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    The Infectious ProcessThe Infectious Process

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    The Infectious Disease ProcessThe Infectious Disease Process

    Microorganisms includeMicroorganisms include

    the followingthe following

    classifications: bacteria,classifications: bacteria,viruses, fungi, algae,viruses, fungi, algae,

    yeasts, and protozoa.yeasts, and protozoa.

    These organisms areThese organisms are

    too small to be seen bytoo small to be seen bythe unaided human eye.the unaided human eye.

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    They are found in theThey are found in the

    soil, in the water, andsoil, in the water, and

    on plants and animals.on plants and animals.In fact, billions areIn fact, billions are

    found in humans on thefound in humans on the

    skin and in both theskin and in both the

    nasal and intestinalnasal and intestinaltracts.tracts.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Although mostAlthough most

    microorganisms live inmicroorganisms live in

    harmony with the humanharmony with the human

    body, somebody, somecalledcalledpathogenspathogenscan infect thecan infect the

    body and cause disease.body and cause disease.

    Infectious diseases rangeInfectious diseases range

    from mild illnesses, such asfrom mild illnesses, such asa cold, to fatal illnesses,a cold, to fatal illnesses,

    such as AIDS.such as AIDS.

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    The Infectious Disease ProcessThe Infectious Disease Process

    We occasionally come intoWe occasionally come into

    contact with people orcontact with people or

    animals that are infectedanimals that are infected

    and thus expose ourselvesand thus expose ourselvesto the pathogens of theirto the pathogens of their

    diseases. In fact, ourdiseases. In fact, our

    environment is such thatenvironment is such that

    everyday we live with someeveryday we live with somerisk of exposure torisk of exposure to

    diseases.diseases.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Some individuals, because of theSome individuals, because of thework they do, are at risk forwork they do, are at risk foroccupationally acquired infection. Foroccupationally acquired infection. Forthis reason, special policies andthis reason, special policies and

    procedures have been developedprocedures have been developedThis program will cover:This program will cover:

    the infectious disease processthe infectious disease process

    potential exposure risks to employeespotential exposure risks to employees work practices that will minimize yourwork practices that will minimize your

    risk of exposure to pathogenicrisk of exposure to pathogenicmicroorganismsmicroorganisms

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    The Infectious Disease ProcessThe Infectious Disease Process

    The infectious disease process is definedThe infectious disease process is defined

    as the interaction between the pathogenicas the interaction between the pathogenic

    microorganism, the environment, and themicroorganism, the environment, and thehost. The process may be thought of as ahost. The process may be thought of as a

    circular chain with six links.circular chain with six links.

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    The Infectious Disease ProcessThe Infectious Disease Process

    The chainThe chain

    begins with thebegins with the

    existence of aexistence of a

    specificspecific

    pathogenicpathogenic

    microorganism.microorganism.

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    The Infectious Disease ProcessThe Infectious Disease Process

    The second linkThe second link

    is the reservoir,is the reservoir,an environmentan environment

    where thewhere the

    pathogen canpathogen can

    survive.survive.

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    The Infectious Disease ProcessThe Infectious Disease Process

    The third link is theThe third link is the

    means of escapemeans of escape

    from the reservoirfrom the reservoir

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    The Infectious Disease ProcessThe Infectious Disease Process

    The fourth link is theThe fourth link is the

    mode of transmissionmode of transmission

    from the reservoir tofrom the reservoir to

    the host.the host.

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    The Infectious Disease ProcessThe Infectious Disease Process

    The fifth link is theThe fifth link is the

    means of entry intomeans of entry into

    the host.the host.

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    The Infectious Disease ProcessThe Infectious Disease Process

    And the last link is the host's susceptibilityAnd the last link is the host's susceptibility

    to the pathogenic microorganism.to the pathogenic microorganism.

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    The Infectious Disease ProcessThe Infectious Disease Process

    For an infectiousFor an infectious

    disease to occur,disease to occur,

    each link in theeach link in the

    chain must bechain must be

    connected.connected.

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    The Infectious Disease ProcessThe Infectious Disease Process

    If even one link of theIf even one link of the

    chain is missing, itchain is missing, it

    interrupts the process,interrupts the process,

    and no infection willand no infection will

    occur.occur.

