program updates · (in part) by r13 ca136301 from the national cancer institute. the views...

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Program Updates The following changes were made after the program book went to press. The below list may not reflect the most recent updates. Please visit APSA’s 10th Annual Meeting (http://www.physicianscientists.org/?page=10thAnnualMeeting) webpage for the most up-to-date schedule. Location Change Grant-Writing for the Post-Graduate Physician-Scientist Trainee will take place Thursday, April 24th at 5:00 PM in the Crystal Room. Residency Luncheon (Sunday, April 27th at 12:30 PM) additional programs: National Institutes of Health (NIH) Residency and Fellowship Training Programs Yale University - Internal Medicine Research Pathway

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Page 1: Program Updates · (in part) by R13 CA136301 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators

Program UpdatesThe following changes were made after the program book went to press. The below list may not reflect the most recent updates. Please visit APSA’s 10th Annual Meeting (http://www.physicianscientists.org/?page=10thAnnualMeeting) webpage for the most up-to-date schedule.

Location Change

Grant-Writing for the Post-Graduate Physician-Scientist Trainee will take place Thursday, April 24th at 5:00 PM in the Crystal Room.

Residency Luncheon (Sunday, April 27th at 12:30 PM) additional programs:

• National Institutes of Health (NIH) Residency and Fellowship Training Programs• Yale University - Internal Medicine Research Pathway

Page 2: Program Updates · (in part) by R13 CA136301 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators
Page 3: Program Updates · (in part) by R13 CA136301 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators

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10th Annual American Physician Scientists Association(APSA) Conference

In association with:the American Society for Clinical Investigation (ASCI) and

the American Association of Physicians (AAP)

April 25-27, 2014The Fairmont Hotel

Millenium ParkChicago, Illinois, USA

Table of ContentsAnnual Meeting Committee Welcome 2

Presidential Update 3

Founder Letter 5

Annual Meeting Gratitude 6

Awards 10

Social Events 13

Thursday, April 24 and Friday, April 25 Schedule 14

Saturday, April 26 Schedule 17

Sunday, April 27 Schedule 20 Speaker Biographies 22 Interest Group Mentors 40 List of Participants 43

APSA Announcements 52

Map of the Fairmont Hotel 53

Ruby (up to $1,000)

Bronze ($3,000+)

Platinum ($20,000+)

APSA gratefully acknowledges the following organizations for their sponsorship of the 10th Annual Meeting. Sponsors help make the APSA Annual Meeting possible through financial contributions, sponsorship of speakers, and support of mentorship activities.

Funding for the APSA Annual Meeting (2009-2014) is made possible (in part) by R13 CA136301 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorse-ment by the U.S. Government.

Gold ($10,000+)

Silver ($5,000+)

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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APSA 2014 Annual Meeting Committee Welcome

Colleagues, Mentors, and Friends,

We want to welcome you all to the 10th Annual Meeting of the American Physician Scientists Association (APSA)! We are thrilled to continue the tradition of holding this meeting jointly with the American Society for Clinical Investigation and the Association of American Physicians (ASCI/AAP), and in conjunction with the meeting for the Central Society for Clinical and Translational Research and the Midwestern Section of the American Federation for Medical Research (CSCTR/MWAFMR).

On behalf of APSA, ASCI/AAP, and CSCTR/MWAFMR, we are elated to bring you a lineup of stellar keynote speakers, informative breakout sessions, educational workshops, and numerous opportunities to network with other physician-scientists and physician-scientist trainees.

The APSA/ASCI/AAP meeting described in this booklet is held at the Fairmont Chicago Millennium Park. The CSCTR/MWAMFR meeting, which all APSA registrants are welcome and encouraged to attend, is held at the Renaissance Blackstone Chicago Hotel (636 South Michigan Avenue). This venue is within walking distance of the Fairmont and takes place from Thursday April 24th through Friday April 25th—for full schedule of events please visit www.cscr.com/am14

We hope that you will be able to take full advantage of all the educational opportunities during this weekend. Our entire committee has worked tirelessly to organize this amazing program. Our speaker selection was based upon not only their work in their respective fields but their role in mentorship in training the next generation; furthermore, we have asked them to address the theme of this year’s APSA annual meeting: Physician Scientists in the 21st Century. We hope that you will utilize these amazing opportunities to learn about and plan for the variety of careers available to physician-scientists. Lastly, we have added a few exciting changes this year, including additional panel discussions and an interest group session on Sunday.

On behalf of the Annual Meeting Committee, we thank you for participating in our 10th annual meeting and hope your attendance brings you a wonderful intellectual, professional, and personal experience.

Best wishes and welcome to Chicago!

Daniel DelloStritto & Sherry Cai Wen

APSA Annual Meeting Committee, Co-Chairs

APSA 2014 Presidential UpdateDear Members, Colleagues, and Friends

Welcome to APSA’s 10th Annual Meeting. We are thrilled to offer you one of the most exciting programs in APSA’s history. In addition to the remarkable programming this year, our 10th meeting will be dedicated to “Physician-scientists in the 21st century,” focusing on unique collaborations, innovative techniques, and ground-breaking approaches, all meant to usher in a new era of productivity and discovery within the fields of translational research and clinical investigation.

This has been a year of tremendous growth and development for the American Physician Scientists Association (APSA) and has been one of the most successful in APSA’s 10 year history. With the support of an expanded and conscientious Executive Council, a productive and supportive Board of Directors led by Eve Geneva, and a new Advisory Council designed to usher in an era of even greater APSA outreach and financial development, APSA has made significant strides in its infrastructure and capacity to expand in the coming years.

Our Membership Committee, under the leadership of Lauren Huckaby, has worked tirelessly to enhance our membership numbers, with our membership at nearly 1300 members with 25 institutional members – the most in APSA’s history. The APSA Institutional Representative (IR) program has also flourished, with 25 new IRs added in just this year alone. Our undergraduate liaisons, resident liaison, and MD-DO member-at-large have launched and analyzed surveys to better understand the needs of our members. We are now implementing programming specifically for these member types and have communicated with pre-health programs, medical schools, and residency programs across the country.

Through the tireless work of APSA’s Public Relations Committee, we have seen some of the greatest successes of the past year. Our website now includes an APSA history page and timeline, exhibiting APSA’s successful path over the past decade, updated committee descriptions, monthly committee updates compiled in brief articles each month, a new comprehensive advertising site for potential sponsors, and the relaunch of APSA’s MD/PhD and research-friendly residency program databases. APSA has conducted multiple Interest Group sessions through live video chat, the last of which included a discussion of translational research by Dr. Barry Coller from the Rockefeller University. We have engaged over 3000 members through facebook, Linkedin, and twitter, with new fans participating in our social media advertising each day. For the first time at the 10th Annual Meeting, Chicago media outlets will be present to capture the importance of this event for trans-lational research and communicate this story to the general public

APSA’s Partnership Committee was created this year to organize and expand our outreach to other scientific and clinical organizations. We formed new collaborations with a number of organizations, including those in dermatology, pathology, gastroenterology, pediatrics, neurology, and strengthened our existing partnerships in infectious diseases, emergency medicine, and radiology. We also benefited from a new partnership with the Lasker Foundation, the Doris Duke Charitable Foundation, and expanded partnership from the Burroughs- Wellcome Fund.

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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A number of initiatives within the Policy Committee have come to fruition in the past year. The Tomorrow’s Physician Initiative is nearing the publication phase and is approaching submission, and many other survey studies are in preparation or analysis now. Through our collaboration with the Association for Clinical and Translational Science (ACTS), we were able to offer free registration to the ACTS Annual Meeting and support our members in their Capitol Hill lobby day.

Our four regional meetings this past fall engaged over 600 trainees across the country to discuss career development, present their latest work, and network with other physician-scientists in training. At these meetings, focus groups with residents and undergraduate students were held to provide feedback on how APSA can better serve these member groups. Undergraduate-and resident-specific panel sessions were held at several meetings helped undergraduates navigate the MD-DO/PhD application process. This committee is also actively working to establish local chapters across the country, which will provide trainees access to events on a local level that are supported by APSA or that reflect the mission of the organization.

Through the efforts of the Finance Committee and Board of Directors, we approved APSA’s first budget, providing financial transparency and accountability in our expenditures. We expanded financial agreements with a number of partners and sought corporate funding from several companies in industry. We will soon launch a campaign to garner support for APSA through crowd-sourcing, which will carry our message to the general public.

We are pleased that our 10th Annual Meeting will be one of the most exciting to date. Our speaker list, and that of ASCI and AAP, reflects the world’s leading physician-scientists, with Nobel laureates and Lasker awardees in their ranks. We designed an innovative small group curriculum, with panels aimed at improving physician-scientists’ outreach to the community and a focus on global health, among others. Our Welcome Reception, which will be held on the 95th floor of the John Hancock Center, is sure to provide an unparalleled view of the Chicago skyline. With an even stronger collaboration with ASCI and AAP and much cross-promotion of our meetings, APSA’s 10th Annual Meeting is sure to be enjoyable and memorable for all in attendance.

Thank you for your support in making this a successful year for APSA. It is your commitment to APSA that allows this organization to flourish and helps to usher in the next generation of physician-scientist trainees. We look forward to continued expansion of our member benefits and to creating innovative ways to effect positive change within the scientific community. If you have any suggestions on ways in which we can improve your career development and offer new educational or networking opportunities, please contact me at [email protected]. The past decade has seen the birth and development of APSA as an entity dedicated to physician-scientist trainees, and we look forward to another decade of advocacy for trainees engaged in translational research and medicine.

Sincerely,

Evan Noch, MD, PhD

President, American Physician Scientists Association

10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

APSA’s Founder’s ReflectionWelcome to the American Physician Scientists Association’s 10th Annual Meeting! It is hard to believe that over a decade has passed since the founding of APSA, which was started to build a community for physician-scientist trainees and to support them throughout their training. APSA was created in a time when there were serious con-cerns about the survival of the endangered “physician-scientist” and when trainees often pursued their training within the silos of their respective institutions. During its first year, the founding members spent an extensive period of time brainstorming and consulting with current physician-scientist trainees, leading physician-scientists, program directors, and other stakeholders in the physician-scientist community from across the country on the purpose and role APSA should have. The founders recognized the need for and supported the wide diversity of training pathways available to support the large spectrum of the physician-scientist workforce needed to bridge the gap between the basic sciences and clinical medicine.

One of APSA’s initial goals was to provide venues, such as meetings and online forums, to bring together trainees with similar interests across institutions. The APSA Annual Meeting held with the American Society for Clinical Investigation and the Association of American Physicians has taken many evolutions over the years and has become the premier and largest meeting to bring together physician-scientist trainees from every stage of training from the undergraduate student, to the medical/graduate student, to the resident/fellow, but to also bring together trainees with successful physician-scientist leaders from across the country. This unique meeting facilitates both horizontal and vertical mentoring and networking opportunities. Shortly after APSA’s 1st Annual Meeting in 2005, APSA quickly expanded its programing with the establishment of regional meetings in New York, Texas, and California.

In addition to its meetings, APSA became a central resource for those interested in pursuing the physician-scientist career through its website, online discussion forums, and outreach activities at undergraduate institutions and pre-med meetings. Within a short time frame, APSA continued to build on its core mission through the development of meetings, co-hosting sessions with partner organizations, working with other professional organizations, advocating on behalf of physician-scientist trainees, and cultivating the creation of similar organizations internationally. As APSA became known as the organization for physician-scientist trainees, APSA took on the role to actively advo-cate for them and the physician-scientist career path by raising more awareness of the issues facing trainees, and by directly addressing the issues through APSA’s activities and its advocacy efforts.

In its short history, APSA has had a wide-ranging and positive impact on the recruitment and retention of physician-scientists through its programming, meetings, resources, and advocacy efforts. APSA serves as a central voice dedicated to the support of physician-scientist trainees. As APSA continues to evolve, it must continue to build and strengthen the community of physician-scientist trainees, stay current with the needs and issues of trainees, provide ways to facilitate the mentoring and support of trainees, and serve as the overall voice for physician-scientist trainees.

