the 5th international student seminar seminar... · 2014. 5. 27. · from the committee the 5th...
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Kyoto University 21st Century COE Program
COE Formation in Frontier Life Science by Unifying Interactions
The 5th International Student Seminar
"the active exchange of the young scientists’ research across borders and between fields”
27th February – 2nd March, 2007
Graduate School of Biostudies and Institute for Virus Research,
Kyoto University, Japan
From the Committee
The 5th International Student Seminar (5thISS) is the scientific seminar OF the students,
BY the students and FOR the students. This seminar is planned and held by the
graduate students themselves in the Graduate School of Biostudies and the Institute
for Virus Research, Kyoto University, Japan.
The concept of it is "the active exchange of the young scientists’ research across
borders and between fields”. Nowadays the studies in life science have progressed
rapidly, whereas split into various small fields. But for the future progress in life science
it should be important to know the results and the methods in all fields in life science
and to co-operate one field with different fields. So we have planed the seminar, in
which graduate students and postdoctoral fellows in the various fields of life science in
the world present and discuss their studies actively and know the latest studies in life
science. We hope that young scientists discuss the future of life science and establish
friendships through this seminar, and people who form friendships in the seminar will
become core members of top scientists to lead life science studies.
The 21st Century COE Program
The 5thISS Executive Committee
General Information
Date: 27th February – 2nd March 2007
Venue: Kyodai Kaikan and NeoII, Kyoto, Japan
Language: English
Executive Committee:
・ 橋本 康史 / Yasufumi Hashimoto (Nishida Lab.; Biostudies :The chair)
・ 千代田 将大 / Shota Chiyoda (Kohchi Lab.; Biostudies :The vice-chair)
・ 佐藤 太一 / Daichi Sato (Uemura Lab.; Biostudies :The vice-chair)
・ 稲葉 一寿 / Katsuhisa Inaba (Miura Lab.; IVR)
・ 今吉 格 / Itaru Imayoshi (Kageyama Lab.;IVR)
・ 黒木 俊介 / Shunsuke Kuroki (Yonehara Lab.; Biostudies)
・ 谷 泰史 / Yasushi Tani (Yamamoto Lab.; Biostudies)
・ 篠田 康彦 / Yasuhiko Shinoda (Koyanagi Lab.;IVR)
・ 室井 かおり / Kaori Muroi (Kato Lab.; Biostudies)
・ 鎧坂 将史 / Masafumi Yoroisaka (Kakizuka Lab.; Biostudies)
・ 伊藤 由梨 / Yuri Ito (Negishi Lab.; Biostudies)
・ 井戸 邦夫 / Kunio Ido (Sato Lab.; Biostudies)
・ 大塚 正太郎 / Shotaro Otsuka (Takeyasu Lab.; Biostudies)
・ 吉原 栄治 / Eiji Yoshihara (Yodoi Lab.;IVR)
*Biostudies: Graduate School of Biostudies *IVR: Institute for Virus Research
Web site: http://www.lif.kyoto-u.ac.jp/coe5th/
Schedule:
27th February: Host Laboratory Seminars
28th February-1st March: Symposium (Kyodai Kaikan)
2nd March: Group Seminar (NeoII)
*This seminar is supported by the 21st Century Center of Excellence (COE) Program, “COE
formation in frontier life sciences by unifying interactions”, of the Ministry of Education,
Culture, Sports, Science and Technology to Graduate School of Biostudies and Institute for
Virus Research, Kyoto University, Japan.
Program of the 5thISS
27th February 28th February 1st March 2nd March
8:00 Registoration
Opening Remarks9:00 Oral Session E
(9:00-10:15)Oral Session A10:00 Group Seminar
11:00 Oral Session FOral Session B (10:30~12:10)(11:05-12:20)
12:00
Lunchtime Lunchtime13:00 (12:20-13:50) (12:10-13:50)
14:00 Host Laboratory Oral Session GSeminars Oral Session C (13:50-15:05)
(13:50-15:30)15:00
Oral Session H16:00 Oral Session D (15:35~17:15) Free Discussion(16:00-17:15)
17:00
Poster Session Poster Session(17:30-19:00) (17:30-19:00)18:00
A-1~A-43 B-1~B-43
19:00 Commendation
Ceremony20:00 (19:30-21:00)
(9:10~10:50)
Host Laboratory seminars
Date: 27th February
Place and Style
These seminars are held by each host laboratory to know invited guests and their works
and to form friendships with each other before the symposium. Some of these seminars will
include the presentations by the invited guests and the discussions about the works of the
invited guests and/or the members in the host laboratory. But styles of these seminars
depend on each host laboratory, so please contact each host laboratory for more
information.
Host laboratory and invitation list
Chan-Yen Ou : 上村研 (Uemura lab.)
Elisa Pieri : 加藤研 (Kato lab.)
Frank Shewmaker : 山本研 (Yamamoto lab.)
Giada Mattiuzzo : 小柳研 (Koyanagi lab.)
Humberto Sanchez : 竹安研 (Takeyasu lab.)
Kian-Huat Lim : 垣塚研 (Kakizuka lab.)
Laura Oliva : 淀井研 (Yosoi lab.)
Marie-Theres Schmid : 影山研 (Kageyama lab.)
Michael W. Tusche : 米原研 (Yonehara lab.)
Nadine C. Salisch : 三浦研 (Miura lab.)
