proprietary and confidential - ag innovation showcase companies/2013... · 2 vive introduction...
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Vive Introduction
• Vive reformulates existing pesticides for the $46 Billion crop protection industry, creating proprietary products
• Creates new, more effective water-based products that replace organic solvents
• Field-proven performance
• First products launching in 2015
• EPA registration received
• Global IP protection – 31 issued patents
• Raised $22 M to date
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“We have to produce as much food in the next 40 years as humanity has produced in the last 8,000 years”
Jason Clay, SVP
World Wildlife Fund
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• Population growth
• Shrinking arable land
• Changing diets
• 40% of crop yields lost annually to weed, disease, and insect pressure
Crop Yields are a Worldwide Issue
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Yet Industry is Under Pressure
Regulatory Barriers
Patent Cliff
Lack of New Molecules
Shortage of Proprietary Products
Pressure from Generics 5 5 proprietary and confidential
Regulatory Pressures are Increasing
680 Products removed
from the EU market
• Solvents more toxic than common AI’s Glyphosate (Roundup), 2,4-D (Killex), many others
• China
Reducing the use of 5 standard ‘EC’ solvents by 90% in three years
• California and Europe VOC limitations restrict or prevent solvent use
Goalposts are Higher Formulations are Under Fire
Most AI’s do not disperse in water
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Facing a “Pharma-like” Patent Cliff
acetamiprid (Nippon Soda) acibenzolar-S-methyl (Syngenta) amicarbazone (ArystaLifeScience) azoxystrobin (Syngenta) bifenazate (Chemtura) cafenstrole (SDS Biotech KK) carfentrazone-ethyl (FMC Corp.) cinidon-ethyl (BASF Corp.) clothianidin (Bayer CropScience) cyazofamid (ISK Biosciences) cyclosulfamuron (BASF Corp.) cyprodinil (Syngenta) emamectinbenzoate (Syngenta) ethoxysulfuron (Bayer CropScience) famoxadone (DuPont Crop Protection) fenamidone (Bayer CropScience)
fenhexamid (Bayer CropScience) florasulam (Dow AgroSciences LLC) flufenacet (Bayer CropScience) flupyrsulfuron-methyl-sodium (DuPont Crop Protection) indanofan (Nihon Nohyaku Co.) indoxacarb (DuPont Crop Protection) iprovalicarb (Bayer CropScience) isoxaflutole (Bayer CropScience) kresoxim-methyl (BASF Corp.) mefenpyr-diethyl (Bayer CropScience) mesotrione (Syngenta) picolinafen (BASF Corp.) picoxystrobin (Syngenta) propoxycarbazone (Bayer CropScience) pyraclostrobin (BASF Corp.)
pyraflufen-ethyl (Nihon Nohyaku Co.) quinoxyfen (Dow AgroSciences) silthiofam (Monsanto) spinosad (Dow AgroSciences) spiroxamine (Bayer CropScience) sulfentrazone (FMC Corp.) thiacloprid (Bayer CropScience) trifloxystrobin (Bayer CropScience) triticonazole (BASF Corp.) tritosulfuron (BASF Corp.) zoxamide (Gowan Co.)
