standarde medicale de diagnostic i tratament …old.ms.md/_files/1951-6.chimioterapie.pdf ·...

medicale de diagnostic �i tratamentSTANDARDE

chimioterapie

1

1 2 3 4 5 6 7 8C00-C06, a) medicina

primar�Analiza general� a sîngelui + trombocite N1

1 CF: Cisplatin 100mg/m2 i.v. perf. 1zi,

50mg 3

C09-C14, Analiza general� a urinei N1

5Fluoruracil 750mg i.v. 1-5zi fiecare 3-4 s�pt.;

250mg 15

C30-C32 Glucoza N1 Metotrexat 40-60mg/m2 i.v. o dat� pe s�pt.;

10mg 10

Ureea N1 LFC: Leucovorin 30mg/m2

i.v. 1-3zi, 10mg 15

Cancerul pavimentos al regiunii capului �i gîtului (buza,limba, gingia, plan�eul bucal, palatul moale, amigdala, orofaringele, rinofaringe-le, sinusul piriform, hipofaringele, cavitatea bucal�, laringele, fosele nazale, sinusurile faciale

Creatinina N1 5Fluoruracil 750mg i.v. 250mg 9

8

Tratamentul substan�a/manopera

Doza, unitatea de

m�sur�

Num�rul de

prize/pastile/fiole/flaco

ane recomanda

te

Durata tratamen-

tului recoman-dat (zile)

CIM unitatea nozologic� Etapa acord�rii asisten�ei medicale

Denumirea comun� interna�ional� a investiga�iilor

Num�rul investi-ga�iilor

CHIMIOTERAPIA TUMORILOR MALIGNE

2

Bilirubina N1 1-3zi, Cisplatin 120mg/m2

i.v. perf. 4zi fiecare 3-4 s�pt.;

50mg 4

Cancerul nediferen�iat alrinofaringelui

Proteina total� N1 TxtC: Docetaxel 75mg/m2

i.v. perf. 1zi, 80mg 2

Albumina N1 Cisplatin 75mg/m2 i.v. perf. 1zi fiecare 3-4 s�pt.;

50mg 3

ALT N1 TxtF: Docetaxel 85mg/m2

i.v. perf. 1zi; 80mg 2

AST N1 5FU 750mg i.v. 1-5zi fiecare 3-4 s�pt.

250 15

Fosfataza alcalin� N1

R-grafia pulmonar� N1

ACOP+Pt: Doxorubicin 50mg/m2

50mg 10

i.v. 1zi, Ciclofosfan 600mg/m2 i.v. 1zi,

200mg 5

b) medicina specializat� de laborator

Ultrasonografia or-ganelor interne N1

Vincristin 2mg i.v. 1zi, 1mg 2

Alte investiga�ii – dup� indica�ii

Cisplatin 100mg/m2 i.v. 50mg 4

R-grafia pulmonar� N1 perf. 4zi, Prednizolon 1mg/kg per os 1-5 zi, fiecare 3-4 s�pt.;

5mg 16

3

PBF: Cisplatin 100mg/m2


Bleomicyn 16mg/m2 i.v. 15mg 8

1-4 zi, 5FU 750mg i.v. 1-4zi, fiecare 4s�pt.;

250mg 12

BEC: Cisplatin 100mg/m2


Epirubicin 70mg/m2 i.v. 10 12

1zi; Bleomicyn 16mg/m2 i.v. 1-4 zi;

15mg 8

IFL: Ifosfamid 1200mg/m2

i.v. perf. pe 1g 10

fond de Uromitexan 1200mg/m2 i.v. 1-5zi,

400mg 25

Acid folinic 30mg/m2 30mg 8

i.v. 1-5zi, 5FU 425mg/m2 i.v. 1-5zi.

250 15

C07-C08 a) medicina primar�

Analiza general� a sîngelui + trombocite N1

1 CAP: Ciclofosfan 500mg/m2

i.v. 1zi, 200mg 5

Analiza general� a urinei N1

Doxorubicin 50mg/m2 50mg 10

Tumorile maligne ale glandei parotide, glandelor salivare (adenocarcinoame �i cilindroame)

Glucoza N1 i.v. 1zi, Cisplatin 100mg/m2

i.v. perf. 1zi fiecare 3 s�pt.;50mg 4

8

4

Ureea N1 PBF: Cisplatin 100mg/m2


Bilirubina N1 PLF: Cisplatin 100mg/m2


Proteina total� N1 Leucovorin 30mg/m2 10mg 20

Albumina N1 i.v. 1-4zi, 5FU 750mg i.v. 1-4zi, fiecare 3 s�pt.

250mg 12

ALT N1AST N1Fosfataza alcalin� N1






C15 a) medicina primar�

Analiza general� a sîngelui + tromb-cite N1


50mg 4 8

Creatinina N1 Bleomicyn 16mg/m2 i.v. 1-4 zi, 5FU 750mg i.v. 1-4zi, fiecare 4s�pt.

15mg 250mg

8 12

5



250mg 15

Cancerul esofagului Glucoza N1 ECF: Epirubicin 50mg/m2

i.v. 1zi, 10mg 10

Ureea N1 Cisplatin 60mg/m2 i.v. 50mg 2

Creatinina N1 perf. 1zi, 5FU 750mg i.v. 1-5zi, fiecare 3 s�pt.;

250mg 15

Bilirubina N1 TC: Paclitaxel 180mg/m2

perf. 1zi, 210mg 2

Proteina total� N1 Cisplatin 60mg/m2 i.v. perf. 1zi, fiecare 2 s�pt.

50mg 2

Albumina N1







6

C-16 a) medicina primar�

Analiza general� a sîngelui + trombo-cite N1

1 FAP: Cisplatin 100mg/m2



5FU 750mg i.v. 1-5zi, 250mg 15

Cancerul stomacului Glucoza N1 Doxorubicin 50mg/m2 i.v. 1zi, fiecare 4 s�pt.;

50mg 2

Ureea N1 EAP: Doxorubicin 20mg/m2

i.v. 1, 7zi, 50mg 2

Creatinina N1 Cisplatin 40mg/m2 i.v. 50mg 4

Bilirubina N1 perf. 2, 8zi, Etoposid 120mg/m2 i.v. perf. 4, 5, 6zi, fiecare 4 s�pt.;

100mg 6

Proteina total� N1 LF: Leucovorin 30mg/m2 i.v. 1-5zi, 5FU

10mg 25

Albumina N1 425mg/m2 i.v. 1-5zi fiecare 3 s�pt.;

250mg 15

ALT N1 ELF: Etoposid 120mg/m2

i.v. perf. 1-100mg 6

AST N1 3zi, Leucovorin 30mg/m2 i.v. perf. 1-3zi,

10mg 15

Fosfataza alcalin� N1 5FU 500mg/m2 perf. 1-3zi, fiecare 3-4 s�pt.;

250mg 9

R-grafia pulmonar� N1 DC: Docetaxel 85mg/m2 i.v. perf. 1zi,

80mg 2

12

7

Cisplatin 75mg/m2 i.v. perf. 1zi, fiecare 3 s�pt.

