen Plant:
The Hydrogen Plant is a stand-alone unit erected at a considerable distance from the
manufacturing unit and will comprise of a control room which will operate and monitor
the functioning of the Hydrogen plant for the production of Hydrogen gas. The set-up
for the Hydrogen Plant is independent to that of the manufacturing unit.
C) Utilities:
All the utilities required to start operation of the manufacturing and hydrogen plant
comprising of transformer, boiler, thermo-packs, DG set etc are set-up in proximity.
D) Warehouse:
The unit proposes to have the following warehouses:
• Raw Material
• Intermediate
• Finished
• Cold Storage
• Hazardous Material
A) Quality Control Laboratory:
The quality control laboratory will be set-up for the purpose of testing and analysis.
B) Effluent Treatment Plant (ETP):
The ETP is set-up for processing industrial waste/effluent and using the treated water
for gardening.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
6.2 RESIDENTIAL AREA (NON-PROCESSING AREA)
The non-processing area consists of the following:
A) Administrative Block:
The administrative block comprises of:
• Main Office
• Conference Room
• Reception
• Pantry
• Rest Rooms
• Guest House
A) Security Cabins:
There are two security cabins one at the entrance and the other at the second
service road entrance.
B) Sanitation Area:
Restrooms and bathrooms are placed at relevant distances within the site.
C) Canteen:
The company will allocate a canteen for employees to have their meals. The canteen
will accommodate 100 employees at once.
D) Parking Area:
The company will allocate sufficient parking area for 2-wheeler, 4-wheeler and for
heavy vehicles.
6.3 GREEN BELT
About one-third of total land availability is reserved for plantation. The company has already
done plantation in the perimeter of the land area. The company has also dedicated an area
for corn research, wherein corn cultivation is done. Lawns will be spread for aesthetically
balancing the land area.
SR.NO ITEM AREA IN SQ.MTRS
1 Green Belt 4715
2 Corn Cultivation Area 5040
3 Lawns 520
Total Area 10275
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
6.4 SOCIAL INFRASTRUCTURE
Depending on the growth of the company the required social infrastructure will be provided.
6.5 CONNECTIVITY
The present site is located on Aurangabad-Pune Highway and is well connected. The traffic
on this highway is not dense and is a free-flow route.
SR.N
O
COMPONENT DESCRIPTION
1 Road Maharashtra SH-60:- 200 m
2 Railway Ahmednagar: 24 Km
3 Airport Aurangabad: 75 Km
4 Sea Port Nhava Sheva Mumbai: 340 Km
6.6 DRINKING WATER MANAGEMENT (SOURCE & SUPPLY OF WATER)
Drinking water will be purified with RO (Reverse Osmosis) system. The source of the water
will be from MIDC which will be purified for drinking purpose.
6.7 SEWERAGE SYSTEM
Sewage pipes would be laid in the entire company for the removal and disposal of mainly
non-harmful liquid wastes from the offices, canteen, and domestic waste coming from
different sections. This domestic effluent collected through sanitation areas will be collected
through well-designed sewer network and disposed to septic tanks and soak pit.
6.8 INDUSTRIAL WASTE MANAGEMENT
The following is the brief description of the Effluent Treatment Plant (ETP) for treating industrial waste.
Stage 1:
All waste discharged from the plant which is in the form of liquid, solid, and sludge is collected in the Effluent Collection Tank. The waste collected is both acidic and alkaline.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Stage 2:
The waste is then filtered from Effluent Collection Tank (where the maximum amount of sludge settles and is sent to the Sludge Drying Bed 1), and the effluent flows through oil & grease traps where oil and grease is collected in the trap and the effluent is collected in a Pre-Neutralization Tank.
Stage 3:
The effluent in Pre-Neutralization Tank is sent to Neutralization Tank. If the effluent is acidic (Above pH 7), Caustic Lye is used for neutralization. If the waste water is alkaline (Below pH 7), HCl is used for neutralization.
Stage 4:
After the effluent is neutralized, it is sent to the Primary Settling Tank through a pre-filter. From pre-filter effluent is collected in Primary tank, where it allows the settling of solids and the solids are drained out to the Sludge Drying Bed 1 and the effluent flows to the Aeration Tank.
Stage 5:
The bacteria in the Aeration Tank are developed to remove the COD (Chemical Oxygen Demand) & BOD (Biochemical Oxygen Demand) from the effluent by developing a suitable culture which is called as Mixed Liquor Suspended Solids (MLSS). The culture is formed to reduce the organic and inorganic load by treating it with urea, cow dung or jaggery.