Sincerely,

Freddy Nguyen, MD-PhD Candidate

Founder, American Physician Scientists Association

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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APSA would like to thank the following members of the Executive Council for their leadership and support in planning this meeting.

Evan Noch President Weill-Cornell Medical Center Dania Daye Past President University of Pennsylvania Michael Guo President-Elect University of Florida Steven Back Vice President, External Affairs Temple University Stephanie Jackson Vice President, Internal Affairs Saint Louis University Chair, Partnerships Committee Kate Hartmann Chair, Events Committee The Ohio State University

Stephen Chrzanowski Chair, Finance Committee University of Florida Lauren Huckaby Chair, Membership Committee Temple University

Jennifer Kwan Chair, Policy Committee University of Illinois-Chicago Karen Howard Chair, Public Relations Committee SUNY Upstate Medical College Taylor Heald-Sargent Member-at-Large DO-MD/PhD Loyola University

Alvin Das Member-at-Large, MD/DO Northeast Ohio Medical University Maxwell Rogoski Member-at-Large University of Pennsylvania Social Science & Humanities

Eli Levin Resident Liason Northside Hospital, Florida

Sofia Campos Undergraduate Liason University of California, San Diego

Leanne Dumeny Undergraduate Liason University of Florida

10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

Sherry Wen Co-Chair, Annual Meeting Vanderbilt University

Krishna Sarma Vice-Chair, Events Committee University of Nebraska Annual Meeting- Panels Medical Center

Robert Wysocki Vice-Chair, Membership Stony Brook University Committee

Carolyn Brokowski Vice-Chair, Policy Commitee Yale University Peter Mittwede Vice-Chair, Public Relations University of Mississippi Comittee-News

Arjun Sehgal Vice-Chair, Public Relations Texas Tech University Committee-Social Media

Alexander Adami Vice-Chair, Public Relations Connecticut Health Center Committee-Website

Diane Kuhn Vice-Chair, Member-at-Large Johns Hopkins Humanities& Social Sciences

APSA would like to extend a sincere thank you to the following leadership & administration for their enthusiastic and never-ending

assistance in making this joint meeting a reality:

ASCI Sherwood Group Peter Tontonoz, MD, PhD (President) Diane Rutherford (APSA Executive Director) John Hawley (Executive Director) Lyn Maddox Kim Santos

AAP J. Larry Jameson, MD, PhD (President) Lori Ennis (Executive Director)

Daniel DelloStritto Co-Chair, Annual Meeting Northeast Ohio Medical University

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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The APSA Executive Council would like to thank the following members of the Board of Directors for their dedication to the advancement of

APSA and physician-scientists in training:

Ivayla Geneva, PhD, Chair; State University of New York-Upstate

Jaimo Ahn, MD. PhD; University of Pennsylvania

Evan Noch, MD, PhD; Weill-Cornell Medical Center

Michael Guo; University of Florida

Hans Arora, MD, PhD; Cleveland Clinic

Jill Baren, MD; University of Pennsylvania

David Braun, MD, PhD; Brigham and Women’s Hospital

Oscar Cuzzani, MD, PhD; Abbott Labs, Allergan Inc.

Shwayta Kukreti, MD, PhD; UCLA

Moshe Levi, MD; University of Colorado

David Markovitz, MD; University of Michigan

Juanita Merchant, MD, PhD; University of Michigan

M. Kerry O’Banion, MD, PhD; University of Rochester

Eric Schauberger, DO, PhD; Medical College of Wisconsin/Children’s Hospital

Michael Zasloff, MD, PhD; Georgetown University

10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

The APSA Executive Council would like to thank the following members of the Advisor Council for their dedication to the strategic planning and

development for the APSA organization:

Richard B. Gaynor, MD; Eli Lilly

Fabio Gratton; Sonic Health

William N. Kelley, MD; University of Pennsylvania

Jason Mills, MD, PhD; Washington University

Roger Pomerantz, MD; Seres Health

APSA would like to thank the members of the Annual Meeting Committee for their tremendous support, guidance, and tireless leadership in planning this meeting

Kate Hartmann Chair, Events Committee Sherry Wen Co-Chair, Annual Meeting

Daniel DelloStritto Co-Chair, Annual Meeting Krishna Sarma Vice-Chair, Panels

Adrienne Barry Vice-Chair, Residency Greg Botta Committee Member Luncheon Irene Chernova Committee Member Davide Cina Committee Member

Stephanie Brosius Committee Member Edita Klimyte Committee Member

Keon-young Park Committee Member Aisha Siebert Committee Member Shrey Sindhwani Committee Member Anisley Committee Member Valenciaga Jennifer Stanley Committee Member

Danelle Desjardins Committee Member

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

APSA Abstract Travel Awards ($500 each)

Yohance M. Allette Kathryn E. HackerIndiana University School of Medicine University of North Carolina at Chapel Hill

Jackeline J. Rodriguez-Smith Matthew M. SheehanNational Institute of Arthritis and Boston Children’s Hospital/ Harvard MedicalMusculoskeletal and Skin Diseases School

Brandon B. Holmes Emily J. AnstadtWashington University in Saint Louis University of Connecticut Health Center

Javier Cabrera-Perez Bianca N. IslamUniversity of Minnesota Georgia Health Sciences University

Kavisha Singh Eileen S. CarpenterDuke University SUNY Stony Brook

Cymon N. Kersch Emily A. SlatOregon Health and Science University Washington University in Saint Louis

Hsiang-Chun Chang Priya PalNorthwestern University Washington University in Saint Louis

Jennifer A. Stanley David Y. ChiangUniversity of Alabama at Birmingham Baylor College of Medicine

James J. Park Daniel TalmasovLoyola University Stony Brook University

Jeffrey R. Gehlhausen Jennifer RhaIndiana University School of Medicine Emory University

Nicholas A. Taylor Robert L. TrevinoUniversity of North Carolina at Chapel Hill Rush University Medical Center

Cesar A. Virgen Reid WilkeningUniversity of California San Diego University of Illinois at Chicago

Maria C. Trissal Alice N. WeaverWashington University in Saint Louis University of Alabama at Birmingham

Jaime E. ZelayaOregon Health and Science University

AAI Awards ($200 each)Andrew Cox Andrew JonesUniversity of Rochester Saint Louis University

Nicole Kretzer Jason MeyerWashington University University of Kentucky

Maria ThemeliMemorial Sloan-Kettering Cancer Center

ASIP/ICPI Pathology Award ($750)Teerawit SupakorndejWashington University

SAEM Awards ($500 each)Douglas Bennion Cindy HsuUniversity of Florida University Of Pennsylvania

Anh Nguyen Eric PedoneUniversity of North Texas Loyola University

Pascal PfiffnerHarvard University

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

Local Chapter Awards

University of Alabama-BirminghamUniversity of KentuckyOhio State College of Medicine

International Travel Awards

Raphaël Bernard-Valnet Association of Medical/Pharmaceutical Sciences (AMPS)

Kevin Wang Clinician Investigator Trainee Association of Canada (CITAC)

Laurence Feldmeyer Swiss MD-PhD Association (SMPA)

Dipan UppalAsian Medical Students’ Association International (AMSA International)

APSA Directors’ Award

Freddy NguyenUniversity of Illinois at Urbana-Champaign

Meeting Highlights- Social Events

Friday Night Dinner OutingsNot from Chicago originally? Not sure where to go for dinner or whom to go with? APSA is here to help! Sign up at the registration desk outside the International Ballroom for group dinner reservations. Pick from a variety of restaurants that have been hand-selected by our Annual Meeting Committee. We’ve already made the reservations and printed out direc-tions. All you need to do is sign up and meet some new-found APSA friends in the lobby of the Fairmont at 7pm.

Friday Night Welcome ReceptionAfter a casual dinner out on the town, come and mingle with fellow physician-scientists in training on the 95th floor of the Hancock Center. Enjoy music, drinks, dancing, and a Pres-idential Address from Evan Noch. And of course, enjoy the spectacular view of the Windy City. Shuttles will go back and forth between the Fairmont (lower level) and the Hancock Center throughout the evening.

Saturday Night DinnerPrepare to dust off those fancy clothes you never get to wear and join us for the APSA Dinner on Saturday night (black tie optional). Our keynote speaker will be Dr. Paul Offit, physician, scientist, trailblazer in the field of vaccine research and development. Come and join us for an evening of food, conversation, and what promises to be a fascinating talk on the bench-to-bedside world of vaccine research.

Don’t forget to share your favorite moments of this special 10th Annual Meeting on Facebook, Linkedin, and Twitter!

Be on the lookout for special giveaways during the 10th Annual Meeting!

You could win your very own APSA poster carrier!

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

Friday, April 25thTime Event Location

8:30 am - 10:45 am APSA Business Meeting Moulin Rouge8:30 am - 8:35 am Board of Directors Welcome Message Eve Geneva, Chair, APSA Board of Directors, MD/PhD Candidate, SUNY Upstate

8:35 am – 8:50 am Opening Remarks Evan Noch, MD, PhD, President, APSA, Weill-Cornell Medical College-New York Presbyterian Hospital

8:50 am - 9:30 am APSA Standing Committee Reports Policy, Finance, Public Relations, Membership, and Events

9:30 am – 9:45 am APSA Executive Council Candidate Speeches & Voting

9:45 am – 10:00 am American Medical Women’s Association (AMWA) presentation

10:00 am - 10:15 am Local Chapter Presentations University of Alabama-Birmingham

University of Kentucky Ohio State University

10:15 am – 10:30 am International Partner Panel Association of Medical/Pharmaceutical Sciences (AMPS), Clinician Investigator-Trainee Association of Canada (CITAC), Swiss MD-PhD Association (SMPA), Asian Medical Students’ Association International (AMSA)

10:30 am – 10-45 am Closing Remarks Michael Guo, President-Elect, MD/PhD Candidate, University of Florida

11:00 am - 11:45 am APSA Keynote International Ballroom Mark Courtney, MD, Northwestern University SAEM Sponsored Talk 12:00 pm - 12:45 pm APSA Keynote Brian Kobilka, MD, International Ballroom Stanford University

1:00 pm - 3:00 pm Poster Setup Imperial Ballroom 1:00 pm - 6:15 pm Plenary Session I: Understanding International Ballroom Disease Mechanisms to Improve Human Health

1:00 pm – 1:30 pm Genomics and the future of International Ballroom diagnosis, prevention, and therapeutics Richard P. Lifton, MD, PhD, Yale University

1:30 pm – 2:00 pm Close to the bone: Novel genes International Ballroom that remodel the skeleton Laurie H. Glimcher, MD, Weill Cornell Medical College 2:00 pm - 3:00 pm APSA Panel: The Intertwining Crystal Room Growth of Women and Medicine in the 21st Century Panelists: Amy Y. Chen, MD; Amy H. Kaji, MD, PhD Usha Raj, MD ; Moderator Ivayla Geneva

Thursday, April 24thTime Event Location

5:00 pm - 6:30 pm Grant-writing for the post-graduate Imperial Ballroom physician-scientist trainee: a practical approach to fellowship funding and beyond José Cavazos, Director, MD/PhD Program, UTHSC-San Antonio (RSVP required to [email protected])

9:00 pm - 11:00 pm Social Event with CSCTR and MWAFMR Meet at Mercat a la Planxa, the bar/restaurant in the Renaissance Blackstone hotel Opportunity for APSA members to network with members of CSCTR and MWAFMR

Meeting Agenda

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

2:00 pm - 3:00 pm ASCI and AAP New Member International Ballroom Presentations

2:00 pm - 2:15 pm AAP New Member Presentation International Ballroom

2:15 pm - 2:30 pm ASCI New Member Presentation International Ballroom

2:30 pm - 2:45 pm AAP New Member Presentation International Ballroom

2:45 pm - 3:00 pm ASCI New Member Presentation International Ballroom

3:00 pm - 3:30 pm Break

3:30 pm - 4:00 pm Targeting the PI3K/AKT/mTOR International Ballroom pathway in breast cancer José Baselga, MD, PhD, Memorial Sloan-Kettering Cancer Center

4:00 pm - 4:30 pm Engineering T cells for cancer: CARs International Ballroom and beyond Carl June, MD, University of Pennsylvania School of Medicine