50mg 3



CEACa-19-9Alte investiga�ii – dup� indica�ii



CCNU: 80mg/m2 per os o dat� în 6 s�pt.

20mg 8

Cancerul intestinului sub�ire Glucoza N1

Ureea N1Creatinina N1

Bilirubina N1

Proteina total� N1

Albumina N1

ALT N1AST N1Fosfataza alcalin� N1R-grafia pulmonar� N1



1 5FU: 425mg/m2 i.v. peste o zi N6-8, fiecare 3 s�pt.;

250mg 25 12

8





C18, C19, C20 a) medicina primar�


1 Mayo: Leucovorin 20mg/m2

i.v. 1-5zi, 30mg 15


5FU 425mg/m2 i.v. 1-5zi, fiecare 4 s�pt.;

250mg 15

Cancerul Glucoza N1 LFP: CCNU 80mg/m2 20mg 8

colonului, cancerulretosigmei, rectului

Ureea N1 per os 1zi, 5FU 400mg/m2

i.v. 1-3zi, 250mg 9

Creatinina N1 Cisplatin 120mg/m2 i.v. perf. 4zi, fiecare 6 s�pt.;

50mg 4

Bilirubina N1 MLF: Mitomocin C 10mg/m2 i.v. 1zi,

20mg 1

Proteina total� N1 Leucovorin 30mg/m2 30mg 10

Albumina N1 i.v. perf. 2-5zi, 5FU 425mg/m2 i.v. 2-5 zi, fiecare 4 s�pt.;

250mg 12

ALT N1 Capecitabime: 2500mg/m2

per os 14 zile, fiecare 3 s�pt.;

500mg 120

8

9

AST N1 Irinotecan: 350mg/m2i.v. perf. fiecare 3 s�pt.;

100mg 6

Fosfataza alcalin� N1 Raltitrexed: 3mg/m2 i.v. fiecare 3 s�pt.;

R-grafia pulmonar� N1 Oxaliplatin: 130mg/m2 i.v. perf. fiecare 3 s�pt.

50mg 3



CEAAlte investiga�ii – dup� indica�ii





50mg 4



250mg 15

Cancerul anal Glucoza N1 MF: Mitomicin C 10mg/m2


Ureea N1 5FU 425mg/m2 i.v. 1-5zi, fiecare 4 s�pt.

250mg 15

Creatinina N1

Bilirubina N1

8

10


Albumina N1





Tomografia computerizat� �i

alte investiga�ii – dup� indica�ii




AF: Doxorubicin 10mg 10


60mg/m2 i.v. 1zi, 5FU 500mg/m2 i.v. 1-4 zi, fiecare 3 s�pt.;

250mg 12

Cancerul hepatic primar Glucoza N1 PIAF: Cisplatin 80mg/m2 i.v. perf. 1 zi,

50mg 3

Ureea N1 Doxorubicin 40mg/m2 50mg 10

Creatinina N1 i.v. 1zi, 5FU 400mg/m2 250mg 12

1 8

11

Bilirubina N1 i.v. 1-4zi, Interferon alfa 5mlnUI/m2 s.c. 1-4zi, fiecare 3-4 s�pt.

3mlnUI 12


Albumina N1





Alfa-fetoproteina Alte investiga�ii – dup� indica�ii


C23, C24 a) medicina primar�


1 5FU 500mg/m2 i.v. 1-5zi, fiecare 4s�pt.;

250mg 15


Gemcitabin 1000mg/m2 i.v. perf. 1, 8, 15zi, fiecare 4 s�pt.;

1g 6

Cancerul vezicii biliare,c�ilor biliare

Glucoza N1 Docetaxel 100mg/m2 i.v. perf. fiecare 3 s�pt.;

80mg 2

8

12

Ureea N1 FLM: 5FU 400mg/m2 250mg 12

Creatinina N1 i.v. 1-4zi, Leucovorin 30mg/m2 i.v. 1-4zi,

10mg 10

Bilirubina N1 Mitomicin 8mg/m2 i.v. 1zi fiecare 4 s�pt.

20mg 1


Albumina N1









1 5FU 500mg/m2 i.v. 1-5zi fiecare 4 s�pt.;

250mg 15


AF: Doxorubicin 30mg/m2

i.v. 1, 8zi, 10mg 10

Cancerul pancreatic Glucoza N1 5FU 500mg/m2 i.v. 1, 3, 5, 8, 10zi fiecare 3s�pt.;

250 15

10

13

Ureea N1 Mayo: Leucovorin 20mg/m2

i.v. 1-5zi, 5FU 10mg 25

Creatinina N1 425mg/m2 i.v. 1-5zi, fiecare 4 s�pt.;

250mg 15

Bilirubina N1 Gemcitabin 1000mg/m2 i.v. perf. 1, 8, 15zi fiecare 4s�pt.

1g 6


Albumina N1





Ca-19-9CEAAlte investiga�ii – dup� indica�ii





50mg 4 10

14


5Fluoruracil 750mg i.v. 1-5zi fiecare 3-4 s�pt.

250mg 15

Cancerul traheei, bron�ilor�i pulmonului

Glucoza N1 EP: Cisplatin 75mg/m2 50mg 3

(non-micro- Ureea N1 i.v. perf. 1zi, Etoposid 120mg/m2 1, 3, 5zi fiecare 4

100mg 6

celular) Creatinina N1 CAP: Ciclofosfan 500mg/m2

i.v., 200mg 5

Bilirubina N1 Doxorubicin 50mg/m2 10mg 10

Proteina total� N1 i.v., Cisplatin 80mg/m2 i.v. perf. 1zi fiecare 4 s�pt.;

50mg 3

Albumina N1 MVP: Mitomicin 10mg/m2

i.v. 1 zi, 20mg 1

ALT N1 Vinblastin 5mg/m2 i.v. 5mg 2

AST N1 1,8zi, Cisplatin 50mg/m2 i.v. perf. 1zi fiecare 4 s�pt.;

50mg 2

Fosfataza alcalin� N1 MIC: Mitomicin 10mg/m2

i.v. 1zi, 20mg 1

R-grafia pulmonar� Ifosfamid 2g/m2 i.v. 1- 1g 15

N1 5zi, Cisplatin 75mg/m2 i.v. perf. 1zi fiecare 4s�pt.;