    Here the chain isHere the chain is

    broken at the point ofbroken at the point ofhost susceptibility.host susceptibility.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Here the mode ofHere the mode of

    transmission breakstransmission breaks

    the chain ofthe chain of

    infection.infection.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Hepatitis B VirusHepatitis B Virus

    The microorganism known asThe microorganism known asHepatitis B Virus (or HBV) causesHepatitis B Virus (or HBV) causesan inflammation of the liver. Thisan inflammation of the liver. This

    can result in illnesses such ascan result in illnesses such aschronic hepatitis, cirrhosis of thechronic hepatitis, cirrhosis of theliver, and liver cancer. Because theliver, and liver cancer. Because thevirus is present in the blood or bodyvirus is present in the blood or bodyfluids of a person with the Hepatiis Bfluids of a person with the Hepatiis BVirus, it is termed a blood borneVirus, it is termed a blood bornepathogen. Hepatitis B Virus is apathogen. Hepatitis B Virus is aserious health concern for anyserious health concern for anyemployee whose workemployee whose workresponsibilities bring them in contactresponsibilities bring them in contactwith blood or body fluids.with blood or body fluids.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Human Immunodeficiency VirusHuman Immunodeficiency Virus

    The Human ImmunodeficiencyThe Human ImmunodeficiencyVirus (HIV) is another blood borneVirus (HIV) is another blood bornepathogen. This lifepathogen. This life--threateningthreatening

    virus compromises the body'svirus compromises the body'simmune system. Early symptomsimmune system. Early symptomsmay be similar to those of the flu.may be similar to those of the flu.During later stages of the disease,During later stages of the disease,the body is incapable of wardingthe body is incapable of warding

    off other infections whichoff other infections whichfrequently prove fatal.frequently prove fatal.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Penetration into the BloodstreamPenetration into the Bloodstream

    Blood borne pathogens are transmitted when anBlood borne pathogens are transmitted when anindividual comes in contact with an infectedindividual comes in contact with an infected

    person's blood or body fluids. However, contactperson's blood or body fluids. However, contactalone does not mean infection will result.alone does not mean infection will result.Pathogens must enter the bloodstream to causePathogens must enter the bloodstream to causeinfection.infection.

    In the workplace, an employee may be exposedIn the workplace, an employee may be exposedto Hepatitis B Virus or HIV when infected bloodto Hepatitis B Virus or HIV when infected bloodor body fluid is allowed to enter the body byor body fluid is allowed to enter the body bymeans of penetration.means of penetration.

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    The Infectious Disease ProcessThe Infectious Disease Process

    This can occur through:This can occur through:

    a needle sticka needle stick

    a cut or break in the skina cut or break in the skin contact with mucouscontact with mucous

    membranes such as thosemembranes such as those

    of the eye, nose, andof the eye, nose, andmouthmouth

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    The Infectious Disease ProcessThe Infectious Disease Process

    Preventive MeasuresPreventive Measures

    To interrupt the chain ofTo interrupt the chain of

    infection for Hepatitis Virusinfection for Hepatitis Virusor HIV, use the followingor HIV, use the following

    preventive measures:preventive measures:

    Wash your hands to removeWash your hands to remove

    infectious organisms beforeinfectious organisms before

    they can enter the body.they can enter the body.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Wear gloves as aWear gloves as a

    barrier whenbarrier when

    handling blood andhandling blood and

    other body fluids.other body fluids.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Wear faceWear face

    protection whenprotection when

    work tasks includework tasks include

    the potential forthe potential for

    spraying orspraying or

    splattering of bodysplattering of body

    substances.substances.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Use caution whenUse caution when

    handling needleshandling needles

    and other sharpand other sharp

    objects. They canobjects. They can

    penetrate the skinpenetrate the skin

    and create entriesand create entries

    for pathogens.for pathogens.

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    The Infectious Disease ProcessThe Infectious Disease Process

    The safest way toThe safest way tohandle contaminatedhandle contaminatedneedles is to placeneedles is to placethem directly into athem directly into a

    labeled sharpslabeled sharpscontainer withoutcontainer withoutrecapping. Thisrecapping. Thispractice minimizespractice minimizesyour risk of a needleyour risk of a needle

    stick. If your workstick. If your workrequires you to recaprequires you to recapneedles, you will wantneedles, you will wantto learn a special oneto learn a special one--handed techniquehanded technique

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    The Infectious Disease ProcessThe Infectious Disease Process

    Finally, receive a Hepatitis B vaccinationFinally, receive a Hepatitis B vaccination

    to decrease your susceptibility to theto decrease your susceptibility to the

    disease. Presently, no vaccine for HIV isdisease. Presently, no vaccine for HIV is

    available.available.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Mycobacteria (tuberculosis)Mycobacteria (tuberculosis)

    Another group of pathogensAnother group of pathogensknown as Mycobacteria causeknown as Mycobacteria causethe chronic lung diseasethe chronic lung diseasetuberculosis, also known astuberculosis, also known asTB. Although human beingsTB. Although human beingsare the main reservoirs, otherare the main reservoirs, otherprimates, cattle, and swine canprimates, cattle, and swine canalso be reservoirs.also be reservoirs.Tuberculosis is transmittedTuberculosis is transmittedprimarily through the air. Aprimarily through the air. Aperson with an active case ofperson with an active case ofthe disease discharges thethe disease discharges themicroorganisms by coughingmicroorganisms by coughingor sneezing.or sneezing.

