the diabetes health profile (dhp) development journey 1986 initial development of the dhp-1 patient...
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THE DIABETES HEALTH PROFILE (DHP) DEVELOPMENT JOURNEY
1986Initial
development of the DHP-1
Patient input
25 In-depth patient interviewsLiterature
review +DHP Conceptual model
The DHP-1 and DHP-18 are standardised diabetes-specific measures of the impact of diabetes on psychological and behavioural dysfunctioning in Type 1 and Type 2 diabetes respectively. Compliant with FDA guidelines on PRO developments for label claims.
Through a combination of factor analyses, internal reliability, construct, convergent and discriminant validity the 32-item DHP-1 conceptual framework is defined for Type 1 & Type 2 Insulin requiring patients. Compliant with FDA guidelines on PRO developments for label claims. • Meadows et al 1996; Qual Life Res; 5: 242-254; Goddjin et al. 1996; Qual Life Res; 5: 433-442
1986-1996DHP-1
Conceptual framework
development
1996-2000DHP-18
Conceptual frameworkdeveloped
From the original 32-item DHP-1 the 18-item DHP-18 conceptual framework is derived for use with Type 1 and Type 2 diabetes including insulin, oral and diet. Compliant with FDA guidelines on PRO developments for label claims. • Meadows et al. Diabetic Med 2000; 17: 572-580.
10,000Type 1 & Type 2
RespondentsHave completed the
DHP-1 / DHP-18
More than
2000-2013Current
& previous users of the
DHP-1/DHP-18
Oral
Insulin
44 46 48 50 52 54 56
Disinhibeted eat-ingPsycholigical dis-tressBarriers to activity
Score 0=No dysfunctioning p<0.05
35-44 45-54 55-64 65-74 >75
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Patients reporting severe hy-
poglycaemic epis-odes
Mean age63.9 years91% Type 2 and 9% Type 1
patients completed the questionnaire.
Patients (mean) scores on the Disinhibited eating domain by BMI
BMI<25
BMI25-34
BMI>35
55%
45%
47.849.2
52.4
Psychological distress
MOST AT RISK
• Comorbidity
• Severe hypoglycaemia
• Female
• > Age
• Visit to the pyschiatrist
ANOVA p=0.05
An example of what the DHP-1/DHP-18 can tell usSource: Boini et al. Health and Quality of Life Outcomes; 2010; 8:124
Psychological distress
3173
2013New
Developments
Investigating the minimally important difference of the Diabetes Health Profile (DHP-18) and the EQ-5D and SF-6D in a UK diabetes mellitus population
Forthcoming research article
For licensing enquiries contact Isis OutcomesEmail: [email protected]: : +44 (0)1865 280857www.isis-innovation.com/outcomes/
For further information on the Diabetes Health Profile visit www.diabetesprofile.comEmail:[email protected]
Copyright DHP Research & Consultancy Ltd 2013 . All rights reserved
Diabetes Health Profile (DHP) Licensing Association with Isis Outcomes.
Develops eDHP