50mg 3

TC: Paclitaxel 175mg/m2

perf. 1zi, 210mg 2

15

Cisplatin 80mg/m2 i.v. perf. 1zi, fiecare 3s�pt.;

50mg 3

DC: Docetaxel 75mg/m2 i.v. perf. 1zi, Cisplatin

80mg 2



75mg/m2 i.v. perf. 1zi, fiecare 3 s�pt.;

50mg 3


GC: Gemcitabin 1000mg/m2

i.v. perf. 1, 1g 6

R-grafia pulmonar� N1 8, 15zi, Cisplatin 80mg/m2

i.v. perf. 1zi fiecare 4 s�pt.50mg 3

Cancerul pulmonarmicrocelu-lar

+ Tomografia computerizat� a creierului

EP: Cisplatin 80mg/m2 50mg 3

i.v. perf. 1zi, Etoposid 120mg/m2 1, 2, 3zi fiecare 3 s�pt.;

100mg 6

CAV: Ciclofosfan 1000mg/m2,

200mg 10

Doxorubicin 50mg/m2, 50mg 2

Vincristin 1,4mg/m2 i.v. 1zi fiecare 3 s�pt.;

1mg 2

16

CAM: Ciclofosfan 1000mg/m2,

200mg 10


Metotrexat 30mg/m2 i.v. 1zi fiecare 3s�pt.;

50mg 2

CDE: Ciclofosfan 1000mg/m2 i.v. 1zi,

200mg 10


i.v. 1zi, Etoposid 100mg/m2

1, 2, 3zi fiecare 3 s�pt.;100mg 6

CE: Carboplatin 300mg/m2


Etoposid 120mg/m2 1, 2, 3zi fiecare 3 s�pt.;

100mg 6

VIP: Etoposid 100mg 6

75mg/m2, Ifosfamid 1200mg/m2 + Uromitexan 1200mg/m2

1g 8

i.v., Cisplatin 20mg/m2 i.v. 1-4 zi fiecare 3 s�pt.;

50mg 3

Paclitaxel 250mg/m2 i.v. perf. fiecare 3 s�pt.;

210mg 2

PC: Paclitaxel 175mg/m2 i.v. perf.,

210mg 2

17

Carboplatin AUC-7 perf. fiecare 3 s�pt.

150 4



1 Doxorubicin 30mg/m2 i.art. 1-3zi fiecare 3 s�pt.;

10mg 15


Cisplatin 150mg/m2 i.art. perf. fiecare 3 s�pt.;

50mg 6

Tumorile oaselor �icartilagiilor memrelor �i aleoaselor de alte loca-liz�ri

Glucoza N1 Metotrexat 7-10g/m2 500mg 30

Ureea N1 i.v. perf. + Acid folinic 15mg/m2 per os fiecare 6 ore N12 fiecare 2s�pt.;

30mg 12

Creatinina N1 Ifosfamid 2g/m2 i.v. perf. + Uromitexan 2g/m2 i.v. 1-5zi fiecare 3 s�pt.;

1g 15

Bilirubina N1 CAP: Ciclofosfan 200mg 5

Proteina total� N1 600mg/m2 i.v., Doxorubicin 40mg/m2

10mg 10

Albumina N1 i.v., Cisplatin 100mg/m2 50mg 4

ALT N1 i.v. perf. 1zi fiecare 3 s�pt.;

AST N1 DC: Doxorubicin 10mg 5

12

18

Fosfataza alcalin� N1 25mg/m2 i.v. 1-zi, Cisplatin 100mg/m2 i.v.

R-grafia pulmonar� perf. 1zi fiecare 3 s�pt.; 50mg 4

N1 IE: Ifosfamid 3g/m2 i.v. 1g 20

perf. + Uromitexan 3g/m2 i.v. 1-4zi, Etoposid 75mg/m2 i.v.

100mg 6

perf. 1-4zi fiecare 3 s�pt.;



CE: Carboplatin 150mg 8

Scintigrafia oaselor N1 150mg/m2 i.v. perf. 1-4zi, Etoposid 150mg/m2

100mg 12


i.v. perf. 1-4 zi fiecare 3 s�pt.;

R-grafia pulmonar� ACOP+Pt: Doxorubicin 40mg/m2

10mg 10

N1 i.v. 1zi, Ciclofosfan 200mg 5

600mg/m2 i.v. 1zi, Vincristin 2mg i.v. 1zi,

1mg 2


perf. 4zi, Prednizolon 5mg 16

1mg/kg per os 1-5 zi, fiecare 3-4 s�pt.

19

IE+VAC: Ifosfamid 1g 15

1,8g/m2 i.v. perf. + Uromitexan 1,8g/m2 i.v. 1-5zi, Etoposid

100mg 10

100mg/m2 i.v. perf.1-5zi se alterneaz� fiecare 3 s�pt. cu Vincristin

1,5mg/m2 i.v. 1zi, Doxorubicin 75mg/m2

1mg 2

i.v. 1zi, Ciclofosfan 10mg 15

1200mg/m2 i.v. 1zi. 200mg 10



1 Dacarbazin 250mg/m2 i.v. 1-5zi sau 800-1000mg/m2 i.v. perf. fiecare 3-4 s�pt.;

200mg 10


DI: Dacarbazin1000mg/m2 200mg 10

Melanomul malign Glucoza N1 i.v. perf. 1zi, Interferon alfa 5mlnUI/m2 s.c. 2-7zi fiecare 3-4 s�pt;

3mlnUI 18

Ureea N1 Dartmouth: Cisplatin 25mg/m2 i.v. perf. 1-3zi,

50mg 3

Creatinina N1 BCNU 150mg/m2 i.v. 150mg 2

Bilirubina N1 1zi, Dacarbazin 220mg/m2

i.v. 1-3zi fiecare 3s�pt, 200mg 6

12

20

Proteina total� N1 Tamoxifen 40mg per os zilnic îndelungat;

20mg 60

Albumina N1 CVD: Dacarbazin 800mg/m2


ALT N1 Vinblastin 1,6mg/m2 i.v. 5mg 3

AST N1 1-5zi, Cisplatin 20mg/m2 i.v. perf. 2-5zi fiecare 3 s�pt.;

