prenatal care new
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Almost a century after itsintroduction, prenatal care has become one
of the most frequently used health services inthe United States A planned program of medical evaluation and
management, observation, and education of
the pregnant woman directed toward makingpregnancy, labor, delivery and thepostpartum recovery a safe and satisfyingexperience.
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Well-designed prenatal program should providethe oppurtunities:
For the physician and the patient to become betteracquainted
For the physician to learn something about thepatients emotional attitude toward pregnancy andlabor
For instruction of the patient and her husband inoptimal care for herself and the coming baby
Optimal instruction of the patient and herhusband in a prepared childbirth program
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24%
20%
16%
9%
8%
5%
5%
5%3%
2% 2% 1% Gestational Hypertension
Diabetes
Anemia
Hydramnios/oligohydramnios
Lung Disease
Genital Herpes
Chronic Hypertension
D(Rh) Sensitization
Cardiac disease
Renal Disease
Incompetent cervix
Hemoglobinopathy
Data from Martin and Assocaiates (2002b)
Data from Martin and Associates (2002b)
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Varied by social and ethnicgroup, age and method of payment
Late identification of pregnancy by the
patient most common
Lack of money or insurance for suchcare
Inability to obtain an appointment
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The current low maternal mortality rate of
approximately 8 per 100,000 is likely
associated with the high utilization of prenatal care
Prenatal care was associated withsignificantly lower rates of preterm births as
well as neonatal death associated withseveral high-risk conditions that included
placenta previa, fetal-growth restriction, and
postterm pregnancy
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A comprehensive antepartum care program
involves a coordinated approach to medical
care and psychosocial support that optimallybegins before conception and extends
throughout the antepartum period
This comprehensive program includes:
(1) preconceptional care
(2) prompt diagnosis of pregnancy
(3) initial prenatal evaluation
(4) follow-up prenatal visits
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The diagnosis of pregnancy usually begins
when a woman presents with symptoms, and
possibly a positive home urine pregnancy testresult
Sonography is often used, particularly inthose cases in which there is question about
pregnancy viability or location
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Cessation of menses
The abrupt cessation of menstruation in a healthy
reproductive-aged woman who previously hasexperienced spontaneous, cyclical, predictablemenses is highly suggestive of pregnancy
Amenorrhea is not a reliable indication of
pregnancy until 10 days or more after expectedmenses onset. When a second menstrual period ismissed, the probability of pregnancy is muchgreater
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Changes in Cervical Mucus
Mucus crystallization necessary for the production of the
fern pattern is dependent on an increased sodium chlorideconcentration.
Cervical mucus is relatively rich in sodium chloride whenestrogen, but not progesterone, is being produced.
From about the 7th to the 18th day of the menstrual
cycle, a fernlike pattern of dried cervical mucus is seen
After approximately the 21st day, a different patternforms that gives a beaded or cellular appearance
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Breast Changes
Anatomical changes in the breasts thataccompany pregnancy are
characteristic during a first pregnancy
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Vaginal Mucosa
During pregnancy, the vaginal mucosausually appears dark bluish or purplish-
red and congested - the so-called
Chadwick sign
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Skin changes
Increased pigmentation and changesin appearance of abdominal striae are
common to, but not diagnostic
of, pregnancy.
They may be absent during
pregnancy, and they may be seen in
women taking estrogen-progestin
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Uterine changes
During the first few weeks of pregnancy, theincrease in uterine size is limited principally to theanteroposterior diameter
By 12 weeks, the body of the uterus is almostglobular, and an average uterine diameter of 8 cm
is attained. At about 6 to 8 weeks' menstrual age, on
bimanual examination a firm cervix is felt whichcontrasts the now softer fundus and compressible
interposed softened isthmus - theHegar sign
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Uterine changes
Uterine souffle may be heard in the later months
of pregnancy, a soft blowing sounf that issynchronous with the maternal pulse, producedby passage of blood through the dilated uterinevessels
Funic souffle sharp, whistling sound that issynchronous eith the fetal pulse, caused by therush of blood through the umbilical arteries
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Cervical Changes
Increased cervical softening as pregnancy
advances
External cervical os and cervical canal may
become sufficienlty patulous to admit the
fingertip, however, the internal os shouldremain close
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Perception of Fetal Movements
May first perceive fetal movements
between 16 and 18 weeks
A primigravida may not appreciate fetal
movements until approximately 2 weeks
later (18-20 weeks) At approximately 20 weeks, depending on
maternal habitus, an examiner may begin
to detect fetal movements
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PregnacyTest Detection of hCG in maternal blood and urine
provides the basis for endocrine tests of pregnancy
HCG is a glycoprotein woth a high carbohydrate content
Composed of and subunits
-subunit is identical to those in LH, FSH andTSH
HCG prevents the involution of the corpus luteum (principal siteof progesterone production for the first 6-weeks
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PregnacyTest With sensitive test the
hormone can be detectedin maternal palsma orurine by 8-9 days after
ovulation
Doubling time = 1.4 2
days
False positive hCG testresults are rare e.g.heterophilic antibodies
Serum hCG l evel s increase from t heday of impl antation and reach peak l evel s at 60-70days. T hereafter, t heconcentration decl ines sl ow l y unti l
a nadir at about 16 weeks.
