RWTH, Peter Winandy

Electrospinning at ITAThe versatile nanofibre and nanoparticle production method

Magnus KruseInstitut für Textiltechnik der RWTH Aachen University

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ITA Personnel• 90 scientists

• 65 technical and service staff

• 200 undergraduate research assistants

ITA

ITA Divisions

• BioTex (Health)

• Mobility

• Building and Living

• Energy and Environment

• Information & Communication

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Research Network of the Biohybrid & Medical textiles (BioTex) Group

Polymer

Development

Textile Production

Chain

(Bio-) Functionalisation

Pre-clinical

Testing

Clinical Trial &

Certification

Mission: Innovation & Translation into Clinic

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• Textile Implants

• Tissue Engineering and biofunctionalisation of implants

• Medical Smart Textiles: Wearable Electronics for Health

• Wound treatment

• Hospital textiles and hygiene products

BioTex at ITA/AME

RWTH, Peter Winandy

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Collector

Fibres

F Container withpolymer solution

Non-woven/ Particles

Electrospinning - Basic principle

Electrospinning

• Electrospinning process

− High voltage field 10 – 60 kV

− Fiber/Particle diameter 100 nm – 2 µm

• Nonwoven

− Pore size up to 20 µm

− Porosity 50 - 80 %

• Examples of use

− Scaffold production

− Filters

− Drug Delivery

− And many more

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Electrospinning at BioTex

What we offer:

• Machine development and adaption

• Investigation of the spinnability ofnew materials

• Production of electrospun nonwovenelectrosprayed particles

• Scale-up of the production from labto pilot production

• Integration of substances in fibres andparticles (e.g. bioactive substances,drugs, etc.)

• In-vitro analysis of the products

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R&I Experiences

Projects

Past and recent projects

• BMBF KMU-innovativ OPRA� Development of an middle ear prothesis couplingstructre based on electrospun nonwoven

• EFRE.NRW FilaMem � Development of an electrospun membrane madefrom thermoplastic polyurethane and hyalurnoic

acid

Looking for cooperations

• Filter development (air and fluids)

• Tissue Engineering/Scaffold material

• Drug delivery applications

Thank youfor your kind attention

Magnus Kruse, M.Sc.

Biohybrids & Medical Textiles (BioTex)

Institut fuer Textile Technologie der RWTH Aachen University

Phone.: +49/(0)241/80 24741

Magnus.kruse@ita.rwth-aachen.de

http://www.ita.rwth-aachen.de