tissues and tissue types
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Tissues are:• Collections of specialized cells and cellproducts organized to perform a limitednumber of functions Histology = study of tissues
The four tissue types are:
• Epithelial
• Connective• Muscular
• Nervous
Tissues and tissue typesTissues and tissue types
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Epithelial tissue Layer of cells covering exposed body surfaces inside or
outside
• Skin
• Linings of body cavities
• Linings of any body opening• Linings of internal passageways
Form barriers Form glands
• Secretory structures from epithelium
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Characteristics of epitheliumCharacteristics of epithelium
CellularityCellulari
ty: composed of tightly bound, arranged cells: composed of tightly bound, arranged cells
Polarity:Polar
ity:
uneven distribution of materials in cells;uneven distribution of materials in cells;
one side always faces an opening;one side always faces an opening;
one side always attached to a basement membrane toone side always attached to a basement membrane toadjacent tissueadjacent tissue
Attachment:Attachment:
one side always attached to membrane made byone side always attached to membrane made byepithelium (basal membrane) & connective tissueepithelium (basal membrane) & connective tissueunderneathunderneath
Avascularity:Avascular
ity:
No blood vessels in epitheliumNo blood vessels in epithelium
Nourished by diffusion or absorptionNourished by diffusion or absorption
RegenerationR
egeneration
Surface cells replaced continually by mitotic cells belowSurface cells replaced continually by mitotic cells below
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Epithelial functionEpithelial function
1. Provide physical protection1. Provide physical protection
Protect from abrasion, dehydration,…Protect from abrasion, dehydration,…
2. From a barrier for permeability2. From a barrier for permeability
Can give selective absorption or secretionCan give selective absorption or secretion
Can be regulated & modified by stimuli, I.e.,Can be regulated & modified by stimuli, I.e.,changed with needchanged with need
3. Provide sensations:3. Provide sensations:
Epithelial cells deeply innervated w. sensory nervesEpithelial cells deeply innervated w. sensory nerves
Detect changes in environment & relay to bodyDetect changes in environment & relay to body
4. Produce specialized secretions4. Produce specialized secretions
Glandular epithelium may be scattered in otherGlandular epithelium may be scattered in otherepitheliumepithelium
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Classification of EpitheliumClassification of Epithelium
Classified by arrangement of cells into layersClassified by arrangement of cells into layers• simple = one cell layer thicksimple = one cell layer thick
• stratified = many cell layers thickstratified = many cell layers thick
• pseudostratified = single layer of cells where all cellpseudostratified = single layer of cells where all celldon’t reach apical surfacedon’t reach apical surface nuclei at found at different levels so it looks multilayerednuclei at found at different levels so it looks multilayered
Classified by shape of surface cellsClassified by shape of surface cells• squamous =flatsquamous =flat
• cuboidal = cube-shapedcuboidal = cube-shaped
• columnar = tall columncolumnar = tall column
• transitional = shape varies with tissue stretchingtransitional = shape varies with tissue stretching
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SquamousSquamousSimple squamousSimple squamous
In protected regions for absorptionIn protected regions for absorption• Respiratory alveoli for gas exchangeRespiratory alveoli for gas exchange
In regions to reduce frictionIn regions to reduce friction• Linings of blood vessels & heart = endotheliumLinings of blood vessels & heart = endothelium• Serous membranes lining body cavitiesSerous membranes lining body cavities• MesotheliumMesothelium = any simple squamous epithelium lining= any simple squamous epithelium lining
ventral body cavitiesventral body cavities
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Single row of cube-shaped cells, often with microvilli.
• Absorption & secretion; produces mucus.
Mammary and salivary glands.
