recent advances in neonatal medicine

FINAL PROGRAM

RECENT ADVANCES IN NEONATAL MEDICINE

thIX INTERNATIONAL SYMPOSIUM

HONORINGPROF. RICHARD B. JOHNSTON, MD, DENVER

WÜRZBURG, GERMANY OCTOBER 1 - 3, 2021

SCIENTIFIC ORGANIZATIONPROF. CHRISTIAN P. SPEER, MD, FRCPE

CONTENT

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Page

Welcome 4

Time Table 5

Faculty 7

Workshops 10

Symposium 16

Poster Sessions 25

Past Symposia 35

City Map of Würzburg 36

General Information 37

Sponsors 39

WELCOME

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Dear colleagues, dear ladies and gentlemen,

It is a great pleasure to welcome you to the IXth International Symposium

RECENT ADVANCES IN NEONATAL MEDICINE which is dedicated to my

admired academic mentor Prof. Richard B. Johnston Jr., MD, Denver,

USA. His basic research focused on the development of innate immunity

and host defense mechanisms; as Medical Director of “March of Dimes”

he was instrumental in reducing birth defects with folic acid, and,

moreover, he established a huge program into the causes of preterm

labor.

RECENT ADVANCES IN NEONATAL MEDICINE was originally scheduled

for April 2020, however, due to the SARS-CoV2 pandemic we had to

postpone the IXth edition to October 2021. The unique feature of

RECENT ADVANCES IN NEONATAL MEDICINE 2021 is that all faculty

members and delegates will be fully immunized by October 2021 and, in

addition, a hygiene concept will be provided in the conference center

which will include all safety measures of disease protection.

Unfortunately, however, delegates from some countries may not be able to

attend this year's symposium due to the current epidemiological situation

of SARS-COV 2 in their country or ongoing travel restrictions. For these

colleagues we offer an “on demand” registration which will give them

access to the symposium's presentations and panel discussions for 3

months.

I would like to thank all faculty members for their great personal support

and, moreover, to express my sincere gratitude to the generous sponsors

of RECENT ADVANCES IN NEONATAL MEDICINE; without their essential

help it would have been impossible to invite such a prominent faculty, to

offer reduced registration fees for delegates from low- and middle-income

countries and to realize this ambitious project.

Despite all limitations I wish all of you a rewarding and memorable

RECENT ADVANCES IN NEONATAL MEDICINE which will celebrate it's

25th anniversary in 2021.

Christian P. Speer

Würzburg, September 15, 2021

TIME TABLE

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Poster Poster

Satellite Symposium

Opening WS I

Cardiopulmonary Transition, Postnatal

Stabilization and Emergencies

WS II

RDS and Surfactant

WS IV

BPD:From Bench to

Bedside

WS VII

Strategies for a Successful

Feeding

WS III

Optimal Ventilatory Strategies

WS VIII

Pain, Seizures and ROP

WS VI

The Neonatal Immune

System and Immuno-

deficencies

WS V

Intrauterine Inflammation and

Infection

The First Minutesof Life

RespiratoryCare

in 2021

BPD andRespiratory Outcome

Growth Failureand

Optimal Nutrition

Brain Injuryand

Pain Perception

Hidden Risksfor Retinal and

Cerebral Damage;Neurodevelopmental

Outcome

Poster Prize

Microbiome, Platelets andStem Cells

Drugs and OtherInterventions

Concluding Remarks

Workshops Symposium Symposium

0018

0008

Time

FRIDAYOCTOBER 1, 2021

SATURDAYOCTOBER 2, 2021

SUNDAYOCTOBER 3, 2021

Seminars A - C

Seminars D - F

Lunch Seminar

Hardcover / ISBN-13: 978-0198854807,ISBN-10: 01988548039780198854807 / July 2021 / 432 pages

FACULTY

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Prof. Sture Andersson, MD, PhDDepartment of NeonatologyUniversity of HelsinkiHelsinki, Finland

Prof. John N. van den Anker, MD, PhD Children's National Medical CenterWashington, DC, USA

Prof. Eduardo Bancalari, MDDivision of NeonatologyJackson Memorial Medical CenterMiami, USA

Prof. Eugenio Baraldi, MDWomen's and Children's Health DepartmentUniversity of PadovaPadova, Italy

Prof. Christoph Bührer, MDDepartment of NeonatologyCharité University Medical CenterBerlin, Germany

Prof. Robert Carr, MDDepartment of HaematologySt. Thomas HospitalLondon, UK

Prof. Tore Curstedt, MD, PhDKarolinska University LaboratoryKarolinska University HospitalStockholm, Sweden

Prof. Gabriel Dimitriou, MD, PhDPaediatric Department NICUUniversity General Hospital of PatrasPatras, Greece

Prof. A. David Edwards, MA, DSc, FRCPCenter for Developing BrainKing's College LondonLondon, UK

Kirsten Glaser, MDUniversity Children's Hospital University of LeipzigLeipzig, Germany

Rangmar Goelz, MDDepartment of NeonatologyUniversity Hospital TübingenTübingen, Germany