Active Ingredients Coming Off Patent
Active ingredients due to come off patent between 2009-2013 or that have been granted patent term extension between 2011-2015. Source: Enigma Marketing Research
$ Billions expiring in next 5 years 7 proprietary and confidential
Expensive Up to $250 million to develop a new Active Ingredient
High failure rates Efficacy and commercial risk
Long timelines 10 years from initial research to product registration
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Lack of New Active Ingredients
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Addressing Crop Protection Industry’s Key Issues
Innovative Competitive Approvable
• New products without new active ingredient
• Economics
• Efficacy
• Convenience
• Grower safety
• Avoid formulation issues
• Environmental safety
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Products
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Vive Products and Technology
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Vive makes water-based formulations
of post-patent active ingredients that
are better than existing products
Better field performance
No solvents / VOCs
Great economics
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Active Ingredient (AI) Allosperse Vive New Product
Vive Technology
Not soluble in water Encapsulates AI in a water dispersible (non-toxic) structure
Encapsulated AI dispersed in water
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Insecticides
• More effective so farmer saves money by reducing sprays: • Long lasting • Can be sprayed
with fertilizers
Better farmer ROI
Better manufacturer ROI
Clear path to registration
Demonstrated Product Value Supported
by Extensive Field Trials
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Fungicides • Farmer makes
money: increases crop yield
• Cures the disease, unlike some other products
• Prevents disease
Herbicides
• More effective at low rates so manufacturer reduces cost of goods sold
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Revenue: Value Share
• Vive revenue based on
- Product developed by Vive
- Allosperse shipped to customer for incorporation in their formulation OR
- Complete final product shipped from Vive’s toll manufacturer to customer
• 2 signed distribution contract term sheets and 12 in negotiation with manufacturers and distributors
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Manufacturing - Simple, Scalable, Tollable
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Step 1 - Make Polymer Step 2 – Turn Polymer into Allosperse
Ready to Toll
Step 3 – Combine and Package
Ready to Toll
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• 31 issued patents (first expiry 2025)
• 33 patents pending
• 8 families in the US and internationally
• New products via patentable reformulations
Four Levels of IP Protection
Patent Cliff
Ongoing IP Generation 16
Product IP
Application IP
Process IP
Composition of Matter IP
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Honors and Awards
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2012: Highly Commended for Best Formulation Innovation, Agrow Awards
2012, 2010: Winner, Canada’s Top10TMin Cleantech
2011: Nominated for Best Formulation Innovation, Agrow Awards
2012, 2011: New York Venture Summit – Best Cleantech
2011: Recipient of American Chemistry Council’s Responsible Care Performance Award
2010: Frost & Sullivan’s North American Technology of the Year Award for Vive’s Encapsulation Technology Innovation
2009: Named one of Deloitte’s Technology Green15TM
2009: Winner, Canadian Business Magazine’s Clean15TM Competition
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Corporate Information
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Keith Thomas CEO
Entrepreneur, project management and corporate finance; Booz Allen, Citigroup, BASc (Toronto), MA (Toronto), MBA (Columbia)
Darren Anderson CTO
Founding president, 7 issued patents, 39 pending applications, 10 refereed papers, over 40 conference presentations and publications, PhD (Toronto)
Flavio Campagnaro Chief Manufacturing Officer
Senior process engineer, scaled large environmental plants; Bennett Environmental, BASc (UBC), PEng
Skip Campbell Chief Commercial Officer
Boston-based M&A and advisory for high-tech industries, consulting and VC experience, BA (Williams), MBA (Toronto)
Ken Yoon CFO and EVP Corp Development
Life sciences venture capitalist, consulting and accounting; VenGrowth, Ernst & Young, BSc (Western), LLB (Queen’s), MBA (Toronto), CA
Management
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Supplemented by 10 advisors with experience at Syngenta, BASF, DuPont, Dow, FMC ,etc.
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Neil Reid Chair
Co-founder, MDS Sciex
Charlie Fischer
Director
Former CEO, Dow AgroSciences; Former Chair, CropLife America and CropLife
International
Warren Libby Director
Former President, Syngenta Canada; Former Chairman, Crop Protection Institute of Canada
Bill Lambert Director
Chairman, Ag Growth International; Former Partner, TD Capital
Mark MacDonald Director
Former VP, Teachers Private Equity; significant board experience
Directors
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2007–2013 - $22 M Raised Expansion Capital
Product Development
Initial Biology
Agreements Drive Value
Product Launches
CO
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Field Validation
Scalable, Tollable, Cost
Effective Manufacturing
EPA Registration
The Vive Opportunity
$46 Billion global market opportunity with assured demand
Disruptive, patented, green technology addresses industry needs
Imminent value creation events: commercial deals, registrations and
product launches
Strong management team and directors
Expansion into additional markets
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Keith Thomas, CEO
700 Bay Street, Suite 1100
Toronto, ON M5G 1Z6
416 260-8889 x224
www.vivecrop.com
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