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BACKGROUND

SingHealth Investigational Medicine Unit (IMU) is an early phase clinical research unit, which supports the research of commercial partners and investigators. The unit is located at Block 7, Level 7 of Singapore General Hospital (SGH) and provides services to facilitate:

KEY OBJECTIVES

De�ning the future of medicine through the conduct of early phase clinical research

Translating innovations into improved patient care

Educating and training researchers in early phase clinical trial research ethics and methodology

Developing thought leadership through research innovations

Proof of concept, '�rst-in-man' or early stages of clinical development of investigational drugs, vaccines and devices

Identi�cation and validation of novel disease biomarkers

PET, CT and MRI facilities

Nuclear medicine

Investigational and chemotherapy pharmacy services

CAP-certi�ed pathology laboratories

We have ready access to various research services, including:

We champion medical research practice and methodology to train doctors, pharmacists, nurses, coordinators and technologists in clinical trial management.

Pharmacokinetics and pharmacodynamics studies

Healthy volunteer and patient trials

CORE STRENGTHS

We specialise in early phase clinical research. Our projects are supported by a team of dedicated and well-trained Clinical Research Coordinators, Clinical Research Nurses and Resident Physicians. The unit specialises in studying diseases that impact patients in Asia, including:

CORE SERVICES

Case Report Form (CRF) design

Specimen collection, handling and processing

Coordination with external central laboratories

Project management of trials

Conducting trials that adhere to Singapore-Good Clinical Practice, supported by a robust healthy volunteer database

FACILITIES

Thirty beds

Two consultation rooms

Dedicated subject recruitment and screening rooms

Two-bed chronobiology suite, managed by Duke-NUS Graduate Medical School Singapore

24/7 CCTV

Storage space for IP

Internal Quality Assurance (QA) system

Clinical pharmacology and pharmacogenetic testing

Sample processing room

2-8oC, -30oC and -80oC refrigerators with 24/7 electronic temperature logs linked to a central alarm system

Wireless, real-time ECG/telemetry

Temperature-controlled centrifuges

HAEMATOLOGY

GASTROENTEROLOGY

EMERGING INFECTIOUS DISEASE

ONCOLOGY

CARDIOLOGY

DIRECTOR’S BIO

Ms Sue Tee, Director, Administration & Operations, Investigational Medicine Unit, SingHealth.

In addition to her role in Administration and Operations at Investigational Medicine Unit, SingHealth, Sue holds the Director, Clinical Trials Development role in SingHealth. Her extensive knowledge of the clinical trials scene enables her to assist in collaborations among multi-sites. In this capacity, she serves as a liaison between the biopharmaceutical companies and SingHealth institutions.

The content is correct at the time of printing.©2015 SingHealth O�ce of Research. All rights reserved.

SingHealth Investigational Medicine Unit (IMU)

Singapore General HospitalBlock 7, Level 7Outram RoadSingapore 169608

Tel: (+65) 6323 7533Fax: (+65) 6323 3971Email: imu@singhealth.com.sg

DIRECTOR’S BIO

Assoc. Prof Darren Wan-Teck Lim, Director of Investigational Medicine Unit, SingHealth and Senior Consultant, Division of Medical Oncology, National Cancer Centre Singapore (NCCS).

Assoc. Prof Lim is also co-group leader at the NCCS-MPI-IMCB laboratory at the Institute of Molecular and Cell Biology (IMCB) Singapore. He is Associate Professor at Duke-NUS Graduate Medical School Singapore and adjunct clinical tutor at the Yong Loo Lin School of Medicine, National University of Singapore. His clinical interests are in lung, thyroid, and head and neck cancers. His research interests are in early phase clinical trials with developmental biological correlates.