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A gestational sac may be demonstrated by
abdominal sonography after only 4 to 5
weeks menstrual age. By 35 days, a normal sac should be visible in
all women
After 6 weeks, heart motion should be seen
Up to 12 weeks, the crown-rump length ispredictive of gestational age within 4 days
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Prenatal care should be initiated as soon
as there is a reasonable likelihood of
pregnancy.The major goals are to: Define the health status of the mother and
fetus
Estimate the gestational age
Initiate a plan for continuing obstetricalcare.
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WEEKS
FirstVisit 15-20 24-28 29-41
History
y Complete *
y Updated * * *
Physical
Examination
y Complete *
y BP * * * *
y Maternal
Weight
* * * *
y Pelvic/Cervical
Exam
*
y Fundal Height * * * *
y Fetal HeartRate/Position
* * * *
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WEEKS
FirstVisit 15-20 24-28 29-41
Laboratory Test
y Hct or Hgb y * y *
y Blood type & Rh
factor
y *
y Antibody screen y * A
y Pap smear
screen
y *
y Glucose
tolerance test
y *
y Fetal Aneuploidy
ScreeningBa and/or B
y NeuralTube
defect screeningB
y Cystic Fibrosis
screeing
B or B
y Urine proteinassessment
*
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WEEKS
FirstVisit 15-20 24-28 29-41
Laboratory Test
y Urine Culture *
y Rubella
serology
*
y Syphilis
serology
* C
y Gonococcal
culture
D D
y Chlamydial
culture
y * C
y Hepatitis B
serology
y *
y HIV serology B
y Group
B
strepculture E
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a First-trimester aneuploidy screening may beoffered between 11 and 14 weeks
A Performed at 28 weeks, if indicated B Test should be offered C High risk women should be retested at the
beginning of the third trimester D High risk women should be screened at the first
prenatal visit and again in the third trimester E Rectovaginal culture should be obtained
between 35 and 37 weeks
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Use of a standardized recod with a perinatal
healthcare system greatly aids antepartum
and intrapartum management. Standardizing documentation may allow
communication and continuity of carebetween providers and enable objective
measures of care quality to be evaluated overtime and across different clinical setting.
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There are several definitions pertinent to establishment of an accurate prenatal record:
Null igravida: a woman who currently is not pregnant, nor
has she ever been pregnant Gravida: a woman who currently is pregnant or she has
been in the past, irrespective of the pregnancy outcome.With the establishment of the first pregnancy, shebecomes a primigravida, and with successive pregnancies,a mul tigravida
Null ipara: a woman who has never completed a pregnancybeyond 20 weeks' gestation. She may or may not havebeen pregnant or may have had a spontaneous or elective
abortion(s) or an ectopic pregancy
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There are several definitions pertinent to establishment of an accurate prenatal record:
Primipara: a woman who has been delivered only once of a fetus
or fetuses born alive or dead with an estimated length of gestation of 20 or more weeks. In the past, a 500-g birthweight
threshold was used to define parity.This threshold is no longeras pertinent because of the survival of infants with birthweights
less than 500 g.