Oscar Gee Wan Wong : 根岸研 (Negishi lab.)
Qian Yang : 西田研 (Nishida lab.)
Steffen Vanneste : 佐藤研 (Sato lab.)
Vivien Exner : 河内研 (Kohchi lab.)
Symposium
Date: 28th February – 1st March
Place: Kyodai Kaikan
Language: English
Oral presentation
Time: presentation 18 min, discussion 5 min
Room: 101
Notice for presenters: Please come to the room before your session.
Poster presentation
Time: 17:30 - 19:00 (28th February - 1st March)
Room: 201
Notice for presenters: Please set up your poster by noon on 28th March.
Commendation ceremony of excellent oral and poster presentations
Time: 19:30 – 21:00 (1st March)
Room: 101
Judges 1: Affiliation
2: Research Fields (Themes / Interests)
3: Comments
Dr. Akinori Noma / Professor / 野間 昭典 教授
1: Department of Physiology and Biophysics, Graduate School of Medicine, Kyoto University
2: Cardiac Physiology
3: The individual cellular function is composed of a large variety of molecular interactions. To
understand the complex mechanisms underlying these cellular functions, we need to integrate
molecular function into a cell model in a quantitative manner. The approach of Systems Biology
is one of the promising methods for integration. Indeed in the field of cardiac physiology, the
homeostatic mechanisms underlying the cardiac myocyte contracting activity are now explained
by integrating ion channels, ion transporters, cardiac membrane excitation, contraction and
energy metabolism into a comprehensive cell model.
Mr. Douglas Sipp / Manager
1: RIKEN Center for Developmental Biology
2: Science communications
3: I am very much looking forward to learning from this year’s group of international student
delegates. Last year’s event was excellent and I anticipate even more energy and enthusiasm
in the presentations this year. Relax, enjoy, and show your excitement!
Dr. Fumio Matsuzaki / Group Director / 松崎 文雄 グループディレクター
1: Laboratory of Cell Asymmetry, RIKEN Center for Developmental Biology
2: Neural development, Neural Stem Cell, Cell Polarity
3: You may not need to speak English to do original work. Once you have done it, then you will
definitely need to speak English, and will get better chances to do more original work.
Dr. Ikue Mori / Professor / 森 郁恵 教授
1: Laboratory of Molecular Neurobiology, Institute for Advanced Research, Division of Biological
Science, Graduate School of Science, CREST, JST, Nagoya University
2: Molecular Genetics, Behavioral Genetics, Neuroscience
3: Research fields in Bioscience are diverse and sophisticated nowadays. Scientists in
Bioscience for the next decades must be equipped with expertise in multiple disciplines to meet
the various scientific needs in the society. Challenging the function of brain for example requires
the broad knowledge ranging from experimental psychology to behavioral genetics and also the
appreciation to experimental skills such as electrophysiology and computational biology. I would
like graduate students to grasp the current scientific world, let alone to be eager to learn, to be
thoughtful and to be creative.
Dr. Ikuko Nishimura / Professor / 西村 いくこ 教授
1: Department of Botany, Graduate School of Science, Kyoto University
2: Plant Molecular Biology
3: Where there is life, there is science.
Dr. Kazuhiko Igarashi / Professor / 五十嵐 和彦 教授
1: Department of Biochemistry, Tohoku University School of Medicine
2: Regulation of gene expression and chromatin
3: Doing science can be a life-long adventure with so many funs and excitements. You can
explore what you like with taxpayers’ money. The corollary is that you have to work productively
to make discoveries and to communicate well. Please enjoy your own quiet progress.
Dr. Makoto Noda / Professor / 野田 亮 教授
1: Department of Molecular Oncology, Graduate School of Medicine, Kyoto University
2: Molecular Oncology
3: Our group is interested in the molecular mechanisms of cancer progression and now
focusing on a molecule (named RECK) that regulates extra-cellular matrix remodeling. The
techniques we use include cDNA expression cloning in mammalian cells, cell migration assay
using time-lapse microscopy, retroviral and adenoviral gene transfer, and conditional gene
targeting in mice. In this international seminar, I look forward to learning your efforts, findings,
and excitement.
Dr. Michiyuki Matsuda / Professor / 松田 道行 教授
1: Department of Pathology and Biology and Diseases, Graduate School of Medicine, Kyoto
University
2: Signal transduction, Oncogene, FRET imaging
3: Many feats in science have been achieved by serendipity. For me, daily research is to
maximize the chances to hit upon such unexpected findings. If my research progresses as I
write in grant applications, it must be horribly boring. I am looking forward to this meeting
because young scientists are bold enough to present “something terribly weird”, which makes
me exciting. Hope you also enjoy searching for the hidden clue to the secret of life.
Dr. Shunichi Takeda / Professor / 武田 俊一 教授
1: Department of Radiation Genetics, Graduate School of Medicine, Kyoto University
2: Molecular Biology、Cellular Biology
3: Compare to my days as a graduate student, nearly twenty years ago, I am amazed by the
high standards and the progress of research in current biological sciences. I hope you will all
take advantage of the wide range of fields of study that are available to broaden your horizon
sufficiently for a successful future career.
Dr. Tokuko Haraguchi / Chief Scientist / 原口 徳子 主任研究員
1: Cell Biology Project, Biological ICT Group, Kansai Advanced Research Center,
National Institute for Information and Communications Technology
2: Cell Biology, Molecular Imaging
3: Do NOT fear a failure. Barriers to your research goal exist inside your mind. Break the
barriers, and go ahead to your own research goal.