4:30 pm - 4:45 pm JCI Editor Update International Ballroom

4:45 pm - 5:15 pm ASCI Presidential Address Peter Tontonoz, MD, PhD, University of California, Los Angeles International Ballroom

5:15 pm - 5:45 pm ASCI/Stanley J. Korsmeyer Award Lecture Beth Levine, MD, UT Southwestern Medical Center International Ballroom

5:45 p.m - 6:15 p.m APSA - Lasker Foundation Award Lecture Napoleone Ferrara, MD, University of California, San Diego International Ballroom

6:00 pm - 9:30 pm Poster Viewing Imperial Ballroom 7:00 pm - 9:00 pm AAP Offsite President’s Dinner

Saturday, April 26th

Time Event Location

7:00 am - 8:00 am Mentoring Breakfast Moulin Rouge

7:00 am - 8:00 am AAP Council Meeting

8:15 am – 5:15 pm Plenary Session II: Understanding Disease Mechanisms to Improve Human Health International Ballroom

8:00 am – 8:45 am Gene therapy for Leber’s International Ballroom Congenital Amaurosis as a stepping stone for treating other binding diseases Jean Bennett, MD, University of Pennsylvania School of Medicine

8:45 am – 9:15 am Perturbing the early life International Ballroom Microbiome and its consequences Martin Blaser, MD, New York University School of Medicine

7:00 pm - 9:00 ASCI Dinner and New Member Induction Ceremony How to Solve a Scientific Puzzle: Clues from Stockholm and Broadway, Speaker: Joseph L. Goldstein, MD, UT Southwestern Medical Center Moulin Rouge

7:00 pm - 9:00 pm APSA Dinner Outing Groups will meet by the Registration Desk at the Fairmont Hotel (Local Restaurants)

9:00 pm - 12:00 am APSA Welcome Reception John Hancock Center APSA Presidential Address Evan Noch, MD, PhD, APSA President John Hancock Center Suggested Attire: Business Casual Shuttles will be running from the Fairmont B2 motor lobby to the Hancock Center (and returning to the Fairmont) continuously from 8:30pm Friday wth the last Shuttle leaving Hancock at 12:30 am Saturday.

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

1:30 pm – 2:00 pm APSA Keynote Speaker Opening Doors Worldwide through Medical Science Peter Agre, MD, Johns Hopkins University International Ballroom

2:00 pm - 2:30 pm Regenerative Medicine: New Approaches to Healthcare Anthony Atala, MD, International Ballroom Wake Forest Institute for Regenerative Medicine 2:30 pm - 3:00 pm The Acute Myeloid Leukemia Genome(s) Timothy Ley, MD, International Ballroom Washington University School of Medicine

2:30 pm - 3:30 pm APSA Panels

2:30 pm - 3:30 pm APSA Panel: Global Health Crystal Room Panelists: Shannon Galvin, MD; Robert L. Murphy, MD; Olufunmilayo Olopade, MD, FACP Moderator: Jaimo Ahn, MD, PhD

2:30 pm - 3:30 pm APSA Panels: Public Outreach of Gold Room the Physician-Scientist Panelists: Bechara Choucair, MD; Niranjan Karnik, MD, PhD; Claire Pomeroy, MD, MBA; Ralph Horwitz, MD Moderator:Shwayta Kukreti, MD, PhD

3:00 pm - 3:30 pm Break

3:30 pm – 3:40 pm Best Poster Awards International Ballroom

3:40 pm - 4:00 pm AAP Business Meeting International Ballroom

4:00 pm - 4:30 pm AAP Presidential Address International Ballroom J. Larry Jameson, MD, PhD, University of Pennsylvania School of Medicine 4:30 pm - 5:15 pm Kober Medal Presentation Recipient: Elizabeth G. Nabel, MD, Brigham and Women’s Hospital, Harvard Medical School

9:15 am – 9:30 am APSA trainee oral abstract presentation International Ballroom Ryanodine-Receptor Mediated Calcium Leak Drives Progression of Atrial Fibrillation David Y. Chiang Baylor College of Medicine

9:30 am - 10:00 am Strategies to fix a broken heart Christine E. Seidman, MD, Brigham and Women’s Hospital, Harvard Medical School International Ballroom

10:00 am - 10:30 am Break 10:30 am – 11:00 am Inaugural ASCI/Harrington Prize Lecture Found in Translation: New Insights into the Pathogenesis and Treatment of Marfan Syndrome and Related Disorders Harry Dietz, MD, Johns Hopkins University International Ballroom 11:00 am - 11:15 am APSA trainee oral abstract presentation International Ballroom A conditional NF2 mouse model of schwannomagenesis that recapitulates human disease JR Gehlhausen Indiana University School of Medicine

11:15 am - 11:45 am APSA Keynote Speaker International Ballroom HIV and the kidney: From mice to men Mary Klotman, MD, Duke University (Sponsored by IDSA)

11:45 am - 1:30 pm Poster Session with Lunch Imperial Ballroom

12:45 pm – 1:30 pm Poster Reviewer Meeting Imperial Ballroom

1:30 pm – 2:00 pm Poster Dismantle Imperial Ballroom

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Presenter: Eugene Braunwald, MD, Brigham and Women’s Hospital, Harvard Medical School

International Ballroom7:30 pm - 9:00 pm APSA Dinner & Speaker

The Rotavirus Vaccine: From Bench To BedsidePaul Offit MD, Children’s Hospital of Philadelphia Moulin Rouge

7:00 pm - 10:00 pm AAP Reception and Dinner Imperial Ballroom

9:00 pm - 10:00 pm AAP Dinner Speaker Imperial BallroomEnding the HIV/AIDS Pandemic: Science and PolicyAnthony S. Fauci, MD,National Institute of Allergy and Infectious DiseaesAPSA members join AAP members in the Imperial Ballroom

10:00 pm - 12:00 am Dessert Reception (open to all attendees) Imperial Ballroom Foyer

Sunday, April 27thTime Event Location

8:00 am - 9:30 am Interest Groups and Mentorships Moulin Rouge

9:30 am - 10:00 am APSA Keynote Gold RoomFrom Diagnostics to Theranostics: Expanding Horizons for Clinician-Scientists in ImagingHedvig Hricak, MD, PhD, Memorial Sloan-Kettering Cancer Center (Sponsored by RSNA)

10:00 am - 11:00 am Panel - Post-Graduate Opportunities Gold RoomPanelists: Holly J. Humphrey, MD, MACP;William N. Kelley, MD;Moderator: David M. Markovitz, MD

10:00 am - 11:00 am Panel - Social Sciences and Humanities Crystal RoomDavid Chan, MD, PhD; Joel Howell, MD, PhD;Bapu Jena, MD, PhD

11:00 am - 12:00 pm Panel - Policy Gold RoomPanelists: Martin Burke, DO; Larissa Lapteva, MD, MHS; Lex Van DerPloeg, PhDModerator: Jennifer M. Kwan, MD, PhD

11:00 am - 12:00 pm Panel - MSTP Admissions panel for Crystal Roomundergraduates Panelists: Hossein Ardehall, MD, PhD;Lawrence (Skip) Brass, MD, PhD; Marcus Clark, MDAnisley Valenciaga

12:30 pm - 2:00 pm Residency Luncheon Moulin Rouge

Participating Institutions:Brigham and Women’s Hospital - Internal MedicineCase Western Reserve - Internal Medicine Physician-Scientist TrackChildren’s Hospital Los Angeles (University of Southern California) George

Donnell Society for Pediatric ScientistsCincinnati Children’s Hospital - PediatricsNationwide Children’s Hospital - Pediatric Integrated Research PathwayThe Ohio State University Physician Scientist Training ProgramUniversity of California, Los Angeles - RadiologyUniversity of Iowa Carver College of Medicine - Physician-Scientist Training

PathwayUniversity of Minnesota - Physician-Scientist Training ProgramUniversity of Rochester Pediatric Residency Program, Research TrackUniversity of Chicago Northside Department of Pathology

Residency ProgramVanderbilt University School of Medicine - Physician-Scientist Training

ProgramWeill Cornell Medical College - Internal Medicine Physician-Scientist Track

2:30 pm - 3:30 pm Executive Council/Board of State RoomDirectors Transition MeetingAll incoming and outgoing EC and BoD members must attend.

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Mark Courtney is an Associate Professor in Emergency Medicine at Northwestern University. He received his MD from Baylor College of Medicine in 1997 and completed his residency at the Carolinas Medical Center. His research focuses on the optimal acute diagnosis and therapy of venous thromboembolic disease. He is also interested in bioinformatics; blood/bleeding Disorders (anemia, clotting, etc.); cardiovascular diseases; pulmo-nary thromboembolism and resuscitation.

Mark Courtney, MDKeynote Speaker

Friday 11-11:45 amInternational Ballroom

Brian Kobilka, MDKeynote Speaker

Friday 12-12:45 pmInternational Ballroom

Brian Kobilka is the Helene Irwin Fagan Chair in Cardiology and Professor of Medicine (Cardiovascular) at Stanford University School of Medicine. He is also the co-founder of ConfometRx, a biotechnology compa-ny focusing on G protein-coupled receptors. The goal of research in his lab is to characterize the structure and mechanism of activation of G protein coupled receptors (GPCRs). His lab has employed a variety of approaches including cell biology, gene disruption in mice, and in vivo physiology to determine the role of specific adren-ergic receptor subtypes in normal physiology. In 2007 he obtained two crystal structures of the beta2 adren-ergic receptor (beta2AR): as a b2AR-Fab complex and as a beta2AR-T4L fusion protein. These were the first structures of a hormone/neurotransmitter activated GPCR. The method that he developed to obtain crystals of the beta2AR (generating T4 lysozyme fusion proteins) has subsequently been used to crystallize twelve other GPCRs including the following structures from our lab: the M2 and M3 muscarinic receptors, the mu- and del-ta-opioid receptors, and the protease activated receptor (PAR1). These structures all represent inactive states of these GPCRs. More recently, his group has succeeded in obtaining active state structures of the b2AR including the b2AR-Gs complex. These crystallography studies provide high-resolution snap-shots of transmembrane sig-naling by G protein coupled receptors, as well as insights into the structural basis for ligand binding specificity.Dr. Kobilka won the Nobel Prize in Chemistry in 2012 for his work on GPCRs and he was named a member of the National Academy of Sciences in 2011.

Napoleone Ferrara received his M.D. from the University of Catania Medical School, Catania, Italy. He is the Senior Deputy Director for Basic Sciences at the University of California, San Diego Moores Cancer Center, where he is also a Distinguished Professor of Pathology.

fsdThe main research theme of his lab is the regulation of angiogenesis. In 1989 they reported the isolation and cDNA cloning of vascular endothelial growth factor (VEGF). He then demonstrated that VEGF is a key regu-lator of angiogenesis in a variety of physiological processes including embryonic development, reproductive functions and skeletal growth. In addition, he discovered that VEGF is a major mediator of tumor angiogenesis. These studies led to the development of a humanized anti-VEGF antibody, bevacizumab (Avastin®), which was initially approved by the FDA in 2004 for the treatment, in combination with 5-FU-based chemotherapy, of first-line metastatic colorectal cancer. Bevacizumab was then approved in 2006 for the treatment of second-line metastatic colorectal cancer. In 2006, bevacizumab was also approved in combination with carboplatin and paclitaxel for the first-line treatment of patients with recurrent or metastatic non-squamous non-small cell lung cancer. Bevacizumab has been subsequently approved also for the treatment of renal cell carcinoma.

His lab’s studies on the role of VEGF in intraocular neovascularization also led to the clinical development of an anti-VEGF antibody fragment, ranibizumab (Lucentis®), as a potential therapy for wet (neovascular) age-related macular degeneration (AMD), the leading cause of blindness for people over the age of 55. In 2006, ranibizumab was approved for the treatment of wet AMD after multiple Phase III trials demonstrating that ad-ministration of such agent results in substantial visual acuity gains. Since 2006, the FDA has expanded the use of ranibizumab, approving it to treat retinal vein occlusion in 2010 and diabetic macular edema in 2012.