Mul tipara: a woman who has completed two or morepregnancies to 20 weeks or more. Parity is determined by thenumber of pregnancies reaching 20 weeks and not by the
number of fetuses delivered. Parity is the same (para 1) for a
singleton or multifetal delivery or delivery of a live or still born
infant
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In some locales, the obstetrical history issummarized by a series of digits connected
by dashes.T
hese usually refer to the number of term infants, preterm infants,
abortus less than 20 weeks, and children
currently alive. (F-P-A-L)
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The mean duration of pregnancy calculated from the firstday of the last normal menstrual period is very close to 280 days, or 40 weeks
It is customary to estimate t
he expected date of de
l ivery by adding 7 days to t he date of t he first day of t he l ast normal
menstrual period and counting back 3 mont hs (Naegeles rule).
A gestational age or menstrual age calculated in this way
erroneously assumes pregnancy to have begun approx. 2
weeks before ovulation. Use to mark temporal events inpregnancy
Ov ulatory age or fertilization age employed byembryologist and other reproductive biologist, which are
typically 2 weeks shorter.
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It has become customary to divide pregnancyinto three equal epochs of approx. 3 calendar
months. Historically, the first trimesterextends through completion of 14 weeks,
sthe second through 28 weeks, and the third
includes the 29th through 42nd weeks of
pregnancy. Thus, there are three periods of 14 weeks
each
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Certain major obstetrical problems tend to cluster ineach of these time periods.
Most spontaneous abortions take place during the first
trimester
Most women with hypertensive disorders due topregnancy are diagnosed during the third trimester
Because precise knowledge of fetal age is
imperative for ideal obstetrical management, theclinically appropriate unit is weeks of gestationcompleted, and more recently, clinicians designategestational age using completed weeks and days.
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Detailed information concerning past obstetrical history iscrucial because many prior pregnancy complications tend torecur in subsequent pregnancies
The menstrua
l h
istory is extremely important.T
he womanwho spontaneously menstruates regularly every 28 days orso is most likely to ovulate at midcycle.Thus, the gestationalage (menstrual age) becomes simply the number of weekssince the onset of the last menstrual period.
Without a history of regular, predictable, cyclic, spontaneousmenses that suggest ovulatory cycles, accurate dating of pregnancy by history and physical examination is difficult.
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The American College of Obstetricians andGynecologists advocate psychosocial screening atleast once each trimester to increase the likelihood
of identifying issues and reducing adversepregnancy outcomes.
Screening ofr barriers to care includes lacktransportation,child care or family support; unstable
housing, unintended pregnancy, communicationbarriers, nutritional problems, cigarette smoking,subtance abuse, depression and safety concernsthat include domestic violence.
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Smoking results in unequivocal adversesequelae for pregnant women and their
fetuses. Numerous adverse outcomes have been
linked to smoking during pregnancy
There is a twofold risk of placenta previa,
placental abruption and prematuremembrane rupture compared with non-smokers.
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Babies born to women who smoke areapprox. 30% more likely to be born preterm,
weigh on average a half pound less, and areup to three times more likely to die of SIDS.
Pathophysiological cause:
Fetal hypoxia (increase carboxyhemoglobin)
Reduced uteroplacental blood flow
Direct toxic effects of nicotine and other compounds
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The most successful efforts for smoking cessationduring pregnancy involve interventions thatemphasize how to stop.
One example is a 5-step session lasting 15 minutesor less in which the provider:
(1) Asks about smoking status;
(2) Advises those who smoke to stop;
(3) Assesses the willingness to quit within the next 30 days;
(4) Assists interested patients by providing pregnancy-specific self-help materials; and
(5) Arranges follow-up visits to track progress
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The American College of Obstetricians and
Gynecologists (2005b) has concluded that it is
reasonable to use nicotine medicationsduring pregnancy if prior nonpharmacological
attempts have failed
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Ethanol is a potent teratogen and causes thefetal alcohol syndrome, which is
characterized by growth restriction, facialabnormalities, and central nervous system
dysfunction
Women who are pregnant or considering
pregnancy should abstain from using anyalcoholic beverages
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It is estimated taht 10 percent of fetuses areexposed to one or more illicit drug
Agents may include heroin and other opiates,cocaine, amphetamines, barbiturates and
marijuana
Well documented sequelae inlcude fetal
distress, low birthweight, and drugwithdrawal soon afetr birth
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Unfortunately, most abused women contibueto be victimized during pregnancy
Domestic violence is more prevalent than anymajor medical condition detectable through
routine prenatal screeining
Intimate partner violence is associated with
an increase risk of a number of adverseperinatal outcomes including pretermdelivery, fetal-growth restriction, and
perinatal death
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A thorough, general physical examination should be
completed at the initial prenatal encounter
The cervix is visualized employing a speculum lubricated
with warm water or water-based lubricant gel Bluish-red passive hyperemia of the cervix is characteristic,
but not of itself diagnostic, of pregnancy
Dilated, occluded cervical glands bulging beneath the
exocervical mucosa, so-called nabot hian cysts, may be
prominent.