Stage 6:
After aeration, the effluent is collected in Secondary Settling Tank to remove excess bacteria/sludge. The sludge is then drained to the Sludge Drying Bed 2, whereas the treated effluent is collected in a Pre-Filter Tank.
The remaining water in the Sludge Drying Bed 1 is drained and is moved back to Effluent Collection Tank for reprocess. The remaining water in the Sludge Drying Bed 2 is drained and moved to Pre-Neutralization Tank for reprocess.
Stage 7:
The treated effluent in the Pre-Filter Tank is passed to the multimedia filter. The multimedia filter contains sand and carbon used to filter the treated effluent for removing the odor and suspended solids. The water after filtration is then used for gardening.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
The sludge collected in the Drying Beds will be disposed to CHWTH facility authorized by (MPCB-Maharashtra Pollution Control Board).
Effluent Treatment Laboratory Details:
Company has provided a full fledge laboratory to undertake all chemical analysis related to ETP work.
The laboratory is provided with all necessary equipment to run the ETP properly to achieve required specification of the treated water.
6.9 SOLID WASTE MANAGEMENT
The solid waste will be collected by CHWTH facility authorized by (MPCB-Maharashtra
Pollution Control Board).
6.10 POWER REQUIREMENT & SUPPLY/SOURCE
The capacity of the transformer is 320 KVA. The power is given by the MSEB (Maharashtra
State Electricity Board). Subsidies are provided by MSEB on completion of the project
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
Flow Diagram of Effluent Treatment Plant
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 7
REHABILITATION AND RESETTLEMENT
(R & R) PLAN
This chapter is not applicable for the proposed project as there is no rehabilitation and
resettlement required in the project site as there are no habitations. No personnel are
affected due to this project.
This property is under the authority of Maharashtra Industrial Development Corporation
(Regional Office - Nashik) and is exclusively allocated for Industries.
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 8
RPROJECT SHEDULE AND COST ESTIMATION
Sr. No.
Heads of expenditure Expenditure Incurred till the
date of application
Expenditure to be Incurred
Total
1 Land 201 - 201
2 Site Development 46 46
3 Building/Civil Works -
1) Factory - 250 0
2) Administration -
TOTAL - 250
4 Plant & Machinery -
1) Imported - 0
2) Indigenous 40.56 681.44 722
5 Laboratory Equipments - 25 25
6 Deposits, Statutory fees etc 6 20 26
7 Miscellaneous Fixed Assets 10 10
8 Pre-Operative Expenses -
a) Manpower cost during Construction Period
- -
b) Interest during
c) Construction Period
- -
9 Effluent Treat Plant 50 50
10 Contingency - 25 25
11 Margin money for working capital
- 75 75
TOTAL 293.56 1136.44 1430
Pre-Feasibility Report of
M/S Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and
speciallity Agro chemicals (Newasa)
CHAPTER – 9
ANALYSIS OF PROPOSAL
(FINIAL RECOMMENDATIONS)
Due to implementation of proposed chemical unit the people of nearby areas / villages will be
benefited by way of generation of direct as well as indirect employment opportunities.
Skilled and Unskilled workers will be procured from nearby villages and for other other
employment /staff preference will be given to local villagers based on the skill, merit cum need
basis.
During construction stage approx. 150 persons will be hired. The project creates employment to
approx. 350 persons once the plant comes to the operational stage.
With the development of this plant there will be a lot of scope for more ancillary development,
which in turn will benefit the local people.
This will uplift financial and social condition of local people leading to overall improvement in
the income level of the people.
Manufacturing of furfural requires corncobs or bagasse in high tonnage which can be achieved
by providing the local farmers with seeds which will directly benefit the farmers in terms of fixed
income and cultivation of corn round the year.
Agriculture – Cooperative Society will be formed, wherein the farmers will be benefited and
there will be growth in agriculture.
Corporate social responsibility will be taken up in the form of setting-up school, hospital,
recreational activities (playground) for villages by Galaxy.
Hence, there will be an overall upliftment of socio-economic status of the people in the area
with the implementation of the project.
Manufacturing of furfural, furfurylamine, furfuryl alcohal in India will avoid imports from
international markets. The country will be self reliant thus reducing dependability of Indian API,
allied manufacturers on International market and forex (foreign exchange) risk. And the
products have potential being exported as these products are in high demand which has
positive financial effects at national and to the regional level.
Need based survey will be carried out in near by villages during baseline data generation and
details CSR will be outlined accordingly.