Prof. Johannes B. van Goudoever, MDEmma Children's HospitalAmsterdam UMCAmsterdam, The Netherlands

Prof. Joseph Haddad, MDNeonatal and Pediatric Intensive CareSaint George University HospitalBeirut, Lebanon

Prof. Henry L. Halliday, MD, FRCP, FRCPERoyal Maternity HospitalBelfast, Northern Ireland

Prof. Mikko Hallman, MD, PhDDepartment of PediatricsUniversity of OuluOulu, Finland

Prof. Thor W.R. Hansen, MD, PhD, FAAPInstitute for Clinical MedicineUniversity of OsloOslo, Norway

Prof. Christoph Härtel, MDUniversity Children's HospitalUniversity of WürzburgWürzburg, Germany

Prof. Dominique Haumont, MDNeonatal UnitSaint-Pierre University HospitalBrussels, Belgium

Prof. William W. Hay, Jr., MDChildren's Hospital ColoradoUniversity of Colorado School of MedicineDenver, USA

Prof. Ann Hellström, MD, PhD The Queen Silvia Children´s HospitalSahlgrenska Academy Göteborg, Sweden

Prof. Iman F. Iskander Boulos, MDDepartment of Pediatrics Cairo University Cairo, Egypt

Prof. Boris W. Kramer, MD, PhDMaastricht University Medical CenterMaastricht, The Netherlands

Prof. Arunas Liubsys, MDNeonatal CenterVilnius UniversityVilnius, Lithuania

Prof. Neil Marlow, MD, FRCP, FRCPCHFaculty of Population Health SciencesUniversity College LondonLondon, UK

FACULTY

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Prof. Linda J. Van Marter, MD, MPHDepartment of PediatricsBrigham and Women's HospitalBoston, USA

Prof. Richard J. Martin, MDNeonatal ResearchRainbow Babies & Children's HospitalCleveland, USA

Prof. Neena Modi, MD, FRCP, FRCPEImperial College LondonChelsea and Westminster Hospital CampusLondon, UK

Henner Morbach, MDUniversity Children's HospitalUniversity of WürzburgWürzburg, Germany

Prof. Rory E. Morty, MDDepartment of Translational PulmonologyHeidelberg University HospitalHeidelberg, Germany

Prof. Won Soon Park, MD, PhDSamsung Medical CenterSungkyunkwan UniversitySeoul, Korea

Prof. Arjan B. te Pas, MDDepartment of PediatricsLeiden University Medical CentreLeiden, The Netherlands

Prof. Natella Rakhmanina, MD, PhDHIV Services & Special ImmunologyThe George Washington UniversityWashington D.C., USA

Prof. Peter Rimensberger, MDDepartment of PediatricsUniversity Hospital of GenevaGeneva, Switzerland

Prof. Charles Christoph Roehr, MDNational Perinatal Epidemiology Unit University of OxfordSouthmead Hospital, University of BristolOxford / Bristol, UK

Prof. Ola D. Saugstad, MD, PhD, FRCPEDepartment of Pediatric ResearchThe National HospitalOslo, Norway

Prof. Eric S. Shinwell, MDNeonatologyBar-Ilan UniversityTsfat, Israel

Prof. Dominique Singer, MDCenter for Obstetrics and PediatricsUniversity Medical Center EppendorfHamburg, Germany

Prof. Rebecca Slater, MDDepartment of PaediatricsUniversity of Oxford,Oxford, UK

Prof. José Maria Solano, MCNeonatal Intensive Care UnitClinica Materno-Infantil ColsubsidioBogotá, Colombia

Prof. Christian P. Speer, MD, FRCPEUniversity Childen's HospitalUniverstity of Würzburg Würzburg, Germany

David G. Sweet, MDRegional Neonatal UnitRoyal Maternity HospitalBelfast, Northern Ireland

Prof. Bernard Thébaud, MD, PhDDepartment of Pediatrics University of OttawaOttawa, Canada

Prof. Henrik A. Verder, MDDepartment of PediatricsHolbaek HospitalHolbaek, Denmark

Prof. Linda S. de Vries, MD, PhDDepartment of PediatricsWilhelmina Children's HospitalUtrechts, The Netherlands

Prof. Clyde Wright, MDPerinatal Research CenterUniversity of Colorado School of MedicineDenver, USA

WORKSHOPS

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FRIDAY, OCTOBER 1, 2021

Workshop ICARDIOPULMONARY TRANSITION, POSTNATAL STABILIZATION AND EMERGENCIES

Chair: O.D. Saugstad, Oslo, Norway; D. Singer, Hamburg, Germany

158 Monitoring stabilization/resuscitation at birth A.B. te Pas, Leiden, The Netherlands

� Neonatal resuscitation guidelines: Scientific rationale and evidence� O.D. Saugstad, Oslo, Norway

� Reversing the irreversible? Interactions between hypoxia and hypothermia in the perinatal period� D. Singer, Hamburg, Germany

