tb in india msf missions perspectives_joanna & camillo

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  • 7/28/2019 TB in India MSF missions perspectives_Joanna & Camillo

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    TB in India

    MSF Missions perspectives

    MSF TB workshop Delhi 2013By Joanna Ladomirska and Camilo Gomez

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    TB/DRTB in India epidemiological highlights (1)

    2.000.000 new TB cases every year with 300.000 deaths

    100.000 new MDRTB cases estimated by WHO (wentdown to 66.000 ?)

    MDRTB official prevalence 4,1% (3% NC 17% RC)

    Other data on MDRTB: Chandigarh : 17,4% (9,9% NC 27,6% RC)

    Mumbai: 24% NC and 41% RC (2009)

    Sweiri TB hospital: 14% MDR, 60% pre-XDR, 20% XDR, 6% XXDR

    Hinduja lab: 70,1% FQ resistance

    MSF OR first data: 21% with Rif resistance

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    DRTB epidemic not linked to HIV man made

    High burden

    Heterogeneity of the epidemiological context

    Amplification of resistance profiles ("MumbaiTDR 2012", clear trend)

    70% treated in private sector

    Dynamic context ...

    TB/DRTB in India epidemiological highlights (2)

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    DRTB in India government numbers

    Diagnosis: FLDST: 35 LPA, 10 LC - DST, 3 SLC - DST, 30

    GeneXperts SLDST: 3

    100.000 suspected screened, 16.800 diagnosed(> half in 2012)

    Treatment: 6000 MDRTB in 2012

    Plans: SLDST: 8 in 2012, 12 in 2014, 22 in 2015 In coming 5 years

    160.000 MDR treated, 4100 XDR 3.000.000 DST / year

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    TB in India MSF perspective (1)

    Magnitude of TB/DRTB epidemic in India

    Model of care

    Package of care (national protocols and their

    implementation / drugs / patient support)

    Prevention and IC

    Resources

    Regulatory and legal issues Advocacy mechanism

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    TB in India MSF perspective (2)

    Magnitude of TB/DRTB epidemic in India

    Government in denial

    No reliable data how to adapt a strategy?

    Surveys? Model of care

    dysfunctional public and unregulated private

    baseline context for all the rest discussions in avacuum

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    TB in India MSF perspective (3)

    Package of care national protocols and their implementation

    diagnosis GeneXpert role and SLDST availability ... possibilityto decentralized DST?, coverage / access

    intermittent treatment, no FDC, standardize not DST based

    approach for DR treatment, no mono and poly knowledge abortion access gaps in DOTS implementation, slow scaling up

    drugs quality issue in public and private

    government supply system availability of intermittent regimen drugs role of WHO

    patient support concept itself more service than patient oriented approach

    barriers to adherence not analyzed

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    TB in India MSF perspective (4)

    Prevention and IC very low awareness

    IC procedures?

    Resources

    money internal / external? HR

    Regulatory and legal issues gaps for CU, new drugs ...

    Advocacy mechanism epidemic not linked to HIV, need for different advocacyplatform

    government not taking into consideration internationalfindings has to be Indian

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    TB in India opportunities

    technical expertise research capacity strong civil society structure, legal frame for

    advocacy, media local production of drugs India international role => when the world

    speak about TB, world speak about India BRICs RIC with highest burden CAME and operations present louder

    advocacy?

    Fascinating context for MSF intervention ...

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    5 Projects:

    OCAChhattisgarh (MCHC)

    Manipur (HIV-MDR)

    OCBMUMBAI (HIV/DRTB)AP-CG (PHC)

    Nagaland (Hospital)

    + CAME in Delhi ...

    TB in MSFprojects inIndia (1)

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    TB in MSF projects in India (2)

    Integrated approach:

    Chhattisgarh OCA and OCB PHC in area affectedby conflict

    Nagaland OCB Primary and secondary health carefor neglected population

    Vertical approach:

    Mumbai OCB HIV/DRTB

    Manipur OCA HIV/DRTB

    Different level of government involvement /collaboration

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    TB in MSF projects Data DSTB

    Project 2012 Annual numbersof DSTB cases

    CG OCB 129CG OCA 99Manipur OCA 263Nagaland OCB 187Mumbai OCB 11Total 689

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    TB in MSF projects Data DRTB

    DRTBdiagnosed

    Accumulative

    MONO POLY MDR Pre

    XDR

    XDR XXDR Empir. TOTAL

    CG OCB 2 4 4 10

    CG OCA 2 7 9

    ManipurOCA

    4 1 29 10 3 47

    NagalandOCB

    4 1 12 4 1 22

    Mumbai OCB 9 8 40 41 16 4 35 153

    TOTAL 21 14 92 55 17 4 38 241

    * Mumbai currently: XXDR 7%, XDR 20%, PreXDR 26%, MDR 15%, Mono and Poly 8%, Empirical 24%

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    TB in MSF projectsDiverse contexts and challenges

    Mumbai: complicated resistance profiles co-morbidities, co-infections pediatrics psycho social aspects hospitalization of severe cases

    CG accessibility insecurity continuity of care community perception / cultural believes

    Nagaland severe cases and unusual presentations

    community perception / cultural believes remote area

    Manipur accessibility cross border patients HIV co-infection

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    TB in MSF projects - Components

    1. direct care (DS and DR TB)2. capacity building impact on partners

    through support3. advocacy / catalyze for change (including OR)

    impact of island of excellence versus advocacy frominside approaches

    central and state levels

    Those 3 components are present in vertical orintegrated approach, with different level ofactivities.

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    TB in MSF projects general aspects

    Operations versus advocacy objectives

    The way forward? Define MSF role in overall advocacy line Define MSF short and long terms objectives

    Intersectional and CAME coordination

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    Why this workshop?

    Complex context

    "campaigning in a vacuum (protocols, drugregistration)

    need for new approaches and specific support

    clarification of MSF position towards specificproblems to adapt advocacy strategy at

    mission level. Importance of India and its opportunities

    for MSF

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    THANK YOU!

    Let's discuss ...