The cervix is not normally dilated above the level of the
internal os.
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Leopolds Maneuver LM 1 (Fundal Grip)
What fetal pole or part occupies the fundus? Breech irregular, nodular
Cephalic round
LM2 ( Umbilical Grip)
Which side is the fetal back?
Back linear, convex, bony ridge
Small parts numerous nodulation
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Leopolds Maneuver
LM3 (Pawliks Grip)
What fetal part lies abovbe the pelvic inlet? Head not engaged round, ballotable, easily displaces
Head engaged felt as relatively fixed, knoblike part
LM4 (Pelvic Grip)
Which side the cephalic prominence? Examiner faces the patients feet and places one hand each on either side
of the lower pole of the uterus
Cephalic prominence
x Part of the fetus that prevents the deep descent with one hand
Flexion cephalic prominence same side as fetal parts
Extension same side as the fetal back
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There are many risk factors that can be
identified and given appropriate considerationin pregnancy management
Some conditions may require the involvement
of a maternal-fetal medicine subspecialist,geneticist, pediatrician, anesthesiologist, or
other medical specialist in the evaluation,counseling, and care of the patient
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Asthma
y Symptomatic on medication OBG
y Severe MFM
Cardiac Disease MFM
DM OBG or MFM
Epilepsy (on medication) OBG
Hypertension
y Chronic, with renal and heart disease MFM
y Chronic, without renal and heart disease OBG
Prior fetal death OBG
HIV/AIDS MFM
Multifetal gestation OBG
Preterm Labor,Threatened OBG
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Traditionally, the timing of subsequent
prenatal visits has been scheduled at intervalsof 4 weeks until 28 weeks, and then every 2
weeks until 36 weeks, and weekly thereafter.
Women with complicated pregnancies oftenrequire return visits at 1- to 2-week intervals.
Routine prenatal care, required a median of 8 visits
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At each return visit, steps are taken to
determine the well-being of mother and fetus
Evaluation typically includes:
Fetal
Heart rate(s)
Size - current and rate of change
Amount of amnionic fluid Presenting part and station (late in pregnancy)
Activity
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Evaluation typically includes:
Maternal
Blood pressure - current and extent of change
Weight - current and amount of change Symptoms including headache, altered vision, abdominal pain,
nausea and vomiting, bleeding, vaginal fluid leakage, and dysuria
Height in centimeters of uterine fundus from symphysis
Vaginal examination late in pregnancy often provides valuable
information: Confirmation of the presenting part.
Station of the presenting part
Clinical estimation of pelvic capacity and its general configuration
Consistency, effacement, and dilatation of the cervix.
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One of the most important determinations at
prenatal examinations is assessment of fetalage.
Precise knowledge of gestational age is
important because a number of pregnancycomplications may develop for which optimal
treatment will depend on fetal age
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Between 20 and 34 weeks, the height of the uterine fundus,
measured in centimeters, correlates closely with gestationalage in weeks
The fundal height should be measured as the distance overthe abdominal wall from the top of the symphysis pubis to thetop of the fundus.
12th week above the symphisys pubis
16th week halfway between the symphysis pubis and the umbilicus
20th week level of umbilicus 28th week 6 cm above the umbilicus
36th week 2 cm below the xiphoid
40th week 4 cm below the xiphoid
T he bl adder must be emptied before making t he measurement.
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The fetal heart can first be heard in most women between 16
and 19 weeks when carefully auscultated with a non-amplifiedstethoscope
The fetal heart rate now ranges from 110 to 160 bpm and isheard as a double sound resembling the tick of a watch undera pillow.
