the truth about bio-identical hormones
DESCRIPTION
Holistic physician, Dr. Vivian DeNise explains the difference between bio-identical hormone replacement therapy and synthetic hormones. She also details symptoms and medical conditions that may result from unbalanced hormones and benefits of getting balanced by an expert holistic doctor.TRANSCRIPT
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The Truth About Bio-Identical Hormones
Vivian F. DeNise,DO Integrative PhysicianPatients Medical
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Patients Medical
A holistic medical centerFull-service
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Patients Medical
Discover health, rediscover vitalityFocus on the root cause Integrate modern medicine, holistic
practices, and natural supplements
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Patients Medical
Our goal Promote healing and prevent disease
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Patients Medical
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Result: Gain health and nutritional wisdom
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Patients Medical
Founder, Dr. Warren Levinbegan practicing his ground-breaking
holistic protocols in 1974.
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Patients Medical
Integrative Medicine
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Patients Medical
Introducing our speaker:
Vivian DeNise, DOIntegrative Medicine
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Patients Medical
Completed her medical degree at New York College of Osteopathic Medicine
Certifications in Integrative Medicine with the American Academy of Anti-Aging Medicine (A4M)
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Patients Medical
Specialties include Hormonal Imbalances Nutritional Deficiency Thyroid Disorders Gastro-Intestinal Problems Detoxification And many more!
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The Truth About Bio-Identical Hormones
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Hormone Receptors
There are receptors everywhere in the body for estrogen, progesterone and
testosterone in both men and women.
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Where are they?
BrainBone, Muscle, JointsHeartBlood VesselsBladderLiverKidneyGenitalsNervesSkin and Hair Follicles
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What is our goal?
To achieve Balanced Hormone Optimization to that of a 25-30 year old level using Bio-Identical Hormones.
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What are Natural (Bio-Identical) Hormones?
They are identical to the molecular structure of hormones produced by human female or males.
They are NOT: Xeno hormones Horse hormones Synthetic hormones
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What Bio Identical Hormones Are
Atom for atom identical to human hormones Not horse hormones Not chemically altered
No increased risk for cancerLess risk for heart diseaseLess mortalityNeeded for Bone, Brain, Quality of
Life
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The Hormonal Symphony
TestosteroneEstrogens,
ProgesteroneDHEA, PregnenaoloneCortisolThyroid: T3, T4Vitamin DGrowth Hormone
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Your Libido is Affected By
Hormones Neurotransmitters Medications Emotions Diet Sleep
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Female Hormones
Estrogens▪ Estrone=E1▪ Estradiol=E2▪ Estriol=E3
ProgesteroneTestosterone
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Hormones
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Definitions
PMS (Premenstrual Syndrome)- Cyclical mental and physical symptoms
preceding the menstrual cycle.
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Definitions
Peri-menopause-Can begin to occur 10-20 years prior to menopause associated with cyclical changes in menses as well as mental/physical symptoms.▪ Early- changes occur rarely and resolve▪ Middle-changes occur often and for longer▪ Late-changes occur continuously.
Menopause-no menstrual bleeding for 1 year
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Female Hormones
Deficiencies can start years before menopause in peri-menopause Poor sleep, anxiety,
PMS-Progesterone Low Libido, decreased
memory-Testosterone Low energy, hot flashes,
vaginal dryness-Estrogen
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Bio Identical Hormone Replacement in Women
Balances Estrogens, Progesterone, and Testosterone
Every woman needs a unique balance
Not every woman needs estrogenProgesterone protects against breast
cancer
Unlike “progestins” natural progesterone does not have
androgenic or anti androgenic effects.
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Estrogen Deficiency
Hot flashesNight sweatsFatigueVaginal DrynessPoor memory
and Foggy thinking
Low energy
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Estrogen Deficiency
Depressed mood Decreased
concentration Decreased sexual
desire or libido Excessive daytime
sleepiness Stress incontinence and
UTI’s Osteoporosis,
Cardiovascular disease, Dementia www.patientsmedical.com
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Excess Estrogen Side effects
Agitated Anxiety Weight gain Water retention Headaches Swollen or tender breasts Bloating Spotting or breakthrough
bleeding Mood swings Poor sleep Achy joints Excessive bleeding
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Synthetic Estrogen
Increase blood pressure Increase triglycerides Increase estroneCause gallstonesElevate liver enzymes Increase SHBG (decreases
testosterone) Interrupt tyrptophan metabolism
and consequently serotonin metabolism
Causes blood clots to formwww.patientsmedical.com
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What Transdermal E2 doesDecreases HbA1cDecreases total cholesterolDecreases LDLDecreases HS-CRPDecreases IL-6 and TNF-inflammatory
cytokines implicated in autoimmune, cardiovascular, osteoporosis and Alzheimer's
NO increase risk of stroke or venous thrombosis
Protects against bone losswww.patientsmedical.com
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Progesterone
Usually the first hormone to become deficient in peri-menopause.
