reducing perioperative cardiac complications: statins

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Reducing Perioperative Cardiac Risk: Statins Terry Shaneyfelt, MD, MPH Assoc. Professor, UAB Department of Medicine

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Review of 2 metaanalyses of RCTs on the effects of statins in the perioperative period. Watch my YouTube video describing these slides: http://youtu.be/wHYlf26AH00

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Page 1: Reducing perioperative cardiac complications: statins

Reducing Perioperative Cardiac Risk:Statins

Terry Shaneyfelt, MD, MPHAssoc. Professor, UAB Department of Medicine

Page 2: Reducing perioperative cardiac complications: statins

Devereaux PJ et al., CMAJ 2005; 173:627

Page 3: Reducing perioperative cardiac complications: statins

Cochrane Review: Statins in Vascular SurgeryData Review Through July 2012

All-cause Mortality

Nonfatal MI

Page 4: Reducing perioperative cardiac complications: statins

Effect of Perioperative Statins on Death, MI, Afib, and LOS: A Systematic Review

Arch Surg 2012;147:181 nonvasc, noncardiac vascular

Page 5: Reducing perioperative cardiac complications: statins
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• Statins should be continued in patients currently taking statins (I)

• Reasonable to give statins in patients undergoing vascular surgery (IIa)

• Consider statins in patients with ≥ 1 risk factor undergoing intermediate or high risk procedures (IIb)

Current ACC/AHA 2014 Recommendations