Instruments incorporating Doppler UTZ instruments are oftenused to easily detect fetal heart action, almost always by 10
weeks. Using real-time sonography with a vaginal transducer, fetal
cardiac activity can be seen as eraly as 5 menstrual weeks.
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All pregnant women should be screened for
gestational diabetes mellitus, whether byhistory, clinical risk factors, or routine
laboratory testing.
Although laboratory testing between 24 and28 weeks is the most sensitive approach, there
may be pregnant women at low risk who areless likely to benefit from testing
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The American Academy of Pediatrics and the
American College of Obstetricians and
Gynecologists (2002) recommend that
pregnant women with risk factors or
symptoms be cultured for N gonorr hoeae at anearly prenatal visit and again in the third
trimester. Risk factors for gonorrhea are similar for those
for chlamydia.
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Selected screening can be offered based on maternal age,
family history, or the ethnic or racial background of the couple
Examples include testing for :
Tay-Sachs disease for people of Eastern European Jewish orFrench Canadian ancestry;
-thalassemia for those of Mediterranean, Southeast Asian,Indian, Pakistani, or African ancestry;
-thalassemia for people of Southeast Asian or Africanancestry; and
Sickle- cell anemia for people of African, Mediterranean,
Middle Eastern, Caribbean, Latin American, or Indiandescent
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Recommended Ranges of Weight Gain during SingletonGestations Stratified by Prepregnancy Body Mass Index
Weight-for-Height Category Recommended Total Weight Gain
Category BMI Kg Lb
Low <19.8 12.5-18 28-40
Normal 19.8-26 11.5-16 25-35
High 26-29 7-11.5 15-25
Obese >29 7 15
The range for twin pregnancy is 35-45 lb (16-20 kg). Young adolescents (<2 yearsafter menarc he) and African-American women should stri v e for ganins at t he upper
end of t he range. Shorter women (<62 in. or <157cm) should stri v e for gains at t helower end of t he range.
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Disadvantages of excessive maternal weight
gain and fetal macrosomia must be
considered Excessive weight gain - defined as more than
40 lb - correlated closely with fetalmacrosomia
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Cohort studies of children born to
nutritionally deprived women have been
performed and were recently reviewed byKyle and Pichard.
Progeny exposed in mid to late pregnancywere lighter, shorter, and thinner at birth and
they had a higher incidence of subsequentdiminished glucose tolerance, hyeprtension,
reactive airway disease, dyslipidemia, and
coronary artery disease.
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Average total weight loss resulted in an averageretained pregnancy weight of 3 lb or 1.4 kg.
Overall, the more weight gained during pregnancy,the more that was lost postpartum
Interestingly, there is no relationship betweenprepregnancy BMI or prenatal weight gain andweight retention.
Accruing weight with age rather than parity isconsidered the main factor affecting weight gainover time
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Periodically, the Food and Nutrition
Board of the Institute of Medicine (2008)
publishes recommended dietaryallowances, including those for pregnant
or lactating women
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AGE(YEARS) 14-18 19-50
FAT-SOLUBLE VITAMINS
VITAMINA 750 g 770 g
VITAMINDa 5 g 5 g
VITAMINE 15 mg 15 mg
VITAMINK 75 g 90 g
WATER SOLUBLE
VITAMINC 80 mg 85 mg
THIAMIN 1.4mg 1.4 mg
ROBOFLAVIN 1.4mg 1.4mgNIACIN 18 mg 18 mg
VITAMIN B6 1.9 mg 1.9 mg
FOLATE 600 g 600 g
VITAMIN b12 2.6 g 2.6 g
F r the Food d N triti on Boar d o f the I nstit te o f Med ici ne ( 8)
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AGE(YEARS) 14-18 19-50
MINERALS
CALCIUMS 1300 mg 1000 mg
SODIUM 1.5 g 1.5 g
POTASSIUMS 4.7 g 4.7 g
IRON 27 mg 27 mg
ZINC 12 mg 11 mg
IODINE 220 g 220 g
SELENIUM 60 g 60 g
OTHERPROTEIN 71 g 71 g
CARBOHYDRATE 175 g 175 g
FIBERS 28 g 28 g
F r om the Food and N triti on Boar d o f the I nstit te o f Med ici ne ( 8)
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Pregnancy requires an additional 80,000
kcal most are accumulated in the last 20
weeks. To meet this demand a caloric increase
of 100 to 300 kcal per day is
recommended
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Added for the demands for growth and
remodeling of the fetus, placenta,
uterus and breast, as well as increasematernal blood volume
Most hould be supplied from animal
sources such as meat, milk, eggs,cheese, poultry and fish, because they
furnish amino acids in optimal
combinations
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As little as 30 mg of elemental iron, supplied asferrous gluconate, sulfate or fumarate and taken dailythroughout the latter half of pregnancy, provides
sufficient iron to meet the requirments of pregnancyand to protect preexisting iron stores.