50mg 3

Fosfataza alcalin� N1 PVB: Vinblastin 6mg/m2 i.v. 1, 2zi,

5mg 4

Bleomicin 15mg/m2 i.v. 15mg 10

1-5zi, Cisplatin 100mg/m2


R-grafia pulmonar� Chemoimmunoterapy: 20mg 60

N1 Tamoxifen 100mg/m2 1- 20mg 120

5zi, apoi 40mg zilnic,

Dacarbazin 1000mg/m2 200mg 10



i.v. perf. 6zi, Cisplatin 100mg/m2 i.v. perf . 7zi,

50mg 4


Interferon alfa 5mlnUI/m2

s.c. 8-13zi fiecare 3-4 s�pt.;3mlnUI 18

21

R-grafia pulmonar� N1 Biochemotherapy:

Dacarbazin 250mg/m2 200mg 6

i.v. 1-3zi, Cisplatin 25mg/m2

i.v. perf. 1-3zi, 50mg 3

Interferon alfa 5mlnUI/m2

s.c. 6,8,10, 3mlnUI 15

13,15zi, Interleukin-2 18mlnUI/m2 i.v. perf. 6-10, 13-15zi fiecare 4s�pt.;

18mlnUI 16

Temozolomide 200mg/m2

per os 1-5zi fiecare 4 s�pt.;200mg 10

Fotemustine 100mg/m2 i.v. perf. 1, 8, 15zi fiecare 3 s�pt.

200mg 3



1 Cisplatin 20mg/m2 i.v. perf. 1-5zi, fiecare 3 s�pt.;

50mg 4

Tumorile maligne ale pielii Analiza general� a urinei N1

Bleomicin 15mg i.v. 1-5zi, fiecare 3s�pt.;

15mg 5

Glucoza N1 CF: Cisplatin 100mg/m2 i.v. perf. 1zi,

50mg 4

Ureea N1 5Fluoruracil 750mg i.v. 1-5zi fiecare 3-4 s�pt.;

250mg 15

8

22

Creatinina N1 EP: Cisplatin 100mg/m2 i.v. perf. 1zi, Etoposid

50mg 4

Bilirubina N1 100mg/m2 1, 2, 3zi fiecare 3 s�pt.;

100mg 6

Proteina total� N1 PB: Cisplatin 100mg/m2 i.v. perf. 1zi, Bleomicin

50mg 4

Albumina N1 15mg i.v. 1-5zi, fiecare 3s�pt.;

15mg 5

ALT N1 PM: Cisplatin 100mg/m2 i.v. perf. 1zi,

50mg 4

AST N1 Metotrexat 40mg/m2 i.v. 1zi, fiecare 3-4s�pt.

10mg 8

Fosfataza alcalin� N1

R-grafia pulmonar�

N1b) medicina specializat� de laborator




N1C45 a) medicina


1 Doxorubicin 75 mg/m2 i.v. fiecare 3s�pt.;

10mg 15 10

23


Epirubicin 110mg/m2 i.v. fiecare 3 s�pt.;

10mg 20

Mezotelio-mul pleurei Glucoza N1 AP: Doxorubicin 10mg 10

Ureea N1 60mg/m2 i.v., Cisplatin 60mg/m2 i.v. perf. 1zi fiecare 3s�pt.;

50mg 2

Creatinina N1 GC: Gemcitabin 1000mg/m2

i.v. perf. 1, 1g 6

Bilirubina N1 8, 15zi, Cisplatin 100mg/m2



Albumina N1









1 Interferon alfa 3mlnUI s.c. 1-10zi fiecare 3s�pt.;

3mlnUI 10 10

24


Vincristin 1mg/m2 i.v. o dat� în s�pt., îndelungat;

1mg 8

Sarcomul Capo�i Glucoza N1 Vinblastin 5mg/m2 i.v. o dat� în s�pt., îndelungat;

5mg 8

Ureea N1 Etoposid 100mg/m2 i.v. perf. 1-5zi, fiecare 3s�pt.;

100mg 10

Creatinina N1 Doxorubicin 60mg/m2 i.v. fiecare 3s�pt.;

10mg 10

Bilirubina N1 Bleomicin 15mg i.v. 1-5zi, fiecare 3s�pt.;

15mg 5

Proteina total� N1 ABV: Doxorubicin 10mg 10

Albumina N1 40mg/m2, Bleomicin 15mg 2

ALT N1 15mg/m2, Vinblastin 6mg/m2

i.v. fiecare 3 s�pt.5mg 2

AST N1 ABO: Doxorubicin 150mg 5

Fosfataza alcalin� N1 20mg/m2, Bleomicin 15mg 1

R-grafia pulmonar� 10mg/m2, Vincristin 2mg i.v. fiecare 2 s�pt.

1mg 2

N1 AM: Doxorubicin 10mg 10

40mg/m2, Metotrexat 40mg/m2 i.v. fiecare 3 s�pt.

50mg 2

25





N1C50 a) medicina


1 Hormonoterapie:


Tamoxifen 20mg per os zilnic îndelungat;

20mg 90

Cancerul glandei mamare Glucoza N1 Toremifen 60mg per os zilnic îndelungat;

60mg 90

Ureea N1 Anastrozol 1mg per os zilnic îndelungat;

1mg 28

Creatinina N1 Exemestan 25mg per os zilnic îndelungat;

25mg 30

Bilirubina N1 Megestrol acetat 160mg per os zilnic îndelungat;

40mg 120

Proteina total� N1 Depo-provera 1000mg i.m. 2 ori pe s�pt. îndelungat;

500mg 20

Albumina N1 Proloteston1ml i.m. o dat� în 2 s�pt., îndelungat;

1ml 6

10

26

ALT N1 Goserelin 3,6mg s.c. implant fiecare 4 s�pt.

3,6mg 3

AST N1 Chimioterapie:

Fosfataza alcalin� N1 CMF: Ciclofosfan 100mg/m2

per os 1-14zi, 200mg 14

R-grafia pulmonar� Metotrexat 40mg/m2 i.v. 1, 8zi, 5-Fluoruracil

50mg 3

N1 600mg/m2 i.v. 1, 8zi, fiecare 4 s�pt.;

250mg 8

CMF1: Ciclofosfan 200mg 10



600mg/m2, Metotrexat 50mg 3

Scintigrafia oaselor N1 40mg/m2, 5-Fluoruracil 250mg 8

Receptorii hormonali 600mg/m2 i.v. 1, 8zi, fiecare 4 s�pt.;

HER-2neu AC: Doxorubicin 60mg/m2, Ciclofosfan

10mg 10


600mg/m2 i.v. fiecare 3 s�pt.; 200mg 5

R-grafia pulmonar� EC: Epirubicin 90mg/m2, Ciclofosfan

10mg 15

N1 600mg/m2 i.v. fiecare 3 s�pt.; 200mg 5

27

FAC: 5-Fluoruracil 600mg/m2 ,

250 4


Ciclofosfan 600mg/m2 i.v. fiecare 3 s�pt.;

