rapid p b s p r (spr) d using comsol & m s · "rapid prototyping" of biosensing...

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"RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES USING COMSOL & MATLAB SOFTWARE Presented by Dominic Carrier Presented at the COMSOL Conference 2009 Boston

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Page 1: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

"RAPID PROTOTYPING" OF BIOSENSING SURFACE

PLASMON RESONANCE (SPR) DEVICES

USING COMSOL & MATLAB SOFTWARE

Presented byDominic Carrier

Presented at the COMSOL Conference 2009 Boston

Page 2: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

• Introductiono Why do we need biosensing?o What is biosensing?o How we do it (with SPR)?

• Setup

• Results

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Page 3: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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INTRO - WHY

Page 4: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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Distance

Inte

nsity

INTRO - WHAT

Page 5: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

Negative real dielectric constant allows propagating evanescent surface wave (a.k.a. Surface plasmons)

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INTRO - HOW

Dielectric

Metallic Layer

Page 6: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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INTRO - HOW

Page 7: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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WHY

Page 8: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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A B

Incident Light

INTRO - SP 101

Page 9: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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A B A+B

Symmetry Axis

PMLLight Source

Sensing AreaIncident Light Modulated

Surface Plasmon

SETUP

Page 10: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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Symmetry Axis

PMLLight Source

SETUP

Model Specs:• RF Module : 2D in-plane “Harmonic propagation”• Typically 20 to 50 um long• 10 to 20 node elements per wavelength (total ~250 000 elements)

Page 11: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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RESULTS - PART 1

Page 12: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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|Hz|

At Anti-ResonanceAt Resonance

RESULTS - PART 2

Page 13: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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RESULTS - PART 3

Page 14: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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• Successfully achieved reproduction of SPR with Comsol

• Using “rapid-prototyping”, creation of diverse geometry was easy

• Modulation of output signal is observed

• The SP grating cavity is a promising scheme for Biosensing

Page 15: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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Prof. Jan J. Dubowski

Page 16: RAPID P B S P R (SPR) D USING COMSOL & M S · "RAPID PROTOTYPING" OF BIOSENSING SURFACE PLASMON RESONANCE (SPR) DEVICES. USING. COMSOL & M. ATLAB. S. OFTWARE. Presented by. Dominic

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Thank you