The pregnant woman may benefit from 60 to 100 mgof iron per day if she is large, has twin fetuses, beginssupplementation late in pregnancy, takes ironirregularly, or has a somewhat depressed hemoglobinlevel
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The pregnant woman retains about 30 g
of calcium, most of which is deposited in
the fetus late in pregnancy This amount of calcium represents only
about 2.5 percent of total maternal
calcium, most of which is in bone, andwhich can readily be mobilized for fetal
growth
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Severe zinc deficiency may lead to poor
appetite, suboptimal growth, and impaired
wound healing. Profound zinc deficiency may cause dwarfism
and hypogonadism
May also lead to a specific skin disorder,
acrodermatitis enteropat hica, as the result of arare, severe congenital zinc deficiency
Recommended daily intake during pregnancy
is about 12 mg
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The use of iodized salt and bread products is
recommended during pregnancy to offset the
increased fetal requirements and maternalrenal losses
Severe maternal iodine deficiencypredisposes offspring to endemic cretinism,
characterized by multiple severe neurologicaldefects
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More than half of neural tube defects can beprevented with daily intake of 400 g of folic acidthroughout the periconceptional period
Because nutritional sources alone are insufficient,however, folic acid supplementation is stillrecommended
A woman with a prior child with a neural-tibe defectcan reduce the 2-5 percent recurrence risk by morethan 70% with daily 4-mg folic acid supplementrsthe month before conception and during the firsttrimester.
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Dietary intake of vitamin A in the United
States appears to be adequate, and routine
supplementation during pregnancy is notrecommended
A small number of case reports suggest anassociation of birth defects with very high
doses during pregnancy, 10,000 to 50,000 IUdaily.
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These malformations are similar to those
produced by the vitamin A derivative
isotretinoin (Accutane), which is a potentteratogen in humans
Beta-carotene, the precursor of vitamin Afound in fruits and vegetables, has not been
shown to produce vitamin A toxicity.
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The level of vitamin B12 in maternal plasma
decreases variably in otherwise normal
pregnancies This decrease is mostly from a reduction in
plasma transcobalamins and is thusprevented only in part by supplementation.
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For women at high risk for inadequate
nutrition (e.g., substance abuse, adolescents,
and those with multifetal gestations), a dailysupplement containing 2 mg is
recommended.
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The recommended dietary allowance for
vitamin C during pregnancy is 80 to 85
mg/day, or about 20 percent more than whennonpregnant
A reasonable diet should readily provide thisamount.
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More than half of the children in the US are
born to working mothers
Federal law prohibits from excluding womenfrom job categories on the basis that they are
or might become pregnant
In the absence of complications, most
women can continue to work until the onsetof labor
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Occupational fatigue, estimated by the number of hours standing, intensity of physical and mentaldemands, and environmental stressors, was
associated with an increased risk of pretermmembrane rupture
Thus, any occupation that subjects the pregnanctwoman to sever physicl strain should be avoided
Adequate period of rest should be provided
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The American College of Obstetricians and
Gynecologists advises a thorough clinical
evaluation be conducted beforerecommending an exercise program.