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    The Infectious Disease ProcessThe Infectious Disease Process

    InhalationInhalation

    Exposure occurs when others breathe theExposure occurs when others breathe thecontaminated air. Once inhaled, thecontaminated air. Once inhaled, the

    pathogen may lodge in lung tissue andpathogen may lodge in lung tissue and

    produce lesions.produce lesions.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Preventive MeasuresPreventive Measures

    How then can employeesHow then can employees

    protect themselves fromprotect themselves fromairborne diseases suchairborne diseases such

    as tuberculosis?as tuberculosis?

    Wear respiratoryWear respiratory

    protection when workingprotection when working

    with people and animalswith people and animals

    in isolation forin isolation for

    tuberculosistuberculosis

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    The Infectious Disease ProcessThe Infectious Disease Process

    If available,If available,

    participate in yourparticipate in your

    employer'semployer's

    tuberculosistuberculosiscontrol program.control program.

    A skin test isA skin test is

    administered toadministered to

    screen employeesscreen employeesfor exposure tofor exposure to

    TB.TB.

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    The Infectious Disease ProcessThe Infectious Disease Process

    SalmonellaSalmonella

    The next disease,The next disease,salmonellosis, is causedsalmonellosis, is causedby a group of bacteriaby a group of bacteriacalled salmonella. Thecalled salmonella. Themost commonmost commonmanifestation of thismanifestation of thisdisease is acutedisease is acutegastroenteritis orgastroenteritis orintestinal inflammation.intestinal inflammation.

    Both animals andBoth animals andhumans are reservoirs forhumans are reservoirs forthe salmonella organism.the salmonella organism.Diseased animals andDiseased animals andhumans discharge largehumans discharge largenumbers of salmonella innumbers of salmonella in

    their fecestheir feces

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    The Infectious Disease ProcessThe Infectious Disease Process

    IngestionIngestion

    Infection results fromInfection results fromingesting (i.e., throughingesting (i.e., throughthe mouth) salmonellathe mouth) salmonellaorganisms. Employeesorganisms. Employeesmay be exposed to thesemay be exposed to theseorganisms when handlingorganisms when handlingsoiled diapers and linens,soiled diapers and linens,

    fecal specimenfecal specimencontainers, or culturecontainers, or cultureplates used to isolateplates used to isolatesalmonellasalmonella

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    The Infectious Disease ProcessThe Infectious Disease Process

    Preventive MeasuresPreventive Measures

    You can guard against salmonellaYou can guard against salmonella

    exposure by incorporating the followingexposure by incorporating the following

    practices into your daily routine.practices into your daily routine.

    As a first line defense against ingestingAs a first line defense against ingesting

    microorganisms, don't put anything inmicroorganisms, don't put anything in

    your mouth while at work.your mouth while at work.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Wear gloves when your hands will likelyWear gloves when your hands will likely

    come in contact with contaminatedcome in contact with contaminated

    materials.materials.

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    The Infectious Disease ProcessThe Infectious Disease Process

    Wipe counters with a disinfectant afterWipe counters with a disinfectant after

    performing tasks with materials that mayperforming tasks with materials that may

    be contaminated.be contaminated.

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    The Infectious Disease ProcessThe Infectious Disease Process

    And, thoroughlyAnd, thoroughlywash your handswash your handsafter handlingafter handling

    contaminated items.contaminated items.Even microscopicEven microscopicamounts of fecalamounts of fecalmatter may containmatter may contain

    millions ofmillions ofsalmonellasalmonellaorganismsorganisms

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    The Infectious Disease ProcessThe Infectious Disease Process

    In summary, the infectious disease processIn summary, the infectious disease process

    typically consists of three routes of entry:typically consists of three routes of entry:

    PENETRATIONPENETRATION into the bloodstream,into the bloodstream,

    exemplified by Hepatitis B Virus and HIV;exemplified by Hepatitis B Virus and HIV;

    INHALATIONINHALATION of airborne organisms,of airborne organisms,

    illustrated by Mycobacteria; andillustrated by Mycobacteria; and INGESTIONINGESTION of organisms, demonstratedof organisms, demonstrated

    by salmonella.by salmonella.

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