the power of. cocoa cacao the modern problem population is aging –chronic illness coronary heart...
TRANSCRIPT
![Page 1: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/1.jpg)
The
POWER OF
![Page 2: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/2.jpg)
COCOACACAO
![Page 3: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/3.jpg)
The Modern Problem
• Population is aging– Chronic illness
• Coronary heart disease
• Hypertension• Diabetes mellitus• Obesity• Strokes• Certain cancers• Arthritis• Depression• Dementia• Generalized
inflammation
![Page 4: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/4.jpg)
Cardiovascular Risk Factors
smoking diabetes
High blood pressure
High cholesterol
Estrogen withdrawal
Oxidative stress decrease nitric oxide
Constriction of blood vessels
Blood clots and plaque formation
inflammation
Heart attack strokes
Obesity
![Page 5: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/5.jpg)
Why ? How?
• Oxidation and inflammation
• Decay
When oxygen is burnt or used as fuel
Oxidation occurs forming
Free Radicals
![Page 6: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/6.jpg)
CytokinesPlaque formation
Foam cell
Monocytes
LUMEN
MEDIA
INTIMA
Oxidized LDL
Adhesion molecules
Lp-PLA2
The role of Lp-PLA2 in vascular inflammation
Lyso-PCOxFA
Macrophage
![Page 7: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/7.jpg)
Free Radicals
O O2 NO OH
![Page 8: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/8.jpg)
Free RadicalsFree radicals have been associated with greater than 200 diseases
It is responsible for premature aging, wrinkling of the skin, hardening of the arteries, stiffening of joints, development of cancer
It sets us up for serious illnesses
![Page 9: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/9.jpg)
Nature’s solutionNature has given naturally occurring fruits and vegetables which contain phytochemicals
The pigments, tastes, and colors serve to protect, reproduce, and benefit the plants
One group of phytochemicals are polyphenols and the largest category is flavonoids
![Page 10: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/10.jpg)
The Future of Health
LET FOOD BE THY MEDICINE AND
MEDICINE BE THY FOOD
Hippocrates
![Page 11: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/11.jpg)
The Bodies’ Own Defenses
– Natural anti oxidants– Natural enzyme processes
• Anti oxidants converts free radicals to harmless molecules
– Body needs extra anti oxidants• Exercise chronic illness fever stresses• Diet from natural food phytonutrients
The government is recommending 5-9 servings of fruits and vegetables
![Page 12: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/12.jpg)
![Page 13: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/13.jpg)
Dietary Flavonoids vs. CHD Mortality (Seven Country Study)
UJTJ
SL
DA
MO
ZU
CR
RO
CR
COBE
ZRUS
EF
VK
WF
0
5
10
15
20
25
30
35
0 20 40 60 80
Total Dietary Flavonoids (mg/day)
Ag
e-A
dju
ste
d 2
5-Y
ear
Mo
rtali
ty (
%)
Hertog MGL. Arch Intern Med 1995; 155:381Hertog MGL. Arch Intern Med 1995; 155:381
Age
Ad
just
ed 2
5 ye
ar M
orta
lity
(%)
20 40 60 80
30
0
EF
WF
US
ZR
UJ
SL
TJ
DA
ZU
CRMOVR
BECO
CR
ZR
Total Dietary Flavonoids mg/day
![Page 14: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/14.jpg)
FlavonoidsFlavonoids have the capacity to act as powerful antioxidants by stopping the free radical process and the oxidative process
They also chelate metal ions
Modulate cellular functioning
![Page 15: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/15.jpg)
![Page 16: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/16.jpg)
Testing
• ORAC oxygen radical absorbance capacity
• HORACNORAC
• SORAC
• Total phenolic
• Epicatechin and catechin
![Page 17: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/17.jpg)
![Page 18: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/18.jpg)
COCOA
• Dark unprocessed cocoa– Bitter is better the
highest ORAC value– It is very rich in
flavonoids especially (-)epicatechin (+)
catechin procyanidins
It is loaded with vitamins, minerals, essential fatty acids, fiber
![Page 19: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/19.jpg)
Chocolate is a divine, celestial drink, the sweat of the stars, the vital seed, divine nectar, the drink of the gods, panacea and universal medicine
Geronimo Piperni, 1796
![Page 20: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/20.jpg)
![Page 21: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/21.jpg)
![Page 22: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/22.jpg)
COCOA
• Dark Cocoa why not spoil bitter is better highest ORAC– Rich in flavonoids (-) epicatechin (+) catechin and procyanidins– Vitamins, minerals, essential fatty acids, fiber– Increases good cholesterol– Dilates blood vessels decreases BP platetes stops clots – Anti-inflammatory antihistamine– Helps the blood use insulin better – Helps with depression PEA – Theobromine no caffeine– Memory – Dental caries and gum disease– Arthritis energy
![Page 23: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/23.jpg)
Modern Day Evidence