In the absence of contraindications, pregnantwomen should be encouraged to engage in
regular, moderate-intensity physical activity30 minutes or more a day
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ABSOLUTE AND REALATIVE CONTRAINDICATIONS TOAEROBIC EXERCISE DURING PREGNANCY
ABSOLUTE CONTRAINDICATIONS
Hemodynamically significant heartdisease
Restrictive lung disease
Incompetent cervix/ cerclage
Multifetal gestation at risk for pretermlabor
Persistent second-or third- trimesterbleeding
Placenta previa afet 26 weeks
Preterm labor during the currentpregnancy
Ruptured membranes
Preeclampsia/ pregnancy- inducedhypertension
RELATIVE CONTRAINDICATIONS
Severe anemiaUnevaluated maternal cardiac arrythmia
Chronic bronchitis
Poorly controlled type 1 diabetes
Extreme morbid obesity
Extreme underweight (BMI <12)
History of extremely sedentary lifestyle
Fetal- growth restriction in currentpregnancy
Poorly controlled hypertension
Orthopedic limitations
Poorly controlled seizure disorder
Poorly controlled hyperthyroidism
Heavy smoker
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Automobile Travel
Pregnant women should be encouraged to wear
properly positioned three-point restraints throughout
pregnancy while riding in automobiles. The lap belt portion of the restraining belt should be
placed under the woman's abdomen and across her
upper thighs.
The belt should be as snug as comfortably possible. The shoulder belt also should be snugly applied and
positioned between the breasts
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It is generally accepted that in healthy
pregnant woman, sexual intercourse ussually
is not harmful. Whenever abortion or preterm labor
threatens, however, coitus should be avoided
Intercourse late in pregnacy specifically has
not been found to be harmful
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LIVE ATTENUATED Indications Dose Schedule Comments
MEASLES Contraindicated Single dose SC, preferably as
MMRa
Vaccinate susceptible women
postpartum.Breast feeding is
not a contraindication
M
M ¡ S Contraindicated Single dose SC, preferably asMMR
Vaccinate susceptible womenpostpartum
R
BELLA Contraindicated, but congenital
rubella syndrome has never
been described after vaccine
Single dose SC, preferably as
MMR
Teratogenicity of vaccine is
theoretical and not confirmed
to date; vaccinate susceptible
women postpartum
¡ OLIOMYELITISORAL= LIVE
ATTENTUATED; INJECTION=ENHANCED-
¡ OTENCY
INACTIVATEDVIRUS
Not routinely recommended
for women in theUnited States,except women at increased risk
for exposure
¡ rimary:Two doses of
enhanced-potency inactivatedvirus SC at 4-8 week intervals
and 3rd dose 6-12 months after
2nd doses
Vaccine indicated for
susceptible women traveling
VARICELLA Contraindicated, but not
adverse outcomes repoted in
pregnancy
Two doses needed: 2nd dose
given 4-8 weeks after 1st dose
Teratogenicity of vaccine is
theoretical.Vaccination of
susceptible women should be
considered postpartum.
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INACTIVATED BACTERIAL VACCINES
Indications Dose Schedule Comments
PNEUMOCCOCUS Indications not altered by
pregnancy. Recommended
for women with asplenia;metabolic, renal, cardiac, or
pulmonary diseases;
immunosuppression; or
smokers
In adults, one dose only;
consider repeat dose in 6
years for high-rik women
Polyvalent polysaccharide
vaccine
MENINGOCOCCUS Indications not altered by
pregnancy; vaccination
recommended in unusual
outbreaks
One dose, tetravalent
vaccine
Antimicrobial prophylaxis if
significant exposure
THPHOID Not recommended Killed Primary: 2 injections
IM 4 weeks apart
Booster: One dose:
scheduled
Killed, injectable vaccine or
live attentuated oral vaccine.
Oral vaccine preferred.
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TOXOID Indications Dose Schedule Comments
TATANUS-DIPTHERIA Lack of primary series,
or no booster within
pat 10 years
Primary:Two doses IM
at 1-2 month interval
with 3rd dose 6-12 months after the 2nd
Booster: Single dose IM
every 10 years after
completion of primary
series
Combined tetanus-
diptheria toxoids
preferred: adultstetanus-diptheria
formulation. Updating
immune status should
be part of antepartum
care.
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SPECIFIC IMMUNE
GLOBULINS
Indications Dose Schedule Comments
HEPA B Postexposure prophylaxis Depends on exposure Usually given with Hepa B
virus vaccine; exposednewborn needs immediate
prophylaxis
RABIES Postexposure prophylaxis Half dose at injury site, half
dose in deltoid
Used in conjugation with
rabies killed- virus vaccine
TETANUS Postexposure prophylaxis One dose IM Used in conjugation with
tetanus toxoid
VARICELLA Should be considered for
exposed pregnant women
to protect against
maternal, not congenital,
infection
One dose IM within 96
hours of exposure
Indicated also for
newborns or women who
developed varicella within
4 days before delivery or 2
days following delivery
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In 1980, the FDA advised pregnant women to limit caffeine
intake. The Fourth International Caffeine Workshop concluded
shortly thereafter that there was no evidence that caffeinecaused increased teratogenic or reproductiverisks
In small laboratory animals, caffeine is not a teratogen, but if
given in massive doses it potentiates mutagenic effects of radiation and some chemicals.
