radiation toxicity antidotes

8/3/2019 Radiation Toxicity Antidotes

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Radiation Toxicity Antidotes(C) 2010 by John W. Apsley, II, MD(E), DC -www.doctorapsley.com

Q: What can I do now to protect myself from nuclear fall-out arriving from themeltdown of Japan's nuclear power plants?

A: History has taught us to "hope for the best," but "plan for the worst" andto educateoneself better than the politicians or their official scientific spokespersons!

The radioactive metals uranium, plutonium, cesium and strontium are of primary concern, rightalongside radioactive iodide. Once lodged into our tissues, all will induce lethal tissue ionization,which over decades will derange genetic functions and kill many cells. To avoid this, the metals needto be removed from the cells. Specifically over the long term, radioactive cesium will concentrate inthe fatty tissues, radioactive iodine in the thyroid gland and ovaries, strontium in theboneand uranium and plutonium in the liver. For North America, over time this may/will lead tosignificantly greater levels of cancer or alternative forms of chronic degenerative disease in ourchildren and young adults via the Petkau Effect.(A), (B), 18, 19, 22

The fallout will present in THREE forms or threats to our health:

The first will be the immediate airborne threat over the next several weeks. Depending upon which"starting date" you use (the date of the first detection of radioactive cesium being airborne or whenhelicopter crews from the USS Ronald Reagan were first documented to have been exposed, i.e.,March 14th, 2011), we can expect the West Coast of the U.S. to begin to receive at least minimal

fallout within 7 to 10 days or possibly on the weekend of March 19th - 20th, 2011 (see nucelar falloutmap above). This may mean that by the 1st of April, the entire region ofNorth America willhave undergone the first round of fall-out exposure, even if at undetectable levels in many areas. Asthe upper air currents repetitively cycle around the globe over and over again, the stock ofradioactive airborne materials will fall out as part of normal rainfall or as simple dust particles. Foran enlargement of the above map, see: https://reader009.{domain}/reader009/html5/0507/5aef83

To track up to the minute levels of excessive radiation here in the U.S., and/or join in


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this worthy effort, see:http://www.radiationnetwork.com/

The next threat will be when it enters into our water supply and food chain over the many weeksand perhaps months ahead.

The last threat stems from the extremely low levels of radiation which become ever present due toradioactive materials burrowing into our tissues. This will be by far the more deadly form ofradiation poisoning to those living in North America, and is properly calledThePetkau Effect. The Petkau Effect is in many ways identical to what happens when undergroundfires ignite that cannot be extinguished. Indeed, there are locations around the worldwhere abandoned coal mines went ablaze and simply cannot be put out. Some of these havesmoldered slowly out of control for 30 years or more. The same may occur within our very ownbodies when radioactive iodide, uranium, plutonium, cesium and strontium enter our lungs as webreathe or in through our digestive tract when we eat or drink contaminated foods or water.ThePetkau Effect applies to chronic low level exposures and accrues over a long

time frame because these radioactive materials will continue to emit toxic ionizing radiationfor thousands of years.(A), 22

You don't need to worry about acute spikes in radiation which are fleeting, since few will everexperience such an event. You should be concerned about tiny scattered particles that settle into ourtissues undetected, and not worry about amounts sufficient to trigger Geiger Counter alarms goingoff at airport check stations. The tiny amounts of exposure which are more likely to occur give offconstant ionizing radiation that burns us at the molecular level over many years before causing adiagnosable issue.19

Also, the cloth-paper masks that many people use around their faces are useless to protect fromthese tiny particles. Sorry folks! You would need advanced charcoal filters that are quite bulky andmore expensive to achieve any meaningful "up-front" protection for your lungs. Therefore, beforewarned that any official positions claiming that, "only low levels of radiation have been detectedand therefore pose no real health threat to the American public," are tainted and should be viewedas phraseology more properly akin to either misinformation or outright propaganda.(B), 18

For scientists, thePetkau Effectmay be illustrated as follows:

A long term exposure of extremely low radiation (i.e., one-ten millionth of a rad) was found to be100 BILLION timesMORElethal than a short term exposure to exceedingly high level radiation(i.e., 10,000 rads per minute). As it turns out, Petkau discovered-- that at exceedingly high radiationlevels, the abundant free radicals generated in tissues tended to cancel each other out before theycould do cellular damage. But at extremely low levels of radiation, these same free radicals -produced in minuscule quantities - remain unchecked. And any steady stream of unchecked free-radicals will efficiently and lethally cleave lipid cellular membranes like a hot knife slicing throughbutter once they overwhelm and exhaust cellular antioxidant defenses. This dramatically illustratesthe non-linear aspects of dose (rads) to lethality. Most scientists specializing in this field are


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unaware of this fact. And most think strictly in terms of genetic damage, while the above presentsits lethal affects upon cell membranes and only secondarily to the genetic core.18

SHORT TERM ANTIDOTES:

1. N-Acetyl-Cysteine (NAC) is the most powerful short term quencher of ionizing radiation. Foradults (weighing above 150lbs) , it is taken in dosages of up to 500mg daily. For younger adultsweighing 100lbs to 149lbs, 400mg daily affords adequate protection. In children weighing less than100lbs, but above 50lbs, 200mg daily is a suitable dose. For infants, toddlers or children weighingless than 50lbs, 50mg to 100mg daily may be used in juice, as long as no sensitivity to NAC arises(i.e., light skin rashes). In this manner, NAC may be used daily on an indefinite basis, as it is aharmless amino acid our bodies will use. It is also an excellent remover of toxic metals fromthe body, such as radioactive uranium. Rarely, some adults are sensitive to NAC, so be aware ofspecial advisories regarding its long term use.6, 7

2. Liquid iodide is also a first line of defense mineral supplement, since it can out-competeradioactive iodide from entering into our bodies.11 Up to 1,000mcg daily are used for several shortweeks.Kelp, Irish Moss or Dulse can then replace the liquid iodide. For adults, up to 5 tabletsper meal of any one of these may be wise. But for folks allergic to seafoods or iodide, taking Kelp orliquid iodide is not advised. Kelp is also an excellent remover of toxic metals from the body,especially if high fiber intake is also being incorporated into the diet.9, 10

3. Chlorella (and other blue green algae) is a superior protector and remover of radioactive

metals from the body contains no less than 20 superior neutralizers to-- radioactive poisons. 5 permeal (250mg each) is a great dose for adults, 3 per meal for young adults and children, and 1 permeal for the very young. Make sure the Chlorella brand you buy has the outer cell wall "cracked" forbest absorption. More may be taken, but it is suggested to not exceed 40 tablets daily.3, 4, 29

4. High quality bone meal (rich in Calcium & Strontium Hydroxyapatite) will also protectagainst radioactive strontium poisoning. 3 per meal as labeled is suggested for adults, young adultsand children, and 1-2 per meal for the very young.12

5. Natural Vitamin E Complex - To stop cell membrane destruction. 800iu per day is anexcellent dose for average adults, and 400iu per day for young adults and children. Toddlers andinfants may be given 100iu per day in juice. (Side Note:Wheat Germ OilCoQ10(H) andMelatonin...)

6. Consuming High fiber and seaweed dishes on a regular basismust be used to maximizethe best effects of the above tools. These will help insure removal of toxic radioactive metals from


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the body. On rare occassions, if exposures to radioactive metals become chronic or reaches what areconsidered high levels,baking soda is an efficient means to remove these metals quickly(especially uranium). For adults under doctor supervision, and when deemed medical necessary, upto 1 teaspoon of baking soda can be taken 2 hours after each meal, plus upon rising and uponretiring, for a maximum total of 7 teaspoons daily over a two week period.14, 15

LONG TERM ANTIDOTES (for maintenance):

Bone Meal (protects against radioactive Strontium); Chlorella (protects against most radioactive metals); Kelp (protects against radioactive iodide and other radioactive

metals); Probiotics - several billion per meal in capsule format (protects

against radioactive Strontium).16, 17

Examples of Protection Schedules According to Body Weight & Budgetary Allowances

Q: What is the one, least expensive method to protect oneself from radioactive fall-out?

