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damage. Therefore these results suggest that ozone,in our experimental conditions, may have a role inthe treatment of diabetic complications. Other worksstudying the effects of ozone on diabetic patients withmacroangiophatic complications are in progress.

ACKNOWLEDGEMENTSThese studies were supported in part by Randox Laboratories(Antrim, UK) and the Department of Chemistryand Medical Biochemistry, University of Milan.

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artículos internacionalesresults of a non-specific immunomodulationtherapy in chronic heart failure (ACCLAIM trial):a placebo-controlled randomised trial.

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