resporite elisa fung lindsay kugler beixian tang gabriela vargas little patients, big demands
DESCRIPTION
Design Power source Warning system/ system shut down Tire pump Pressure storage chamber Valve 1: Regulates pressure to 5psi Valve 2: Regulates pressure to 5cm H 2 O Humidifier: Humidifies and filters air Nasal cannulae Bubbling indicates system is working Pressure, humidity, & temperature sensors Bike pumpTRANSCRIPT
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Resporite
Elisa FungLindsay Kugler
BeiXian TangGabriela Vargas
Little Patients, Big Demands
![Page 2: Resporite Elisa Fung Lindsay Kugler BeiXian Tang Gabriela Vargas Little Patients, Big Demands](https://reader035.vdocument.in/reader035/viewer/2022081802/5a4d1b097f8b9ab059989717/html5/thumbnails/2.jpg)
Motivation
• Mortality rate for children under the age of 5 in Africa is double that of the rest of the developing world– 166 deaths per 1000 children
• Respiratory distress syndrome (RDS) is the leading cause of death for underweight infants– Can be treated with ventilators
• Design a reliable, easy-to-use, and low-cost ventilator for use in the developing world
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Design
Power source
Warning system/
system shut down
Tire pump
Pressure storage
chamber Valve 1: Regulates
pressure to 5psi
Valve 2: Regulates
pressure to 5cm H2O
Humidifier:Humidifies and
filters air
Nasal cannulae
Bubbling indicates system is working
Pressure, humidity, & temperature
sensors
Bike pump
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Design
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Midterm Goals
• Establish connections between components
• Test components individually and as a system• Determine length of time to fill & empty chamber• Set outgoing air pressure to 5-7 cmH2O• Determine flow rate• Humidify and filter air
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Design Process
• Component 1: Air compressor– Attempt 1: Mattress pump– Attempt 2: Tire pump
• Component 2: Pressure storage chamber• Component 3: Valves
– Valve 1 (0-150 psi)– Valve 2 (0-2 psi)
• Component 4: Humidifier
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Testing: Pressure Storage Chamber
• Purpose– Determine the time required to fill the pressure storage chamber.
• Results– Exponential relationship between time and pressure
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Testing: Regulating Pressure
• Purpose– Determine if desired output pressure (5-7 cmH2O, or 0.07-0.10 psi)
• Results– Desired pressure achieved
0 cmH2O 5 cmH2O
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Testing: Pressure Duration
• Purpose– Determine how long constant pressure will be observed at valve output with
varying chamber pressure
• Results– Determined that optimal starting pressure is 60 psi– Pressure in chamber does not last as long as desired
Time for Chamber Exhaustion
0
50
100
150
200
250
300
350
20 40 60 80Initial Pressure (psi)
Tim
e (s
econ
ds)
Time at 5 cmH2OTime until 0 psi
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Testing: Humidifier
• Purpose– Determine effects of humidifier on system
• Results– Increases amount of time chamber can sustain desired pressure– Air is humidified
Time for Chamber Exhaustion with Humidifier
0
50
100
150
200
250
300
350
20 40 60Pressure (psi)
Tim
e (s
econ
ds)
Time at 5 cmH2OTime until 0 psi
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Testing: Flow Rate
• Purpose– Determine flow rate at 5-7 cmH2O
• Results– Flow rate approximately 2.5 L/min
• Ideal flow rate is 5 L/min
Water (mL) Time (s)
100 2.07
200 4.34
300 7.13
400 9.88
500 12.34
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Conclusion
• Macroscale Prototype– Major components of system connected– Pressure of 5-7 cmH2O achieved– Air flow rate of 2.5 L/min achieved– Humidified and purified air
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Future Work
• Optimize flow rate for macroscale system• Incorporate temperature parameters• Backup system: bike pump, battery
• Microscale device to optimize current ventilator system– Electrical feedback system using LEDs and buzzer
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Acknowledgments
• Dr. Gordana Vunjak-Novakovic• Dr. Samuel Sia• Dr. Helen Towers• Dr. Jen-Tien Wung• Yukkee Cheung• Keith Yeager• Sean Burgess• Rob Maidhof• Jonathan Belmont
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Questions
?