His lab is presently focusing on investigating mechanisms of tumor angiogenesis alternative to VEGF, in partic-ular the role of factors produced by myeloid cells and fibroblasts in refractoriness/resistance to VEGF inhibitors.

Napoleone Ferrara, MDKeynote Speaker

Lasker Foundation Award WinnerFriday 5:45-6:15 pm

International Ballroom

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A native Minnesotan, Peter Agre studied chemistry at Augsburg College (B.A. 1970). While working on cholera as a medical student at Johns Hopkins (M.D. 1974), Agre developed a love for biomedical research. Following an Internal Medicine Residency at Case Western Reserve University Hospitals of Cleveland and a Hematology-Oncology Fellowship at the University of North Carolina at Chapel Hill, Agre returned to Johns Hopkins as a Postdoctoral Fellow in the Department of Cell Biology in the laboratory of his medical school room-mate, Vann Bennett, where he began studies of membranes of red blood cells from patients with congeni-tal anemias.

Recruited by Victor McKusick, Agre joined the faculty at the Johns Hopkins School of Medicine in 1984 and rose to Professor of Biological Chemistry and Professor of Medicine. Following a term as Vice Chancellor for Science and Technology at Duke Medical Center, Agre returned to Johns Hopkins in January 2008, where he is University Professor, Gilman Scholar, and Director of the Malaria Research Institute at the Bloomberg School of Public Health.

In 1992, the Agre lab became widely recognized for discovering the aquaporins, a family of water channel proteins found throughout nature and responsible for numerous physiological processes in humans—including kidney concentration, as well as secretion of spinal fluid, aqueous humor, tears, sweat, and release of glycerol from fat. Aquaporins have been implicated in multiple clinical disorders—including fluid retention, bedwetting, brain edema, cataracts, and arsenic poisoning. Water transport in diverse organisms, including Anopheles mosquitoes and malaria parasites, involve aquaporins.

In 2003, Agre shared the Nobel Prize in Chemistry with Roderick MacKinnon “for discoveries concerning channels in cell membranes.” Agre has received additional honors including 16 honorary doctorates, Commandership in the Royal Norwegian Order of Merit from King Harald V, and the Distinguished Eagle Scout Award from the Boy Scouts of America. Agre is a member of the National Academy of Sciences and the Institute of Medicine. From 2009-10, Agre served as President of the American Association for the Advancement of Sciences.

Peter Agre, MDKeynote Speaker Saturday 1:30 pm

International Ballroom

Mary Klotman, MD Keynote Speaker

Saturday 11:15 amInternational Ballroom

Mary E. Klotman, MD, is R. J. Reynolds Professor and chair of the Department of Medicine at Duke Univer-sity School of Medicine. She earned her undergraduate (zoology) and medical degrees from Duke, and then completed her internal medicine residency and a fellowship in Infectious Diseases in the Department of Med-icine at Duke. She subsequently moved to the National Institutes of Health, where she was a member of the Public Health Service and trained and worked in the Laboratory of Tumor Cell Biology under the direction of Robert C. Gallo, MD.

Klotman joined the faculty at Mount Sinai School of Medicine in New York City, where she was a tenured pro-fessor of medicine and microbiology and held the Irene and Dr. Arthur M. Fishberg Chair in Infectious Diseas-es and oversaw a translational research program in HIV pathogenesis. She also served as chief of the Division of Infectious Diseases for 13 years and co-director of Mount Sinai’s Global Health and Emerging Pathogens Institute. She returned to Duke in March 2010 to become chair of the Department of Medicine.

Klotman’s research interests are focused on the molecular pathogenesis of Human Immunodeficiency Virus 1 (HIV-1) infection. Among many important contributions to this field, Klotman and her collaborators demon-strated that HIV resides in and evolves separately in kidney cells and infects these cells via direct contact with infected T-cells, critical steps in HIV-associated kidney disease. Her research group also has determined the role of soluble host factors involved in an innate immune response to HIV, including antimicrobial peptides that could be involved in sexual transmission of HIV. She has mentored a number of pre- and post-doctoral students in laboratory-based research in infectious diseases.

Dr. Klotman is a member of and on the Council of AAP and currently serves as an associate editor of JCI and Annual Reviews of Medicine.

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Paul Offit, MD Keynote Speaker

Saturday, 7:30-9:00 pmMoulin Rouge

Paul A. Offit, MD is the Chief of the Division of Infectious Diseases and the Director of the Vaccine Education Center at the Children’s Hospital of Philadelphia. In addition, Dr. Offit is the Maurice R. Hilleman Professor of Vaccinology and a Professor of Pediatrics at the University of Pennsylvania School of Medicine. He is a recipient of many awards including the J. Edmund Bradley Prize for Excellence in Pediatrics from the University of Maryland Medical School, the Young Investigator Award in Vaccine Development from the Infectious Disease Society of America, and a Research Career Development Award from the National Institutes of Health. Dr. Offit has published more than 150 papers in medical and scientific journals in the areas of rotavirus-specific immune responses and vaccine safety. He is also the co-inventor of the rotavirus vaccine, RotaTeq, recommended for universal use in infants by the CDC; for this achievement Dr. Offit received the Luigi Mastroianni and William Osler Awards from the University of Pennsylvania School of Medicine, the Charles Mérieux Award from the National Foundation for Infectious Diseases; and was honored by Bill and Melinda Gates during the launch of their Foundation’s Living Proof Project for global health. In 2009, Dr. Offit received the President’s Certificate for Outstanding Service from the American Academy of Pediatrics. In 2011, Dr. Offit received the Humanitarian of the Year Award from the Biologics Industry Organization (BIO), the David E. Rogers Award from the American Association of Medical Colleges, the Odyssey Award from the Center for Medicine in the Public Interest, and was elected to the Institute of Medicine of the National Academy of Sciences. In 2012, Dr. Offit received the Distinguished Medical Achievement Award from the College of Physicians of Philadelphia and the Drexel Medicine Prize in Translational Medicine fro the Drexel University College of Medicine. In 2013, Dr. Offit received the Maxwell Finland award for Outstanding Scientific Achievement from the National Foundation for Infectious Diseases, the Distinguished Alumnus award from the University of Maryland School of Medicine, and the Innovators in Health Award from the Group Health Foundation. Dr Offit was a member of the Advisory Committee on Immunization Practices to the Centers for Disease Control and Prevention and is a founding advisory board member of the Autism Science Foundation and the Foundation for Vaccine Research. He is also the author of six medical narratives: The Cutter Incident: How America’s First Polio Vaccine Led to Today’s Growing Vaccine Crisis (Yale University Press, 2005), Vaccinated: One Man’s Quest to Defeat the World’s Deadliest Diseases (HarperCollins, 2007), for which he won an award from the American Medical Writers Association, Autism’s False Prophets: Bad Science, Risky Medicine, and the Search for a Cure (Columbia University Press, 2008), Deadly Choices: How the Anti-Vaccine Movement Threatens Us All (Basic Books, 2011), which was selected by Kirkus Reviews and Booklist as one of the best non-fiction books of the year, Do You Believe in Magic?: The Sense and Nonsense of Alternative Medicine (HarperCollins, 2013), which was selected by National Public Radio as one of the best books of 2013, and Ungodly Acts: The Clash Between Modern Medicine and Religious Belief (Basic Books, 2015).

Hedvig Hricak is Chair of the Department of Radiology, Memorial Sloan-Kettering Cancer Center. She is a member of the Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute and is Professor, Gerstner Sloan-Kettering Graduate School of Biomedical Sciences. Her publications include more than 380 peer-reviewed original research articles and over 135 monographs and book chapters. She has been the editor or coeditor of 18 books and the monographs editor or co-editor of 9 books.

Dr. Hricak has held numerous leadership positions in professional societies and has served as president of the Society for the Advancement of Women’s Imaging (1997-1999), the California Academy of Medicine (1999-2000), the Society of Uroradiology (2001-2003), the New York Roentgen Ray Society (2004-2005), the Radiological Society of North America (2010) and the International Society for Strategic Studies in Radiology (2011-2013).

Dr. Hricak is a member of the Institute of Medicine (IOM) of the National Academy of Sciences (NAS) and a “foreign” member of both the Croatian Academy of Arts and Sciences and the Russian Academy of Medicine. She has served on the Scientific Advisory Board of the National Cancer Institute and the Advisory Council of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) and was a member of the Nuclear and Radiation Studies Board of the NAS. She chaired the NAS Committee on the State of the Science of Nuclear Medicine, which wrote the highly-cited report “Advancing Nuclear Medicine Through Innovation”. She is presently Chair of the IOM Committee on Research Directions in Human Biological Effects of Low-Level Ionizing Radiation.

In recognition of her accomplishments, Dr. Hricak has been elected an honorary fellow or member of 15 international radiological societies and a fellow of the American College of Radiology, the Society of Uroradiology, the International Society for Magnetic Resonance in Medicine, and the American Association for the Advancement of Science (AAAS). She has received numerous awards including the Marie Curie Award of the American Association of Women Radiologists; the gold medals of the International Society for Magnetic Resonance in Medicine, the Association of University Radiologists, the European Society of Radiology and the Asian Oceanian Society of Radiology; the Beclere medal of the International Society of Radiology; the Moroccan Merit Medal; and the Jean A. Vezina French Canadian Award of Innovation. She also received the Order of the Croatian Morning Star of Katarina Zrinska, a presidential award of Croatia. She holds an honorary doctorate in medicine from the Ludwig Maximilian University in Munich.

Hedvig Hricak, MD, PhD Keynote Speaker

Sunday, 9:30-10 am Gold Room

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After her residency training in emergency medicine in 2002, Dr. Amy Kaji performed a disaster medicine re-search fellowship at Harbor-UCLA, during which time she achieved her MPH and PhD in epidemiology from the UCLA School of Public Health in 2007. Her dissertation described the lack of hospital disaster preparedness in Los Angeles County. Currently, Dr. Kaji serves on the American College of Emergency Physicians (ACEP) Disaster Committee as well as the Society for Academic Emergency Medicine (SAEM) Disaster Medicine Interest Group and Research Committee. Last year, she led the ACEP Disaster committee’s taskforce to develop a research agenda. Dr. Kaji has also served on several Health Resources and Services Administration (HRSA) Grant Review Committees and was a National Research Council’s Report Review Committee member for the 2012 Institute of Medicine’s Report, “Crisis Standards of Care, A Systems Framework for Catastrophic Disaster Response.” In 2013, Dr. Kaji completed a multi-center study to develop a decision rule for which infants who present with an apparent life threatening event (ALTE) warrant admission to the hospital. In addition to research in out-of-hospital cardiac arrest and emergency medical services, her current research involves serving as a statistical consultant for numerous surgically-related projects, including necrotizing fasciitis, traumatic brain in-jury, in addition to serving as a consultant for the California Pediatric Readiness project in which 300 hospitals were surveyed regarding their supplies, plans, and resources for pediatric disasters and emergencies.

Amy Kaji, MD, PhD, MPHWomen in Medicine Panel

Friday, 2-3pmCrystal Room

Dr. Usha Raj is the Anjuli S. Nayak Professor of Pediatrics, Head of the Department of Pediatrics, and the Physician-in-Chief of the Children’s Hospital of the University of Illinois. Dr. Raj is an internationally renowned neonatologist and physician-scientist, with a strong research program in pulmonary vascular biology. She has been an active member of the American Academy of Pediatrics for over 30 years, an elected member of the American Society for Clinical Investigation for over 20 years, and a member of the Executive Council of the American Physiological Society. Recently, she has recruited numerous new faculty members to spark the growth of various programs in her department. In addition to her administrative, clinical, and research responsibilities, she continues to help guide future physician-scientists along the academic research track.

Usha Raj, MDWomen in Medicine Panel

Friday, 2-3pmCrystal Room

Amy Chen, MD, MPHWomen in Medicine Panel

Friday, 2-3pmCrystal Room

Amy Chen, MD, MPH, FACS, is the William and Lillian Hackerman Professor in the Department of Otolaryn-gology and Head and Neck Surgery at The Emory University School of Medicine. Her expertise is in thyroid and upper aerodigestive tract malginancies. She has a joint appointment at Winship Cancer Institute and at Emory’s Rollins School of Public Health She has also served as Director of Health Services Research in the Department of Surveillance and Health Policy Research of the American Cancer Society.

