Acne 067, 124, 287, 335, 347, 348, 399, 550, 581, 616, 726 ,732, 735, 746Actin 243, 677, 682, 833Actinic keratoses 259, 270, 314, 794Adhesion molecule 214, 556, 669, 672, 694Aging 044, 209, 216, 259, 274, 291, 358, 359, 395, 396, 400, 414, 417, 451, 460, 503, 522, 559, 611, 760, 771, 772, 778, 781, 793, 799, 831Allergic encephalitis 664Alopecia 125, 133, 249, 505, 506, 507, 530, 533, 578, 584, 586, 594, 609, 621, 630, 631, 633Anaphylaxis 745Angiogenesis 005, 008, 014, 016, 019, 021, 024, 033, 038, 043, 051, 121, 208, 339, 428, 556, 752Animal models for disease 027, 034, 037, 073, 097, 117, 131, 135, 153, 167, 344, 455, 456, 502, 503, 504, 506, 507, 519, 523, 538, 590, 612, 646, 761 Antigen presenting cell 265, 344, 648, 653, 681, 694Anti-microbial peptide 111, 277, 431, 471, 705, 707, 708, 716, 725, 733, 746Antioxidant 051, 109, 248, 269, 306, 559, 685, 749, 753, 757, 779Apoptosis 080, 177, 190, 198, 252, 309, 418, 605, 671, 759, 766, 775, 787, 825, 826, 861Artificial skin and skin equivalent 010, 186, 212, 213, 218, 220, 266, 308, 380, 495, 826Atopic dermatitis 058, 074, 114, 128, 260, 277, 282, 288, 293, 311, 367, 372, 405, 433, 446, 455, 519, 536, 578, 657, 675, 679, 705, 710, 723 Autoantibody 060, 064, 084, 085, 089, 098, 227Auto-immunity 053, 058, 060, 065, 066, 068, 079, 081, 083, 084, 089, 097, 107, 110, 116, 134, 135, 253, 390, 507, 533, 578, 691, 767 b cell 134, 456, 691, 720bacteria 256, 341, 707bacterial infections 380, 719, 734, 739, 743barrier function 401, 404, 405, 410, 424, 430, 432, 433, 439, 441, 445, 448, 449, 452, 455, 458, 462, 467, 468, 472, 474basal cell carcinoma 50, 156, 167, 181, 182, 187, 188, 204, 206, 387, 388, 868basement membrane 236, 240, 453, 482biochemistry 334biofilm 012bowen’s disease 148brAf 142, 863bullous disease 053, 097, 105, 118, 134, 135, 224cadherin 215, 242, 454calcium 030, 437, 520, 540, 549, 551, 560, 629, 787cAMP 054, 055, 056, 057, 059, 554cancer genetics 144, 146, 147, 160, 164, 168, 170, 171, 172, 192, 570, 852capsaicin 200, 307, 320carcinogenesis 141, 142, 145, 155, 158, 159, 161, 174, 176, 178, 179, 180, 182, 183, 188, 189, 191, 194, 199, 200, 202, 208, 385, 542, 562, 658, 687, 798, 824catecholamines 004catenin 228, 582, 636cathelicidin 022, 111, 703, 721cDnA cloning 640cell adhesion 063, 064, 160, 225, 234, 243, 439, 493cell biology 441, 567, 615, 634, 843