Q: What are the top three tools to protect oneself from initial stages of radioactivefall-out?

A: NAC, Kelp and Chlorella. ( Sea Weed and Sea Fungus and Sea Vegetables at a asian market willas well be considered )

Average adults (weighing +150lbs): 500mg NAC at breakfast, 5 Kelp tablets &5 Chlorella tablets with each meal.

Young adults and larger children (weighing 100lbs - 149lbs): 400mg NACat breakfast, 3 tablets of Kelp & 3 Chlorella tablets with each meal.

For smaller children (weighing 50lbs - 99lbs): 200mg NAC at breakfast, 1tablet of Kelp & 1 tablet of Chlorella with each meal sprinkled into juice.

For the very young (weighing less than 50lbs): 50mg to 100mg NAC, 1 tabletKelp & 1 tablet Chlorella daily sprinkled into juice.


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Q: What are the top four tools to protect oneself from initial stages of radioactive fall-out?

A: NAC, Kelp, Chlorella and Vitamn E.

Average adults (weighing +150lbs):500mg NAC at breakfast, 5 Kelp tablets &5 Chlorella tablets with each meal + 1 cap Krill Oil.

Young adults and larger children (weighing 100lbs - 149lbs):400mg NACat breakfast, 3 tablets of Kelp & 3 Chlorella tablets with each meal + 1 cap Krill Oil.

For smaller children (weighing 50lbs - 99lbs):200mg NAC at breakfast, 1tablet of Kelp & 1 tablet of Chlorella with each meal crushed & sprinkled into juice+ 1 cap Krill oil squeezed & blended into milk or juice.

For the very young (weighing less than 50lbs):50mg to 100mg NAC, 1 tablet

Kelp & 1 tablet Chlorella daily crushed & sprinkled into juice + 1 cap Krill Oilsqueezed & blended into milk or juice.

Q: If the lipid membranes are the sole issue, what are the best tools to preventmembrane damage during initial stages of contamination?

A: Many physicians would chose R-alpha lipoic acid (thioctic acid) as their first choice since it will

powerfully retard lipid membrane ionization. Lipoic acid tends to bind metals and deposit theminto the nucleus of cells (as opposed to removing them from the body).24, 26Therefore, it is best touse Krill oil, or 'reduced' co-enzyme Q10 [CoQ10(H)], or Vitamin E and Melatonin to accomplish

a better end result. Krill oil, CoQ10(H) and Vitamin E would neutralize the ionizing effects onsite,while Melatonin would also seek to safely remove the offending radioactive particle from the body(via the bile route of elmination provided there is adequate fiber).7, 21, 23, 25 In order of strength,Krill Oil reigns supreme, then CoQ10(H), then Melatonin, and finally Vitamin E. But for thekinds of low dose exposures North America is likely to receive, natural Vitamin E complex shouldprovide adequate protection if taken ahead of exposures. Melatonin is a superior multitaskingnutrient and so serves purposes beyond the others. Therefore, this is a prudent tool to include ifbudget allows. In summary, budget prudently for the suggested schedules below, and if necessary,

eliminate Krill oil in favor of Vitamin E, eliminate NAC in favor of extra Chlorella, and substituteSpirulina over Chlorella to save money as necessary.

Average adults (weighing +150lbs): 500mg NAC + 800iu Natural Vit. E atbreakfast + 1 cap Krill oil; 5 Kelp tablets, 5 Chlorella tablets with each meal; and10mg Melatonin at bedtime.

Young adults and larger children (weighing 100lbs - 149lbs): 400mg NAC+ 400iu Natural Vit. E at breakfast + 1 cap Krill oil; 3 tablets of Kelp & 3 Chlorella


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tablets with each meal, and 3mg Melatonin at bedtime.

For smaller children (weighing 50lbs - 99lbs): 200mg NAC + 200iu NaturalVit. E at breakfast + 1 cap Krill oil squeezed & mixed into milk or juice; 1 tablet ofKelp & 1 tablet of Chlorella with each meal; and 1mg Melatonin at bedtime.

For the very young (weighing less than 50lbs): 50mg to 100mg NAC, 100iuNatural Vit. E, 1 cap Krill Oil squeezed & mixed into milk or juice, 1 tablet Kelp &

1 tablet Chlorella daily sprinkled into juice; and 500mcg chewable Melatonin atbedtime.

Q: In view of the long term consequences from nuclear power plant meltdown, whatmaintenance schedules should be incorporated to best help us all prevent cancerdecades down the road?

A: Kelp, Spirulina,NaturalVitamins C & E, high-quality Bone Meal, high-endprobiotics(acidophilus), and Melatonin + selenium along with myGetting Started tab above for completemenu planning.

Average adults (weighing +150lbs): 400iu Natural Vit. E plus 1 capsule highpotency Probiotics at breakfast; 2 Kelp tablets, 3 Spirulina tablets & 2 Bone Mealtablets with each meal; and 10mg Melatonin at bedtime with 400mcg seleniumfrom selenomethionate.Also, one effervescent Vitamin C drink is to be ingesteddaily.

Young adults and larger children (weighing 100lbs - 149lbs): 400iuNatural Vit. E plus 1 capsule high potency Probiotics at breakfast; 2 tablets ofKelp, 2 Spirulina tablets & 2 Bone meal tablets with each meal, and 3mgMelatonin at bedtime with 400mcg selenium from selenomethionate. Also,one effervescent Vitamin C drink is to be ingested daily.

For smaller children (weighing 50lbs - 99lbs): 200iu Natural Vit. E plus 1capsule high potency Probiotics at breakfast; 1 tablet of Kelp, 1 tablet of Chlorellaand one Bone Meal with each meal (all sprinkled into juice as appropriate); and1mg chewable Melatonin at bedtime with 100mcg - 200mcg selenium fromselenomethionate.Also, one effervescent Vitamin C drink is to be consumed daily.

Chewable Vitamin C tablets may be substitutedIFthe brand isLOWin sugar.

For the very young (weighing less than 50lbs): 100iu Natural Vit. E, 1 tabletKelp & 1 tablet Chlorella plus 1 capsule high potency Probiotics plus 2 Bone Mealcapsules opened & sprinkled into juice daily; and 500mcg chewable Melatonin atbedtime with 50mcg selenium from selenomethionate.Lastly, one effervescentVitamin C drink is attempted to be given daily.Chewable Vitamin C tablets maybe substitutedIFthe brand isLOWin sugar.


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Best Long Term Protocol: I (Dr. Apsley) have an extended family, with childrenranging in ages from 34 down to 11, and three grandkids ages 4 & 2 years of age. Myrecommended maintenance schedules to my family are provided below:

Average adults (weighing +150lbs): 250mg NAC + 400iu Natural Vitamin Eplus 1 capsule high potency Probiotics & 3 capsules Krill Oil at breakfast; 2 Kelptablets, 3 Chlorella tablets & 2 Bone Meal tablets with each meal; and 10mgMelatonin at bedtime with 400mcg selenium from selenomethionate. Also, one tothree effervescent Vitamin C drinks are to be ingested daily.

Young adults and larger children (weighing 100lbs - 149lbs): 250mg NAC+ 400iu Natural Vit. E plus 1 capsule high potency Probiotics & 2 caps Krill Oil atbreakfast; 2 tablets of Kelp, 2 Chlorella tablets & 2 Bone meal tablets with eachmeal, and 3mg Melatonin at bedtime with 400mcg selenium fromselenomethionate. Also, one effervescent Vitamin C drink is to be ingested daily.