45 9 INTERACTIVE DISCUSSION

1510 COFFEE BREAK

Workshop IIRDS AND SURFACTANT

Chair: G. Dimitriou, Patras, Greece; H. Verder, Holbaek, Denmark

4510 A stepwise therapeutic approach to RDS P. Rimensberger, Geneva, Switzerland

� Disease specific strategies of neonatal ventilation� G. Dimitriou, Patras, Greece

� European guidelines for the management of RDS� D.G. Sweet, Belfast, Northern Ireland


12 LUNCH BREAK45

0013 POSTER SESSION I - II

WORKSHOPS

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FRIDAY, OCTOBER 1, 2021

Workshop IIIOPTIMAL VENTILATORY STRATEGIES

Chair: C. Bührer, Berlin, Germany; C. Wright, Denver, USA

0014 Ventilatory strategies to prevent lung injury E. Bancalari, Miami, USA

� iNo for preterm infants: Evidence versus practice� B. Thébaud, Ottawa, Canada

� HFOV in neonates: Still relevant in 2020?� P. Rimensberger, Geneva, Switzerland


0016 COFFEE BREAK

Workshop IVBPD: FROM BENCH TO BEDSIDE

Chair: S. Andersson, Helsinki, Finland; K. Glaser, Leipzig, Germany

3016 Experimental models of BPD R.E. Morty, Heidelberg, Germany

Pulmonary hypertension and BPD L.J. van Marter, Boston, USA Present and future of BPD E. Baraldi, Padova, Italy


3018 � Parallel Seminars

� A How to get your manuscript rejected? E.S. Shinwell, Tsfat, Israel

� B How to design a clinical trial: From basics to pitfalls N. Modi, London, UK

C Neonatal clinical pharmacology: A delicate combination of developmental biology and genetics J.N. van den Anker, Washington D.C., USA

WORKSHOPS

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Workshop VINTRAUTERINE INFLAMMATION AND INFECTION

Chair: S. Andersson, Helsinki, Finland; W.S. Park, Seoul, Korea

158 Intrauterine inflammation and possible consequences for the preterm infant B.W. Kramer, Maastricht, The Netherlands

Ureaplasma species: The hidden danger for preterm infants K. Glaser, Leipzig, Germany

Postnatal CMV-infection in very premature infants: Does it matter? R. Goelz, Tübingen


1510 COFFEE BREAK

Workshop VITHE NEONATAL IMMUNE SYSTEM AND IMMUNODEFICIENCIES

Chair: B.W. Kramer, Maastricht, The Netherlands; B. Thébaud, Ottawa, Canada

4510 Modulation of the immune-microbiome interplay - any benefit for the newborn? C. Härtel, Würzburg, Germany

When mother’s antibodies attack the neonate C. Bührer, Berlin, Germany

Rare but dangerous: Immunodeficiencies of the newborn H. Morbach, Würzburg, Germany


4512 LUNCH BREAK

0013 POSTER SESSION I - II

FRIDAY, OCTOBER 1, 2021 (Parallel Sessions)

WORKSHOPS

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Workshop VIISTRATEGIES FOR A SUCCESSFUL FEEDING

Chair: W.W. Hay Jr., Denver, USA; I. Iskander, Cairo, Egypt

0014 Parenteral nutrition for immature preterm infants in the first week of life and beyond: Fluid intake, electrolytes and energy supply W.W. Hay Jr., Denver, USA

Do we need fortifiers and nutritional supplements for preterm infants? N. Modi, London, UK

Strategies for a successful feeding of the premature baby A. Liubsys, Vilnius, Lithuania


0016 COFFEE BREAK

Workshop VIIIPAIN, SEIZURES AND ROP

Chair: N. Marlow, London, UK; J.M. Solano, Bogota, Colombia

3016 Is there a way to measure pain perception in preterm infants? R. Slater, Oxford, UK

The role of aEEg in seizure identification and prediction of outcome L.S. de Vries, Utrecht, The Netherlands

Growth factors and Anti-VEGF in severe ROP: Has the time come? A. Hellström, Gothenburg, Sweden


3018

A How to get your manuscript rejected? E.S. Shinwell, Tsfat, Israel

� B How to design a clinical trial: From basics to pitfalls N. Modi, London, UK

C Neonatal clinical pharmacology: A delicate combination of developmental biology and genetics J.N. van den Anker, Washington D.C., USA

FRIDAY, OCTOBER 1, 2021 (Parallel Sessions)

Parallel Seminars

SYMPOSIUM

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SATURDAY, OCTOBER 2, 2021

158 Opening and Welcome C. P. Speer, Würzburg, Germany

THE FIRST MINUTES OF LIFEChair: S. Andersson, Helsinki, Finland; R. Martin, Cleveland, USA

258 Cardiopulmonary transition at birth: Optimal strategies for support and stabilization A. B. te Pas, Leiden, The Netherlands

8 Neonatal oxygen exposure and optimal oxygen saturations:45

Do we have the answer yet? O.D. Saugstad, Oslo, Norway

059 PANEL DISCUSSION

9 Laudatio for Prof. Richard B. Johnston Jr., Denver, USA30

C. P. Speer, Würzburg, Germany

Chiesi Prize for Excellence in NeonatologyO.D. Saugstad, Oslo, Norway

0010 COFFEE BREAK

RESPIRATORY CARE IN 2021Chair: G. Dimitriou, Patras, Greece; D.G. Sweet, Belfast, Northern Ireland