cell cycle control 194, 561, 567, 579, 599, 603, 652, 785

cell motility 041, 048, 158, 221, 236, 237, 494, 566, 801chemokine 009, 061, 077, 087, 091, 101, 120, 129, 283, 324, 347, 647, 672, 718, 808, 810cholesterol 304, 480chondroitan sulfate 070claudin 410clinical research 062, 130, 136, 246, 247, 249, 254, 256, 257, 261, 262, 278, 284, 286, 289, 290, 295, 300, 302, 303, 311, 314, 318, 320, 321, 323, 332, 345, 346, 348, 365, 391, 394, 395, 448, 457, 844, 855clinical trials 264, 267, 274, 279, 306, 322, 325, 336, 478, 608collagen 085, 221, 229, 230, 234, 240, 305, 336, 400, 509, 517, 776collagenase 050, 554connective tissue 500, 508contact dermatitis 009, 113, 692, 744contact hypersensitivity 112, 656, 662, 663, 665, 666, 692, 693, 700, 729, 737, 765, 782cortico steroids 127, 304, 693, 792cutaneous t cell lymphoma 151, 154, 190, 196, 197, 252, 271, 273, 283, 298, 301, 312, 317, 324, 329, 667, 795 cyclooxygenase 138, 325cyclosporine A 326cytochrome P450 718cytokine 006, 041, 067, 088, 104, 105, 117, 124, 132, 137, 139, 141, 149, 154, 300, 331, 415, 445, 531, 642, 647, 651, 688, 689, 697, 704, 712, 715, 718, 722, 730, 745, 780, 824cytokine receptors 096, 484, 737cytoskeleton 577, 682cytotoxicity 411, 686, 724, 743, 744Darier’s disease 210, 520Defensin 058, 300, 431, 445, 709, 764Dendritic cell 099, 103, 316, 330, 340, 640, 641, 649, 650, 651, 658, 659, 660, 664, 667, 668, 670, 674, 677, 702, 724, 727, 728 Dermatologic surgery 001, 279, 366, 381, 382Dermatopathology 284, 332, 354, 429, 841Dermis 213, 218, 226Desmocolin 402Desmoglein 068, 118, 180, 217, 454, 534, 739Desmosome 063, 160, 180, 210, 224, 228, 242, 243, 534Desquamation 338, 444, 466Development biology 215, 350, 472, 582, 592, 601, 604, 614, 615, 626, 627, 629, 634, 639, 855Differentiation 205, 240, 403, 407, 409, 423, 425, 426, 438, 441, 443, 450, 454, 469, 473, 487, 551, 564, 592, 595, 596, 651DnA mutation 477, 488, 512DnA repair 147, 168, 193, 202, 350, 420, 467, 470, 522, 618, 751, 760, 791DnA virus 712, 713DtI 592eccrine gland 292, 427eczema 260, 343, 410effectiveness research 258, 334, 381, 384eGf 200, 572, 801eGf-like growth factors 573elastin 040, 219, 222, 223endothelial cell 003, 009, 028, 029, 047, 092, 701, 857eosinophil 078epidemiology 287, 311, 349, 350, 351, 352, 353, 355, 356, 357, 361, 363, 364, 365, 367, 371, 372, 374, 375, 378, 379, 381, 383, 389, 390, 392, 827, 860