For smaller children (weighing 50lbs - 99lbs): 200mg NAC + 200iu NaturalVit. E plus 1 capsule high potency Probiotics & 1 cap Krill Oil at breakfast; 1 tabletof Kelp, 1 tablet of Chlorella and one Bone Meal with each meal (all sprinkled intojuice as appropriate); and 1mg chewable Melatonin at bedtime with 100mcg -200mcg selenium from selenomethionate. Also, one effervescent Vitamin C drinkis to be consumed daily. Chewable Vitamin C tablets may be substitutedIFthebrand isLOWin sugar.

For the very young (weighing less than 50lbs): 50mg to 100mg NAC, 100iuNatural Vit. E, 1 tablet Kelp & 1 tablet Chlorella plus 1 capsule high potencyProbiotics plus 2 Bone Meal capsules opened & sprinkled into juice daily; and500mcg chewable Melatonin at bedtime with 50mcg selenium fromselenomethionate. Lastly, one effervescent Vitamin C drink is attempted to begiven daily.Chewable Vitamin C tablets may be substitutedIFthe brand isLOWin sugar.

Q: What can I do to antidote my exposures to radiation therapy?

A: Radiation toxicity from any source, including the after effects of radioablative therapy, can bedetoxified or lessened and even reversed by the use of colloidal Regeneration Factors orcRFsTM.38,39, 40 Just be sure to take afterradioablative therapy has completed or is placed on hold.cRFsTM derive from select raw foods which contain high amounts ofRNAor

nucleoproteins as found in organ meats, nuts & seeds, sprouts, food-grade algae and bee pollen.(C) Folks who tend to get gouty cannot take high amounts of these select foods sources, but usuallycan handle some intake providing the source is raw and not cooked. For example, food grade algaeproducts, which are raw, can serve such folks well if lots of SAW is being ingested as well. Allprotocols for diet under this website are high in these factors, i.e., SAW plusRNA-cRFsTM.

For an average size adult, the foremost factors one should focus on to reduce the toxicafter affects from radioablative therapy are:


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A. NAC (as above);6

B. Chlorophyll (found in sea vegetables, and richest in Chlorella or Spirulina - 5 per mealfor adults);3, 4

C.cRFsTM - As found in Chlorella, Spirulina and organic organ meats such as liver, spleen

and thymus in freeze-dried format. When taking capsules of organic

glandulars withoutalgae products as above, up to a combined 12 to 18 capsules per dayfor an average adult is optimal. When taking with algae products

according to the above dosages, cut this amount in 1/2);1, 2

D. Krill oil orVitamin E Complex (including delta and gamma tocopherols andtocotrienols taken as above). Krill oil is300 times more powerfulthan Vitamin E

and34 times more powerfulthan CoQ10 for reducing free-radical damage, mainly tocellular lipid membranes in the body;7, 21, 27, 28

E.Lipoic acid as R-alpha lipoic acid (100mg three times daily for adults, 100mg daily foryoung adults and children, 25mg - 50mg daily for the very young - when

no toxic metal particles are involved, just gamma rays);7

F. Melatonin (5mg to 20 mg at bedtime for adults,1mg to 3mg for children and youngadults respectively);5

G.Reduced CoQ10 or Ubiquinol (100mg daily for adults, 50mg per day forsmaller adults and children, 25mg daily for the very young);7, 21

H.Vitamin C and Quercetin (1,000mg three times daily and 100mg three timesdaily respectively);7, 21

I. Organic Selenium as selenomethionateor when grown into kelp or other foods(400mcg - 600mcg daily for adults, 200mcg - 400mcg daily for young adults, 200mcgdaily for children, 50mcg - 100mcg daily for the very young).21

If any confusion remains, your holistic trained doctor can adjust the above dosages down or upaccording to your weight.

Strongly suggested additions to the diet:

All manner and selections of sea vegetables (seaweed dishes) are the first choice.9, 10 Additionally,two herbal medicines which are very potent antidotes to high radiation exposure are: high-


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qualityAloe vera juice 20 (for any radiation burns, internal or external), and Noni juice13 (Morinda citrifolia).Also, eliminate all refined sugar from the diet. Lastly, emergingevidence suggests that one species of structured water (Fullerene-C60) may be able to protectnormal cells from harmful effects of radiation therapy while simultaneously enhancing results ofradiation therapy.8 More studies are needed to confirm this theory.

In the unlikely event of an emergency concerning acute radiation poisoning, bakingsoda may be used when directly exposed to high levels of radioactive nuclei

(americium, cesium, plutonium, strontium, uranium, etc...):

Under a doctor's supervision,baking soda is the tool of choice to remove these toxicmetals from the body quickly. Up to 7 teaspoons daily for adults may be used short-term (over 6 consecutive days) to accomplish thorough decontamination, with route &rate of adminstration carefully considered by the physician. Now, couple this protocol tothe lipid membrane protocol listed above with added probiotic supplementation and asappropriate use Aloe and Noni juice with a strict diet of no refined carbohydrates, and plenty ofSAW.7, 12, 14, 15, 21, 23, 25Where run-a-way inflammation has taken hold, quadruple NAC intake& follow the natural aspirin, omega 3 & 6 oil protocolswith cherry concentrate, curcuminand boswellia (see: http://doctorapsley.com/AspirinandSynergistsforCancer.aspx ).

Alternatively, intravenous administration of 5% baking soda (in 500cc), glutathione(2gm), reduced CoQ10 (300mg), sodium ascorbate (10gm), Omega 3 oils (2gm), NAC (5gm) andselenium (2mg) can be administered daily over the course of a week or two, with good successwhere patient is incapable of ingesting oral supplements. Patient should sip Aloe and Noni juice adlib.

To those who may dissent from the above science:

Currently there are a group of esteemed physicists who are suggesting that low levels of radiationfrom any source, can be beneficial. They are citing some very compelling evidence which suggests

that cancer rates can actually go down, not up, with long term, low level exposures to toxicradioactive nuclei such as cobalt or cesium. They also link this kind of radiation to the principles of"hormesis" something of which Eclectic Physicians are quite familiar with. And finally, they citemineral rich hot springs which are known to emit low level radiation from a naturally occurringradioisotope called radon.30 In fact, the hot springs in Ikaria, Greece and select hot springs inMisasa Hot Springs District of Japan are famous for healings reportedly arising from proper use ofthese therapeutic waters.

Eclectic physicians often specialize in BioEnergetics, the Fourth Pillar to The RegenerationEffect. And what these experts will tell you is that select low levels of radiation thatdisrupt cell membranes will trigger attempts in tissues to regenerate the damage,

which is termed autophagy. Just enough autophagy with just enough antioxidants andother essential factors like oxygen and you are, "In like Flint." But too muchautophagy with too little antioxidants or under conditions of hypoxia, and you runinto cancer, premature cellular death or autoimmune disease. Therefore, only looking atcancer death rates without the other diseases that can substitute in cancer's place, is misleading tosay the least when examining radiation hormesis.