Dr. Chen has been instrumental in developing a team approach to patient care. She developed and led the multidisciplinary thyroid and head and neck tumor conference. Her primary focus of research is in measuring outcomes of oncology treatment as well as measuring determinants of successful outcomes of care. Dr. Chen’s research agenda is to create a multi-disciplinary, multi-site center dedicated to health services research, out-comes, and quality of care. Her secondary focus of research is directed toward translational research of upper aerodigestive tract malignancies.

Dr. Chen joined the Emory faculty in 2001 after a fellowship in Head and Neck Oncologic Surgery at the MD Anderson Cancer Center in Houston. Prior to that fellowship she was a resident in Otolaryngology and General Surgery at Baylor College of Medicine, also in Houston.

She is board certified by the American Board of Otolaryngology and holds a Master of Public Health degree from the University of Texas School of Public Health. Dr. Chen has received numerous awards and honors, among them the Percy Memorial Research Award, the Rande Lazar Health Services Research Award, the Amer-ican Head and Neck Society Scholarship Award, and The Women’s Fund for Health, Education and Research Grant. She is married and has two teenage daughters.

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Shannon Galvin, MDGlobal Health Panel

Saturday, 2:30-3:30pmCrystal Room

Dr. Shannon Galvin is the Director of Clinical Programs & Training for the Center for Global Health. She coordinates and participates in clinical and research activities initiated and supported by the Center, aiming to facilitate new research projects of global import by Northwestern and partner researchers. This includes supporting existing research projects in HIV care and ART treatment, rapid diagnostics and models of clinical care in resource limited settings. In addition, Dr. Galvin assists in identifying global health opportunities both for new researchers and established researchers whose work translates to international settings. Dr. Galvin also serves as clinical advisor for any clinical activities of the Center.

Dr. Galvin has spent ten years as an infectious disease physician and HIV researcher in resource limited settings. Prior to joining Northwestern she was an Assistant Professor in Infectious Diseases at University of North Carolina at Chapel Hill. There she spent time living and working on the UNC Project Malawi in Lilongwe, Malawi. She also served as HIV clinical advisor to IntraHealth International and worked on HIV treatment programs in Rwanda, Ethiopia, Southern Sudan and Namibia as well as STD projects in India and Armenia and the global Capacity Project. Her research interests include correlates of immunity to HIV, diagnosis of acute HIV and delivery of care in resource limited settings. She has been principal investigator on clinical studies in Malawi and Swaziland and understands the tasks required to ethically and effectively perform research in sub-Saharan Africa as well as the challenges and rewards of providing care to communities with high burden of disease.

Robert Murphy, MDGlobal Health PanelFriday, 2:30-3:30pm

Crystal Room

Dr. Robert L. Murphy received his AB from Boston University, an MD from Loyola University and later completed his postgraduate training in Internal Medicine and Infectious Diseases at Northwestern University. Dr. Murphy is currently the John P. Phair Professor of Infectious Diseases and Professor of Medicine and Biomedical Engineering at Northwestern University where he is Director, Center for Global Health. He holds an academic appointment as Visiting Professor of Immunology and Infectious Diseases at Harvard School of Public Health. Dr. Murphy’s primary research interest is in the scale up of therapy for HIV/AIDS, tuberculosis and malaria in sub-Saharan Africa. Dr. Murphy was the founding Country Director of the Harvard President’s Emergency Program for AIDS Relief (PEPFAR) in Nigeria, an effort that resulted in the establishment of 53 HIV/AIDS treatment centers that cared for over 150,000 persons with HIV infection. He is Principal Investigator for two of Northwestern’s Fogarty/NIH International Research Training grants based in Nigeria and Mali and is a co-investigator on the Medical Education Partnership Initiative Nigeria based at the University of Ibadan. As part of the Fogarty Frameworks program, he leads the effort to establish Biomedical Engineering programs at the Universities of Ibadan and Lagos in Nigeria. In Mali, he is the NIH extramural Program Director for tuberculosis and retrovirology at the University of Bamako.

Dr. Olopade, a board certified internist and medical oncologist, Walter L. Palmer Distinguished Service Professor of Medicine and Human Genetics, Associate Dean of Global Health and Director, Center for Clinical Cancer Genetics at The University of Chicago.

A global leader in cancer genetics, Dr. Olopade seeks to identify those at risk for hereditary breast and ovarian cancer earlier in life, intervene aggressively to reduce risk and preempt disease development to effectively control cancer. She studies familial forms of cancers, molecular mechanisms of tumor progression in high-risk individuals as well as genetic and non-genetic factors contributing to tumor progression in diverse populations. Her current laboratory research is fo-cused on using whole genome technologies and bioinformatics to develop innovative approaches to accelerate progress in cancer research and reduce disparities in health outcomes.

Dr. Olopade is an elected member of the American Society for Clinical Investigation, the Association of American Physi-cians, Institute of Medicine of the National Academies, American Academy of Arts and Sciences and the American Philo-sophical Society. A recipient of numerous honors, including honorary degrees from Bowdoin and Princeton Universities, Doris Duke Distinguished Clinical Scientist and Exceptional Mentor Award, American Cancer Society Clinical Research Professorship, MacArthur Foundation “Genius” Fellowship and Officer of the Order of Nigeria Award. Dr. Olopade cur-rently serves on the Board of Directors for the American Board of Internal Medicine, the National Cancer Advisory Board, Susan G. Komen for the Cure and the Lyric Opera Board.

Olufunmilayo Olopade, MDGlobal Health PanelFriday, 2:30-3:30pm

Crystal Room

Dr. Karnik is an associate professor of Psychiatry in the Division of Child and Adolescent Psychiatry and Department of Psychiatry at Rush Medical College and an adjunct faculty member in the Department of Community, Systems and Mental Health Nursing at the College of Nursing, Rush University. His research focuses on community-based interventions for high-risk youth with psyciatric and substance use disorders. In the past, he has worked with refugee children on the Pakistan-Afghan border, street children in India, foster youth in central Illinois, and incarcerated youth in California. More recently, he has worked at a youth homeless shelter in San Francisco and is continuing this work with homeless youth in Chicago. The major focus of his research is using mobile health technologies to bridge the needs of vulnerable youth and enable providers to better deliver services to at-risk populations. He serves on the Board of Directors of the not-for-profit Generations of Hope Development Corporation in Champaign, Illinois that seeks to build intergenerational communities as intervention for a variety of vulnerable populations.

Niranjan Karnik, MD, PhDPublic Outreach PanelFriday, 2:30-3:30pm

Gold Room

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Bechara Choucair, M.D. serves as Commissioner of the Chicago Department of Public Health. Appointed on November 25, 2009, Dr. Choucair is re-shaping the department to meet the public health challenges of the 21st century. Most recently, with the full support of Mayor Rahm Emanuel, Dr. Choucair unveiled “Healthy Chicago,” the first city-wide comprehensive public health agenda. Healthy Chicago is a call to action for all Chicagoans to work together on a common vision of making Chicago the healthiest city in the nation. Under Dr. Choucair’s leadership, the Chicago Department of Public Health became the first big city public health agency to receive national accreditation. Born in Beirut, Lebanon, Dr. Choucair earned a Bachelor of Sciences degree in Chemistry (with distinction) in 1993 and a Medical Diploma in 1997 from the American University of Beirut. From 1997-2000 he completed his Family Medicine Residency at the Baylor College of Medicine in Houston, Texas. In 2009 he earned a Master’s Degree in Health Care Management from the University of Texas at Dallas. From 2001-05, Dr. Choucair served as Medical Director of Crusader Community Health in Rockford, Illinois. From 2005-09, he was Executive Director of Heartland International Health Center. He holds an Adjunct Associate Professor title at the Department of Family & Community Medicine at Feinberg School of Medicine, Northwestern University.

Bechara Choucair, MDPublic Outreach PanelFriday, 2:30-3:30pm

Gold Room

Claire Pomeroy, MD, MBAPublic Outreach PanelFriday, 2:30-3:30pm

Gold Room

Dr. Holly J. Humphrey is the Ralph W. Gerard Professor of Medicine and Dean for Medical Education at the University of Chicago. In this role, she oversees medical education for students in the Pritzker School of Medicine and for residents and fellows in graduate medical education programs at the University of Chicago Medical Center. During her career at the university, Dr. Humphrey has launched numerous programs, including the Roadmap to Professionalism initiative to support and enhance the highest professional standards and a curriculum reform effort entitled The Pritzker Initiative: A Curriculum for the 21st Century. Dr. Humphrey is a nationally recognized leader in medical education scholarship with a specific focus on the role of mentoring in medical education. She is the editor of Mentoring in Academic Medicine (2010), published as a part of the American College of Physicians series on Teaching Internal Medicine, and has authored numerous publications on issues related to medical education. Dr. Humphrey’s innovation and leadership are recognized nationally and have led most recently to appointments to the Board of Trustees of the American Board of Internal Medicine Foundation. In 2009, Crain’s Chicago Business featured her as one of their “Women to Watch” and in 2010, the YWCA of Metropolitan Chicago honored her with their Outstanding Leader Award in the Professions.

Holly Humphrey, MDPost-grad Opportunities Panel

Sunday, 10-11 amGold Room

Claire Pomeroy is president of the Albert and Mary Lasker Foundation. She serves as chief executive officer of the Foundation and is responsible for overseeing the implementation of programs which advance the Foundation’s mission to “foster the prevention and treatment of disease and disability by honoring excellence in basic and clinical science, and through public education and research advocacy.”

An expert in infectious diseases, Dr. Pomeroy is a long-time advocate for patients, especially those with HIV/AIDS, and public health. She passionately supports ongoing investment in the full range of research. She continues to lead an active research team studying host responses to viral infections. She has a special interest in health care policy, with a focus on the importance of the social determinants of health. She has published more than 100 articles and book chapters and edited three books.

Dr. Pomeroy is a member of the Board of Trustees for the Morehouse School of Medicine and serves on the Board of Directors for the Sierra Health Foundation, the Foundation for Biomedical Research, and PRIDE Industries. She is co-chair of the Blue Ridge Academic Health group and serves on the VA National Academic Affiliations Council. Past roles include chair of the Board of Directors for the Association of Academic Health Centers (AAHC) and chair of the Council of Deans and Board member of the Association of American Medical Colleges (AAMC). She was elected in 2011 as member-at-large representative for the AAAS medical sciences section. Dr. Pomeroy was inducted into the Institute of Medicine in 2011.

Dr. Pomeroy received her bachelors and medical degrees from the University of Michigan and completed her residency and fellowship training in internal medicine and infectious diseases at the University of Minnesota. She earned an MBA from the University of Kentucky. She has held faculty positions at the University of Minnesota, University of Kentucky and University of California (UC) Davis; she is currently professor emerita at UC Davis. Dr. Pomeroy was chief of infectious diseases and associate dean for research and informatics at the University of Kentucky. She joined UC Davis in 2003 as executive associate dean and in 2005 was appoint-ed CEO and vice chancellor of the Health System and dean of the School of Medicine. She became president of the Albert and Mary Lasker Foundation in June, 2013.

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David Chan, MD, PhDSocial Sciences Panel

Sunday 10-11 amCrystal Room

David Chan, MD, PhD, is an Assistant Professor of Medicine at the Stanford School of Medicine, a Core Faculty Member at the Center for Health Policy / Primary Care and Outcomes Research, an investigator at the Center for Health Care Evaluation at the Department of Veterans Affairs, and a research fellow at Partners Health Care.Chan’s research focuses on the micro-foundations of variation in productivity within US health care. In particular, he is interested in studying what drives more or less efficient physician behavior, including organizational features of workplace design, financial and social incentives, and the use of information. Another vein of research investigates the response of health care firms to policy measures intended to improve health care delivery, such as quality or throughput.He received BA degrees in mathematics and economics from the University of California, Riverside, master’s degrees in policy and economics from the London School of Economics and Oxford University, where he studied as a Marshall Scholar, a medical degree from UCLA, and a PhD in economics at MIT. He trained in internal medicine at Brigham and Women’s Hospital and was an instructor of medicine at Harvard Medical School, prior to coming to Palo Alto. He currently is a hospitalist at the Department of Veterans Affairs, Palo Alto.