sID Keyword Index

www.jidonline.org s169

epidermal growth factor receptor 120, 225, 346, 432, 541, 542, 544, 561, 571, 573, 748epidermal permeability barrier 209, 401, 402, 437, 539, 616epidermolysis bullosa 236, 328, 336, 453, 481, 483, 509, 511, 517erythema 046extracellular matrix 050, 216, 219, 220, 222, 238, 241, 328, 428, 473, 778fas 146, 196fatty acid 076fibrillin 223, 547fibroblast 023, 032, 035, 140, 216, 220, 230, 233, 239, 566, 617, 650, 784, 831fibronectin 031, 032, 669fibrosis 082filaggrin 398, 443, 496, 519fungal therapy, fungus 254, 258, 464, 465, 711G protein 541, 542, 748G protein coupled receptors 002, 126, 792, 840, 853 Gangliosides 574, 866Gene expression 026, 034, 052, 133, 142, 143, 162, 184, 196, 266, 339, 450, 463, 487, 499, 502, 504, 525, 535, 603, 606, 615, 671, 720, 817, 830, 853Gene regulation 072, 179, 201, 449, 472, 486, 491, 499, 508, 521, 534, 536, 582, 583, 604, 610, 626, 631, 717, 742, 786, 798, 807, 845Gene therapy 478, 481, 492, 497, 516, 537Genetic disease 073, 108, 256, 322, 429, 479, 482, 484, 489, 492, 493, 494, 498, 499, 501, 502, 503, 505, 506, 513, 516, 523, 528, 530, 532, 538, 539, 623Genodermatosis 024, 421, 475, 476, 477, 481, 495, 500, 512, 524, 537, 598, 618Genomics 144, 169, 173, 535, 536, 844Genotyping 498, 529, 533Glycosaminoglycans 773Growth factor/growth factor receptors 018, 044, 156, 319, 555, 557, 558, 574, 575 Hailey-Hailey disease 477Hair 156, 440, 456, 512, 521, 527, 529, 561, 579, 580, 584, 585, 586, 587, 588, 590, 591, 594, 595, 597, 598, 600, 602, 603, 605, 606, 607, 608, 609, 610, 612, 613, 617, 619, 620, 621, 622, 623, 624, 625, 626, 627, 628, 629, 632, 633, 634, 635, 636, 637, 638, 639, 740, 843Health services research 354, 355, 364, 371, 379, 386, 391Heat shock protein 069, 630, 658, 768Hemidesmosome 225, 235Herpes simplex 245, 731Hirsutism 605HIV 433, 728HlA 066, 489, 510, 532Homeobox genes 036Human papillomavirus 148, 149, 175, 195, 490Hyaluronic acid 070, 209, 213, 218, 261, 432, 447, 706, 806Hyperkeratosis 528Hyperkeratotic skin diseases 075 Ichthyosis 373, 429, 443, 496, 514, 515, 539Ige 085Immunology 079, 092, 116, 121, 122, 123, 131, 150, 164, 191, 231, 516, 641, 642, 643, 652, 655, 660, 667, 668, 669, 671, 673, 674, 677, 680, 689, 691, 700, 701, 722, 741, 767Infection 012, 037, 338, 716, 723, 727, 736Infectious disease 690, 735Inflammation 005, 008, 022, 031, 036, 049, 051, 061, 067, 071, 072, 073, 087, 088, 090, 092, 101, 105, 114, 120, 121, 126, 127, 129, 131, 136, 137, 139, 145, 208, 247, 272, 282, 284, 288, 333, 335, 347, 480, 513, 514, 515,

550, 575, 653, 655, 661, 687, 715, 726, 744, 780, 800Innate immunity 298, 703, 706, 707, 716, 719, 725, 727, 733, 734, 735, 736, 740, 741, 764Insulin-like growth factor 189, 422, 547, 555, 793Integrin 071, 234, 235, 237, 482, 493, 494, 555, 804 Interferon 072, 094, 125, 250, 683, 712, 713, 810 Interleukin 075, 093, 104, 145, 701, 752, 846Ions 030, 048, 452, 545, 796Kaposi’s sarcoma 742Keloid 232Keratinocyte 007, 013, 016, 025, 026, 077, 089, 091, 093, 094, 100, 118, 132, 138, 158, 161, 205, 211, 237, 269, 397, 398, 399, 402, 403, 407, 408, 413, 421, 422, 423, 425, 426, 434, 435, 438, 440, 450, 461, 467, 470, 485, 486, 511, 544, 545, 546, 548, 549, 551, 553, 556, 557, 563, 568, 573, 592, 595, 604, 637, 696, 704, 705, 714, 717, 733, 741, 743, 753 ,759, 768, 777, 778, 785, 847Keratins 007, 040, 042, 107, 322, 435, 440, 492, 511, 513, 527, 537, 632Keratosis 251, 526Knock-out mice 020, 039, 174, 447, 483, 600lamellar bodies 421, 466laminin 211langerhans cell 074, 099, 113, 115, 176, 316, 649, 666, 676, 729leprosy 394, 720linkage association/analysis 510, 529, 530, 623 lipids 401, 404, 462, 772, 779loricrin 491lupus erythematosus 070, 130, 257, 310, 643, 758lymphocyte 052lymphoma 296, 315, 351Macrophage 006, 337, 345, 713, 730MAP kinase 086, 221, 229, 564, 570, 575, 576, 747, 749, 822, 825, 863, 865 Mast cell 276, 342, 619, 745, 758, 788Matrix biology 230, 233, 239, 483, 806Medical decision making 813 Melanin 248, 290, 761, 783, 802, 803, 811, 823, 850, 854Melanocyte 430, 696, 790, 791, 797, 802, 804, 805, 821, 822, 829, 830, 832, 834, 843, 847, 853, 865, 868Melanoma 035, 043, 047, 169, 171, 184, 198, 214, 250, 309, 330, 332, 353, 362, 363, 391, 548, 565, 702, 797, 798, 801, 804, 805, 807, 808, 809, 810, 812, 816, 817, 825, 826, 827, 828, 830, 832, 833, 835, 836, 837, 838, 839, 841, 842, 844, 845, 846, 849, 851, 852, 856, 858, 859, 861, 863, 864, 866, 867Melanoma, epidemiology 349, 362, 363, 386, 809, 835, 836, 837, 838, 867 Metabolism 470Metalloproteinase 047, 162, 227, 337, 650, 771, 776, 784MHc 490Microarray 065, 197, 201, 266, 468, 480, 617, 688, 814Monocyte 397, 673Morphology 813, 834Mutation 461, 476, 509, 518, 528, 828Mycosis fungoides 265, 273, 329, 795nail 464, 465, 527, 632nerve 010, 226, 292, 320, 428, 504, 633nerve growth factor 562neural transmitters 276neurofibromatosis 203