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Single row of tall, narrow cells
• vertically oriented, oval nuclei in basal half of cell Absorption & secretion; secretion of mucus Inner lining of GI tract
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Keratinized Stratified SquamousKeratinized Stratified Squamous
Multilayered epithelium covered with layer of compact, dead squamous cells packed with proteinkeratin
Retards water loss & prevents penetration of organisms
N k i i d S ifi d
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Nonkeratinized StratifiedNonkeratinized Stratified
SquamousSquamous
Multilayered epithelium that lacks surfacelayer of dead cells forming abrasion-resistant,moist, slippery layer
Found on ton ue & va ina
Epithelial
layer
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Stratified Cuboidal EpitheliumStratified Cuboidal Epithelium
Two or more layers of cells; surface cells square
Secretes sweat; ovarian hormones & produces sperm
Found ovarian follicles & seminiferous tubules
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Cuboidal EpitheliaCuboidal Epithelia
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Transitional EpitheliumTransitional Epithelium
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Transitional EpitheliumTransitional Epithelium
Multilayered epithelium with rounded
surface cells that flatten when the tissueis stretched
Stretches to allow filling of urinary tract
Found in urinary tract -- urinary bladder
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Specialized for contractionSpecialized for contraction
Three typesThree types
• SkeletalSkeletal• CardiacCardiac
• SmoothSmooth
Muscle tissueMuscle tissue
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Muscle TissueMuscle Tissue
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Muscle TissueMuscle Tissue
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Muscle TissueMuscle Tissue
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Establishing a structural frameworkEstablishing a structural framework
Transporting fluids and dissolvedTransporting fluids and dissolvedmaterialsmaterials
Protecting delicate organsProtecting delicate organs
Supporting, surrounding andSupporting, surrounding and
interconnecting tissuesinterconnecting tissues
Storing energy reservesStoring energy reserves
Defending the body from microorganismsDefending the body from microorganisms
Connective tissue functionsConnective tissue functions
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A Classification of ConnectiveA Classification of Connective
TissuesTissues
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Specialized cellsSpecialized cells
MatrixMatrix• Composed of extracellular protein fibersComposed of extracellular protein fibers
and a ground substanceand a ground substance
Connective tissues containConnective tissues contain
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Contains varied cell populationsContains varied cell populations
Contains various fiber typesContains various fiber types A syrupy ground substanceA syrupy ground substance
Connective tissue proper Connective tissue proper
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Fluid connective tissueFluid connective tissue
Contains a distinctive cell populationContains a distinctive cell population
Watery ground substance withWatery ground substance with
dissolved proteinsdissolved proteins
Two typesTwo types
• BloodBlood
• LymphLymph
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Less diverse cell populationLess diverse cell population
Dense ground substanceDense ground substance
Closely packed fibersClosely packed fibers
Two typesTwo types
• CartilageCartilage
• BoneBone
Supporting connective tissuesSupporting connective tissues
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Contains fibers, a viscous groundContains fibers, a viscous ground
substance, and a varied cell populationsubstance, and a varied cell population• FibroblastsFibroblasts
• MacrophageMacrophage
• AdipocytesAdipocytes• Mesenchymal cellsMesenchymal cells
• MelanocytesMelanocytes
• Mast cellsMast cells• LymphocytesLymphocytes
• MicrophagesMicrophages
Connective tissue proper Connective tissue proper
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Classified as loose or denseClassified as loose or dense LooseLoose
• Embryonic mesenchyme, mucous connectiveEmbryonic mesenchyme, mucous connective
tissuestissues
• Areolar tissueAreolar tissue
• Adipose tissueAdipose tissue
• Reticular tissueReticular tissue
DenseDense• Dense regular CTDense regular CT
• Dense irregular CTDense irregular CT
Connective tissue proper Connective tissue proper
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The Cells and Fibers of The Cells and Fibers of
Connective Tissue Proper Connective Tissue Proper
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Connective Tissue in EmbryosConnective Tissue in Embryos
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Adipose and Reticular TissuesAdipose and Reticular Tissues
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Dense Connective TissuesDense Connective Tissues
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Dense Connective TissuesDense Connective Tissues
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Dense Connective TissuesDense Connective Tissues
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Distinctive collections of cells in a fluidDistinctive collections of cells in a fluid
matrixmatrix
BloodBlood
• Formed elements and plasmaFormed elements and plasma Red blood cells, white blood cells and plateletsRed blood cells, white blood cells and platelets
• Arteries carry blood away, veins carry toArteries carry blood away, veins carry to
the heartthe heart• Capillaries allow diffusion into theCapillaries allow diffusion into the
interstitial fluidinterstitial fluid
LymphLymph
Fluid connective tissuesFluid connective tissues
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Formed Elements of the BloodFormed Elements of the Blood
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Cartilage and bone support the rest of the bodyCartilage and bone support the rest of the body
CartilageCartilage
• Grows via interstitial and appositional growthGrows via interstitial and appositional growth
• Matrix is a firm gel containing chondroitin sulfateMatrix is a firm gel containing chondroitin sulfate
• Cells called chondrocytesCells called chondrocytes
• Cells found in lacunaeCells found in lacunae
• Perichondrium separates cartilage fromPerichondrium separates cartilage fromsurrounding tissuessurrounding tissues
• Three types: hyaline, elastic and fibrocartilageThree types: hyaline, elastic and fibrocartilage
Supporting connective tissuesSupporting connective tissues
The Perichondrium and Types ofThe Perichondrium and Types of
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The Perichondrium and Types of The Perichondrium and Types of
CartilageCartilage
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The Perichondrium and Types of The Perichondrium and Types of
CartilageCartilage
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The Perichondrium and Types of The Perichondrium and Types of
CartilageCartilage
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Has osteocytesHas osteocytes
• Depend on diffusion throughDepend on diffusion throughcanaliculi for nutrientscanaliculi for nutrients
Little ground substanceLittle ground substance
Dense mineralized matrixDense mineralized matrix Surrounded by periosteumSurrounded by periosteum
Bone, or osseus tissueBone, or osseus tissue
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BoneBone