200mg 5

FEC: 5-Fluoruracil 250mg 4

500mg/m2, Epirubicin 10mg 15

100mg/m2, Ciclofosfan 200mg 5

500mg/m2 i.v. fiecare 3 s�pt.;

CAF: Ciclofosfan 100mg/m2

per os 1-14zi;200mg 14

Doxorubicin 30mg/m2 i.v. 1, 8zi,

10mg 10

5-Fluouracil 500mg/m2 i.v. 1,8zi fiecare 4 s�pt.;

250mg 8

CAF1: Ciclofosfan 200mg 10

600mg/m2 i.v. 1, 8zi; Doxorubicin 30mg/m2

50mg 2

i.v. 1, 8zi, 5-Fluouracil 500mg/m2 i.v. 1, 8zi fiecare 3-4 s�pt.;

250mg 8

DA: Doxorubicin 10mg 10

28

50mg/m2 i.v., Docetaxel 75mg/m2 i.v. perf.

80mg 2

fiecare 3 s�pt.;

PA: Doxorubicin 10mg 10

50mg/m2 i.v., Paclitaxel 210mg 2

200mg/m2 i.v. perf. fiecare 3 s�pt.;

CAP: Ciclofosfan 200mg 5

500mg/m2 i.v., Doxorubicin 50mg/m2

10mg 10

i.v., Cisplatin 100mg/m2 i.v. perf. 1zi fiecare 3

s�pt.; 50mg 4Capecitabine

2500mg/m2 per os 14 zile, fiecare 3 s�pt.;

500mg 120

Trastuzumab 4-2mg/kg

i.v. perf. fiecare s�pt.; 150mg 2

PH: Paclitaxel 200mg/m2 i.v. perf.

210mg 2

fiecare 3 s�pt., Trastuzumab 4-2mg/kg

150mg 2

i.v. perf. fiecare s�pt.




50mg 4 8

29



250mg 15

Cancerul vulvei, cancerulvaginului, colului uterin

Glucoza N1 Ifosfamid 1500mg/m2 i.v. perf. + Uromitexan 1500mg/m2 i.v. 1-5zi fiecare 3 s�pt.;

1g 15

Ureea N1 CI: Cisplatin 100mg/m2 50mg 4

Creatinina N1 i.v. perf., Ifosfamid 5000mg/m2 perf. + Uromitexan 5000mg/m2 i.v. fiecare 3 s�pt.;

1g 10

Bilirubina N1 BIP: Bleomicin 15mg/m2 i.v. 1zi,

15mg 2

Proteina total� N1 Cisplatin 50mg/m2 i.v. 50mg 2

Albumina N1 perf. 1zi, Ifosfamid 1000mg/m2 i.v. perf. + Uromitexan 1000mg/m2 i.v. 1-5zi fiecare 3 s�pt.;

1g 10

ALT N1 PC: Paclitaxel 135mg/m2 i.v. perf. 1zi,

210mg 1

AST N1 Cisplatin 75mg/m2 i.v. perf. 2zi fiecare 3s�pt.;

50mg 3

Fosfataza alcalin� N1 TIP: Paclitaxel 135mg/m2

i.v. perf.1zi, 210mg 1

R-grafia pulmonar� Cisplatin 75mg/m2 i.v. 50mg 3

30

N1 perf. 2zi, Ifosfamid 5000mg/m2 perf. + Uromitexan 5000mg/m2 i.v. perf. 2zi fiecare 3 s�pt.;

1g 10

PVB: Vinblastin 6mg/m2 i.v. 1, 2zi,

5mg 4



Bleomicin 15mg/m2 i.v. 15mg 10




R-grafia pulmonar� CAP: Ciclofosfan 600mg/m2

i.v., 200mg 2

N1 Doxorubicin 50mg/m2 10mg 10

i.v., Cisplatin 100mg/m2 i.v. perf. 1zi fiecare 3 s�pt.

50mg 4

MAP: Metotrexat 40mg/m2

i.v., 50mg 2


i.v., Cisplatin 50mg/m2 i.v. perf.fiecare 3 s�pt.

50mg 2

31



1 Hormonoterapie:


Medroxiprogesteron acetat 800mg per os îndelungat;

400mg 120

Cancerul corpului uterin Glucoza N1 Depo-provera 1000mg i.m. 4s�pt., apoi 2 ori pe s�pt. îndelungat;

500mg 70

Ureea N1 Megestrol acetat 160mg per os zilnic îndelungat;

40mg 240

Creatinina N1 Tamoxifen 40mg zilnic, îndelungat;

20mg 180

Bilirubina N1 Chimioterapie:

Proteina total� N1 AP: Doxorubicin 60mg/m2

i.v.,10mg 10

Albumina N1 Cisplatin 60mg/m2 i.v. perf. 1zi fiecare 3 s�pt.;

50mg 2

ALT N1 CAP: Ciclofosfan 600mg/m2

i.v., 200mg 5

AST N1 Doxorubicin 50mg/m2 i.v., 10mg 10

Fosfataza alcalin� N1 Cisplatin 100mg/m2 i.v. perf. 1zi fiecare 3 s�pt.

50mg 4

R-grafia pulmonar� CAF1: Ciclofosfan

400mg/m2 i.v. 1, 8zi;

200mg 8

10

32

N1 Doxorubicin 30mg/m2 10mg 10

i.v. 1, 8zi, 5-Fluouracil 400mg/m2 i.v. 1, 8zi fiecare 3-4 s�pt.;

250mg 6



PAC: Doxorubicin 10mg 10

Receptorii hormonali 45mg/m2 i.v., Paclitaxel 135mg/m2 i.v. perf.,

210mg 1


Cisplatin 60mg/m2 i.v. perf. 1zi fiecare 3 s�pt.

50mg 2


N1



1 TP: Paclitaxel 135mg/m2 i.v. perf.,

210mg 1


Cisplatin 75mg/m2 i.v. perf. fiecare 3 s�pt.;

50mg 3

Cancerul ovarian Glucoza N1 CP: Cisplatin 100mg/m2 i.v. perf., Ciclofosfan

50mg 4

Ureea N1 750mg/m2 i.v. fiecare 3 s�pt.; 200mg 7

Creatinina N1 CAP: Ciclofosfan 600mg/m2

i.v., 200mg 2


8

33


50mg 4

Albumina N1 CI: Cisplatin 60mg/m2 50mg 2

ALT N1 i.v. perf., Ifosfamid 4000mg/m2 perf. + Uromitexan 4000mg/m2 i.v. fiecare 3 s�pt.;

1g 8

AST N1 DC: Docetaxel 75mg/m2 i.v. perf., Cisplatin

80mg 2

Fosfataza alcalin� N1 75mg/m2 i.v. perf. fiecare 3s�pt.;

50mg 3

R-grafia pulmonar� GC: Gemcitabine 1000mg/m2 i.v. perf. 1,

1g 6

N1 8, 15zi, Cisplatin 75mg/m2

i.v. perf. 1zi fiecare 3-4 s�pt.;50mg 3

Etoposid 100mg/m2 per os 1-14zi fiecare 3-4 s�pt.

