preface

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Shaw & Ramwell: Preface PREFACE 5 It was a great pleasure for us t o welcome old and new friends to this conference. Three years ago we held a Symposium on Prostaglandins+ a t the Worcester Foundation, and it was a sad timetfor Dr. Gregory Pincus had just died. He spoke often about potential luteolytic and luteotropic factorstand his vision has since been justified,for one of the major developments in the field of reproductive physiol- ogy since 1967 has been the demonstration of the remarkable effects of prostaglandins on steroidogenesis,luteolysis, abortion and in termination of pregnancy. At this recent meeting,owing to the intensity of in- terest and relevance of prostaglandins to population con- trollthere were three sessions on reproduction,one of which was added during the conference. Unfortunately,some highly significant areas of research could not be included in the programland to those working in these areas we extend our sincere apologies. We wish to thank the more than 500 registrants from 28 countries for their attendance,and we are grateful to the Academy staff and our chairmen for all their help and enthusiasm. It is a particular pleasure to thank our organ- ization secretary,Dorothy Schnurr,for helping us from the first letters about the Conference to the typing and proof- ing of the last pages of the Proceedings. The photo offset process has been used,since the prime purpose of this Conference was to elicit information and ideas for rapid dissemination by the Academy throughout the world,to all those with immediate interests in the prostaglandins, and also to those who have yet to turn their attention to this remarkable field. We also wish to express our appreciation and indebted- ness to the following organizations for their financial s uppor t : Agency for International Development,Washington,D.C. Allergan PharmaceuticalstCalifornia Alza Corporation, California Ciba Pharmaceutical Co. ,New Jersey G.D. Searle & Co.,Illinois Hoffmann-La Roche I n c . ,New Jersey Merck,Sharp & Dohme,New J e r s e y Office of Naval Research,Washington,D.C. Syntex Laboratories Inc. ,California Upjohn Company,Michigan Wallace Pharmaceuticals, New Jersey Jane Shaw and Peter Ramwell Conference Chairmen ?Prostaglandin Symposium of the Worcester Foundation for Experimental Biology,Interscience,N.Y. 1968.

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Shaw & Ramwell: Preface

PREFACE

5

I t w a s a g r e a t p l easu re f o r us t o welcome o l d and new f r i e n d s t o t h i s conference. Three yea r s ago w e he ld a Symposium on Pros tag landins+ a t t h e Worcester Foundation, and it w a s a s ad t i m e t f o r D r . Gregory Pincus had j u s t d i ed . H e spoke o f t e n about p o t e n t i a l l u t e o l y t i c and l u t e o t r o p i c f a c t o r s t a n d h i s v i s i o n has s i n c e been j u s t i f i e d , f o r one of t h e major developments i n t h e f i e l d of reproduct ive phys io l - ogy s i n c e 1 9 6 7 has been t h e demonstrat ion of t h e remarkable e f f e c t s of p ros t ag land ins on steroidogenesis,luteolysis, abor t ion and i n te rmina t ion of pregnancy.

A t t h i s r e c e n t meeting,owing t o t h e i n t e n s i t y of in - terest and re levance of p ros t ag land ins t o popula t ion con- t r o l l t h e r e w e r e t h r e e s e s s i o n s on reproduct ion ,one of which w a s added dur ing t h e conference. Unfortunately,some h igh ly s i g n i f i c a n t areas of r e sea rch could n o t be inc luded i n t h e programland t o those working i n these a r e a s w e extend our s i n c e r e apo log ie s .

W e wish to thank t h e more than 500 r e g i s t r a n t s from 28 c o u n t r i e s f o r t h e i r a t tendance ,and w e are g r a t e f u l t o t h e Academy s t a f f and our chairmen f o r a l l t h e i r h e l p and enthusiasm. I t i s a p a r t i c u l a r p l easu re t o thank our organ- i z a t i o n secre ta ry ,Dorothy Schnur r , fo r he lp ing us from t h e f i r s t let ters about t he Conference t o t h e typing and proof- i n g of t h e l a s t pages of t he Proceedings.

The photo o f f s e t p rocess has been used , s ince t h e prime purpose of t h i s Conference was t o e l i c i t in format ion and ideas f o r r a p i d d isseminat ion by t h e Academy throughout t h e w o r l d , t o a l l t hose wi th immediate i n t e r e s t s i n t h e p ros t ag land ins , and a l s o t o those who have y e t t o t u r n t h e i r a t t e n t i o n t o t h i s remarkable f i e l d .

W e a l s o wish t o express our a p p r e c i a t i o n and indebted- ness t o t h e fol lowing o rgan iza t ions f o r t h e i r f i n a n c i a l s uppor t :

Agency f o r I n t e r n a t i o n a l Development,Washington,D.C. Allergan Pha rmaceu t i ca l s tCa l i fo rn ia Alza Corporat ion, C a l i f o r n i a Ciba Pharmaceut ical Co. , N e w J e r sey G.D. S e a r l e & C o . , I l l i n o i s Hoffmann-La Roche Inc . , N e w J e r sey Merck,Sharp & Dohme,New Je r sey O f f i c e of Naval Research,Washington,D.C. Syntex Labora to r i e s Inc . , C a l i f o r n i a Upjohn Company,Michigan Wallace Pharmaceut icals , N e w J e r sey

Jane Shaw and Peter Ramwell Conference Chairmen

?Pros tag landin Symposium of t h e Worcester Foundation f o r Experimental Bio logy , In te rsc ience ,N.Y. 1 9 6 8 .