• Cocoa flavonoids have been associated in medical studies with decreasing
• Cancer• Cardiovascular diseases• Neurodegenerative diseases• Dental diseases• Depression• Inflammatory diseases
![Page 24: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/24.jpg)
Epicatechin
• Properties– Insulin mimetic action– Protective effects on red blood cells( restores
the acetylcholinesterase activity)– Protects against lipid peroxidation– Inhibits platelet aggregration– Preserves pancreatic islet cells– Prevent the digestion and absorption of
carbohydrates– Help normalize blood sugars
![Page 25: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/25.jpg)
(-)Epicatechin and (+) Catechin
• Improves blood flow• Reduce atherosclerotic plaques• Anti neurodegenerative effect protect
brain cells from amyloid beta protein development
• May impact Caco-2 cells (human colon adenocarcinoma cell line)
![Page 26: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/26.jpg)
Cardiovascular healthdark cocoa
• Studies have found:– Stops the oxidative process
of the LDL (bad) cholesterol
– Increases nitric oxide (NO) dilating blood vessels and lowering blood pressure
– decreases platelet formation and clot development
– increases HDL (good) cholesterol and lowers triglycerides
![Page 27: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/27.jpg)
JACN vol 23,No 3, 197-204 (2004)
![Page 28: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/28.jpg)
↓Insulin resistance ↓Blood pressure
Study Design:•N=20, crossover, 15 dIntervention:•100 g dark chocolate bar vs. 90 g white chocolate barResult (dark chocolate):•45% ↓ insulin resistance 10 mm ↓ SBP
![Page 29: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/29.jpg)
(-) Epicatechin vascular function
• Kuna Indians– Drink 4-5 cups of a high flavonoid rich
beverage a day• Decrease blood pressures• Low cholesterol levels• Improved cardiovascular health
• When they move away and stop drinking the beverage they develop cardiovascular diseases
![Page 30: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/30.jpg)
Copyright ©2006 by the National Academy of Sciences
Schroeter, Hagen et al. (2006) Proc. Natl. Acad. Sci. USA 103, 1024-1029
Fig. 3. Proof-of-concept: Vascular response after oral ingestion of (-)-epicatechin
![Page 31: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/31.jpg)
Zutphen Study
• Studied 470 men ages 65-84 and free of chronic illnesses over 15 years
• Those who ate at least 10 grams of dark chocolate a day had a 45-50% reduction in cardiovascular deaths and overall deaths
• They ate more calories overall but tended to be slightly less fat than those who didn’t
• Archives of Internal Medicine 2006 166:411-417
![Page 32: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/32.jpg)
Meta Analysis boosts cocoa’s blood pressure lowering effects
April 2007 Archives of Internal Medicine• 173 participants Germany University of
Cologne• “The magnitude of the hypotensive effects of
cocoa is clinically noteworthy; it is in the range that is usually achieved with monotherapy of beta blockers or ACE inhibitors
• Better than green or black tea (it appeared they had no effect)
• A
![Page 33: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/33.jpg)
Cocoa reduces LDL
• March 2007• 24% increase in HDL cholesterol with a
cocoa group versus 5% in a controlled group
• Showed a reduction in LDL oxidation
• Measured marked urinary increases in epicatechins and catechins
![Page 34: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/34.jpg)
Reverse Blood Vessel Damage
• March 2007• Journal of Cardiovascular Pharmacology• “Within two days… showed a significant
improvement in blood vessel function and researcher noted that impairment of blood flow could almost be reversed with the high flavanol cocoa”
![Page 35: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/35.jpg)
Heart Health and Exercise
• Journal of International Sport Nutrition and Exercise Metabolism
• Elite bicyclists exercised to exhaustion– Given chocolate milk– Gatorade – Carbohydrate replacement drink
• Exercised again • Chocolate milk was the winner
• Journal of International Sport Nutrition and Exercise Metabolism, 2006:16:78-91
![Page 36: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/36.jpg)
Spatial Memory
• Mice study (Journal of Neuroscience)
– Four groups• Running wheel and epicatechins• Epicatechins• Running wheel and nothing else• The typical American lifestyle
– Results• Water maze the best• Running wheel and epicatechins
– Improved Spatial Memory– Showed increase blood vessel growth
–
![Page 37: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/37.jpg)
Neurodegenerative diseases
• Several studies have looked at flavonoids and decreases in:– Parkinson’s disease– Dementia– Polyphenols have been found to delay onset of
Alzheimer's disease. A recent study showed older Japanese-Amercian men and women who drank fruit or vegetable juices three times a week had a 75% reduction of developing Alzheimer's disease. No benefit was seen with supplemental or dietary vitamins like E, C, or betacarotene.