For example, since WWII, over 555,000 TRILLION picocuries of radiation have been released intothe Earth's biosphere with a half life exceeding 10,000 years of toxicity.18 This helps to explain thedramatic rise, for example, of Cancer, but also Hashimoto's Disease, Hypothyroidism Type 2,Diabetes Type 2, Colitis, Crohn's Disease, Lupus, Scleroderma, ALS, MS, R.A.,


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Osteoporosis, Fibromyalgia, Chronic Fatigue Syndrome, Universal Allergic Reactors, Alzheimer'sDisease, infertility, Autism, Low Birth Weight, the rise in Birth Defects, Infant Failure to ThriveSyndromes (i.e., SIDS), etc... These emerging studies so far do nothing to track thesesubstitutes for cancer which may arise from chronic, low level radiation poisoning.Forfurther confirmation of the above, according to Gabriel Cousens, MD, in his book, Conscious Eating(regarding the Chernobyl incident), reports:41

"(A top expert, Dr. Ernest J. Sternglass of the University of Pittsburgh) presented at the First Global

Radiation Victims Conference in New York in September 1987, impressively conveyed theseriousness of the radiation problem.The infant mortality rate following the arrival of theChernobyl fallout in early May of 1986 showed a 54% increase in June 1986 in thePacific region of the United States.Washington State had the highest rate in theregion with a245% increase in deaths per thousand live births. California was nexthighest with a48% increase in infant mortality as compared to June of the year

before. These high rates lasted for July and August. Massachusetts led the nation in post-Chernobyl increase of infant mortality rate with an increase of 900% per thousandlive births! Massachusetts also had a decline of 70% in newborns. The rate of live birthsalso decreased throughout the country in response to the Chernobyl fallout. The US fertility ratedecreased 8.3% in July and August to the lowest level ever observed in United States

history."

So the above illustrates what happens when everyone is looking in the wrong direction, even if forthe right reason. Therefore in my book, there is no such thing as safe, low level exposures to "man-made" sources of radiation. Indeed, any short term benefits will be offset by untoward effects in thefuture, even if we are too ignorant at present to catch it in advance. Without the proper referencepoints to link back such differing kinds of data, confusion will prevail when trying to gauge radiationmorbidity and mortality statistics. So, what are the proper reference points that will tell us here andnow if low levels of any kind of radiation are potentially beneficial to human tissues? Thesereference points derive from those discovered by Gilbert N. Ling, and two other experts inBioEnergetics, relating to seven factors:31, 32, 33

Does the radiation improve aerobic metabolism of the cellor tissue or lead to healthy cell or tissue regeneration whichdisplays optimal aerobicmetabolism?

Does the radiation improve the pH profile of the externaland internal milieu of the cell or tissue or lead to healthycell or tissue regeneration whichdisplays optimal pH?

Does the radiation improve the structured water (polarizedmultilayers of water or PM water) within the cell or lead tohealthy cell or tissue regeneration which display optimalPM water?

Does the radiation improve or harm the normal spectrum of


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mineral elements in the cell and their proper locations orlead to healthy cell or tissue regeneration which displaysoptimal mineral reserves?

Does the radiation improve or harm the special proline-rich-peptides within cells that are the scafolding to the PM

water in the cell or lead to healthy cell or tissueregeneration which displays optimal proline-rich-peptidereserves?

Is the 'Phase Angle' of the body improved by the radiationexposure or lead to healthy cell or tissue regeneration

which displays optimal Phase Angle? And finally, is the negative millivolts of the cell and tissues

improved from the radiation exposure or lead to healthycell or tissue regeneration which displays optimal

millivolts?

Physicists who doubt that man-made low level radiation cause harm must verify theiropinion by addressing the above questions. Until they do, they stand on inadequatelycircumspect data points.

For a comprehensive, well-documented report on U.S. government official misinformationcampaigns and outright propaganda policies regarding radiation threats to the American public,

see:http://www.laka.org/docu/boeken/pdf/6-01-4-80-46.pdf

Always restore the body's own self-healing system first. Then the "footing" of all othernatural healing tools employed will have the advantage of driving forward from the

high-ground. cRFsTM are key to this strategy when dealing with all radiation toxicitysituations, as is abundant SAW and plenty of fresh air. With so much to gain, and solittle to lose, why not at least consider a sound maintenance schedule for you and yourfamily?

References:

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(A). Abram Petkau, PhD, is a former nuclear physics researcher assigned to Atomic Energy ofCanada, Whiteshell Nuclear Research Establishment in Pinowa, Manitoba during the early 1970's.

Also see:http://en.wikipedia.org/wiki/Petkau_effect

(B). For a complete review on low-level radiation dangers and cover-ups, please see: Gould JM,Sternglass EJ, Mangano JJ, and McDonnell W.The Enemy Within.Four Walls Eight Windows,New York, NY

(1996).

(C). See upcoming eBookThe Regeneration Effect, Volume 1, for complete documentationcovering this subject and the items listed above. See: http://doctorapsley.com/EBooks.aspx

________________________________________________

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13. Qiao ZS, Wu H, Su ZW. [Comparison with the pharmacological actions of Morinda officinalis,Damnacanthus officinarum and Schisandra propinqua].Zhong Xi Yi Jie He Za Zhi. 1991 Jul;11(7):415-7, 390.

14. Henge-Napoli MH, et al. Efficacy of 3,4,3-LIHOPO for reducing the retention of uranium in ratafter acute administration. Int J Radiat Biol. 1995 Oct;68(4):389-93.

15. Fatome M. [Management of accidental internal exposure].J Radiol. 1994 Nov;75(11):571-5. Andsee: http://amarillo.com/stories/022708/bus_9691333.shtml.

16. Chaitow L, Trenev N. Probiotics. Thorsons, Hammersmith, London, 1990;pp. 15, 118-20 & 144.

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18. Null G, et al. What physicians should know about the biological effects of ingested fissionproducts. Townsend Letter for Doctors & Patients.Aug/Sep 1993;(121/122):812.

See: http://www.laka.org/docu/boeken/pdf/6-01-4-80-46.pdf page 21, second paragraph.

19. Petkau A. Effect of Na-22 on phospholipid membranes.Health Physics 1972 Mar. (See referenceabove.) Also see: http://www.no-nukes.org/prairieisland/hilolevel2.html

20. Bakuridze AD, et al. [Radio protective drug production from fresh leaves of Aloe arborescensMill]. Georgian Med News. 2009 Jun;(171):80-3.

21. Wambi CO, et al. Protective effects of dietary antioxidants on proton total-body irradiation-mediated hematopoietic cell and animal survival.Radiat Res. 2009 Aug;172(2):175-86.

22. Graeub R. The Petkau Effect,2nd edition, Four Walls Eight Windows, New York, NY (1994).

23. Bells M, Melatonin reduces uranium-induced nephrotoxicity in rats.J Pineal Res. 2007 Aug;43(1):87-95.

24. Aposhian HV, et al. Vitamin C, glutathione, or lipoic acid did not decrease brain or kidneymercury in rats exposed to mercury vapor. Toxicol Clin Toxicol, 2003;41(4):339-47.

25. Reiter RJ, et al.Mechanisms for the Protective Actions of Melatonin in the Central NervousSystem.Annals of the New York Academy of Sciences 2001;939:200-215.

26. Hultberg G, Andersson A, Isaksson A. Lipoic acid increases glutathione production and enhancesthe effect of mercury in human cell lines. Toxicology, 2002 Jun14;175(1-3):103-10.

27. See: http://articles.mercola.com/sites/articles/archive/2008/08/14/is-krill-oil-48-times-better-than-fish-oil.aspx

28. Kidd PM. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings andstructural-functional synergies with cell membrane phospholipids.Altern Med Rev. 2007 Sep;12


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(3):207-27.

See: http://krilloil.com/research-3.html

29. Apsley J. The Regeneration Effect: A Professional Treatise on Self Healing, Volume 2, GenesisCommunications, LLC, Northport, AL, 1996;p.75. ISBN: 0-945704-02-X.

30. See: http://townhall.com/

columnists/anncoulter/2011/03/16/a_glowing_report_on_radiation/page/full/

31. Ling GN. Life at the Cell and Below - Cell Level: A Hidden History of a Fundamental Revolutionin Biology. Pacific Press, NY. 2001.

32. Tennant J. Healing is Voltage: The Key to Pain Control and Chronic Disease, Tennant Institutefor Integrative Medicine and Pain Control, Irving, TX. 972-580-1156.