Dr. Yasushi Kawaguchi / Assistant Professor / 川口 寧 助教授
1: Division of Viral Infection, Department of Infetious Disease Control, Research Center for
Infetious Diseases, The Institute of Medical Science, The University of Tokyo
2: Virology
3: It my great pleasure to join 5th ISS in Kyoto University as a judge for presentations of young
scientists. Hopefully we will have fruitful discussions in the seminar and these will provide
insights into future researches for you guys !!
Dr. Yoshinori Watanabe / Professor / 渡辺 嘉典 教授
1: Laboratory of Chromosome Dynamics, Institute of Molecular and Cellular Biosciences, The
University of Tokyo
2: Chromosome segregation
3: It will be great to exchange scientific and non-scientific information between young
researchers face-to-face across countries. That will enormously encourage young people to
engage in scientific study and to play an important role in this community in future. I am looking
forward to hearing your enthusiastic presentation and discussion in Kyoto soon.
Oral Presentation 28th February
8:30 – Registration
9:00 – 9:10
Opening Remarks by Dr. Shin Yonehara (The head of the 21st Century COE Program)
Opening Remarks by Yasufumi Hashimoto (The chair of the 5th ISS Executive Committee)
Session A: Cell Polarity and Adhesion (9:10-10:50) Chair: Daichi Sato
9:10-9:12 Introduction
9:12-9:35 (Oral-1)
Tetsuhiro Kakimoto (Graduate School of Biostudies, Kyoto University)
Regulation of Neuronal Morphology by Toca-1 that Induces Plasma Membrane Invagination
9:36-9:59 (Oral-2)
Marie-Theres Schmid (Institute for Stem Cell Research, GSF, Munich)
Loss of adherens junctions promotes proliferation but still allows the sequential generation of
cortical neurons
10:00-10:23 (Oral-3)
Tetsuhisa Otani (Graduate School of Biostudies, Kyoto University) Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells 10:24-10:47 (Oral-4)
Hiroaki Yamanaka (Graduate School of Biostudies, Kyoto University)
Wnt11 stimulation induces polarized accumulation of Dishevelled at apical adherens junctions
through Frizzled 7
10:50-11:05 Break
Session B: Mechanisms of Morphogenesis (11:05-12:20) Chair: Shota Chiyoda
11:05-11:07 Introduction
11:07-11:30 (Oral-5)
Daisuke Satoh (Graduate School of Biostudies, Kyoto University)
Control of Proximal-Distal Distribution of Branching Points in Dendritic Trees
11:31-11:54 (Oral-6)
Steffen Vanneste (Department of Plant Systems Biology, VIB, Ghent University, Belgium)
Cell cycle progression is not sufficient for SOLITARY ROOT/IAA14 dependent lateral root
initiation
11:55-12:18 (Oral-7)
Vivien Exner (Institute of Plant Sciences, ETH Zurich, Switzerland)
Chromatin assembly factor CAF-1 is required for cellular differentiation during plant
development 12:20-13:50 Lunchtime Session C: Cooperative function of Complex (13:50-15:30) Chair: Shunsuke Kuroki
13:50-13:52 Introduction
13:52-14:15 (Oral-8)
Mina Nakama (Institute for Virus Research, Kyoto University)
Non-coding RNA associates with Histone H3 in the heterochromatin-mediated silencing
14:16-14:39 (Oral-9)
Tomoichiro Miyoshi (Graduate School of Biostudies, Kyoto University)
The Pot1 complex maintains telomere integrity in fission yeast
14:40-15:03 (Oral-10)
Qian Yang (Life Sciences Institute, University of Michigan, Ann Arbor, USA)
Identification of Sin1 as an essential TORC2 component required for complex formation and
kinase activity
15:04-15:27 (Oral-11)
Koji Onomoto (Institute for Virus Research, Kyoto University)
Signal transduction by oligomerization of RIG-I CARD 15:30-16:00 Coffee Break Session D: Approaches from Biomolecular Structure (16:00-17:15) Chair: Yasuhiko Shinoda
16:00-16:02 Introduction
16:02-16:25 (Oral-12)
Kazuki Izumi (Institute for Virus Research, Kyoto University)
Characterization of HIV-1 resistant to a peptide fusion inhibitor, N36
16:26-16:49 (Oral-13)
Frank Shewmaker (NIH, U. S. A.)