3010 Non-invasive respiratory support of preterm infants with RDS C. Wright, Denver, USA

50 10 Limitations of non-invasive ventilation: When is mechanical ventilation in the very immature infant indicated? E. Bancalari, Miami

10 11 Minimally invasive surfactant therapy: Useful or fashionable? C. Härtel, Würzburg, Germany

30 11 CPAP failure, LISA and mechanical ventilation C.C. Roehr, Oxford/Bristol, UK


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3012 LUNCH BREAK

0013

30 13 NNI SYMPOSIUM: UPDATE ON NEONATAL NUTRITION The role of human milk oligosaccharides (HMOs) in early infant nutrition N. Sprenger, Lausanne, Switzerland

Individualized nutrition in preterms – quo vadis? N. Haiden, Vienna, Austria

BPD AND RESPIRATORY OUTCOMEChair: M. Hallman, Oulu, Finland; L.J. van Marter, Boston, USA

0014 BPD from pathogenesis to prevention: An unresolved problem E. Bancalari, Miami, USA

2014 Topical steroids: Inhaled or mixed with surfactant? E. Shinwell, Tsfat, Israel

4014 Why do former preterm infants wheeze? R.J. Martin, Cleveland, USA

0015 Follow-up and long term respiratory function following prematurity E. Baraldi, Padua, Italy


4515 COFFEE BREAK

MICROBIOME, PLATELETS AND STEM CELLSChair: C. Härtel, Würzburg, Germany; W.S. Park, Seoul, Korea

1516 NEC, sepsis and gut microbiome – more than gut feelings? B.W. Kramer, Maastricht, The Netherlands

3516 Platelet transfusion: More harm than benefit? R. Carr, London, UK

5516 Stem cells: The magic cure for BPD and brain damage? B. Thébaud, Ottawa, Canada


POSTER SESSION III - IV

SYMPOSIUM


SYMPOSIUM

PARALLEL SEMINARS

4517 D Antibiotics for the newborn baby: Friends or foes? A. Liubsys, Vilnius, Lithuania E Challenges in neonatal care in resource poor settings J. Haddad, Beirut, Lebanon

F Pharmacological prevention and treatment of maternal and neonatal HIV infection N. Rakhmanina, Washington, D.C., USA

SYMPOSIUM


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Parallel Seminars

BRAIN INJURY AND PAIN PERCEPTIONChair: T.W.R. Hansen, Oslo, Norway; N. Marlow, London, UK

008 Special Lecture How can we reduce brain injury in preterm infants? A.D. Edwards, London, UK

308 Monitoring the neonatal brain: How, when and for how long? L.S. de Vries, Utrecht, The Netherlands

508 Analgetic drugs: Impact on pain perception and brain activity R. Slater, Oxford, UK

109 The use of opioids in the NICU: Navigating between Scylla and Charybdis J.N. van den Anker, Washington D.C., USA


0010 COFFEE BREAK

3010

Announcement of the Awardees T. Curstedt, Stockholm, Sweden

HIDDEN RISKS FOR RETINAL AND CEREBRAL DAMAGE; NEURODEVELOPMENTAL OUTCOME Chair: A.D. Edwards, London, UK; C. Bührer, Berlin, Germany

4510 Preventive strategies and up-to-date treatment of severe ROP A. Hellström, Gothenburg, Sweden

0511 Hypoxic-ischemic episodes: A hidden risk for brain damage of very immature preterm infants? R.J. Martin, Cleveland, USA

25 11 Neonatal jaundice: A puzzle still unresolved T.W.R. Hansen, Oslo, Norway

45 11 Outcomes into adulthood for our most immature infants N. Marlow, London, UK


SYMPOSIUM

SUNDAY, OCTOBER 3, 2021

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Poster Prize

30 12 LUNCH BREAK

45 12 Lunch Seminar

Partial Personhood: The Newborn in History M. Obladen, Berlin, Germany

GROWTH FAILURE AND OPTIMAL NUTRITIONChair: S. Andersson, Helsinki, Finland; D. Haumont, Brussels, Belgium

3013 Preterm nutrition in 2020 - breast milk, probiotics & co: Myths and facts N. Modi, London

5013 Essentials and pitfalls of parenteral nutrition J. van Goudoever, Amsterdam, The Netherlands

1014 How to manage postnatal growth failure? W.W. Hay Jr., Denver, USA


0015 COFFEE BREAK

DRUGS AND OTHER INTERVENTIONSChair: M. Hallman, Oulu, Finland; C. Wright, Denver, USA

3015 Pre- and postnatal steroids: A critical appraisal E.S. Shinwell, Tsfat, Israel

5515 Caffeine in preterm infants: where are we in 2021? C.C. Roehr, Oxford/Bristol, UK


4516 CONCLUDING REMARKS C. P. Speer, Würzburg, Germany

SYMPOSIUM

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SUNDAY, OCTOBER 3, 2021

00Friday, October 1, 2021, 13 hrs

I RESPIRATORY CARE, PULMONARY DISEASES AND BPD Chair: G. Dimitriou, Patras, Greece; J.M. Solano, Bogota, Colombia

