transcription in eukaryotes class ii promoters: *core promoter tata box tfiib recognition element...
Post on 19-Dec-2015
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![Page 1: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/1.jpg)
Transcription in EukaryotesClass II promoters:
*Core Promoter
TATA box
TFIIB Recognition Element (BRE)
Initiator (Inr)
Downstream Promoter Element (DPE)
*Upstream Promoter Element
![Page 2: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/2.jpg)
Transcription Initiation in Eukaryotes
General Transcription Factors and the Pre-initiation complex:
![Page 3: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/3.jpg)
Transcription Initiation in EukaryotesTBP binding:
![Page 4: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/4.jpg)
Transcription Initiation in Eukaryotes
![Page 5: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/5.jpg)
Transcription Initiation in Eukaryotes
![Page 6: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/6.jpg)
Schematic ModelElongation of Transcription in Eukaryotes
![Page 7: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/7.jpg)
Polyadenylation
*CstF
*CPSF
*PAP
*PABP
RNA processing in eukaryotesAddition of poly A tail
Addition of 5’cap
Splicing
![Page 8: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/8.jpg)
Torpedo model for transcription termination
![Page 9: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/9.jpg)
Formation of the 5’ cap
*RNA triphosphatase
*guanylyl transferase
*methyl transferase
Transcript Processing
![Page 10: Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE)](https://reader030.vdocument.in/reader030/viewer/2022032800/56649d2f5503460f94a077a5/html5/thumbnails/10.jpg)
Functions of the Cap and Tail
ProtectionTranslatability TransportSplicing