the new education committee ray hoffmann, and nick pajewski, the medical college of wisconsisn and...

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The ‘new’ Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of

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Page 1: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

The ‘new’ Education Committee

Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn

andAndrew Cucchiara

The University of Pennsylvania

Page 2: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 3: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Goals of The Education Committee

1. Provide resources for biostatisticians who teach fellows, junior and senior faculty.

2. Assess the needs and provide additional educational opportunities for GCRC biostatisticians.

Page 4: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Types of Resources

• Journals – Statistics Education Research Journal

• Statistics Notes & Newsletters• AGS Site• GCRC Statisticians• Web Lectures

– Causeweb.org– Epidemilogy Supercourse

• Teaching Statistics Health Sciences Section

Page 5: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 6: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Types of Resources

• Journals – Statistics Education Research Journal

• Statistics Notes & Newsletters• AGS Site• GCRC Statisticians• Web Lectures

– Causeweb.org– Epidemilogy Supercourse

• Teaching Statistics Health Sciences Section

Page 7: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 8: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 9: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 10: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Types of Resources

• Journals – Statistics Education Research Journal

• Statistics Notes & Newsletters• AGS Site• GCRC Statisticians• Web Lectures

– Causeweb.org– Epidemilogy Supercourse

• Teaching Statistics Health Sciences Section

Page 11: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 12: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 13: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 14: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Types of Resources

• Journals – Statistics Education Research Journal

• Statistics Notes & Newsletters• AGS Site

• GCRC Statisticians• Web Lectures

– Causeweb.org– Epidemilogy Supercourse

• Teaching Statistics Health Sciences Section

Page 15: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 16: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 17: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Study Design in Patient Oriented Research

Jonathan J. Shuster, Ph.D ([email protected])

Research Professor of Statistics

Univ. of Florida, College of Medicine

Page 18: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Take-home Messages

• Clinical Trials are an excellent way to answer important public health questions

• They require rigorous design, conduct, and analysis

• They require oversight for safety and confidentiality

• A strong code of ethics is essential

Page 19: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Take-home Messages

• Clinical Trials need to have adequate power to demonstrate a clinically important difference. Non-significant results are inconclusive (rarely if ever showing no difference).

• Sequential monitoring is important for many trials.

Page 20: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 21: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 22: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Modern Statistical Approaches to Data Analysis:

How to get information from data correctly!

Raymond G. Hoffmann, PhDProfessor of Biostatistics

General Clinical Research CenterMedical College of Wisconsin

[email protected]

Page 23: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Outline

• Comparing two Non-normal means – Nonparametric– Bootstrapping– Model Based

• Longitudinal Models with Unequal Time Points

• Missing Values

Page 24: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Types of Resources

• Journals – Statistics Education Research Journal

• Statistics Notes & Newsletters• AGS Site• GCRC Statisticians• Web Lectures

– Causeweb.org– Epidemilogy Supercourse

• Teaching Statistics Health Sciences Section

Page 25: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 26: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 27: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 28: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 29: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 30: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 31: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Types of Resources

• Journals – Statistics Education Research Journal

• Statistics Notes & Newsletters• AGS Site• GCRC Statisticians• Web Lectures

– Causeweb.org– Epidemilogy Supercourse

• Teaching Statistics Health Sciences Section

Page 32: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Teaching Statistics in Health Sciences Section

• Mostly book reviews

• Some Articles on Teaching– E.g.

Page 33: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Types of Resources

• Journals – Statistics Education Research Journal

• Statistics Notes & Newsletters• AGS Site• GCRC Statisticians• Web Lectures

– Causeweb.org– Epidemilogy Supercourse

• Teaching Statistics in the Health Sciences• Software

Page 34: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 35: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania
Page 36: The new Education Committee Ray Hoffmann, and Nick Pajewski, The Medical College of Wisconsisn and Andrew Cucchiara The University of Pennsylvania

Discussion Questions

• What are ‘we’ willing to contribute

• What Educational Materials/Training would be helpful to ‘us’