See: http://www.tennantinstitute.com/TIIM_MAC/Welcome.html

33. The Phase Angle is the angle between resistance and impedence, and is measured in degrees.See: http://www.rjlsystems.com/bia-disease-states.shtml

34. Rotkovska D, et al. The radioprotective effects of aqueous extract from Chlorococcal freshwateralgae (Chlorella kessieri) in mice and rats.Strahlenther Onkol. 1989;165:813.

35. Vacek A, et al. Radioprotection of hemopoisesis conferred by aqueous extract from Chlorococcalalgae (Ivastimul) administered to mice before radiation.Exp Heamotol. 1990;18:237-73.

36. Qishen P, et al. Radioprotective effect of extract from Spirulina platensis in mouse bone marrow

cells studied by using the micronucleus test. Toxicology Let. 1989;48:165.

37. Horikoshi T, et al. Uptake of uranium by various cell fractions of Chlorella regularis.Radioisotopes, 1979 Aug;28(8):485-87.

38. Maisin J, et al. Yeast ribonucleic acid and its nucleotides as recovery factors in rats receiving anacute whole-body dose of X-rays.Nature, 1960;186:487-95.

39. Ebel JP, et al. Study on the therapeutic effect on irradiated mice of substances contained in RNApreparations.Int J Radiat Biol. 1969;16:201-09.

40. Wagner R, Silverman EC. Chemical protection against X-radiation in the Guinea-Pig. I.Radioprective action of RNA and ATP.Int J Radiat Biol. 1967;12:101-12.

41. Cousens G. Conscious Eating. North Atlantic Books; 2 edition (April 11, 2000). ISBN13:9781556432859

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Seaweeds & Kelp:


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Kitasato Arch Exp Med. 1992 Dec;65(4):209-16.

Suppression of 125I-uptake in mouse thyroid by seaweed feeding: possiblepreventative effect of dietary seaweed on internal radiation injury of the thyroid byradioactive iodine.

Maruyama H, Yamamoto I.

Department of Pathology, Kitasato University School of Hygienic Sciences, Kanagawa, Japan.

Abstract

We conducted an animal experiment to determine how dietary seaweeds rich in iodine and dietaryfibers suppress radioactive iodine uptake by the thyroid, using mice and four kinds of experimentaldiets, three with 1% or 2% powdered fronds of the kelp Laminaria religiosa and 2% powdered laverPorphyra yezoensis, and one with cellulose. Iodine content of a hot-water extract of the kelp was0.530 +/- 0.001%, and its dietary fiber (DF) values were 52.8 +/- 1.2%. Iodine in an extract of thelaver was 0.008 +/- 0.001%, and its DF values were 41.4% +/- 0.7%. A statistically significantreduction of 125I uptake by the thyroid, 3 hours after intragastric administration of theradionuclide at a dosage of 18.5 kBq or 185 kBq in 0.3 ml aqueous solution per mouse, was observedin mice previously fed the experimental diets containing 1% and 2% kelp during periods varyingfrom 24 hours to 7 days. The degree of the suppression was observed to depend on the amount ofiodine in the diet or in the injected sample, no matter whether organic or inorganic, judging fromthe results of an additional experiment. Thus, we conclude that previously fed iodine-richmaterial, especially dietary seaweeds rich in iodine and other minerals, vitamins, and

beta-carotene, such as kelps or laver supplemented with inorganic iodine, may beeffective in prevention of internal radiation injury of the thyroid. PMID: 1344008

Biomed Environ Sci. 1991 Sep;4(3):273-82.

Suppression of radioactive strontium absorption by sodium alginate in animals andhuman subjects.

Gong YF, Huang ZJ, Qiang MY, Lan FX, Bai GA, Mao YX, Ma XP, Zhang FG.

Institute of Radiation Medicine, Beijing, China.

Abstract

The effect of 23 sodium alginate preparations from different species of algae (Sargassum sp.) and

kelp (Laminaria sp.) on reducing the absorption of strontium was studied in detail. A pilotproduction procedure has been established. Na alginate from S. siliquastrum was proven to be apotent agent for reducing Sr absorption, with high efficiency and virtually no toxicity. It reduced thebody burden of strontium 3.3-4.2 fold in rats. Strontium absorption in human subjects was reducedby 78% (+/- 8.9) or completely suppressed the increase of serum Sr at 2 h after ingestion of stableSr in volunteers and decrease 24 h urine Sr to similar extent. No undesirable effects ongastrointestinal function was observed nor were Ca, Fe, Cu and Zn metabolism changed, both in theanimal experiments and in human. It was concluded that alginate preparations derivedfrom Sargassum species are a suitable antidote against radiostrontium absorption ona long-term basis, when added to bread at a 6% level. In cases of emergency, analginate syrup preparation appears to be more suitable because of its rapid action.


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PMID: 1764217

Studies Associated with NAC, Selenium, Vit. C & E, Lipoic acid and CoQ10 supplementation:

Radiat Res.2010 Apr;173(4):462-8.

Antioxidant diet supplementation starting 24 hours after exposure reduces radiationlethality.

Brown SL, Kolozsvary A, Liu J, Jenrow KA, Ryu S, Kim JH.

Henry Ford Hospital, Department of Radiation Oncology, Detroit, Michigan 48202, [email protected]

Abstract

Antioxidants mitigate radiation-induced lethality when started soon after radiation exposure, adelivery time that may not be practical due to difficulties in distribution and because the oraladministration of such agents may require a delay beyond the prodromal stage of the radiationsyndrome. We report the unexpected finding that antioxidant supplementation starting 24 h after

total-body irradiation resulted in better survival than antioxidant supplementation started soonafter the irradiation. The antioxidant dietary supplement was l-selenomethionine, sodiumascorbate, N-acetyl cysteine, alpha-lipoic acid, alpha-tocopherol succinate, and co-enzyme Q10. Total-body irradiation with 8 Gy in the absence of antioxidant supplementation was lethal by day 16.When antioxidant supplementation was started soon after irradiation, four of 14 mice survived. Incontrast, 14 of 18 mice receiving antioxidant supplementation starting 24 h after irradiation werealive and well 30 days later. The numbers of spleen colonies and blood cells were higher in micereceiving antioxidant supplementation starting 24 h after irradiation than in mice receivingradiation alone.A diet supplemented with antioxidants administered starting 24 h aftertotal-body irradiation improved bone marrow cell survival and mitigated lethality,

with a radiation protection factor of approximately 1.18.PMID: 20334518

Studies Associated with Calcium Intake (and therefore pertaining to Bone Meal supplementation):

Health Phys. 2004 Jun;86(6):557-64.

Dietary intakes of seven elements of importance in radiological protection by asianpopulation: comparison with ICRP data.

Iyengar GV, Kawamura H, Dang HS, Parr RM,Wang J,Akhter P, Cho SY, Natera E, Miah FK,Dojosubroto J, Nguyen MS.

