The ECDC public health microbiology programme 2015-16

14th National Microbiology Focal Points meeting

Marc Struelens, Chief Microbiologist on behalf of

Microbiology Coordination Section, Office of the Chief Scientist European Centre for Disease Prevention and Control14th NMFP, Stockholm, 12-13 May 2016

Microbiology Coordination Team

Marc Struelens - Chief Microbiologist, Head of Section

Amanda Ozin - Senior Expert Microbiology

Katrin Leitmeyer - Senior Expert Virology

Barbara Albiger - Expert Microbiology

Joana Revez - Scientific Officer

Signe Gilbro - Communication Officer Web and Social Media

Milka Docheva - Secretary

ECDC Strategic Multi-annual Programme 2014–20 Microbiology support

By 2020, ECDC has achieved:

• Consolidation of the capacity of the EU public healthmicrobiology system for European surveillance and epidemicpreparedness;

• Implementation of a system that assists Member States inmonitoring critical microbiology capabilities;

• Gradual integration of selected molecular typing data intoEuropean surveillance and epidemic investigations forpriority diseases;

• Further integration of EU clinical and public healthlaboratories in the surveillance and alert systems for humanand zoonotic pathogens

ECDC Microbiology support: weaknesses and recommendations from external evaluation

Weaknesses/challenges Recommendations

• Least known/appreciated area of ECDC work

• Communication on outputs and added value• Consider reorganisation of microbiology

outside of the disease programmes

• Credibility gap • More microbiology expert staff• Stronger coordination of DP microbiology

support by “micro unit”

• Mixed views on added value • Analysis and demonstration of added value

• Polarised MS views on molecular typing

• Ensure synergy with TESSy data analysis

• Fast moving diagnostic technology, WGS

• Perform technology assessment, cost-effectiveness analysis, guidance and pilot implementation projects

Source: The second independent evaluation of the ECDC in accordance with its Founding Regulation (European Parliament and Council Regulation (EC) no 851/2004. FINAL REPORT October 2014)

ECDC supported laboratory network activities, 2015 (N=12 network/projects*)

Source: ECDC Director Annual Report 2015

• *laboratory networks managed by ECDC Disease Programmes and two advisory committees (MSTF, EUCAST)

Type of work No. of outputs

External quality assessment 7

Technical guidance 8

Laboratory training courses 9

Technical capacity mapping 7

Cross-border testing services 6

Outbreak investigation support 3

First EULabCap report

Source: http://ecdc.europa.eu/en/publications/Publications/EU-laboratory-capability-monitoring-system-2013.pdf

Critical review of the draft report at the NMFP13/AF42 joint meeting in May 2015.

Integration of advice on: - Main conclusions- Publication format to

enable benchmarking.

Published February 2016.

Communication and consultations

Newsletter

• Project updates

• Publications, upcoming events

Extranet

• Documents for written consultation/for information

Webportal

• New microbiology page with repository of EQA

• New: capacity mapping reports/ resources

Homepage

Homepage

Proposed web repository of resources on EU laboratory capabilities

ECDC Joint Strategic Meeting September 2015 –conclusions on molecular typing

• ECDC to consolidate ongoing molecular typing forsurveillance and prioritise those pathogens/diseaseswhere it is possible to demonstrate EU public healthbenefits.

• Molecular typing for EU surveillance should undergo astepwise transition to WGS, based on continuous updateon cost, performance and assessment of public healthvalue.

• Take into account both ECDC resources and mapping ofnational capacities. ECDC should continue supportingtraditional typing methods.

Roadmap - V1.2, 2013 for integration of molecular and genomic typing into European level surveillance and epidemic preparedness

2013

Concept paper: Surveillance of communicable diseases in Europe – a concept to integrate molecular typing data into EU-level surveillance. Stockholm ECDC; 2013.

2007

2016WGS Strategy and Roadmap - V2.1, 2016-19

• Co-drafted and peer-reviewed by ECDCDiseases programmes

• Prioritised in consultation with MSTF,November 2015

• Approved internally January 2016

• Submitted for written comments to theAdvisory Forum AF 44 – February 2016

• 6 comments (Belgium, Norway, Spain,Sweden, European Commission,WHO/Europe)

• Expected publication: June, 2016

ECDC roadmap for integration of molecular and genomic typing into European level surveillance and epidemic preparedness- version 2.1, 2016-19

Communication and consultations

Meetings and expert consultations

• 22-24 September 2015 - Joint Strategic Meeting

• 19 November 2015 - WGS strategy at EU level

• 20 November 2015 - MSTF Typing Roadmap prioritisation

Surveys

• June- September 2015: National capacity/plans for WGS

• October 2015: EULabCap 2014 data call and validation

• February 2016, May 2016: ZIKV diagnostic capability

European Commission- ECDC collaboration on reference laboratories, 2015-16

• EMERGE Joint Action

Collaboration on Ebola technical guidance with QUANDHIP, ENIVD,and the European Mobile Laboratories

ECDC Observer and Advisor to the EMERGE network

Coordination and communication with ENIVD/ EVD-LabNet

• ECDC contribution to CHAFEA study on ‘Cost-benefit analysisof reference laboratories for human pathogens’

Expert workshops

Study data collection (EU lab networks as case studies)

Draft report review

Scientific advice on microbiology RTD projects, 2015-16

ECDC expert contributions/advice to:

• PathNGenTrace• PREMEDICS• PREPARE• COMPARE• GMI

International conferences

• IMMEM X, March 2016

• 26th ECCMID, April 2016

• EBSA Conference, April 2016

• RAMI-NGS Conference, June 2016

ECDC Observerships

ESCV-ESCMID Members

Thank you for listening,

ECDC.Microbiology@ecdc.europa.eu