The [PSI+] Prion is an Amyloid Consisting of In-Register Parallel Beta-Sheets
16:50-17:13 (Oral-14)
Humberto Sanchez (Department of Microbial Biotechnology, CNB Autonoma, University of Madrid)
RecN: a prokaryotic SMC-like protein involve in DNA repair
17:15-17:30 Break
17:30-19:00 Poster Presentation (A-1~43)
Oral Presentation 1st March
Session E: Functional Regulation by Quantity of Protein
(9:00-10:15) Chair: Itaru Imayoshi
9:00-9:02 Introduction
9:02-9:25 (Oral-15)
Yasutaka Niwa (Institute for Virus Research, Kyoto University)
New molecular mechanism regulating Hes7 oscillation in the somite segmentation clock
9:26-9:49 (Oral-16)
Chan-Yen Ou (Graduate Institute of Life Science, National Defense Medical Center and
Academia Sinica, Taiwan)
Suppression of Hedgehog signaling by Cul3 ligases in Drosophila retinal development
9:50-10:13 (Oral-17)
Seiko Ishihara (Graduate School of Biostudies, Kyoto University)
Functional analysis of the psbP gene family in tobacco using differential RNA interference
10:15-10:30 Break
Session F: Scientific Technology and Society (10:30-12:10) Chair: Yasushi Tani
10:30-10:32 Introduction
10:32-10:55 (Oral-18)
Ryuma Shineha (Graduate School of Biostudies, Kyoto University)
The history and creation process of laws regulating the use of GMOs in Japan
10:56-11:19 (Oral-19)
Nadine C. Salisch (New England Primate Research Center, Harvard Medical School,
Southborough)
Modulation of PD-1 expression on naive and memory T cells in SIV-infected macaques
11:20-11:43 (Oral-20)
Giada Mattiuzzo (Wohl Virion Center, Division of Infection and Immunity, University College
London, London)
PERV-A receptors: determinants of host range
11:44-12:07 (Oral-21)
Elisa Pieri (ESRC Centre for Economic and Social Aspects of Genomics IAS Building, County
South Lancaster University)
Issues in Public Engagement and Accountability: a UK qualitative study of personalized
medicine
12:10-13:50 Lunchtime Session G: Intracellular Dynamics and Cell Responses (13:50-15:05) Chair: Yasufumi Hashimoto
13:50-13:52 Introduction
13:52-14:15 (Oral-22)
Takeshi Yoshida (Institute for Virus Research, Kyoto University)
CD63 and its mutants disrupt CXCR4 trafficking to the plasma membrane and inhibit T-cell
tropic HIV-1 entry
14:16-14:39 (Oral-23)
Toshihiko Kato (Graduate School of Biostudies, Kyoto University)
Metabolism of the Free Oligosaccharides in the cytosol of C. elegans
14:40-15:03 (Oral-24)
Laura Oliva (DiBiT, San Raffaele Scientific Institute, and Università Vita-Salute San Raffaele,
Milano, Italy)
Does plasma cell differentiation instill memory of gene expression programs to cope with ER
stress?
15:05-15:35 Coffee Break Session H: Cell Fate Determination (15:35-17:15) Chair: Masafumi Yoroisaka
15:35-15:37 Introduction
15:37-16:00 (Oral-25)
Michael W. Tusche (Department of Immunology, Faculty of Medicine, University of Toronto)
Bcl10 and MALT1 are essential for BAFF-induced cellular outcomes
16:01-16:24 (Oral-26)
Masatoshi Ohgushi (Graduate School of Biostudies, Kyoto University)
TGF-β regulates cellular life-or-death by utilizing Slug and Bim
16:25-16:48 (Oral-27)
Oscar Gee Wan Wong (Prostate Cancer Research Centre, University College London, London
W1W 7EJ, UK)
A mutation in the Plexin-B1 gene frequently found in prostate cancer metastasis affects
Plexin-B1’s function on Rac
16:49-17:12 (Oral-28)
Kian-Huat Lim (Department of Pharmacology and Cancer Biology Duke University Medical Center)
The Roles of RalGTPases in Oncogenesis of Human Cells
17:15-17:30 Break
17:30-19:00 Poster Presentation (B-1~43)
Poster Presentation (17:30-19:00 28th February)
Group 1: Cell Polarity and Adhesion
A-1 (Oral-4)
Hiroaki Yamanaka, Eisuke Nishida (Biostudies)
Wnt11 stimulation induces polarized accumulation of Dishevelled at apical adherens junctions
through Frizzled 7
A-2 (Oral-5)
Daisuke Satoh, Daichi Sato, Taiichi Tsuyama, Melissa M. Rolls, Chris Q. Doe, Hiroyuki
Ohkura, Motoki Saito, Fuyuki Ishikawa, Tadashi Uemura (Biostudies)
Control of Proximal-Distal Distribution of Branching Points in Dendritic Trees
A-3
Kiyo Hiramoto, Hironori Katoh, Manabu Negishi (Biostudies)
Dock4 is regulated by RhoG and promotes Rac-dependent cell migration
A-4
Daichi Sato, Daisuke Satoh, Taiichi Tsuyama, Kaoru Sugimura, Tadashi Uemura (Biostudies)
Genetic dissection of geometry of dendritic trees
A-5 (Oral-3)
Tetsuhisa Otani, Tetsuo Ichii, Shinya Aono, Masatoshi Takeichi (Biostudies)
Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells.