Nutrition and Health-Related Environmental Studies Section Division of Human Health,International Atomic Energy Agency, Vienna, Austria. [email protected]

Abstract


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Within the framework of a Coordinated Research Project (CRP) organized by the InternationalAtomic Energy Agency, Vienna, the daily dietary intakes of seven elements by adult populationsliving in nine Asian countries were estimated. The countries that participated in the study wereBangladesh, China, India, Indonesia, Japan, Pakistan, Philippines, South Korea (Republic of Korea,ROK), and Vietnam and together they represented more than half of the world population. Theseven elements studied were calcium, cesium, iodine, potassium, strontium, thorium, and uranium.These elements have chemical and biological similarity to some of the radionuclides abundantlyencountered during nuclear power production and therefore data on these elements could provide

important information on their biokinetic behavior. Analyses of diet samples for these sevenelements were carried out using highly sensitive and reliable analytical techniques. One thousandone hundred and sixty analytical determinations were made on two hundred and twenty samples oftypical diets consumed in these countries to estimate the daily intakes of these elements by theadult Asian population. The median daily dietary intakes for the adult Asian population were foundto be 0.45 g calcium, 7 microg cesium, 90 microg iodine, 1.75 g potassium, 1.65 mg strontium, 1microg thorium, and 1 microg uranium. When compared with the intakes proposed for ICRPReference Man by International Commission for Radiological Protection, these intakes were lowerby factors of 0.41 for calcium, 0.7 for cesium, 0.45 for iodine, 0.53 for potassium, 0.87 for strontium,0.33 for thorium, and 0.52 for uranium. The lower daily intakes of calcium, cesium, and iodine byAsian population could be due to significantly lower consumption of milk and milk products, which

are rich in these elements. The significantly lower intake of calcium in most of the Asiancountries may lead to higher uptake of fission nuclide 90Sr and could result inperhaps higher internal radiation dose. The use of highly sensitive and reliable analyticalmethods resulted in accurate and lower intake values obtained for thorium and uranium, whichsuggest that radiation dose from their ingestion at natural background levels is likely to be lowerthan what may be concluded from ICRP data. PMID: 15167119

Health Phys. 2002 Jul;83(1):56-65.

Absorption of strontium from the gastrointestinal tract into plasma in healthy humanadults.

Apostoaei AI.

SENES, Oak Ridge, Inc, TN 37830, USA. [email protected]

Abstract

The radioactive isotopes of strontium have always been a major concern in radiation protection.Currently, radiostrontium is of interest for evaluation of the health effects of the Chernobyl accidentand for epidemiological studies in populations exposed to releases from the Mayak nuclear facilitiesin Russia. Ingestion is one of the most important exposure pathways involving radioactivestrontium. The main sources of published data on the fraction of the ingested strontium that istransferred to plasma (f1) are summarized. For some of these studies, the original data had to bereanalyzed and a new iterative method to account for the elimination in feces of strontium ofendogenous origin (i.e., that was absorbed to blood and has already been returned into feces) wasemployed. Data indicate no significant dependence of the absorbed fraction on sex or age at


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exposure within the adult group, but absorption of (radioactive) strontium is reduced ifthe intake of stable calcium is very high and is enhanced if the intake of calcium is verylow. The probability distribution function of f1 values is well represented by a lognormal curve witha geometric mean of 22.3% and a geometric standard deviation of 1.44 (95% confidence interval10.9% to 45.6%, or about a factor of 2 around the geometric mean). This distribution can beconsidered representative for the variability of the f1 values in a population of healthy adults. PMID:12075684

Melatonin:

Int J Radiat Oncol Biol Phys. 2004 Jul 1;59(3):639-53.

Melatonin as a radioprotective agent: a review.

Vijayalaxmi, Reiter RJ, Tan DX, Herman TS, Thomas CR Jr.

Department of Radiation Oncology, The University of Texas Health Science Center, San Antonio,78229, USA. [email protected]

Abstract

Melatonin (N-acetyl-5-methoxytryptamine), the chief secretory product of the pineal gland in thebrain, is well known for its functional versatility. In hundreds of investigations, melatonin has beendocumented as a direct free radical scavenger and an indirect antioxidant, as well as an importantimmunomodulatory agent. The radical scavenging ability of melatonin is believed to work viaelectron donation to detoxify a variety of reactive oxygen and nitrogen species, including the highlytoxic hydroxyl radical. It has long been recognized that the damaging effects of ionizing radiationare brought about by both direct and indirect mechanisms. The direct action produces disruption ofsensitive molecules in the cells, whereas the indirect effects ( approximately 70%) result from itsinteraction with water molecules, which results in the production of highly reactive free radicalssuch as *OH, *H, and e(aq)- and their subsequent action on subcellular structures. The hydroxylradical scavenging ability of melatonin was used as a rationale to determine its radioprotectiveefficiency. Indeed, the results from many in vitro and in vivo investigations have confirmed thatmelatonin protects mammalian cells from the toxic effects of ionizing radiation. Furthermore,several clinical reports indicate that melatonin administration, either alone or in combination withtraditional radiotherapy, results in a favorable efficacy:toxicity ratio during the treatment of humancancers. This article reviews the literature from laboratory investigations thatdocument the ability of melatonin to scavenge a variety of free radicals (including thehydroxyl radical induced by ionizing radiation) and summarizes the evidence thatshould be used to design larger translational research-based clinical trials usingmelatonin as a radioprotector and also in cancer radiotherapy. The potential use ofmelatonin for protecting individuals from radiation terrorism is also considered.PMID: 15183467 [PubMed - indexed for MEDLINE]

Morinda:

Zhong Xi Yi Jie He Za Zhi. 1991 Jul;11(7):415-7, 390.

[Comparison with the pharmacological actions of Morinda officinalis, Damnacanthusofficinarum and Schisandra propinqua].

[Article in Chinese]


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Qiao ZS, Wu H, Su ZW.

College of Pharmacy, Second Military Medical University, Shanghai.

Abstract

There are three kinds of plants,Morinda officinalis (1), Damnacanthus officinarum (2), andSchisandra propinqua (3) whose roots have been used since the ancient time. In this paper, some of

their pharmacological actions that are related to tonifying and invigorating Yang were examinedand compared. The body weight, the thymus weight, the amount of leukocyte in the blood, and thecontinuing swimming times of the young mice could be increased with the oral administration ofthe water extractions of (1) and (2) (P less than 0.05-0.001). The Rt of M-receptor in the brains ofthe hypothyroidism mice were decreased after administration of the water extracts of (1) and (2) (Pless than 0.05). (1) could also increased the amount of leukocyte in the blood of leukocytopenia micecaused by radiation of gamma-ray (P less than 0.01). (3) has not shown the obvious effects (Pgreater than 0.05).The results indicate that (1) and (2) have the ability of anti-fatigue,improving the immunological action of the young mice, and reducing the excitabilityof the para-sympathetic nervous system of the hypothyroidism mice throughdecreasing the Rt of M-receptor in their brains. All of them did not show acute

toxicity, inducing mutation, and sexual hormone like actions. PMID: 1914038

Aloe:

Georgian Med News. 2009 Jun;(171):80-3.

[Radio protective drug production from fresh leaves of Aloe arborescens Mill].

[Article in Russian]

Bakuridze AD, Nikolaev SM, Berashvili DT, Bakuridze KA, Tsomaia IV.

Abstract

Nowadays, phytogenous drugs are wildly used as radio protective substances.The aim of theresearch was to study radio protective characteristics of aloe juice fraction and todevelop new technology for radio protective drug production.Technological scheme forgetting the drug in two stages. The first stage - extraction of juice from fresh leaves; the second stage- extracting bagasse have been developed and optimal environment for bagasse extraction aredefined: Infusion of bagasse with 96 % ethyl spirit (1:1) during 30 minutes, continuation ofextracting with water on correlation to raw materials 10:1 at temperature of 70 degrees C during 30minutes. For the basis of the first series of balanced loading there are taken the optimal parametersof extracting process, on the basis of which in its turn was developed technological scheme of getting

dry extract of aloe. Dry extract is a fine-dispersed reddish-yellow (brownish-yellow) powder, whichcan be easily dissolved in warm (40-60 degrees C) water. Pharmacological researches wereconducted in the Institute of General and Experimental Biology, Siberian Branch, Russian.Academy of Sciences. The remarkable radio protective effect of the drug was revealed.PMID: 19578223

Structured Water:

J Photochem Photobiol B. 2010 Feb 12;98(2):144-51. Epub 2009 Dec 5.

Defensive effects of fullerene-C60/liposome complex against UVA-induced


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intracellular reactive oxygen species generation and cell death in human skinkeratinocytes HaCaT, associated with intracellular uptake and extracellular excretionof fullerene-C60.