1THE COMPARISON OF TWO DIFFERENT WEANING METHODS FOR CONTINUOUS POSITIVE AIRWAY PRESSURE I. Šliaužienė, R. Brinkis, I. Aldakauskienė, A. Pužas, D. Stonienė, R. Tamelienė Department of Neonatology, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania

2RESPIRATORY FAILURE IN A PRETERM NEONATE WITH A COMBINATION OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE MUTATIONS: A CASE REPORTM. Tsirigotaki, E. Saitakis, A. Kleisarchaki, V. Kotsira, P. Skoula, E. Hatzidaki Department of Neonatology & Neonatal Intensive Care Unit, University Hospital of Heraklion, Crete, Greece

3ACCURACY OF TRANSCUTANEOUS BLOOD GAS MEASUREMENT IN CRITICALLY ILL NEONATES

1,2 3 1 1,2,4P. Baumann , V. Gotta , S. Adzikah , V. Bernet1 2University Children`s Hospital; Children's Research Centre, University Children's

3Hospital Zurich, Zurich; Department of Pediatric Pharmacology and Pharmacometrics, 4University of Basel Children's Hospital, Basel; current affiliation: Department of

Neonatology, Hospital Zollikerberg, Switzerland

4DD-SURF: SURFACTANT ADMINISTRATION IN BETWEEN INSURE AND LISAL. Mense, B. Seipolt, M. Rüdiger University Hospital Carl Gustav Carus, Department of Pediatrics, Division of Neonatology & Pediatric Intensive Care, Dresden, Germany

5PREDICTION OF BRONCHOPULMONARY DYSPLASIA AT BIRTH BY MACHINE LEARNING ANALYSIS OF CLINICAL AND DIGITAL SPECTRAL DATA

1 2 3 1 1 1H. Verder , C. Heiring , R. Ramanathan , N. Scoutaris , P. Schousboe , P. Verder , T.E. 4 5 6 1 7 8Jessen , L. Bender , M. Dahl , C. Eschen , J. Fenger-Grøn , J. Reinholdt , H.

9 1Smedegaard , A. Höskuldsson1 4Department of Pediatrics, Department of Clinical Biochemistry, Holbaek University

2 8Hospital, Holbaek, Denmark; Department of Neonatology, Rigshospitalet; Department of 9Pediatrics, Herlev Hospital; Department of Pediatrics, Hvidovre Hospital, University of

3Copenhagen, Copenhagen, Denmark; Divison of Neonatal Medicine, LAC+USC Medical 5Center, Los Angeles, USA; Department of Pediatrics, Aalborg Hospital, University of

6 7Aalborg, Aalborg, Denmark; Department of Pediatrics, Odense Hospital; Department of Pediatrics, Kolding Hospital, University of Southern Denmark, Denmark

POSTER SESSION I - II

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II - NUTRITION / GROWTH / NEURODEVELOPMENTAL OUTCOME Chair: H. van Goudoever, Amsterdam, Netherlands; W.W. Hay Jr., Denver, USA

6CHANGES IN HUMAN MILK MACRONUTRIENT, LYSOZYME AND LACTOFERRIN COMPOSITION DURING MILK PROCESSING IN VILNIUS DONOR HUMAN MILK BANK

1 2 1 1I.J. Paulaviciene , R. Vaitkeviciene , A. Liubsys , V. Usonis 1Clinic of Children Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius

2University; Neonatal Centre of Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania

7LACTOBACILLUS ACIDOPHILUS/BIFIDOBACTERIUM INFANTIS PROBIOTICS ARE BENEFICIAL TO EXTREMELY LOW GESTATIONAL AGE INFANTS IN THE CONTEXT OF HUMAN MILK EXPOSURE

1 1 1 1 2 3 1I. Fortmann , K. Hanke , J. Spiegler , K. Faust , D. Viemann , A. Stein , E. Herting , W. 1 1Göpel , C. Härtel

1 2Department of Pediatrics, University of Lübeck, Lübeck; Department of Neonatology, 3Hannover Medical School, Hannover; Department of Neonatology and General

Pediatrics, University of Essen, Essen, Germany

8PREVALENCE OF BREASTFEEDING IN INFANTS DISCHARGED FROM A NICU AND UP TO 2 YEARS OF LIFER. Sokou, E. Tavoulari, G. Ioakeimidis, S. Parastatidou, A. Makrogianni, E. Isaakidou, S. Chaniotis, D. Malliou, V. Falaina, A. KonstantinidiNICU, Nikaia General Hospital “Aghios Panteleimon”, Piraeus, Greece

9ASSESSMENT OF DEHYDRATION IN EXCLUSIVELY BREASTFED NEONATESR. Sokou, A. Makrogianni, S. Parastatidou, E. Tavoulari, G. Ioakeimidis, S. Papadakis, A. KonstantinidiNICU, Nikaia General Hospital “Aghios Panteleimon”, Piraeus, Greece