A-6 (Oral-2)
Marie-There Schmid, Franziska Weinandy Weinandy, Magdalena Gotz
(Institute for Stem Cell Research, GSF, Munich)
Loss of adherens junctions promotes proliferation but still allows the sequential generation of
cortical neurons
Group 2: Differentiation and Morphogenesis
A-7
Kiminori Takahata, Fumihiko Sato (Biostudies)
Induction of early flowering in Arabidopsis thaliana by ectopic of C-ESE1, a unique gene
involved in somatic embryogenesis of carrot cells
A-8
Hideo Kataoka, Keiko Mukougawa, Katsuyuki T. Yamato, Takayuki Kohchi (Biostudies)
Functional analysis of the ancestral phytochrome in the liverwort Marchantia polymorpha
A-9
Takahiro Kimura, Michitaka Notaguchi, Yasuhumi Daimon, Mitsutomo Abe, Takashi Araki
(Biostudies)
The study of the importance of FT mRNA sequence for long-distance movement in Arabidopsis
A-10
Shuhei Toriumi, Yasufumi Daimon, Takashi Araki (Biostudies)
Study of the FT function as a part of the transcription complex
A-11
Masaki Kobayashi, Yasuhumi Daimon, Mitsutomo Abe, Takashi Araki (Biostudies)
Toward Identification of Functionally Important Domains of FT Protein
A-12 (Oral-1)
Tetsuhiro Kakimoto, Hironori Katoh, Manabu Negishi (Biostudies)
Regulation of Neuronal Morphology by Toca-1 that Induces Plasma Membrane Invagination
A-13
Kaoru Sugimura, Tadashi Uemura, Atsushi Mochizuki (Biostudies)
Self-organized Mechanism for Development of Space-filling Dendrites
A-14
Yukako Hattori, Kaoru Sugimura, Tadashi Uemura (Biostudies)
Selective Expression of Knot/Collier Endowed a Class-specific Dendritic Morphogenesis
A-15
Asako Tsubouchi, Taiichi Tsuyama, Toshiro Aigaki, Tadashi Uemura (Biostudies)
Mitochondrial Protein Preli Regulates Maintenance Dendritic Branches in Drosophila Neurons
A-16 (Oral-7)
Vivien A Exner, Wilhelm Gruissem, Lars Hennig
(Institute of Plant Sciences, ETH Zurich, Switzerland)
Chromatin assembly factor CAF-1 is required for cellular differentiation during plant
development
A-17
Nengah Suwastika, Masatsugu Denawa, Ryosuke L. Ohniwa, Takashi Shiina, Kunio
Takeyasu (Biostudies)
Plant Obg and Era Homologues Targeted to Different Organelles of Arabidopsis Cell
A-18
Masahiro Kishine, Yoko Ishizaki, Atsushi Takabayashi, Takashi Shiina, Tsuyoshi Endo,
Fumihiko Sato (Biostudies)
Post-transcriptional regulation of chloroplast gene expression by RNase E in Arabidopsis
A-19
Shota Chiyoda, Philip J. Linley, Katsuyuki T. Yamato, Hideya Fukuzawa, Akiho Yokota,
Takayuki Kohchi (Biostudies)
Simple and efficient plastid transformation system of the liverwort Marchantia polymorpha L.
A-20 (Oral-6)
Steffen Vanneste, Dirk Inzé, Tom Beeckman
(Department of Plant Systems Biology, VIB, Ghent University, Belgium)
Cell cycle progression is not sufficient for SOLITARY ROOT/IAA14 dependent lateral root
initiation
A-21
Satoko Nishimoto, Eisuke Nishida (Biostudies)
FGF13 regulates neural differentiation in Xenopus embryonic development
A-22
Hiroshi Kokubu, Toshiyuki Ohtsuka, Ryoichiro Kageyama (IVR)
Mash1 is required for endocrine cell development in the glandular stomach
Group 3: Approaches from Biomolecular Structure
A-23
Hirohide Takahashi, Shinji Kawano, Yasuhiro Hirano, Ken Tsutsui, Kimiko Tsutsui, Shige
H. Yoshimura, Kunio Takeyasu (Biostudies)
Efficient modifications of AFM cantilever and applications to the recognition imaging
A-24
Shotaro Otsuka, Hirohide Takahashi, Kunio Takeyasu, Shige, H Yoshimura (Biostudies)
Single-molecule analyses of the interactions between importin β and nuclear pore complex
A-25
Jun Wada, Takane Katayama, Ryuichiro Suzuki, Shinya Fushinobu, Motomitsu Kitaoka,
Hayuki Sugimoto, Akiyoshi Tanaka, Hidehiko Kumagai, Hisashi Ashida, Kenji Yamamoto
(Biostudies)
Studies on the lacto-N-biose/galacto-N-biose transporter of bifidobacteria
A-26
Takuma Sugi, Takuji Oyama, Takanori Muto, Shigetada Nakanishi, Kosuke Morikawa,
Hisato Jingami (Biostudies)
Regulation of Metabotropic Glutamate Receptor Trafficking by Autoinhibition and Its Release of
a Scaffold Protein Tamalin
A-27 (Oral-12)
Kazuki Izumi, Eiichi Kodama, Shota Nakamura, Hiroaki Nakano, Shinya Oishi, Nobutaka
Fujii, Masao Matsuoka (IVR)
Characterization of HIV-1 resistant to a peptide fusion inhibitor, N36
A-28 (Oral-13)
Frank Shewmaker, Robert Tycko, Reed Wickner
(NIH, U. S. A.)