Kato S, Kikuchi R, Aoshima H, Saitoh Y, Miwa N.

Laboratory of Cell-Death Control BioTechnology, Faculty of Life and Environmental Sciences,Prefectural University of Hiroshima, 562, Nanatsuka, Shobara, Hiroshima 727-0023, Japan.

Abstract

The UVA-irradiation of 10 J/cm(2) on HaCaT keratinocytes increased 59.1% of the intracellularreactive oxygen species (ROS) by NBT assay and the cell viability decreased to 31.5% by WST-1assay, comparing to the non-irradiated control. In the presence of fullerene-C60 (C60) incorporatedin phospholipid membrane vehicle (LiposomeFullerene: Lpsm-Flln) of 250-500 ppm, they wererestored to -9.1% to +2.3% of the ROS and 83.0-84.8% of the cell viability, but scarcely restored bythe liposome without C60 (Lpsm). In HaCaT cells administered with Lpsm-Flln (150 ppm), C60was ingested at the intracellular concentrations of 1.4-21.9 ppm for 4-24 h, and, intracellular C60was excreted by 80% at 4h after rinsing-out, and decreased to 2-10% after 24-48 h. C60 was

predominantly distributed around the outside of nuclear membrane without deterioration of intactcell morphology according to fluorescent immunostain. Thus Lpsm-Flln is found to be aneffective antioxidant that could preserve HaCaT keratinocytes against UVA-inducedcellular injury. Lpsm-Flln has a potential to serve as a cosmetic material for skinprotection against UVA. Copyright 2009 Elsevier B.V. All rights reserved.

PMID: 20060738 [PubMed - in process]

J Radiat Res (Tokyo). 2008 May;49(3):321-7. Epub 2008 Feb 16.

Fullerenol C60(OH)24 effects on antioxidative enzymes activity in irradiated humanerythroleukemia cell line.

Bogdanovi V, Stankov K, Icevi I, Zikic D, Nikoli A, Solaji S, Djordjevi A, Bogdanovi G.

Institute of Oncology, Department of Experimental Oncology, Sremska, Kamenica, Serbia.

Abstract

Radiotherapy-induced toxicity is a major dose-limiting factor in anti-cancer treatment. Ionizingradiation leads to the formation of reactive oxygen and nitrogen species (ROS/RNS) that areassociated with radiation-induced cell death. Investigations of biological effects of fullerenol haveprovided evidence for its ROS/RNS scavenger properties in vitro and radioprotective efficiency in

vivo. Therefore we were interested to evaluate its radioprotective properties in vitro in the humanerythroleukemia cell line. Pre-treatment of irradiated cells by fullerenol exerted statisticallysignificant effects on cell numbers and the response of antioxidative enzymes to X-ray irradiation-induced oxidative stress in cells. Our study provides evidence that the pre-treatment withfullerenol enhanced the enzymatic activity of superoxide dismutase and glutathioneperoxidase in irradiated K562 cells. PMID: 18285660 [PubMed - indexed for MEDLINE]

Sodium Bicarbonate (Baking Soda):

JEM.1917;25(5):693-719.


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A study of the acidosis, blood urea, and plasma chlorides in uranium nephritis in thedog, and of the protective action of sodium bicarbonate.

Goto K.

Abstract

Methods: The presence of an acidosis in dogs with experimental uranium nephritis is demonstrableby the Van Slyke-Stillman-Cullen method and that of Marriott. It is detected more readily by the

former method. This acidosis is associated with increase in the blood urea and plasma chlorides andwith the appearance of albumin and casts in the urine. Results: The oral administration of sodiumbicarbonate diminishes the acidosis, the increase in plasma chlorides, the amount of albumin andcasts in the urine, and, to a lesser degree, the increase in the blood urea following theadministration of uranium. It also diminishes the severity of the changes produced by uranium inthe kidneys. Conclusions: The oral administration of sodium bicarbonate to normaldogs raises the carbon dioxide content of the plasma as determined by the Van Slyke-Stillman-Cullen method, and reduces the nephrotoxicity associated with uraniumexposure in dogs.

J Radiol. 1994 Nov;75(11):571-5.

[Management of accidental internal exposure].

[Article in French]

Fatome M.

Abstract

Radionucleides can penetrate into the body via the lung, the digestive tract, wounds and sometimesthrough healthy skin. Once they have penetrated the body, they can either remain localized at thesite of entry or be rapidly metabolized. The risk is late effects. Radioelements must be eliminated as

rapidly as possible decreasing the exposure proportionally. The effectiveness of the treatmentdepends on early institution. Nevertheless, emergency intensive care or surgery may be required.As soon as possible, explorations must be carried out to evaluate the level of contamination (humanspectrometry, radiotoxicological examinations) and to start treatment. Modalities include non-specific techniques (lavage, insolubilization, laxatives) and specific techniques such ascomplexation or isotopic dilution (iodine for iodine, Prussian blue for cesium, DTPAfor plutonium, Diamox or sodium bicarbonate for uranium). Surgical cleaning of woundsand burns is an excellent means of decontamination. External contamination is often associated.Further contamination must be prevented immediately. PMID: 7844774

Int J Radiat Biol. 1995 Oct;68(4):389-93.

Efficacy of 3,4,3-LIHOPO for reducing the retention of uranium in rat after acuteadministration.


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Henge-Napoli MH,Archimbaud M,Ansoborlo E, Metivier H, Gourmelon P.

Institute de Protection et de Sret Nuclaire, IPSN, Fontenay aux Roses, France.

Abstract

Decorporation therapy is the only known effective method of reducing the radiation dose to personsfollowing accidental internal contamination with transportable radionuclides. Deposits of actinidesin bone should be minimized because development of osteosarcoma appears to be related tointernal exposure. In contrast with other actinides, such as plutonium or americium wherechelating agent treatment is efficient, the therapeuric approaches used for cases of uraniumcontamination are widely ineffective. This is the first report on in vivo efficacy of a chelating agent,a siderophore analogue code named 3,4,3-LIHOPO, after systematic exposure to natural uranium inthe rat. Using the classical antidotal therapy (sodium bicarbonate) for comparison, this ligand hasbeen investigated for its ability to remove uranium from rats after intravenous or intramuscularinjection as nitrate. Following an immediate single intramuscular or intravenous injection of 3,4,3-LIHOPO (30 mumol.kg-1) urinary excretion of uranium was greatly enhanced with a corresponding

reduction 24 h later in kidney and bone uranium content (to about 20 and 50% of the control ratrespectively). Under identical experimental conditions, sodium bicarbonate (640mumol.kg-1) reduced the uranium content in kidney in kidney and bone only to about90 and 70% of controls respectively, and there was less enhancement of uraniumexcretion. However, when treatment was delayed by 30 min and administeredintraperitoneally, there was no marked difference in retention and excretion ofuranium between the two compounds. As this ligand showed no apparent irreversible toxicityat effective dosages, it is concluded that the administration of the 3,4,3-LIHOPO chelating agentrepresents potentially a most significant advance for prompt treatment of uranium contamination,while a more detailed investigation is necessary on the possible advantage when treatment delayed.PMID: 7594963

Ann Pharm Fr. 1999 Sep;57(5):397-400.

[Reduction of renal uranium uptake by acetazolamide: the importance of urinaryelimination of bicarbonate].

[Article in French]

Destombes C, Laroche P, Cazoulat A, Grasimo P.

Centre d'Etudes du Bouchet, Clamart.