Joel Howell, MD, PhDSocial Sciences Panel

Sunday 10-11 amCrystal Room

Joel D. Howell, MD, PhD, is the Victor Vaughan Professor of the History of Medicine at the University of Michigan, where he is also a professor in the Departments of Internal Medicine (Medical School), History (College of Literature, Science, and the Arts), and Health Services Management and Policy (School of Public Health). He received his MD and completed his residency in internal medicine at the University of Chicago. He received a PhD in the History and Sociology of Science from the University of Pennsylvania, where he was a Robert Wood Johnson Clinical Scholar. From 1993 to 2007 he directed the Robert Wood Johnson Clinical Scholars Program at the University of Michigan. Howell’s historical work focuses on medical technology, examining how social and contextual factors have shaped its diffusion and clinical application. He attempts to understand why American medicine has become so obsessed with science and technology, and tries to understand policies that have both contributed to and slowed the diffusion of medical technology. He is writing on the history of human experimentation and on ideas about heart attacks. As Director of The Medical

Arts Program at the University of Michigan, he is studying the effects of the arts on clinical practice with a grant from the Doris Duke Charitable Foundation. Howell’s publications have appeared widely in the

medical and the historical literature. His research has been supported both by federal grants and by foundations (he received a Robert Wood Johnson Foundation Investigator Award in Health Policy Research and a Burroughs Welcome Foundation Award in the History of Medicine). In 2013 he received the Nicholas E. Davies Memorial Scholar Award for Scholarly Activities in the Humanities and History of Medicine from the American College of Physicians. In addition to his medical publications, Howell is the author of “Washtenaw County Bike Rides” (University of Michigan Press). Dr. Howell is a practicing internist and attending physician in both the outpa-tient and inpatient settings and regularly teaches in the Medical School, the College of Literature, Science and the Arts, and the Law School.

Bapu Jena, MD, PhDSocial Sciences Panel

Sunday 10-11 amCrystal Room

Anupam B. Jena is an Assistant Professor of Health Care Policy and Medicine at Harvard Medical School and an attending physician in the Department of Medicine at Massachusetts General Hospital, where he practices general inpatient medicine and teaches medical residents. He is also a Faculty Research Fellow at the National Bureau of Economic Research. As an economist and a physician, Dr. Jena’s research involves several areas of health economics and policy including medical malpractice, the economics of medical innovation and cost-effectiveness, the economics of physician behavior, and the effect on physician quality of reforms to medical education. Dr. Jena graduated Phi Beta Kappa from the Massachusetts Institute of Technology with majors in biology and economics. He received his MD and PhD in Economics from the University of Chicago. He completed his residency in internal medicine at Massachusetts General Hospital. In 2007, he was awarded the Eugene Garfield Award by Research America for his work demonstrating the economic value of medical innovation in HIV/AIDS. In 2013, he received the NIH Director’s Early Independence Award to fund research on the physician determinants of health care spending, quality, and patient outcomes.

Dr. Lapteva is a Medical Officer in the Rare Diseases Program in the Office of New Drugs at FDA. She is a clinician and board-certified rheumatologist with experience in clinical research and pharmaceutical product development. Prior to joining the FDA, Dr. Lapteva had served as a lead investigator in clinical studies in rheumatic diseases at the National Institute of Arthritis, Musculoskeletal, and Skin Diseases at the National Institutes of Health. Since joining FDA’s Office of New Drugs, CDER in 2006, Dr. Lapteva has provided regulatory and scientific advice for clinical development programs with novel and repurposed investigational drugs and biological products in various therapeutic areas. She received her medical degree from Moscow Medical Academy, and the degree of Master of Health Sciences from Duke University, North Carolina.

Larissa Lapteva, MD, MHSPolicy Panel

Sunday 11-12 pmGold Room

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Lex H.T. Van der Ploeg is Managing Director for VDP, LLC, an independent consulting agency focused on guid-ing Research and Development for the Biotechnology and Pharmaceutical Industries and private investors. At VDP, LLC, Lex focuses on supporting R&D initiatives from a strategic and tactical perspective, as an integrated member of Management and R&D teams. Lex is CSO for Rhythm pharmaceuticals and functions as Senior Advisor for Strategy and Planning at Somalogic, Inc., he is a member of the board of Directors for Retrotope Inc., and he functions as an advisor to DeuteRx, LLC and is a member of the SAB for Excellentia Global partners.

Lex’s expertise includes development of Diagnostics and Therapeutics including Cancer, Neurodegenerative disorders, Metabolic disorders and Infectious diseases. Prior to starting VDP, LLC Lex was the Sr. Vice President of Integrative Medicine and Translational Science at Abraxis/Celgene. Previously, Dr. Van der Ploeg held the position of, Vice president, Basic Research, and site head at Merck Research Laboratories Boston, focused on oncology and neurodegenerative disease. Prior to starting Merck Research Laboratories Boston in December 2003, Dr. Van der Ploeg held diverse functions at Merck Research Laboratories including site head MRL San Diego and Head Obesity research for Merck Rahway and Banyu, Japan. At Merck, Lex held leadership roles in obesity and metabolism, oncology, neurodegenerative disease research and diagnostics.

Dr. Van der Ploeg received his M.S. degree (Summa Cum Laude) in Biochemistry in 1980 from the University of Amsterdam and his Ph.D. in Biochemistry/Enzymology/Genetics in 1984 from the University of Amsterdam/Netherlands Cancer Research Center. Following receipt of his Ph.D. Dr Van der Ploeg joined the faculty of the Dept of Genetics and Development of Columbia University, as an assistant Professor and received tenure at Columbia University in 1987. Dr Van der Ploeg held an adjunct faculty position at the Dept of Genetics and Development of Columbia University from 1992 through 2009. Dr. Van der Ploeg received numerous awards and grants for his research and has broadly published on his research in peer reviewed journals. He is an inventor on over 50 patents and patent applications.

Dr. Marty Burke earned his undergraduate degree from the University of Notre Dame in History and Pre-professional

Studies in 1985. He then pursued his Doctor of Osteopathy degree at the Chicago College of Osteopathic Medicine (CCOM now known as Midwestern University) graduating in 1989. Upon graduation, he started his Internal

Lex Van Der Ploeg, PhDPolicy Panel

Sunday 11-12 pmGold Room

Martin Burke, DOPolicy Panel

Sunday 11-12 pmGold Room

Ralph Horwitz, MDPost-grad Opportunities Panel

Sunday, 10-11 amGold Room

Dr. Horwitz is Senior Vice President for Clinical Evaluation Sciences and Senior Advisor to the Chairman of Research and Development at GlaxoSmithKline, and Harold H. Hines, Jr. Professor Emeritus of Medicine and Epidemiology at Yale University. Dr. Horwitz trained in internal medicine at institutions (Royal Victoria Hospital of McGill University and the Massachusetts General Hospital) where science and clinical medicine were connected effortlessly. These experiences as a resident unleashed a deep interest in clinical research training which he pursued as a fellow in the Robert Wood Johnson Clinical Scholars Program at Yale under the direction of Alvan R. Feinstein. He joined the Yale faculty in 1978 and remained there for 25 years as Co-Director of the Clinical Scholars Program and later as Chair of the Department of Medicine. Before joining GSK, Dr. Horwitz was Chair of Medicine at Stanford and Dean of Case Western Reserve Medical School. He is an elected member of the Institute of Medicine of the National Academy of Sciences; the American Society for Clinical Investigation; the American Epidemiological Society; and the Association of American Physicians (he was President in 2010). He was a member of the Advisory Committee to the NIH Director (under both Elias Zerhouni and Francis Collins). Dr. Horwitz served on the American Board of Internal Medicine and was Chairman in 2003. He is a Master of the American College of Physicians.

Medicine Residency at CCOM and stayed on there to complete his Fellowship in Cardiovascular diseases by 1995. Having passion for the science of Cardiac Electrophysiology, Dr. Burke joined the University of Chicago for advanced fellowship training in clinical cardiac electrophysiology. In 1996, he joined the faculty at University of Chicago as an Instructor in Medicine. He is currently the Director of the Heart Rhythm Center at the University of Chicago and Professor of Medicine.

His clinical interests remain broad in the field of cardiac electrophysiology including implantation of cardiac rhythm management devices and performing catheter ablation for arrhythmias. Dr. Burke has trained over 100 electrophysiology and general cardiology fellows over the years working across the world today. His research interests have included the management of cardiac device infections and their extraction as well as cardiac arrest and the implantation of new technology cardioverter-defibrillators. Dr. Burke’s ICD research contributed largely to the development of the first entirely subcutaneous cardioverter defibrillator. He has been the principal investigator for several multicenter studies including trials investigating new therapies for electrical heart disease. He has performed many large animal experiments over the years that have investigated new implant-able device technology and the physiology of cardiac arrest.

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Dr. Ardehali received a BS in computer science from the University of Utah. He completed the MSTP at Vanderbilt University, where he earned his PhD in molecular physiology and biophysics. Dr. Ardehali completed both an internal medicine residency and a cardiology fellowship at Johns Hopkins University. Dr. Ardehali has chaired the MSTP Admissions Committee at Northwestern University since 2008. Dr. Ardehali has received numerous awards and is a Fellow of the American Heart Association and the American College of Cardiology. He serves on numerous national committees, including the AHA BCVS leadership committee and is the chair of the AHA Membership/Communications committee. His research involves the role of mitochondria and cellular metabolism in cardiovascular disease which is funded by several awards.

Dr. Brass is a graduate of Harvard College and received his MD/PhD from Case Western Reserve University. From there, he completed his residency training in internal medicine before becoming a fellow in Hematology-Oncology at the University of Pennsylvania. He has been a member of the Penn faculty since 1982, served as Vice Chair for Research in the Department of Medicine, and is currently Professor of Medicine and Pharmacology. In 1998, he became Associate Dean and Director of the MD-PhD program. He is actively working at the national level in the development of training programs for physician-scientists and is a past President of the Association of MD-PhD Program Directors and Administrators and a past Chair of the AAMC GREAT group section on MD-PhD training programs. Dr. Brass’s research interests lie in the fields of hemostasis and vascular biology. He is an elected member of the American Society for Clinical Investigation and Association of American Physicians, an Established Investigator of the American Heart Association, and was a recipient of the IXth Biennial Award for Contributions to Hemostasis Research from the International Society of Thrombosis and Hemostasis.

Dr. Clark received his medical degree from the University of California, Los Angeles and completed his residency at the University of Michigan, Ann Arbor. Dr. Clark joined the University of Chicago in 1993 and is currently Professor of Medicine, Director of the University of Chicago Autoimmunity Center of Excellence, and Chief of the Section of Rheumatology. Dr. Clark was appointed as the Director of the Medical Scientist Training Program in 2011. In addition to seeing patients as a rheumatologist, he has taught extensively in the Immunology graduate program, chaired the Immunology Recruitment and Curriculum Committees, and served on more than 50 thesis committees. Dr. Clark is a nationally recognized authority in B cell biology, having made several substantial contributions to our molecular understanding of how B cells develop in the bone marrow and how they are regulated in the periphery. Also, he has an active research program focused on how B cell activation contributes to the pathogenesis of human lupus nephritis.