The [PSI+] Prion is an Amyloid Consisting of In-Register Parallel Beta-Sheets
A-29
Masahiro Kumeta, Yu-ya Hirai, Yasuhiro Hirano, Shige H. Yoshimura, Kunio Takeyasu
(Biostudies)
Nucleolar dynamics revealed by monoclonal antibodies against nuclear proteins
A-30
Yasuhiro Hirano, Hirohide Takahashi, Tsuneyoshi Horigome, Shige. H. Yoshimura, Kunio
Takayasu (Biostudies)
Biochemical analyses combined with single molecule mechanics reveal the Binding mechanism
Group 4: Transcription and Chromatin Dynamics
A-31
Rei Yoshimoto, Naoyuki Kataoka, Mutsuhito Ohno (IVR)
Isolation of the post-splicing intron complex
A-32
Ichiro Taniguchi, Mutsuhito Ohno (IVR)
ATP-dependent recruitment of export factor REF to mRNA by RNA helicase-like protein UAP56
A-33 (Oral-14)
Humberto Sanchez, Juan C Alonso, Kunio Takeyasu
(Department of Microbial Biotechnology, CNB Autonoma, University of Madrid)
RecN: a prokaryotic SMC-like protein involve in DNA repair
A-34
Naoko Somete, Akira Nabetani, Hiroshi Kimura, Fuyuki Ishikawa (Biostudies)
Histone H1 dynamics in stress-applied living cells
A-35
Megumi Fujita, Naoyuki Kataoka, Mutsuhito Ohno (IVR)
Production of microRNAs from introns of protein coding genes
A-36 (Oral-8)
Mina Nakama, Yota Murakami (IVR)
Non-coding RNA associates with Histone H3 in the heterochromatin-mediated silencing
A-37
Tomohiro Asano, Junko Kanoh, Fuyuki Ishikawa (Biostudies)
Chromatin structure modification during the sexual reproduction in fission yeast
A-38
Joongbaek Kim, Ryosuke L Ohniwa, Chieko Wada, Kunio Takeyasu (Biostudies)
Bacterial chromosome architecture and dynamics
Group 5: Cooperative Function of Complex
A-39 (Oral-9)
Tomoichiro Miyoshi, Miyoshi, Motoki Saito, Fuyuki Ishikawa (Biostudies)
The Pot1 complex maintains telomere integrity in fission yeast
A-40
Keiji Okamoto, Tomohiko Iwano, Makoto Tachibana, Yoichi Shinkai (IVR)
Function of telomeric proteins in mouse TRF1 conditional knockout ES cells
A-41 (Oral-10)
Qian Yang, Ken Inoki, Tsuneo Ikenoue, Kun-Liang Guan
(Life Sciences Institute, University of Michigan, Ann Arbor, USA)
Identification of Sin1 as an essential TORC2 component required for complex formation and
kinase activity
A-42
Ryo Narita, Reiko Hirai, Mitsutoshi Yoneyama, Takashi Fujita (IVR)
Analysis of the enzymatic activities of the RNA helicase RIG-I
A-43 (Oral-11)
Koji Onomoto, Mitsutoshi Yoneyama, Takashi Fujita (IVR)
Signal transduction by oligomerization of RIG-I CARD
Poster Presentation (17:30-19:00 1st May)
Group 6: Quantity control and Oscillation of Proteins
B-1 (Oral-15)
Yasutaka Niwa, Yoshito Masamizu, Tianxiao Liu, Rika Nakayama, Chu-Xia Deng,
Ryoichiro Kageyama (IVR)
New molecular mechanism regulating Hes7 oscillation in the somite segmentation clock
B-2
Shigeki Yoshiura, Toshiyuki Ohtsuka, Yoshiko Takenaka, Hiroki Nagahara, Kenichi
Yoshikawa, Ryoichiro Kageyama (IVR)
Oscillations of Stat, Smad and Hes in cultured cells
B-3
Kei Nakayama, Takayuki Satoh, Ryoichiro Kageyama, Eisuke Nishida (Biostudies)
FGF induces oscillations of Hes1 expression and Ras/ERK activation
B-4 (Oral-16)
Chan-Yen Ou, Chien-Hsiang Wang, Jin Jiang, Cheng-Ting Chien
(Graduate Institute of Life Science, National Defense Medical Center and Academia Sinica,
Taiwan)
Suppression of Hedgehog signaling by Cul3 ligases in Drosophila retinal development
B-5 (Oral-17)
Seiko Ishihara, Yumiko Yamamoto, Kentaro Ifuku, Fumihiko Sato (Biostudies)
Functional analysis of the psbP gene family in tobacco using differential RNA interference
Group 7: Metabolisms and Signals of Lipids and Carbohydrate
B-6 (Oral-23)
Toshihiko Kato, Hisashi Ashida, Kenji Yamamoto (Biostudies)
Metabolism of the Free Oligosaccharides in the cytosol of C. elegans
B-7
Nobuhito Kittaka, Takumi Sumimoto, Takahiro Tsuzuki, Hisanori Tamaki (Biostudies)
Studies on type II platelet-activating factor acetylhydrolase in fission yeast.