– Neurology Reviews December 2005, pp.44-45.
![Page 38: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/38.jpg)
Diabetes• Numerous studies have shown that the flavonoids in cocoa increase
insulin sensitivity
• ORIGINAL RESEARCH COMMUNICATION• Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a
decrease in blood pressure in healthy persons1,2,3 • Davide Grassi, Cristina Lippi, Stefano Necozione, Giovambattista Desideri and Claudio Ferri 1 From the Department
of Internal Medicine and Public Health, University of L'Aquila, L'Aquila, Italy. • Background: Numerous studies indicate that flavanols may exert significant vascular protection because of their antioxidant
properties and increased nitric oxide bioavailability. In turn, nitric oxide bioavailability deeply influences insulin-stimulated glucose uptake and vascular tone. Thus, flavanols may also exert positive metabolic and pressor effects.
• Results: HOMA-IR was significantly lower after dark than after white chocolate ingestion (0.94 ± 0.42 compared with 1.72 ± 0.62; P < 0.001), and QUICKI was significantly higher after dark than after white chocolate ingestion (0.398 ± 0.039 compared with 0356 ± 0.023; P = 0.001). Although within normal values, systolic blood pressure was lower after dark than after white chocolate ingestion (107.5 ± 8.6 compared with 113.9 ± 8.4 mm Hg; P < 0.05).
• Conclusion: Dark, but not white, chocolate decreases blood pressure and improves insulin sensitivity in healthy persons
• Tomaru , M Dietary Supplementation with Cacao Liquor Proanthocyanidins Prevents Elevation of Blood Glucose Levels in Diabetic Obese Mice Nutrition 2007 1:7
• Insulin sensitivity helping the body utilize sugars better
![Page 39: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/39.jpg)
Neuropathy– recent report in Neurology Review outlines the results of a study
on how diabetes and high blood sugar cause damage to the body in particular causing nerve damage and nerve pain (neuropathy). The findings suggest that oxidative damage to the inner part of the cells cause the cells to die (apoptosis). This damage to the nerve cells cause burning and or numbness in extremities. This numbness further leads to ulcers in feet and often amputations. The oxidation in the body produces superoxide or free radicals which damage the nerve cells at the molecular level (mitochrondrial level). The oxidation is the result of high blood sugars. In one of the reviews of a study on rats that 20% of the nerve cells DNA were damaged only after three months of high blood sugars.
– Vincent AM, McLean LL, Backus C, Feldman, EL Short term
hypergylcemia produces oxidative damage and apoptosis in neurons, FASEB J 2005;19:638-640
![Page 40: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/40.jpg)
Cancer and flavonoids
• Many studies have shown inhibition of cancer cells in lungs, oral, esophagus, stomach, colon, skin, prostate, and breast cancer
• The research is just beginning in this area
Substances found in edible fruits and vegetables ... that exhibit a potential for modulating human metabolism in a manner favorable for cancer prevention.” JADA. 95(4):493-496, 1995
![Page 41: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/41.jpg)
Inflammation
• Studies have shown the flavonoids work like a COX inhibitor blocking the pathway stopping inflammation in the body
• The cocoa flavonoids act as anti histamine helping with asthma and stomach discomfort as well as a potent anti -diarrhea agent
![Page 42: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/42.jpg)
Theobromine increases feeling of well being mild antidepressant
Stimulates muscular system
Not addictive
Opens up the lungs bronchodilator
![Page 43: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/43.jpg)
Mood Elevation
Psychoactive chemicals in cocoa
PEA phenylethylamine love chemical
Anandamide bliss chemical
MAO inhibitorVitamins like magnesiumTryptophan
serotonindopamine
Decrease in depression Mood elevationAppetite depressant
![Page 44: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/44.jpg)
Brain Power
• Study done found that chocolate– Increased verbal and visual memory– Improved impulse and reaction time– Overall enhanced cognitive performance
– Raudenbush, B Wheeling Jesuit University West Virginia soon to be published study, 2006
![Page 45: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/45.jpg)
A Kiss is Just A Kiss
• April 2007• Heartbeats per minutes more than
doubled from eating chocolate than kissing and a more sustained reaction up to four times longer than by a kiss
• The feel good factor from serotonin
![Page 46: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/46.jpg)
Neurobiology of Chocolate
• University of Nottingham Medical School 2007
• “Our study showed that acute consumption of flavanol-rich cocoa was associated with increased grey matter flow for two to three hours… it raises the possibility that cocoa maybe beneficial in enhancing brain function … helping with fatigue, sleep, deprivation, ageing, and even dementia”
![Page 47: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/47.jpg)
Flavonoids improve mental health
• June 2007– Better cognitive performance done over 10
years– It improved the Mini Mental State
Examination
![Page 48: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/48.jpg)