Hossein Ardehali, MD, PhDMSTP Admissions Panel

Sunday 11-12 pmCrystal Room

Lawrence (Skip) Brass, MD, PhDMSTP Admissions Panel

Sunday 11-12 pmCrystal Room

Marcus Clark, MDMSTP Admissions Panel

Sunday 11-12 pmCrystal Room

39

José Cavazos, MD, PhDGrant writing panel Thursday 5-6:30 pmImperial Ballroom

Dr. Cavazos received his MD at the Instituto Tecnologico y de Estudios Superiores de Monterrey in Monterrey, Mexico. He did his internship and received his PhD in Neuroscience at University of Wisconsin at Madison. He then did his residency in Neurology at Duke University. Dr. Cavazos is a Professor of Medicine and Neurology and Physiology at the Universit of Texas Health Science Center in San Antonio. He is currently the Assistant Dean for the MD/PhD program as well as the Residency Program Director for Clinical Neurophysiology. He serves in multiple other capacities includeing being the Director of Research at the South Texas Comprehensive Epilepsy Center and the Directorof the San Antonio VA Epilepsy Center of Excellence and the VA Neurodiagnostic Center. His laboratory studies activity-dependent plasticity in the hippocampal formation in the developing, adult, and aged brain using a variety of experimental models of epilepsy, seizures, and epileptogenesis. Previous studies from his laboratory have shown that repeated seizures induce progressive neuronal death and axon sprouting that permanently alter the hippocampal circuitry lending it more susceptible to additional seizures and memory dysfunction. They currently are investigating the molecular mechanisms that link the synchronous neuronal hyperexcitability with these morphological events, including the role of caspases using in-vivo models and in-vitro organotypic hippocampal slice cultures. His lab investigates the features of seizure-induced axon sprouting in other limbic circuitries using anatomical tracing techniques, and their electrophysiological consequences in the neuronal excitability of the abnormally connected circuitry.

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Interest Group MentorsInfectious DiseasesInfectious Diseases Society of America

1. Paul A Offit, MD Chief, Division of Infectious Diseases & Director of the Vaccine Education Center Professor of Vaccinology and PediatricsThe Children’s Hospital of Philadelphia

2. Mary E Klotman, MD Chief, Department of Medicine Professor of Medicine, Pathology, Molecular Genetics and MicrobiologyDuke University Medical Center

3. Barbara Kazmierczak, MD, PhDAssociate Professor of Medicine (Infectious Diseases) & Microbial PathogenesisAssociate Director of the MD/PhD ProgramYale University

PediatricsSociety for Pediatric Research, American Society for Clinical Investigation, Infectious Diseases Society of America

1. Jake Kushner, MD Chief, Pediatric Diabetes and EndocrinologyAssociate Professor of Pediatrics & Molecular and Cellular Biology Baylor University President-elect of Society for Pediatric Research

2. Juliane Bubeck Wardenburg, MD, PhDAssociate Professor, Departments of Pediatrics and MicrobiologyThe University of Chicago

3. Sing Sing Way, MD, PhDPauline and Lawson Reed Chair, Division of Infectious DiseasesAssociate Professor, University of Cincinnati Department of Pediatrics Cincinnati Children’s Hospital Medical Center

Emergency MedicineSociety for Academic Emergency Medicine & American College of Emergency Physicians

1. Amy Kaji, MD, PhDDirector, South Bay Disaster Resource Center Associate Professor of Clinical MedicineHarbor UCLA Medical Center

2. D Mark Courtney, MDAssociate Professor in Emergency MedicineNorthwestern University Feinberg School of Medicine

NeurologyAmerican Neurological Association

1. Puneet Opal, MD, PhDAssociate Professor in Neurology & Cell and Molecular Biology Northwestern University Feinberg School of Medicine

RadiologyRadiological Society of North America

1. Hedvig Hricak, MD, PhDChair, Department of Radiology & Carroll and Milton Petrie ChairMemorial Sloan-Kettering Cancer Center

2. Joy S Sclamberg, MDAssistant Professor of Diagnostic Radiology & Director of the Residency Training ProgramRush University Medical CenterPresident of the Chicago Radiological Society

PathologyAmerican Society for Investigative Pathology & Intersociety Council for Pathology Information

1. Karen Kaul, MD, PhDChair, Department of Pathology and Laboratory AdministrationNorthshore Health Systems

2. Jan Nowak, MD, PhDMedical Director, Molecular Diagnostics & CytogeneticsNorthshore University Health System

3. Christopher Weber, MD, PhDAssistant Professor of PathologyThe University of Chicago

DermatologySociety for Investigative Dermatology and The Edwin Everest Foundation

1. Kathleen Green, PhD Chair of Dermatology; Director, Skin Disease Research Center; Professor in Dermatology and Peds-DermatologyNorthwestern University Feinberg School of Medicine

2. Amy S. Paller, MDAssociate Professor in Medicine-Cardiology, Molecular Pharamcology and Biological ChemistryNorthwestern University Feinberg School of Medicine

3. Narat John Eungdamrong, MD, PhD Dermatology Resident Physician, New York University Sulzberger Research Fellow, Columbia University Medical Center

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CardiologyAmerican Heart Association

1. Hossein Ardehali, MD, PhDAssociate Professor in Medicine-Cardiology, Molecular Pharamacology andBiological ChemistryNorthwestern University Feinberg School of Medicine

2. Jalees Rehman, MDAssociate Professor of Medicine and PharmacologyUniversity of Illinois at Chicago

GastroenterologyAmerican Gastroenterological Association & American Society for Clinical Investigation

1. Vincent Yang, MD, PhDProfessor and Simons Chair of MedicineStony Brook University School of Medicine

2. Eugene B. Chang, MDMartin Boyer Professor of Medicine, Associate Section Chief for ResearchThe University of Chicago

3. John M. Carethers, MD John G. Searle Professor and Chair of the Department of Internal Medicine Universit of MichiganSurgeryAmerican Society for Clinical Investigation

1. Jaimo Ahn, MD, PhDAssistant Professor of Orthopaedic SurgeryUniversity of Pennsylvania

2. Peter J. Gruber, MD, PhDProfessor of Cardiothoracic SurgeryUniversity of Iowa Carver College of Medicine

Hematology/OncologyAmerican Society for Clinical Investigation

1. Everett Vokes, MDChairman, Department of Medicine & Physician in Chief University of Chicago

Internal Medicine/ Research-track Residency1. Brittaney Weber, MD

Resident in MedicineBrigham and Women’s & Massachusetts General

First Name Last Name Email Address Kate Ackerman [email protected] University of Rochester Medical CenterAlexander Adami [email protected] University of Connecticut Health CenterRobert Adams [email protected] Saint Louis UniversityJaimo Ahn [email protected] University of Pennsylvania School of MedicineYohance Allette [email protected] IUSOM-MSTPMeghan Althoff [email protected] Tulane University School of Medicine Emily Anstadt [email protected] University of Connecticut (UCHC)Hossein Ardehali [email protected] Northwestern UniversityRebecca Autenried [email protected] University of IowaRobert Baiocchi [email protected] The Ohio State University College of MedicineFiyinfolu Balogun [email protected] University of ChicagoAbhik Banerjee [email protected] University of Southern CaliforniaFrank Barrows [email protected] Northwestern University Feinberg School of MedicineAdrienne Barry [email protected] University of IllinoisFahmin Basher [email protected] MUSC College of Graduate StudiesRobert Bauer [email protected] University of Illinois - Urbana-Champaign Tim Beck [email protected] Drexel University College of MedicineRussell Becker [email protected] University of Chicago Pritzker School of MedicineBrian Becknell brian.becknell@ Nationwide Children’s Hospital - nationwidechildrens.org Pediatric Integrated Research PathwayJason Beckta [email protected] Virginia Commonwealth University School of MedicineErin Beisner [email protected] University of Illinois - ChicagoJonathan Bell [email protected] Northwestern University Feinberg School of MedicineRaphael Bernard-Valnet [email protected] Association medecine pharmacie sciences Anya Bershad [email protected] University of ChicagoEvan Biggs [email protected] University of Chicago MSTPDavid Blair [email protected] University of ChicagoJennifer Blase [email protected] Saint Louis University School of MedicineMariam Bonyadi [email protected] University of Illinois - Urbana-Champaign Mazdak Bradberry [email protected] University of Wisconsin

10th APSA Annual Meeting Attendees

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Lawrence (Skip) Brass [email protected] University of PennsylvaniaDaniel Brenner [email protected] Washington University - St. LouisStephanie Brosius [email protected] University of Alabama - BirminghamMaher Budron [email protected] Depaul UniversityJason Buhrman [email protected] University of Illinois - ChicagoJeffrey Bunker [email protected] University of Chicago MSTPJames Byrne [email protected] University of North Carolina - Chapel HillJavier Cabrera-Perez [email protected] University of Minnesota Medical School, TCJudd Cahoon [email protected] University of Utah School of Medicine Daniel Camacho [email protected] University of Chicago MSTPSofia Campos [email protected] University of California, San DiegoSophia Canavan [email protected] University of Chicago MSTPAdam Canver [email protected] Drexel University College of MedicinePeter Carlson [email protected] University of Wisconsin School of Medicine and Public HealthEileen Carpenter [email protected] Stony Brook University School of MedicineBenjamin Casterline [email protected] University of Chicago MSTPDavid Chan [email protected] Stanford UniversityHsiang-Chun Chang [email protected] Northwestern University Feinberg School of MedicineMichael Chen [email protected] Loyola UniversityPo-Han Chen [email protected] Northwestern University Feinberg School of MedicineAmy Y. Chen [email protected] Emory University School of MedicineIrene Chernova [email protected] Perelman Sch of MedicineJustin Chew [email protected] University of ChicagoDavid Chiang [email protected] Baylor College of MedicineVida Chitsazzadeh [email protected] University of Texas, HoustonVivian Choi [email protected] University of ChicagoBechara Choucair [email protected] Chicago Public Health DepartmentStephen Chrzanowski [email protected] University of FloridaMarcus Clark [email protected] University of Chicago Pritzker School of MedicineChristopher Cole [email protected] Washington University - St. Louis School of MedicineMark Courtney [email protected] Northwestern University

Andrew Cox [email protected] University of Rochester

Kelly Craven [email protected] IUSOM-MSTPSara Culleton [email protected] IUSOM-MSTPMohammed Dany [email protected] Medical University of South CarolinaRyan Day [email protected] Washington University St. Louis School of MedicineErin DeCloux [email protected] University of Wisconsin School of Medicine & Public HealthDaniel DelloStritto [email protected] Northeast Ohio Medical UniversityDanielle Desjardins [email protected] MUSC College of Graduate StudiesScott Drutman [email protected] Weill-Cornell Medical CollegeLeanne Dumeny [email protected] University of FloridaKimberly Engle [email protected] The Sherwood Group, Inc.Hanna Erickson [email protected] University of Illinois at Urbana-ChampaignBrandon Farmer [email protected] Western Kentucky UniversityLaurence Feldmeyer [email protected] CHUVD. Luke Fischer [email protected] Michigan State UniversityStephen Folmsbee [email protected] Northwestern UniversityDaniel Fox [email protected] University of IowaThushara Galbadage [email protected] Texas A&M Health Science Center College of MedicineShannon Galvin [email protected] Northwestern UniversityYihe Gao [email protected] University of Chicago MSTPJeff Gehlhausen [email protected] IUSOM-MSTPIvayla Geneva [email protected] State University of New York - Upstate MedicalEmily Gilbert [email protected] University of Mississippi Medical CenterGeorge Glenn [email protected] MUSC College of Graduate StudiesBenjamin Goldenson [email protected] Northwestern University Feinberg School of Medicine Kathleen Green [email protected] Northwestern UniversitySarah Greene [email protected] Washington University School of MedicineSean Gu [email protected] University of IowaMichael Guo [email protected] Harvard UniversityLiam Guthrie [email protected] Texas A&M Health Science CenterAlexander Guzzetta [email protected] University of Chicago MSTPDuy Ha [email protected] University of Nebraska Medical CenterKathryn Hacker [email protected] UNC-Chapel HillAmelia Haj [email protected] University of Wisconsin-MadisonSadra Hamedzadeh [email protected] University of Florida

