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The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

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Page 1: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

The Systems, Structures, and Cells That Make Up Your Nervous System

Chapter 3The Anatomy of the Nervous System

Page 2: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

General Layout of the Nervous System Central Nervous System (CNS)

Brain (in the skull) Spinal Cord (in the spine)

Peripheral Nervous System (PNS) Located outside of the skull and spine Serves to bring information into the CNS and carry

signals out of the CNS

Page 3: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Major divisions of the nervous system

Page 4: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Meninges, Ventricles, and Cerebrospinal Fluid (CSF) CNS encased in bone and

covered by three meninges Dura mater – tough outer membrane Arachnoid membrane – web-like Pia mater – adheres to CNS surface

Cerebrospinal fluid (CSF) Fluid serves as cushion

Page 5: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Meningeshttp://faculty.une.edu/com/fwillard/Meninges/pages/mening02.htm

http://faculty.une.edu/com/fwillard/Meninges/pages/mening02.htm

Page 6: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Protecting the Brain

Chemical protection The blood-brain barrier – tightly-

packed cells of blood vessel walls prevent entry of many molecules

Physical protection Skull Meninges Cerebrospinal fluid (CSF)

Page 7: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Cells of the Nervous System Neurons

Specialized cells for the reception, conduction, and transmission of electrochemical signals

Many sizes and shapes Glial cells

Outnumber neurons 10:1

Page 8: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Major external features of

a typical neuron

Cells of theNervousSystem

Page 9: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

The cell

mem-brane

Cells of the Nervous System (continued)

Page 10: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Cells of the Nervous System (continued)

Fourtypes

ofneurons

Page 11: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Glial Cells: The Forgotten Majority

Four classes: Oligodendrocytes – extensions rich in myelin create

myelin sheaths in CNS Schwann cells – similar to function of oligodendrocytes

but in PNS, can guide axonal regeneration Astrocytes – largest glia, star-shaped, many functions Microglia – involved in response to injury or disease

Page 12: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System
Page 13: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Page 14: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Terminology NoteCNS PNS

Myelin-providing glia

Oligodendrocytes Schwann cells

Clusters of cell bodies

Nuclei (singular nucleus)

Ganglia(singular ganglion)

Bundles of axons Tracts Nerves

Page 15: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Neuroanatomical Techniques Golgi stain – allows for

visualization of individual neurons

Nissl stain – selectively stains cell bodies

Electron microscopy – provides information about the details of neuronal structure

Page 16: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Neuroanatomical Tracing Techniques

Anterograde (forward) tracing where axons project

away from an area Retrograde (backward)

tracing where axons are projecting into an area

Page 17: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Directions in the Vertebrate Nervous System

Page 18: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Directions in the Vertebrate Nervous System (continued)

Page 19: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Directions in the Vertebrate Nervous System (continued)

Anatomical directions ignore the fact that humans walk upright. Therefore, top of the head both “dorsal” (back) and “superior” (top)

Other directions: Medial – toward the middle Lateral – toward the side Proximal – close Distal – far

Page 20: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Sections of the Brain

Horizontal – a slice parallel to the ground

Frontal (coronal) – slicing bread or salami

Sagittal – a midsagittal section separates the left and right halves

Page 21: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon section

Page 22: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

The Spinal Cord Gray matter – inner component,

primarily cell bodies White matter – outer area, mainly

myelinated axons Dorsal – afferent, sensory Ventral – efferent, motor

Page 23: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

The Spinal Cord (continued)

Dorsal and ventral roots Spinal cross section

Page 24: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

The Five Major Divisions of the Brain

Early develop-

ment of themammalian

brain

Page 25: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

The Five Major Divisions of the Brain (continued)

The divisionsof the adult

human brain

Page 26: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Major Structures of the Brain Myelencephalon = medulla

Composed largely of tracts Origin of the reticular formation

Metencephalon Many tracts Pons – ventral surface Cerebellum – coordination

Page 27: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Structures of thehuman

myelencephalon(medulla) and

metencephalon

Major Structures of the Brain

Page 28: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Major Struc-tures of theBrain (continued)

The humanmesencephalon

(midbrain)

Page 29: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

(continued)

Major Structures of the Brain

The humandiencephalon

Page 30: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Telencephalon – Cerebral Cortex Convolutions serve to increase

surface area Longitudinal fissure – a groove

that separates right and left hemispheres

Corpus callosum – largest hemisphere-connecting tract

Page 31: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Major fissures of the cerebral hemispheres Lobes of the cerebral hemispheres

Page 32: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

Telencephalon – Subcortical Structures

Limbic system – regulation of motivated behaviors Mammillary bodies, hippocampus,

amygdala, fornix, cingulate, septum Basal ganglia motor system

Amygdala, striatum (caudate nucleus + putamen), globus pallidus

Page 33: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

The major structures of

the limbicsystem

Telencephalon – Subcortical Structures

Page 34: The Systems, Structures, and Cells That Make Up Your Nervous System Chapter 3 The Anatomy of the Nervous System

Copyright © 2009 Allyn & Bacon

The basal ganglia

Telencephalon – Subcortical Structures

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Copyright © 2009 Allyn & Bacon

Summary of major brain structures