Keyword Index

s170 Journal of Investigative Dermatology (2009), Volume 129

neurofilament 226neurokinins 670neuropathy 292, 645neuropeptides 061, 103, 255, 642, 657, 680, 696, 792neutrophil 053, 062, 552, 719, 734nevus 362, 824, 841, 860nitric oxide 569nK cell 296, 738notch 436oncogene 543, 845, 852oral cavity 398outcomes research 253, 346, 368, 374, 375, 384, 385oxygen radicals 412, 419, 777p53 152, 181, 192, 195, 198, 206, 859Parasites 098Patch test 700Patch/hedgehog 204, 378, 611Pemphigus 060, 064, 080, 217Pemphigus foliaceus 227Pemphigus vulgaris 063, 084, 224, 390, 406Percutaneous absorption 323Permeability barrier 427Pharmacology 054, 055, 056, 057, 059, 126, 167, 334, 644Phosphatase 177, 549, 571Phospholipase 187Phosphorylation 543Photobiology 202, 279, 312, 321, 370, 459, 704, 748, 754, 757, 761, 762, 766, 767, 775, 780, 781, 794, 796, 803Photodynamic therapy 305, 766, 775, 787, 795Pigmentation 110, 290, 430, 613, 750, 754, 783, 799, 800, 802, 803, 811, 813, 818, 819, 823, 829, 834, 835, 836, 837, 838, 840, 848, 855, 857, 859, 862, 867, 868Platelet-activating factor 003, 115, 174, 788 Platelet-derived growth factor 164, 566 Polymerase chain reaction 487, 816 PPAr 095, 434, 463, 583, 593, 631Profilaggrin 409, 458Proliferation 447, 514, 558, 565Prostaglandins 086, 584, 609, 612, 649, 656, 847Protease 114, 268, 407, 444, 446, 473, 515, 722, 840Protease inhibitors 159, 576Protein kinase 152, 166, 210, 438, 543, 762Proteoglycans 265Proteomics 207, 451, 459, 590, 699, 814Pruritus 086, 352, 360, 369, 442, 657Psoriasis 016, 033, 052, 054, 055, 056, 057, 059, 069, 071, 075, 076, 077, 081, 088, 090, 091, 093, 094, 095, 096, 100, 101, 103, 104, 108, 109, 111, 115, 117, 119, 132, 136, 137, 139, 244, 255, 272, 275, 280, 282, 287, 297, 299, 313, 316, 326, 327, 331, 343, 344, 356, 364, 374, 375, 376, 377, 389, 393, 403, 422, 489, 510, 523, 525, 532, 535, 552, 560, 645, 646, 684, 695, 697, 708, 714, 721, 730Psychology 245, 255, 383, 645Quality care 302, 303, 384, 386Quality of life 245, 313, 348, 360, 367, 368, 370, 373, 389, 710ras 163, 598, 599, 659receptor 090, 222, 563, 593, 808registry 351retinoid 133, 270, 308, 388, 408, 460retinoid receptors 408retrovirus 175, 490rosacea 022, 246, 268scID mouse 297scleroderma 082, 122, 140, 508sebaceous glands 399, 581, 583, 593, 746