B-8
Akito Makino, Hiromu Takematsu, Yasunori Kozutsumi (Biostudies)
Pil1 is required for the proper function of Mss4 in yeast
B-9
Maki Riichi, Hayato Ozawa, Akihito Kawahara, Shin Kurihara, Masaya Fujita, Hisashi
Ashida, Kenji Yamamoto (Biostudies)
Novel endoglycosidase of Clostridium perfringens with wide substrate specificity
B-10
Midori Umekawa, Kiyotaka Fujita, Toshihiko Katoh, Hisashi Ashida, Kenji Yamamoto
(Biostudies)
Improvement of endo-β-N-acetylglucosaminidase from Mucor hiemallis (Endo-M)
B-11
Yumi Ando, Hiromu Takematsu, Harumi Yamamoto, Yasushi Okuno, Yasunori Kozutsumi
(Biostudies)
DNA microarray-based analysis to identify enzyme genes regulating glycan expression
Group 8: Immune system
B-12
Koji Nagaoka, Kazuhiko Takahara, Kayo Inaba (Biostudies)
Expression analysis of mouse C-type lectin SIGNR3
B-13
Kazuhide Onoguchi, Mitsutoshi Yoneyama, Azumi Takemura, Shizuo Akira, Tadatsugu
Taniguchi, Takashi Fujita (IVR)
Viral Infections Activate Type I and Type III Interferon Genes Through a Common Mechanism
B-14
Kento Minamino, Kazuhiko Takahara, Sinsuke Taki, Kayo Inaba (Biostudies)
Effect of interferon regulatory factor-2 on the development and differentiation of B cells
B-15 (Oral-25)
Michael W. Tusche, Lesley A. Ward, Jennifer L. Gommerman, Tak W. Mak
(Department of Immunology, Faculty of Medicine, University of Toronto)
Bcl10 and MALT1 are essential for BAFF-induced cellular outcomes
B-16 (Oral-24)
Laura Oliva, Elisa Benasciutti, Queralt Seguin, Michal Krawczyk, Walter Reith, Roberto
Sitia, Simone Cenci
(DiBiT, San Raffaele Scientific Institute, and Universita’ Vita-Salute San Raffaele, Milano, Italy)
Does plasma cell differentiation instill memory of gene expression programs to cope with ER
stress?
B-17
Shinya Ogawa, Masanobu Satake, Koichi Ikuta (IVR)
The interaction between transcription factors STAT5 and RUNX suppresses each other’s
transcriptional activity
B-18
Masaki Moriyama, Kohei Kometani, Masakazu Hattori, Nagahiro Minato (Biostudies)
Involvement of Rap1 signaling on β-selection in T cell development
Group 9: Virus Infection
B-19 (Oral-20)
Giada Mattiuzzo, Magda Matouskova, Yasuhiro Takeuchi
(Wohl Virion Center, Division of Infection and Immunity, University College London, London)
PERV-A receptors: determinants of host range
B-20 (Oral-22)
Takeshi Yoshida, Yuji Kawano, Yoshinori Ando, Kei Sato, Yoshiharu Miura, Jun Komano,
Yuetsu Tanaka, Yoshio Koyanagi (IVR)
CD63 and its mutants disrupt CXCR4 trafficking to the plasma membrane and inhibit T-cell
tropic HIV-1 entry
B-21
Kenji Baba, Kazuya Nakamura, Hibiki Koizumi, Takayuki Shojima, Masaya Okada, Rika
Nakamura, Mieko Ishikawa, Takayuki Miyazawa (IVR)
Defective viral replication in human embryonic kidney-derived 293 cells chronically infected with
porcine endogenous retrovirus (PERV)
B-22
Kenta Matsuda, Megumi Matsuyama, Kentaro Ibuki, Yumi Yamaguchi, Tomoyuki Miura
(IVR)
Construction of R5 single tropic virus and X4 single tropic virus using dual tropic SHIV-KS661
as a backbone
B-23 (Oral-19)
Nadine C. Salisch, David Evans, R. Paul Johnson
(New England Primate Research Center, Harvard Medical School, Southborough)
Modulation of PD-1 expression on naïve and memory T cell in SIV-infected macaques
B-24
Misa Ishimatsu, Hajime Suzuki, Hisashi Akiyama, Masanori Hayami, Tomoyuki Miura, Eiji
Ido (IVR)
Evaluation of a novel SHIV having an HIV-1-derived pr gene / macaque model for protease
inhibitors
Group 10: Science Communication
B-25 (Oral-21)
Elisa Pieri
(ESRC Centre for Economic and Social Aspects of Genomics IAS Building, County South
Lancaster University)
Issues in Public Engagement and Accountability: a UK qualitative study of personalised
medicine
B-26
Kentaro Matsuda, Kae Takahashi, Tetsuya Shirai, Masahiro Kawakami, Kazuto Kato
(Biostudies)
What is “Science Cafe”? and the Practice of “OSHABERI GENOME” in Genome Square 2006
B-27 (Oral-18)
Ryuma Shineha, Kazuto Kato (Biostudies)
The history and creation process of laws regulating the use of GMOs in Japan
Group 11: Environment and Cellular Responses
B-28
Takashi Yamano, Tomoki Tsujikawa, Hideya Fukuzawa (Biostudies)
A role of LCIB protein responsible for acclimation to CO2-limiting stress
B-29
Akimitsu Fujita, Norikazu Ohnishi, Tsutomu Kohinata, Takashi Yamano, Yousuke
Yamahara, Hideya Fukuzawa (Biostudies)
Structural comparison of CO2-signaling factors, CCM1s, between Volvox and Chlamydomonas
B-30
Tomoka Murai, Yukiko Nakase, Keiko Fukuda, Tomohiro Matsumoto (Biostudies)
Functional analysis of the Rheb small GTPase regulating the signaling pathway of the nutrient
response
B-31