Aging
• Studies recently done with animals show improvement in aging with a diet high in flavonoids and antioxidants
• It slowed down the aging process• Prior USDA, 2005
![Page 49: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/49.jpg)
Other Areas
• Flavonol rich diet may slash pancreatic cancer risks
• American Association for Cancer Research may cut risk by 25% up to 59% in smokers
• “Anti carcinogenic effects of flavanoids in general have been attributed to the ability of these constituents to inhibit cell cycle, cell proliferation and oxidative stress, and to induce detoxification enzymes and apotosis”
![Page 50: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/50.jpg)
Other Medical Properties• Cocoa protects the sun from UV damage and
helps reducing wrinkles and skin damage• Cocoa has been found to help with diarrhea• Stop smoking cravings• Helps with inflammatory bowel diseases• Macular degeneration • Weight Loss (Bodybyxocolate.com)• Great during pregnancy and lactation –sweet
babies
![Page 51: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/51.jpg)
Myths• Rarely are people allergic to chocolate• Does not increase acne• Does not cause migraine headaches• Does not increase acid reflux• Does not increase your weight• Does not cause insomnia• Pure cocoa beans have no to minimal
caffeine• Milk does not interfere with absorption
![Page 52: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/52.jpg)
Fiber
• Cocoa Fiber– Feel fuller faster– Helps with irritable bowel syndrome– Lowers blood sugars– Lowers cholesterol– Colon
![Page 53: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/53.jpg)
Cocoa Butter
• Made up of – Stearic acid (34%)– Oleic acid (34%)– Palmitic acid (25%)– Others (7%)
• Neutral in regard to lipid profile and weight gain
![Page 54: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/54.jpg)
Dental Health
• Prevention and healing of gum disease
• Prevention of dental caries
• Two studies done this year in Japan showed decrease in oral bacteria counts resulting in improved breath
![Page 55: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/55.jpg)
Should it be a Vitamin???Vitamin-C(ocoa)
• “Epicatechin could potentially get rid of
FOUR of the five most common diseases in the Western World –
In Kuna Indians 90% less risk of cancer, stroke, heart failure and diabetes
![Page 56: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/56.jpg)
• Need a cocoa that is raw unprocessed cold pressed cocoa not heated– Without the added high glycemic sugars –
refined sugars, added fats, waxes, preservatives, tested for lead and bacteria
– Mixed with other high antioxidant fruits or products
– Avoid Dutching or alkalization
![Page 57: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/57.jpg)
XOCAI
• Xocai has the great benefits of not only cocoa but Acai Omega 3 blueberries dark grapes
• The weighted benefits far outweight any minor problem with any individual component
![Page 58: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/58.jpg)
Effectiveness of Cocoa Flavonoids
• “This does not preclude the possibility that flavonoids may accumulate in tissues where they might exert local antioxidant effects or that very low concentrations of flavonoids may modulate cell signalling, gene regulation, antiogenesis,and other biological processes by non-antioxidant mechanisms, which may explain the purported health benefits of flavonoids”
• Free Radical Biology and Medicine
![Page 59: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/59.jpg)
Ideal Primary Prevention Agent• Natural dietary factor (not a
medicine)• Palatable—even tasty• Convenient• Affordable/available• Positive incentives to use regularly• Feasible for long-term adherence• Supplement or partial replacement• Maximizes positive elements• Minimizes negative elements• Scientifically established
– Benefits– Safety
![Page 60: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/60.jpg)
The Antioxidant ParadoxOxidation promotes CVD, andLow CVD risk associates with:• A diet high in antioxidant-rich foods
associates with low CVD risk• High blood levels of antioxidants,
butAntioxidant vitamins do not lower
CVD risk!Why not?
Somehow the benefit is lost:• Other important antioxidants are
removed, and/or • Antioxidants need to be with other
factors in the food
![Page 61: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/61.jpg)
WEIGH THE EVIDENCE
• For centuries cocoa was a medicine
• TODAY new studies are tipping the balance again in favor of flavonoids and especially cocoa phytonutrients combined with a balanced diet and active life
![Page 62: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/62.jpg)
• FOR MORE INFORMATION:– The Power of Dark Chocolate by Steven Warren MD
–
– www.mydrchocolate.com– www.healthchocolatetools.com
– Health Matters with Dr Steve TV this Fall
![Page 63: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/63.jpg)
![Page 64: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/64.jpg)
![Page 65: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/65.jpg)
![Page 66: The POWER OF. COCOA CACAO The Modern Problem Population is aging –Chronic illness Coronary heart disease Hypertension Diabetes mellitus Obesity Strokes](https://reader036.vdocument.in/reader036/viewer/2022081519/56649cc55503460f9498e5f5/html5/thumbnails/66.jpg)