sezary syndrome 173, 197, 271signal transduction 002, 020, 023, 129, 178, 186, 217, 342, 406, 461, 540, 545, 550, 553, 554, 557, 568, 570, 572, 597, 600, 635, 638, 639, 644, 699, 807skin graft 010sphingosine 405, 520squamous cell carcinoma 148, 153, 155, 157, 162, 163, 165, 166, 176, 185, 186, 187, 191, 192, 199, 201, 205, 207, 337, 339, 340, 388, 577, 654, 686, 751, 794stem cell 025, 045, 144, 155, 161, 203, 229, 267, 294, 328, 436, 558, 579, 589, 591, 599, 610, 611, 614, 625, 638, 851 stratum corneum 338, 394, 427, 446, 448, 452, 466substance P 670sunlight 251, 370superantigen 646systemic lupus erythematosis 099, 285, 643 t cell 068, 079, 082, 095, 100, 106, 110, 119, 122, 123, 128, 190, 263, 301, 324, 340, 624, 644, 648, 652, 653, 654, 655, 660, 661, 665, 672, 673, 678, 680, 681, 682, 684, 688, 689, 690, 694, 695, 697, 699, 729, 738t cell lymphoma 154, 318t regulatory cell 081, 083, 102, 107, 112, 123, 157, 271, 312, 662, 663, 664, 665, 666, 693, 782tGf-beta 042, 049, 140, 241, 563, 602, 781th1/th2 128, 276, 280, 293, 531, 656, 668, 679, 683, 692, 695therapeutics 002, 013, 024, 259, 273, 288, 299, 309, 317, 333, 343, 524, 560, 591, 710, 812tight junction 242, 439tnf-alpha 021, 327, 525, 576, 723, 762, 773, 789toll-like receptors 268, 298, 333, 679, 706, 708, 724, 725, 731, 737, 790toxicology 411, 415transcription 179, 468, 485, 491, 531, 596transcription factors 153, 163, 436, 521, 567, 601, 627, 661, 717, 786, 789, 865transgenic mice 181, 185, 568, 596, 601, 635, 715transglutaminase 416tumor infiltrating lymphocyte 157, 654, 686, 687 tumor progression 021, 151, 203, 207, 562, 806, 812tumor suppressor gene 147, 166, 185, 476, 805tyrosinase 248, 799, 800, 811, 814, 815, 848, 854tyrosine kinase 039, 178, 250, 342, 564, 572Ulcer 018, 278, 319, 365Ultraviolet 008, 046, 138, 141, 152, 177, 189, 193, 194, 204, 269, 459, 541, 546, 571, 648, 749, 750, 751, 752, 753, 755, 756, 758, 759, 763, 764, 765, 769, 770, 771, 772, 773, 774, 776, 777, 779, 782, 783, 784, 785, 786, 788, 789, 790, 791, 793, 796, 831 Urokinase 866Vaccine 124, 330, 674, 690, 698, 702Virus 062, 731, 742Vitamin D 143, 297, 329, 353, 378, 385, 404, 431, 485, 602, 721, 842Vitiligo 820, 829Warts 175Wound healing 001, 003, 004, 006, 007, 012, 014, 015, 017, 018, 019, 020, 023, 025, 026, 027, 030, 031, 032, 034, 036, 037, 039, 040, 041, 042, 044, 045, 049, 050, 127, 211, 235, 239, 251, 267, 278, 281, 304, 319, 361, 478, 540, 574, 614, 624, 625Xeroderma pigmentosum 168, 193, 618, 828

Keyword Index

www.jidonline.org s171