Abstract

Acetazolamide was compared with bicarbonate for the treatment of contamination with uranium.Uranium was injected peritoneally in rats, and its distribution was investigated. Acetazolamide wasthree times more efficient than bicarbonate in reducing the renal content of uranium. On the other


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hand, it had no effect on hepatic or skeletal content. In this study, renal physiology provides thebasis for understanding the mode of action of acetazolamide and bicarbonate. In this context, it isof interest to determine the alkalinity of the urine, with the aim of knowing whether

bicarbonate is present to mobilize uranium. PMID: 10520511

J Cell Physiol. 2005 Dec;205(3):428-36.

Alkaline induces metallothionein gene expression and potentiates cell proliferation inChinese hamster ovary cells.

Lin KA, Chen JH, Lee DF, Lin LY.

Institute of Radiation Biology and Department of Life Science, National Tsing Hua University,Hsinchu, Taiwan.

Abstract

Metallothionein (MT) gene expression is increased in cadmium resistant Chinese hamster ovarycells (CHO Cd(R)) upon medium (regular or serum-free) change during culturing. Among themajor components of the medium, NaHCO3 was found to be able to induce MT geneexpression in a dose- and time-dependent manner. The same effect was observed with otheralkaline solutions, such as HEPES and NaOH. Using MT promoter-luciferase reporter geneconstructs, we found that the presence of metal response elements (MREs) in the promoter region isnecessary for NaHCO3-induced MT gene transcription. This finding is further supported by theobservation that the binding activity between the metal-responsive transcription factor 1 (MTF-1)

and the MRE were increased after NaHCO3 treatment. Following NaHCO3 treatment, an increasein cell proliferation was observed in CdR cells but not in the parental CHO K1 cells that do notexpress MT transcripts due to MT gene methylation. Using synchronized cells, an increase in cellproliferation was observed 9 h after NaHCO3 addition. Notably, proliferation of CHO K1 cells wasincreased when transfected with an MT gene. The effect of MT on cell growth was affirmed bytreating CHO K1 cells with 5-azacytidine (Aza) to demethylate the MT gene. Proliferation increasedin Aza-treated CHO K1 cells after NaHCO3 treatment. These results demonstrate that NaHCO3stimulates MT gene expression and causes an enhancement of cell proliferation in CHO cells. (c)2005 Wiley-Liss, Inc. PMID: 15965962

Toxicol Appl Pharmacol. 2006 Jun 15;213(3):245-55. Epub 2006 Jan 4.

Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-induciblefactor-1 alpha (HIF-1alpha) and HIF-regulated genes.

Li Q, Chen H, Huang X, Costa M.

Nelson Institute of Environmental Medicine, New York University, School of Medicine, 57 Old Forge


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Road, NY 10987, USA.

Abstract

Several metal ions that are carcinogenic affect cellular iron homeostasis by competing with irontransporters or iron-regulated enzymes. Some metal ions can mimic a hypoxia response in cells

under normal oxygen tension, and induce expression of HIF-1alpha-regulated genes. This studyinvestigated whether 12 metal ions altered iron homeostasis in human lung carcinoma A549 cells asmeasured by an activation of IRP-1 and ferritin level. We also studied hypoxia signaling bymeasuring HIF-1alpha protein levels, hypoxia response element (HRE)-driven luciferase reporteractivity, and Cap43 protein level (an HIF-1alpha responsive gene). Our results show the following:(i) Ni(II), Co(II), V(V), Mn(II), and to a lesser extent As(III) and Cu(II) activated the binding ofIRP-1 to IRE after 24 h, while the other metal ions had no effect; (ii) 10 of 12 metal ions inducedHIF-1alpha protein but to strikingly different degrees. Two of these metal ions, Al(III) and Cd(II),did not induce HIF-1alpha protein; however, as indicated below, only Ni(II), Co (II), and to lesserextent Mn(II) and V(V) activated HIF-1alpha-dependent transcription. The combined effects ofboth [Ni(II) + As(III)] and [Ni(II) + Cr(VI)] on HIF-1alpha protein were synergistic; (iii) Addition

of Fe(II) with Ni(II), Co(II), and Cr(VI) attenuated the induction of HIF-1alpha after 4 htreatment; (iv) Ni(II), Co(II), and Mn(II) significantly decrease ferritin level after 24 h exposure;(v) Ni(II), Co(II), V(V), and Mn(II) activated HRE reporter gene after 20 h treatment; (vi) Ni(II),Co(II), V(V), and Mn(II) increased the HIF-1-dependent Cap43 protein level after 24 h treatment.In conclusion, only Ni (II), Co (II), and to a lesser extent Mn(II) and V(V) significantly stabilizedHIF-1alpha protein, activated IRP, decreased the levels of ferritin, induced the transcription of HIF-dependent reporter, and increased the expression of Cap43 protein levels (HIF-dependent gene).The mechanism for the significant stabilization and elevation of HIF-1alpha protein which drivesthese other parameters was previously shown by us and others to involve a loss of cellular Fe as wellas inhibition of HIF-1alpha-dependent prolyl hydroxylases which target the binding of VHLubiquitin ligase and degrade HIF-1alpha. Even though there were small effects of some of the other

metals on IRP and HIF-1alpha, downstream effects of HIF-1alpha activation and therefore robusthypoxia signaling were only observed with Ni(II), Co(II), and to much lesser extents with Mn(II)and V(V) in human A549 lung cells. It is of interest that the metal ions that were mosteffective in activating hypoxia signaling were the ones that were poor inducers ofmetallothionein protein and also decreased Ferritin levels, since both of theseproteins can bind metal ions and protect the cell against toxicity in human lung cells. Itis important to study effects of these metals in human lung cells since this represents a major routeof human environmental and occupational exposure to these metal ions. PMID: 16386771

***********************************************************************

Precautionary Measures for Possible RadiationPlumeBy The School of Natural Healing


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In answer to the many inquiries of what to do about the recent news and reports (New York Times)of a radiation plume reaching the west coast by Friday, here are some things to know and ways inwhich you can be prepared.

At this point the levels of radiation prospected to be in the plume that would actually fall onestimated California, Oregon, Washington, British Columbia, Alaska, etc. is very minimal and is not

to pose a serious risk to health. However, "if" the situation in Japan worsens (ie. the Fukushimareactors have a rod "meltdown" - creating a massive release of radiation into the atmosphere) takingthe following precautions/preparations would be our suggestion, especially for those living in thepacific and on the west coast.

1) Take the time to reevaluate your emergency plan and supplies as a family. Make sure yourvehicles are not empty of fuel in case you need to evacuate and do not count on phones working incase of actual emergency.

2) If suggestion is and you plan to, stay put and to stay within your home for an allotment of timemake sure you have plastic and duct tape to seal your windows and doors as well as the supplies

needed in the case of a usual emergency: water, food, etc.

3) If you plan to evacuate, have at least a 72-hour kit ready to go at a moment's notice. This is goodto have no matter what you plans are.

4) Staring now, significantly increase your intake of naturally sourced iodine-containing foods andsuperfoods: (*estimated amounts of naturally occurring iodine)

Icelandic Kelp - *8000ppmKelp, Dulse, etc. (Seaweeds) - *5400ppmChlorella - *100ppmSpirulina - *70ppmPistacios - *51ppmDark Greens in all there varietyColorful vegetables & fresh fruitsOnions & Garlic

5) The purpose of increasing your intake of iodine-containing foods is to raise the amount of stableiodine in the blood. This will increase the likelihood that the thyroid will absorb the stable iodineinstead of the radioactive iodine (iodine-129 and iodine-131) released during a nuclear accident.

6) During the intake of iodine (kelp capsules SNH recommendation: 8-12 capsules a day dependingon the size and health of the individual) further precautionary measures would be to take the four

Dr. Christopher's Cleansing Formulas to keep things cleaned out (Lower Bowel Formula, KidneyFormula, Liver & Gall Bladder Formula, and the Blood Stream Formula) and then to add the HeavyMineral Bugleweed Formula for additional cleansing.

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