10SURGICAL NECROTIZING ENTEROCOLITIS BUT NOT SPONTANEOUS INTESTINAL PERFORATION IS ASSOCIATED WITH ADVERSE NEUROLOGICAL OUTCOME AT SCHOOL AGE

1 1 1 2 1 1A. Humberg , J. Spiegler , M.I. Fortmann , M. Zemlin , J. Marissen , I. Swoboda , T.K. 3 1 1 1Rausch , E. Herting , W. Göpel , C. Härtel

1Department of Paediatrics, University Hospital of Schleswig-Holstein, Campus Lübeck, 2Lübeck; Department of Paediatrics and Neonatology, Saarland University Medical

3Centre, Homburg/Saar; Institute of Medical Biometry and Statistics, University of Lübeck, University Hospital of Schleswig-Holstein, Campus Lübeck, Lübeck, Germany


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00Friday, October 1, 2021, 13 hrs


11THROMBOELASTOMETRY VARIABLES IN NEONATES WITH PERINATAL HYPOXIA

1 1 2 1 3,4A. Konstantinidi , R. Sokou , A.G. Tsantes , S. Parastatidou , S. Bonovas , A.K. 5Gounaris ,

2 6A.E. Tsantes , N. Iacovidou1 2 Neonatal Intensive Care Unit, Nikaia General Hospital “Aghios Panteleimon”, Piraeus; Laboratory of Haematology and Blood Bank Unit, "Attiko" Hospital, School of Medicine,

3 National and Kapodistrian University of Athens, Greece; Department of Biomedical 4 Sciences, Humanitas University; Humanitas Clinical and Research Center, Milan

5 University, Milan, Italy; Neonatal Intensive Care Unit, University Hospital of Larissa, 6 Larissa; Neonatal Department, National and Kapodistrian University of Athens, Aretaeio

Hospital, Athens, Greece

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III INFECTIONS AND INFLAMMATION Chair: R. Carr, London, UK; D. Singer, Hamburg, Germany

12EARLY – ONSET SEPSIS IN PRETERM INFANTS: DIAGNOSTICS AND TREATMENT DIFFERENCES IN 2011 AND 2016

1 2 2 2P. Aldakauskaitė , R. Brinkis , R. Tamelienė , I. Aldakauskienė 1 2Lithuanian University of Health Sciences, Medical Academy; Lithuanian University of Health Sciences, Medical Academy, Department of Neonatology Hospital of Lithuanian University of Health Sciences Kauno Klinikos, Kaunas, Lithuania

13ROAD TO THE NEW WORLD OF EARLY ONSET SEPSIS PRACTICEA. Ahmed, P. Gopalakrishnan Department of Neonatology, University Hospital of Wishaw, Glasgow, Scotland

14SEPSIS MORTALITY OF EXTREMELY PRETERM INFANTS IN GERMANY AFTER THE INTRODUCTION OF COLONIZATION SCREENING

1 1 1 1 1 2 3K. Faust , I. Fortmann , A. Humberg , J. Pagel , C. Haug , R. Kühl , B. Bohnhorst , D. 3 4 4 5 5 6 6Viemann , A. Simon , M. Zemlin , S. Poralla , A. Müller , N. Köstlin-Gille , C. Gille , M.

7 8 1 1 1Heckmann , J. Rupp , E. Herting , W. Göpel , C. Härtel1 2Department of Pediatrics, University of Lübeck, Lübeck; Department of Pediatrics,

3Diakonnissen-krankenhaus, Flensburg; Department of Neonatology, Hannover Medical 4School, Hannover; Department of Pediatrics, Saar University Homburg, Homburg;

5 6Department of Pediatrics, University of Bonn, Bonn; Department of Neonatology, 7Tuebingen University Children's Hospital, Tuebingen; Department of Neonatology and

8Pediatric Intensive Care, University of Greifswald, Greifswald; Department of Infectious Diseases and Medical Microbiology, University of Lübeck, Lübeck, Germany

15ANTIMICROBIAL SKIN PEPTIDES IN PREMATURE INFANTS: CHARACTERIZATION AND IMPACT OF PERINATAL FACTORS

1 1 1 1 2 1A. Humberg , L. Neuenburg , H. Böckel , M.I. Fortmann , C. Härtel , E. Herting , H. 3 3Hinrichs , J. Harder

1Department of Pediatrics, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck; 2 3 Department of Pediatrics, University Hospital, Würzburg; Department of Dermatology, Venerology and Allergology, Quincke Research Center, University-Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

16EPIDEMIOLOGY OF STAPHYLOCOCCUS AUREUS INFECTION IN THE NEONATAL PERIOD: A 12-YEAR SINGLE CENTER EXPERIENCE

1 1 2 1 1 1M. Tsirigotaki , I. Goniotakis , S. Maraki , E. Korakaki , O. Michopoulou , E. Hatzidaki 1 2Department of Neonatology & Neonatal Intensive Care Unit; Department of Clinical Microbiology, University Hospital of Heraklion, Crete, Greece


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00Satur 2 21day, October , 20 , 13 hrs

