satiba 2015.09.18
TRANSCRIPT
1©Copyright Netcells Biosciences | 23 October 2013
SATiBASEPTEMBER 2015
OptiSerum™
UMBILICAL SERUM EYE DROPS
OVERVIEW
2©Copyright Netcells Biosciences | 13 March 2015
OVERVIEW
cc
3©Copyright Netcells Biosciences | 13 March 2015
COLLECTION & PRODUCTION
• Cord blood and placentas are collected from consenting donors• All donors are screened for transmissible diseases, including:
• HIV• HTLV• Hepatitis B & C• Syphilis• CMV
• Serum isolated by Aseptic Technique, filter sterilized, diluted and bottled• Sample of every batch is sent microbial cultures:
• Aerobic • Anaerobic• Fungal
• Stored frozen at -80°C, 2 year shelf life
4©Copyright Netcells Biosciences | 13 March 2015
OptiSerum™
Umbilical cord blood serum is used as a substitute for Autologous blood serum
OptiSerum™ is able to provide both lubrication and nutrition for ocular surface epithelium.
It is NOT stem cells in a bottleProperties attributed to GROWTH FACTORS and CYTOKINES
Conventional dry eye treatment: • The application of artificial tears• Topical corticosteroids or cyclosporine A• Therapeutic contact lenses
5©Copyright Netcells Biosciences | 13 March 2015
GROWTH FACTORS AND CYTOKINES
Product benefits • Contain growth factors and essential tear
components – 2-3x > autologous serum• Similar to that found in tears• Including:
• EGF
• Vitamin A
• TGF
• Substance P
• IGF-1
• NGF
• No immunogenicity• Bacteriostatic – IgG, lysozymes and
Complement• No preservatives
OptiSerum is able treat any condition that may cause delayed epithelial healing of the eye or dysfunctional tear film.
• Essential for the alleviation of dryness• Decrease inflammation• Accelerate healing of ocular surface
6©Copyright Netcells Biosciences | 13 March 2015
CONDITIONS TREATED BY OptiSerum™
Indications• Severe Dry eye with or without primary
Sjögren’s syndrome• Ocular Graft-Versus-Host-Disease (GVHD)• Persistent Epithelial Defects• Recurrent corneal erosions• Chemical burns• Neurotrophic keratitis• Post LASEK surgery• Post Corneal Transplant
7©Copyright Netcells Biosciences | 23 October 2013
OptiSerum™
8©Copyright Netcells Biosciences | 23 October 2013
NON-SJOGREN KERATOCONJUNCTIVITIS SICCA (KCS)CASE STUDY
Right eye before treatmentVA = 0.5
Left Eye before treatmentVA = 0.3
Left eye post 7 days of treatmentVA = 1.0
Right eye post 7 days of treatmentVA = 1.0
68 year old female suffering with dry eye for 6 years
Blurred vision, burning and gritty feeling
Known Glaucoma patient on Latanoprost topical treatment. No previous surgery or trauma to the eyes.
9©Copyright Netcells Biosciences | 23 October 2013
PATIENT WITH DRY MACULA AND GLAUCOMA AS CO-MORBID DISEASESCASE STUDY
Left eye before treatment Right Eye before treatment
Right eye post 7 days of treatmentRight eye post 7 days of treatment
68 year old female suffering with dry eye for 6 years
Blurred vision, burning and gritty feeling
Vision improved with treatment from 0.1 to 0.25 and 0.32
10©Copyright Netcells Biosciences | 13 March 2015
A RECENT PATIENT TESTIMONIAL
“My eyes feel better with every day passing, I can’t even imagine that less than a week ago I had almost lost all hope, and now I am able to go outside, while wearing my sun glasses of course, whereas previously this wasn’t something I could do. To share one of my frustrations I would have to close my eyes while being in the car and then end up suffering from motion sickness, this made my day to day life very difficult. I now feel like I am in control of my life again, and would like to thank Dr X for referring me to your product. I would also like to thank you for all the work you have done developing this product, it has certainly given me my hope back.”
11©Copyright Netcells Biosciences | 13 March 2015
THANK YOU
Geert KuitBiological ScientistNetcells Biosciences
Questions?