100mg 28



Ca-125 EP: Cisplatin 20mg/m2 50mg 4

34


i.v. perf., Etoposid 100mg/m2

i.v. perf. 1-5zi fiecare 3s�pt.;100mg 10

R-grafia pulmonar� BEP: Cisplatin 20mg/m2 i.v. perf. 1-5zi,

50mg 4

N1 Etoposid 100mg/m2 i.v. perf. 1-5zi,

100mg 10

Bleomicin 15mg/m2 i.v. 1, 3, 5zi fiecare 3 s�pt.;

15mg 6

Tumorile germinoge-neovariene

+ Alfa-fetoproteina Horiocarcinogoni-na

PVB: Vinblastin 3mg/m2 i.v. 1, 2zi,

5mg 2

Lactatdehidroge-naza Bleomicin 10mg/m2 i.v. 15mg 3



VI: Etoposid 100mg/m2 i.v. perf. 1-3zi,

100mg 6

Ifosfamid 1500mg/m2 i.v. perf. + Uromitexan 1500mg/m2 i.v. 1-5zi fiecare 3 s�pt.;

1g 15

VPIC: Etoposid 100mg/m2

i.v. perf. 1-100mg 6

35

3zi, Ifosfamid 1500mg/m2

i.v. perf. + Uromitexan 1500mg/m2

1g 15

i.v. 1-5zi, Cisplatin 20mg/m2

i.v. perf. 1-5zi fiecare 3 s�pt.50mg 4



1 Metotrexat 0,4mg/kg i.m. 1-5zi fiecare 2s�pt.;

10mg 3


Dactinomicin 300mkg/m2

i.v. 1-5zi fiecare 2 s�pt.;500mkg 5

Maladia trofoblastic� Glucoza N1 Etoposid 100mg/m2 i.v. 1-5zi fiecare 2 s�pt.;

100mg 10

Ureea N1 CAM: Ciclofosfan 400mg/m2 i.v.,

200mg 4

Creatinina N1 Doxorubicin 30mg/m2 10mg 5

Bilirubina N1 i.v., Metotrexat 20mg/m2 i.v. fiecare 3 s�pt.;

5mg 1

Proteina total� N1 EP: Cisplatin 20mg/m2 50mg 4

Albumina N1 i.v. perf., Etoposid 100mg/m2


ALT N1 PVB: Vinblastin 3mg/m2 i.v. 1, 2zi,

5mg 2

8

36

AST N1 Bleomicin 10mg/m2 i.v. 15mg 3

Fosfataza alcalin� N1 1-3zi, Cisplatin 100mg/m2





Horiocarcinogonina


R-grafia pulmonar�N1



1 BV: Bleomicin 15mg i.v. 3ori pe s�pt. N9,

15mg 9


Vincristin 2mg i.v 1, 8, 15zi fiecare 4s�pt.;

1mg 6

Cancerul penisului Glucoza N1 Metotrexat 30mg/m2 i.v. 1, 8, 15zi fiecare 4 s�pt.;

50mg 3

Ureea N1 AMB: Doxorubicin 50mg/m2

i.v. 1zi, 10mg 10

Creatinina N1 Metotrexat 20mg/m2 i.v. 10mg 2

12

37

Bilirubina N1 1, 8,15zi, Bleomicin 15mg/m2 i.v. 1, 8, 15zi fiecare 4 s�pt.;

15mg 6

Proteina total� N1 CMB: Cisplatin 75mg/m2


Albumina N1 Metotrexat 25mg/m2 i.v. 50mg 2

ALT N1 1, 8zi, Bleomicin 10mg/m2

i.v. 1, 8zi fiecare 3 s�pt.;15 2

AST N1 PF: Cisplatin 100mg/m2 i.v. perf. 1zi, 5-

50mg 4

Fosfataza alcalin� N1 Fluoruracil 500mg/m2 i.v. 1-4zi, fiecare 3s�pt.

250mg 16






N1C61 a) medicina

primar�Analiza general� a sîngelui + trombo-cite N1

1 Hormonoterapie: 12

38


Goserelin 3,6mg s.c. implantfiecare lun�;

3,6mg 1

Cancerul prostatei Glucoza N1 Androcur 200mg per oszilnic îndelungat;

50mg 150

Ureea N1 Flutamid 750mg per oszilnic îndelungat;

250mg 100

Creatinina N1 Fosfestrol 300-1200mg i.v.zilnic îndelungat;

300mg 100

Bilirubina N1 Estracit 450mg i.v. zilnic 3s�pt., apoi 2 ori pe s�pt.îndelungat;

450mg 21

Proteina total� N1 Megestrol acetat 40-160mgper os zilnic îndelungat.

40mg 120

Albumina N1 Chimioterapie:

ALT N1 AP: Doxorubicin 10mg 10

AST N1 60mg/m2 i.v., Cisplatin60mg/m2 i.v. perf. fiecare 3-4s�pt.;

50mg 2

Fosfataza alcalin� N1 CAP: Ciclofosfan 600mg/m2

i.v., 200mg 5

R-grafia pulmonar� Doxorubicin 50mg/m2 10mg 10

N1 i.v., Cisplatin 100mg/m2 i.v. perf. 1zi fiecare 3 s�pt.;

50mg 4

39

AC: Doxorubicin 30mg/m2

i.v. 1, 8zi, 10mg 10


Ulrasonografia or-ganelor interne N1

Ciclofosfan 100mg/m2 per os1-14zi fiecare 4 s�pt.;

100mg 28

Scintigrafia oaselor N1 D+EMP: Docetaxel70mg/m2 i.v. perf . 2zi,Estramustin 280mg per os 1-5zi fiecare 3 s�pt.;

80mg 2

PSA Mitoxantron 12mg/m2 i.v. odat� în 3 s�pt.,

5mg 4


Prednizolon 10mg zilnicîndelungat.