17EPIDEMIOLOGICAL STUDY OF HOSPITAL-ACQUIRED CONJUCTIVITIS IN A LEVEL III NEONATAL UNITI. Goniotakis, M. Tsirigotaki, A. Manoura, N.H. Anagnostatou, C. Thomou, E. Hatzidaki Department of Neonatology & Neonatal Intensive Care Unit, University Hospital of Heraklion, Crete, Greece

18VANCOMYCIN-INDUCED OTOTOXICITY IN VERY-LOW-BIRTHWEIGHT INFANTS

1* 2 2 2,3 4 5 6J. Marissen , I. Fortmann , A. Humberg , T.K. Rausch , A. Simon , A. Stein , T. Schaible , 7 8 9 10 2 2 1J. Eichhorn , J. Wintgens , C. Roll , F. Heitmann , E. Herting , W. Göpel , C. Härtel

1 2Department of Paediatrics, University of Würzburg; Department of Paediatrics; 3 4Institute of Medical Biometry and Statistics, University of Luebeck; Department of

5Paediatric Oncology, Saar University Homburg; Department of Paediatrics, University of 6 7Essen; Department of Paediatrics, University of Mannheim; Children's Hospital

8 9Leverkusen; Children's Hospital Mönchengladbach; Vestische Children's Hospital 10Datteln; Children's Hospital Dortmund, Germany; on behalf of the German Neonatal

Network.


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IV MISCELLANEOUS TOPICS� Chair: T. Curstedt, Stockholm, Sweden; T.W.R. Hansen, Oslo, Norway

19AN OBSERVATIONAL STUDY ON THE USE OF PERIPHERAL LINES VERSUS CENTRAL LINES IN NEONATAL INTENSIVE CARE UNITS

1 1 2 1 1 1A. Riskin , A. Iofe , D. Zidan , I. Shoris , A. Toropine , D. Bader 1 2Department of Neonatology, Bnai Zion Medical Center; Rappaport Faculty of Medicine, Technion, Haifa, Israel

20IS PHOTOTHERAPY ASSOCIATED WITH FUTURE CANCER RISK? A SYSTEMATIC REVIEW AND META-ANALYSIS OF 6,637,417 CHILDREN

1 2 3 4 5 6M. Abdellatif , B. Hoang-Trong , G. Tawfik , D. Papadopoulos , M. Khaled , M. Dobs , P. 7 8Duong , NT. Huy

1 2Ministry of Health and Population, Cairo, Egypt; Faculty of Medicine, Pham Ngoc Thach 3University of Medicine, Hồ Chí Minh Vietnam; Faculty of Medicine, Ain Shams University,

4 5Cairo, Egypt; Aristotle University of Thessaloniki, Thessaloniki, Greece; Faculty of 6Medicine, Cairo University, Giza, Egypt; Faculty of Medicine, Assuit University, Assuit,

7Egypt; Pediatric Department, Faculty of Medicine, University of Medicine and Pharmacy 8at Ho Chi Minh City, Vietnam; Department of Clinical Product Development, Institute of

Tropical Medicine "NEKKEN", School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan

21“NEOBRIS” A RISK SCORE FOR PREDICTING THE INCIDENCE OF HEMORRHAGE IN CRITICALLY ILL NEONATES

1 2,3 1 4 1 1R. Sokou , D. Piovani , A. Konstantinidi , A.G. Tsantes , S. Parastatidou , M. Lampridou , 1 5 6 7 8 9G. Ioakeimidis , A. Gounaris , N. Iacovidou , A.G Kriebardis , M. Politou , P. Kopterides ,

2,3 4S. Bonovas ,A.E. Tsantes1Neonatal Intensive Care Unit, "Agios Panteleimon" General Hospital of Nikea, Piraeus,

2 3Greece; Department of Biomedical Sciences, Humanitas University; Humanitas Clinical 4and Research Center, Milan, Italy; Laboratory of Haematology and Blood Bank Unit,

"Attiko" Hospital, School of Medicine, National and Kapodistrian University of Athens, 5 6Athens; Neonatal Intensive Care Unit, University Hospital of Larissa, Larissa; Neonatal

Department, National and Kapodistrian University of Athens, Aretaeio Hospital, Athens; 7Laboratory of Reliability and Quality Control in Laboratory Hematology, Department of Biomedical Science, School of Health and Caring Science, University of West Attica,

8Egaleo; Department of Blood Transfusion, Aretaieion Hospital, School of Medicine, 9National and Kapodistrian University of Athens, Athens, Greece; Intensive Care Unit,

Excela Health Westmoreland Hospital, Greensburg, Pennsylvania, USA


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22EVALUATION OF THE FAMILY-INTEGRATING CARE CONCEPT NEOPASS FOCUSING ON PARENTAL STRESS, SELF-EFFICACY, SENSE OF COMPETENCE AND THE PARENT-CHILD BONDING

2,3 1 1,3H. Seegerer , M Zeller , M Keller1Children`s Hospital Passau, Germany; ²University of Regensburg, Germany; ³Technical University of Munich, Germany