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Progesterone deficiency symptoms
Agitation Irritability, aggressiveness Anxiety, anger Weight gain Water retention Headaches Swollen or tender breasts
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Progesterone Deficiency Symptoms
BloatingSpotting or breakthrough bleedingMood swingsPoor sleep, insomniaAchy jointsExcessive bleedingEndometriosisFibrocystic breasts
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Causes of Low Progesterone Impaired production Low LH Increased prolactin productionStressAntidepressantsExcessive arginine consumptionSugarSaturated fatDeficiency of vitamins A, B6, C, zincDecreased thyroid hormone
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Synthetic Progesterone
Called progestinsProgestins do not reproduce the
same actions of natural progesterone
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Side Effects of Synthetic Progesterone
Increases appetiteWeight gainFluid retention IrritabilityDepressionHeadacheDecreases energyBloatingBreast tendernessDecreases sexual interest
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Side Effects of Synthetic Progesterone
AcneHair lossNausea Insomnia Interferes with the body’s own
production of progesteroneDoes not help balance estrogenRemains in the body longerCan cause spasm of coronary arteries
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Wait there’s more…….
Stops the protective affects estrogen has on the heart
May make the symptoms of progesterone loss worse
Increases LDLDecreases HDLProtects only the uterus from cancerCounteracts many of the positive
effects of estrogen on serotonin
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Bio-Identical Progesterone Replacement
OrallyTransdermal cream
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Natural Progesterone Affects Not Seen With Progestins
Helps balance estrogenLeaves the body quickly Improves sleepNatural calming effectLowers high blood pressureHelps the body use and eliminate fatsLowers cholesterol
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Natural Progesterone Affects Not Seen With Progestins (Continued)
May protect against breast cancer Increases scalp hair Helps balance fluids in the cells Increases metabolic rate Natural diureticNatural antidepressant Is anti-inflammatory
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Natural Progesterone Affects Not Seen With Progestins (Continued)
Stimulates the production of new bone
Enhances the action of thyroid hormones
Improves libido Helps restore proper
cell oxygen levels Induces conversion of
E1 to the inactive E1S form
Promotes Th2 immunity
Is neuroprotective, promoting myelination
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Progesterone Decreases Breast Cancer Risk
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Synthetic progestins increase Breast Cancer Risk
Progesterone decreases Breast Cancer Risk
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Effects of Too Much Progesterone Even with Adequate Estrogen
Increases fat storageElevates cortisol Increases insulin resistance Increases appetite and carbohydrate
cravingsRelaxes the smooth muscles of the
gut (This can cause bloating, fullness, and constipation. It can also contribute to gallstones.)
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Testosterone Replacement in Women
Testosterone is needed for a sense of well being
Strength especially upper bodyLibidoUsually decreased in peri-menopausal
and menopausal womenBody composition Bone densityDHEA can increase Testosterone in
women but not in menwww.patientsmedical.com
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Testosterone
Increases sexual interest
Increases sense of emotional well-being
Increases muscle mass and strength
Helps maintain memoryHelps skin from saggingDecreases excess body
fatHelps maintain bone
strengthElevates
norepinephrine in the brain (tricyclic affect)
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Symptoms of Testosterone LossMuscle wastingWeight gainFatigueLow self-esteemDecreased HDLDry, thin skin, with
poor elasticityThinning and dry
hairDroopy eyelidsSagging cheeksThin lipsAnxiety
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Causes of Low TestosteroneMenopauseChildbirthChemotherapyAdrenal stress or burnoutEndometriosisDepressionPsychological traumaBirth control pillsHMG-CoA-reductase inhibitors
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Treatment of Low Testosterone Testosterone replacement P.O. or
transdermally. Use the bio-identical form.
Methyltestosterone has been associated with an increase in liver cancer.
If used transdermally must rotate sites. In order for testosterone to work well,
estradiol must also be optimized. Without enough estrogen, testosterone
cannot attach to brain receptors. If testosterone is given alone it can
increase plaque formation. www.patientsmedical.com
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How Else Can Testosterone Levels Be Raised?
Decrease calorie intake Increase protein in the
dietTake the amino acids
arginine, leucine, glutamine
ExerciseGet enough sleepLose weightReduce stressTake zinc if deficient
(Zinc is needed for the metabolism of testosterone.)
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Testosterone Replacement Therapy Decreases Breast Cancer
When used in conjunction with BHRT there is even a lower incidence of
breast cancer compared to HRT alone.
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Follow-Up
Seen every 3 months or sooner if needed
Labs every 3 months initially and as needed depending on where patient is in life
May take up to 6 months to get full benefit
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Other Factors
StressDietEnvironmental
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Get on track with your health!
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Do you have a question for Dr. DeNise? Ask it Now!
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Please fill out your pink event evaluation form and return it to us.
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Get on Track with Your Hormonal Health!
Get started TODAY by making an appointment with Dr. DeNise.
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