5mg 100




1 EP: Cisplatin 20mg/m2 50mg 4


i.v. perf., Etoposid 100mg/m2


Cancerul testiculului Glucoza N1 BEP: Cisplatin 20mg/m2 i.v. perf. 1-5zi,

50mg 4

8

40

Ureea N1 Etoposid 100mg/m2 i.v. perf. 1-5zi, Bleomicin

100mg 10

Creatinina N1 15mg/m2 i.v. 1, 3, 5zi fiecare 3 s�pt.;

15mg 6

Bilirubina N1 VAB-6: Vinblastin 6mg/m2

i.v. 1zi, 5mg 2

Proteina total� N1 Dactinomicin 1mg/m2 i.v. perf. 1zi,

0,5mg 4

Albumina N1 Ciclofosfan 600mg/m2 200mg 5

ALT N1 i.v. 1zi, Bleomicin 30mg i.v. 1-4zi,

15mg 8

AST N1 Cisplatin 120mg/m2 i.v. perf. 4zi fiecare 3s�pt.;

50mg 4

Fosfataza alcalin� N1 PVB: Vinblastin 3mg/m2 i.v. 1, 2zi,

5mg 2

R-grafia pulmonar� Bleomicin 15mg/m2 i.v. 15mg 6

N1 1-3zi, Cisplatin 100mg/m2


VIP: Cisplatin 20mg/m2 i.v. perf., Etoposid

50mg 4



75mg/m2 i.v. perf., 100mg 10

41

Alfa-fetoproteina Ifosfamid 1200mg/m2 i.v. perf. + Uromitexan 1200mg/m2 i.v. 1-5zi fiecare 3s�pt.;

1g 10

Horiocarcinogoni-na VeIP: Vinblastin 0,11mg/kg i.v. 1, 2zi,

5mg 2

LDH Ifosfamid 1200mg/m2 i.v. perf. + Uromitexan 1200mg/m2 i.v. 1-5zi,

1g 10


Cisplatin 20mg/m2 i.v. perf. 1-5zi fiecare 3 s�pt.;

50mg 4

R-grafia pulmonar� T-BEP: Paclitaxel 135mg/m2


N1 Cisplatin 20mg/m2 i.v. 50mg 4

perf. 1-5zi, Etoposid 100mg/m2 i.v. perf. 1-

100mg 10

5zi, Bleomicin 15mg/m2 i.v. 1, 3, 5zi fiecare 3 s�pt.

15mg 6



1 Interferon alfa 3mlnUI s.c. 10 zile fiecare 3 s�pt.;

3mlnUI 10


Interleukin-2 9mlnUI s.c. 6 zile fiecare 3s�pt.;

18mlnUI 3

14

42

Cancerul renal Glucoza N1 Depo-provera 1000mg i.m. 2 ori pe sâpt. îndelungat;

500mg 25

Ureea N1 Tamoxifen 40-100mg zilnic îndelungat;

20mg 150

Creatinina N1 VFI: Vinblastin 6mg/m2 i.v. 1, 8 zi, 5-Fluoruracil

5mg 4

Bilirubina N1 500mg/m2 i.v. 1, 3, 5, 8, 10zi, Interferon alfa

250mg 15

Proteina total� N1 6mlnUI s.c. 11-16zi. 3mlnUI 12

Albumina N1


R-grafia pulmonar�N1



Scintigrafia oaselor N1



N1C65, C66, C67 a) medicina


1 MVAC: Metotrexat 30mg/m2 i.v. 1, 15, 22zi,

50mg 2 12

43


Vinblastin 3mg/m2 i.v. 2, 15, 22zi, Doxorubicin

5mg 3

Cancerul bazinetului renal,ureterului, vezicii urinare

Glucoza N1 30mg/m2 i.v. 2zi, 10mg 5

Ureea N1 Cisplatin 70mg/m2 i.v. perf. 2zi fiecare 4s�pt.;

50mg 3

Creatinina N1 MVEC: acela�i regim cu înlocuirea Doxorubicinei pe Epirubicin� 50mg/m2;

10mg 10

Bilirubina N1 MVAC1: Metotrexat 50mg 2

Proteina total� N1 30mg/m2 i.v. 1, 8zi, Vinblastin 6mg/m2 i.v.

5mg 4

Albumina N1 1, 8zi, Doxorubicin 10mg 10

ALT N1 30mg/m2 i.v. 1, 8zi, Cisplatin 70mg/m2 i.v.

50mg 3

AST N1 perf. 3zi fiecare 4s�pt.;

Fosfataza alcalin� N1 CMV: Cisplatin 100mg/m2

i.v. perf. 2zi, Metotrexat 30mg/m2 i.v.

50mg 4

R-grafia pulmonar� 1, 8zi, Vinblastin 50mg 2

N1 4mg/m2 i.v. 1, 8zi fiecare 3s�pt.

5mg 4

CAP: Ciclofosfan 200mg 4

44



400mg/m2 i.v., Doxorubicin 40mg/m2

10mg 10


i.v., Cisplatin 70mg/m2 50mg 3

R-grafia pulmonar� i.v. perf. 1zi fiecare 3 s�pt.;

N1 CG: Cisplatin 60mg/m2 50mg 2

i.v. perf. 1zi, Gemcitabin 1000mg/m2

1g 4

1, 8 zi fiecare 4 s�pt.;

TC: Paclitaxel 210 1

135mg/m2 i.v. perf., Cisplatin 75mg/m2 i.v.

50mg 3

perf. fiecare 3 s�pt.

C70,C71, C72 a) medicina primar�


1 Lomustin 80-120mg/m2 per os o dat� în6 s�pt.;

20mg 8


Temozolomid 150mg/m2 per os 1-5zi fiecare 4s�pt.;

150mg 10

Tumorile meningeale,cerebrale �i ale m�duveispinale

Glucoza N1 PCV: Lomustin 20mg 8

10

45

Ureea N1 100mg/m2 per os 1zi, Procarbazin 100mg/m2

50mg 50

Creatinina N1 per os 1-10zi, Vincristin 1mg 2

Bilirubina N1 1,5mg/m2 i.v. 1zi fiecare 6 s�pt.;

Proteina total� N1 CDV: Lomustin 100mg/m2

per os 1zi, Doxorubicin 30mg/m2

20mg 8

Albumina N1 i.v. 2, 9zi, Vincristin 10mg 10

ALT N1 2mg i.v. 2, 9zi fiecare 6 s�pt.; 1mg 4

AST N1 CAP: Ciclofosfan 500mg/m2

i.v., Doxorubicin 50mg/m2

200mg 5

Fosfataza alcalin� N1 i.v., Cisplatin 50mg/m2 10mg 10

R-grafia pulmonar� i.v. perf. 1zi fiecare 3 s�pt.; 50mg 2

N1 DC: Dacarbazin 250mg/m2, 200mg 10

Carboplatin100mg/m2 i.v. 1-4zi fiecare 3s�pt.