23COMPARATIVE SPECTROSCOPY OF THE 25 PAIRS OF THE FETAL (HB-F, CORD BLOOD) & MATERNAL (HB-A) HEMOGLOBIN

1 2S.G. Gokhale , V. S. Daggubati 1 2Department of Biomedical Engineering, University of Texas Arlington, USA; Chief Executive Officer, Shani Biotechnologies LLC, USA

2440 YEARS OF EXPERIENCE IN A PRIVATE NICU IN GREECEM. Saklamaki-Kontou, C. Panousopoulou, S. Mpikouvarakis, A. Ntanika, E. Apostolou NICU, Mitera Hospital, Athens, Greece


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PAST SYMPOSIA

stI Recent Advances in Neonatal Medicine

Honoring Prof. K. Riegel, MD, Munich, Germany

Tübingen, Germany, April 26 – 28, 1996

ndII Recent Advances in Neonatal Medicine

New Frontiers in Neonatology

Würzburg, Germany, October 21 - 22, 1999

rdIII Recent Advances in Neonatal Medicine

Honoring Prof. Bengt Robertson, MD, PhD, FRCPE, Stockholm, Sweden


thIV Recent Advances in Neonatal Medicine

Honoring Prof. Henry Halliday, MD, FRCPE, FRCP, FRCPCH, Belfast, UK


thV Recent Advances in Neonatal Medicine

Honoring Prof. Ola D. Saugstad, MD, PhD, FRCPE, Oslo, Norway


thVI Recent Advances in Neonatal Medicine

Honoring Prof. Mikko Hallman, MD, PhD, Oulu, Finland


thVII Recent Advances in Neonatal Medicine

Honoring Prof. Tore Curstedt, MD, PhD, Stockholm, Sweden


thVIII Recent Advances in Neonatal Medicine

Honoring Prof. Bo Sun, MD, PhD, Shanghai, China


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CITY MAP

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Congress Centre &Congress Centre &Hotel MaritimHotel Maritim

Congress Centre &Hotel Maritim

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Explore Würzburg with the freeWürzburg-App for smartphones and tablets.www.wuerzburg.de/wuerzburg-app

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GENERAL INFORMATION

SCIENTIFIC ORGANIZATIONProf. Christian P. Speer, MD, FRCPEUniversity Children's HospitalJosef-Schneider-Str. 297080 Würzburg, GermanyE-Mail: [email protected]

CONGRESS ORGANIZATION- Information, Registration, Accomodation -

Congress ● Tourismus● WürzburgImelda Mohn, Sina CharefTurmgasse 1197070 Würzburg, GermanyPhone: ++49 931 - 37 2829 Fax: ++49 931 - 37 3652E-Mail: [email protected]

CONGRESS LOCATIONCongress Centre Würzburg (CCW)Maritim Hotel Pleichertorstraße 597070 Würzburg, Germany

Registration Desk: Entrance Foyer of CCWPhone: +49 931 30 53 750

Opening Hours00 00Thursday, September 30, 2021 16 – 19 hrs30 30Friday, October 1, 2021 7 – 18 hrs30 00Saturday, October 2, 2021 7 – 18 hrs30 00Sunday, October 3, 2021 7 – 17 hrs

CONGRESS LANGUAGEEnglish

Organization Team 2021(from left to right):

Carola Wolpert, Bernd Kleinschmidt, Imelda Mohn, Christian P. Speer, Sina Charef

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FACULTY

SPONSORS

PLATINUM

CHIESI FARMACEUTICI S.P.A., PARMA, ITALY

SILVER

FISHER & PAYKEL HEALTHCARE LTD AUCKLAND, NEW ZEALAND

KARGER PUBLISHERS, S. KARGER AG BASEL, SWITZERLAND

LÖWENSTEIN MEDICAL GMBH & CO. KG BAD EMS, GERMANY

NESTLÉ DEUTSCHLAND AG NESTLÉ NUTRITION FRANKFURT a.M., GERMANY

TAKEDA PHARMACEUTICALS INC. BOSTON, MA, USA

VYGON S.A. ECOUEN, FRANCE

BRONZE

BAXTER DEUTSCHLAND GMBH UNTERSCHLEIßHEIM, GERMANY

CSL BEHRING GMBH HATTERSHEIM, GERMANY

LINDE GAS THERAPEUTICS GMBH OBERSCHLEIßHEIM, GERMANY

MEDELA MEDIZINTECHNIK GMBH & CO. HANDELS KG ECHING, GERMANY

PHILIPS GMBH MARKET DACH HAMBURG, GERMANY

FRITZ STEPHAN GMBH MEDIZINTECHNIK GACKENBACH, GERMANY

The organizers would like to express their sincere gratitude for the generous support to the following sponsors:

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SILVER

BRONZE

www.recent-advances.com

SCIENTIFIC ORGANIZATIONPROF. CHRISTIAN P. SPEER, MD, FRCPESCIENTIFIC ORGANIZATION

PROF. CHRISTIAN P. SPEER, MD, FRCPE

©Photo: A. Stürmann, Würzburg

recent advances in neonatal medicine

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