Masaki So, Shin-ichi Oka, Juniji Yodoi, Hiroshi Masutani (IVR)
Thioredoxin binding protein-2 (TBP-2) is a negative regulator of PPAR signal
B-32
Eiji Yoshihara, Shin-ichi Oka, Juniji Yodoi, Hiroshi Masutani (Biostudies)
TBP-2 is a key regulator of insulin secretion and energy metabolism on fasting
B-33
Takumi Mikawa, Junko Kanoh, Tomoichiro Miyoshi, Fuyuki Ishikawa (Biostudies)
DNA damage sensor Rad3 is involved in the response to oxidative damage of mitochondria
B-34
Masaaki Koike, Naoki Higashimae, Masahiko Fujishiro, Junpei Fukushi, Masakatsu
Noguchi, Hiroshi Ohizumi , Seiji Hori, Akira Kakizuka (Biostudies)
Modifications of VCP/p97 by Abnormal Protein Accumulation lead to Neuronal Cell Atrophy
Group 12: Cell Cycle and Cell Death Control
B-35 (Oral-27)
Oscar Gee Wan Wong, John Masters, Magali Williamson
(Prostate Cancer Research Centre, University College London, London W1W 7EJ, UK)
A mutation in the Plexin-B1 gene frequently found in prostate cancer metastasis affects
Plexin-B1’s function on Rac
B-36 (Oral-28)
Kian-Huat Lim, Kevin O’Hayer, Stacey Adam, S. DiSean Kendall, Paul Campbell, Antonio
Baines, James Fiordalisi, Adrienne Cox, Channing Der, Christopher Counter
(Department of Pharmacology and Cancer Biology Duke University Medical Center)
The Roles of RalGTPases in Oncogenesis of Human Cells
B-37
Yohei Kobayashi, Shin Yonehara (Biostudies)
Novel cell death in tetraploids via downregulation of eEF1A1/EF-1α
B-38
Daisuke Ito, Tomohiro Matsumoto (Biostudies)
Mechanism of the spindle checkpoint activation by fission yeast Mph1
B-39
Hiroyuki Nakajima, Shigenobu Yonemura, Masayuki Murata, Nobuhiro Nakamura, Helen
Piwnica-Worms, Eisuke Nishida (Biostudies)
Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit
B-40
Takuma Abe, Atsuya Nishiyama, Motoki Saito, Fuyuki Ishikawa (Biostudies)
Comprehensive identification of proteins involved in DNA replication in Xenopus egg extracts
B-41
Michika Mochizuki, Hiroshi Masutani, Yong-won Kwon, Yoshiyuki Matsuo, Mikiko
Kobayashi-Miura, Junji Yodoi (Biostudies)
Thioredoxin controls cell cycle and cell death
B-42 (Oral-26)
Masatoshi Ohgushi, Takuya Yamamoto, Andreas Strasser, Eisuke Nishida, Shin
Yonehara (Biostudies)
TGF-β regulates cellular life-or-death by utilizing Slug and Bim.
B-43
Hirokazu Nakatsumi, Shin Yonehara (Biostudies)
Identification of domains responsible for different in vivo activities of executer caspase
*Biostudies: Graduate School of Biostudies, Kyoto University
*IVR: Institute for Virus Research, Kyoto University
Group Seminar
Date: 2nd March (9:00~)
Place
NeoII (Building G in Faculty of Medicine campus) *Please refer the access map.
Style
The aims of the Group Seminar are to discuss the works across borders, to understand the
works in different fields and to shear the scientific experience. Each group will consist of 2
invited guests and 3-5 young Japanese scientists from various research fields. Each member of
the group will present their studies using mainly the posters which are used in the poster
presentation. Other supplementary materials such as PC and pictures also can be used. Times
of presentations are as follow.
Those who present a study in both oral and poster session: ~7 minutes (talk)
Those who present a study in the poster session only: ~12 minutes (talk)
Question-and-answer can be exchanged anytime during presentation. Chairpersons of these
seminars are the members of the 5thISS executive committee.
In this seminar, we hope to talk the future of life science and to form good friendships between
fields for us and for the future of life science.
Groups and Rooms Group 1 Presenters:
Laura Oliva, Marie-Theres Schmid,
Kiyo Hiramoto, Nobuhito Kittaka,
Shota Chiyoda
Chairperson: Yasushi Tani
Room: 1F lecture room
Group 5 Presenters:
Elisa Pieri, Giada Mattiuzzo,
Megumi Fujita, Mina Nakama, Shotaro Otsuka
Chairperson: Katsuhisa Inaba
Room: 2F room D
Group 2 Presenters:
Chan-Yen Ou, Vivien Exner,
Kazuhide Onoguchi, Masaaki Koike
Chairpersons: Yasuhiko Shinoda, Yuri Ito
Room: 2F room A
Group 6 Presenters:
Oscar Gee Wan Wong, Steffen Vanneste,
Daichi Sato, Takahiro Kimura
Chairperson: Yasufumi Hashimoto
Room: 5F conversation room
Group 3 Presenters:
Kian-Huat Lim, Nadine C. Salisch,
Hirohide Takahashi, Koji Onomoto,
Masaki Kobayashi
Chairpersons: Itaru Imayoshi, Shunsuke Kuroki
Room: 2F room B
Group 7
Presenters:
Humberto Sanchez, Qian Yang,
Kento Minamino, Shuhei Toriumi
Chairpersons: Kaori Muroi, Masafumi Yoroisaka
Room: 5F conference room
Group 4 Presenters:
Frank Shewmaker, Michael Tusche,
Eiji Yoshihara, Ryuma Shineha, Ryo Narita
Chairperson: Kunio Ido
Room: 2F room C