150mg 6



46

Tomografia computerizat�



N1C73 a) medicina


1 Doxorubicin 75mg/m2 i.v. fiecare 3s�pt.;

10mg 15


Epirubicin 100mg/m2 i.v. perf. fiecare 3s�pt.;

10mg 18

Cancerul glandei tiroide Glucoza N1 AP: Doxorubicin 10mg 10

Ureea N1 60mg/m2 i.v., Cisplatin 40mg/m2 i.v. perf. fiecare 3s�pt.;

50mg 2

Creatinina N1 ABC: Doxorubicin 60mg/m2

i.v. 1zi, 10mg 10

Bilirubina N1 Bleomicin 15mg i.v. 1- 15mg 4

Proteina total� N1 4zi, Cisplatin 100mg/m2 i.v. perf. 4zi fiecare 3 s�pt.;

50mg 4

Albumina N1 ABO: Doxorubicin 70mg/m2

i.v. 1zi, 10mg 15

ALT N1 Bleomicin 15mg i.v. 1- 15mg 5

AST N1 5zi, Vincristin 2mg i.v. 1, 8 zi fiecare 3 s�pt.;

1mg 4

8

47

Fosfataza alcalin� N1 VAC: Vincristin 1,4mg 1mg 2

R-grafia pulmonar� i.v., Doxorubicin 60mg/m2

i.v., 10mg 10

N1 Ciclofosfan 1000mg/m2 i.v. fiecare 3 s�pt.;

200mg 10

CVD: Ciclofosfan 750mg/m2

i.v. 1zi, 200mg 7



Vincristin 1,4mg/m2 i.v. 1mg 2


1zi, Dacarbazin 600mg/m2

i.v. 1, 2 zi fiecare 3-4s�pt.200mg 10


N1C74, C75 a) medicina


1 Hloditan 8g per os zilnicîndelungat;


CEB: Cisplatin 40mg/m2 i.v. perf.,

50mg 2

Tumorile suprarenale, aaltor glande endocrine

Glucoza N1 Etoposid 100mg/m2 i.v., 100mg 2

Ureea N1 Bleomicin 30mg i.v. fiecare 4 s�pt.;

15mg 2

Creatinina N1 CAP: Ciclofosfan 600mg/m2

i.v., 200mg 5

8

48



50mg 2

Albumina N1 CVD: Ciclofosfan 200mg 7

ALT N1 750mg/m2, Vincristin 1mg 2

AST N1 1,4mg/m2, Dacarbazin 600mg/m2 i.v. fiecare 3 s�pt;

200mg 5

Fosfataza alcalin� N1 AP: Doxorubicin 10mg 10

R-grafia pulmonar� 50mg/m2 i.v., Cisplatin 50mg/m2 i.v. perf. fiecare 3s�pt.;

50mg 2

N1 COAP: Ciclofosfan 500mg/m2 i.v. 1zi,

200mg 5

Vincristin 1mg/m2 i.v. 1mg 4



1, 8zi, Doxorubicin 30mg/m2

i.v. 1zi, 10mg 5

Cateholaminele Cisplatin 100mg/m2 i.v. perf. 2zi fiecare 4 s�pt.;

50mg 4


Interferon alfa 3mlnUI s.c. 10zile la 3 s�pt.;

3mlnUI 10

49

R-grafia pulmonar� EP: Cisplatin 100mg/m2 i.v. perf. 1zi, Etoposid

50mg 4

N1 100mg/m2 i.v. perf. 1-5zi fiecare 3s�pt.;

100mg 10

CAF: 5-Fluoruracil 400mg/m2 i.v. 1, 8 zi, Doxorubicin 30mg/m2

250mg 8

i.v. 1, 8zi, Ciclofosfan 10mg 10

100mg/m2 per os 1-14zi fiecare 4 s�pt.

200mg 14

C77, C78, C79, C80 a) medicina primar�


1 CAF: 5-Fluoruracil 400mg/m2 i.v. 1, 8 zi,

250mg 8



Schimb�ri secundare în g/l,organele respira-torii,digestive �i alte f�r� sediuprimar pre-cizat

Glucoza N1 i.v. 1, 8zi, Ciclofosfan 100mg/m2 per os 1-14zi fiecare 4 s�pt.;

200mg 14

Ureea N1 VAC: Vincristin 1mg 2

Creatinina N1 1,4mg/m2, Doxorubicin 10mg 10

Bilirubina N1 50mg/m2, Ciclofosfan 500mg/m2 i.v. fiecare 3s�pt.;

200mg 5

12

50

Proteina total� N1 EP: Cisplatin 100mg/m2 i.v. perf. 1zi, Etoposid

50mg 4

Albumina N1 100mg/m2 i.v. perf. 1-5zi fiecare 3s�pt.;

100mg 10

ALT N1 BEP: Cisplatin 20mg/m2 i.v. perf. 1-5zi,

50mg 4

AST N1 Etoposid 100mg/m2 i.v. perf. 1-5zi,

100mg 10

Fosfataza alcalin� N1 Bleomicin 15mg/m2 i.v. 1, 3, 5zi fiecare 3 s�pt.;

15mg 6

R-grafia pulmonar� PVB: Vinblastin 5mg 2

N1 3mg/m2 i.v. 1, 2zi, Bleomicin 10mg/m2 i.v.

15mg 3

1-3zi, Cisplatin 50mg 4


Ulrasonografia or-ganelor interne N1

100mg/m2 i.v. perf. 4zi fiecare 3 s�pt.;


DC: Docetaxel 75mg/m2 80mg 2

R-grafia pulmonar� i.v. perf., Carboplatin 300mg/m2 i.v. perf.

150mg 4

N1 fiecare 3 s�pt.;

TFL: Paclitaxel 210mg 1

51

135mg/m2 i.v. perf. 1zi, 5-Fluoruracil 500mg/m2

250mg 12

i.v. 1-3zi, Leucovorin 30mg 10

30mg/m2 i.v. 1-3zi fiecare 4 s�pt.;

ACOP+Pt: Doxorubicin 40mg/m2

10mg 10

i.v. 1zi, Ciclofosfan 200mg 5

600mg/m2 i.v. 1zi, Vincristin 2mg i.v. 1zi,

1mg 2


perf. 4zi, Prednizolon 5mg 100

1mg/kg per os 1-5 zi, fiecare 3-4 s�pt.

52

standarde medicale de diagnostic i tratament …old.ms.md/_files/1951-6.chimioterapie.pdf ·...

Documents