The American Dietetic Association (2002) recommends thatcaffeine intake during pregnancy be limited to less than 300 mg daily, or about three, 5-oz cups of percolated coffee.
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These are common complaints during the
first half of pregnancy.
Although they tend to be worse in themorning, thus, erroneously called morning
sickness, symptoms usually commencebetween the first and second missed
menstrual period and continue until about 14 to 16 weeks.
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Although nausea and vomiting tend to be
worse in the morning, they may continue
throughout the day. Fortunately, the unpleasantness and
discomfort usually can be minimized. Eatingsmall feedings at more frequent intervals but
stopping short of satiation is of value.Thesmell of certain foods often precipitates or
aggravates the symptoms and should be
avoided.
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Low back pain to some extent is reported in nearly70 percent of pregnant women
Minor degrees follow excessive strain or fatigue and
excessive bending, lifting, or walking. Back pain can be reduced by having women squat
rather than bend over when reaching down,providing back support with a pillow when sitting
down, and avoiding high-heeled shoes.
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These enlarged veins generally result fromcongenital predisposition and are exaggerated byprolonged standing, pregnancy, and advancing age
Become more prominent as pregnancy advances, asweight increases, and as the length of time spentupright is prolonged.
The treatment of varicosities of the lower
extremities is generally limited to periodic rest withelevation of the legs, elastic stockings, or both.
Surgical correction is not advised
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Their development or aggravation during pregnancyundoubtedly is related to increased pressure in therectal veins.
This is caused by obstruction of venous return bythe large uterus as well as by constipation duringpregnancy.
Pain and swelling usually are relieved by topically
applied anesthetics, warm soaks, and stool-softening agents.
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One of the most common complaints of pregnant women
and is caused by reflux of gastric contents into the loweresophagus
Most likely results from the upward displacement andcompression of the stomach by the uterus, combined withrelaxation of the lower esophageal sphincter
Are relieved by a regimen of more frequent but smallermeals and avoidance of bending over or lying flat.
Antacid preparations may provide considerable relief. Aluminum hydroxide, magnesium trisilicate, or magnesium
hydroxide alone or in combination are given.
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The cravings of pregnant women for strange foodsare termed pica
There has been considerable historical interest in
the cravings (pica) of pregnant women for strangefoods and, at times, nonfoods such as ice(pagophagia), starch (amylophagia), or clay(geophagia).
This desire has been considered by some to betriggered by severe iron deficiency.
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Women during pregnancy are
occasionally distressed by profuse
salivation. The cause of this ptyalism sometimes
appears to be stimulation of the salivary
glands by the ingestion of starch.
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Beginning early in pregnancy, many women experiencefatigue and need increased amounts of sleep
Likely due to soporific effect of progesterone
Fatigue and nonrestful sleep may be exacerbated bymornig sickness
By the late 2nd trimester, total nocturnal sleep isdecerased, and women usuually begin to complain of
sleep distrubances By the third trimester, nearly all women have altered
sleep Daytime naps and mild sedatives at bedtime such as
diphenhydramine are usually helpful
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Pregnant women commonly develop increasedvaginal discharge, which in many instances is notpathological.
Increased mucus secretion by cervical glands inresponse to hyperestrogenemia is undoubtedly acontributing factor.
Occasionally, troublesome leukorrhea is the result
of an infection caused by trichomonal or yeastvulvovaginal infections.
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CordLife collects, processes and stores your baby's cord
blood stem cells which may later become potential sourcematerial for lifesaving treatment.
T
here is only one chance to collect, which is at birth of yourbaby.
Cord blood has become a major source of stem cells for
transplantation worldwide and is used to treat over 80 diseases, including certain cancers and bone marrow failure
syndromes, inborn errors of metabolism, blood disordersand immunodeficiencies.
Stem cells are also showing great promise in the treatment
of neural injury, diabetes, heart conditions.
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