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Gary Hammen [email protected] Washington University - St. Louis School of MedicineTrevor Hardigan [email protected] Georgia Regents UniversityChao He [email protected] University of IowaAaron Hecht [email protected] University of ChicagoMiquia Henderson [email protected] Washington University in St. Louis School of MedicineJonathan Henry [email protected] University of ChicagoBrandon Holmes [email protected] Washington University in St. Louis School of MedicineJoel Howell [email protected] University of Michigan Medical SchoolHedvig Hricak [email protected] Memorial Sloan Kettering Cancer Center (MSKCC)Cindy Hsu [email protected] Hospital of the University of PennsylvaniaMuhan Hu [email protected] University of Alabama at BirminghamTravis Hull [email protected] University of Alabama - BirminghamHolly Humphrey [email protected] University of ChicagoAndy Hung [email protected] Northwestern UniversityJack Hunt [email protected] University of Wisconsin School of Medicine and Public Health Alan Hutchison [email protected] University of ChicagoBianca Islam [email protected] Georgia Regents University - Medical College of GeorgiaStephanie Jackson [email protected] Saint Louis University School of MedicineJennifer Jacobsen [email protected] University of ChicagoDavid Jacoby [email protected] Oregon Health & Science UniversityBapu Jena [email protected] Harvard UniversityAndrew Jones [email protected] Saint Louis UniversityAmy H. Kaji [email protected] Harbor-UCLA Medical CenterVenkat Kakollu [email protected] Brookdale University Hospital and Medical CenterNiranjan Karnik [email protected] Rush University Medical CenterKaren Kaul [email protected] Northshore Health SystemsWilliam Kelley [email protected] University of PennsylvaniaSean Kelly [email protected] Stony Brook University Medical Scientist Training Program Cymon Kersch [email protected] Oregon Health & Science UniversityMimi Kim Ellis Kim [email protected] University of ChicagoStephanie Kim [email protected] University of Chicago

Cynthia Kim [email protected]

Edita Klimyte [email protected] University of Kentucky College of MedicineJoel Kline [email protected] University of Iowa Carver College of MedicineJulian Klosowiak [email protected] Northwestern University Feinberg School of MedicineMary Klotman [email protected] Duke UniversityDavid Koren [email protected] University of ChicagoLisa Korn [email protected] University of PennsylvaniaNicole Kretzer [email protected] Washington University - St. Louis School of MedicineShwayta Kukreti [email protected] University of California - Los AngelesJake Kushner [email protected] Baylor College of MedicineJennifer Kwan [email protected] UICJacquelyn Lajiness [email protected] IUSMJonathan Lamano [email protected] Northwestern University Feinberg School of MedicineAwo Akosua Layman [email protected] Perelman Sch of MedicineKatie Lebold [email protected] Oregon Health & Science UniversityVictoria Lee [email protected] University of Chicago MSTPArthur Lee [email protected] Washington University - St. LouisJoseph Lee [email protected] Rush University Medical CenterCherline Lee [email protected] University of WisconsinHsin-Pin Lin [email protected] Northwestern U Feinberg School of MedicineMegan Liszewski [email protected] University of ChicagoMichael Litt [email protected] Vanderbilt University School of MedicineJillian Liu [email protected] The Ohio State University MSTPAnnie Liu [email protected] University of Pittsburgh School of MedicineAlexandra Livanos [email protected] NYU School of MedicineJason Lou [email protected] University of Southern CaliforniaEllen Lubbers [email protected] The Ohio State University- MSTPBrandon Lucke-Wold [email protected] WVU School of MedicineMark Lunderberg [email protected] University of Chicago MSTPPamela Marcott [email protected] Case Western Reserve University School of MedicineDavid Markovitz [email protected] University of MichiganMichael Marshall [email protected] Saumya Maru [email protected] Pennsylvania State University College of Medicine Mba Mba [email protected] Virginia Commonwealth University School of Medicine

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Tyler McCaw [email protected] University of Alabama at BirminghamWarren McGee warren-mcgee@ Northwestern University fsm.northwestern.eduAlexandra McMillan [email protected] Case Western Reserve University School of MedicineDanny Miller [email protected] University of KansasSteven Mittelman [email protected] Children’s Hospital Los Angeles - Donnell Society for Physician Scientists Erin Mowers [email protected] University of ChicagoRobert Murphy [email protected] Northwestern UniversityMartina Mustroph [email protected] University of Illinois at Urbana-ChampaignIan Mwangi [email protected] University of North Texas/UTSWRangarajan Nadadur [email protected] University of ChicagoDaniel Naftalovich [email protected] University of Southern CaliforniaAnh Nguyen [email protected] UNTHSCEvan Noch [email protected] Weill-Cornell Medical CenterOlga Novikov [email protected] Boston University School of MedicineKerry O’Banion [email protected] University of Rochester School of MedicineChristopher O’Conor [email protected] UNC-Chapel HillPaul Offit [email protected] Children’s Hospital of PhiladelphiaAlicia Olave Pichon [email protected] Alianza Research InternationalOlufunmilayo Olopade folopade@ University of Chicago medicine.bsd.uchicago.eduMarcia Paddock [email protected] Weill Cornell / Rockefeller / Sloan-Kettering Tri-Institutional Program in New York CityPriya Pal [email protected] Washington University - St. Louis School of MedicineAmy S. Paller [email protected] Northwestern UniversityAllyson Palmer [email protected] Mayo ClinicBrielle Paolini [email protected] Wake Forest University School of MedicineRamya Parameswaran [email protected] University of Chicago MSTPJung Park [email protected] University of Iowa Carver College of MedicineKeon-young Park [email protected] Emory University/Georgia Institue of TechnologyDipal Patel [email protected] Northwestern University

Erik J Peterson [email protected] University of Minnesota - Minneapolis School of Medicine -

Internal MedicineJesse Platt [email protected] University of PennsylvaniaCatherine Poholek [email protected] University of Alabama -BirminghamClaire Pomeroy [email protected] Albert and Mary Lasker FoundationJonathan Power [email protected] Washington University - St. LouisAaron Proweller [email protected] Case Western Reserve University School of Medicine - Internal MedicineSamuel Quaynor [email protected] Georgia Regents UniversityUsha Raj [email protected] University of Illinois at ChicagoMahil Rao [email protected] Washington University - St. Louis School of MedicineTyler Rasmussen [email protected] University of IowaKelly Regan [email protected] The Ohio State University College of MedicineJalees Rehman [email protected] University of Illinois at ChicagoTheresa Relation [email protected] The Ohio State University College of MedicineJennifer Rha [email protected] Emory School of MedicineChris Rishel [email protected] The University of ChicagoAlicia Rizzo [email protected] UIC College of MedicineStephanie Robert [email protected] University of Alabama at BirminghamJorge Rodriguez-Gil [email protected] University of Wisconsin School of Medicine and PubJackeline Rodriguez- jrodriguez-smith@ NIAMS Smith student.uchc.eduIan Roundtree [email protected] University of ChicagoDavid Russler- [email protected] Washington University School of Germain MedicineGabriel Salzman [email protected] University of ChicagoNicelio Sanchez-Luege [email protected] University of Chicago MSTPAkua Sarfo [email protected] Pennsylvania State University College of MedicineArup Sarma [email protected] University of ChicagoKrishna Sarma [email protected] University of Nebraska Medical CenterKonrad Sawicki [email protected] Northwestern University Feinberg School of MedicineEric Schauberger [email protected] Children’s Hospital of WisconsinSuzanne Schauwecker [email protected] Northwestern UniversityKathryn Scherpelz [email protected] University of ChicagoWade Schulz wade. [email protected] University of MinnesotaLukasz Sewera [email protected] Loyola University Chicago Stritch

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

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10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

School of MedicineViral Shah [email protected] University of Iowa Carver College of MedicineObada Shamaa [email protected] Ohio State University College of MedicineDavid Shapiro [email protected] Northwestern University Feinberg School of MedicineMarina Sharifi [email protected] University of ChicagoMatthew Sheehan [email protected] CornellAisha Siebert [email protected] University of Rochester School of Medicine and DenRolly Simpson [email protected] Burroughs Wellcome FundKavisha Singh [email protected] Duke-National University of SingaporeEmily Slat [email protected] Washington University School of MedicineBrian Soetikno [email protected] Jennifer Stanley [email protected] University of Alabama at BirminghamDavid Stoltz [email protected] University of Iowa College of Medicine - Internal MedicineJennifer Su [email protected] Children’s Hospital Los Angeles - Donnell Society for Physician ScientistsTeerawit Supakorndej [email protected] Washington University School of MedicineLaura Swanson [email protected] UW MadisonStephanie Syc-Mazurek [email protected] University of Rochester School of Medicine and DenDaniel Talmasov [email protected] Stony Brook School of MedicineNeal Tambe [email protected] University of Southern CaliforniaBranden Tarlow [email protected] Oregon Health & Science UniversityNicholas Taylor [email protected] University of North Carolina - Chapel HillJose-Marc Techner [email protected] Northwestern UniversityMaria Themeli [email protected] Memorial Sloan-Kettering CancerCenterSamantha Thomas [email protected] University of ChicagoMike Thompson [email protected] Nation wide Children’s Hospital - Pediatric Integrated Research PathwayMelissa Tjota [email protected] University of ChicagoJeremy Treger [email protected] University of ChicagoMaria Trissal [email protected] Washington University - St. Louis School of MedicineJonathan Tucci [email protected] University of Southern CaliforniaSophia Uddin [email protected] University of Chicago MSTPIboro Umana [email protected] University of Chicago MSTP

Vaibhav Upadhyay [email protected] University of ChicagoAnisley Valenciaga [email protected] The Ohio State University

Audrey Verde [email protected] University of North Carolina at Chapel HillCesar Virgen [email protected] University of California San DiegoNicholas Vogt [email protected] University of California San DiegoJoshua Wahlstrom [email protected] Loyola University Chicago Stritch School of MedicineKevin (Xin) Wang [email protected] Clinician Investigator Trainee Association of CanadaBrian Warmus [email protected] University of Alabama at BirminghamJulia Warren [email protected] Washington University in St. Louis School of MedicineJoel Warsh Sing Sing Way [email protected] Cincinnati Children’s HospitalAlice Weaver [email protected] University of Alabama at BirminghamMason Webb [email protected] Georgia Regents UniversityDaniel Webber [email protected] University of Arkansas for Medical Sciences Brittany Weber [email protected] Brigham and Women’s Hospital-Harvard Medical SchoolSherry Cai Wen [email protected] Vanderbilt UniversityGlenn Werneburg [email protected] State University of New York - Stony Brook UniversityReid Wilkening [email protected] University of Illinois at Chicago College of MedicineChristopher Williams christopher.s.williams@ Vanderbilt University School of vanderbilt.edu MedicineChristopher Williams [email protected] Vanderbilt MSTPDanielle Williamson Tong Wu [email protected] University of Iowa hospitals & Clinic - Surgery Brian Wu [email protected] University of Southern CaliforniaCindy Yuan [email protected] University of ChicagoJaime Zelaya [email protected] Oregon Health & Science UniversityRoseanne Zhao [email protected] University of Chicago

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10th APSA Annual Meeting April 25-27, 2014Chicago, IL www.physicianscientists.org

Announcements:Members: Get Involved!

Apply for National Leadership PositionsApplications open NOW!!

Apply for the RSNA Intro to Academic Radiology ProgramApplications available now!

Take advantage of specialty-specific mentoring through our interest groupsResources available through our website: www.physicianscientists.org

Mark your calendar for APSA’s Regional Meetings!

APSA South Regional MeetingLocation TBD, Date TBD

APSA Southeast Regional MeetingEmory University, Date TBD

APSA Northeast Regional Meeting Mount Sinai School of Medicine, November 1st, 2014

APSA Midwest Regional MeetingCase Western Reserve, November 15, 2014

APSA West Regional MeetingUniversity of Southern California, November 15, 2014

Work with APSA and support our mission!For MD/PhD programs and medical schools: Become an Institutional Member today and receive a discount on membership dues for all your studentsFor residency programs: Participate in our annual residency luncheon through sponsorshipFor anyone: Sponsor the 2015 APSA annual Meeting Donate to APSA and its goal of training the future generation of physician-scientists Advertise on the APSA website, in the APSA newsletter, and at our Regional Meetings

10th APSA Annual Meeting April 25-27, 2014, Chicago, IL www.physicianscientists.org

Fairmont Chicago, Millennium Park200 North Columbus Drive

Chicago, IL 60601

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111 Deer Lake RoadSuite 100

Deerfield, IL 60015

+1-847-480-9080

www.physicianscientists.org

10th Annual Meeting • April 25-27, 2014

The Fairmont HotelMillennium ParkChicago, IL USA

Program design by Stephanie BrosiusCover photograph by Alexander Adami